quinoxalines has been researched along with sb 525334 in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 20 (64.52) | 24.3611 |
| 2020's | 9 (29.03) | 2.80 |
| Authors | Studies |
|---|---|
| Burgert, M; Cadacio, C; Everitt, JI; Frazier, KS; Gold, LI; Laping, NJ; Portis, MJ; Walker, CL | 1 |
| Beach, S; Budd, DC; Crosby, A; Davies, RJ; Docx, C; Duggan, N; England, K; Holmes, AM; Leblanc, C; Lebret, C; Morrell, NW; Raza, F; Schindler, F; Thomas, M; Walker, C | 1 |
| Asencio, C; Génot, E; Le Roux-Goglin, E; Mégraud, F; Spuul, P; Varon, C | 1 |
| Bae, I; Hong, YB; Hwang, JS; Kim, YJ; Seong, YS | 1 |
| Alexander, R; Blanchard, A; Chambers, RC; Datta, A; Forty, EJ; Hayes, B; Mercer, PF; Scotton, CJ | 1 |
| Allard, J; Bauer, CM; Bitter, H; Budd, DC; Burns, L; Chen, L; Fine, JS; Garrido, R; Harris, P; Hogaboam, CM; Kitson, C; Liang, Z; Peng, R; Phillips, JE; Ravindran, P; Renteria, L; Sridhar, S; Stevenson, CS; Tyagi, G; Woods, J | 1 |
| D'Amore, PA; dela Paz, NG; Walshe, TE | 1 |
| Aaron, KJ; Sanders, PW; Ying, WZ | 1 |
| Baker, AH; Denby, L; McBride, M; Ramdas, V | 1 |
| Aurora, AB; Baker, AH; Conway, BR; Delles, C; Denby, L; Dickinson, B; Grant, JS; Kipgen, D; Lu, R; McClure, JD; Ramdas, V; van Rooij, E | 1 |
| Cong, L; Xia, ZK; Yang, RY | 1 |
| Fan, C; Hu, X; Jin, C; Liu, Y; Lu, X; Tao, H; Wang, X; Zhu, Y | 1 |
| Hu, X; Jin, C; Liu, Y; Lu, X; Tao, H; Wang, X; Zhu, Y | 1 |
| Imada, K; Inokuchi, J; Itsumi, M; Kuruma, H; Naito, S; Oda, Y; Shiota, M; Takeuchi, A; Tatsugami, K; Uchiumi, T; Yokomizo, A | 1 |
| Abrigo, J; Cabello-Verrugio, C; Cabrera, D; Di Capua, G; Morales, MG; Simon, F | 1 |
| Chen, X; Fang, H; Hou, J; Wu, X; Xu, F; Yin, S; Zhang, J; Zhang, X | 1 |
| Aimaiti, Y; Feng, Y; Jin, X; Li, D; Mao, X; Wang, W | 1 |
| Harasymczuk, J; Jagodziński, PP; Jakub, G; Lehmann, TP | 1 |
| Bajaj, A; Decker-Rockefeller, B; Li, QF; Pumiglia, K | 1 |
| Ammar, R; Cai, H; Huang, X; Jarai, G; Ravi, K; Thompson, J; Wang, Y; Zhang, Y | 1 |
| Brandan, E; Contreras, O; Faundez-Contreras, J; González, D; Lipson, KE; Murphy-Ullrich, JE; Rebolledo, DL; Vio, CP | 1 |
| Banjanac, M; Belamarić, D; Bosnar, M; Cedilak, M; Čužić, S; Eraković Haber, V; Faraho, I; Glojnarić, I; Ilić, K; Paravić Radičević, A | 1 |
| He, J; Leng, Z; Li, M; Qian, M; Wen, H; Yu, Q | 1 |
| Cao, H; Gao, M; Jin, M; Skolnick, J; Tao, YJ; Zhou, H | 1 |
| Chen, L; Cheng, S; Li, B; Lin, Z; Wang, M; Wang, W; Yao, M; Yin, Q; Zhang, Y | 1 |
| Ito, S; Kimura, K; Okuda, K; Yamamoto, Y | 1 |
| Aoyama, T; Sakai, M; Sumiyoshi, T; Urayama, K; Yoshimura, R | 1 |
| Sakai, M; Yoshimura, R | 1 |
| Chen, X; Hou, J; Jiang, H; Liao, Y; Liao, Z; Liu, P; Wang, E; Wang, L; Wang, X; Wu, X; Xu, X | 1 |
| Basta, MD; Paulson, H; Walker, JL | 1 |
| Gotoh, S; Hagiwara, M; Hirai, T; Kanagaki, S; Masui, A; Mikawa, R; Moriguchi, K; Murakami, K; Nakao, K; Suezawa, T; Tamai, K; Toyomoto, M | 1 |
1 review(s) available for quinoxalines and sb 525334
| Article | Year |
|---|---|
The effect of Echinococcus granulosus on spleen cells and TGF-β expression in the peripheral blood of BALB/c mice.
