quinoxalines has been researched along with phenylephrine in 160 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (21.25) | 18.7374 |
| 1990's | 54 (33.75) | 18.2507 |
| 2000's | 52 (32.50) | 29.6817 |
| 2010's | 18 (11.25) | 24.3611 |
| 2020's | 2 (1.25) | 2.80 |
| Authors | Studies |
|---|---|
| Baird, M; Daly, CJ; Gordon, JF; McGrath, JC | 1 |
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Guimarães, JT; Guimarães, S; Moura, D; Nunes, JP; Vaz-da-Silva, MJ | 1 |
| Minneman, KP; Wilson, KM | 1 |
| Dunn, WR; McGrath, JC; Wilson, VG | 1 |
| Bültmann, R; Starke, K; von Kügelgen, I | 1 |
| Lepor, H | 1 |
| Bauer, BA; Bove, AA; Brum, JM; Miller, TD; Rogers, PJ; Vanhoutte, PM | 1 |
| Abe, K; Matsuki, N; Saito, H | 1 |
| Carrasco, VN; Faber, JE; Pillsbury, HC; Prazma, J; Triana, RJ | 1 |
| Guimaraes, S; Nunes, JP | 2 |
| Rand, MJ; Xiao, XH | 2 |
| Boulanger, C; Flavahan, NA; Katusic, ZS; Komori, K; Vanhoutte, PM; Vos, AA | 1 |
| Dettmar, PW; Downing, OA; Roach, AG; Urquhart, CJ; Williams, RJ; Wilson, KA | 1 |
| Guimarães, S; Moura, D; Vaz-da-Silva, MJ | 1 |
| MacLean, MR; McGrath, JC | 1 |
| Calvete, J; Hayes, R; Sever, PS; Thom, S | 1 |
| Armstead, WM; Hyman, AL; Kadowitz, PJ; Lippton, HL | 1 |
| Baumann, M; Gup, DI; Lepor, H; Shapiro, E | 1 |
| Lacroix, JS; Lundberg, JM | 1 |
| Alden, BM; Matherne, GP; Nakamura, KT; Robillard, JE; Rusch, NJ | 1 |
| Edwards, RM; Trizna, W | 1 |
| Hinton, CF; White, JF | 1 |
| Daly, CJ; McGrath, JC; Wilson, VG | 2 |
| Feder, HH; Vincent, PA | 1 |
| Guimarães, S; Paiva, MQ; Polónia, JJ | 1 |
| Honda, K; Miyata-Osawa, A; Shiono, K; Takenaka, T; Terai, M | 1 |
| Hesse, IF; Johns, EJ | 1 |
| Hyman, AL; Kadowitz, PJ | 2 |
| Gesek, FA; Strandhoy, JW; Wolff, DW | 1 |
| Itoh, H; Kohli, JD; Rajfer, SI | 1 |
| Broadley, KJ; Williamson, KL | 1 |
| Guimarães, S; Moura, D; Paiva, MQ | 1 |
| Armstead, WM; Hyman, AL; Kadowitz, PJ; Lippton, HL; Roland, PY | 1 |
| Gonçalves, J; Guimarães, S; Nunes, JP; Paiva, MQ | 1 |
| Faber, JE; Gettes, DR; Gianturco, DP | 1 |
| Hair, WM; Hughes, AD; Martin, GN; Nielsen, H; Schachter, M; Sever, PS; Thom, SA | 1 |
| Miller, VM; Vanhoutte, PM | 1 |
| Flavahan, NA; Vanhoutte, PM | 1 |
| Hyman, AL; Kadowitz, PJ; Lippton, HL | 1 |
| Pipili, E | 1 |
| Flavahan, NA; Gisclard, V; Vanhoutte, PM | 1 |
| Aarhus, LL; Flavahan, NA; Miller, VM; Vanhoutte, PM | 1 |
| Bradshaw, CM; Sheridan, RD; Szabadi, E | 1 |
| Shepperson, NB | 1 |
| Bogaert, MG; Lefebvre, RA; Verplanken, PA | 1 |
| Hicks, PE | 1 |
| Deth, RC; Jinsi, A | 1 |
| Hara, M; Inoue, M; Irie, T; Mikami, T; Mikami, Y; Minato, A; Omori, K; Uyama, M; Yasukura, T; Zeng, XT | 1 |
| Crowley, WR; Parker, SL | 1 |
| Ferrell, WR; Najafipour, H | 1 |
| Faber, JE; Ikeoka, K | 1 |
| Crepel, F; Hirsch, JC; Law-Tho, D | 1 |
| Faber, JE; Tateishi, J | 1 |
| Deth, RC; Waen-Safranchik, VI | 1 |
