Page last updated: 2024-08-17

quinoxalines and yohimbine

quinoxalines has been researched along with yohimbine in 184 studies

Research

Studies (184)

TimeframeStudies, this research(%)All Research%
pre-199042 (22.83)18.7374
1990's94 (51.09)18.2507
2000's39 (21.20)29.6817
2010's8 (4.35)24.3611
2020's1 (0.54)2.80

Authors

AuthorsStudies
Paris, H; Remaury, A1
Buchholz, J; Duckles, SP; Friedman, D; Tsai, H1
Coupry, I; Downing, S; Duzic, E; Lanier, SM1
Coupry, I; Duzic, E; Lanier, SM1
Okuma, Y; Reisine, T1
Hansson, E; Nilsson, M; Rönnbäck, L1
Lefebvre, RA; Smits, GJ1
Commissaris, RL; Fontana, DJ1
Crosson, CE; DeVries, GW; Heath, AR; Potter, DE1
Newman, ME1
McClue, SJ; Milligan, G1
Guimarães, JT; Guimarães, S; Moura, D; Nunes, JP; Vaz-da-Silva, MJ1
Minneman, KP; Wilson, KM1
Arthaud, A; Berdeaux, A; Giudicelli, JF; Lambert, C1
Elliott, JM; Glue, P; Kay, G; Nutt, DJ; Payvandi, N1
Dunn, WR; McGrath, JC; Wilson, VG2
Ruff, G; Rump, LC; Schollmeyer, P; Wolk, V1
Bültmann, R; Starke, K; von Kügelgen, I1
Gleason, MM; Hieble, JP1
Healy, D; Horton, RW; Kerry, SM; Lawrence, KM; Paykel, ES; Theodorou, AE; White, W; Whitehouse, AM; Wilton-Cox, H1
Böhm, S; Drobny, H; Huck, S; Singer, EA1
Arnsten, AF; Leslie, FM1
Illes, P; Regenold, JT1
Lafontan, M; Langin, D; Paris, H1
Hayashi, S; Ishima, T; Kano, S; Kimura, K; Matsuzaki, T; Miura, A; Ukai, Y1
Barbe, P; Berlan, M; Estan, L; Guimbaud, R; Louvet, JP; Montastruc, JL; Senard, JM; Tran, MA1
Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D1
Berlan, M; Galitzky, J; Lafontan, M; Montastruc, JL; Senard, JM; Stillings, M1
Alari, L; Axelsson, KL; Persson, ML; Post, C; Uhlén, S; Wikberg, JE1
Akasu, T; Tokimasa, T; Tsurusaki, M1
Guimaraes, S; Nunes, JP1
Rand, MJ; Xiao, XH1
Guimarães, S; Moura, D; Vaz-da-Silva, MJ1
Allen, RM; Kunkel, SL; Remick, DG; Spengler, RN; Strieter, RM1
Brandon, S; Cragoe, EJ; Guyer, CA; Horstman, DA; Limbird, LE; Wilson, AL1
MacLean, MR; McGrath, JC1
Hughes, AD; Martin, GN; Mulvany, MJ; Nielsen, H; Sever, PS; Thom, SM1
Bylund, DB; Ray-Prenger, C1
Galitzky, J; Paris, H; Senard, JM1
Berlan, M; Galitzky, J; Lafontan, M; Mauriege, P1
Berlan, M; Galitzky, J; Lafontan, M; Paris, H1
Fredholm, BB; Hu, PS1
Cattaneo, AG; Doxey, JC; Efendic, S; Ostenson, CG1
Carpéné, C; Lafontan, M; Langin, D; Saulnier-Blache, JS1
Berlan, M; Lafontan, M; Montastruc, P; Taouis, M1
Harker, CT; Vanhoutte, PM1
Gantzos, RD; Neubig, RR; Thomsen, WJ1
Gantzos, RD; Neubig, RR1
Akasu, T; Nishimura, T; Tokimasa, T; Tsurusaki, M1
Daly, CJ; McGrath, JC; Wilson, VG2
Guimarães, S; Paiva, MQ; Polónia, JJ1
Hyman, AL; Kadowitz, PJ2
Bylund, DB; Ray-Prenger, C; Turner, JT1
Brasier, RS; Gantzos, RD; Neubig, RR1
Dickinson, KE; McKernan, RM; Miles, CM; Sever, PS1
Bassenge, E; Elsner, D; Holtz, J; Sommer, O; Stewart, DJ1
Berlan, M; Lafontan, M; Taouis, M1
Itoh, H; Kohli, JD; Rajfer, SI1
Guimarães, S; Moura, D; Paiva, MQ1
Palm, D; Schloos, J; Wellstein, A1
Bylund, DB; Murphy, TJ1
Graham, RM; Powell, WJ; Supple, EW1
Bylund, DB; Petterborg, LJ; Ray-Prenger, C; Rudeen, PK1
Uhlén, S; Wikberg, JE1
Gonçalves, J; Guimarães, S; Nunes, JP; Paiva, MQ1
Messick, K; Ruffolo, RR1
Hyman, AL; Kadowitz, PJ; Lippton, HL1
Pipili, E1
Kassarich, J; Lien, EL; Morrison, A; Sullivan, D1
Flavahan, NA; Gisclard, V; Vanhoutte, PM1
Denis, C; Murat, JC; Paris, H1
Howard, MJ; Insel, PA; McKernan, RM; Motulsky, HJ1
Brandon, S; Cragoe, EJ; Limbird, LE; Nunnari, JM; Repaske, MG1
Bradshaw, CM; Sheridan, RD; Szabadi, E1
Beckeringh, JJ; De Jonge, A; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B1
Limberger, N; Starke, K; Trendelenburg, AU2
Chou, B; Green, PG; Khasar, SG; Levine, JD1
Starke, K; Szabo, B; Urban, R1
Boeckxstaens, GE; De Man, JG; Herman, AG; Pelckmans, PA1
Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG1
Dyamenahalli, U; Haworth, SG; Stuart-Smith, K; Tulloh, RM1
Hara, M; Inoue, M; Irie, T; Mikami, T; Mikami, Y; Minato, A; Omori, K; Uyama, M; Yasukura, T; Zeng, XT1
Szabo, B; Urban, R1
Butler, A; Connor, HE; O'Shaughnessy, CT; Worton, SP1
Duckles, SP; Friedman, DJ1
Regunathan, S; Reis, DJ1
Grassie, MA; Milligan, G1
Qü, M; Schleicher, A; Zilles, K1
Driessen, B; Starke, K; von Kügelgen, I1
Robinson, NE; Wang, Z; Yu, M1
Faber, JE; Ikeoka, K1
Feder, HH; Malik, KF; Morrell, JI1
Kennedy, ME; Limbird, LE1
Vanhoutte, PM; Wood, MB; Ye, Z1
Berlan, M; Galitzky, J; Le Corre, P; Le Verge, R1
Goshima, Y; Misu, Y; Miyamae, T; Okumura, F; Sato, K1
Buchholz, J; Duckles, SP; Tsai, H1
Homey, CJ; Liao, JK1
Blenk, N; Chensue, SW; Giacherio, DA; Kunkel, SL; Spengler, RN1
Bohmann, C; Riera-Knorrenschild, G; Rump, LC; Schollmeyer, P; Schwertfeger, E; Spillner, G1
Brown, DR; Malone, ED; Trent, AM; Turner, TA1
Ogihara, M1
Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM1
Choi, AM; Chung, HS; Fessler, HE; Otterbein, L1
Feltz, P; Hayar, A; Piguet, P1
Szreder, Z1
Itoh, Y; Kimura, K; Oka, M; Shimidzu, T; Ukai, Y; Yoshikuni, Y1
Coupar, IM; Liu, L2
Nörenberg, W; Schöffel, E; Starke, K; Szabo, B1
Elliott, J1
Goldstein, I; Huang, YH; Moreland, RB; Traish, AM1
Guimarães, S; Paiva, MQ; Pereira, O1
Kanagy, NL1
Akaike, N; Arima, J; Ishibashi, H; Kubo, C1
Gallant, CM; Goldstein, I; Gupta, S; Moreland, RB; Traish, A; Yang, S1
Kwan, CY; Mo, FM1
Ohia, SE; Opere, CA1
Aylwin, ML; Bonham, AC; Horowitz, JM1
Audinot, V; Chaput, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Richard, N; Touzard, M; Verrièle, L1
Buerkle, H; Yaksh, TL1
Roomans, GM; Zhang, W1
Hagiwara, T; Kiyose, M; Kobayashi, Y; Kumasaka, S; Muldoon, SM; Okabe, E1
Daniel, EE; Kwan, CY; Loke, JC; Low, AM; Lu-Chao, H1
Schwartz, M; Wheeler, LA; Yoles, E1
Bahia, DS; Jackson, VN; Milligan, G1
Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T1
Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P1
de la Lande, IS; Hennian, E; Marino, V; Parker, DA1
Cox, SL; Gaiser, EG; Meyer, A; Starke, K; Trendelenburg, AU1
Fujiki, H; Imaizumi, T; Kambayashi, J; Kimura, Y; Kishi, M; Mori, T; Orito, K; Shimizu, H; Tanaka, M; Teramoto, S; Tominaga, M; Yoshida, K1
Cockcroft, V; Frang, H; Marjamäki, A; Pihlavisto, M; Scheinin, M1
Eglen, RM; MacLennan, SJ; Martin, GR; Martin, RS; Reynen, PH1
Eglen, RM; MacLennan, SJ; Martin, GR; Reynen, PH1
Benozzi, J; Firpo Lacoste, F; Jaliffa, CO; Keller Sarmiento, MI; Llomovatte, DW; Rosenstein, RE1
Brink, CB; Neubig, RR; Wade, SM1
Lucas-Teixeira, V; Serrão, MP; Soares-da-Silva, P; Vieira-Coelho, MA1
Donello, JE; Gil, DW; Padillo, EU; Webster, ML; Wheeler, LA1
Hein, L; Meyer, A; Nörenberg, W; Starke, K; Trendelenburg, AU1
Cheng, L; Corboz, MR; Egan, RW; Hey, JA; Jakway, J; McCormick, K; Rizzo, CA; Ruck, LM; Shah, H; Umland, SP; Wan, Y1
Han, QD; Sun, W; Tang, YM; Wang, X1
Akerman, S; Goadsby, PJ; Hill, RG; Williamson, DJ1
Chao, HM; Osborne, NN1
Hashimoto, A; Imaizumi, T; Kambe, T; Kishi, M; Mori, T; Nakazawa, T; Orito, K1
Adler-Graschinsky, E; Boric, MP; Figueroa, XF; Huidobro-Toro, JP; Mendizábal, VE; Poblete, MI1
Endo, T; Hamaue, N; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Parvez, H1
Leclere, PG; Lefebvre, RA1
Bishai, JM; Buchholz, JN; Gheorghe, CP; Longo, LD; Meulenaar, R; Nijland, R; Penninga, L; Zhang, L; Zhao, Y1
Burgdorf, C; Engelhardt, A; Kurz, T; Richardt, G; Schäfer, U1
Artigues-Varin, C; Mulder, P; Richard, V; Thuillez, C; Varin, R1
Kalkman, HO; Loetscher, E1
Deruelle, P; Houfflin-Debarge, V; Jaillard, S; Klosowski, S; Magnenant, E; Riou, Y; Storme, L1
Ogidigben, MJ; Potter, DE1
Barbara, G; Baschiera, F; Blandizzi, C; Breschi, MC; Colucci, R; De Giorgio, R; De Ponti, F; Del Tacca, M; Fornai, M1
Duman, RS; Russell, DS; Tolbert, LM1
Burgdorf, C; Engelhardt, A; Kurz, T; Raasch, W; Richardt, G; Schäfer, U1
Foehring, RC; Geisert, E; Lorenzon, NM; Stewart, AE; Timmons, SD1
Dang, VC; Williams, JT1
Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T1
Ignatowski, TA; Reynolds, JL; Spengler, RN1
Ignatowski, TA; Reynolds, JL; Spengler, RN; Sud, R1
Burgdorf, C; Dendorfer, A; Kurz, T; Richardt, G; Schütte, F1
Gutkowska, J; Menaouar, A; Mukaddam-Daher, S1
Castillo, C; Castillo, EF; López, RM; Ortíz, CS; Ruíz, A; Vélez, JM1
Buranakarl, C; Chaiyabutr, N; Suwanwipat, S1
Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H1
Bayer, L; Eggermann, E; Jones, BE; Mühlethaler, M; Saint-Mleux, B; Serafin, M1
Alpini, G; Alvaro, D; Benedetti, A; DeMorrow, S; Francis, H; Glaser, S; LeSage, G; Mancino, MG; Marucci, L; Ueno, Y; Venter, J1
Bustamante, S; García-Sacristán, A; Hernández, M; Martínez, MP; Navarro-Dorado, J; Orensanz, LM; Prieto, D; Recio, P1
Perkel, DJ; Sizemore, M1
Arttamangkul, S; Birdsong, WT; Virk, MS; Williams, JT1
Ali, U; Chen, L; Gui, ZH; Hui, YP; Li, Q; Liu, J; Wang, T; Wang, Y; Zhang, QJ1
Centurión, D; Hofmann, RA; Jantschak, F; Pertz, HH; Popp, AM; Villalón, CM1
Debacker, J; Dumont, EC; Jones, AA; Krawczyk, M; Mason, X; Sharma, R1
Adorjan, I; Bauer, L; Belz, M; Brunmair, B; de Cillia, VA; Fenzl, A; Frobel, K; Fürnsinn, C; Gruber, D; Lehner, Z; Luger, A; Rustenbeck, I; Stadlbauer, K1
Cai, J; Han, Y; Li, J; Liu, W; Wang, H1
Bult, H; De Meyer, GR; Fransen, P; Martinet, W; Schrijvers, DM; Van Hove, CE; van Langen, JT1
Abassi, YA; Irelan, J; Ke, N; Nguyen, K1
Lewczuk, B; Przybylska-Gornowicz, B; Ziółkowska, N1
Alsufyani, HA; Docherty, JR; McCormick, PA1

