Page last updated: 2024-08-17

quinoxalines and quindoxin

quinoxalines has been researched along with quindoxin in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (23.33)	18.7374
1990's	2 (3.33)	18.2507
2000's	18 (30.00)	29.6817
2010's	23 (38.33)	24.3611
2020's	3 (5.00)	2.80

Authors

Authors	Studies
Frain-Bell, W; Gardiner, J	1
Knüsel, F; Rosselet, A; Suter, W	1
Hashimoto, T; Hayakawa, S; Hayatsu, H; Namba, T; Negishi, T	1
Bakri, A; Beyersbergen van Henegouwen, GM; Bojarski, J; de Vries, H; Donker, AA	1
Nishioka, H; Nunoshiba, T	1
Bradbrook, C; Charlesworth, JD; Chu, YH; Cooper, DP; Margison, GP; O'Connor, PJ; Styles, J	1
Kovacic, P; Ryan, MD; Scamehorn, RG	1
Edwards, JR; Hennessey, TD	1
Novácek, L; Seménková, L; Sevcík, B; Soska, J; Vavrínová, D	1
Banjaw, K; Dibar, D; Flachowsky, G	1
Scheutwinkel-Reich, M; vd Hude, W	1
Arao, Y; Hayatsu, H; Negishi, K; Oka, N	1
Cihák, R; Srb, V	1
Beutin, L; Kowalski, B; Preller, E	1
Novacek, L	1
de Miguel, C; García, E; González, M; López de Ceráin, A; Martínez-Crespo, FJ; Monge, A; Narro, S; Palop, JA; Sainz, Y; Senador, V	1
Bhansali, J; Chowdhury, G; Daniels, JS; Ganley, B; Gates, KS	1
Assaad, C; Diab-Assef, M; Gali-Muhtasib, HU; Haddadin, MJ; Yared, P	1
Carta, A; Paglietti, G; Rahbar Nikookar, ME; Sanna, P; Sechi, L; Zanetti, S	1
Chignell, CF; Inbaraj, JJ; Motten, AG	1
Al-Hmaira, J; Gali-Muhtasib, H; Geara, F; Haddadin, MJ; Mona, AD; Sidani, M; Zaatari, G	1
Aldana, I; Jaso, A; Monge, A; Zarranz, B	1
Diab-Assaf, M; Gali-Muhtasib, HU; Haddadin, MJ	1
Bua, A; Cannas, S; Carta, A; Deriu, A; Molicotti, P; Paglietti, G; Sechi, LA; Zanetti, S	1
Azqueta, A; Cascante, M; Creppy, EE; López de Cerain, A; Pachón, G	1
Abram, U; Araujo, J; Azqueta, A; Cerecetto, H; Costa-Filho, AJ; Gambino, D; González, M; Lavaggi, ML; López de Cerain, A; Torre, MH; Vega, AM	1
Carta, A; Corona, P; Loriga, M	1
Adachi, Y; Cerecetto, H; Costa-Filho, AJ; Gambino, D; González, M; Lavaggi, ML; Noblía, P; Sakurai, H; Torre, MH; Vieites, M	1
Aguirre, G; Arredondo, C; Basombrío, MA; Boiani, M; Cerecetto, H; Fernández, M; González, M; León, E; Pacheco, JP; Pintos, C; Raymondo, S	1
Carmeli, M; Rozen, S	1
Azqueta, A; Cia, F; de Cerain, AL; García-Jalón, JA; García-Rodríguez, A; Gil, AG; Monge, A; Zarranz, B	1
Aldana, I; Bongard, E; Burguete, A; Charnaud, S; Lima, LM; Monge, A; Perez-Silanes, S; Solano, B; Vicente, E; Villar, R; Vivas, L	1
Aldana, I; Ancizu, S; Burguete, A; Monge, A; Pérez-Silanes, S; Solano, B; Vicente, E; Villar, R	1
Aldana, I; Cho, SH; Franzblau, SG; Goldman, RC; Lenaerts, AJ; Maddry, JA; Monge, A; Pérez-Silanes, S; Solano, B; Vicente, E; Villar, R	1
Amin, KM; Ammar, YA; Ismail, MM; Noaman, E; Soliman, DH	1
Benítez, D; Castro, EA; Cerecetto, H; Duchowicz, PR; González, M; Monge, A; Vicente, E	1
El-Khatib, M; Gali-Muhtasib, H; Geara, F; Haddadin, MJ	1
Aldana, I; Burguete, A; Cabanillas, B; Castillo, D; Deharo, E; Estevez, Y; Málaga, E; Monge, A; Pérez-Silanes, S; Quiliano, M; Verástegui, M; Zimic, M	1
Goldman, RC	1
Aldana, I; Goldman, RC; Mong, A; Pérez-Silanes, S; Vicente, E; Villar, R	1
Fettinger, JC; Ghattass, KI; Haddadin, MJ; Kurth, MJ; Shoker, TA	1
Fang, B; He, L; He, Q; Su, Y; Yang, J; Zeng, D; Zeng, Z	1
Fernandes, R; Noronha, JP; Pinheiro, C; Prudêncio, C; Vieira, M	1
Chen, Q; Deng, Y; Mu, P; Tang, X; Wang, L; Wang, Y; Wu, K; Xu, M; Zheng, M; Zheng, Y	1
El-Sabban, M; El-Sitt, S; Gali-Muhtasib, H; Ghattass, K; Haddadin, MJ; Rayes, S; Zibara, K	1
