Page last updated: 2024-08-18

quinuclidines and benzofurans

quinuclidines has been researched along with benzofurans in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (4.65)	18.2507
2000's	23 (53.49)	29.6817
2010's	16 (37.21)	24.3611
2020's	2 (4.65)	2.80

Authors

Authors	Studies
Glas, G; Hacksell, U; Johansson, G; Nilvebrant, L; Nordvall, G; Sundquist, S	1
Alabaster, VA	1
Honda, K; Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Takeuchi, M; Yamada, T	1
Ikeda, K; Kobayashi, S; Miyata, K	1
Hatanaka, T; Ikeda, K; Kobayashi, S; Miyata, K; Ohtake, A; Sasamata, M; Sato, S; Ukai, M	1
Hsieh, M; Kershen, RT	1
Sand, PK	1
Oehlke, KJ	1
Hussar, DA	1
MacDiarmid, SA; Staskin, DR	1
Hegde, SS; Michel, MC	1
Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H	1
Cardozo, L; Cartwright, R; Robinson, D; Vella, M	1
Boess, FG; De Vry, J; Erb, C; Flessner, T; Hendrix, M; Koenig, G; Luithle, J; Methfessel, C; Riedl, B; Schnizler, K; van der Staay, FJ; van Kampen, M; Wiese, WB	1
Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S	1
Hilas, O; Lam, S	1
Billinton, A; Bingham, S; Chessell, IP; Clayton, NM; Hatcher, JP; Hille, CJ; Medhurst, SJ	1
Burcher, E; Chandran, JJ; Christopoulos, A; Mansfield, KJ; Millard, RJ; Mitchelson, FJ; Vaux, KJ	1
Ballarín, M; Balsa, D; Cabellos, J; Davalillo, S; Fernández, A; Lagunas, C; Pérez-Del-Pulgar, S; Salcedo, C	1
Brenes, FJ; Chapple, CR; Rosenberg, MT	1
Bencherif, M; Gatto, GJ; Hauser, TA; Hesse, RA; Jordan, KG; Kucinski, A; Lippiello, PM; Papke, RL; Stachowiak, EK; Stachowiak, MK; Wersinger, SR	1
Altman, D; Falconer, C; Granath, F; Mattiasson, A	1
Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A	1
Jakobsen, SM; Kersten, H; Molden, E	1
Bungay, PJ; Callegari, E; Fenner, KS; Kay, GG; Kempshall, S; LaPerle, JL; Malhotra, B; Michel, MC; Webster, R	1
Chess-Williams, R; Moro, C; Uchiyama, J	1
Chai, W; Chan, KY; Danser, AH; de Maeyer, JH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schuurkes, JA; van den Bogeardt, AJ; Villalón, CM	1
Bhyrapuneni, G; Kandikere, V; Komarneni, P; Muddana, N; Nirogi, R; Saralaya, R	1
Kane, RL; Ramakrishnan, R; Sainfort, F; Shamliyan, T; Wyman, JF	1
Alessandri, F; Candiani, M; Ferrero, S; Leone Roberti Maggiore, U; Origoni, M; Remorgida, V; Salvatore, S; Venturini, PL	1
Benson, L; Dull, G; Fedorov, NB; Genus, JF; Hammond, PS; Hauser, TA; James, JW; Kombo, DC; Mazurov, AA; Miao, L; Miller, CH; Sidach, S; Xiao, Y; Yohannes, D	1
Beaver, JS; Duan, N; Dunbar, G; Girgis, RR; Hosford, DA; Lieberman, JA; Segreti, AC; Seoane, F	1
But, I; Goldstajn, MS; Oresković, S	1
Mauseth, SA; Skurtveit, S; Spigset, O	1
Camilleri, M; Erwin, P; Kolar, G; Murad, MH; Shin, A; West, CP	1
Parachikova, AI; Pedersen, CS; Plath, N; Sørensen, DB	1
Beaver, JS; Dunbar, GC; Dvergsten, C; Fleischhacker, WW; Hosford, DA; Jett, JE; Kane, J; Keefe, RS; Marder, SR; Segreti, AC; Toler, SM; Walling, D	1
Bornstein, JC; Gwynne, RM	1
Canning, BJ; DeVita, R; Dicpinigaitis, PV; Hay, DW; Liang, J; Liu, Q; Perelman, M; Tao, M	1
Wang, M; Zhang, W; Zhang, Z	1