Other Studies

184 other study(ies) available for quinoxalines and yohimbine

ArticleYear
The insulin-secreting cell line, RINm5F, expresses an alpha-2D adrenoceptor and nonadrenergic idazoxan-binding sites.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Cell Line; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Idazoxan; Immunoblotting; Insulin; Insulin Secretion; Kinetics; Membranes; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tritium; Virulence Factors, Bordetella; Yohimbine

1992
Influence of age on control of norepinephrine release from the rat tail artery.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Norepinephrine; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Dopamine; Tail; Yohimbine

1992
Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. I. Coupling of alpha 2-adrenergic receptor subtypes to distinct G-proteins.
    The Journal of biological chemistry, 1992, May-15, Volume: 267, Issue:14

    Topics: 3T3 Cells; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Membrane; Colforsin; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Mice; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Signal Transduction; Transfection; Virulence Factors, Bordetella; Yohimbine

1992
Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. II. Preferential coupling of the alpha 2C-adrenergic receptor to the guanine nucleotide-binding protein, Go.
    The Journal of biological chemistry, 1992, May-15, Volume: 267, Issue:14

    Topics: 3T3 Cells; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Membrane; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Immunoblotting; Kinetics; Membrane Proteins; Mice; Plasmids; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha; Signal Transduction; Transfection; Yohimbine

1992
Immunoprecipitation of alpha 2a-adrenergic receptor-GTP-binding protein complexes using GTP-binding protein selective antisera. Changes in receptor/GTP-binding protein interaction following agonist binding.
    The Journal of biological chemistry, 1992, Jul-25, Volume: 267, Issue:21

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Line; Clonidine; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immune Sera; Iodine Radioisotopes; Precipitin Tests; Quinoxalines; Receptors, Adrenergic, alpha; Swine; Yohimbine

1992
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
    Neuroscience letters, 1992, Feb-17, Volume: 136, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine

1992
Modulation of non-adrenergic non-cholinergic inhibitory neurotransmission in rat gastric fundus by the alpha 2-adrenoceptor agonist, UK-14,304.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Autonomic Nervous System; Brimonidine Tartrate; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Prazosin; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide; Yohimbine