Anderson, RF; Denny, WA; Hay, MP; Marshall, AJ; Reynisson, J; Yadav, P	1
Le, T; Shu, L; Zhang, L; Zhu, L	1
Arbillaga, L; Azqueta, A; Cerecetto, H; González, M; Moreno-Viguri, E; Pérez-Silanes, S; Torres, E; Varela, J	1
Chen, D; Cheng, G; Dai, M; Guo, P; Ihsan, A; Liu, Z; Luo, X; Wang, X; Yang, C; Yuan, Z	1
Moreno-Viguri, E; Pérez-Silanes, S; Santivañez-Veliz, M; Torres, E	1
Aldana, I; Barea, C; Deharo, E; Galiano, S; Pabón, A; Quiliano, M; Ramirez-Calderon, G	1
Andrade-Ochoa, S; Chacón-Vargas, KF; Juárez-Ramírez, DC; Lara-Ramírez, EE; Mondragón-Flores, R; Monge, A; Nogueda-Torres, B; Rivera, G; Sánchez-Torres, LE	1
Aldana, I; Beltrán-Hortelano, I; Bonilla-Ramirez, L; Bordessoulles, M; Corcuera, L; Franetich, JF; Galiano, S; López de Cerain, A; Mazier, D; Pabón, A; Quiliano, M; Ramirez-Calderon, G; Rios, A; Vettorazzi, A	1
Coelho, P; Prudêncio, C; Silva, L; Soares, R; Vieira, M	1
Li, J; Li, Y; Mao, X; Sumarah, MW; Sun, M; Wang, Y; You, Y	1
Aldana, I; Bonilla-Ramírez, L; Galiano, S; Pabón, A; Quiliano, M	1
Cabrera, M; Cerecetto, H; Corvo, I; Ferraro, F; Gil, J; Merlino, A	1
Coelho, P; Monteiro, A; Pinto, G; Prudêncio, C; Silva, L; Soares, R; Teixeira, D; Vieira, M	1
Rivera, G	1
Agrawal, N; Bhardwaj, A	1

Reviews

5 review(s) available for quinoxalines and quindoxin

Article	Year
Methylated purines formed in DNA by dimethylnitrosamine in rats previously exposed to hepatotoxic and hepatocarcinogenic regimes: effects on the repair of O6-methylguanine. Chemico-biological interactions, 1985, Volume: 53, Issue:3 Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Animals; Dimethylnitrosamine; DNA; DNA Repair; Ethanolamines; Guanine; Liver; Male; Quinoxalines; Rats; Rats, Inbred Strains	1985
Quinoxaline 1,4-dioxide: a versatile scaffold endowed with manifold activities. Current medicinal chemistry, 2005, Volume: 12, Issue:19 Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Screening Assays, Antitumor; Humans; Mutagenicity Tests; Photochemistry; Quinoxalines; Structure-Activity Relationship; Tumor Cells, Cultured	2005
Quinoxaline 1,4-di-N-oxide and the potential for treating tuberculosis. Infectious disorders drug targets, 2011, Volume: 11, Issue:2 Topics: Animals; Antitubercular Agents; Drug Resistance, Bacterial; Humans; Mice; Quinoxalines; Structure-Activity Relationship	2011
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors? Mini reviews in medicinal chemistry, 2022, Volume: 22, Issue:1 Topics: Mycobacterium tuberculosis; Oxides; Quinoxalines; Structure-Activity Relationship	2022
An appraisal on synthetic and pharmaceutical perspectives of quinoxaline 1,4-di-N-oxide scaffold. Chemical biology & drug design, 2022, Volume: 100, Issue:3 Topics: Anti-Bacterial Agents; Oxides; Pharmaceutical Preparations; Quinoxalines	2022

Other Studies

55 other study(ies) available for quinoxalines and quindoxin

Article	Year
Photocontact dermatitis due to quindoxin. Contact dermatitis, 1975, Volume: 1, Issue:4 Topics: Aged; Animal Feed; Dermatitis, Contact; Dermatitis, Occupational; Food Additives; Humans; Male; Middle Aged; Photosensitivity Disorders; Quinoxalines	1975
Mode of action of quindoxin and substituted quinoxaline-di-N-oxides on Escherichia coli. Antimicrobial agents and chemotherapy, 1978, Volume: 13, Issue:5 Topics: Anaerobiosis; Anti-Bacterial Agents; Chloramphenicol; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Macromolecular Substances; Mutation; Oxidation-Reduction; Quinoxalines	1978
