quinoxalines has been researched along with prazosin in 129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (26.36) | 18.7374 |
| 1990's | 65 (50.39) | 18.2507 |
| 2000's | 21 (16.28) | 29.6817 |
| 2010's | 8 (6.20) | 24.3611 |
| 2020's | 1 (0.78) | 2.80 |
| Authors | Studies |
|---|---|
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Pinnock, RD | 1 |
| Berridge, TL; Doxey, JC; Roach, AG; Smith, CF | 1 |
| Jansen van't Land, C; van der Laan, JW | 1 |
| Lefebvre, RA; Smits, GJ | 1 |
| Deschênes, M; Pinault, D | 1 |
| Bourreau, JP; Daniel, EE; Kwan, CY; Shimamoto, H | 1 |
| Minneman, KP; Wilson, KM | 1 |
| Dunn, WR; McGrath, JC; Wilson, VG | 2 |
| Bültmann, R; Starke, K; von Kügelgen, I | 1 |
| Lepor, H | 1 |
| Flavahan, NA; Komori, K; Miller, VM; Vanhoutte, PM | 1 |
| Berlan, M; Galitzky, J; Lafontan, M; Montastruc, JL; Senard, JM; Stillings, M | 1 |
| Alari, L; Axelsson, KL; Persson, ML; Post, C; Uhlén, S; Wikberg, JE | 1 |
| Guimaraes, S; Nunes, JP | 1 |
| Altemeyer, KH; Dirks, B; Ensinger, H; Grünert, A | 1 |
| Rand, MJ; Xiao, XH | 1 |
| Doxey, JC; John, GW; Reid, JL; Walter, DS | 1 |
| Guimarães, S; Moura, D; Vaz-da-Silva, MJ | 1 |
| Brandon, S; Cragoe, EJ; Guyer, CA; Horstman, DA; Limbird, LE; Wilson, AL | 1 |
| Calvete, J; Hayes, R; Sever, PS; Thom, S | 1 |
| Lacroix, JS; Lundberg, JM | 1 |
| Hughes, AD; Martin, GN; Mulvany, MJ; Nielsen, H; Sever, PS; Thom, SM | 1 |
| Bylund, DB; Ray-Prenger, C | 1 |
| Albuquerque, AA; Goncalves, J; Paiva, MQ; Proenca, J | 1 |
| Cattaneo, AG; Doxey, JC; Efendic, S; Ostenson, CG | 1 |
| Hashimoto, K; Tsujimoto, G | 1 |
| Edwards, RM; Trizna, W | 1 |
| Harker, CT; Vanhoutte, PM | 1 |
| Downing, OA; Stein, W; Wilson, KA; Wilson, VG | 1 |
| Calvete, J; Hayes, R; Martin, G; Sever, P; Thom, S | 1 |
| Guimarães, S; Paiva, MQ; Polónia, JJ | 1 |
| Hesse, IF; Johns, EJ | 1 |
| Hyman, AL; Kadowitz, PJ | 2 |
| Dickinson, KE; McKernan, RM; Miles, CM; Sever, PS | 1 |
| Bassenge, E; Elsner, D; Holtz, J; Sommer, O; Stewart, DJ | 1 |
| Dettmar, PW; Lord, JA | 1 |
| Itoh, H; Kohli, JD; Rajfer, SI | 1 |
| Broadley, KJ; Williamson, KL | 1 |
| Guimarães, S; Moura, D; Paiva, MQ | 1 |
| Graham, RM; Powell, WJ; Supple, EW | 1 |
| Nyman, L; Saano, V; Savola, JM; Virtanen, R | 1 |
| Uhlén, S; Wikberg, JE | 1 |
| Gonçalves, J; Guimarães, S; Nunes, JP; Paiva, MQ | 1 |
| Daly, CJ; McGrath, JC; Wilson, VG | 1 |
| Messick, K; Ruffolo, RR | 1 |
| Hyman, AL; Kadowitz, PJ; Lippton, HL | 1 |
| Pipili, E | 1 |
| Flavahan, NA; Gisclard, V; Vanhoutte, PM | 1 |
| Beckeringh, JJ; De Jonge, A; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B | 1 |
| Hicks, PE | 1 |
| McWilliam, JR; Meldrum, BS | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Advenier, C; Biyah, K | 1 |
| Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG | 1 |
| Dyamenahalli, U; Haworth, SG; Stuart-Smith, K; Tulloh, RM | 1 |
| Ge, YZ; Morrison, SF | 1 |
| Cable, HC; el-Mansoury, A; Morgan, NG | 1 |
| Gazzola, C; Hunter, RA; Lisle, AT; Magner, T | 1 |
| Qü, M; Schleicher, A; Zilles, K | 1 |
| Driessen, B; Starke, K; von Kügelgen, I | 1 |
| Robinson, NE; Wang, Z; Yu, M | 1 |
| Kachroo, A; Malhotra, V; Sapru, HN | 1 |
| Faber, JE; Ikeoka, K | 1 |
| Crepel, F; Hirsch, JC; Law-Tho, D | 1 |
| Vanhoutte, PM; Wood, MB; Ye, Z | 1 |
| Giardinà, D; Gulini, U; Massi, M; Melchiorre, C; Piloni, MG; Pompei, P; Rafaiani, G | 1 |
| Angel, I; Grosset, A; Langer, SZ; Perrault, G; Schoemaker, H | 1 |
| Cheetham, SC; Heal, DJ | 1 |
| Bohmann, C; Riera-Knorrenschild, G; Rump, LC; Schollmeyer, P; Schwertfeger, E; Spillner, G | 1 |
| Crucianelli, M; Giardinà, D; Melchiorre, C; Taddei, C; Testa, R | 1 |
| Brown, DR; Malone, ED; Trent, AM; Turner, TA | 1 |
| Bryant, CE; Clarke, KW | 1 |
| Bohmann, C; Rist, W; Rump, LC; Schollmeyer, P | 1 |
| Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
| Intengan, HD; Smyth, DD | 2 |
| Oriowo, MA; Williams, KI; Yousif, M | 1 |
| Feltz, P; Hayar, A; Piguet, P | 1 |
| Nörenberg, W; Schöffel, E; Starke, K; Szabo, B | 1 |