1992
Anxiolytic-like effects of alpha-2-adrenoceptor agonists on conflict behavior in the rat: pre- versus postsynaptic receptor mechanisms.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Benzylamines; Brain Chemistry; Brimonidine Tartrate; Conflict, Psychological; Female; Mydriatics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathomimetics; Synapses; Yohimbine

1992
Pharmacological evidence for heterogeneity of ocular alpha 2 adrenoceptors.
    Current eye research, 1992, Volume: 11, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cats; Ciliary Body; Cyclic AMP; Dose-Response Relationship, Drug; Iris; Nictitating Membrane; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine

1992
Serotonin inhibits adenylate cyclase in human platelet membranes.
    European journal of pharmacology, 1992, Aug-03, Volume: 226, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Binding Sites; Blood Platelets; Colforsin; Dose-Response Relationship, Drug; Humans; Methysergide; Quinoxalines; Receptors, Serotonin; Serotonin; Spiperone; Yohimbine

1992
Molecular interaction of the human alpha 2-C10-adrenergic receptor, when expressed in Rat-1 fibroblasts, with multiple pertussis toxin-sensitive guanine nucleotide-binding proteins: studies with site-directed antisera.
    Molecular pharmacology, 1991, Volume: 40, Issue:5

    Topics: Animals; Brimonidine Tartrate; Cells, Cultured; Fibroblasts; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Immune Sera; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine

1991
Alpha 1- and alpha 2-adrenoceptors at different levels of the canine saphenous vein.
    Journal of neural transmission. Supplementum, 1991, Volume: 34

    Topics: Animals; Brimonidine Tartrate; Dioxanes; Dogs; Electric Stimulation; Epinephrine; In Vitro Techniques; Inositol; Inositol Phosphates; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Synapses; Yohimbine

1991
Synergistic interactions between alpha 1- and alpha 2-adrenergic receptors in activating 3H-inositol phosphate formation in primary glial cell cultures.
    Journal of neurochemistry, 1991, Volume: 56, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Cells, Cultured; Dose-Response Relationship, Drug; Inositol Phosphates; Neuroglia; Norepinephrine; Osmolar Concentration; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Time Factors; Tritium; Yohimbine

1991
Alpha-adrenoceptor subtypes and regional myocardial blood flow distribution during coronary occlusion in dogs.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Coronary Circulation; Coronary Vessels; Dogs; Female; Imidazoles; Male; Muscle, Smooth, Vascular; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1991
Effects of chronic alpha 2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers.
    Life sciences, 1991, Volume: 49, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Humans; Idazoxan; Lymphocytes; Male; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Up-Regulation; Yohimbine

1991
Postjunctional alpha-adrenoceptors in the rabbit isolated distal saphenous artery: indirect sensitivity to prazosin of responses to noradrenaline mediated via postjunctional alpha 2-adrenoceptors.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Yohimbine

1991
Alpha 2-adrenoceptor activation inhibits noradrenaline release in human and rabbit isolated renal arteries.
    European journal of pharmacology, 1991, Apr-24, Volume: 196, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Animals; Brimonidine Tartrate; Clonidine; Female; Humans; In Vitro Techniques; Kidney; Male; Middle Aged; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renal Artery; Sympathetic Nervous System; Tetrodotoxin; Yohimbine

1991
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:6

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine

1991
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine

1991
Platelet alpha 2-adrenoceptors, defined with agonist and antagonist ligands, in depressed patients, prior to and following treatment.
    Journal of affective disorders, 1991, Volume: 23, Issue:3

    Topics: Adrenergic alpha-Agonists; Binding, Competitive; Blood Platelets; Brimonidine Tartrate; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Lofepramine; Psychiatric Status Rating Scales; Quinoxalines; Radioligand Assay; Receptors, Adrenergic; Yohimbine

1991
Electrically evoked noradrenaline release from cultured chick sympathetic neurons: modulation via presynaptic alpha-adrenoceptors and lack of autoinhibition.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Chick Embryo; Cocaine; Electric Stimulation; Neurons; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Sympathetic Nervous System; Tritium; Yohimbine

1991
Behavioral and receptor binding analysis of the alpha 2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-yl amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an alpha 2-adrenoceptor subtype.
    Neuropharmacology, 1991, Volume: 30, Issue:12A

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Behavior, Animal; Blood Pressure; Brain; Brimonidine Tartrate; Cognition; Dioxanes; Female; Guanfacine; Hypnotics and Sedatives; Idazoxan; Macaca mulatta; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Yohimbine

1991
Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons.
    Nature, 1990, Mar-01, Volume: 344, Issue:6261

    Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Locus Coeruleus; Neuropeptide Y; Norepinephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu; Thionucleotides; Yohimbine

1990
Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites.
    Molecular pharmacology, 1990, Volume: 37, Issue:6

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Binding Sites; Brimonidine Tartrate; Cell Membrane; Cystamine; Dioxanes; Dioxins; Epinephrine; Female; Humans; Idazoxan; Magnesium Chloride; Phenoxybenzamine; Potassium Chloride; Quinoxalines; Tritium; Yohimbine

1990
[Pharmacological studies of celiprolol: II. Alpha 2-Adrenoceptor blocking effects of a cardioselective beta-blocker, celiprolol].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 95, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteries; Blood Pressure; Brimonidine Tartrate; Celiprolol; In Vitro Techniques; Male; Muscle Contraction; Propanolamines; Quinoxalines; Rats; Rats, Inbred Strains; Tail; Tetrodotoxin; Vas Deferens; Vasoconstriction; Yohimbine

1990
Decreased high affinity state in platelet alpha 2-adrenoceptors from diabetic patients with orthostatic hypotension.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Blood Platelets; Brimonidine Tartrate; Cell Membrane; Diabetes Mellitus; Diabetic Neuropathies; Female; Glycated Hemoglobin; Humans; Hypotension, Orthostatic; Kinetics; Male; Middle Aged; Pressoreceptors; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1990
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1990
Identification of human platelet alpha 2-adrenoceptors with a new antagonist [3H]-RX821002, a 2-methoxy derivative of idazoxan.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; In Vitro Techniques; Kinetics; Male; Membranes; Oxymetazoline; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine

1990
Antinociceptive actions of alpha 2-adrenoceptor agonists in the rat spinal cord: evidence for antinociceptive alpha 2-adrenoceptor subtypes and dissociation of antinociceptive alpha 2-adrenoceptors from cyclic AMP.
    Journal of neurochemistry, 1990, Volume: 55, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Benzylamines; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guanfacine; Male; Neurotoxins; Nociceptors; Pain Measurement; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine

1990
Reduction of the N-type calcium current by noradrenaline in neurones of rabbit vesical parasympathetic ganglia.
    The Journal of physiology, 1990, Volume: 426

    Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Barium; Brimonidine Tartrate; Calcium Channels; Ganglia, Parasympathetic; In Vitro Techniques; Male; Membrane Potentials; Neurons; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Time Factors; Yohimbine

1990
The effectiveness of alpha 2-adrenoceptor activation increases from the distal to the proximal part of the veins of canine limbs.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Dogs; Extremities; Female; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Saphenous Vein; Veins; Yohimbine

1990
Effects of the alpha 2-adrenoceptor agonist UK14304 on pressor responses in pithed rats.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Drug Synergism; Norepinephrine; Phenylephrine; Prazosin; Pressoreceptors; Quinoxalines; Rats; Vasopressins; Yohimbine

1990
Alpha-adrenoceptor reserve in the canine cephalic vein.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Forelimb; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Veins; Yohimbine

1990
Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Sep-01, Volume: 145, Issue:5

    Topics: Animals; Base Sequence; Brimonidine Tartrate; Cell Line; Dose-Response Relationship, Drug; Female; Gene Expression; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred CBA; Molecular Sequence Data; Norepinephrine; Oligonucleotide Probes; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Tumor Necrosis Factor-alpha; Yohimbine

1990
An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Affinity Labels; Allosteric Regulation; Amino Acid Sequence; Animals; Aspartic Acid; Brimonidine Tartrate; Dioxanes; DNA Mutational Analysis; Epinephrine; Idazoxan; In Vitro Techniques; Molecular Sequence Data; Oxymetazoline; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Structure-Activity Relationship; Swine; Transfection; Yohimbine