Mutagenicity of quinoline derivatives and analogs-quinoxaline 1,4-dioxide is a potent mutagen. Chemical & pharmaceutical bulletin, 1979, Volume: 27, Issue:8 Topics: Mutagens; Quinolines; Quinoxalines	1979
Photochemical reactions of quindoxin, olaquindox, carbadox and cyadox with protein, indicating photoallergic properties. Toxicology, 1990, Volume: 63, Issue:1 Topics: Animals; Anti-Bacterial Agents; Carbadox; Chemical Phenomena; Chemistry; Humans; Organophosphorus Compounds; Photochemistry; Photosensitivity Disorders; Proteins; Quinoxalines; Serum Albumin; Ultraviolet Rays	1990
Genotoxicity of quinoxaline 1,4-dioxide derivatives in Escherichia coli and Salmonella typhimurium. Mutation research, 1989, Volume: 217, Issue:3 Topics: Dose-Response Relationship, Drug; Escherichia coli; Mutagenicity Tests; Mutation; Quinoxalines; Salmonella typhimurium; SOS Response, Genetics; Structure-Activity Relationship	1989
Charge transfer in the mechanism of drug action involving quinoxaline di-N-oxides. Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Electron Transport; Mutagens; Quinoxalines	1985
Antibacterial properties of quindoxin: a new growth-promoting agent. The Veterinary record, 1972, Feb-12, Volume: 90, Issue:7 Topics: Anaerobiosis; Animals; Bacitracin; Chickens; Clostridium; Cyclic N-Oxides; Escherichia coli; Feces; Growth; Oxytetracycline; Penicillin G; Penicillin Resistance; Quinoxalines; Staphylococcus; Virginiamycin	1972
[Study of the biological effects of quinoxaline-1,4-dioxide]. Ceskoslovenska farmacie, 1984, Volume: 33, Issue:5 Topics: Animals; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Chickens; Escherichia coli; Growth; Mutagens; Quinoxalines; Staphylococcus aureus	1984
Feed additives to chick starter mixtures under tropical conditions. Beitrage zur tropischen Landwirtschaft und Veterinarmedizin, 1984, Volume: 22, Issue:3 Topics: Animals; Anti-Bacterial Agents; Body Weight; Chickens; Eating; Energy Metabolism; Ethiopia; Female; Food Additives; Male; Nitrofurans; Nitrovin; Quinoxalines; Tropical Climate	1984
Sister-chromatid exchange in Chinese hamster V79 cells exposed to quindoxin, carbadox and olaquindox. Mutation research, 1984, Volume: 139, Issue:4 Topics: Animals; Carbadox; Cells, Cultured; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Quinoxalines; Sister Chromatid Exchange; Structure-Activity Relationship	1984
DNA damage induced with near-ultraviolet light irradiation in the presence of quinoxaline-1,4-dioxide. Nucleic acids symposium series, 1980, Issue:8 Topics: Bacillus subtilis; DNA, Bacterial; Mutagens; Quinoxalines; Ultraviolet Rays	1980
Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. I. Micronucleus test in rats. Mutation research, 1983, Volume: 116, Issue:2 Topics: Animals; Anti-Bacterial Agents; Bone Marrow; Carbadox; Cell Nucleus; Erythrocytes; Male; Mutagenicity Tests; Mutagens; Mutation; Quinoxalines; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1983
Mutagenicity of quindoxin, its metabolites, and two substituted quinoxaline-di-N-oxides. Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:3 Topics: Anaerobiosis; Carbadox; Cyclic N-Oxides; DNA Repair; Mutagens; Quinoxalines; Salmonella typhimurium	1981
[The antibacterial, quinoxaline 1,4-dioxide]. Ceskoslovenska farmacie, 1981, Volume: 30, Issue:1 Topics: Animals; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Mice; Quinoxalines	1981