| Elliott, J | 1 |
| Guimarães, S; Paiva, MQ; Pereira, O | 1 |
| Bayliss, DA; Guyenet, PG; Li, YW | 1 |
| Akaike, N; Arima, J; Ishibashi, H; Kubo, C | 1 |
| Gallant, CM; Goldstein, I; Gupta, S; Moreland, RB; Traish, A; Yang, S | 1 |
| Kwan, CY; Mo, FM | 1 |
| Abysique, A; Bouvier, M; Orsoni, P | 1 |
| Bredt, DS; Morton, DB | 1 |
| Hipólide, DC; Nobrega, JN; Raymond, R; Tufik, S | 1 |
| Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Daniel, EE; Kwan, CY; Loke, JC; Low, AM; Lu-Chao, H | 1 |
| Borges, AC; Feres, T; Paiva, AC; Paiva, TB; Silva, EG | 1 |
| Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T | 1 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Daly, CJ; Mackenzie, JF; McGrath, JC; Naghadeh, MA; Pediani, JD | 1 |
| Nott, MW; Rand, MJ; Thaina, P | 1 |
| Fujiki, H; Imaizumi, T; Kambayashi, J; Kimura, Y; Kishi, M; Mori, T; Orito, K; Shimizu, H; Tanaka, M; Teramoto, S; Tominaga, M; Yoshida, K | 1 |
| Eglen, RM; MacLennan, SJ; Martin, GR; Martin, RS; Reynen, PH | 1 |
| Eglen, RM; MacLennan, SJ; Martin, GR; Reynen, PH | 1 |
| Iida, S; Ishihama, K; Kogo, M; Koizumi, H; Matsuya, T; Mori, A; Tanaka, S | 1 |
| Hillier, C; Jarajapu, YP; MacDonald, A | 1 |
| Angeli, P; Giardinà, D; Gulini, U; Leonardi, A; Marucci, G; Melchiorre, C; Poggesi, E; Polimanti, O; Sagratini, G | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Bortolozzi, A; Díaz-Mataix, L; Pons, S; Serrats, J | 1 |
| Duman, RS; Russell, DS; Tolbert, LM | 1 |
| Dang, VC; Williams, JT | 1 |
| Brockhaus, J; Deitmer, JW; Hecker, C; Herold, S | 1 |
| Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
| Ananthalakshmi, KV; Edafiogho, IO; Kombian, SB | 1 |
| Kolaj, M; Renaud, LP | 1 |
| Angeli, P; Buccioni, M; Giardinà, D; Gulini, U; Leonardi, A; Marucci, G; Melchiorre, C; Poggesi, E; Sagratini, G | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Koob, GF; Lekic, DM; Mandyam, CD; Wee, S | 1 |
| Bexis, S; Docherty, JR | 1 |
| Didier, A; Jourdan, F; Marien, M; Nguyen, V; Veyrac, A | 1 |
| Bustamante, S; García-Sacristán, A; Hernández, M; Martínez, MP; Navarro-Dorado, J; Orensanz, LM; Prieto, D; Recio, P | 1 |
| Enokizono, J; Kusuhara, H; Ose, A; Schinkel, AH; Sugiyama, Y | 1 |
| Imanishi, A; Latifpour, J; Ueda, S; Yamamoto, Y; Yono, M; Yoshida, M | 1 |
| Cheevers, CV; Donello, JE; Gil, DW; Kedzie, KM; Manlapaz, CA; Rao, S; Tang, E | 1 |
| Jackson, WF; Moore, AW; Segal, SS | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Centurión, D; Hofmann, RA; Jantschak, F; Pertz, HH; Popp, AM; Villalón, CM | 1 |
| Aston-Jones, G; Smith, RJ | 1 |
| Aono, Y; Cools, AR; Koshikawa, N; Saigusa, T; Takada, K; Uchida, T; Verheij, MM | 1 |
| Bult, H; De Meyer, GR; Fransen, P; Martinet, W; Schrijvers, DM; Van Hove, CE; van Langen, JT | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
| Abdelkarim, H; Albee, LJ; Gao, X; Gaponenko, V; Majetschak, M; Volkman, BF | 1 |
| Alsufyani, HA; Docherty, JR; McCormick, PA | 1 |
1 review(s) available for quinoxalines and prazosin
| Article | Year |
|---|---|
Role of alpha-adrenergic blockers in the treatment of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Carbachol; Humans; Male; Muscle Contraction; Phenylephrine; Prazosin; Prostatic Hyperplasia; Quinoxalines | 1990 |
1 trial(s) available for quinoxalines and prazosin
| Article | Year |
|---|---|
Human vascular smooth muscle responses mediated by alpha 2 mechanisms in vivo and in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Arteries; Brimonidine Tartrate; Dioxanes; Doxazosin; Forearm; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha | 1985 |
127 other study(ies) available for quinoxalines and prazosin
| Article | Year |
|---|---|
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Blood Glucose; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Idazoxan; Imidazoles; Insulin; Male; Muscles; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1992 |