1990
Effects of pre-contraction with endothelin-1 on alpha 2-adrenoceptor- and (endothelium-dependent) neuropeptide Y-mediated contractions in the isolated vascular bed of the rat tail.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Blood Pressure; Brimonidine Tartrate; Cholic Acids; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Tail; Yohimbine

1990
Postjunctional alpha 2-adrenoceptors mediate vasoconstriction in human subcutaneous resistance vessels.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arteries; Azepines; Brimonidine Tartrate; Doxazosin; Female; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Skin; Vascular Resistance; Vasoconstriction; Veins; Yohimbine

1989
Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: Animals; Brimonidine Tartrate; Cyclic AMP; Humans; Isoquinolines; Piperazines; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine

1989
Expression of functional postjunctional alpha 2-adrenoceptors in rabbit isolated distal saphenous artery--a permissive role for angiotensin II?
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arteries; Brimonidine Tartrate; Drug Interactions; In Vitro Techniques; Male; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine

1989
Interactions of full and partial agonists with HT29 cell alpha 2-adrenoceptor: comparative study of [3H]UK-14,304 and [3H]clonidine binding.
    Molecular pharmacology, 1989, Volume: 35, Issue:3

    Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guanylyl Imidodiphosphate; Kinetics; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Tritium; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Yohimbine

1989
Human fat cell alpha-2 adrenoceptors. I. Functional exploration and pharmacological definition with selected alpha-2 agonists and antagonists.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Brimonidine Tartrate; Cystamine; Female; Guanosine Triphosphate; Humans; Lipolysis; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1989
Human fat cell alpha-2 adrenoceptors. II. Comparative study of partial and full agonist binding parameters using [3H]clonidine and [3H]UK-14,304.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Allosteric Regulation; Binding, Competitive; Brimonidine Tartrate; Clonidine; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Magnesium; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1989
Alpha 2-adrenoceptor agonist-mediated inhibition of [3H]noradrenaline release from rat hippocampus is reduced by 4-aminopyridine, but that caused by an adenosine analogue or omega-conotoxin is not.
    Acta physiologica Scandinavica, 1989, Volume: 136, Issue:3

    Topics: 4-Aminopyridine; Adenosine; Adrenergic alpha-Agonists; Aminopyridines; Animals; Brimonidine Tartrate; Cadmium; Cadmium Chloride; Conotoxins; Hippocampus; Male; Mollusk Venoms; Norepinephrine; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Inbred Strains; Yohimbine

1989
Alpha-adrenoceptors and insulin release from pancreatic islets of normal and diabetic rats.
    The American journal of physiology, 1989, Volume: 257, Issue:3 Pt 1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Diabetes Mellitus, Experimental; Dioxanes; Female; Glucose; Idazoxan; Insulin; Islets of Langerhans; Male; Phentolamine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Streptozocin; Yohimbine

1989
Imidazolinic radioligands for the identification of hamster adipocyte alpha 2-adrenoceptors.
    European journal of pharmacology, 1989, Nov-21, Volume: 171, Issue:2-3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cricetinae; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipolysis; Male; Mesocricetus; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine

1989
Characterization of dog fat cell adrenoceptors: variations in alpha-2 and beta adrenergic receptors distribution according to the extent of the fat deposits and the anatomical location.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adipose Tissue; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dihydroalprenolol; Dogs; Epinephrine; Humans; Isoproterenol; Lipolysis; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine

1987
Cooling the central ear artery of the rabbit: myogenic and adrenergic responses.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Adenosine Triphosphate; Animals; Arteries; Brimonidine Tartrate; Calcium; Cold Temperature; Ear; Electric Stimulation; Indomethacin; Male; Norepinephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Tetrodotoxin; Vasoconstriction; Yohimbine

1988
Mechanism of agonist and antagonist binding to alpha 2 adrenergic receptors: evidence for a precoupled receptor-guanine nucleotide protein complex.
    Biochemistry, 1988, Apr-05, Volume: 27, Issue:7

    Topics: Antihypertensive Agents; Blood Platelets; Brimonidine Tartrate; Cell Membrane; GTP-Binding Proteins; Humans; Kinetics; Mathematics; Models, Biological; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1988
Temperature effects on alpha 2-adrenergic receptor-Gi interactions.
    Biochemical pharmacology, 1988, Jul-15, Volume: 37, Issue:14

    Topics: Adenylyl Cyclase Inhibitors; Brimonidine Tartrate; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Quinoxalines; Receptors, Adrenergic, alpha; Temperature; Yohimbine

1988
Norepinephrine inhibits calcium action potential through alpha 2-adrenoceptors in rabbit vesical parasympathetic neurons.
    Neuroscience research, 1988, Volume: 6, Issue:2

    Topics: Action Potentials; Animals; Brimonidine Tartrate; Calcium; Clonidine; Ganglia, Parasympathetic; Male; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine

1988
An examination of the postjunctional alpha-adrenoceptor subtypes for (-)-noradrenaline in several isolated blood vessels from the rabbit.
    British journal of pharmacology, 1988, Volume: 95, Issue:2

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Brimonidine Tartrate; Ear; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renal Veins; Saphenous Vein; Stereoisomerism; Yohimbine

1988
Pharmacological characterization of postsynaptic alpha-adrenoceptor subtypes in five different dog arteries in-vitro.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:3

    Topics: Animals; Antihypertensive Agents; Arteries; Brimonidine Tartrate; Cocaine; Dogs; In Vitro Techniques; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Propiophenones; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine

1985
Evidence for existence of postjunctional alpha 1- and alpha 2-adrenoceptors in cat pulmonary vascular bed.
    The American journal of physiology, 1985, Volume: 249, Issue:4 Pt 2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cats; Female; Male; Methoxamine; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Pulmonary Veins; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine

1985
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
    Molecular pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine

1985
Agonist and antagonist binding to alpha 2-adrenergic receptors in purified membranes from human platelets. Implications of receptor-inhibitory nucleotide-binding protein stoichiometry.
    Molecular pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Clonidine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; NAD; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1985
Enhancement of alpha- and beta-adrenoceptor responses by elevations in vascular tone in pulmonary circulation.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cats; Female; Male; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propanolamines; Pulmonary Circulation; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine

1986
Heterogeneity between soluble human and rabbit splenic alpha 2-adrenoceptors.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; Lectins; Oxymetazoline; Phentolamine; Prazosin; Quinolizines; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Solubility; Spleen; Sulfhydryl Reagents; Yohimbine

1986
Postsynaptic alpha 1- and alpha 2-adrenergic receptors in adrenergic control of capacitance vessel tone in vivo.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Brimonidine Tartrate; Compliance; Dogs; Female; Male; Methoxamine; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Splanchnic Circulation; Splenectomy; Tyramine; Vasoconstriction; Yohimbine

1986
Alpha 2-adrenergic receptor turnover in adipose tissue and kidney: irreversible blockade of alpha 2-adrenergic receptors by benextramine.
    Molecular pharmacology, 1987, Volume: 31, Issue:1

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Clonidine; Cricetinae; Cystamine; Dose-Response Relationship, Drug; Kidney; Lipid Mobilization; Male; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1987
Pharmacological characterization of the postsynaptic alpha-adrenoceptors in isolated canine mesenteric arteries and veins.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dogs; Dopamine; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Synapses; Yohimbine

1987
Alpha 2-adrenoceptor-mediated responses to so-called selective alpha 1-adrenoceptor agonists after partial blockade of alpha 1-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dogs; Drug Interactions; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Verapamil; Yohimbine

1987
Agonist binding at alpha 2-adrenoceptors of human platelets using 3H-UK-14,304: regulation by Gpp(NH)p and cations.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antihypertensive Agents; Binding, Competitive; Blood Platelets; Brimonidine Tartrate; Cations; Cell Membrane; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Ligands; Magnesium; Magnesium Chloride; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1987
Characterization of alpha-2 adrenergic receptors in the OK cell, an opossum kidney cell line.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Line; Cyclic AMP; Kidney; Kinetics; Opossums; Parathyroid Hormone; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine

1988
Direct effects of alpha 2-adrenergic receptor stimulation on intravascular systemic capacity in the dog.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Volume; Brimonidine Tartrate; Cardiopulmonary Bypass; Central Venous Pressure; Dogs; Hepatic Veins; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Tachyphylaxis; Vascular Resistance; Yohimbine

