quinoxalines has been researched along with zaprinast in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (29.03) | 18.2507 |
| 2000's | 20 (64.52) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coste, H; Grondin, P | 1 |
| Anwyl, R; Rowan, MJ; Wang, Y; Wu, J | 1 |
| Ruiz, E; Tejerina, T | 1 |
| Cellek, S; Moncada, S | 1 |
| Cohen, RA; Griswold, MC; Komalavilas, P; Lincoln, TM; Weisbrod, RM; Yaghoubi, M | 1 |
| Allescher, HD; Fritsch, R; Kurjak, M; Saur, D; Schusdziarra, V | 1 |
| D'Angelo, S; Mulè, F; Serio, R | 1 |
| Gibson, A; O'Kane, K | 1 |
| Gong, GX; Scholz, PM; Straznicka, M; Tse, J; Weiss, HR; Yan, L | 1 |
| Fung, HL; Tabrizi-Fard, MA; Tseng, CM | 1 |
| Costa, G; García-Pascual, A; Jiménez, E; Labadía, A; Triguero, D | 1 |
| Huang, MW; Scholz, PM; Weiss, HR; Yan, L | 1 |
| Johns, RA; Li, D; Shirakami, G; Zhan, X | 1 |
| Gustafsson, LE; Hallén, K; Olgart, C; Wiklund, NP | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Russo, I; Trovati, M | 1 |
| Edvinsson, L; Jansen-Olesen, I; Khurana, TS; Kruuse, C; Olesen, J; Rybalkin, SD | 1 |
| Boon, K; Fooks, HM; Hourani, SM; Prentice, DJ | 1 |
| Allescher, HD; Folmer, R; Kurjak, M; Schusdziarra, V; Storr, M | 1 |
| Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ | 1 |
| Fujimoto, S; Mori, M; Tsushima, H | 1 |
| Kankuri, E; Kotikoski, H; Vapaatalo, H | 1 |
| Cao, J; Inoue, M; Kitazawa, T; Taneike, T | 1 |
| Ozdem, SS; Sadan, G; Tasatargil, A | 1 |
| Chung, E; Li, S; Quock, RM | 1 |
| Anctil, M; Pelletier, C; Poulain, I | 1 |
| Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
| Eltze, M; Grebe, T; Hatzelmann, A; Klein, T; Kömhoff, M | 1 |
| Edwards, TM; Lindley, N | 1 |
| Bellas, E; Bloch, KD; Buys, ES; Evgenov, NV; Evgenov, OV; Gnoth, MJ; Graveline, AR; Hess, DR; Kohane, DS; Langer, R; Liu, R; Stasch, JP; Volpato, GP; Zapol, WM | 1 |
| Blouquit-Laye, S; Braun, C; Chinet, T; Dannhoffer, L; Dinh-Xuan, AT; Sage, E | 1 |
| Chen, Z; Dou, D; Gao, Y; Liu, H; Liu, J; Liu, L; Ye, L; Yu, X | 1 |
31 other study(ies) available for quinoxalines and zaprinast
| Article | Year |
|---|---|
Characterization of a novel potent and specific inhibitor of type V phosphodiesterase.
Topics: Allopurinol; Animals; Atrial Natriuretic Factor; Cattle; Cyclic AMP; Cyclic GMP; Imidazoles; Isoenzymes; Muscle, Smooth, Vascular; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Quinoxalines; Rats; Sensitivity and Specificity; Stimulation, Chemical | 1995 |
Evidence for involvement of the cGMP-protein kinase G signaling system in the induction of long-term depression, but not long-term potentiation, in the dentate gyrus in vitro.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Alkaloids; Animals; Benzoates; Carbazoles; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Long-Term Potentiation; Neurons; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinases; Purinones; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1998 |
Relaxant effects of L-citrulline in rabbit vascular smooth muscle.
Topics: Animals; Aorta; Cells, Cultured; Citrulline; Cyclic GMP; Dexamethasone; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polysaccharides; Potassium Channels; Purinones; Quinoxalines; Rabbits | 1998 |
Nitrergic neurotransmission mediates the non-adrenergic non-cholinergic responses in the clitoral corpus cavernosum of the rabbit.
Topics: Animals; Arginine; Clitoris; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Purinones; Quinoxalines; Rabbits; Synaptic Transmission; Tetrodotoxin | 1998 |
Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Aorta; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Manganese; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinase C; Purinones; Quinoxalines; Rabbits; Thionucleotides; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
NO releases bombesin-like immunoreactivity from enteric synaptosomes by cross-activation of protein kinase A.
Topics: Animals; Arginine; Bombesin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Intestine, Small; Male; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Purinones; Quinoxalines; Rats; Rats, Wistar; Synaptosomes | 1999 |
Tonic inhibitory action by nitric oxide on spontaneous mechanical activity in rat proximal colon: involvement of cyclic GMP and apamin-sensitive K+ channels.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colon; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Potassium Channels; Purinones; Quinoxalines; Rats; Rats, Wistar | 1999 |
Characterisation of nitrergic transmission in the isolated anococcygeus muscle of the female mouse.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Catechols; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Estrus; Female; Guanylate Cyclase; In Vitro Techniques; Mice; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Synaptic Transmission; Vasoactive Intestinal Peptide; Vasodilator Agents | 1999 |
Cyclic GMP and cyclic AMP induced changes in control and hypertrophic cardiac myocyte function interact through cyclic GMP affected cyclic-AMP phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Milrinone; Oxadiazoles; Oxygen Consumption; Purinones; Quinoxalines | 1999 |
Differential sensitivity among nitric oxide donors toward ODQ-mediated inhibition of vascular relaxation.