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Doxazosin; Drug Implants; Eating; Food; Male; Morphine; Morphine Dependence; Motor Activity; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Modulation of non-adrenergic non-cholinergic inhibitory neurotransmission in rat gastric fundus by the alpha 2-adrenoceptor agonist, UK-14,304.
Topics: Adrenergic alpha-Agonists; Animals; Autonomic Nervous System; Brimonidine Tartrate; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Prazosin; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide; Yohimbine | 1992 |
Control of 40-Hz firing of reticular thalamic cells by neurotransmitters.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Electric Conductivity; Female; gamma-Aminobutyric Acid; Ketanserin; Kynurenic Acid; Male; Neurons; Neurotransmitter Agents; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reticular Formation; Scopolamine; Thalamic Nuclei | 1992 |
Amplification of alpha adrenergic vasoconstriction in canine isolated mesenteric artery and vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Potassium Chloride; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction | 1992 |
Synergistic interactions between alpha 1- and alpha 2-adrenergic receptors in activating 3H-inositol phosphate formation in primary glial cell cultures.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Cells, Cultured; Dose-Response Relationship, Drug; Inositol Phosphates; Neuroglia; Norepinephrine; Osmolar Concentration; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Time Factors; Tritium; Yohimbine | 1991 |
Postjunctional alpha-adrenoceptors in the rabbit isolated distal saphenous artery: indirect sensitivity to prazosin of responses to noradrenaline mediated via postjunctional alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine | 1991 |
Electrophysiological analysis of adrenergic neurotransmission and its modulation by chronic denervation in canine saphenous veins.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Dogs; Electric Stimulation; Electrophysiology; Female; Membrane Potentials; Muscle Denervation; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Prazosin; Quinoxalines; Saphenous Vein; Synaptic Transmission | 1990 |
Identification of human platelet alpha 2-adrenoceptors with a new antagonist [3H]-RX821002, a 2-methoxy derivative of idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; In Vitro Techniques; Kinetics; Male; Membranes; Oxymetazoline; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Antinociceptive actions of alpha 2-adrenoceptor agonists in the rat spinal cord: evidence for antinociceptive alpha 2-adrenoceptor subtypes and dissociation of antinociceptive alpha 2-adrenoceptors from cyclic AMP.
Topics: Adrenergic alpha-Agonists; Animals; Benzylamines; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guanfacine; Male; Neurotoxins; Nociceptors; Pain Measurement; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1990 |
The effectiveness of alpha 2-adrenoceptor activation increases from the distal to the proximal part of the veins of canine limbs.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Dogs; Extremities; Female; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Saphenous Vein; Veins; Yohimbine | 1990 |
The role of alpha 1-adrenoceptors in adrenaline-induced hyperkalaemia.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Epinephrine; Hyperkalemia; Pericardium; Phentolamine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Swine | 1990 |
Effects of the alpha 2-adrenoceptor agonist UK14304 on pressor responses in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Drug Synergism; Norepinephrine; Phenylephrine; Prazosin; Pressoreceptors; Quinoxalines; Rats; Vasopressins; Yohimbine | 1990 |
Selective alpha 2-adrenoceptor blockade does not enhance glucose-evoked insulin release.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Brimonidine Tartrate; Dioxanes; Drug Interactions; Glucose; Idazoxan; Insulin; Male; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains | 1990 |
Alpha-adrenoceptor reserve in the canine cephalic vein.