1988
Identification of alpha 2-adrenergic receptors in chicken pineal gland using [3H]rauwolscine.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane; Chickens; Circadian Rhythm; Female; Isoquinolines; Male; Pindolol; Pineal Gland; Piperazines; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Yohimbine

1988
Inhibition of cyclic AMP production by alpha 2-adrenoceptor stimulation in the guinea-pig spinal cord slices.
    Pharmacology & toxicology, 1988, Volume: 63, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Quinoxalines; Spinal Cord; Yohimbine

1988
Loss of selectivity of so-called selective alpha 1-adrenoceptor agonists after phenoxybenzamine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1988
Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly alpha 2.
    British journal of pharmacology, 1988, Volume: 94, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Veins; Yohimbine

1988
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Tolazoline; Yohimbine

1985
Nature of alpha 1 and postjunctional alpha 2 adrenoceptors in the pulmonary vascular bed.
    Federation proceedings, 1986, Volume: 45, Issue:9

    Topics: Animals; Azepines; Blood Pressure; Brimonidine Tartrate; Cats; Hydroxydopamines; Methoxamine; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine

1986
A study on the postjunctional excitatory alpha-adrenoreceptor subtypes in the mesenteric arterial bed of the rat.
    Journal of autonomic pharmacology, 1986, Volume: 6, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Yohimbine

1986
Alpha-2-adrenergic control of prolactin release.
    Neuroendocrinology, 1986, Volume: 44, Issue:2

    Topics: Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Male; Piperoxan; Pregnancy; Prolactin; Quinolizines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1986
Alpha adrenergic responses of blood vessels of rabbits after ovariectomy and administration of 17 beta-estradiol.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Animals; Blood Vessels; Brimonidine Tartrate; Estradiol; Female; Muscle, Smooth, Vascular; Norepinephrine; Ovariectomy; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Vasomotor System; Yohimbine

1987
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line. Alpha 2-adrenergic agonists counteract effect of vasoactive intestinal peptide.
    The Biochemical journal, 1986, Nov-01, Volume: 239, Issue:3

    Topics: Adenocarcinoma; Brimonidine Tartrate; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Epinephrine; Fructosediphosphates; Hexosediphosphates; Humans; Quinoxalines; Vasoactive Intestinal Peptide; Yohimbine

1986
Compartmentation of alpha 2-adrenergic receptors in human erythroleukemia (HEL) cells.
    Molecular pharmacology, 1987, Volume: 32, Issue:1

    Topics: Adenylyl Cyclases; Brimonidine Tartrate; Cell Compartmentation; Cell Membrane; Cyclic AMP; Epinephrine; GTP-Binding Proteins; Humans; Leukemia, Erythroblastic, Acute; Quinoxalines; Receptors, Adrenergic, alpha; Temperature; Yohimbine

1987
Regulation of porcine brain alpha 2-adrenergic receptors by Na+,H+ and inhibitors of Na+/H+ exchange.
    The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25

    Topics: Amiloride; Animals; Brain Chemistry; Brimonidine Tartrate; Carrier Proteins; Cerebral Cortex; Epinephrine; Hydrogen; Hydrogen-Ion Concentration; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Sodium-Hydrogen Exchangers; Swine; Yohimbine

1987
Neuronal responses to noradrenaline in the cerebral cortex: evidence against the involvement of alpha 2-adrenoceptors.
    British journal of pharmacology, 1984, Volume: 82, Issue:2

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Dioxanes; Idazoxan; Male; Neurons; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1984
The contractions induced in rat and guinea-pig aortic strips by the alpha 2-adrenoceptor selective agonists B-HT 920 and UK 14,304 are mediated by alpha 1-adrenoceptors.
    European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine

1984
Subclassification of presynaptic alpha 2-adrenoceptors: alpha 2D-autoreceptors in mouse brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Autoreceptors; Binding, Competitive; Brain; Brimonidine Tartrate; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Presynaptic Terminals; Quinoxalines; Receptors, Adrenergic, alpha-2; Tetrodotoxin; Yohimbine

1995
Subclassification of presynaptic alpha 2-adrenoceptors: alpha 2D-autoreceptors in guinea-pig atria and brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Autoreceptors; Brimonidine Tartrate; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Phentolamine; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine

1995
Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat.
    Neuroscience, 1995, Volume: 66, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Calcimycin; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Indoles; Isoindoles; Male; Norepinephrine; Pain Measurement; Peripheral Nervous System; Quinoxalines; Rats; Rats, Sprague-Dawley; Yohimbine

1995
Involvement of alpha 2-adrenoceptors in the cardiovascular effects of moxonidine.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cisterna Magna; Female; Heart Rate; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Male; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine

1995
Effect of potassium channel blockade and alpha 2-adrenoceptor activation on the release of nitric oxide from non-adrenergic non-cholinergic nerves.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Arginine; Autonomic Nervous System; Brimonidine Tartrate; Charybdotoxin; Dogs; Electric Stimulation; Female; Male; Nitric Oxide; Nitroarginine; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Tetraethylammonium Compounds; Tetrodotoxin; Yohimbine

1994
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine

1995
Adrenoceptor-stimulated endothelium-dependent relaxation in porcine intrapulmonary arteries.
    Pulmonary pharmacology, 1994, Volume: 7, Issue:5

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Pulmonary Artery; Quinoxalines; Swine; Yohimbine

1994
Adrenergic receptor-mediated Cl- transport in rabbit corneal endothelial cells.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:4

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetazolamide; Adrenergic Agonists; Adrenergic Antagonists; Affinity Labels; Animals; Brimonidine Tartrate; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorescent Dyes; Ion Transport; Isoproterenol; Microscopy, Fluorescence; Norepinephrine; Phentolamine; Phenylephrine; Photometry; Quinolines; Quinoxalines; Rabbits; Receptors, Adrenergic; Yohimbine

1995
Mechanism of sympathoinhibition by imidazolines.
    Annals of the New York Academy of Sciences, 1995, Jul-12, Volume: 763

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Brimonidine Tartrate; Dioxanes; Hemodynamics; Idazoxan; Imidazoles; Oxazoles; Quinoxalines; Rabbits; Rilmenidine; Sympathetic Nervous System; Yohimbine

1995
Sensory nerve-mediated relaxation of guinea-pig isolated pulmonary artery: prejunctional modulation by alpha 2-adrenoceptor agonists but not sumatriptan.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcitonin Gene-Related Peptide; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Junction; Neurons, Afferent; Piperazines; Pulmonary Artery; Pyrrolidines; Quinoxalines; Substance P; Sulfonamides; Sumatriptan; Vasoconstrictor Agents; Yohimbine

1993
Prejunctional interaction of alpha 2-adrenoceptors and D2 dopamine receptors on perivascular sympathetic nerves.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Dopamine D2; Sympathetic Nervous System; Tail; Tetrahydronaphthalenes; Thiophenes; Yohimbine

1995
Effects of moxonidine, an imidazoline antihypertensive agent, on second messenger systems in rat brain.
    European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Chemistry; Brain Stem; Brimonidine Tartrate; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Norepinephrine; Phosphatidylinositols; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Yohimbine

1994
Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts.
    The Biochemical journal, 1995, Mar-01, Volume: 306 ( Pt 2)

    Topics: Adenosine Diphosphate Ribose; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cholera Toxin; Fibroblasts; Gene Expression; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Immunosorbent Techniques; NAD; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Transfection; Virulence Factors, Bordetella; Yohimbine

1995
Regional distribution and heterogeneity of alpha-adrenoceptors in the rat and human central nervous system.
    Journal fur Hirnforschung, 1993, Volume: 34, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Brain; Brain Chemistry; Brimonidine Tartrate; Humans; Organ Specificity; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Species Specificity; Tritium; Yohimbine

1993
Neural ATP release and its alpha 2-adrenoceptor-mediated modulation in guinea-pig vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Suramin; Vas Deferens; Yohimbine

1993
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine

1993
ANG II reverses selective inhibition of alpha 2-adrenoceptor sensitivity after in vitro isolation of arterioles.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arterioles; Brimonidine Tartrate; Histological Techniques; In Vitro Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine

1993
Effects of alpha-2-adrenergic drugs in the medial preoptic area and medial basal hypothalamus on lordosis in the guinea pig.
    Brain research, 1993, Nov-19, Volume: 628, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Estradiol; Female; Guinea Pigs; Hypothalamus, Middle; Posture; Preoptic Area; Progesterone; Quinoxalines; Receptors, Adrenergic, alpha-2; Sexual Behavior, Animal; Synaptic Transmission; Yohimbine

1993
Palmitoylation of the alpha 2A-adrenergic receptor. Analysis of the sequence requirements for and the dynamic properties of alpha 2A-adrenergic receptor palmitoylation.
    The Journal of biological chemistry, 1994, Dec-16, Volume: 269, Issue:50

    Topics: Acylation; Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Base Sequence; Brimonidine Tartrate; DNA Primers; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Palmitates; Protein Processing, Post-Translational; Quinoxalines; Receptors, Adrenergic, alpha; Recombinant Proteins; Structure-Activity Relationship; Swine; Yohimbine

1994
Alpha-adrenergic receptor responsiveness in vascular smooth muscle of canine bone.
    Clinical orthopaedics and related research, 1993, Issue:287

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Tibia; Yohimbine

1993
Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Blood Proteins; Brimonidine Tartrate; Cell Membrane; Dioxanes; Epinephrine; Humans; Hydroxylation; Idazoxan; In Vitro Techniques; Lipolysis; Male; Platelet Aggregation; Protein Binding; Quinoxalines; Yohimbine

1993
L-dopa potentiates presynaptic inhibitory alpha 2-adrenoceptor- but not facilitatory angiotensin II receptor-mediated modulation of noradrenaline release from rat hypothalamic slices.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Brimonidine Tartrate; Hypothalamus; In Vitro Techniques; Levodopa; Male; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Synapses; Yohimbine

1993
Postjunctional alpha 2-adrenoceptors in blood vessels: effect of age.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Methoxamine; Norepinephrine; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Tail; Vasoconstriction; Yohimbine

1993
The release of endothelium-derived relaxing factor via alpha 2-adrenergic receptor activation is specifically mediated by Gi alpha 2.
    The Journal of biological chemistry, 1993, Sep-15, Volume: 268, Issue:26

    Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Aorta; Binding, Competitive; Brimonidine Tartrate; Cattle; Cells, Cultured; Endothelium, Vascular; Epinephrine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Immune Sera; Kinetics; Molecular Sequence Data; Muscle, Smooth, Vascular; NAD; Nitric Oxide; Oligopeptides; Pertussis Toxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine

1993
Endogenous norepinephrine regulates tumor necrosis factor-alpha production from macrophages in vitro.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Mar-15, Volume: 152, Issue:6

    Topics: Animals; Base Sequence; Brimonidine Tartrate; Cells, Cultured; Dose-Response Relationship, Drug; Female; Isoproterenol; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred CBA; Molecular Sequence Data; Norepinephrine; Quinoxalines; Tumor Necrosis Factor-alpha; Yohimbine

1994
Dopaminergic and alpha-adrenergic control of neurotransmission in human right atrium.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Benzazepines; Brimonidine Tartrate; Domperidone; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Ergolines; Female; Fenoldopam; Heart Atria; Humans; In Vitro Techniques; Male; Methoxamine; Middle Aged; Norepinephrine; Prazosin; Quinoxalines; Quinpirole; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Synaptic Transmission; Yohimbine

1995
Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Acetylcholine; Adrenergic Agonists; Adrenergic Antagonists; Animals; Atropine; Brimonidine Tartrate; Calcium Channel Blockers; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Horses; Isoproterenol; Jejunum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Quinoxalines; Sympathetic Nervous System; Tetrodotoxin; Verapamil; Yohimbine

1996
Cell-density-dependent expression of the alpha(2)-adrenergic response by epidermal growth factor (EGF) in primary cultures of adult rat hepatocytes.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin B; Epidermal Growth Factor; Genistein; Isoflavones; Liver; Male; Oxymetazoline; Pertussis Toxin; Protein Biosynthesis; Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine

1996
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine

1996
Alpha-2 adrenoceptor blockade protects rats against lipopolysaccharide.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:6 Pt 1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Creatinine; Escherichia coli; Hemodynamics; Lipopolysaccharides; Lung; Male; Peroxidase; Quinoxalines; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Necrosis Factor-alpha; Xylazine; Yohimbine

1996
Adrenergic responses in silent and putative inhibitory pacemaker-like neurons of the rat rostral ventrolateral medulla in vitro.
    Neuroscience, 1997, Volume: 77, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Bicuculline; Biological Clocks; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; Interneurons; Ion Channel Gating; Isoproterenol; Medulla Oblongata; Norepinephrine; Prazosin; Quinoxalines; Rats; Rats, Wistar; Strychnine; Synaptic Transmission; Tetrodotoxin; Yohimbine

1997
Do cardiovascular mechanisms participate in thermoregulatory activity of alpha 2-adrenoceptor agonists and antagonists in rabbits?
    Annals of the New York Academy of Sciences, 1997, Mar-15, Volume: 813

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Body Temperature; Body Temperature Regulation; Brimonidine Tartrate; Cold Temperature; Ear; Energy Metabolism; Fever; Hemodynamics; Lipopolysaccharides; Male; Pyrogens; Quinoxalines; Rabbits; Yohimbine

1997
Involvement of metabotropic glutamate receptors in Gi- and Gs-dependent modulation of adenylate cyclase activity induced by a novel cognition enhancer NS-105 in rat brain.
    Brain research, 1997, Apr-18, Volume: 754, Issue:1-2

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alanine; Animals; Baclofen; Brimonidine Tartrate; Cell Membrane; Cerebral Cortex; Cholera Toxin; Cognition; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoproterenol; Kinetics; Male; Manganese; Pertussis Toxin; Piperidines; Proline; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella; Yohimbine

1997
Role of alpha 2-adrenoceptors in the regulation of intestinal water transport.
    British journal of pharmacology, 1997, Volume: 120, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Transport; Brimonidine Tartrate; Dose-Response Relationship, Drug; Female; Ileum; Imidazoles; Indoles; Intestinal Absorption; Isoindoles; Isoquinolines; Jejunum; Male; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasoactive Intestinal Peptide; Water; Yohimbine

1997
Subtype determination of soma-dendritic alpha2-autoreceptors in slices of rat locus coeruleus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:2

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Dendrites; In Vitro Techniques; Locus Coeruleus; Maprotiline; Neurons; Norepinephrine; Phentolamine; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Yohimbine

1997
Alpha-adrenoceptors in equine digital veins: evidence for the presence of both alpha1 and alpha2-receptors mediating vasoconstriction.
    Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dopamine; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Veins; Yohimbine

1997
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
    Receptors & signal transduction, 1997, Volume: 7, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine

1997
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine

1997
Involvement of alpha-2 adrenoceptors in the effects of moxonidine on intestinal motility and fluid transport.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Agmatine; Animals; Body Water; Brimonidine Tartrate; Dose-Response Relationship, Drug; Gastrointestinal Motility; Imidazoles; Male; Peristalsis; Quinolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasoactive Intestinal Peptide; Yohimbine

1997
Increased vascular responsiveness to alpha 2-adrenergic stimulation during NOS inhibition-induced hypertension.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Brimonidine Tartrate; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Systole; Vasoconstriction; Yohimbine

1997
alpha2-Adrenoceptor-mediated potassium currents in acutely dissociated rat locus coeruleus neurones.
    The Journal of physiology, 1998, Apr-01, Volume: 508 ( Pt 1)

    Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane Permeability; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoquinolines; Kinetics; Locus Coeruleus; Membrane Potentials; Neurons; Nystatin; Patch-Clamp Techniques; Piperazines; Potassium; Potassium Channel Blockers; Potassium Channels; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Thionucleotides; Yohimbine

1998
The expression of functional postsynaptic alpha2-adrenoceptors in the corpus cavernosum smooth muscle.
    British journal of pharmacology, 1998, Volume: 123, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Cyclic AMP; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Penis; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Synapses; Tritium; Yohimbine