Hypoxia-selective agents derived from quinoxaline 1,4-di-N-oxides. Journal of medicinal chemistry, 1995, May-12, Volume: 38, Issue:10 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Mice; Mice, Inbred BALB C; Quinoxalines; Tirapazamine; Triazines; Tumor Cells, Cultured	1995
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:9 Topics: Antibiotics, Antineoplastic; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Hypoxia; Oxidation-Reduction; Plasmids; Quinoxalines; Xanthine; Xanthine Oxidase	2001
Quinoxaline 1,4-dioxides: hypoxia-selective therapeutic agents. Molecular carcinogenesis, 2002, Volume: 33, Issue:4 Topics: Aerobiosis; Antineoplastic Agents; Cell Hypoxia; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Kinetics; Quinoxalines; Structure-Activity Relationship; Tumor Cells, Cultured	2002
Novel substituted quinoxaline 1,4-dioxides with in vitro antimycobacterial and anticandida activity. European journal of medicinal chemistry, 2002, Volume: 37, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candida; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinoxalines	2002
Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues. Chemical research in toxicology, 2003, Volume: 16, Issue:2 Topics: Antineoplastic Agents; Azides; Computer Simulation; Cyclic N-Oxides; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; NAD; Oxidation-Reduction; Photolysis; Plasmids; Quinoxalines; Radiation-Sensitizing Agents; Singlet Oxygen; Spectrophotometry; Spin Labels; Tirapazamine; Triazines	2003
Quinoxaline 1,4-dioxides are novel angiogenesis inhibitors that potentiate antitumor effects of ionizing radiation. International journal of oncology, 2004, Volume: 24, Issue:5 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Lewis Lung; Cell Hypoxia; Cell Survival; Collagen; Combined Modality Therapy; Drug Combinations; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Necrosis; Neovascularization, Pathologic; Proteoglycans; Quinoxalines; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vascular Endothelial Growth Factor A	2004
Synthesis and anticancer activity evaluation of new 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethyl-quinoxaline 1,4-di-N-oxide derivatives. Bioorganic & medicinal chemistry, 2004, Jul-01, Volume: 12, Issue:13 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Quinoxalines	2004
Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells. Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:4 Topics: Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Division; Cells, Cultured; Colonic Neoplasms; Cyclin B; Extracellular Signal-Regulated MAP Kinases; Humans; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
In vitro activity of new quinoxalin 1,4-dioxide derivatives against strains of Mycobacterium tuberculosis and other mycobacteria. International journal of antimicrobial agents, 2005, Volume: 25, Issue:2 Topics: Animals; Antitubercular Agents; Cattle; Cell Line; Drug Resistance, Bacterial; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium Infections; Mycobacterium tuberculosis; Quinoxalines; Tuberculosis, Pulmonary	2005
DNA damage induced by a quinoxaline 1,4-di-N-oxide derivative (hypoxic selective agent) in Caco-2 cells evaluated by the comet assay. Mutagenesis, 2005, Volume: 20, Issue:3 Topics: Apoptosis; Caco-2 Cells; Cell Hypoxia; Cell Nucleus; Cell Proliferation; Cell Survival; Comet Assay; DNA; DNA Damage; DNA Repair; Humans; Mutagens; Oxidation-Reduction; Quinoxalines	2005