Topics: Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Forelimb; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Veins; Yohimbine | 1990 |
An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.
Topics: Affinity Labels; Allosteric Regulation; Amino Acid Sequence; Animals; Aspartic Acid; Brimonidine Tartrate; Dioxanes; DNA Mutational Analysis; Epinephrine; Idazoxan; In Vitro Techniques; Molecular Sequence Data; Oxymetazoline; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Structure-Activity Relationship; Swine; Transfection; Yohimbine | 1990 |
In vivo and in vitro studies of alpha 2-adrenoceptor responses in human vascular smooth muscle.
Topics: Adult; Animals; Arm; Brimonidine Tartrate; Dioxanes; Dioxins; Doxazosin; Epinephrine; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasomotor System | 1985 |
Sympathetic vascular control of the pig nasal mucosa: adrenoceptor mechanisms in blood flow and volume control.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic; Regional Blood Flow; Rheology; Swine; Sympathetic Nervous System | 1989 |
Postjunctional alpha 2-adrenoceptors mediate vasoconstriction in human subcutaneous resistance vessels.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arteries; Azepines; Brimonidine Tartrate; Doxazosin; Female; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Skin; Vascular Resistance; Vasoconstriction; Veins; Yohimbine | 1989 |
Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.
Topics: Animals; Brimonidine Tartrate; Cyclic AMP; Humans; Isoquinolines; Piperazines; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine | 1989 |
Expression of functional postjunctional alpha 2-adrenoceptors in rabbit isolated distal saphenous artery--a permissive role for angiotensin II?
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arteries; Brimonidine Tartrate; Drug Interactions; In Vitro Techniques; Male; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1989 |
Hypothermia induces supersensitivity of mouse vas deferens to adrenergic agonists: evidence for postjunctional alpha 2-adrenoceptors.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Hypothermia; In Vitro Techniques; Male; Methoxamine; Mice; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Sympathomimetics; Temperature; Vas Deferens | 1989 |
Alpha-adrenoceptors and insulin release from pancreatic islets of normal and diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Diabetes Mellitus, Experimental; Dioxanes; Female; Glucose; Idazoxan; Insulin; Islets of Langerhans; Male; Phentolamine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Streptozocin; Yohimbine | 1989 |
Effects of triiodo-L-thyronine (T3)-induced hyperthyroidism on the cardiovascular alpha-adrenoceptor system in young and older rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cardiovascular System; Decerebrate State; Hyperthyroidism; Male; Myocardium; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Triiodothyronine | 1987 |
Characterization of alpha-adrenoceptors on isolated rabbit renal arterioles.
Topics: Animals; Arterioles; Brimonidine Tartrate; Dose-Response Relationship, Drug; Imidazoles; Kidney Cortex; Male; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction | 1988 |
Cooling the central ear artery of the rabbit: myogenic and adrenergic responses.
Topics: Adenosine Triphosphate; Animals; Arteries; Brimonidine Tartrate; Calcium; Cold Temperature; Ear; Electric Stimulation; Indomethacin; Male; Norepinephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Tetrodotoxin; Vasoconstriction; Yohimbine | 1988 |
A comparison of the actions of noradrenaline and UK-14,304 in the longitudinal smooth muscle of the rat isolated portal vein--no evidence for a population of post-junctional alpha 2-adrenoceptors.
Topics: Animals; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Pharmacological characterization of postsynaptic alpha-adrenoceptor subtypes in five different dog arteries in-vitro.