Topics: Animals; Echinococcosis; Echinococcus granulosus; Female; Imidazoles; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Protein Serine-Threonine Kinases; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Spleen; T-Lymphocytes; Transforming Growth Factor beta | 2017 |
30 other study(ies) available for quinoxalines and sb 525334
| Article | Year |
|---|---|
Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats.
Topics: Activin Receptors, Type I; Animals; Apoptosis; Carcinoma, Renal Cell; Female; Imidazoles; Kidney Neoplasms; Leiomyoma; Mitosis; Protein Serine-Threonine Kinases; Quinoxalines; Rats; Rats, Inbred Strains; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta; Uterine Neoplasms | 2007 |
Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrot
Topics: Animals; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Cell Proliferation; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; Monocrotaline; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pulmonary Artery; Quinoxalines; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Smad3 Protein; Transforming Growth Factor beta1 | 2009 |
Helicobacter infection induces podosome assembly in primary hepatocytes in vitro.
Topics: Actin Cytoskeleton; Animals; Benzamides; Cell Line, Tumor; Dioxoles; Helicobacter Infections; Helicobacter pylori; Hepatocytes; Humans; Imidazoles; Liver; Mice; Primary Cell Culture; Quinoxalines; Transforming Growth Factor beta | 2012 |
Transforming growth factor beta receptor I inhibitor sensitizes drug-resistant pancreatic cancer cells to gemcitabine.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Humans; Imidazoles; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta | 2012 |
Ex vivo micro-computed tomography analysis of bleomycin-induced lung fibrosis for preclinical drug evaluation.
Topics: Animals; Bleomycin; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Fibrosis; Humans; Imidazoles; Lung; Male; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Treatment Outcome; X-Ray Microtomography | 2013 |
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease.
Topics: Airway Remodeling; Animals; Antibiotics, Antineoplastic; Bleomycin; Cluster Analysis; Disease Models, Animal; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Humans; Idiopathic Pulmonary Fibrosis; Imidazoles; Inflammation; Lung; Male; Mice; Mitosis; Protein Serine-Threonine Kinases; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction | 2013 |
The role of shear-induced transforming growth factor-β signaling in the endothelium.
Topics: Apoptosis; Endothelium, Vascular; Hemodynamics; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Kruppel-Like Transcription Factors; Nitric Oxide; Protein Serine-Threonine Kinases; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Stress, Mechanical; Transforming Growth Factor beta3 | 2013 |
Transforming growth factor-β regulates endothelial function during high salt intake in rats.
Topics: Animals; Aorta; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type III; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinoxalines; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2013 |
Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29.
Topics: Animals; Cell Line; Disintegrins; Fibrosis; Gene Expression Regulation, Enzymologic; Glomerulonephritis; Imidazoles; Male; Mice; MicroRNAs; Quinoxalines; Rats; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2013 |
MicroRNA-214 antagonism protects against renal fibrosis.