Novel Cu(II) quinoxaline N1,N4-dioxide complexes as selective hypoxic cytotoxins. European journal of medicinal chemistry, 2005, Volume: 40, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Copper; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fibroblasts; Models, Molecular; Organometallic Compounds; Quinoxalines; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Surface Properties	2005
Novel vanadyl complexes with quinoxaline N(1),N(4)-dioxide derivatives as potent in vitro insulin-mimetic compounds. Journal of inorganic biochemistry, 2006, Volume: 100, Issue:2 Topics: Adipocytes; Animals; Cells, Cultured; Electron Spin Resonance Spectroscopy; Ephedrine; Hypoglycemic Agents; Insulin; Lipolysis; Male; Molecular Mimicry; Molecular Structure; Organometallic Compounds; Quinoxalines; Rats; Rats, Wistar; Vanadates	2006
Furoxan derivatives as cytotoxic agents: preliminary in vivo antitumoral activity studies. Die Pharmazie, 2006, Volume: 61, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oxadiazoles; Quinoxalines; Sarcoma, Experimental	2006
A new efficient route for the formation of quinoxaline N-oxides and N,N'-dioxides using HOF.CH3CN. The Journal of organic chemistry, 2006, Jul-21, Volume: 71, Issue:15 Topics: Acetonitriles; Fluorine; Hydrogen; Molecular Structure; Oxidation-Reduction; Oxides; Quinoxalines	2006
Comparative acute systemic toxicity of several quinoxaline 1,4-di-N-oxides in Wistar rats. Arzneimittel-Forschung, 2007, Volume: 57, Issue:6 Topics: Animals; Body Weight; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Quinoxalines; Rats; Rats, Wistar; Solubility; Structure-Activity Relationship	2007
Synthesis and structure-activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents. European journal of medicinal chemistry, 2008, Volume: 43, Issue:9 Topics: Animals; Antimalarials; Cattle; Cell Survival; Drug Design; Humans; KB Cells; Plasmodium falciparum; Quinoxalines; Structure-Activity Relationship	2008
Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives. Molecules (Basel, Switzerland), 2008, Jan-18, Volume: 13, Issue:1 Topics: Antitubercular Agents; Fluorine; Mass Spectrometry; Phenols; Quinoxalines	2008
In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide. The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:3 Topics: Administration, Oral; Animals; Antitubercular Agents; Biotransformation; Drug Resistance, Multiple, Bacterial; Female; Mice; Microbial Sensitivity Tests; Microbial Viability; Molecular Structure; Mycobacterium tuberculosis; Quinoxalines; Tuberculosis; Tuberculosis, Multidrug-Resistant	2008
New quinoxaline 1, 4-di-N-oxides: anticancer and hypoxia-selective therapeutic agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:7 Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Electrons; Humans; Inhibitory Concentration 50; Quinoxalines	2010
Anti-T. cruzi activities and QSAR studies of 3-arylquinoxaline-2-carbonitrile di-N-oxides. Bioorganic & medicinal chemistry letters, 2010, Aug-15, Volume: 20, Issue:16 Topics: Nifurtimox; Oxides; Quantitative Structure-Activity Relationship; Quinoxalines; Trypanocidal Agents; Trypanosoma cruzi	2010
Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21. Radiation oncology (London, England), 2010, Nov-15, Volume: 5 Topics: Antineoplastic Agents; Carcinoma; Cell Death; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Drug Evaluation, Preclinical; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Quinoxalines; Tumor Suppressor Protein p53	2010