Reviews

13 review(s) available for quinuclidines and benzofurans

Article	Year
Discovery & development of selective M3 antagonists for clinical use. Life sciences, 1997, Volume: 60, Issue:13-14 Topics: Animals; Benzofurans; Dogs; Guinea Pigs; Humans; Lung Diseases, Obstructive; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Rabbits; Receptor, Muscarinic M3; Receptors, Muscarinic	1997
Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine. Current urology reports, 2004, Volume: 5, Issue:5 Topics: Benzilates; Benzofurans; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Muscarinic Antagonists; Nortropanes; Pyrrolidines; Quinuclidines; Selective Serotonin Reuptake Inhibitors; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Urinary Incontinence	2004
Elevating our therapeutic expectations in overactive bladder. Journal of the American Academy of Nurse Practitioners, 2004, Volume: 16, Issue:10 Suppl Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Constipation; Cresols; Delayed-Action Preparations; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Vision Disorders; Xerostomia	2004
Using anticholinergics to treat overactive bladder: the issue of treatment tolerability. The American journal of medicine, 2006, Volume: 119, Issue:3 Suppl 1 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cholinergic Antagonists; Cresols; Humans; Mandelic Acids; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence	2006
Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites? Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2006
New developments in the treatment of urinary incontinence. Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2006, Volume: 58, Issue:4 Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Benzofurans; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Mandelic Acids; Muscarinic Antagonists; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Stress	2006
Update on drugs for overactive bladder syndrome. Drug and therapeutics bulletin, 2007, Volume: 45, Issue:6 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cholinergic Antagonists; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2007
Pharmacologic management of overactive bladder. Clinical interventions in aging, 2007, Volume: 2, Issue:3 Topics: Benzhydryl Compounds; Benzofurans; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Overactive	2007
Listening to the patient: a flexible approach to the use of antimuscarinic agents in overactive bladder syndrome. BJU international, 2009, Volume: 104, Issue:7 Topics: Benzofurans; Drug Administration Schedule; Humans; Mandelic Acids; Multicenter Studies as Topic; Muscarinic Antagonists; Patient Satisfaction; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder, Overactive	2009
Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review. Annals of internal medicine, 2012, Jun-19, Volume: 156, Issue:12 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Comparative Effectiveness Research; Cresols; Female; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quality of Life; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence	2012
Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:11 Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Chronic Disease; Cresols; Drug Combinations; Female; Humans; Imidazoles; Mandelic Acids; Muscarinic Antagonists; Nocturia; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive; Urinary Incontinence	2012
Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:3 Topics: Adult; Azabicyclo Compounds; Benzamides; Benzofurans; Chronic Disease; Constipation; Defecation; Humans; Polyethylene Glycols; Quality of Life; Quinuclidines; Serotonin 5-HT4 Receptor Agonists	2014
Luminal 5-HT Neurogastroenterology and motility, 2019, Volume: 31, Issue:10 Topics: Azabicyclo Compounds; Benzamides; Benzofurans; Colon; Constipation; Gastrointestinal Motility; Humans; Intestinal Mucosa; Laxatives; Molecular Targeted Therapy; Pyrimidines; Quinuclidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists	2019

Trials

3 trial(s) available for quinuclidines and benzofurans

Article	Year
A randomized exploratory trial of an α-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:6 Topics: Adolescent; Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Benzofurans; Female; Humans; India; Male; Middle Aged; Nicotinic Agonists; Nootropic Agents; Quinuclidines; Schizophrenia; Schizophrenic Psychology; United States; Young Adult	2013
Comparison of two selective muscarinic receptor antagonists (solifenacin and darifenacin) in women with overactive bladder--the SOLIDAR study. Collegium antropologicum, 2012, Volume: 36, Issue:4 Topics: Benzofurans; Female; Humans; Middle Aged; Muscarinic Antagonists; Prospective Studies; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Treatment Outcome; Urinary Bladder, Overactive	2012
Phase 2 Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) in Negative and Cognitive Symptoms of Schizophrenia. Schizophrenia bulletin, 2016, Volume: 42, Issue:2 Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Benzofurans; Female; Humans; Male; Middle Aged; Nicotinic Agonists; Outcome Assessment, Health Care; Quinuclidines; Schizophrenia; Severity of Illness Index; Young Adult	2016

