quisqualic acid has been researched along with glycine in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (11.36) | 18.7374 |
| 1990's | 58 (65.91) | 18.2507 |
| 2000's | 17 (19.32) | 29.6817 |
| 2010's | 3 (3.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Baker, BN; Glendenning, KK; Hutson, KA; Masterton, RB | 1 |
| Nomura, Y; Tohda, M; Urushihara, H | 1 |
| Duman, RS; Hayward, MD; Nestler, EJ; Tallman, JF; Vaccarino, FM | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Randic, M; Rusin, KI; Ryu, PD | 1 |
| Akaike, N; Ikemoto, Y; Wakamori, M | 1 |
| Akaike, N; Ito, C; Wakamori, M | 1 |
| Albuquerque, EX; Alkondon, M; Aronstam, RS; Costa, AC; Radhakrishnan, V | 1 |
| Dichter, M; Morad, M; Tang, CM | 1 |
| Kline, PA; Nowak, LM; Wright, JM | 1 |
| Larson, AA; Sun, XF | 1 |
| Baker, BN; Glendenning, KK; Masterton, RB; Wenthold, RJ | 1 |
| Grudt, TJ; Jahr, CE | 1 |
| Nistri, A; Sivilotti, L; Welsh, DM | 1 |
| DiFiglia, M; Freese, A; Koroshetz, WJ | 1 |
| Cler, JA; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Thomson, AM | 1 |
| Akaike, N; Murase, K; Nakagawa, T; Randic, M; Shirasaki, T | 1 |
| Colpaert, FC; Koek, W | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Akaike, N; Fukuda, A; Nakagawa, T; Shirasaki, T; Wakamori, M | 1 |
| Godfraind, JM | 1 |
| Iino, M; Ozawa, S; Tsuzuki, K | 1 |
| Bertolino, M; Vicini, S | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Alho, H; Barbaccia, ML; Costa, E; Szekely, AM | 1 |
| Salt, TE | 1 |
| Bauce, L; Kemp, DE; Weiss, S | 1 |
| Araneda, R; Bustos, G | 1 |
| Homma, S | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Davidson, N; Fong, TM; Lester, HA | 1 |
| Neal, M | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Hofmann, HD; Huba, R; Yamashita, M | 1 |
| Oja, SS; Saransaari, P | 3 |
| Bloms-Funke, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Matute, C; Miledi, R | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 2 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Francois-Bellan, AM; Giraud, P; Hery, F; Hery, M | 1 |
| Churn, SB; DeLorenzo, RJ; Limbrick, D; Sombati, S | 1 |
| Bonanno, G; Donadini, F; Fedele, E; Fontana, G; Raiteri, M; Vallebuona, F | 1 |
| Littman, L; Robinson, MB | 1 |
| Orrego, F; Riquelme, G; Villanueva, S; Wyneken, U | 2 |
| Biella, G; Lacerenza, M; Marchettini, P; Sotgiu, ML | 1 |
| Ishida, M; Kataoka, K; Nakamura, Y; Saitoh, T; Shinozaki, H; Tsuji, K | 1 |
| Burnett, JP; Kingston, AE; Lodge, D; Mayne, NG | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Choi, S; Lovinger, DM | 1 |
| Burke, JP; Hablitz, JJ | 1 |
| Sheardown, MJ; Thomsen, C | 1 |
| Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S | 1 |
| Buisson, A; Canzoniero, LM; Choi, DW; Sensi, SL; Yu, SP | 1 |
| Deng, A; Growdon, JH; Nitsch, RM; Wurtman, RJ | 1 |
| Deitmer, JW; Lohr, C | 1 |
| Rao, TS; Sacaan, AI; Santori, EM | 1 |
| Alger, BE; Kirov, SA; Morishita, W | 1 |
| Chu, Z; Hablitz, JJ | 2 |
| Blanc, EM; Guiramand, J; Jallageas, M; Recasens, M | 1 |
| Gao, C; Hu, HZ; Liu, S; Ren, J; Wood, JD; Xia, Y | 1 |
| Cooke, IM; Duan, S | 1 |
| Canonico, PL; Copani, A; de Grazia, U; Knöpfel, T; Nicoletti, F; Richelmi, P; Storto, M; Vairetti, M | 1 |
| Keele, NB; Neugebauer, V; Shinnick-Gallagher, P; Zinebi, F | 1 |
| Copani, A; Fisichella, G; Frati, C; Marchese, C; Nasca, MR; Nicoletti, F; Storto, M | 1 |
| Casabona, G; Copani, A; Di Giorgi Gerevini, V; Mutel, V; Nicoletti, F; Nicosia, A; Romano, C; Storto, M | 1 |
| Croucher, MJ; Harris, JR; Jane, DE; Thomas, LS | 1 |
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Battaglia, G; Bruno, V; Ceña, V; Cespédes, VM; Copani, A; Flor, PJ; Galindo, MF; Gasparini, F; Kuhn, R; Nicoletti, F; Sánchez-Prieto, J | 1 |
| Challiss, RA; McIlhinney, RA; Rhodes, A; Selkirk, JV | 1 |
| Foster, AC; Naeve, GS; Selkirk, JV | 1 |
| Ebert, B; Madsen, U; Vestergaard, HT; Vogensen, SB | 1 |
| Bridges, RJ; Nunn, PB; Patel, SA; Warren, BA | 1 |
