Compounds > quinuclidines
Page last updated: 2024-08-18

quinuclidines and pnu-282987

quinuclidines has been researched along with pnu-282987 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acker, BA; Fitzgerald, L; Groppi, VE; Hajos, M; Hoffmann, WE; Hurst, RS; Jacobsen, EJ; Krause, M; Li, KS; Myers, JK; Olson, BA; Piotrowski, DW; Raub, TJ; Reitz, SC; Rogers, BN; Staton, BA; Thornburgh, BA; Tinholt, PM; Walker, DP; Walters, RR; Wishka, DG; Wolfe, ML1
Atasoy, D; Lee, PH; Looger, LL; Magnus, CJ; Sternson, SM; Su, HH1
Altay, O; Duris, K; Krafft, PR; Lekic, T; Rolland, WB; Tang, J; Zhang, JH1
Bhyrapuneni, G; Kandikere, V; Komarneni, P; Muddana, N; Nirogi, R; Saralaya, R1
Hajós, M; Kelley, C; Leventhal, L; Nagy, D; Stoiljkovic, M1
Cecon, E; Chollet, AM; Dam, J; Danober, L; Delagrange, P; Gautier, C; Jockers, R; Luka, M1

Other Studies

6 other study(ies) available for quinuclidines and pnu-282987

ArticleYear
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.
    Bioorganic & medicinal chemistry letters, 2008, Jun-15, Volume: 18, Issue:12

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Azabicyclo Compounds; Benzamides; Blood Proteins; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Microsomes, Liver; Molecular Conformation; Nicotinic Agonists; Pyridines; Quinuclidines; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2008
Chemical and genetic engineering of selective ion channel-ligand interactions.
    Science (New York, N.Y.), 2011, Sep-02, Volume: 333, Issue:6047

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Brain; Bridged Bicyclo Compounds; Feeding Behavior; Female; HEK293 Cells; Humans; Ion Channel Gating; Ligand-Gated Ion Channels; Ligands; Membrane Potentials; Mice; Mice, Inbred C57BL; Mutagenesis; Neurons; Patch-Clamp Techniques; Protein Binding; Protein Engineering; Protein Structure, Tertiary; Quinuclidines; Receptors, Glycine; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Small Molecule Libraries; Stereoisomerism

2011
α7 nicotinic acetylcholine receptor agonism confers neuroprotection through GSK-3β inhibition in a mouse model of intracerebral hemorrhage.
    Stroke, 2012, Volume: 43, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Behavior, Animal; Benzamides; Blotting, Western; Body Water; Brain Chemistry; Brain Edema; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Caspase Inhibitors; Fluorescent Antibody Technique; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intracranial Hemorrhages; Male; Mice; Neurons; Neuroprotective Agents; Nicotinic Agonists; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinuclidines; Receptors, Nicotinic; Signal Transduction; Stroke; Treatment Outcome

2012
Methyllycaconitine: a non-radiolabeled ligand for mapping α7 neuronal nicotinic acetylcholine receptors - in vivo target localization and biodistribution in rat brain.
    Journal of pharmacological and toxicological methods, 2012, Volume: 66, Issue:1

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Benzofurans; Binding Sites; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Ligands; Male; Nicotinic Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic

2012
Selective activation of α7 nicotinic acetylcholine receptors augments hippocampal oscillations.
    Neuropharmacology, 2016, Volume: 110, Issue:Pt A

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Hippocampus; Male; Mice; Mice, Knockout; Nicotinic Agonists; Protein Binding; Quinuclidines; Theta Rhythm; Thiophenes

2016
Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor.
    British journal of pharmacology, 2019, Volume: 176, Issue:18

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; HEK293 Cells; Humans; Isoxazoles; Ligands; Phenylurea Compounds; Pyridines; Pyridinium Compounds; Quinuclidines; Thiophenes

2019