Page last updated: 2024-08-18

quinuclidines and darifenacin

quinuclidines has been researched along with darifenacin in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (3.45)	18.2507
2000's	20 (68.97)	29.6817
2010's	8 (27.59)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alabaster, VA	1
Honda, K; Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Takeuchi, M; Yamada, T	1
Ikeda, K; Kobayashi, S; Miyata, K	1
Hatanaka, T; Ikeda, K; Kobayashi, S; Miyata, K; Ohtake, A; Sasamata, M; Sato, S; Ukai, M	1
Hsieh, M; Kershen, RT	1
Sand, PK	1
Oehlke, KJ	1
Hussar, DA	1
MacDiarmid, SA; Staskin, DR	1
Hegde, SS; Michel, MC	1
Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H	1
Cardozo, L; Cartwright, R; Robinson, D; Vella, M	1
Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S	1
Hilas, O; Lam, S	1
Burcher, E; Chandran, JJ; Christopoulos, A; Mansfield, KJ; Millard, RJ; Mitchelson, FJ; Vaux, KJ	1
Ballarín, M; Balsa, D; Cabellos, J; Davalillo, S; Fernández, A; Lagunas, C; Pérez-Del-Pulgar, S; Salcedo, C	1
Brenes, FJ; Chapple, CR; Rosenberg, MT	1
Altman, D; Falconer, C; Granath, F; Mattiasson, A	1
Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A	1
Jakobsen, SM; Kersten, H; Molden, E	1
Bungay, PJ; Callegari, E; Fenner, KS; Kay, GG; Kempshall, S; LaPerle, JL; Malhotra, B; Michel, MC; Webster, R	1
Chess-Williams, R; Moro, C; Uchiyama, J	1
Kane, RL; Ramakrishnan, R; Sainfort, F; Shamliyan, T; Wyman, JF	1
Alessandri, F; Candiani, M; Ferrero, S; Leone Roberti Maggiore, U; Origoni, M; Remorgida, V; Salvatore, S; Venturini, PL	1
But, I; Goldstajn, MS; Oresković, S	1
Mauseth, SA; Skurtveit, S; Spigset, O	1

Reviews

11 review(s) available for quinuclidines and darifenacin

Article	Year
Discovery & development of selective M3 antagonists for clinical use. Life sciences, 1997, Volume: 60, Issue:13-14 Topics: Animals; Benzofurans; Dogs; Guinea Pigs; Humans; Lung Diseases, Obstructive; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Rabbits; Receptor, Muscarinic M3; Receptors, Muscarinic	1997
Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine. Current urology reports, 2004, Volume: 5, Issue:5 Topics: Benzilates; Benzofurans; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Muscarinic Antagonists; Nortropanes; Pyrrolidines; Quinuclidines; Selective Serotonin Reuptake Inhibitors; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Urinary Incontinence	2004
Elevating our therapeutic expectations in overactive bladder. Journal of the American Academy of Nurse Practitioners, 2004, Volume: 16, Issue:10 Suppl Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Constipation; Cresols; Delayed-Action Preparations; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Vision Disorders; Xerostomia	2004
Using anticholinergics to treat overactive bladder: the issue of treatment tolerability. The American journal of medicine, 2006, Volume: 119, Issue:3 Suppl 1 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cholinergic Antagonists; Cresols; Humans; Mandelic Acids; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence	2006
Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites? Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2006
New developments in the treatment of urinary incontinence. Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2006, Volume: 58, Issue:4 Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Benzofurans; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Mandelic Acids; Muscarinic Antagonists; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Stress	2006
Update on drugs for overactive bladder syndrome. Drug and therapeutics bulletin, 2007, Volume: 45, Issue:6 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cholinergic Antagonists; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2007
Pharmacologic management of overactive bladder. Clinical interventions in aging, 2007, Volume: 2, Issue:3 Topics: Benzhydryl Compounds; Benzofurans; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Overactive	2007
Listening to the patient: a flexible approach to the use of antimuscarinic agents in overactive bladder syndrome. BJU international, 2009, Volume: 104, Issue:7 Topics: Benzofurans; Drug Administration Schedule; Humans; Mandelic Acids; Multicenter Studies as Topic; Muscarinic Antagonists; Patient Satisfaction; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder, Overactive	2009
Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review. Annals of internal medicine, 2012, Jun-19, Volume: 156, Issue:12 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Comparative Effectiveness Research; Cresols; Female; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quality of Life; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence	2012
Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:11 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Chronic Disease; Cresols; Drug Combinations; Female; Humans; Imidazoles; Mandelic Acids; Muscarinic Antagonists; Nocturia; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive; Urinary Incontinence	2012

Trials

1 trial(s) available for quinuclidines and darifenacin

Article	Year
Comparison of two selective muscarinic receptor antagonists (solifenacin and darifenacin) in women with overactive bladder--the SOLIDAR study. Collegium antropologicum, 2012, Volume: 36, Issue:4 Topics: Benzofurans; Female; Humans; Middle Aged; Muscarinic Antagonists; Prospective Studies; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Treatment Outcome; Urinary Bladder, Overactive	2012

Article

Year

Comparison of two selective muscarinic receptor antagonists (solifenacin and darifenacin) in women with overactive bladder--the SOLIDAR study.