Other Studies

27 other study(ies) available for quinuclidines and benzofurans

Article	Year
3-(2-Benzofuranyl)quinuclidin-2-ene derivatives: novel muscarinic antagonists. Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17 Topics: Amino Acid Sequence; Animals; Benzofurans; Binding, Competitive; Cerebral Cortex; Cholinergic Agents; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Models, Molecular; Molecular Sequence Data; Molecular Structure; Muscarinic Antagonists; Muscle, Smooth; Organ Specificity; Protein Conformation; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Structure-Activity Relationship; Urinary Bladder	1996
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2 Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mandelic Acids; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder	2002
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells. Life sciences, 2004, Jan-02, Volume: 74, Issue:7 Topics: Animals; Benzhydryl Compounds; Benzofurans; Calcium; Calcium Signaling; Carbachol; Cresols; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Macaca fascicularis; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2004
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats. European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3 Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Calcium; Cresols; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mandelic Acids; Muscarinic Antagonists; Myocytes, Smooth Muscle; Organ Specificity; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Wistar; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2004
Solifenacin and darifenacin for overactive bladder. The Medical letter on drugs and therapeutics, 2005, Mar-14, Volume: 47, Issue:1204 Topics: Benzofurans; Drug Interactions; Humans; Intestinal Obstruction; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Incontinence; Xerostomia	2005
New treatment options for overactive bladder. South Dakota journal of medicine, 2005, Volume: 58, Issue:6 Topics: Benzofurans; Clinical Trials as Topic; Humans; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Treatment Outcome; Urinary Incontinence	2005
Solifenacin and darifenacin for overactive bladder. Obstetrics and gynecology, 2005, Volume: 106, Issue:2 Topics: Benzofurans; Drug Interactions; Humans; Muscarinic Antagonists; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder Diseases; Urinary Incontinence	2005
New drugs 06, part I. Nursing, 2006, Volume: 36, Issue:2 Topics: Acamprosate; Adenine Nucleotides; Alcohol Deterrents; Amyloid; Analgesics, Non-Narcotic; Anti-HIV Agents; Antifungal Agents; Antineoplastic Agents; Aptamers, Nucleotide; Arabinonucleosides; Azabicyclo Compounds; Benzofurans; Clofarabine; Drug Approval; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Echinocandins; Exenatide; Fibroblast Growth Factor 7; Guanine; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lipopeptides; Lipoproteins; Macular Degeneration; Micafungin; omega-Conotoxins; Patient Education as Topic; Peptides; Peptides, Cyclic; Piperazines; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Stomatitis; Taurine; Tetrahydroisoquinolines; Urinary Incontinence; Venoms	2006
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1 Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination	2007
The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:2 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Cognition Disorders; Exploratory Behavior; Generalization, Psychological; Male; Maze Learning; Memory; Mice; Nicotinic Agonists; Quinuclidines; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Wistar; Receptors, Nicotinic	2007
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model. European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3 Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; Injections, Intra-Arterial; Male; Mandelic Acids; Phenylpropanolamine; Pressure; Pyrrolidines; Quinuclidines; Rabbits; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2007
Activation of the alpha7-nicotinic acetylcholine receptor reverses complete freund adjuvant-induced mechanical hyperalgesia in the rat via a central site of action. The journal of pain, 2008, Volume: 9, Issue:7 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzofurans; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Animal; Nicotinic Antagonists; Pain; Pain Measurement; Quinuclidines; Rats; Receptors, Nicotinic; Weight-Bearing	2008
Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3 Topics: Aged; Benzhydryl Compounds; Benzofurans; Cresols; Cystectomy; Female; Humans; Male; Middle Aged; Mucous Membrane; Muscarinic Antagonists; Phenylpropanolamine; Prostatectomy; Pyrrolidines; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urinary Bladder, Overactive	2009
In vivo and in vitro pharmacological characterization of SVT-40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder. British journal of pharmacology, 2009, Volume: 156, Issue:5 Topics: Animals; Atrial Function; Benzhydryl Compounds; Benzofurans; Carbamates; Cresols; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder	2009
TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia. Biochemical pharmacology, 2009, Oct-01, Volume: 78, Issue:7 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Clozapine; Cognition Disorders; Exploratory Behavior; Female; Male; Maze Learning; Mice; Mice, Transgenic; Neurons; Nicotinic Agonists; Promoter Regions, Genetic; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Nicotinic; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Social Behavior; Tyrosine 3-Monooxygenase	2009
Anticholinergic drug use for overactive bladder in Sweden: a nationwide pharmacoepidemiological study. International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:11 Topics: Benzhydryl Compounds; Benzofurans; Cholinergic Antagonists; Cresols; Female; Health Care Costs; Humans; Muscarinic Antagonists; Pharmacoepidemiology; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Registries; Retrospective Studies; Solifenacin Succinate; Sweden; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2009
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. Urology, 2010, Volume: 76, Issue:4 Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Models, Animal; Down-Regulation; Female; Hydrochloric Acid; Mandelic Acids; N-Methylscopolamine; Organophosphonates; Phenols; Phenylpropanolamine; Pirenzepine; Polycyclic Compounds; Pyridoxal Phosphate; Pyrrolidines; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urination; Urodynamics	2010
Evaluation of brain anticholinergic activities of urinary spasmolytic drugs using a high-throughput radio receptor bioassay. Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:3 Topics: Benzhydryl Compounds; Benzofurans; Biological Assay; Brain; Cognition Disorders; Cresols; Humans; In Vitro Techniques; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate	2011
A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder. British journal of clinical pharmacology, 2011, Volume: 72, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzhydryl Compounds; Benzofurans; Blood-Brain Barrier; Brain; Cell Line; Chromatography, High Pressure Liquid; Cresols; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Solifenacin Succinate; Tandem Mass Spectrometry; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive	2011
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol. Urology, 2011, Volume: 78, Issue:6 Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium	2011
Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae. Life sciences, 2012, Apr-09, Volume: 90, Issue:13-14 Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Benzofurans; Calcium Channels; Child; Cisapride; Female; Gastrointestinal Agents; Heart Atria; Heart Ventricles; Humans; Indoles; Male; Middle Aged; Muscle Contraction; Myocardium; Pyridines; Quinuclidines; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Young Adult	2012
Methyllycaconitine: a non-radiolabeled ligand for mapping α7 neuronal nicotinic acetylcholine receptors - in vivo target localization and biodistribution in rat brain. Journal of pharmacological and toxicological methods, 2012, Volume: 66, Issue:1 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Benzofurans; Binding Sites; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Ligands; Male; Nicotinic Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic	2012
Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a selective α7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzofurans; CHO Cells; Cognition Disorders; Cricetinae; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Models, Molecular; Molecular Structure; Quinuclidines; Rats; Receptors, Nicotinic; Structure-Activity Relationship	2012
Adherence, persistence and switch rates for anticholinergic drugs used for overactive bladder in women: data from the Norwegian Prescription Database. Acta obstetricia et gynecologica Scandinavica, 2013, Volume: 92, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Benzofurans; Cholinergic Antagonists; Cresols; Databases, Pharmaceutical; Drug Substitution; Female; Follow-Up Studies; Humans; Medication Adherence; Middle Aged; Norway; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive; Young Adult	2013
PCP-induced deficits in murine nest building activity: employment of an ethological rodent behavior to mimic negative-like symptoms of schizophrenia. Behavioural brain research, 2014, Oct-15, Volume: 273 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Quinuclidines; Rotarod Performance Test; Schizophrenia; Schizophrenic Psychology; Social Behavior; Thiophenes	2014
Evidence for Alpha The Journal of pharmacology and experimental therapeutics, 2022, Volume: 380, Issue:2 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antitussive Agents; Benzofurans; Cough; Guinea Pigs; Male; Nicotine; Nicotinic Agonists; Quinuclidines	2022
Design, Synthesis, and Application of Chiral Bicyclic Imidazole Catalysts. Accounts of chemical research, 2022, 09-20, Volume: 55, Issue:18 Topics: Acrolein; Amidines; Amines; Benzofurans; Carbamates; Catalysis; Imidazoles; Lactams; Lewis Bases; Oxindoles; Pyridines; Quinuclidines; Stereoisomerism	2022