Page last updated: 2024-08-17

quinoxalines and quinocetone

quinoxalines has been researched along with quinocetone in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (4.88)29.6817
2010's37 (90.24)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Chen, K; Chen, Q; Jin, X; Tang, S; Xiao, X; Zhang, T; Zou, J1
Chen, KP; Chen, Q; Jin, X; Tang, SS; Xiao, XL; Zhang, T; Zou, JJ1
Chen, DM; Dai, MH; Huang, LL; Liu, ZY; Tao, YF; Wang, YL; Yuan, ZH1
Feng, P; Li, Y; Shen, J; Wang, Z; Wu, C; Yang, C; Zhang, S1
Dai, M; Huang, L; Huang, X; Ihsan, A; Liu, Z; Peng, D; Wang, X; Wang, Y; Yuan, ZH; Zhang, W; Zhou, W1
Bao, W; Liu, L; Luo, X; Wang, D; Wu, S; Xiao, R; Yan, H; Yang, W; Yao, P; Zhong, Y1
Chen, H; Qiao, X; Song, J; Xu, Z; Zhang, Y; Zhao, D1
Cheng, L; Feng, P; Li, L; Shen, J; Wang, Z; Wu, H; Yang, C; Zhang, S1
Liu, L; Liu, Y; Luo, X; Meng, J; Wang, D; Xu, M; Yan, H; Yang, W; Yao, P; Zhong, Y1
Chen, DM; Dai, MH; Huang, LL; Ihsan, A; Liu, ZL; Peng, DP; Tao, YF; Wang, X; Wang, YL; Yuan, ZH; Zhang, W1
Bao, W; Fu, J; Hao, L; Liu, L; Nussler, AK; Wang, D; Xiao, X; Yan, H; Yang, W; Yao, P1
Gao, H; Li, L; Li, M; Li, Y; Peng, B; Zhang, J; Zhang, S; Zhou, W1
Fang, B; He, L; Liu, Y; Xu, L; Yong, Y; Zhang, Y1
Liu, ZY; Sun, ZL1
Liu, L; Liu, Y; Rong, Y; Wang, D; Xu, M; Yan, H; Yang, W; Yao, P; Yu, M1
Li, M; Liu, Z; Qiu, X; Yang, J1
Cheng, G; Huang, L; Ihsan, A; Iqbal, Z; Liu, Z; Pan, Y; Tan, Z; Tu, H; Wang, X; Wang, Y; Yuan, Z; Zhang, W; Zhang, Y1
Deng, S; Sun, Y; Tang, S; Wang, C; Xiao, X; Zhang, C; Zhang, S; Zhao, D; Zhou, Y1
Li, G; Xiao, X; Zhang, Q1
Chen, D; Huang, L; Li, J; Liu, Z; Pan, Y; Tao, Y; Wang, X; Wu, Q; Yuan, Z1
Liu, J; Liu, L; Liu, Y; Wang, D; Wang, X; Xu, M; Yan, H; Yang, X; Yao, P; Yu, M1
Beier, RC; Cao, X; Li, Y; Liu, K; Shen, J; Zhang, S1
Fei, C; Li, T; Wang, C; Wang, M; Wang, X; Xiao, S; Xue, F; Zhang, K; Zhang, L; Zheng, H; Zheng, W1
Ahmad, I; Chen, D; Huang, L; Li, J; Liu, Z; Pan, Y; Tao, Y; Wang, X; Yuan, Z1
Ai, X; Liu, Y; Wang, F; Xu, N; Yang, H; Yang, Q1
Fei, C; Li, T; Wang, C; Wang, M; Wang, X; Xiao, S; Xue, F; Zhang, K; Zhang, L; Zheng, H1
Cao, T; Hou, G; Shi, L; Xun, W; Zhao, C; Zhou, H1
Dai, C; Li, D; Tang, S; Xiao, X; Zhao, K1
Cheng, G; Ihsan, A; Li, J; Liu, Q; Liu, Z; Wan, D; Wang, X; Yuan, Z1
Gao, H; Liu, L; Liu, Y; Luo, X; Wang, D; Wu, H; Xu, M; Yan, H; Yan, P; Yang, W; Yao, P; Zhang, S1
Dai, C; Deng, S; Li, D; Tang, S; Xiao, X; Yang, X; Zhang, S; Zhao, K; Zhou, Y1
Chen, D; Cheng, G; Dai, M; Guo, P; Ihsan, A; Liu, Z; Luo, X; Wang, X; Yang, C; Yuan, Z1
Bai, Y; Chen, D; Cheng, G; Dai, M; Ihsan, A; Liu, Z; Tao, Y; Wang, X; Wang, Y; Yuan, Z; Zhu, F1
Dai, C; Li, D; Tang, S; Xiao, X; Yang, X; Zhang, S; Zhao, K; Zhou, Y1
Dai, C; Deng, S; Tang, S; Xiao, X; Yang, X; Zhang, C; Zhang, S; Zhou, Y1
Dai, C; Li, B; Li, D; Li, H; Tang, S; Xiao, X; Zhang, S; Zhou, Y1
Chen, D; Huang, L; Liu, Z; Pan, Y; Xie, S; Xu, Y; Yuan, Z; Zhu, X1
Dai, C; Deng, S; Li, D; Tang, S; Xiao, X; Yang, X; Zhang, S; Zhou, Y1
Li, B; Li, D; Tang, S; Xiao, X; Yang, X1
Cheng, L; Han, H; Luan, Y; Shen, J; Tang, S; Zhao, J1
Fan, L; Hou, L; Hu, H; Liu, F; Yin, S; Zhao, C1