1998
Alpha-adrenoceptor subtypes of dog saphenous vein: another unusual property.
    Life sciences, 1998, Volume: 62, Issue:17-18

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Dogs; Female; Fluorescence; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Signal Transduction; Yohimbine

1998
Prejunctional alpha2-adrenoceptors and peroxide-induced potentiation of norepinephrine release from the bovine iris.
    Neurochemical research, 1998, Volume: 23, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Brimonidine Tartrate; Cattle; Clonidine; Culture Techniques; Hydrogen Peroxide; Iris; Neuroeffector Junction; Norepinephrine; Oxymetazoline; Perfusion; Quinoxalines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Tritium; Yohimbine

1998
Non-NMDA and NMDA receptors in the synaptic pathway between area postrema and nucleus tractus solitarius.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Brain Stem; Cardiovascular System; Cerebral Ventricles; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Male; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synaptic Transmission; Yohimbine

1998
Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; CHO Cells; Cricetinae; Guanfacine; Humans; Idazoxan; Imidazoles; Ligands; Medetomidine; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Yohimbine

1998
Pharmacological evidence for different alpha 2-adrenergic receptor sites mediating analgesia and sedation in the rat.
    British journal of anaesthesia, 1998, Volume: 81, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics, Non-Narcotic; Animals; Brimonidine Tartrate; Clonidine; Conscious Sedation; Hypnotics and Sedatives; Imidazoles; Injections, Intraventricular; Injections, Spinal; Male; Medetomidine; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine

1998
A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis.
    Scanning microscopy, 1996, Volume: 10, Issue:1

    Topics: Brimonidine Tartrate; Calcium; Chlorides; Electron Probe Microanalysis; HT29 Cells; Humans; Intestinal Mucosa; Ion Transport; Quinoxalines; Receptors, Adrenergic, alpha-2; Sodium; Yohimbine

1996
Inhibition by midazolam of the adrenergic function in the isolated canine mesenteric vein.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Animals; Anti-Anxiety Agents; Brimonidine Tartrate; Calcium; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Female; Male; Mesenteric Veins; Midazolam; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Tetrodotoxin; Vasoconstrictor Agents; Vasodilator Agents; Yohimbine

1998
Insights into the unusual alpha adrenoceptor subtype in dog saphenous vein using phenoxybenzamine.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine

1999
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:1

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonidine Tartrate; Cell Count; Cell Survival; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Retinal Ganglion Cells; Timolol; Yohimbine

1999
Modulation of relative intrinsic activity of agonists at the alpha-2A adrenoceptor by mutation of residue 351 of G protein gi1alpha.
    Molecular pharmacology, 1999, Volume: 55, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; COS Cells; Cysteine; Dose-Response Relationship, Drug; Epinephrine; Glycine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Point Mutation; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Swine; Yohimbine

1999
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112 Suppl 1

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine

1998
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine

1999
Inhibitory effects of adrenaline on the release of noradrenaline from sympathetic nerves in human dental pulp.
    Archives of oral biology, 1999, Volume: 44, Issue:5

    Topics: Adolescent; Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Adult; Brimonidine Tartrate; Culture Techniques; Dental Pulp; Desipramine; Epinephrine; Humans; Norepinephrine; Quinoxalines; Radiopharmaceuticals; Receptors, Presynaptic; Sympathetic Nervous System; Tritium; Yohimbine

1999
Noradrenaline release from cultured mouse postganglionic sympathetic neurons: autoreceptor-mediated modulation.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Electric Stimulation; Ganglia, Sympathetic; Humans; Idazoxan; Kinetics; Mice; Mice, Inbred Strains; Neurons; Norepinephrine; Phenethylamines; Phentolamine; Purinergic P1 Receptor Agonists; Quinoxalines; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine

1999
Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Adrenergic Antagonists; Anesthesia; Aniline Compounds; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Femoral Artery; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Perfusion; Phenylephrine; Piperidines; Prazosin; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilator Agents; Yohimbine

1999
Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Cricetinae; Cysteine; Dopamine Antagonists; Humans; Idazoxan; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Protein Structure, Tertiary; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Sequence Homology, Amino Acid; Serine; Transfection; Tritium; Yohimbine

2000
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Gene Expression; Humans; Hydrogen-Ion Concentration; Imidazoles; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Tetrahydronaphthalenes; Yohimbine

2000
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Calcium; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Estrenes; Fluorescence; Gene Expression; Humans; Imidazoles; Norepinephrine; Prazosin; Pyrrolidinones; Quinoxalines; Radioligand Assay; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Tetrahydronaphthalenes; Thapsigargin; Xanthenes; Yohimbine

2000
Effect of brimonidine on rabbit trabecular meshwork hyaluronidase activity.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cyclic AMP; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Male; Quinoxalines; Rabbits; Radioimmunoassay; Trabecular Meshwork; Yohimbine

2000
Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Binding Sites; Brimonidine Tartrate; CHO Cells; Cricetinae; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Isoproterenol; Kinetics; Oxymetazoline; Pindolol; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin Antagonists; Signal Transduction; Swine; Yohimbine

2000
Food deprivation increases alpha(2)-adrenoceptor-mediated modulation of jejunal epithelial transport in young and adult rats.
    The Journal of nutrition, 2000, Volume: 130, Issue:10

    Topics: Animals; Biological Transport; Brimonidine Tartrate; Carrier Proteins; Electric Conductivity; Epithelium; Food Deprivation; Furosemide; Jejunum; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Tritium; Yohimbine

2000
alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Brimonidine Tartrate; Chromatography, Liquid; Electroretinography; Extracellular Space; Glutamic Acid; Ischemia; Male; Mass Spectrometry; Quinoxalines; Rats; Rats, Inbred BN; Retina; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body; Yohimbine

2001
Alpha2-adrenoceptor-mediated inhibition of cultured sympathetic neurons: changes in alpha2A/D-adrenoceptor-deficient mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Evoked Potentials; Female; Ganglia, Sympathetic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neurons; Norepinephrine; Pertussis Toxin; Phentolamine; Quinoxalines; Receptors, Adrenergic, alpha-2; Tritium; Virulence Factors, Bordetella; Yohimbine

2001
Postjunctional alpha(2C)-adrenoceptor contractility in human saphenous vein.
    European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Animals; Azepines; Brimonidine Tartrate; CHO Cells; Cricetinae; Dioxanes; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Vasoconstriction; Yohimbine

2001
[Modulatory action of alpha 2-adrenoceptor on calcitonin gene-related peptide release from rat mesenteric arterial bed].
    Sheng li xue bao : [Acta physiologica Sinica], 1998, Volume: 50, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcitonin Gene-Related Peptide; Endotoxins; In Vitro Techniques; Male; Mesenteric Arteries; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine

1998
The effect of adrenergic compounds on neurogenic dural vasodilatation.
    European journal of pharmacology, 2001, Jul-13, Volume: 424, Issue:1

    Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Dose-Response Relationship, Drug; Dura Mater; Electric Stimulation; Injections, Intravenous; Male; Phenylephrine; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation; Yohimbine

2001
Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.
    Brain research, 2001, Jun-15, Volume: 904, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds; Brimonidine Tartrate; Calbindin 2; Cell Death; Choline O-Acetyltransferase; Clonidine; Electroretinography; Heptanes; Imidazoline Receptors; Immunohistochemistry; Membrane Potentials; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reperfusion Injury; Retina; Retinal Ganglion Cells; S100 Calcium Binding Protein G; Yohimbine

2001
alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Blood Pressure; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Mydriasis; Piperidines; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vas Deferens; Vasodilator Agents; Yohimbine

2001
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
    British journal of pharmacology, 2001, Volume: 134, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine

2001
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
    European journal of pharmacology, 2001, Dec-07, Volume: 432, Issue:2-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine

2001
Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Atropine; Benzofurans; Brimonidine Tartrate; Dioxanes; Enzyme Inhibitors; Evoked Potentials; Female; Gastric Fundus; Gastrointestinal Agents; Humans; Male; Middle Aged; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Piperidines; Quinoxalines; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Receptors, Vasoactive Intestinal Peptide; Serotonin Antagonists; Stomach; Synaptic Transmission; Vasoactive Intestinal Peptide; Yohimbine

