quinoxalines has been researched along with sildenafil citrate in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 26 (92.86) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurowski, S; Vemulapalli, S | 1 |
| Ikeo, T; Inoue, H; Kikkawa, K; Mochida, H; Noto, T; Takagi, M; Yano, K | 1 |
| Buvinic, S; Huidobro-Toro, JP | 1 |
| Adler-Graschinsky, E; Boric, MP; Figueroa, XF; Huidobro-Toro, JP; Mendizábal, VE; Poblete, MI | 1 |
| Crescioli, C; Fazzini, A; Filippi, S; Ledda, F; Maggi, M; Natali, A; Riffaud, JP; Vannelli, GB | 1 |
| Goldstein, I; Jeong, SJ; Kim, NN; Kim, SW; Munarriz, R; Traish, AM | 1 |
| Antunes, E; Baracat, JS; De Nucci, G; de Oliveira, JF; Fregonesi, A; Okuyama, CE; Priviero, FB; Rodrigues Netto, N; Teixeira, CE | 1 |
| Fu, J; Liu, WJ; Tian, L; Wang, LL; Xin, ZC; Yuan, YM | 1 |
| Andersen, CU; Mulvany, MJ; Simonsen, U | 1 |
| Ambriz-Tututi, M; Granados-Soto, V; Urquiza-Marín, H; Velázquez-Zamora, DA | 1 |
| Altura, BM; Altura, BT; Li, J; Li, W | 1 |
| Angelini, GD; Jeremy, JY; Jones, R; Persad, R; Shukla, N | 1 |
| Angelini, GD; Jeremy, JY; Muzaffar, S; Shukla, N; Srivastava, A | 1 |
| Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE | 1 |
| Birk, S; Edvinsson, L; Engel, U; Khurana, TS; Kruuse, C; Olesen, J; Rybalkin, SD | 1 |
| Araiza-Saldaña, CI; Bermúdez-Ocaña, DY; Granados-Soto, V; Pérez-Severiano, F; Reyes-García, G | 1 |
| Alborch, E; Burguete, MC; Castelló-Ruiz, M; Pérez-Asensio, FJ; Salom, JB; Torregrosa, G | 1 |
| Priviero, FB; Teixeira, CE; Todd, J; Webb, RC | 1 |
| Allanson, M; Domanski, D; Reeve, VE | 1 |
| Adaikan, PG; Lau, LC | 1 |
| Eltze, M; Grebe, T; Hatzelmann, A; Klein, T; Kömhoff, M | 1 |
| Cavalcante, IF; Ribeiro, RA; Rolim, DE; Souza, MH; Vale, ML | 1 |
| Dunkern, TR; Feurstein, D; Hatzelmann, A; Rossi, GA; Sabatini, F | 1 |
| Brito, GA; Gadelha, GG; Garcia, JA; Lima, SJ; Medeiros, JV; Ribeiro, RA; Santos, AA; Soares, PM; Souza, MH | 1 |
| Brock, SC; Tonussi, CR | 1 |
| Antunes, E; Priviero, FB; Teixeira, CE; Toque, HA; Webb, RC; Zemse, SM | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Dinc, B; Karasu, E; Kayacan, N; Sadan, G | 1 |
28 other study(ies) available for quinoxalines and sildenafil citrate
| Article | Year |
|---|---|
Sildenafil relaxes rabbit clitoral corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Clitoris; Electric Stimulation; Female; Guanylate Cyclase; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Sildenafil Citrate; Sulfones; Synaptic Transmission; Tetrodotoxin | 2000 |
Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Papaverine; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Pyridines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetrodotoxin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Basal tonic release of nitric oxide coupled to cGMP production regulates the vascular reactivity of the mesenteric bed.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Norepinephrine; Oxadiazoles; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine | 2001 |
Effects of NCX 4050, a new NO donor, in rabbit and human corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Penile Erection; Penis; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rabbits; Sildenafil Citrate; Sulfones | 2003 |
Role of the nitric oxide-cyclic GMP pathway in regulation of vaginal blood flow.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Female; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Regional Blood Flow; Sexual Behavior, Animal; Sildenafil Citrate; Sulfones; Vagina | 2003 |
Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.
Topics: Adolescent; Adult; Child; Cyclic GMP; Drug Evaluation, Preclinical; Electric Stimulation; Enzyme Inhibitors; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penis; Phenylephrine; Piperazines; Priapism; Purines; Quinoxalines; Scorpion Venoms; Second Messenger Systems; Sildenafil Citrate; Sodium Channel Blockers; Sulfones; Tetrodotoxin | 2004 |
[Effects of icariin on intracavernosal pressure and systematic arterial blood pressure of rat].
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Flavonoids; Nitroarginine; Oxadiazoles; Papaverine; Penile Erection; Piperazines; Pressure; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones | 2004 |
Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats.