| MacLean, MR; McCulloch, KM; McGrath, JC | 1 |
| Soares-da-Silva, P | 1 |
| Ichihara, K; Mori, H; Nagasaka, M; Okumura, K | 1 |
| Diadori, A; Schütte, M; Wang, C; Wolosin, JM | 1 |
| Brown, DR; Malone, ED; Trent, AM; Turner, TA | 1 |
| Bryant, CE; Clarke, KW | 1 |
| Bandler, R; Christie, MJ; Vaughan, CW | 1 |
| Drewett, JG; Herzig, TC; Knych, ET; Olson, LJ | 1 |
| Brown, JC; Burns, DM; Dykes, EL; Flitney, FW; Hirst, DG; Kennovin, GD; Ruddock, MW | 1 |
| Dresner, LS; Mueller, CM; Ponomarenko, IN; Wait, RB; Wang, SP; West, MW | 1 |
| Elliott, J | 1 |
| Kimura, M; Ogihara, M | 3 |
| Krassioukov, AV; Krenz, NR; Maiorov, DN; Weaver, LC | 1 |
| Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Kanagy, NL | 1 |
| Gallant, CM; Goldstein, I; Gupta, S; Moreland, RB; Traish, A; Yang, S | 1 |
| Kwan, CY; Mo, FM | 1 |
| Abysique, A; Bouvier, M; Orsoni, P | 1 |
| Mifflin, SW; Zhang, J | 1 |
| Freitag, A; Racké, K; Wessler, I | 1 |
| Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR | 1 |
| Hagiwara, T; Kiyose, M; Kobayashi, Y; Kumasaka, S; Muldoon, SM; Okabe, E | 1 |
| Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
| Daniel, EE; Kwan, CY; Loke, JC; Low, AM; Lu-Chao, H | 1 |
| Ali, Z; Campbell, JN; Chien, HF; Flavahan, NA; Hartke, TV; Meyer, RA; Ringkamp, M | 1 |
| Daly, CJ; Mackenzie, JF; McGrath, JC; Naghadeh, MA; Pediani, JD | 1 |
| Fujiki, H; Imaizumi, T; Kambayashi, J; Kimura, Y; Kishi, M; Mori, T; Orito, K; Shimizu, H; Tanaka, M; Teramoto, S; Tominaga, M; Yoshida, K | 1 |
| Chotani, MA; Daunt, D; Flavahan, NA; Flavahan, S; Mitra, S | 1 |
| Jiang, F; Li, CG; Rand, MJ | 1 |
| Flavahan, NA; Flavahan, S; Liu, Q; Spence, RJ; Tidmore, W; Wiener, CM; Wigley, FM; Wu, S | 1 |
| Butler, AR; Mazzei, FA; Megson, IL; Miller, MR; Roseberry, MJ; Webb, DJ | 2 |
| Iida, S; Ishihama, K; Kogo, M; Koizumi, H; Matsuya, T; Mori, A; Tanaka, S | 1 |
| Ikeo, T; Inoue, H; Kikkawa, K; Mochida, H; Noto, T; Takagi, M; Yano, K | 1 |
| Fuchs, PN; Meyer, RA; Raja, SN | 1 |
| Ratz, PH | 1 |
| Hillier, C; Jarajapu, YP; MacDonald, A | 1 |
| Bendhack, LM; Ceron, PI; Cremonez, DC; Tedesco, AC | 1 |
| Akerman, S; Goadsby, PJ; Hill, RG; Williamson, DJ | 1 |
| Brioni, JD; Hsieh, GC; Kolasa, T; Sullivan, JP | 1 |
| Barron, LA; Giardina, JB; Granger, JP; Khalil, RA | 1 |
| Adler-Graschinsky, E; Boric, MP; Figueroa, XF; Huidobro-Toro, JP; Mendizábal, VE; Poblete, MI | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Parvez, H | 1 |
| Alexander, BT; Davis, JR; Giardina, JB; Granger, JP; Green, GM; Khalil, RA | 1 |
| Bishai, JM; Buchholz, JN; Gheorghe, CP; Longo, LD; Meulenaar, R; Nijland, R; Penninga, L; Zhang, L; Zhao, Y | 1 |
| Abraham, E; Arcaroli, J; Kupfner, J; Park, JS; Pitts, TM; Strassheim, D; Yang, KY; Yum, HK | 1 |
| Beretta, C; Carcano, R; Cavalli, M | 1 |
| Castillo, C; Castillo, EF; Gil-Gastelum, O; López, O; Medina, R | 1 |
