Page last updated: 2024-08-18

quinuclidines and pumosetrag

quinuclidines has been researched along with pumosetrag in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blackshaw, E; Chan, PQ; Coleman, NS; Gowland, PA; Marciani, L; Parker, M; Perkins, AC; Spiller, RC; Wilde, K; Wright, J; Yamazaki, S; Yano, T1
Fujita, T; Kumagai, Y; Majima, M; Ohtani, Y; Sawada, M; Yokota, S1
Evangelista, S1
Chetty, N; Coupar, IM; Irving, HR1
Chai, W; Chan, KY; Danser, AH; de Maeyer, JH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schuurkes, JA; van den Bogeardt, AJ; Villalón, CM1
Choung, RS; Crowell, MD; Devault, K; Francis, DD; Harmsen, WS; Katzka, D; Locke, GR; Orr, WC; Talley, NJ; Winkle, PJ; Zinsmeister, AR1

Reviews

1 review(s) available for quinuclidines and pumosetrag

ArticleYear
Drug evaluation: Pumosetrag for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
    Current opinion in investigational drugs (London, England : 2000), 2007, Volume: 8, Issue:5

    Topics: Animals; Dopamine Agents; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Irritable Bowel Syndrome; Pyridines; Quinuclidines; Receptors, Serotonin, 5-HT3; Treatment Outcome

2007

Trials

3 trial(s) available for quinuclidines and pumosetrag

ArticleYear
Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans.
    Alimentary pharmacology & therapeutics, 2003, Nov-15, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Body Mass Index; Cross-Over Studies; Double-Blind Method; Gamma Cameras; Gastrointestinal Motility; Humans; Magnetic Resonance Imaging; Male; Manometry; Middle Aged; Pyridines; Quinuclidines; Radionuclide Imaging; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists; Stomach

2003
Effect of MKC-733, a 5-HT receptor partial agonist, on bowel motility and symptoms in subjects with constipation: an exploratory study.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:6

    Topics: Adult; Aged; Constipation; Defecation; Feces; Female; Gastrointestinal Motility; Humans; Male; Middle Aged; Pyridines; Quinuclidines; Serotonin Receptor Agonists

2005
Novel partial 5HT3 agonist pumosetrag reduces acid reflux events in uninvestigated GERD patients after a standard refluxogenic meal: a randomized, double-blind, placebo-controlled pharmacodynamic study.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Partial Agonism; Female; Gastroesophageal Reflux; Heartburn; Humans; Male; Meals; Middle Aged; Pyridines; Quinuclidines; Serotonin 5-HT3 Receptor Agonists; Young Adult

2014

Other Studies

2 other study(ies) available for quinuclidines and pumosetrag

ArticleYear
Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract.
    Pharmacology, 2008, Volume: 81, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Female; Gastrointestinal Tract; Guinea Pigs; Male; Mice; Pyridines; Quinuclidines; Rats; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists; Species Specificity

2008
Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae.
    Life sciences, 2012, Apr-09, Volume: 90, Issue:13-14

    Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Benzofurans; Calcium Channels; Child; Cisapride; Female; Gastrointestinal Agents; Heart Atria; Heart Ventricles; Humans; Indoles; Male; Middle Aged; Muscle Contraction; Myocardium; Pyridines; Quinuclidines; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Young Adult

2012