Compounds > quinuclidines
Page last updated: 2024-08-18

quinuclidines and isoxazoles

quinuclidines has been researched along with isoxazoles in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Begtrup, M; Christensen, B; Ehrbar, U; Hansen, JB; Olesen, PH; Pettersson, I; Rimvall, K; Tønder, JE1
Hara, T; Iwata, N; Kanek, T; Kondo, Y; Kozuka, M; Nagano, M; Niitsu, Y; Sakai, J; Sugimoto, M; Tonohiro, T; Yamamoto, T1
Ahring, PK; Anderson, DJ; Briggs, CA; Bunnelle, WH; Dyhring, T; Gopalakrishnan, M; Gopalakrishnan, S; Grønlien, JH; Gubbins, E; Håkerud, M; Helfrich, R; Hu, M; Ji, J; Li, J; Malysz, J; Meyer, MD; Nielsen, EØ; Peters, D; Puttfarcken, PS; Thorin-Hagene, K; Timmermann, DB; Ween, H1
Carroll, FI; Damaj, MI; Freitas, K; Negus, SS1
Bencherif, M; Budygin, E; Grinevich, V; Grinevich, VP; Gutkin, B; Maex, R1
Hao, Y; Tang, J; Wang, K1
Akbarali, HI; AlSharari, SD; Bagdas, D; Cabral, GA; Carroll, FI; Damaj, MI; Lichtman, PA; McGee, EA; Raborn, ES1
Biskup, E; Gniadecki, R; Naym, DG1
Dallanoce, C; Horenstein, NA; Matera, C; Papke, RL; Pismataro, MC; Quadri, M; Silnović, A; Stokes, C1
Bo, J; Gu, X; Hou, B; Huo, W; Lei, Y; Liu, Y; Liu, Z; Ma, Z; Mao, Y; Sun, R; Sun, Y; Zhang, W; Zhang, Y; Zhang, Z1
Cecon, E; Chollet, AM; Dam, J; Danober, L; Delagrange, P; Gautier, C; Jockers, R; Luka, M1

Other Studies

11 other study(ies) available for quinuclidines and isoxazoles

ArticleYear
Improving the nicotinic pharmacophore with a series of (Isoxazole)methylene-1-azacyclic compounds: synthesis, structure-activity relationship, and molecular modeling.
    Journal of medicinal chemistry, 1999, Dec-02, Volume: 42, Issue:24

    Topics: Animals; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Hydrogen Bonding; Isoxazoles; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Nicotine; Nitrogen; Quinuclidines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Static Electricity; Structure-Activity Relationship; Thermodynamics

1999
Activation of cerebral function by CS-932, a functionally selective M1 partial agonist: neurochemical characterization and pharmacological studies.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:3

    Topics: Animals; Binding, Competitive; Blood-Brain Barrier; Cerebral Cortex; CHO Cells; Cholinergic Agents; Cricetinae; Drug Antagonism; Electroencephalography; Hippocampus; Humans; In Vitro Techniques; Isoxazoles; Macaca fascicularis; Male; Memory, Short-Term; Mice; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nootropic Agents; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Saliva; Scopolamine; Sleep Stages

2000
In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
    The Journal of pharmacology and experimental therapeutics, 2010, Sep-01, Volume: 334, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Cell Line; Cells, Cultured; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Isoxazoles; Male; Nicotinic Agonists; Oocytes; Patch-Clamp Techniques; PC12 Cells; Phenylurea Compounds; Phosphorylation; Pyrroles; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substrate Specificity; Sulfonamides; Xenopus

2010
In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model.
    British journal of pharmacology, 2013, Volume: 169, Issue:3

    Topics: Acute Pain; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Behavior, Animal; Body Temperature Regulation; Bridged Bicyclo Compounds, Heterocyclic; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Isoxazoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Nicotine; Nicotinic Agonists; Nociceptive Pain; Pain Measurement; Phenylurea Compounds; Quinuclidines

2013
Understanding the role α7 nicotinic receptors play in dopamine efflux in nucleus accumbens.
    ACS chemical neuroscience, 2014, Oct-15, Volume: 5, Issue:10

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cerebral Cortex; Cholinergic Agents; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Isoxazoles; Male; Models, Neurological; Neural Pathways; Neurons; Nucleus Accumbens; Phenylurea Compounds; Quinuclidines; Rats, Sprague-Dawley; Synapses; Thiophenes

2014
Development of Automated Patch Clamp Assay for Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16.
    Assay and drug development technologies, 2015, Volume: 13, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Automation; Bridged Bicyclo Compounds; Humans; Indazoles; Isoxazoles; Nicotinic Agonists; Patch-Clamp Techniques; Phenylurea Compounds; Quinuclidines; Rats; Thiophenes; Tumor Cells, Cultured

2015
Sex Differences and Drug Dose Influence the Role of the α7 Nicotinic Acetylcholine Receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2017, Apr-01, Volume: 19, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bridged Bicyclo Compounds, Heterocyclic; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Isoxazoles; Male; Mice; Mice, Knockout; Phenylurea Compounds; Quinuclidines

2017
Small-molecule inhibitors of Ataxia Telangiectasia and Rad3 related kinase (ATR) sensitize lymphoma cells to UVA radiation.
    Journal of dermatological science, 2016, Volume: 84, Issue:3

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Flow Cytometry; Histones; Humans; Isoxazoles; Lymphoma, T-Cell, Cutaneous; Phosphorylation; Photochemotherapy; Photosensitizing Agents; Pyrazines; Quinolines; Quinuclidines; RNA, Small Interfering; Sulfones; Tumor Cells, Cultured; Ultraviolet Rays

2016
Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ
    ChemMedChem, 2017, 08-22, Volume: 12, Issue:16

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Drug Design; Humans; Isoxazoles; Nicotinic Agonists; Oocytes; Quinuclidines; Spiro Compounds; Structure-Activity Relationship; Xenopus laevis

2017
Perioperative activation of spinal α7 nAChR promotes recovery from preoperative stress-induced prolongation of postsurgical pain.
    Brain, behavior, and immunity, 2019, Volume: 79

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Anxiety; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Chronic Pain; Cytokines; Hyperalgesia; Isoxazoles; Male; Microglia; Nicotinic Agonists; Phenylurea Compounds; Preoperative Period; Quinuclidines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spine; Stress, Psychological

2019
Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor.
    British journal of pharmacology, 2019, Volume: 176, Issue:18

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; HEK293 Cells; Humans; Isoxazoles; Ligands; Phenylurea Compounds; Pyridines; Pyridinium Compounds; Quinuclidines; Thiophenes

2019