Reviews

1 review(s) available for quinoxalines and quinocetone

ArticleYear
The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:8

    Topics: Animals; Carbadox; Humans; Quinoxalines

2013

Trials

1 trial(s) available for quinoxalines and quinocetone

ArticleYear
Comparative pharmacokinetics and tissue distribution of quinocetone in crucian carp (Carassius auratus), common carp (Cyprinus carpio L.), and grass carp (Ctenopharyngodon idella) following the same experimental conditions.
    Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:4

    Topics: Animals; Area Under Curve; Carps; Half-Life; Molecular Structure; Quinoxalines; Reproducibility of Results; Species Specificity; Tissue Distribution

2015

Other Studies

39 other study(ies) available for quinoxalines and quinocetone

ArticleYear
Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:2

    Topics: Animals; Carbadox; Cell Survival; Chlorocebus aethiops; Comet Assay; DNA; DNA Damage; Dose-Response Relationship, Drug; Formazans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microsomes, Liver; Mitosis; Mutagens; Quinoxalines; Tetrazolium Salts; Vero Cells

2009
Investigation of quinocetone-induced genotoxicity in HepG2 cells using the comet assay, cytokinesis-block micronucleus test and RAPD analysis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:7

    Topics: Cell Line, Tumor; Cell Nucleus Division; Cell Proliferation; Cell Survival; Comet Assay; Cytokinesis; DNA Damage; Humans; Micronucleus Tests; Mutagens; Quinoxalines; Random Amplified Polymorphic DNA Technique

2009
Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro.
    Analytical and bioanalytical chemistry, 2010, Volume: 396, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Male; Microsomes, Liver; Molecular Structure; Quinoxalines; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2010
Identification of the major metabolites of quinocetone in swine urine using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2010, Volume: 24, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Molecular Structure; Quinoxalines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Swine; Tandem Mass Spectrometry

2010
Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats.
    Regulatory toxicology and pharmacology : RTP, 2010, Volume: 58, Issue:3

    Topics: Animals; Blood Chemical Analysis; Body Weight; Diet; Dose-Response Relationship, Drug; Female; Kidney; Lethal Dose 50; Liver; Male; Mice; No-Observed-Adverse-Effect Level; Quinoxalines; Rats; Rats, Wistar; Time Factors; Toxicity Tests; Toxicity Tests, Acute

2010
Pu-erh black tea supplementation decreases quinocetone-induced ROS generation and oxidative DNA damage in Balb/c mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:2

    Topics: Animals; Dietary Supplements; DNA Damage; Female; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Oxidative Stress; Plant Extracts; Quinoxalines; Reactive Oxygen Species; Tea

2011
Molecularly imprinted solid-phase extraction combined with high-performance liquid chromatography for analysis of trace olaquindox residues in chick feeds.
    Journal of the science of food and agriculture, 2011, Volume: 91, Issue:13