Topics: Animals; Antihypertensive Agents; Arteries; Brimonidine Tartrate; Cocaine; Dogs; In Vitro Techniques; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Propiophenones; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1985 |
The role of alpha-adrenoceptors in the regulation of renal tubular sodium reabsorption and renin secretion in the rabbit.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dioxanes; Guanabenz; Hemodynamics; Idazoxan; Kidney; Kidney Tubules; Male; Methoxamine; Natriuresis; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renin; Sodium | 1985 |
Evidence for existence of postjunctional alpha 1- and alpha 2-adrenoceptors in cat pulmonary vascular bed.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cats; Female; Male; Methoxamine; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Pulmonary Veins; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1985 |
Enhancement of alpha- and beta-adrenoceptor responses by elevations in vascular tone in pulmonary circulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cats; Female; Male; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propanolamines; Pulmonary Circulation; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1986 |
Heterogeneity between soluble human and rabbit splenic alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; Lectins; Oxymetazoline; Phentolamine; Prazosin; Quinolizines; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Solubility; Spleen; Sulfhydryl Reagents; Yohimbine | 1986 |
Postsynaptic alpha 1- and alpha 2-adrenergic receptors in adrenergic control of capacitance vessel tone in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Brimonidine Tartrate; Compliance; Dogs; Female; Male; Methoxamine; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Splanchnic Circulation; Splenectomy; Tyramine; Vasoconstriction; Yohimbine | 1986 |
The effect of alpha 2-adrenoceptor agonists on the acid secretory responses of rat isolated gastric mucosa to electrical field stimulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dioxanes; Electric Stimulation; Gastric Acid; Gastric Mucosa; Histamine; Idazoxan; In Vitro Techniques; Male; Pentagastrin; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains | 1986 |
Pharmacological characterization of the postsynaptic alpha-adrenoceptors in isolated canine mesenteric arteries and veins.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dogs; Dopamine; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1987 |
Characterization of the alpha-adrenoceptors mediating positive inotropy of rat left atria by use of selective agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Myocardial Contraction; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1987 |
Alpha 2-adrenoceptor-mediated responses to so-called selective alpha 1-adrenoceptor agonists after partial blockade of alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dogs; Drug Interactions; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1987 |
Direct effects of alpha 2-adrenergic receptor stimulation on intravascular systemic capacity in the dog.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Volume; Brimonidine Tartrate; Cardiopulmonary Bypass; Central Venous Pressure; Dogs; Hepatic Veins; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Tachyphylaxis; Vascular Resistance; Yohimbine | 1988 |
Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brain; Brimonidine Tartrate; Clonidine; Female; Imidazoles; In Vitro Techniques; Male; Medetomidine; Muscle, Smooth; Mydriatics; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1988 |
Inhibition of cyclic AMP production by alpha 2-adrenoceptor stimulation in the guinea-pig spinal cord slices.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Quinoxalines; Spinal Cord; Yohimbine | 1988 |
Loss of selectivity of so-called selective alpha 1-adrenoceptor agonists after phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly alpha 2.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Veins; Yohimbine | 1988 |
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Tolazoline; Yohimbine | 1985 |
Nature of alpha 1 and postjunctional alpha 2 adrenoceptors in the pulmonary vascular bed.
Topics: Animals; Azepines; Blood Pressure; Brimonidine Tartrate; Cats; Hydroxydopamines; Methoxamine; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1986 |
A study on the postjunctional excitatory alpha-adrenoreceptor subtypes in the mesenteric arterial bed of the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1986 |
Alpha adrenergic responses of blood vessels of rabbits after ovariectomy and administration of 17 beta-estradiol.
Topics: Animals; Blood Vessels; Brimonidine Tartrate; Estradiol; Female; Muscle, Smooth, Vascular; Norepinephrine; Ovariectomy; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Vasomotor System; Yohimbine | 1987 |
The contractions induced in rat and guinea-pig aortic strips by the alpha 2-adrenoceptor selective agonists B-HT 920 and UK 14,304 are mediated by alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1984 |
alpha-adrenoreceptor-mediated phasic and tonic activity in rat portal vein in vitro.
Topics: Animals; Brimonidine Tartrate; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Portal Vein; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Noradrenergic regulation of growth hormone secretion in the baboon.
Topics: Albuterol; Animals; Brimonidine Tartrate; Dose-Response Relationship, Drug; Female; Growth Hormone; Male; Papio; Practolol; Prazosin; Propanolamines; Propranolol; Quinoxalines; Receptors, Adrenergic | 1983 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Effects of three alpha 2-adrenoceptor agonists, rilmenidine, UK 14304 and clonidine on bradykinin- and substance P-induced airway microvascular leakage in guinea-pigs.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Capillaries; Capillary Permeability; Clonidine; Dioxanes; Extravascular Lung Water; Guinea Pigs; Idazoxan; Oxazoles; Prazosin; Quinoxalines; Rilmenidine; Substance P; Trachea | 1995 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Adrenoceptor-stimulated endothelium-dependent relaxation in porcine intrapulmonary arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Pulmonary Artery; Quinoxalines; Swine; Yohimbine | 1994 |
Adrenergic modulation of a spinal sympathetic reflex in the rat.
Topics: Animals; Brimonidine Tartrate; Clonidine; Male; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Spinal Cord; Sympathetic Nervous System | 1995 |
Activation of alpha-2-adrenoceptors results in an increase in F-actin formation in HIT-T15 pancreatic B-cells.
