qx-314 and bupivacaine

qx-314 has been researched along with bupivacaine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, GK1
Geddis, LM; Kutchai, H1
Bischoff, U; Bräu, ME; Hempelmann, G; Olschewski, A; Vogel, W1
Akiyuki, S; Kawamata, M; Kawamata, T; Shimizu, F; Tanaka, S1
Bean, BP; Brenneis, C; Cobos, EJ; Ferreirós, N; Geisslinger, G; Jo, S; Kistner, K; Labocha, S; Puopolo, M; Reeh, PW; Roberson, D; Segal, D; Sisignano, M; Tran, J; von Hehn, C; Wainger, BJ; Woolf, CJ1
Li, J; Liu, J; Lv, R; Ma, L; Yang, X; Yin, Q; Zhang, W; Zheng, Q; Zhu, T1
Liu, J; Yang, J; Yang, L; Yin, Q; Zhang, W; Zhang, Y1
Andrews, NA; Bean, BP; Heckman, LM; Jacquemont, T; Jain, A; Jo, S; Kotoda, M; Lee, J; Lee, S; Liu, PW; Pascal, M; Puopolo, M; Talbot, S; Woolf, CJ; Zhang, HB1

Reviews

1 review(s) available for qx-314 and bupivacaine

ArticleYear
[Potentials for differential block with local anesthetics].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Drug Design; Humans; Levobupivacaine; Lidocaine; Nociceptors; Physical Stimulation; Sodium Channel Blockers; Sodium Channels; TRPV Cation Channels

2010

Other Studies

7 other study(ies) available for qx-314 and bupivacaine

ArticleYear
Cocaine-induced closures of single batrachotoxin-activated Na+ channels in planar lipid bilayers.
    The Journal of general physiology, 1988, Volume: 92, Issue:6

    Topics: Anesthetics, Local; Animals; Batrachotoxins; Binding Sites; Bupivacaine; Cocaine; Dose-Response Relationship, Drug; Electrophysiology; Lidocaine; Lipid Bilayers; Muscles; Rabbits; Sodium Channels

1988
Inhibition of the Na,K-ATPase of canine renal medulla by several local anesthetics.
    Pharmacological research, 2001, Volume: 43, Issue:4

    Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Dogs; Kidney Medulla; Lidocaine; Mepivacaine; Procaine; Protein Binding; Ropivacaine; Sodium Channels; Sodium-Potassium-Exchanging ATPase

2001
Local anaesthetics block hyperpolarization-activated inward current in rat small dorsal root ganglion neurones.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Inhibitory Concentration 50; Ion Channels; Lidocaine; Mepivacaine; Neurons; Potassium Channels; Pyrimidines; Rats; Tetraethylammonium; Time Factors

2003
Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.
    British journal of pharmacology, 2014, Volume: 171, Issue:2

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Calcium; Cell Line; Foot Injuries; Ganglia, Spinal; Injections; Lidocaine; Male; Mice, Knockout; Nerve Block; Patch-Clamp Techniques; Peripheral Nerves; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Transient Receptor Potential Channels; TRPA1 Cation Channel

2014
The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Anesthetics, Local; Animals; Bupivacaine; Lidocaine; Male; Models, Theoretical; Nerve Block; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Treatment Outcome

2017
QX-OH, a QX-314 derivative agent, produces long-acting local anesthesia in rats.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jul-15, Volume: 105

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Lidocaine; Male; Muscle, Skeletal; Nerve Block; Rats, Sprague-Dawley; Reflex; Sciatic Nerve

2017
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
    eLife, 2019, 11-25, Volume: 8

    Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Disease Models, Animal; Ganglia, Spinal; Humans; Lidocaine; Mice; Neurogenic Inflammation; Nociceptors; Pain; Sodium Channel Blockers; Sodium Channels

2019