Trypanocidal properties, structure-activity relationship and computational studies of quinoxaline 1,4-di-N-oxide derivatives. Experimental parasitology, 2011, Volume: 127, Issue:4 Topics: Animals; Chlorocebus aethiops; Female; Leishmania; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molecular Structure; Quinoxalines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells	2011
Maximizing bactericidal activity with combinations of bioreduced drugs. Future medicinal chemistry, 2010, Volume: 2, Issue:8 Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Drug Combinations; Drug Discovery; Free Radicals; Humans; Mycobacterium tuberculosis; Nitrofurans; Nitroimidazoles; Oxidation-Reduction; Quinoxalines; Tuberculosis	2010
Unusual Friedlander reactions: a route to novel quinoxaline-based heterocycles. Organic letters, 2012, Jul-20, Volume: 14, Issue:14 Topics: Crystallography, X-Ray; Cyclopentanes; Molecular Structure; Quinoxalines	2012
Simultaneous determination of quinoxaline-1,4-dioxides in feeds using molecularly imprinted solid-phase extraction coupled with HPLC. Journal of separation science, 2013, Volume: 36, Issue:2 Topics: Adsorption; Animal Feed; Anti-Bacterial Agents; Food Contamination; Molecular Imprinting; Polymers; Quinoxalines; Solid Phase Extraction	2013
Antimicrobial activity of quinoxaline 1,4-dioxide with 2- and 3-substituted derivatives. Microbiological research, 2014, Volume: 169, Issue:4 Topics: Anti-Infective Agents; Candida albicans; Escherichia coli; Microbial Sensitivity Tests; Microbial Viability; Quinoxalines; Saccharomyces cerevisiae; Staphylococcus aureus	2014
N-oxide reduction of quinoxaline-1,4-dioxides catalyzed by porcine aldehyde oxidase SsAOX1. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:4 Topics: Aldehyde Oxidase; Amino Acid Sequence; Amino Acid Substitution; Animals; Catalysis; Circular Dichroism; Cloning, Molecular; Female; Glycine; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Quinoxalines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sus scrofa; Threonine	2014
The quinoxaline di-N-oxide DCQ blocks breast cancer metastasis in vitro and in vivo by targeting the hypoxia inducible factor-1 pathway. Molecular cancer, 2014, Jan-24, Volume: 13 Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Quinoxalines; RNA, Small Interfering; Signal Transduction; Transfection; Xenograft Model Antitumor Assays	2014
Fragmentation of the quinoxaline N-oxide bond to the ˙OH radical upon one-electron bioreduction. Chemical communications (Cambridge, England), 2014, Nov-18, Volume: 50, Issue:89 Topics: Antineoplastic Agents; Humans; Hydroxyl Radical; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxides; Pyrroles; Quinoxalines; Tirapazamine; Triazines	2014
Simultaneous determination of five quinoxaline-1,4-dioxides in animal feeds using an immunochromatographic strip. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2016, Volume: 33, Issue:2 Topics: Animal Feed; Animals; Antibodies; Antigen-Antibody Reactions; Chromatography, Affinity; Chromatography, High Pressure Liquid; Gold; Metal Nanoparticles; Quinoxalines	2016
Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity. Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3 Topics: Animals; Cell Survival; Chlorocebus aethiops; Nitrogen; Oxides; Quinoxalines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells	2016
