Compounds > quinoxalines
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quinoxalines and rx 821002

quinoxalines has been researched along with rx 821002 in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.85)18.7374
1990's41 (75.93)18.2507
2000's9 (16.67)29.6817
2010's3 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paris, H; Remaury, A1
Dieudonne, MN; Giudicelli, Y; Pecquery, R1
Daviaud, D; Denis-Pouxviel, C; Devedjian, JC; Fargues, M; Paris, H; Prats, H1
Atgie, C; Carpene, C; Lafontan, M; Quideau, N; Saulnier-Blache, JS1
Lafontan, M; Langin, D; Paris, H1
Dauzats, M; Lafontan, M; Langin, D; Paris, H1
Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D1
Carpéné, C; Dauzats, M; Lafontan, M; Larrouy, D; Quideau, N; Saulnier-Blache, JS1
Berlan, M; Galitzky, J; Lafontan, M; Montastruc, JL; Senard, JM; Stillings, M1
Carpéné, C; Guichard, C; Lafontan, M; Lavau, M; Rebourcet, MC1
Carpéné, C; Lafontan, M; Langin, D; Saulnier-Blache, JS1
Advenier, C; Biyah, K1
Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG1
Bouloumie, A; Galitzky, J; Lafontan, M; Langin, D; Remaury, A; Tavernier, G; Valet, P1
Szabo, B; Urban, R1
García-Sevilla, JA; Garro, MA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L1
Musgrave, IF; Seifert, R1
Etgen, AM; Karkanias, GB1
García-Sevilla, JA; Sastre, M1
Bouloumié, A; Devedjian, JC; Lafontan, M; Planat, V; Record, M; Saulnier-Blache, JS; Valet, P1
Berlan, M; Galitzky, J; Le Corre, P; Le Verge, R1
Couvineau, A; Daviaud, D; Denis, C; Devedjian, JC; Drean, G; Planat, V; Salomon, R; Senard, JM; Valet, P; Voisin, T1
Daviaud, D; Larrouy, D; Paris, H; Remaury, A; Rouot, B1
Asier Garro, M; García-Sevilla, JA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L1
García-Sevilla, JA; Miralles, A; Ribas, C1
Starke, K; Trendelenburg, AU; Wahl, CA1
Flügge, G1
Intengan, HD; Smyth, DD1
Autissier, N; Beltramo, JL; Ben Cheikh, R; Chomard, P; Dumas, P1
Bétuing, S; Daviaud, D; Hickson, G; Lafontan, M; Lapalu, S; Peyroulan, D; Saulnier-Blache, JS; Valet, P1
Coupar, IM; Liu, L1
Elliott, J1
Goldstein, I; Huang, YH; Moreland, RB; Traish, AM1
Correze, C; Dib, K; el Jamali, A; Lambert, B; Wrisez, F1
Callado, LF; García-Sevilla, JA; Grijalba, B; Meana, JJ; Pazos, A; Sastre, M1
Barbe, P; Daviaud, D; Jeanneton, O; Lafontan, M; Pagès, C; Record, M; Saulnier-Blache, JS; Valet, P1
Escribá, PV; García-Sevilla, JA; Miralles, A; Ribas, C1
Audinot, V; Chaput, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Richard, N; Touzard, M; Verrièle, L1
Cayla, C; Gales, C; Paris, H; Quinchon, F; Roquelaine, C; Schaak, S1
Colpaert, FC; Pauwels, PJ; Wurch, T1
Mateo, Y; Meana, JJ1
Hall, L; Hudson, AL; Jackson, HC; Nutt, DJ; Robinson, ES1
Cockcroft, V; Frang, H; Marjamäki, A; Pihlavisto, M; Scheinin, M1
Bylund, DB; Happe, HK; Murrin, LC1
Colpaert, FC; Finana, F; Pauwels, PJ; Tardif, S; Wurch, T1
Bosch, F; Casellas, A; Cayla, C; Devedjian, JC; George, M; Paris, H; Pujol, A1
Busquets, X; García-Sevilla, JA; Miralles, A; Ribas, C1
Bylund, DB; Gerety, ME; Happe, HK; Murrin, LC1
Cistarelli, L; Di Cara, B; Gobert, A; Millan, MJ1
Hoffrén, AM; Johnson, MS; Kanerva, L; Marjamäki, A; Nyrönen, T; Peltonen, JM; Pihlavisto, M; Savola, JM; Scheinin, M; Wurster, S; Xhaard, H1
Bai, A; Chen, J; Guo, Y; Liu, Z; Lu, N1
Alba-Delgado, C; Berrocoso, E; Borges, G; Horrillo, I; Meana, JJ; Mico, JA; Neto, F; Ortega, JE; Sánchez-Blázquez, P1
Aono, Y; Cools, AR; Koshikawa, N; Saigusa, T; Takada, K; Uchida, T; Verheij, MM1
Álvarez de La Rosa, D; Arce-Franco, M; Armas-González, E; Barreiro, O; Díaz-González, F; Domínguez-Luis, MJ; Feria, M; Herrera-García, AM; Machado, JD; Pec, MK; Sánchez-Madrid, F1

