quinuclidines has been researched along with talsaclidine fumarate in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doods, HN; van Zwieten, PA | 1 |
| Doods, HN; Ensinger, HA; Immel-Sehr, AR; Kuhn, FJ; Lambrecht, G; Mendla, KD; Müller, RE; Mutschler, E; Sagrada, A; Walther, G | 1 |
| Burkard, S; Hammer, R; Palluk, R; Walland, A | 1 |
| Hammer, R; Walland, A | 1 |
| Pieper, MP; Walland, A | 1 |
| Bymaster, FP; Calligaro, DO; Carter, PA; DeLapp, N; Fink-Jensen, A; Jeppesen, L; Mitch, CH; Peters, SC; Rimvall, K; Sauerberg, P; Shannon, HE; Sheardown, MJ; Ward, JS; Whitesitt, CA; Zhang, W | 1 |
| Adamus, WS; Leonard, JP; Tröger, W | 1 |
| Greischel, A; Leusch, A; Roth, W; Tröger, W | 1 |
| Deng, M; Growdon, JH; Heuser, I; Hock, C; Maddalena, A; Naber, D; Nitsch, RM; Oertel, W; Raschig, A; von der Kammer, H; Wienrich, M | 1 |
| Ensinger, HA; Gaida, W; Hammer, R; Meier, D; Raschig, A; Walland, A; Wienrich, M | 1 |
| Borsini, F; Buccafusco, JJ; Leusch, A; Terry, AV | 1 |
| Eschweiler, G; Gonzalez-Agosti, C; Hager, K; Hampel, H; Heuser, I; Hock, C; Maddalena, A; Müller-Spahn, F; Müller-Thomsen, T; Nitsch, RM; Oertel, W; Raschig, A; Signorell, A; Wienrich, M | 1 |
| Schliebe, N; Schliebs, R; Zuchner, T | 1 |
1 review(s) available for quinuclidines and talsaclidine fumarate
| Article | Year |
|---|---|
Muscarinic receptors and drugs in cardiovascular medicine.
Topics: Bradycardia; Cardiovascular Diseases; Cholinergic Agents; Endothelium, Vascular; Humans; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Nitric Oxide; Parasympatholytics; Pirenzepine; Quinuclidines; Receptors, Muscarinic; Regression Analysis; Structure-Activity Relationship | 1995 |
3 trial(s) available for quinuclidines and talsaclidine fumarate
| Article | Year |
|---|---|
Phase I clinical trials with WAL 2014, a new muscarinic agonist for the treatment of Alzheimer's disease.
Topics: Administration, Oral; Adult; Alzheimer Disease; Blood Pressure; Brain; Dose-Response Relationship, Drug; Electroencephalography; Heart Rate; Humans; Male; Muscarinic Agonists; Quinuclidines; Receptor, Muscarinic M1; Receptors, Muscarinic; Salivation; Single-Blind Method | 1995 |
Treatment with the selective muscarinic agonist talsaclidine decreases cerebrospinal fluid levels of total amyloid beta-peptide in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Double-Blind Method; Humans; Muscarinic Agonists; Placebos; Quinuclidines | 2000 |
Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Peptide Fragments; Placebos; Quinuclidines; Receptor, Muscarinic M1 | 2003 |
9 other study(ies) available for quinuclidines and talsaclidine fumarate
| Article | Year |
|---|---|
WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties.
Topics: Animals; CHO Cells; Cricetinae; Decerebrate State; Dogs; Female; Guinea Pigs; Hemodynamics; Male; Neurons; Parasympathomimetics; Quinuclidines; Rabbits; Rats; Receptors, Muscarinic; Transfection | 1993 |
Compensation of muscarinic bronchial effects of talsaclidine by concomitant sympathetic activation in guinea pigs.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic beta-Antagonists; Animals; Arecoline; Bronchi; Bronchial Spasm; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Male; Muscarinic Agonists; Nicotinic Antagonists; Quinuclidines; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Spinal Cord; Sympathetic Nervous System | 1997 |
Muscarinic contraction in isolated guinea-pig trachea and antagonism by noradrenaline.
Topics: Animals; Bucladesine; Female; Guinea Pigs; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Contraction; Norepinephrine; Quinuclidines; Trachea | 1997 |
Central activation of the sympathetic nervous system including the adrenals in anaesthetized guinea pigs by the muscarinic agonist talsaclidine.
Topics: Adrenal Glands; Animals; Blood Pressure; Brain; Female; Guinea Pigs; Injections, Intravenous; Injections, Intraventricular; Ipratropium; Male; Muscarinic Agonists; Quinuclidines; Receptors, Muscarinic; Sympathetic Nervous System | 1998 |
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.
Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Cholinesterase Inhibitors; Dihydropyridines; Dose-Response Relationship, Drug; Hydrolysis; Hypothermia; Imines; Lithium; Male; Mice; Mice, Inbred Strains; Muscarinic Agonists; Oximes; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Pilocarpine; Pyridines; Quinuclidines; Radioligand Assay; Salivation; Tacrine; Tetrazoles; Thiadiazoles; Tremor | 1998 |
Pharmacokinetics of the M1-agonist talsaclidine in mouse, rat, rabbit and monkey, and extrapolation to man.
Topics: Alzheimer Disease; Animals; Blood Proteins; Carbon Radioisotopes; Female; Haplorhini; Humans; Kinetics; Male; Metabolic Clearance Rate; Mice; Muscarinic Agonists; Protein Binding; Quinuclidines; Rabbits; Rats; Species Specificity | 2000 |
Pharmacodynamic profile of the M1 agonist talsaclidine in animals and man.
Topics: Adrenergic beta-Antagonists; Adult; Alzheimer Disease; Animals; Bronchial Spasm; Dose-Response Relationship, Drug; Electroencephalography; Female; Guinea Pigs; Heart; Humans; Imines; In Vitro Techniques; Male; Middle Aged; Muscarinic Agonists; Muscle, Smooth; Neurons; Propanolamines; Quinuclidines; Rabbits; Rats; Receptors, Muscarinic | 2001 |
Memory-related task performance by aged rhesus monkeys administered the muscarinic M(1)-preferring agonist, talsaclidine.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Memory; Muscarinic Agonists; Psychomotor Performance; Quinuclidines; Receptor, Muscarinic M1; Receptors, Muscarinic; Time Factors | 2002 |
Zinc uptake is mediated by M1 muscarinic acetylcholine receptors in differentiated SK-SH-SY5Y cells.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Fluorescent Dyes; Gene Expression Regulation; Humans; Neuroblastoma; Nuclear Proteins; Protein Kinase C; Quinuclidines; Receptor, Muscarinic M1; RNA-Binding Proteins; Signal Transduction; Zinc; Zinc Fingers | 2006 |