High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells. Toxicology, 2016, Feb-03, Volume: 341-343 Topics: Adrenal Gland Diseases; Aldosterone; Antioxidants; Biotransformation; Cell Line; Cell Survival; Cytochrome P-450 CYP11B2; Humans; Oxidative Stress; Proanthocyanidins; Quinoxalines; RNA, Messenger; Steroid 11-beta-Hydroxylase	2016
Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis. Bioorganic & medicinal chemistry letters, 2016, May-01, Volume: 26, Issue:9 Topics: Animals; Antitubercular Agents; Cell Line; Cyclic N-Oxides; Drug Resistance, Multiple, Bacterial; Latent Tuberculosis; Mice; Mycobacterium tuberculosis; Quinoxalines; Tuberculosis, Multidrug-Resistant	2016
New hydrazine and hydrazide quinoxaline 1,4-di-N-oxide derivatives: In silico ADMET, antiplasmodial and antileishmanial activity. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Antiprotozoal Agents; Humans; Hydrazines; Leishmania infantum; Leishmaniasis, Visceral; Malaria, Falciparum; Plasmodium falciparum; Quinoxalines; Structure-Activity Relationship	2017
Isopropyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives induce regulated necrosis-like cell death on Leishmania (Leishmania) mexicana. Parasitology research, 2018, Volume: 117, Issue:1 Topics: Animals; Antiprotozoal Agents; Cell Death; Cell Line; Leishmania mexicana; Membrane Potential, Mitochondrial; Mice; Quinoxalines; Reactive Oxygen Species	2018
Novel antimalarial chloroquine- and primaquine-quinoxaline 1,4-di-N-oxide hybrids: Design, synthesis, Plasmodium life cycle stage profile, and preliminary toxicity studies. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Animals; Antimalarials; Chloroquine; Female; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Mice, Inbred BALB C; Plasmodium; Primaquine; Quinoxalines	2018
Quinoxaline-1,4-dioxide derivatives inhibitory action in melanoma and brain tumor cells. Future medicinal chemistry, 2019, Volume: 11, Issue:7 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Melanoma; Mice; Molecular Structure; Quinoxalines; Structure-Activity Relationship	2019
Tracing major metabolites of quinoxaline-1,4-dioxides in abalone with high-performance liquid chromatography tandem positive-mode electrospray ionization mass spectrometry. Journal of the science of food and agriculture, 2019, Volume: 99, Issue:12 Topics: Animals; Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Food Contamination; Gastropoda; Quinoxalines; Seafood; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2019
Primaquine-quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species. Malaria journal, 2019, Jun-19, Volume: 18, Issue:1 Topics: Antimalarials; Drug Combinations; Erythrocytes; Hep G2 Cells; Humans; Plasmodium yoelii; Primaquine; Quinoxalines; Sporozoites	2019
Cathepsin L Inhibitors with Activity against the Liver Fluke Identified From a Focus Library of Quinoxaline 1,4-di- Molecules (Basel, Switzerland), 2019, Jun-26, Volume: 24, Issue:13 Topics: Animals; Binding Sites; Cathepsin L; Cattle; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fasciola hepatica; Humans; Inhibitory Concentration 50; Male; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Quinoxalines; Spermatozoa; Structure-Activity Relationship	2019
Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives. Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Mice; Oxidative Stress; Quinoxalines; Radiation-Sensitizing Agents; Tumor Cells, Cultured	2020