Collegium antropologicum, 2012, Volume: 36, Issue:4

Topics: Benzofurans; Female; Humans; Middle Aged; Muscarinic Antagonists; Prospective Studies; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Treatment Outcome; Urinary Bladder, Overactive

2012

Other Studies

17 other study(ies) available for quinuclidines and darifenacin

Article	Year
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2 Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mandelic Acids; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder	2002
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells. Life sciences, 2004, Jan-02, Volume: 74, Issue:7 Topics: Animals; Benzhydryl Compounds; Benzofurans; Calcium; Calcium Signaling; Carbachol; Cresols; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Macaca fascicularis; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2004
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats. European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3 Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Calcium; Cresols; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mandelic Acids; Muscarinic Antagonists; Myocytes, Smooth Muscle; Organ Specificity; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Wistar; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2004
Solifenacin and darifenacin for overactive bladder. The Medical letter on drugs and therapeutics, 2005, Mar-14, Volume: 47, Issue:1204 Topics: Benzofurans; Drug Interactions; Humans; Intestinal Obstruction; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Incontinence; Xerostomia	2005
New treatment options for overactive bladder. South Dakota journal of medicine, 2005, Volume: 58, Issue:6 Topics: Benzofurans; Clinical Trials as Topic; Humans; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Treatment Outcome; Urinary Incontinence	2005
Solifenacin and darifenacin for overactive bladder. Obstetrics and gynecology, 2005, Volume: 106, Issue:2 Topics: Benzofurans; Drug Interactions; Humans; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder Diseases; Urinary Incontinence	2005
New drugs 06, part I. Nursing, 2006, Volume: 36, Issue:2 Topics: Acamprosate; Adenine Nucleotides; Alcohol Deterrents; Amyloid; Analgesics, Non-Narcotic; Anti-HIV Agents; Antifungal Agents; Antineoplastic Agents; Aptamers, Nucleotide; Arabinonucleosides; Azabicyclo Compounds; Benzofurans; Clofarabine; Drug Approval; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Echinocandins; Exenatide; Fibroblast Growth Factor 7; Guanine; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lipopeptides; Lipoproteins; Macular Degeneration; Micafungin; omega-Conotoxins; Patient Education as Topic; Peptides; Peptides, Cyclic; Piperazines; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Stomatitis; Taurine; Tetrahydroisoquinolines; Urinary Incontinence; Venoms	2006
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1 Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination	2007
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model. European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3 Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; Injections, Intra-Arterial; Male; Mandelic Acids; Phenylpropanolamine; Pressure; Pyrrolidines; Quinuclidines; Rabbits; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2007
Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3 Topics: Aged; Benzhydryl Compounds; Benzofurans; Cresols; Cystectomy; Female; Humans; Male; Middle Aged; Mucous Membrane; Muscarinic Antagonists; Phenylpropanolamine; Prostatectomy; Pyrrolidines; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urinary Bladder, Overactive	2009
In vivo and in vitro pharmacological characterization of SVT-40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder. British journal of pharmacology, 2009, Volume: 156, Issue:5 Topics: Animals; Atrial Function; Benzhydryl Compounds; Benzofurans; Carbamates; Cresols; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2009
Anticholinergic drug use for overactive bladder in Sweden: a nationwide pharmacoepidemiological study. International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:11 Topics: Benzhydryl Compounds; Benzofurans; Cholinergic Antagonists; Cresols; Female; Health Care Costs; Humans; Muscarinic Antagonists; Pharmacoepidemiology; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Registries; Retrospective Studies; Solifenacin Succinate; Sweden; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2009
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. Urology, 2010, Volume: 76, Issue:4 Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Models, Animal; Down-Regulation; Female; Hydrochloric Acid; Mandelic Acids; N-Methylscopolamine; Organophosphonates; Phenols; Phenylpropanolamine; Pirenzepine; Polycyclic Compounds; Pyridoxal Phosphate; Pyrrolidines; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urination; Urodynamics	2010
Evaluation of brain anticholinergic activities of urinary spasmolytic drugs using a high-throughput radio receptor bioassay. Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:3 Topics: Benzhydryl Compounds; Benzofurans; Biological Assay; Brain; Cognition Disorders; Cresols; Humans; In Vitro Techniques; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate	2011
A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder. British journal of clinical pharmacology, 2011, Volume: 72, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzhydryl Compounds; Benzofurans; Blood-Brain Barrier; Brain; Cell Line; Chromatography, High Pressure Liquid; Cresols; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Solifenacin Succinate; Tandem Mass Spectrometry; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2011
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol. Urology, 2011, Volume: 78, Issue:6 Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium	2011
Adherence, persistence and switch rates for anticholinergic drugs used for overactive bladder in women: data from the Norwegian Prescription Database. Acta obstetricia et gynecologica Scandinavica, 2013, Volume: 92, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Benzofurans; Cholinergic Antagonists; Cresols; Databases, Pharmaceutical; Drug Substitution; Female; Follow-Up Studies; Humans; Medication Adherence; Middle Aged; Norway; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive; Young Adult	2013