    Topics: Adsorption; Animal Feed; Animals; Anti-Infective Agents; Chickens; Chromatography, High Pressure Liquid; Food Additives; Gels; Kinetics; Limit of Detection; Microscopy, Electron, Scanning; Molecular Imprinting; Phase Transition; Polymers; Quinoxalines; Reproducibility of Results; Solid Phase Microextraction; Spectroscopy, Fourier Transform Infrared

2011
Metabolism profile of quinocetone in swine by ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry.
    European journal of drug metabolism and pharmacokinetics, 2012, Volume: 37, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Gastrointestinal Tract; Kidney; Liver; Male; Muscles; Quinoxalines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Swine; Tandem Mass Spectrometry; Time Factors

2012
Pu-erh black tea extract supplementation attenuates the oxidative DNA damage and oxidative stress in Sprague-Dawley rats with renal dysfunction induced by subchronic 3-methyl-2-quinoxalin benzenevinylketo-1,4-dioxide exposure.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:2

    Topics: Animals; Camellia sinensis; DNA Damage; Kidney Diseases; Male; Oxidative Stress; Plant Extracts; Quinoxalines; Rats; Rats, Sprague-Dawley

2012
Two generation reproduction and teratogenicity studies of feeding quinocetone fed to Wistar rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:5

    Topics: Animal Feed; Animals; Body Weight; Dose-Response Relationship, Drug; Feeding Behavior; Female; Male; Quinoxalines; Rats; Rats, Wistar; Reproduction; Teratogens; Toxicity Tests

2012
Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders.
    Journal of the science of food and agriculture, 2013, Volume: 93, Issue:6

    Topics: Adult; Animals; Cattle; Cell Culture Techniques; China; Chromosomes, Human; Comet Assay; Cytotoxins; DNA Damage; Dose-Response Relationship, Drug; Female; Food Contamination; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens; Oxidative Stress; Quinoxalines; Reactive Oxygen Species; Sex Factors; Young Adult

2013
Investigation of the ultrasound effect and target analyte selectivity of dispersive liquid-liquid microextraction and its application to a quinocetone pharmacokinetic study.
    Journal of chromatography. A, 2012, Dec-14, Volume: 1268

    Topics: Animals; Chromatography, High Pressure Liquid; Liquid Phase Microextraction; Quinoxalines; Swine; Ultrasonics

2012
Simultaneous determination of quinocetone and its major metabolites in chicken tissues by high-performance liquid chromatography tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Mar-01, Volume: 919-920

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Drug Stability; Least-Squares Analysis; Limit of Detection; Meat; Quinoxalines; Reproducibility of Results; Tandem Mass Spectrometry

2013
Nrf2/ARE is the potential pathway to protect Sprague-Dawley rats against oxidative stress induced by quinocetone.
    Regulatory toxicology and pharmacology : RTP, 2013, Volume: 66, Issue:3

    Topics: Animals; Antioxidant Response Elements; Antioxidants; Biomarkers; Catalase; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2013
Hydroxylation of quinocetone and carbadox is mediated by CYP1As in the chicken (Gallus gallus).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2013, Volume: 158, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Avian Proteins; Carbadox; Chickens; Hydroxylation; Microsomes, Liver; Quinoxalines; Substrate Specificity

2013
Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Animals; Anti-Infective Agents; Bone Marrow Cells; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA Replication; Dose-Response Relationship, Drug; Humans; Lymphocytes; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Mutagens; Mutation; Quinoxalines; Random Allocation; Salmonella typhimurium

2013
TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspases; Cell Cycle; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Quinoxalines; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tumor Necrosis Factor-alpha

2013
Porous molecularly imprinted monolithic capillary column for on-line extraction coupled to high-performance liquid chromatography for trace analysis of antimicrobials in food samples.
    Talanta, 2014, Volume: 123

    Topics: Animals; Anti-Infective Agents; Chickens; Chromatography, High Pressure Liquid; Eggs; Food Analysis; Meat; Methacrylates; Microscopy, Electron, Scanning; Molecular Imprinting; Molecular Structure; Porosity; Quinoxalines; Reproducibility of Results; Silicon Dioxide; Solid Phase Extraction; Solvents; Spectrophotometry, Infrared; Sulfameter; Sulfaquinoxaline; Swine; Thermogravimetry