Other Studies

54 other study(ies) available for quinoxalines and rx 821002

ArticleYear
The insulin-secreting cell line, RINm5F, expresses an alpha-2D adrenoceptor and nonadrenergic idazoxan-binding sites.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Cell Line; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Idazoxan; Immunoblotting; Insulin; Insulin Secretion; Kinetics; Membranes; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tritium; Virulence Factors, Bordetella; Yohimbine

1992
Characteristics of the alpha 2/beta-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites.
    European journal of biochemistry, 1992, Apr-15, Volume: 205, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cricetinae; Dioxanes; Epididymis; Epinephrine; GTP-Binding Proteins; Idazoxan; Isoproterenol; Kinetics; Lipolysis; Macromolecular Substances; Male; Mesocricetus; Organ Specificity; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Theophylline

1992
Regulation of the alpha 2A-adrenergic receptor in the HT29 cell line. Effects of insulin and growth factors.
    The Journal of biological chemistry, 1991, Aug-05, Volume: 266, Issue:22

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding Sites; Blotting, Northern; Brimonidine Tartrate; Cyclic AMP; Dioxanes; Flow Cytometry; Glycolysis; Growth Substances; Humans; Idazoxan; Insulin; Kinetics; Nucleic Acid Hybridization; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Tumor Cells, Cultured

1991
Hamster adipocyte alpha 2-adrenoceptor changes during fat mass modifications are not directly dependent on adipose tissue norepinephrine content.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cricetinae; Dioxanes; Energy Intake; Food Deprivation; Hydroxydopamines; Idazoxan; Lipolysis; Male; Mesocricetus; Norepinephrine; Oxidopamine; Pindolol; Quinoxalines; Receptors, Adrenergic, alpha; Sympathectomy, Chemical

1990
Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites.
    Molecular pharmacology, 1990, Volume: 37, Issue:6

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Binding Sites; Brimonidine Tartrate; Cell Membrane; Cystamine; Dioxanes; Dioxins; Epinephrine; Female; Humans; Idazoxan; Magnesium Chloride; Phenoxybenzamine; Potassium Chloride; Quinoxalines; Tritium; Yohimbine

1990
Discrimination between alpha 2-adrenoceptors and [3H]idazoxan-labelled non-adrenergic sites in rabbit white fat cells.
    European journal of pharmacology, 1990, Apr-25, Volume: 188, Issue:4-5

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; Dioxanes; Dioxins; Epinephrine; Idazoxan; In Vitro Techniques; Kinetics; Lipolysis; Male; Quinoxalines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Drug; Structure-Activity Relationship

1990
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1990
Photoperiodic control of adipocyte alpha 2-adrenoceptors in Syrian hamsters: role of testosterone.
    Endocrinology, 1990, Volume: 127, Issue:3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Cricetinae; Dioxanes; Idazoxan; Isoproterenol; Kidney; Light; Lipolysis; Male; Mesocricetus; Periodicity; Pindolol; Quinoxalines; Receptors, Adrenergic, alpha; Testosterone

1990
Identification of human platelet alpha 2-adrenoceptors with a new antagonist [3H]-RX821002, a 2-methoxy derivative of idazoxan.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; In Vitro Techniques; Kinetics; Male; Membranes; Oxymetazoline; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine

1990
Increased alpha 2-adrenergic binding sites and antilipolytic effect in adipocytes from genetically obese rats.
    Journal of lipid research, 1990, Volume: 31, Issue:5

    Topics: Adipose Tissue; Animals; Binding Sites; Brimonidine Tartrate; Dioxanes; Epinephrine; Idazoxan; Kinetics; Lipolysis; Male; Obesity; Propranolol; Quinoxalines; Rats; Rats, Zucker; Receptors, Adrenergic, alpha

1990
Imidazolinic radioligands for the identification of hamster adipocyte alpha 2-adrenoceptors.
    European journal of pharmacology, 1989, Nov-21, Volume: 171, Issue:2-3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cricetinae; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipolysis; Male; Mesocricetus; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine

1989
Effects of three alpha 2-adrenoceptor agonists, rilmenidine, UK 14304 and clonidine on bradykinin- and substance P-induced airway microvascular leakage in guinea-pigs.
    Neuropeptides, 1995, Volume: 28, Issue:4

    Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Capillaries; Capillary Permeability; Clonidine; Dioxanes; Extravascular Lung Water; Guinea Pigs; Idazoxan; Oxazoles; Prazosin; Quinoxalines; Rilmenidine; Substance P; Trachea

1995
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine

1995
Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Base Sequence; Brimonidine Tartrate; Bucladesine; Catecholamines; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Dioxanes; DNA Primers; Epididymis; Gene Expression; Idazoxan; Isoproterenol; Lipase; Lipolysis; Male; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; RNA, Messenger; Skin

1995
Mechanism of sympathoinhibition by imidazolines.
    Annals of the New York Academy of Sciences, 1995, Jul-12, Volume: 763

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Brimonidine Tartrate; Dioxanes; Hemodynamics; Idazoxan; Imidazoles; Oxazoles; Quinoxalines; Rabbits; Rilmenidine; Sympathetic Nervous System; Yohimbine

1995
Acute and chronic effects of reserpine on biochemical and functional parameters of central and peripheral alpha 2-adrenoceptors.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Clonidine; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Injections, Subcutaneous; Male; Mydriasis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Reserpine; Tyrosine 3-Monooxygenase; Vas Deferens

1993
Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Adrenergic alpha-Agonists; Azepines; Brimonidine Tartrate; Dioxanes; GTP Phosphohydrolases; Humans; Idazoxan; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinoxalines; Receptors, Adrenergic, alpha; Superoxides; Tritium; Tumor Cells, Cultured

1994
Estradiol reduction of the agonist high affinity form of the alpha 2-adrenoceptor in the hypothalamus of female rats: identification as the alpha 2D subtype.
    Molecular pharmacology, 1994, Volume: 45, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; Dioxanes; Estradiol; Female; Hypothalamus; Idazoxan; Kinetics; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1994
Density of alpha-2A adrenoceptors and Gi proteins in the human brain: ratio of high-affinity agonist sites to antagonist sites and effect of age.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Brain Chemistry; Brimonidine Tartrate; Child; Child, Preschool; Clonidine; Dioxanes; Female; GTP-Binding Proteins; Humans; Idazoxan; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2

1994
Alpha 2-adrenergic stimulation promotes preadipocyte proliferation. Involvement of mitogen-activated protein kinases.
    The Journal of biological chemistry, 1994, Dec-02, Volume: 269, Issue:48

    Topics: 3T3 Cells; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Clone Cells; Clonidine; Cyclic AMP; Dioxanes; Humans; Idazoxan; Kinetics; Male; Mice; Pertussis Toxin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Transfection; Virulence Factors, Bordetella

1994
Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Blood Proteins; Brimonidine Tartrate; Cell Membrane; Dioxanes; Epinephrine; Humans; Hydroxylation; Idazoxan; In Vitro Techniques; Lipolysis; Male; Platelet Aggregation; Protein Binding; Quinoxalines; Yohimbine

1993
Characterization and distribution of alpha 2-adrenergic receptors in the human intestinal mucosa.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cell Membrane; Colon; Dioxanes; Duodenum; Epinephrine; Epithelium; Humans; Idazoxan; Intestinal Mucosa; Kinetics; Microvilli; NAD; Organ Specificity; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; RNA, Messenger; Virulence Factors, Bordetella

1993
Coupling of the alpha 2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cells.
    The Biochemical journal, 1993, May-15, Volume: 292 ( Pt 1)

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Dioxanes; GTP-Binding Proteins; Humans; Idazoxan; Pertussis Toxin; Quinoxalines; Receptors, Adrenergic, alpha; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella

1993
Acute and chronic effects of cholinesterase inhibitors and pilocarpine on the density and sensitivity of central and peripheral alpha 2-adrenoceptors.
    European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Cholinesterase Inhibitors; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Isoflurophate; Male; Neostigmine; Physostigmine; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tyrosine 3-Monooxygenase; Vas Deferens

1993
Acceleration by chronic treatment with clorgyline of the turnover of brain alpha 2-adrenoceptors in normotensive but not in spontaneously hypertensive rats.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Chemistry; Brimonidine Tartrate; Cerebral Cortex; Clorgyline; Dioxanes; Down-Regulation; Hypertension; Idazoxan; In Vitro Techniques; Kinetics; Male; Membranes; Quinolines; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Species Specificity