| Eaton, MJ; Frydel, BR; Furst, C; Gómez-Marín, O; Hernandez, M; Huang, J; Martinez, M; Wolfe, SQ | 1 |
| Cumberbatch, N; Eaton, M; Martinez, M; Menendez, I; Quintero Wolfe, SC | 1 |
| Eaton, MJ; Wolfe, SQ | 1 |
| Beltramo, M; Brusa, R; Lozza, G; Mancini, I; Petrò, R; Reggiani, A; Scandroglio, P | 1 |
| Casoni, A; Clerici, F; Contini, A | 1 |
| Brown, EM; Conn, PJ; Hall, RA; Hamelberg, D; Jiang, JY; Meyer, RC; Nagaraju, M; Yang, JJ; Zhang, L | 1 |
1 review(s) available for quisqualic acid and glycine
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
87 other study(ies) available for quisqualic acid and glycine
| Article | Year |
|---|---|
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
Acoustic chiasm V: inhibition and excitation in the ipsilateral and contralateral projections of LSO.
Topics: Acoustic Stimulation; Animals; Auditory Perception; Brain Stem; Efferent Pathways; Functional Laterality; Glutamates; Glycine; Inferior Colliculi; Kainic Acid; Mammals; Models, Neurological; Olivary Nucleus; Quisqualic Acid; Receptors, AMPA; Receptors, GABA-A; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Neurotransmitter; Synapses | 1992 |
Selective potentiation of N-methyl-D-aspartate-induced current by protein kinase C in Xenopus oocytes injected with rat brain RNA.
Topics: Animals; Brain; Enzyme Activation; Glutamates; Glycine; Male; Membrane Potentials; N-Methylaspartate; Ovum; Protein Kinase C; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Tetradecanoylphorbol Acetate; Xenopus | 1992 |
Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Corpus Striatum; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Regulator; Glutamates; Glutamic Acid; Glycine; Immediate-Early Proteins; Isoquinolines; Neurons; Piperazines; Protein Kinase Inhibitors; Proto-Oncogenes; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Sulfonamides; Transcription Factors | 1992 |
Serotonin1A facilitation of frog motoneuron responses to afferent stimuli and to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Animals; Electric Stimulation; Evoked Potentials; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rana pipiens; Serotonin; Spinal Cord; Spinal Nerve Roots; Tetrahydronaphthalenes; Tetrodotoxin; Tropanes | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins | 1992 |
Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat.
Topics: Amino Acids; Animals; Brain Stem; Dose-Response Relationship, Drug; Electrophysiology; Enflurane; Flurothyl; gamma-Aminobutyric Acid; Glutamates; Glycine; Halothane; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter | 1991 |
Dual effect of glycine on isolated rat suprachiasmatic neurons.
Topics: Animals; Electrophysiology; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Strychnine; Suprachiasmatic Nucleus | 1991 |
Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead.
Topics: Animals; Aspartic Acid; Calcium; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Conductivity; Glycine; Hippocampus; Ion Channels; Kainic Acid; Lead; Learning Disabilities; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Modulation of the N-methyl-D-aspartate channel by extracellular H+.
Topics: Animals; Aspartic Acid; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Hydrogen-Ion Concentration; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Multiple effects of tetraethylammonium on N-methyl-D-aspartate receptor-channels in mouse brain neurons in cell culture.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Glycine; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Quisqualic Acid; Receptors, Cell Surface; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Capsaicin; Concanavalin A; Drug Tolerance; GABA Antagonists; Glycine; Injections, Spinal; Kainic Acid; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Substance P | 1991 |
Acoustic chiasm. III: Nature, distribution, and sources of afferents to the lateral superior olive in the cat.