Topics: Actins; Adenoma, Islet Cell; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Biopolymers; Brimonidine Tartrate; Cytochalasins; Dioxanes; Drug Interactions; Exocytosis; Fluorescent Dyes; Gene Expression Regulation; Idazoxan; Insulin; Insulin Secretion; Islets of Langerhans; Neoplasm Proteins; Norepinephrine; Pertussis Toxin; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Effects of alpha-adrenoceptor agonists and antagonists on metabolic rate in cattle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Basal Metabolism; Body Temperature; Brimonidine Tartrate; Cattle; Clonidine; Dioxanes; Female; Guanfacine; Heart Rate; Idazoxan; Male; Prazosin; Quinoxalines | 1995 |
Regional distribution and heterogeneity of alpha-adrenoceptors in the rat and human central nervous system.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Brain; Brain Chemistry; Brimonidine Tartrate; Humans; Organ Specificity; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Species Specificity; Tritium; Yohimbine | 1993 |
Neural ATP release and its alpha 2-adrenoceptor-mediated modulation in guinea-pig vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Suramin; Vas Deferens; Yohimbine | 1993 |
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine | 1993 |
Role of alpha 1-adrenergic receptors in the intermediolateral column in mediating the pressor responses elicited by the stimulation of ventrolateral medullary pressor area.
Topics: Adrenal Glands; Adrenergic alpha-Agonists; Amino Acids; Animals; Blood Pressure; Epinephrine; Male; Mesenteric Arteries; Microinjections; Neurons; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spinal Cord; Sympathetic Nervous System | 1993 |
ANG II reverses selective inhibition of alpha 2-adrenoceptor sensitivity after in vitro isolation of arterioles.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arterioles; Brimonidine Tartrate; Histological Techniques; In Vitro Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Noradrenaline decreases transmission of NMDA- and non-NMDA-receptor mediated monosynaptic EPSPs in rat prefrontal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Antagonists; Afferent Pathways; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Methoxamine; Neurons; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Prefrontal Cortex; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
Alpha-adrenergic receptor responsiveness in vascular smooth muscle of canine bone.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Tibia; Yohimbine | 1993 |
Structure-activity relationships in prazosin-related compounds. 2. Role of the piperazine ring on alpha-blocking activity.
Topics: Adrenergic alpha-Antagonists; Animals; Hemodynamics; Male; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Inbred SHR; Stereoisomerism; Structure-Activity Relationship | 1993 |
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Epinephrine; Heart Rate; Hyperglycemia; Idazoxan; Indoles; Male; Mice; Motor Activity; Norepinephrine; Peripheral Nerves; Prazosin; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction | 1993 |
Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Indoles; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Prazosin; Quinoxalines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Dopaminergic and alpha-adrenergic control of neurotransmission in human right atrium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Benzazepines; Brimonidine Tartrate; Domperidone; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Ergolines; Female; Fenoldopam; Heart Atria; Humans; In Vitro Techniques; Male; Methoxamine; Middle Aged; Norepinephrine; Prazosin; Quinoxalines; Quinpirole; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Synaptic Transmission; Yohimbine | 1995 |
Receptor binding profile of cyclazosin, a new alpha 1B-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Male; Prazosin; Quinazolines; Quinoxalines; Rats; Receptors, Adrenergic, alpha-1 | 1995 |
Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro.
Topics: Acetylcholine; Adrenergic Agonists; Adrenergic Antagonists; Animals; Atropine; Brimonidine Tartrate; Calcium Channel Blockers; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Horses; Isoproterenol; Jejunum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Quinoxalines; Sympathetic Nervous System; Tetrodotoxin; Verapamil; Yohimbine | 1996 |
The actions of medetomidine may not be mediated exclusively by alpha 2-adrenoceptors in the equine saphenous vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Female; Horses; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Structure-Activity Relationship | 1996 |
Low concentrations of angiotensin II unmask vasoconstrictory alpha 2-adrenoceptors in isolated perfused kidneys of spontaneously hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Dioxanes; Dose-Response Relationship, Drug; Hypertension; Idazoxan; Imidazoles; Kidney; Methoxamine; Perfusion; Prazosin; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1995 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
Clonidine-induced increase in osmolar clearance and free water clearance via activation of two distinct alpha 2-adrenoceptor sites.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Male; Naltrexone; Osmolar Concentration; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Water | 1996 |
Characterization of alpha-adrenoceptor subtype(s) mediating vasoconstriction in the perfused rabbit ovarian vascular bed.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Female; Ovary; Oxidopamine; Perfusion; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1996 |
Adrenergic responses in silent and putative inhibitory pacemaker-like neurons of the rat rostral ventrolateral medulla in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Bicuculline; Biological Clocks; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; Interneurons; Ion Channel Gating; Isoproterenol; Medulla Oblongata; Norepinephrine; Prazosin; Quinoxalines; Rats; Rats, Wistar; Strychnine; Synaptic Transmission; Tetrodotoxin; Yohimbine | 1997 |
Alpha-2a/d adrenoceptor subtype stimulation by guanfacine increases osmolar clearance.