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Interactions; Guanylate Cyclase; Male; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2000 |
Spontaneous photo-relaxation of urethral smooth muscle from sheep, pig and rat and its relationship with nitrergic neurotransmission.
Topics: Adenine; Animals; Citrulline; Cold Temperature; Culture Techniques; Electric Stimulation; Enzyme Inhibitors; Female; Light; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Oxadiazoles; Oxyhemoglobins; Phosphodiesterase Inhibitors; Photic Stimulation; Potassium; Purinones; Quinoxalines; Rats; Rats, Wistar; Sheep; Superoxides; Swine; Synaptic Transmission; Tetrodotoxin; Thiourea; Time Factors; Urethra | 2000 |
Decreasing cyclic GMP exerts similar positive functional effects on cardiac myocytes regardless of initial level.
Topics: Animals; Cyclic GMP; Guanylate Cyclase; Heart; In Vitro Techniques; Myocardium; Oxadiazoles; Oxygen Consumption; Purinones; Quinoxalines; Rabbits | 2000 |
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea | 2000 |
Modulation of neuronal nitric oxide release by soluble guanylyl cyclase in guinea pig colon.
Topics: Animals; Arginine; Colon; Cyclic GMP; Dimethyl Sulfoxide; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Immunohistochemistry; Male; Muscle, Smooth; Neurons; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Purinones; Quinoxalines | 2001 |
N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcysteine; Adenosine Diphosphate; Adult; Calcimycin; Cell Membrane Permeability; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Humans; Ionomycin; Male; omega-N-Methylarginine; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinoxalines | 2001 |
The role of cGMP hydrolysing phosphodiesterases 1 and 5 in cerebral artery dilatation.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Basilar Artery; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Isoenzymes; Male; Milrinone; Nitroprusside; Oxadiazoles; Pentoxifylline; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Vasodilation; Vasodilator Agents | 2001 |
Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Purinones; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2001 |
Okadaic acid inhibits relaxant neural transmission in rat gastric fundus in vitro.
Topics: Animals; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Gastrointestinal Agents; Hydrazines; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Okadaic Acid; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Purinones; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide | 2002 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Myosin Light Chains; Nitroglycerin; Norepinephrine; Oxadiazoles; Phosphorylation; Purinones; Quinoxalines; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure.
Topics: Animals; Captopril; Ciliary Body; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intraocular Pressure; Iris; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rabbits; S-Nitrosothiols; Spermine; Swine; Time Factors | 2003 |
5-HT7 receptor-mediated relaxation of the oviduct in nonpregnant proestrus pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrous Cycle; Female; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oviducts; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Purinones; Quinoxalines; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swine; Tritium; Vasoactive Intestinal Peptide | 2003 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline | 2003 |
Role of cyclic GMP in nitrous-oxide-induced anxiolytic-like behavior in the mouse light-dark exploration test.
Topics: Animals; Anxiety; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Male; Mice; Nitrous Oxide; Oxadiazoles; Periodicity; Phosphodiesterase Inhibitors; Purinones; Quinoxalines | 2004 |
Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri.
Topics: Animals; Anthozoa; Body Fluids; California; Guanidines; Immunohistochemistry; Indazoles; Muscle Contraction; Muscles; Neurites; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peristalsis; Phosphodiesterase Inhibitors; Purinones; Quinoxalines | 2005 |
Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analgesics; Animals; Cyclic GMP; Formaldehyde; Glyburide; Injections, Spinal; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Potassium Channels; Purinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Celecoxib; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Perfusion; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Purinones; Pyrazoles; Quinoxalines; Rats; Regional Blood Flow; Signal Transduction; Sildenafil Citrate; Sulfonamides; Sulfones; Vasodilator Agents | 2007 |
Phosphodiesterase type 5 inhibition coupled to strong reinforcement results in two periods of transient retention loss in the young chick.
Topics: Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Chickens; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Memory Disorders; Phosphodiesterase 5 Inhibitors; Purinones; Quinoxalines; Reinforcement, Psychology; Retention, Psychology; Time Factors | 2007 |
Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation.
Topics: Administration, Inhalation; Aerosols; Animals; Benzoates; Cyclic GMP; Dose-Response Relationship, Drug; Drug Combinations; Guanylate Cyclase; Injections, Intravenous; Lung; Morpholines; Nitric Oxide; Oxadiazoles; Particle Size; Phosphodiesterase Inhibitors; Powders; Pulmonary Circulation; Purinones; Pyrazoles; Pyridines; Pyrimidines; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sheep; Soluble Guanylyl Cyclase; Vasodilation | 2007 |
Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways.
Topics: Adenosine Triphosphate; Adult; Aged; Amiloride; Bronchi; Chloride Channels; Colforsin; Cyclic GMP; Cyclic N-Oxides; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Free Radical Scavengers; Guanylate Cyclase; Humans; Imidazoles; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Purinones; Quinoxalines; Young Adult | 2012 |
Preservation of nitric oxide-induced relaxation of porcine coronary artery: roles of the dimers of soluble guanylyl cyclase, phosphodiesterase type 5, and cGMP-dependent protein kinase.
Topics: Animals; Coronary Vessels; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanylate Cyclase; Nitric Oxide; Nitroso Compounds; Oxadiazoles; Phosphodiesterase 5 Inhibitors; Protein Kinase Inhibitors; Protein Multimerization; Purinones; Quinoxalines; Swine; Vasodilation | 2014 |