Topics: Afferent Pathways; Animals; Auditory Pathways; Autoradiography; Axonal Transport; Carbon Radioisotopes; Cats; Deoxyglucose; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Olivary Nucleus; Quisqualic Acid; Receptors, AMPA; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Neurotransmitter; Tritium | 1991 |
Quisqualate activates N-methyl-D-aspartate receptor channels in hippocampal neurons maintained in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Electric Stimulation; Glycine; Hippocampus; Indoles; Ion Channel Gating; N-Methylaspartate; Neural Conduction; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
An electrophysiological study of the action of N-methyl-D-aspartate on excitatory synaptic transmission in the optic tectum of the frog in vitro.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electrophysiology; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rana temporaria; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Synapses; Synaptic Transmission | 1990 |
The correlation between excitatory amino acid-induced current responses and excitotoxicity in striatal cultures.
Topics: Animals; Cells, Cultured; Corpus Striatum; Glutamates; Glutamic Acid; Glycine; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
6,7-Dinitroquinoxaline-2,3-dione and 6-nitro,7-cyanoquinoxaline-2,3-dione antagonize responses mediated by N-methyl-D-aspartate and NMDA-associated glycine recognition sites in vivo: measurements of cerebellar cyclic-GMP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; Cyclic AMP; Glycine; Harmaline; Kinetics; Male; Mice; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Serine | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Synergism; Glycine; In Vitro Techniques; Indoles; Kainic Acid; Ketanserin; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropisetron | 1990 |
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; Kainic Acid; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Phencyclidine; Pyrrolidinones; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
Glutamate-receptor-mediated regulation of the cytoplasmic free calcium level in cultured cerebellar granule cells.
Topics: Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cytoplasm; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid response in isolated nucleus tractus solitarii neurons of the rat.
Topics: Amino Acids; Animals; Aspartic Acid; Electrophysiology; Glycine; In Vitro Techniques; Kainic Acid; Medulla Oblongata; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Microionophoretic study with milacemide, a glycine precursor, on mammalian central nervous system cells.
Topics: Acetamides; Animals; Aspartic Acid; Brain; Cats; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Kainic Acid; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid | 1990 |
Suppression by extracellular K+ of N-methyl-D-aspartate responses in cultured rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Cesium; Glycine; Hippocampus; Iontophoresis; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats | 1990 |
Voltage-dependent block by strychnine of N-methyl-D-aspartic acid-activated cationic channels in rat cortical neurons in culture.
Topics: Allosteric Regulation; Animals; Cations; Cells, Cultured; Cerebral Cortex; Drug Interactions; Glycine; Ion Channels; Kainic Acid; Magnesium; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1988 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.
Topics: Animals; Aspartic Acid; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Gene Expression Regulation; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Phencyclidine; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Transcription, Genetic | 1989 |
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo.
Topics: Action Potentials; Animals; Aspartic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine; Thalamus | 1989 |
Kainate evokes the release of endogenous glycine from striatal neurons in primary culture.
Topics: Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Modulation of dendritic release of dopamine by N-methyl-D-aspartate receptors in rat substantia nigra.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dendrites; Dopamine; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substantia Nigra; Tetrodotoxin | 1989 |
Effects of bath-applied excitatory amino acids and their analogs on spinal interneurons of the lamprey.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; Glycine; Homocysteine; In Vitro Techniques; Interneurons; Kainic Acid; Lampreys; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord | 1985 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus laevis | 1988 |
Transmitter interactions in the rabbit retina.
Topics: Acetylcholine; Animals; Aspartic Acid; Atropine; gamma-Aminobutyric Acid; Glutamates; Glycine; Kainic Acid; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Retina | 1983 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
Early in vitro development of voltage- and transmitter-gated currents in GABAergic amacrine cells.
Topics: Animals; Autoradiography; Cells, Cultured; Cellular Senescence; Chick Embryo; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Interneurons; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, GABA; Receptors, Glutamate; Retina; Time Factors; Tritium | 1994 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
Effects of the epileptogenic agent strychnine on membrane currents elicited by agonists of the NMDA and non-NMDA receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Glycine; Ion Channels; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Xenopus laevis | 1995 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Neurons; Quinoxalines; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Taurine; Tryptophan | 1993 |
Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Aggregation; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Glycine; Hippocampus; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kinetics; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Neurotoxins; Peptides; Phosphorylation; Potassium Chloride; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
(2S,1'R,2'R,3'R)-2-(2,3-dicarboxycyclopropyl) glycine positively modulates metabotropic glutamate receptors coupled to polyphosphoinositide hydrolysis in rat hippocampal slices.