Topics: Adrenergic alpha-Agonists; Animals; Body Water; Brimonidine Tartrate; Guanfacine; Idazoxan; Kidney; Male; Naltrexone; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1997 |
Subtype determination of soma-dendritic alpha2-autoreceptors in slices of rat locus coeruleus.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Dendrites; In Vitro Techniques; Locus Coeruleus; Maprotiline; Neurons; Norepinephrine; Phentolamine; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1997 |
Alpha-adrenoceptors in equine digital veins: evidence for the presence of both alpha1 and alpha2-receptors mediating vasoconstriction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dopamine; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Veins; Yohimbine | 1997 |
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1997 |
Voltage-dependent calcium currents in bulbospinal neurons of neonatal rat rostral ventrolateral medulla: modulation by alpha2-adrenergic receptors.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Brimonidine Tartrate; Calcium; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Fluorescent Dyes; Ion Channel Gating; Medulla Oblongata; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Prazosin; Propranolol; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Spider Venoms; Tyrosine 3-Monooxygenase | 1998 |
alpha2-Adrenoceptor-mediated potassium currents in acutely dissociated rat locus coeruleus neurones.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane Permeability; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoquinolines; Kinetics; Locus Coeruleus; Membrane Potentials; Neurons; Nystatin; Patch-Clamp Techniques; Piperazines; Potassium; Potassium Channel Blockers; Potassium Channels; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Thionucleotides; Yohimbine | 1998 |
The expression of functional postsynaptic alpha2-adrenoceptors in the corpus cavernosum smooth muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Cyclic AMP; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Penis; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Synapses; Tritium; Yohimbine | 1998 |
Alpha-adrenoceptor subtypes of dog saphenous vein: another unusual property.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Dogs; Female; Fluorescence; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Signal Transduction; Yohimbine | 1998 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Norepinephrine increases cyclic GMP levels in cerebellar cells from neuronal nitric oxide synthase knockout mice.
Topics: Animals; Astrocytes; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Mice; Mice, Knockout; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Norepinephrine; Oxadiazoles; Prazosin; Quinoxalines; Sympatholytics; Sympathomimetics | 1998 |
Heterogeneous effects of rapid eye movement sleep deprivation on binding to alpha- and beta-adrenergic receptor subtypes in rat brain.
Topics: Animals; Autoradiography; Brain; Brimonidine Tartrate; Iodine Radioisotopes; Kinetics; Male; Organ Specificity; Pindolol; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Deprivation; Sleep, REM; Tritium | 1998 |
Alpha2-adrenoceptors mediate the effect of dopamine on adult rat jejunal electrolyte transport.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiloride; Animals; Brimonidine Tartrate; Bucladesine; Cardiotonic Agents; Colforsin; Diuretics; Dopamine; Dose-Response Relationship, Drug; Electric Impedance; Electrolytes; Furosemide; Ion Transport; Jejunum; Male; Ouabain; Phentolamine; Prazosin; Propranolol; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2 | 1998 |
Insights into the unusual alpha adrenoceptor subtype in dog saphenous vein using phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1999 |
Impaired function of alpha-2 adrenoceptors in smooth muscle of mesenteric arteries from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apamin; Biological Factors; Brimonidine Tartrate; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Prazosin; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-2 | 1998 |
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine | 1998 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Importance of agonists in alpha-adrenoceptor classification and localisation of alpha1-adrenoceptors in human prostate.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Brimonidine Tartrate; Calcium; Carotid Artery, Common; Cells, Cultured; Fibroblasts; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prazosin; Prostate; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Saphenous Vein | 1999 |
Effects of some imidazolidine alpha2-adrenoceptor agonists in rat isolated atria.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Electric Stimulation; Female; Heart Atria; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Muscle Contraction; Norepinephrine; Pargyline; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 1999 |
Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.