2014
Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 69

    Topics: Administration, Oral; Animals; Carps; Chickens; Feces; Female; Male; Quinoxalines; Rats, Wistar; Sus scrofa; Tissue Distribution; Tritium

2014
Quinocetone-induced Nrf2/HO-1 pathway suppression aggravates hepatocyte damage of Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 69

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Body Weight; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Heme Oxygenase-1; Hepatocytes; Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Quinoxalines; Rats, Sprague-Dawley; Reactive Oxygen Species

2014
Simultaneous determination of mequindox, quinocetone, and their major metabolites in chicken and pork by UPLC-MS/MS.
    Food chemistry, 2014, Oct-01, Volume: 160

    Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Food Contamination; Meat; Quinoxalines; Solid Phase Extraction; Swine; Tandem Mass Spectrometry; Veterinary Drugs

2014
Identification of oxidative stress and responsive genes of HepG2 cells exposed to quinocetone, and compared with its metabolites.
    Cell biology and toxicology, 2014, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Apoptosis; Catalase; Cell Proliferation; DNA Damage; FMN Reductase; Gene Expression; Glucose; Glutathione; Glutathione Peroxidase; Hep G2 Cells; Humans; Malondialdehyde; Mitochondria; Oxidants; Oxidative Stress; Prolyl Hydroxylases; Proto-Oncogene Proteins c-myc; Quinoxalines; Reactive Oxygen Species; Superoxide Dismutase

2014
Tissue depletion of quinocetone and its five major metabolites in pigs, broilers, and carp fed quinocetone premix.
    Journal of agricultural and food chemistry, 2014, Oct-22, Volume: 62, Issue:42

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Carps; Chickens; Drug Residues; Food Safety; Kidney; Liver; Meat; Muscles; Quinoxalines; Swine; Veterinary Drugs

2014
Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Hep G2 Cells; Humans; Micronucleus Tests; Mitochondria; Oxidation-Reduction; Quinoxalines; RNA, Messenger

2015
Effects of curcumin on growth performance, jejunal mucosal membrane integrity, morphology and immune status in weaned piglets challenged with enterotoxigenic Escherichia coli.
    International immunopharmacology, 2015, Volume: 27, Issue:1

    Topics: Animals; Curcumin; Cytokines; Dietary Supplements; Enterocolitis; Escherichia coli; Escherichia coli Infections; Growth and Development; Immunity, Innate; Immunoglobulin A; Intestinal Mucosa; Jejunum; Quinoxalines; Swine; Weaning

2015
Curcumin attenuates quinocetone-induced oxidative stress and genotoxicity in human hepatocyte L02 cells.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:4

    Topics: Antimutagenic Agents; Antioxidants; Cell Line; Cell Survival; Comet Assay; Curcumin; DNA; DNA Damage; Glutathione; Hepatocytes; Humans; Micronucleus Tests; Oxidative Stress; Quinoxalines; Reactive Oxygen Species; Superoxide Dismutase

2015
Mechanism of adrenocortical toxicity induced by quinocetone and its bidesoxy-quinocetone metabolite in porcine adrenocortical cells in vitro.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 84

    Topics: Adrenal Cortex; Animal Feed; Animals; Animals, Inbred Strains; Anti-Bacterial Agents; Apoptosis; Biotransformation; Cells, Cultured; China; Female; Food Additives; Gene Expression Regulation, Enzymologic; Kinetics; Male; Membrane Potential, Mitochondrial; Models, Biological; Necrosis; Oxidative Stress; Quinoxalines; Renin-Angiotensin System; Sus scrofa

2015
Roles of ROS mediated oxidative stress and DNA damage in 3-methyl-2-quinoxalin benzenevinylketo-1, 4-dioxide-induced immunotoxicity of Sprague-Dawley rats.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 73, Issue:2

    Topics: Animals; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Liver; Male; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spleen; T-Lymphocytes

2015
ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line.
    Toxicology mechanisms and methods, 2016, Volume: 26, Issue:1

    Topics: Apoptosis; Azepines; Cell Survival; Drug Therapy, Combination; Gene Expression Regulation; Hep G2 Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Naphthalenes; Proto-Oncogene Proteins c-akt; Quinoxalines