1993
Antagonists that differentiate between alpha 2A-and alpha 2D-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Benzofurans; Brimonidine Tartrate; Cerebral Cortex; Dioxanes; Electric Stimulation; Female; Guinea Pigs; Idazoxan; Imidazoles; Isotope Labeling; Male; Norepinephrine; Oxathiins; Quinolizines; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tritium

1996
Alterations in the central nervous alpha 2-adrenoceptor system under chronic psychosocial stress.
    Neuroscience, 1996, Volume: 75, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Chronic Disease; Down-Regulation; Hydrocortisone; Idazoxan; Locus Coeruleus; Male; Nerve Tissue Proteins; Norepinephrine; Oxymetazoline; Pituitary-Adrenal System; Prefrontal Cortex; Quinoxalines; Receptors, Adrenergic, alpha-2; Social Dominance; Solitary Nucleus; Stress, Psychological; Tupaiidae; Up-Regulation; Vagus Nerve

1996
Alpha-2a/d adrenoceptor subtype stimulation by guanfacine increases osmolar clearance.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Body Water; Brimonidine Tartrate; Guanfacine; Idazoxan; Kidney; Male; Naltrexone; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1997
Influence of prolonged fasting and thyroid hormone on the alpha 2-adrenergic response in isolated epididymal adipocytes of Wistar rats.
    European journal of endocrinology, 1997, Volume: 136, Issue:2

    Topics: Adipocytes; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Separation; Epididymis; Fasting; Idazoxan; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Time Factors; Triiodothyronine

1997
Functional consequences of constitutively active alpha2A-adrenergic receptor expression in 3T3F442A preadipocytes and adipocytes.
    Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3

    Topics: 3T3 Cells; Adipocytes; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Culture Media, Serum-Free; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Idazoxan; Kinetics; Lipolysis; Mice; Mutagenesis, Site-Directed; Phosphotyrosine; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Sodium Chloride; Transfection

1997
Characterisation of pre- and post-synaptic alpha-adrenoceptors in modulation of the rat ileum longitudinal and circular muscle activities.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Clonidine; Electric Stimulation; Idazoxan; Ileum; In Vitro Techniques; Muscle Contraction; Oxymetazoline; Phentolamine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Presynaptic

1997
Alpha-adrenoceptors in equine digital veins: evidence for the presence of both alpha1 and alpha2-receptors mediating vasoconstriction.
    Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dopamine; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Veins; Yohimbine

1997
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
    Receptors & signal transduction, 1997, Volume: 7, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine

1997
Sodium saccharin inhibits adenylyl cyclase activity in non-taste cells.
    Cellular signalling, 1997, Volume: 9, Issue:6

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adrenergic alpha-Agonists; Animals; Astrocytes; Brimonidine Tartrate; Carcinogens; Cell Fractionation; Cell Membrane; Cerebral Cortex; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Idazoxan; Male; Pertussis Toxin; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Wistar; Saccharin; Signal Transduction; Swine; Taste; Thyroid Gland; Virulence Factors, Bordetella

1997
Selective increase of alpha2A-adrenoceptor agonist binding sites in brains of depressed suicide victims.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Autoradiography; Binding, Competitive; Brain Chemistry; Brimonidine Tartrate; Cell Membrane; Clonidine; Depression; Female; Frontal Lobe; Humans; Idazoxan; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2; Suicide; Tritium

1998
Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth.
    The Journal of clinical investigation, 1998, Apr-01, Volume: 101, Issue:7

    Topics: 3T3 Cells; Actin Cytoskeleton; Actins; Adipocytes; Adult; Animals; Brimonidine Tartrate; Cell Differentiation; Cell Division; Cells, Cultured; Culture Techniques; Female; Humans; Idazoxan; Lysophospholipids; Mice; Paracrine Communication; Quinoxalines; Receptors, Adrenergic, alpha-2

1998
Effects of the alkylating agent EEDQ on regulatory G proteins and recovery of agonist and antagonist alpha2-adrenoceptor binding sites in rat brain.
    European journal of pharmacology, 1998, Jun-12, Volume: 351, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Brimonidine Tartrate; Cerebral Cortex; GTP-Binding Proteins; Idazoxan; Male; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley

1998
Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; CHO Cells; Cricetinae; Guanfacine; Humans; Idazoxan; Imidazoles; Ligands; Medetomidine; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Yohimbine

1998
Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Carcinoma, Hepatocellular; Humans; Idazoxan; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-2; RNA, Messenger; Tritium; Tumor Cells, Cultured

1999
G-protein activation by putative antagonists at mutant Thr373Lys alpha2A adrenergic receptors.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; COS Cells; GTP-Binding Proteins; Humans; Idazoxan; Inositol Phosphates; Mice; Mutation; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship

1999
Determination of the somatodendritic alpha2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo.
    European journal of pharmacology, 1999, Aug-20, Volume: 379, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Brimonidine Tartrate; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Dendritic Cells; Drug Interactions; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Time Factors

1999
Autoradiographical and behavioural effects of a chronic infusion of antisense to the alpha2D-adrenoceptor in the rat.
    British journal of pharmacology, 1999, Volume: 128, Issue:3

    Topics: Animals; Autoradiography; Base Sequence; Behavior, Animal; Body Temperature; Brain; Brimonidine Tartrate; Idazoxan; Injections, Intraventricular; Male; Pupil; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; RNA, Antisense

1999
Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Cricetinae; Cysteine; Dopamine Antagonists; Humans; Idazoxan; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Protein Structure, Tertiary; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Sequence Homology, Amino Acid; Serine; Transfection; Tritium; Yohimbine

2000
Alpha(2)-adrenoceptor-stimulated GTP gamma S binding in rat brain: an autoradiographic study.
    European journal of pharmacology, 2000, Jun-30, Volume: 399, Issue:1

    Topics: Animals; Autoradiography; Brain; Brimonidine Tartrate; Dose-Response Relationship, Drug; Epinephrine; Female; Guanosine 5'-O-(3-Thiotriphosphate); Idazoxan; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin

2000
Agonist efficacy at the alpha2A-adrenoceptor:G alpha15 fusion protein: an analysis based on Ca2+ responses.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; CHO Cells; Cricetinae; Epinephrine; Fluorescent Dyes; GTP-Binding Proteins; Humans; Idazoxan; Ligands; Mice; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Transfection

2000
Transgenic mice overexpressing alpha2A-adrenoceptors in pancreatic beta-cells show altered regulation of glucose homeostasis.
    Diabetologia, 2000, Volume: 43, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Brimonidine Tartrate; Heterozygote; Homeostasis; Humans; Idazoxan; Immunohistochemistry; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Promoter Regions, Genetic; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction

2000
Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Gene Expression Regulation; GTP-Binding Proteins; Idazoxan; Male; Membranes; Norepinephrine; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; RNA, Messenger; Tritium

2001
A robust GTP-induced shift in alpha(2)-adrenoceptor agonist affinity in tissue sections from rat brain.
    Journal of neuroscience methods, 2001, Feb-15, Volume: 105, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Brimonidine Tartrate; GTP-Binding Proteins; Guanosine Triphosphate; Idazoxan; Microtomy; Nucleotides; Protein Binding; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium

2001
Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: a dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Antagonists; Animals; Azepines; Brimonidine Tartrate; Cholinesterase Inhibitors; Dialysis; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Idazoxan; Piribedil; Prefrontal Cortex; Quinolines; Quinoxalines; Rats; Rats, Wistar

2003
Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Adrenergic Agonists; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Catecholamines; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Idazoxan; Ligands; Membrane Proteins; Models, Molecular; Molecular Structure; Mutation; Protein Structure, Tertiary; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Sequence Homology, Amino Acid; Sulfur Radioisotopes; Tritium

2003
Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis.
    Clinical and experimental immunology, 2009, Volume: 156, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Colitis; Colon; Cytokines; Dextran Sulfate; Dopamine beta-Hydroxylase; Idazoxan; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Models, Animal; Quinoxalines; Tyrosine 3-Monooxygenase

2009
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain.
    Psychopharmacology, 2012, Volume: 221, Issue:1

    Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Clonidine; Desipramine; Disease Models, Animal; Idazoxan; Locus Coeruleus; Male; MAP Kinase Signaling System; Medulla Oblongata; Neuralgia; Norepinephrine; Prefrontal Cortex; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Cord

2012
The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats.
    European journal of pharmacology, 2012, Aug-05, Volume: 688, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Idazoxan; Male; Methoxamine; Movement; Neurons; Norepinephrine; Nucleus Accumbens; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2

2012
Prevention of neutrophil extravasation by α2-adrenoceptor-mediated endothelial stabilization.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Sep-15, Volume: 193, Issue:6

    Topics: Adherens Junctions; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Antigens, CD; beta Catenin; Brimonidine Tartrate; Cadherins; CD11b Antigen; Endothelium, Vascular; gamma Catenin; Humans; Idazoxan; Inflammation; Intercellular Adhesion Molecule-1; L-Selectin; Male; Mice; Neutrophils; Peritonitis; Quinoxalines; Receptors, Adrenergic, alpha-2; Thioglycolates; Transendothelial and Transepithelial Migration; Tumor Necrosis Factor-alpha; Up-Regulation; Xylazine; Zymosan

2014