Topics: Animals; Cyclopropanes; Glycine; Hippocampus; Hydrolysis; In Vitro Techniques; Phosphatidylinositol Phosphates; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Stimulation, Chemical | 1994 |
Heterocarrier-mediated reciprocal modulation of glutamate and glycine release in rat cerebral cortex and spinal cord synaptosomes.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium; Spinal Cord; Synaptosomes | 1994 |
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated.
Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
Regulation of D-aspartate release by glutamate and GABA receptors in cerebral cortical slices from developing and ageing mice.
Topics: Aging; Animals; Aspartic Acid; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Quisqualic Acid; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Taurine | 1994 |
Recordings of glutamate receptor channels in isolated postsynaptic densities.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamates; Glutamic Acid; Glycine; Histocytochemistry; In Vitro Techniques; Long-Term Potentiation; Neurotransmitter Agents; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Telencephalon | 1993 |
Diverse modulation by systemic lidocaine of iontophoretic NMDA and quisqualic acid induced excitations on rat dorsal horn neurons.
Topics: Animals; Drug Synergism; Glycine; Injections, Intravenous; Iontophoresis; Kynurenic Acid; Lidocaine; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine | 1993 |
Novel agonists for metabotropic glutamate receptors: trans- and cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- and cis-MCG-I).
Topics: Animals; Animals, Newborn; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reflex; Spinal Cord; Synapses | 1995 |
Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes.
Topics: Animals; Benzoates; Calcium; Cells, Cultured; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrolysis; Phosphatidylinositols; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1995 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Phenylglycines can evoke quisqualate-primed depolarizations in rat cingulate cortex: an effect associated with [3H]DL-AP4 uptake.
Topics: Aminobutyrates; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Gyrus Cinguli; Osmolar Concentration; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Tritium | 1996 |
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems | 1996 |
Effect of glutamate receptor phosphorylation by endogenous protein kinases on electrical activity of isolated postsynaptic densities of rat cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cerebral Cortex; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kainic Acid; Long-Term Potentiation; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses | 1997 |
Membrane-delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glycine; GTP-Binding Proteins; Membrane Potentials; Mice; Neuroglia; Neurons; Pregnancy; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1997 |
Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain.
Topics: Amyloid beta-Protein Precursor; Benzoates; Cell Line; Cycloleucine; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; GTP-Binding Proteins; Humans; Melitten; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Protein Kinases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Type C Phospholipases | 1997 |
Intracellular Ca2+ release mediated by metabotropic glutamate receptor activation in the leech giant glial cell.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Calcium-Transporting ATPases; Central Nervous System; Enzyme Inhibitors; Glutamic Acid; Glycine; Indoles; Intracellular Fluid; Ion Transport; Leeches; Ligands; Membrane Potentials; Neuroglia; Quisqualic Acid; Receptors, Metabotropic Glutamate | 1997 |
(S)-4-carboxy-3-hydroxyphenylglycine activates phosphatidyl inositol linked metabotropic glutamate receptors in different brain regions of the neonatal rat.
Topics: Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptosomes | 1998 |
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.
Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses | 1998 |
Activation of group I mGluRs increases spontaneous IPSC frequency in rat frontal cortex.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tetrodotoxin | 1998 |
Involvement of metabotropic glutamate receptors in taurine release in the adult and developing mouse hippocampus.
Topics: Age Factors; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Mice; Quisqualic Acid; Receptors, Metabotropic Glutamate; Taurine; Time Factors | 1999 |
Potentiation of glutamatergic agonist-induced inositol phosphate formation by basic fibroblast growth factor is related to developmental features in hippocampal cultures: neuronal survival and glial cell proliferation.
Topics: Animals; Antimetabolites, Antineoplastic; Benzoates; Cell Division; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloleucine; Cytarabine; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Fibroblast Growth Factor 2; Glutamic Acid; Glycine; Hippocampus; Inositol Phosphates; Neuroglia; Neurons; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Type C Phospholipases | 1999 |
Functional group I metabotropic glutamate receptors in submucous plexus of guinea-pig ileum.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Ileum; Male; Membrane Potentials; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Submucous Plexus | 1999 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Hypoxia; Cells, Cultured; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Immunohistochemistry; Liver; Male; Neuroprotective Agents; Pyridines; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kindling, Neurologic; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Phenylacetates; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Sodium; Tetrodotoxin; Up-Regulation | 2000 |
Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes.