Topics: Animals; Disease Models, Animal; Fibrosis; Gene Deletion; Gene Expression; Humans; Imidazoles; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Quinoxalines; Renal Insufficiency, Chronic; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ureteral Obstruction | 2014 |
Targeting the TGF-β receptor with kinase inhibitors for scleroderma therapy.
Topics: Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Molecular Targeted Therapy; Morpholines; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quinolines; Quinoxalines; Receptors, Transforming Growth Factor beta; Scleroderma, Systemic | 2014 |
Interaction of ERK1/2 and Smad2/3 signaling pathways in TGF-β1-induced TIMP-3 expression in rat chondrocytes.
Topics: Animals; Cells, Cultured; Chondrocytes; Enzyme Activation; Flavonoids; Imidazoles; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrroles; Quinoxalines; Rats; Smad2 Protein; Smad3 Protein; Tissue Inhibitor of Metalloproteinase-3; Transforming Growth Factor beta1; Up-Regulation | 2014 |
Transforming growth factor-β1 induces type II collagen and aggrecan expression via activation of extracellular signal-regulated kinase 1/2 and Smad2/3 signaling pathways.
Topics: Aggrecans; Animals; Cartilage, Articular; Chondrocytes; Collagen Type II; Enzyme Activation; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Primary Cell Culture; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2015 |
Crosstalk between epithelial-mesenchymal transition and castration resistance mediated by Twist1/AR signaling in prostate cancer.
Topics: Adenocarcinoma; Androgens; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Combined Modality Therapy; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nuclear Proteins; Orchiectomy; Prostatic Neoplasms; Quinoxalines; Random Allocation; Receptors, Androgen; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta; Twist-Related Protein 1; Xenograft Model Antitumor Assays | 2015 |
Apocynin inhibits the upregulation of TGF-β1 expression and ROS production induced by TGF-β in skeletal muscle cells.
Topics: Acetophenones; Animals; Benzophenanthridines; Cell Line; Imidazoles; Mice; Muscle Fibers, Skeletal; Protein Kinase C; Quinoxalines; Reactive Oxygen Species; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2015 |
TGFβ signaling controls intrahepatic bile duct development may through regulating the Jagged1-Notch-Sox9 signaling axis.
Topics: Actins; Animals; Bile Ducts, Intrahepatic; Cells, Cultured; Epithelial Cells; Hepatocytes; Imidazoles; Jagged-1 Protein; Mesoderm; Mice; Myofibroblasts; Quinoxalines; Receptors, Notch; Signal Transduction; SOX9 Transcription Factor; Transforming Growth Factor beta | 2018 |
Transforming growth factor β mediates communication of co-cultured human nucleus pulposus cells and mesenchymal stem cells.
Topics: Adolescent; Benzamides; Cells, Cultured; Coculture Techniques; Collagen Type I; Collagen Type I, alpha 1 Chain; Dioxoles; Humans; Imidazoles; Mesenchymal Stem Cells; MicroRNAs; Nucleus Pulposus; Paracrine Communication; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; SOX9 Transcription Factor; Transforming Growth Factor beta | 2018 |
Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke.
Topics: Activin Receptors, Type II; Animals; Brain; Cells, Cultured; Endothelial Cells; Female; Fluorescent Antibody Technique; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Transgenic; Pericytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Vascular Malformations | 2018 |
Molecular characterization of a precision-cut rat liver slice model for the evaluation of antifibrotic compounds.
Topics: Animals; Biomarkers; Collagen Type I; Imidazoles; Indoles; Liver; Liver Cirrhosis; Male; Quinoxalines; Rats, Sprague-Dawley | 2019 |
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β.
Topics: Animals; Antibodies, Monoclonal, Humanized; Benzamides; Connective Tissue Growth Factor; Dioxoles; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Imidazoles; Male; Mice; Models, Animal; Muscle Denervation; Muscle, Skeletal; Quinoxalines; Signal Transduction; Transforming Growth Factor beta | 2019 |
Precision-cut lung slices from bleomycin treated animals as a model for testing potential therapies for idiopathic pulmonary fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Idiopathic Pulmonary Fibrosis; Imidazoles; Indoles; Lung; Male; Mice; Mice, Inbred C57BL; Quinoxalines | 2019 |
Inhibiting of self-renewal, migration and invasion of ovarian cancer stem cells by blocking TGF-β pathway.