Topics: Acetylcholine; Actins; Animals; Atrial Natriuretic Factor; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Guanylate Cyclase; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Lung; Male; Molsidomine; Muscle, Smooth; Oxadiazoles; Piperazines; Pulmonary Artery; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Systole; Vasodilation; Vasodilator Agents | 2005 |
Analysis of the mechanism underlying the peripheral antinociceptive action of sildenafil in the formalin test.
Topics: Analgesics; Animals; Apamin; Charybdotoxin; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Injections, Subcutaneous; Oxadiazoles; Pain; Pain Measurement; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetraethylammonium; Time Factors; Tolbutamide | 2005 |
Peroxynitrite-induced relaxation in isolated rat aortic rings and mechanisms of action.
Topics: Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; In Vitro Techniques; Male; Marine Toxins; Methylene Blue; Oxadiazoles; Oxazoles; Peroxynitrous Acid; Phenylephrine; Piperazines; Potassium; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2005 |
Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits.
Topics: Acetophenones; Allopurinol; Animals; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypercholesterolemia; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Onium Compounds; Oxadiazoles; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Rotenone; Sildenafil Citrate; Sulfones; Superoxides; Uncoupling Agents; Xanthine Oxidase | 2005 |
Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Cyclic GMP; Endothelial Cells; Guanylate Cyclase; Male; Membrane Glycoproteins; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxadiazoles; Piperazines; Protein Kinase Inhibitors; Pulmonary Artery; Purines; Quinoxalines; Sildenafil Citrate; Sulfones; Superoxides; Swine; Thionucleotides | 2005 |
Mechanisms underlying relaxation of rabbit aorta by BAY 41-2272, a nitric oxide-independent soluble guanylate cyclase activator.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Pyrazoles; Pyridines; Quinoxalines; Rabbits; Signal Transduction; Sildenafil Citrate; Sulfones; Vasodilation | 2005 |
Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aged; Aged, 80 and over; Animals; Basilar Artery; Blotting, Western; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Guinea Pigs; Humans; Hydrolysis; In Vitro Techniques; Infant; Male; Morpholines; Muscle, Smooth, Vascular; Nitroprusside; Oxadiazoles; Piperazines; Purines; Pyrazoles; Pyrimidines; Pyrimidinones; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2005 |
Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
Topics: Analgesia; Animals; Blood Glucose; Body Weight; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Streptozocin; Sulfones; Time Factors | 2005 |
Relaxant effect of sildenafil in the rabbit basilar artery.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Basilar Artery; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rabbits; Signal Transduction; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2006 |
Vasorelaxing effect of BAY 41-2272 in rat basilar artery: involvement of cGMP-dependent and independent mechanisms.
Topics: Animals; Basilar Artery; Brain Stem; Calcium Chloride; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Ouabain; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Photoimmunoprotection by UVA (320-400 nm) radiation is determined by UVA dose and is associated with cutaneous cyclic guanosine monophosphate.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Dermatitis, Contact; Dose-Response Relationship, Radiation; Enzyme Activation; Female; Guanylate Cyclase; Immune Tolerance; Mice; Mice, Inbred Strains; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Sildenafil Citrate; Skin; Sulfones; Ultraviolet Rays | 2006 |
Mechanisms of direct relaxant effect of sildenafil, tadalafil and vardenafil on corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium; Carbolines; Dose-Response Relationship, Drug; Imidazoles; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Oxadiazoles; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Verapamil | 2006 |
Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Celecoxib; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Perfusion; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Purinones; Pyrazoles; Quinoxalines; Rats; Regional Blood Flow; Signal Transduction; Sildenafil Citrate; Sulfonamides; Sulfones; Vasodilator Agents | 2007 |
Role of NO/cGMP/KATP pathway in antinociceptive effect of sildenafil in zymosan writhing response in mice.
Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Piperazines; Potassium Channels; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones; Zymosan | 2007 |
Inhibition of TGF-beta induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase.
Topics: Actins; Benzamides; Benzoates; Blotting, Western; Cell Differentiation; Cells, Cultured; Cyclic GMP; Dinoprostone; Drug Synergism; Enzyme Activators; Fibroblasts; Fibrosis; Guanylate Cyclase; Humans; Immunohistochemistry; Isoenzymes; Lung; Myocytes, Smooth Muscle; Natriuretic Peptide, Brain; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyridines; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfones; Transforming Growth Factor beta | 2007 |
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
Intrathecally injected morphine inhibits inflammatory paw edema: the involvement of nitric oxide and cyclic-guanosine monophosphate.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Neutrophil Infiltration; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Peroxidase; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sildenafil Citrate; Spinal Cord; Sulfones; Time Factors | 2008 |
Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects.
Topics: Animals; Carbolines; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanylate Cyclase; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroglycerin; Oxadiazoles; Penile Erection; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents | 2009 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Endothelial dysfunction in the human umbilical artery due to preeclampsia can be prevented by sildenafil.
Topics: Adolescent; Adult; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperazines; Pre-Eclampsia; Pregnancy; Purines; Quinoxalines; Sildenafil Citrate; Sulfones; Umbilical Arteries; Vasodilation; Vasodilator Agents; Young Adult | 2012 |