Topics: Adrenergic Antagonists; Anesthesia; Aniline Compounds; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Femoral Artery; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Perfusion; Phenylephrine; Piperidines; Prazosin; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilator Agents; Yohimbine | 1999 |
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Gene Expression; Humans; Hydrogen-Ion Concentration; Imidazoles; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Tetrahydronaphthalenes; Yohimbine | 2000 |
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Calcium; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Estrenes; Fluorescence; Gene Expression; Humans; Imidazoles; Norepinephrine; Prazosin; Pyrrolidinones; Quinoxalines; Radioligand Assay; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Tetrahydronaphthalenes; Thapsigargin; Xanthenes; Yohimbine | 2000 |
Effect of norepinephrine receptors on trigeminal rhythm generation in newborn rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Brimonidine Tartrate; Idazoxan; Mastication; Motor Neurons; N-Methylaspartate; Neural Pathways; Norepinephrine; Organ Culture Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Trigeminal Nuclei | 2000 |
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 2001 |
Searching for cyclazosin analogues as alpha(1B)-adrenoceptor antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Binding Sites; CHO Cells; Clone Cells; Cricetinae; Guinea Pigs; Humans; Male; Prazosin; Quinazolines; Quinoxalines; Rats; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 2003 |
In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors | 2003 |
Norepinephrine activates extracellular-regulated kinase in cortical neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Brimonidine Tartrate; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Extracellular Space; Female; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Neurons; Norepinephrine; Pertussis Toxin; Phosphorylation; Prazosin; Pregnancy; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2003 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
alpha1-Adrenergic modulation of synaptic input to Purkinje neurons in rat cerebellar brain slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Animals, Newborn; Cerebellum; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Norepinephrine; Patch-Clamp Techniques; Phentolamine; Phenylephrine; Picrotoxin; Prazosin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Synapses; Tetrodotoxin; Time Factors | 2005 |
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Enaminones and norepinephrine employ convergent mechanisms to depress excitatory synaptic transmission in the rat nucleus accumbens in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cyclohexanes; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Nucleus Accumbens; Phosphinic Acids; Prazosin; Propanolamines; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2006 |
Presynaptic alpha-adrenoceptors in median preoptic nucleus modulate inhibitory neurotransmission from subfornical organ and organum vasculosum lamina terminalis.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cells, Cultured; Hypothalamus; Idazoxan; Imidazoles; Isoproterenol; Norepinephrine; Prazosin; Preoptic Area; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Signal Transduction; Subfornical Organ | 2007 |
Synthesis and alpha(1)-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Binding, Competitive; Furans; Male; Molecular Structure; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 2007 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Brain Chemistry; Brimonidine Tartrate; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Motivation; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Self Administration; Septal Nuclei | 2008 |
Role of alpha1-adrenoceptor subtypes in the effects of methylenedioxy methamphetamine (MDMA) on body temperature in the mouse.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Body Temperature; Fever; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-1; Thymine | 2008 |
Noradrenergic control of odor recognition in a nonassociative olfactory learning task in the mouse.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Association Learning; Benzopyrans; Benzylamines; Brimonidine Tartrate; Imidazoles; Male; Mental Recall; Mice; Mice, Inbred C57BL; Norepinephrine; Odorants; Prazosin; Propranolol; Quinoxalines; Recognition, Psychology; Smell | 2007 |
Noradrenergic vasoconstriction of pig prostatic small arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Arteries; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; In Vitro Techniques; Indoles; Male; Norepinephrine; Piperazines; Prazosin; Prostate; Quinoxalines; Swine; Thymine; Vasoconstriction; Yohimbine | 2008 |
Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain; Cell Line; Dantrolene; Dogs; Imidazoles; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Prazosin; Quinoxalines; Swine; Testis; Triamterene; Xenobiotics | 2008 |
Differential effects of prazosin and naftopidil on pelvic blood flow and nitric oxide synthase levels in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Hypertension; Male; Naphthalenes; Nitric Oxide Synthase; Pelvis; Penis; Piperazines; Prazosin; Prostate; Quinazolines; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Regional Blood Flow; Urinary Bladder | 2008 |
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2009 |
Regional heterogeneity of α-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Arterioles; Brimonidine Tartrate; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle, Skeletal; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2010 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Imidazoles; In Vitro Techniques; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Piperazines; Prazosin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Serotonin; Tail; Temperature; Vasoconstriction; Yohimbine | 2010 |
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Guanfacine; Imidazoles; Imidazoline Receptors; Isoquinolines; Male; Motor Activity; Naphthyridines; Prazosin; Propranolol; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2011 |
The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Idazoxan; Male; Methoxamine; Movement; Neurons; Norepinephrine; Nucleus Accumbens; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2012 |
Contribution of α-adrenoceptor stimulation by phenylephrine to basal nitric oxide production in the isolated mouse aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Yohimbine | 2013 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |
Partial agonist activity of α1-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3.
Topics: Adrenergic alpha-1 Receptor Antagonists; beta-Arrestins; Binding Sites; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Humans; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Nuclear Magnetic Resonance, Biomolecular; Prazosin; Quinazolines; Quinoxalines; Receptors, CXCR; Receptors, CXCR4 | 2018 |
Both α
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Thymine; Yohimbine | 2021 |