2002
Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Binding, Competitive; Brimonidine Tartrate; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Idazoxan; Middle Cerebral Artery; Norepinephrine; Phenylephrine; Pregnancy; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine

2002
Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Bridged-Ring Compounds; Brimonidine Tartrate; Buffers; Dose-Response Relationship, Drug; Heart; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indomethacin; Male; Norbornanes; Norepinephrine; Perfusion; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Thiocarbamates; Thiones; Yohimbine

2002
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Azepines; Brimonidine Tartrate; Clonidine; Idazoxan; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxazoles; Prostaglandins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Yohimbine

2002
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine

2003
Role of the alpha2-adrenoceptors on the pulmonary circulation in the ovine fetus.
    Pediatric research, 2003, Volume: 54, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Enzyme Inhibitors; Female; Gestational Age; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Pregnancy; Pulmonary Circulation; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Yohimbine

2003
Pharmacological evidence of a role for prejunctional imidazoline (I(1)) receptors in ocular function.
    Current eye research, 2002, Volume: 25, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Brimonidine Tartrate; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Imidazoline Receptors; Nictitating Membrane; Ocular Physiological Phenomena; Platelet Aggregation Inhibitors; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine

2002
Altered prejunctional modulation of intestinal cholinergic and noradrenergic pathways by alpha2-adrenoceptors in the presence of experimental colitis.
    British journal of pharmacology, 2003, Volume: 139, Issue:2

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Colitis; Colon; Dinitrofluorobenzene; Electric Stimulation; Enteric Nervous System; Gastrointestinal Motility; Gastrointestinal Transit; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; Yohimbine

2003
Norepinephrine activates extracellular-regulated kinase in cortical neurons.
    Biological psychiatry, 2003, Nov-15, Volume: 54, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Brimonidine Tartrate; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Extracellular Space; Female; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Neurons; Norepinephrine; Pertussis Toxin; Phosphorylation; Prazosin; Pregnancy; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine

2003
Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Bridged Bicyclo Compounds; Brimonidine Tartrate; Drug Synergism; Heart; Heptanes; Imidazoles; Imidazoline Receptors; Norepinephrine; Oxazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Sympatholytics; Yohimbine

2003
alpha2-Adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons.
    Brain research, 2004, Jul-16, Volume: 1014, Issue:1-2

    Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Clonidine; GTP-Binding Proteins; Neocortex; Norepinephrine; Patch-Clamp Techniques; Pertussis Toxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine

2004
Chronic morphine treatment reduces recovery from opioid desensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine

2004
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:3

    Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine

2004
Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor.
    Journal of neuroscience research, 2005, Mar-15, Volume: 79, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azides; Brimonidine Tartrate; Cell Membrane; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Polyacrylamide Gel; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pertussis Toxin; Phenoxybenzamine; Phosphorus Isotopes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tumor Necrosis Factor-alpha; Yohimbine

2005
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.
    Neuroscience, 2005, Volume: 133, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Northern; Brimonidine Tartrate; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; Gene Expression Regulation; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine

2005
Impairment of presynaptic alpha2-adrenoceptor-regulated norepinephrine overflow in failing hearts from Zucker diabetic fatty rats.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Body Weight; Brimonidine Tartrate; Diabetes Mellitus, Type 2; Electric Stimulation; Heart Failure; Heterozygote; Homozygote; Male; Norepinephrine; Organ Size; Perfusion; Quinoxalines; Rats; Rats, Zucker; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Yohimbine

2006
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
    European journal of pharmacology, 2006, Jul-10, Volume: 541, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine

2006
Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.
    Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Brimonidine Tartrate; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methoxamine; Nitric Oxide; Phenylephrine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin; Vasoconstrictor Agents; Vasodilation; Yohimbine

2006
Effects of brimonidine ingestion on cardiovascular responses and renal function in conscious dogs.
    Veterinary research communications, 2007, Volume: 31, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Brimonidine Tartrate; Cardiovascular System; Dogs; Drug Interactions; Electrocardiography; Electrolytes; Female; Glomerular Filtration Rate; Heart Rate; Kidney; Male; p-Aminohippuric Acid; Quinoxalines; Renal Plasma Flow, Effective; Respiration; Yohimbine

2007
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
    British journal of pharmacology, 2007, Volume: 151, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine

2007
Suprachiasmatic modulation of noradrenaline release in the ventrolateral preoptic nucleus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-13, Volume: 27, Issue:24

    Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; Preoptic Area; Quinoxalines; Rats; Suprachiasmatic Nucleus; Yohimbine

2007
The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Bile; Bile Duct Diseases; Bile Ducts, Intrahepatic; Brimonidine Tartrate; Chloride-Bicarbonate Antiporters; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Hepatocytes; Ligation; Liver; Male; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-2; Secretin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Yohimbine

2007
Noradrenergic vasoconstriction of pig prostatic small arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 376, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Arteries; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; In Vitro Techniques; Indoles; Male; Norepinephrine; Piperazines; Prazosin; Prostate; Quinoxalines; Swine; Thymine; Vasoconstriction; Yohimbine

2008
Noradrenergic and GABA B receptor activation differentially modulate inputs to the premotor nucleus RA in zebra finches.
    Journal of neurophysiology, 2008, Volume: 100, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Baclofen; Bicuculline; Brimonidine Tartrate; Electric Stimulation; Excitatory Postsynaptic Potentials; Finches; GABA Agonists; GABA Antagonists; In Vitro Techniques; Male; Models, Neurological; Neural Pathways; Neurons; Norepinephrine; Quinoxalines; Receptors, Adrenergic; Receptors, GABA-B; Telencephalon; Yohimbine

2008
Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jun-03, Volume: 29, Issue:22

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Biophysics; Brain; Brimonidine Tartrate; Buprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Methionine; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Transgenic; Naltrexone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Yohimbine

2009
Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned rats.
    Brain research, 2010, Apr-09, Volume: 1324

    Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Locus Coeruleus; Male; Medial Forebrain Bundle; Neurotoxins; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine

2010
Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 382, Issue:5-6

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Imidazoles; In Vitro Techniques; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Piperazines; Prazosin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Serotonin; Tail; Temperature; Vasoconstriction; Yohimbine

2010
A switch in the neuromodulatory effects of dopamine in the oval bed nucleus of the stria terminalis associated with cocaine self-administration in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jun-15, Volume: 31, Issue:24

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Patch-Clamp Techniques; Quinoxalines; Quinpirole; Rats; Rats, Long-Evans; Reinforcement Schedule; Self Administration; Septal Nuclei; Synaptic Potentials; Yohimbine

2011
Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes?
    Diabetologia, 2012, Volume: 55, Issue:11

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Brimonidine Tartrate; Calcium; Cells, Cultured; Diabetes Mellitus, Type 2; Diazoxide; Female; Hyperglycemia; Imidazoles; Insulin; Insulin-Secreting Cells; KATP Channels; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Quinoxalines; Yohimbine

2012
α2-adrenergic receptors in spiral ganglion neurons may mediate protective effects of brimonidine and yohimbine against glutamate and hydrogen peroxide toxicity.
    Neuroscience, 2013, Jan-03, Volume: 228

    Topics: Animals; Brimonidine Tartrate; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Hydrogen Peroxide; Neuroprotective Agents; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Spiral Ganglion; Yohimbine

2013
Contribution of α-adrenoceptor stimulation by phenylephrine to basal nitric oxide production in the isolated mouse aorta.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Yohimbine

2013
Multidimensional GPCR profiling and screening using impedance-based label-free and real-time assay.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1272

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Area Under Curve; Brimonidine Tartrate; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Drug Discovery; Electric Impedance; HeLa Cells; High-Throughput Screening Assays; Humans; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Signal Transduction; Yohimbine

2015
Neuropeptide Y as a presynaptic modulator of norepinephrine release from the sympathetic nerve fibers in the pig pineal gland.
    Polish journal of veterinary sciences, 2015, Volume: 18, Issue:1

    Topics: Adrenergic Fibers; Animals; Brimonidine Tartrate; Female; Neuropeptide Y; Norepinephrine; Pineal Gland; Quinoxalines; Swine; Yohimbine

2015
Both α
    Pharmacological reports : PR, 2021, Volume: 73, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Thymine; Yohimbine

2021