quinoxalines has been researched along with tirapazamine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González, M; Hamilton, E; López de Ceráin, A; Marín, A; Martínez-Crespo, FJ; Monge, A; Narro, S; Palop, JA; Sainz, Y; Senador, V | 1 |
| de Miguel, C; García, E; González, M; López de Ceráin, A; Martínez-Crespo, FJ; Monge, A; Narro, S; Palop, JA; Sainz, Y; Senador, V | 1 |
| Fuchs, T; Gates, KS; Greenberg, MM; Hwang, JT | 1 |
| Chignell, CF; Inbaraj, JJ; Motten, AG | 1 |
| Hori, H; Kinashi, Y; Masunaga, S; Nagasawa, H; Nagata, K; Ohnishi, K; Ohnishi, T; Ono, K; Suzuki, M; Takahashi, A; Uto, Y | 1 |
| Hori, H; Kinashi, Y; Masunaga, S; Nagasawa, H; Nagata, K; Ono, K; Suzuki, M; Uto, Y | 1 |
| Arbillaga, L; de Cerain, AL; Gates, KS; Junnotula, V; Monge, A; Rajapakse, A; Solano, B; Villar, R | 1 |
| Beavers, CM; El-Khatib, M; Farber, KM; Fettinger, JC; Haddadin, MJ; Kurth, MJ; Olmstead, MM; Shoker, TA | 1 |
| Chopra, S; Doppalapudi, RS; Franzblau, SG; Green, CE; Iyer, LV; Koolpe, GA; Madrid, PB; Matsuyama, KN; Riccio, ES; Ryan, KJ; Tambo-Ong, AA; Tran, TB; Wan, B | 1 |
| Anderson, RF; Denny, WA; Hay, MP; Marshall, AJ; Reynisson, J; Yadav, P | 1 |
| Cheng, G; Dai, M; Hao, H; Li, B; Liang, G; Liu, Z; Wang, C; Wang, X; Wang, Y; Weng, Z; Yuan, Z; Zhang, H | 1 |
11 other study(ies) available for quinoxalines and tirapazamine
| Article | Year |
|---|---|
Hypoxia-selective agents derived from 2-quinoxalinecarbonitrile 1,4-di-N-oxides. 2.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Lung; Molecular Structure; Quinoxalines; Tirapazamine; Triazines | 1995 |
Hypoxia-selective agents derived from quinoxaline 1,4-di-N-oxides.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Mice; Mice, Inbred BALB C; Quinoxalines; Tirapazamine; Triazines; Tumor Cells, Cultured | 1995 |
Photosensitization of guanine-specific DNA damage by a cyano-substituted quinoxaline di-N-oxide.
Topics: Antineoplastic Agents; Base Sequence; DNA; DNA Damage; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Sequence Data; Photosensitizing Agents; Quinoxalines; Radiation-Sensitizing Agents; Tirapazamine; Triazines; Ultraviolet Rays | 1999 |
Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues.
Topics: Antineoplastic Agents; Azides; Computer Simulation; Cyclic N-Oxides; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; NAD; Oxidation-Reduction; Photolysis; Plasmids; Quinoxalines; Radiation-Sensitizing Agents; Singlet Oxygen; Spectrophotometry; Spin Labels; Tirapazamine; Triazines | 2003 |
Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Cyclic N-Oxides; Gamma Rays; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Micronucleus Tests; Mutation; Organophosphorus Compounds; Quinoxalines; Radiotherapy; Tirapazamine; Triazines; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2005 |
The usefulness of continuous administration of hypoxic cytotoxin combined with mild temperature hyperthermia, with reference to effects on quiescent tumour cell populations.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclic N-Oxides; Female; Fluorescent Antibody Technique; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Neoplasms; Quinoxalines; Tirapazamine; Triazines | 2005 |
DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; DNA; DNA Cleavage; Humans; Hypoxia; Molecular Structure; NADP; Oxidation-Reduction; Quinoxalines; Tirapazamine; Triazines | 2010 |
Quinoxalino[2,3-c]cinnolines and their 5-N-oxide: alkoxylation of methyl-substituted quinoxalino[2,3-c]cinnolines to acetals and orthoesters.
Topics: Acetals; Alcohols; Antineoplastic Agents; Benzoxazoles; Chemistry, Pharmaceutical; Cyanides; Cyclization; Esters; Heterocyclic Compounds, 2-Ring; Humans; Magnetic Resonance Spectroscopy; Neoplasms; Oxides; Quinoxalines; Tirapazamine; Triazines | 2011 |
Discovery and optimization of benzotriazine di-N-oxides targeting replicating and nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Female; Isomerism; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrofurans; Nitroimidazoles; Oxides; Quinoxalines; Rats; Tirapazamine; Triazines; Tuberculosis; Vero Cells | 2012 |
Fragmentation of the quinoxaline N-oxide bond to the ˙OH radical upon one-electron bioreduction.
Topics: Antineoplastic Agents; Humans; Hydroxyl Radical; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxides; Pyrroles; Quinoxalines; Tirapazamine; Triazines | 2014 |
Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.
Topics: Anti-Bacterial Agents; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Annotation; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Proteomics; Quinoxalines; Reactive Oxygen Species; SOS Response, Genetics; Structure-Activity Relationship; Tirapazamine; Triazines | 2015 |