Topics: Cadherins; Cell Line, Tumor; Cell Movement; Cell Self Renewal; Epithelial-Mesenchymal Transition; Female; Humans; Imidazoles; Neoplasm Invasiveness; Neoplastic Stem Cells; Ovarian Neoplasms; Phosphorylation; Quinoxalines; RNA, Messenger; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Vimentin | 2020 |
Differential kinase activity of ACVR1 G328V and R206H mutations with implications to possible TβRI cross-talk in diffuse intrinsic pontine glioma.
Topics: Activin Receptors, Type I; Benzazepines; Brain Stem Neoplasms; Cell Line, Tumor; Diffuse Intrinsic Pontine Glioma; Dose-Response Relationship, Drug; Humans; Imidazoles; Mutation; Panobinostat; Phosphotransferases; Prognosis; Protein Conformation; Pyrimidines; Quinoxalines; Receptor Cross-Talk; Receptors, Transforming Growth Factor beta | 2020 |
Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma.
Topics: Animals; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glycine; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Indazoles; Microwaves; Osteosarcoma; Quinoxalines; Rabbits; Radiofrequency Ablation; Transforming Growth Factor beta1; Tumor Burden | 2020 |
Involvement of activin signal pathway in cyclic apoptosis of the oviductal isthmic epithelium in cows.
Topics: Activin Receptors; Activins; Animals; Apoptosis; bcl-2-Associated X Protein; Benzamides; Cattle; Dioxoles; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Gene Expression Regulation; Imidazoles; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; RNA, Messenger; Signal Transduction | 2020 |
GPR91 antagonist and TGF-β inhibitor suppressed collagen production of high glucose and succinate induced HSC activation.
Topics: Animals; Cells, Cultured; Collagen; Glucose; Hepatic Stellate Cells; Imidazoles; Liver Cirrhosis; Male; Quinoxalines; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Succinic Acid; Transforming Growth Factor beta | 2020 |
Mechanotransduction-Targeting Drugs Attenuate Stiffness-Induced Hepatic Stellate Cell Activation in Vitro.
Topics: Actins; Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; Colchicine; Collagen Type I; Hepatic Stellate Cells; Imidazoles; Integrins; Male; Mechanotransduction, Cellular; Paclitaxel; Piperazines; Pyrazines; Quinoxalines; Rats, Sprague-Dawley; Roscovitine; Sulfonamides; Transforming Growth Factor beta; Tubulin Modulators | 2021 |
A combination of pirfenidone and TGF-β inhibition mitigates cystic echinococcosis-associated hepatic injury.
Topics: Animals; Echinococcosis, Hepatic; Imidazoles; Liver; Mice; Pyridones; Quinoxalines; Transforming Growth Factor beta1 | 2021 |
The local wound environment is a key determinant of the outcome of TGFβ signaling on the fibrotic response of CD44
Topics: Actins; Animals; Blotting, Western; Capsule Opacification; Cataract Extraction; Cell Proliferation; Chick Embryo; Collagen Type I; Disease Models, Animal; Fibronectins; Fibrosis; Hyaluronan Receptors; Imidazoles; Integrin alphaVbeta3; Microscopy, Fluorescence; Myofibroblasts; Posterior Capsule of the Lens; Postoperative Complications; Pyrazoles; Pyrroles; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Transforming Growth Factor beta; Wound Healing | 2021 |
Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids.
Topics: Alveolar Epithelial Cells; Bleomycin; Cell Differentiation; Cellular Senescence; Fibroblasts; Humans; Imidazoles; Induced Pluripotent Stem Cells; Models, Biological; Organoids; Pulmonary Fibrosis; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Transforming Growth Factor beta1 | 2021 |