Page last updated: 2024-08-17

quinoxalines and zk 200775

quinoxalines has been researched along with zk 200775 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Dirnagl, U; Huth, A; Jacobsen, P; McDonald, F; Neuhaus, R; Ottow, E; Schneider, HH; Sheardown, M; Turski, L; Wiegand, F1
Groom, A; Smith, T; Turski, L; Zhu, B1
De Keyser, J; Diener, HC; Elting, JW; Hommel, M; Kaste, M; Lees, KR; Sulter, GA; Teelken, AW; Versavel, M1
Cebere, A; Cebers, G; Kosowski, AR; Liljequist, S; Swanhagen, AC1
De Keyser, J; Diener, HC; Hommel, M; Kaste, M; Lees, KR; Steiner, H; Versavel, M; Walters, MR1
Gronier, B1
Bergholz, R; Rüther, K; Staks, T1
Ikemoto, S; Jhou, TC; Shin, R; Vollrath-Smith, FR; Webb, SM; Xu, S1
Li, M; Sobolevsky, AI; Yelshanskaya, MV1
Boesen, T; Dorosz, J; Gajhede, M; Kastrup, JS; Krintel, C; Larsen, AH; Mirza, O; Thorsen, TS; Venskutonytė, R1

Trials

3 trial(s) available for quinoxalines and zk 200775

ArticleYear
AMPA antagonist ZK200775 in patients with acute ischemic stroke: possible glial cell toxicity detected by monitoring of S-100B serum levels.
    Stroke, 2002, Volume: 33, Issue:12

    Topics: Acute Disease; Aged; Area Under Curve; Biomarkers; Brain Ischemia; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Nerve Growth Factors; Neuroglia; Organophosphonates; Phosphopyruvate Hydratase; Quinoxalines; Receptors, AMPA; Regression Analysis; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Severity of Illness Index; Stroke; Treatment Outcome

2002
The AMPA antagonist ZK 200775 in patients with acute ischaemic stroke: a double-blind, multicentre, placebo-controlled safety and tolerability study.
    Cerebrovascular diseases (Basel, Switzerland), 2005, Volume: 20, Issue:5

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; Electrocardiography; Humans; Middle Aged; Organophosphonates; Patient Compliance; Quinoxalines; Receptors, AMPA; Stroke; Treatment Outcome

2005
Effects of the AMPA antagonist ZK 200775 on visual function: a randomized controlled trial.
    PloS one, 2010, Aug-12, Volume: 5, Issue:8

    Topics: Aged; Color Vision; Darkness; Electroretinography; Evoked Potentials, Visual; Humans; Male; Middle Aged; Organophosphonates; Quinoxalines; Receptors, AMPA; Vision, Ocular; Visual Acuity

2010

Other Studies

7 other study(ies) available for quinoxalines and zk 200775

ArticleYear
ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-01, Volume: 95, Issue:18

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebrovascular Disorders; Craniocerebral Trauma; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; In Vitro Techniques; Mice; Neuroprotective Agents; Organophosphonates; Quinoxalines; Radioligand Assay; Rats

1998
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
    Nature medicine, 2000, Volume: 6, Issue:1

    Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Neurons; Multiple Sclerosis; Muscle Tonus; Myelin Basic Protein; Neurons; Organophosphonates; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; Receptors, Kainic Acid; Recurrence; Spinal Cord; T-Lymphocytes

2000
Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551.
    Psychopharmacology, 2004, Volume: 175, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dopamine; Male; Microdialysis; Motor Activity; Nicotine; Nucleus Accumbens; Organophosphonates; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Time Factors

2004
Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat.
    Neuroscience, 2008, Oct-28, Volume: 156, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; Glutamic Acid; Male; Neurons; Organophosphonates; Piperazines; Prefrontal Cortex; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Ventral Tegmental Area

2008
Rewarding and incentive motivational effects of excitatory amino acid receptor antagonists into the median raphe and adjacent regions of the rat.
    Psychopharmacology, 2012, Volume: 224, Issue:3

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Light; Male; Motivation; Motor Activity; Organophosphonates; Photic Stimulation; Pons; Quinoxalines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration; Time Factors; Vision, Ocular

2012
Structure of an agonist-bound ionotropic glutamate receptor.
    Science (New York, N.Y.), 2014, Aug-29, Volume: 345, Issue:6200

    Topics: Animals; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Models, Chemical; Organophosphonates; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA

2014
Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.
    The FEBS journal, 2021, Volume: 288, Issue:3

    Topics: Allosteric Regulation; Animals; Benzodiazepines; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Organophosphonates; Protein Binding; Protein Domains; Quinoxalines; Rats; Receptors, AMPA; Recombinant Proteins; Sf9 Cells; Spodoptera

2021