2016
High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.
    Toxicology, 2016, Feb-03, Volume: 341-343

    Topics: Adrenal Gland Diseases; Aldosterone; Antioxidants; Biotransformation; Cell Line; Cell Survival; Cytochrome P-450 CYP11B2; Humans; Oxidative Stress; Proanthocyanidins; Quinoxalines; RNA, Messenger; Steroid 11-beta-Hydroxylase

2016
Genomic and proteomic analysis of the inhibition of synthesis and secretion of aldosterone hormone induced by quinocetone in NCI-H295R cells.
    Toxicology, 2016, 03-28, Volume: 350-352

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation; Genomics; Humans; Mass Spectrometry; Microarray Analysis; Oxidative Stress; Proteomics; Quinoxalines; Signal Transduction; Steroid 17-alpha-Hydroxylase

2016
Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking.
    Cell biology and toxicology, 2016, Volume: 32, Issue:2

    Topics: Activating Transcription Factor 6; Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Movement; Death-Associated Protein Kinases; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; HEK293 Cells; Hep G2 Cells; Humans; Membrane Proteins; Phosphorylation; Quinoxalines; Signal Transduction; Transcriptional Activation; Vesicular Transport Proteins

2016
AKT/TSC2/p70S6K signaling pathway is involved in quinocetone-induced death-promoting autophagy in HepG2 cells.
    Toxicology mechanisms and methods, 2016, Volume: 26, Issue:4

    Topics: Anti-Bacterial Agents; Apoptosis; Autophagy; Blotting, Western; Cell Survival; Epithelial Cells; Flow Cytometry; Gene Knockdown Techniques; Hep G2 Cells; Hepatocytes; Humans; Microscopy, Electron, Transmission; Proto-Oncogene Proteins c-akt; Quinoxalines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2016
Curcumin attenuates quinocetone induced apoptosis and inflammation via the opposite modulation of Nrf2/HO-1 and NF-kB pathway in human hepatocyte L02 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 95

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Blotting, Western; Cells, Cultured; Curcumin; Heme Oxygenase-1; Hepatocytes; Humans; Inflammation; L-Lactate Dehydrogenase; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Quinoxalines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2016
Physiologically based pharmacokinetic model for quinocetone in pigs and extrapolation to mequindox.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2017, Volume: 34, Issue:2

    Topics: Animals; Drug Residues; Models, Biological; Molecular Dynamics Simulation; Monte Carlo Method; Quinoxalines; Swine

2017
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 105

    Topics: Apoptosis; beta Catenin; Cell Line, Tumor; Hep G2 Cells; Humans; Mitochondria; Quinoxalines; Reactive Oxygen Species; Signal Transduction; Voltage-Dependent Anion Channel 1; Wnt1 Protein

2017
ROS-mediated oligomerization of VDAC2 is associated with quinocetone-induced apoptotic cell death.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 47

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Caspase Inhibitors; Dimerization; Free Radical Scavengers; Green Fluorescent Proteins; Hep G2 Cells; Hepatocytes; Humans; Membrane Transport Modulators; Microscopy, Fluorescence; Mitochondria, Liver; Osmolar Concentration; Oxidants; Peptide Fragments; Protein Multimerization; Protein Transport; Quinoxalines; Reactive Oxygen Species; Recombinant Fusion Proteins; Voltage-Dependent Anion Channel 2

2018
Toxicologic effect and transcriptome analysis for short-term orally dosed enrofloxacin combined with two veterinary antimicrobials on rat liver.
    Ecotoxicology and environmental safety, 2021, Sep-01, Volume: 220

    Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Aspartate Aminotransferases; Colistin; Drug Combinations; Drug Residues; Enrofloxacin; Environmental Exposure; Gene Expression; Gene Expression Profiling; Humans; Liver; Male; Quinoxalines; Rats, Sprague-Dawley; Time Factors; Veterinary Drugs

2021
Combination of oxytetracycline and quinocetone synergistically induces hepatotoxicity via generation of reactive oxygen species and activation of mitochondrial pathway.
    Toxicology mechanisms and methods, 2022, Volume: 32, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Mice; Mice, Inbred C57BL; Oxytetracycline; Quinoxalines; Reactive Oxygen Species

2022