Topics: Amino Acid Sequence; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glycine; Humans; Immunohistochemistry; Infant, Newborn; Male; Melanocytes; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphatidylinositol Phosphates; Pigmentation Disorders; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Skin; Sodium Glutamate; Tissue Extracts | 2000 |
Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.
Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Carbachol; Cell Membrane; Cerebellum; CHO Cells; Cholinergic Agonists; Colforsin; Cricetinae; Cyclic AMP; Cycloleucine; Cyclopropanes; Dimerization; Dithiothreitol; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Humans; Kidney; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 2000 |
Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.
Topics: Animals; Aspartic Acid; Autoreceptors; Benzoates; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Indans; Male; Neurons; Phenylacetates; Prosencephalon; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2000 |
Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Guanosine Diphosphate; In Vitro Techniques; Membrane Potentials; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Thionucleotides | 2000 |
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Mice; N-Methylaspartate; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Neurotoxins; Protein Kinase C; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2001 |
Characterization of an N-terminal secreted domain of the type-1 human metabotropic glutamate receptor produced by a mammalian cell line.
Topics: Amino Acid Sequence; Animals; Benzoates; Binding, Competitive; CHO Cells; Cricetinae; Dimerization; Excitatory Amino Acid Antagonists; Glycine; Glycoside Hydrolases; Glycosylation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Tritium | 2002 |
Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors.
Topics: Animals; Aspartic Acid; Benzoates; Colforsin; Cyclic AMP; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glycine; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Methoxyhydroxyphenylglycol; Pyridines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2003 |
Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.
Topics: Aminobutyrates; Animals; Calcium Chloride; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 2004 |
The Lathyrus excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-.
Topics: Amino Acid Transport System y+; Amino Acids, Diamino; Animals; Binding, Competitive; Cell Line, Tumor; Cyanobacteria Toxins; Cystine; Fluorometry; Glutamic Acid; Glycine; Humans; Kinetics; Neurotoxins; Quisqualic Acid; Rats; Receptors, Glutamate | 2004 |
Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Cell Line; Cell Transplantation; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glycine; Hot Temperature; Humans; Hyperalgesia; Immunohistochemistry; Male; Neurons; Pain; Pain Management; Pain Measurement; Phenotype; Quisqualic Acid; Rats; Rats, Inbred WF; Spinal Cord Injuries; Subarachnoid Space | 2007 |
Ronald Tasker Award: Intrathecal transplantation of a human neuronal cell line for the treatment of neuropathic pain in a spinal cord injury model.
Topics: Animals; Carcinoma, Embryonal; Cell Line, Tumor; gamma-Aminobutyric Acid; Glycine; Injections, Spinal; Male; Nerve Regeneration; Neuralgia; Neurons; Pain; Pain Threshold; Quisqualic Acid; Rats; Rats, Inbred WF; Spinal Cord; Spinal Cord Injuries; Vesicular Inhibitory Amino Acid Transport Proteins | 2007 |
Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats.
Topics: Animals; Behavior, Animal; Cell Line; Cell- and Tissue-Based Therapy; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glycine; Humans; Immunohistochemistry; Neuralgia; Neurons; Quisqualic Acid; Rats; Rats, Inbred WF; Spinal Cord; Spinal Cord Injuries | 2009 |
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.
Topics: Analgesics; Animals; Benzimidazoles; Biological Assay; Calcium; Cannabinoids; CHO Cells; Chromones; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Cycloleucine; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Naphthalenes; Neuroprotective Agents; Quinolines; Quisqualic Acid; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Thiazoles | 2010 |
Molecular dynamic simulation of mGluR5 amino terminal domain: essential dynamics analysis captures the agonist or antagonist behaviour of ligands.
Topics: Amino Acids; Binding Sites; Glutamic Acid; Glycine; Humans; Ligands; Molecular Dynamics Simulation; Phenylacetates; Principal Component Analysis; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Xanthenes | 2013 |
Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.
Topics: Allosteric Regulation; Amino Acid Substitution; Benzoates; Binding Sites; Calcium; Calcium Signaling; Carbamates; Excitatory Amino Acid Agonists; Glycine; HEK293 Cells; Humans; Mutation, Missense; Protein Structure, Tertiary; Quisqualic Acid; Receptors, Metabotropic Glutamate; Xanthenes | 2014 |