| Brioni, JD; Hsieh, GC; Moreland, RB; O'Neill, AB; Sullivan, JP | 1 |
| Connell, BJ; Saleh, TM | 1 |
| Chen, KH; Chen, SJ; Webb, RC; Wu, CC; Yen, MH | 1 |
| Hobbs, AJ; MacAllister, RJ; Madhani, M; Scotland, RS | 1 |
| Ishiguro, S; Miyamoto, A; Nishio, A; Takagi, T; Yamazaki, Y | 1 |
| Ambrosio, SR; da Costa, FB; de Oliveira, AM; Tirapelli, CR | 1 |
| Antunes, E; Baracat, JS; De Nucci, G; de Oliveira, JF; Fregonesi, A; Okuyama, CE; Priviero, FB; Rodrigues Netto, N; Teixeira, CE | 1 |
| Feldman, S; Weidenfeld, J | 1 |
| Khalil, RA; Orshal, JM | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Arroyo, A; Daftary, A; Gandley, RE; Harger, G; Huang, W; Hubel, CA; Jiang, J; Kagan, VE; Pitt, B; Taylor, RN; Tyurin, VA | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Martínez, AC; Prieto, D; Recio, P; Rivera, L | 1 |
| Altura, BM; Altura, BT; Li, J; Li, W | 1 |
| Jin, L; Palmer, T; Priviero, FB; Teixeira, CE; Webb, RC; Ying, Z | 1 |
| Grenegård, M; Gunnarsson, P; Lindström, E; Persson, AA | 1 |
| Brockhaus, J; Deitmer, JW; Hecker, C; Herold, S | 1 |
| Berkowitz, DE; Champion, HC; Hare, JM; Li, D; Nyhan, D; Ryoo, S; Shoukas, AA; Steppan, J; Wang, D; White, AR | 1 |
| de Godoy, MA; de Oliveira, AM; Fukada, SY; Tirapelli, CR | 1 |
| Castillo, C; Castillo, EF; López, RM; Ortíz, CS; Ruíz, A; Vélez, JM | 1 |
| Bakker, LM; Chaytor, AT; Edwards, DH; Griffith, TM | 1 |
| Bagcivan, I; Berkan, O; Doğan, K; Kaya, T; Yildirim, K; Yildirim, S | 1 |
| Han, SH; Hong, S; Kim, CY; Seong, GJ | 1 |
| Jiang, B; Wang, R; Wu, L | 1 |
| Sartor, DM; Verberne, AJ | 1 |
| Bendhack, LM; Rocha, ML | 1 |
| Bose, R; Cheng, ZQ; Jacobs, H; Kasian, K; Light, RB; Mink, SN; Santos Martinez, LE | 1 |
| Dehpour, AR; Ghahremani, MH; Ghasemi, M; Karimollah, AR | 1 |
| Chen, QZ; Gao, PJ; Guo, SJ; Han, WQ; Wu, LY; Zhu, DL | 1 |
| Jewelewicz, DA; Liebmann, J; Radcliffe, NM; Ritch, R | 1 |
| Araújo, IG; Athayde-Filho, P; Cavalcante, KV; Correia, Nde A; Dias, KL; Lira, BF; Medeiros, IA; Silva, DF; Silva-Filho, JC | 1 |
| Goto, K; Ishikawa, T; Kashihara, T; Nakayama, K; Sahara, Y | 1 |
| Blanco, CE; Villamor, E; Zoer, B | 1 |
| Jokanović, M; Micov, A; Savić, V; Simić, M; Stepanović, JM; Stepanović-Petrović, RM; Tokic-Vujosević, Z; Tomić, MA | 1 |
| Castillo, C; Castillo, EF; López, RM; Pérez, T | 1 |
| Jackson, WF; Moore, AW; Segal, SS | 1 |
| Bendhack, LM; da Silva, RS; Ford, PC; Pereira, Ade C | 1 |
| Deng, J; Feng, E; Huang, H; Jiang, H; Li, H; Li, J; Liu, H; Liu, X; Ma, S; Miao, L; Shen, X; Zhang, Y; Zhu, J; Zhu, W | 1 |
| Kimura, M; Moteki, H; Ogihara, M | 1 |
| Bak, YO; Choi, BR; Jeon, JH; Kim, HK; Lee, SW; Park, JK; So, I; Zhao, C | 1 |
| Gupta, A; Kekunnaya, R; Rao, HL; Sachdeva, V | 1 |
| Deng, J; Jiang, HL; Li, J; Ma, S; Miao, LY; Xue, L; Zhang, Y; Zhu, J; Zhu, WL | 1 |
| Athayde-Filho, PF; Braga, VA; França, KC; França-Silva, MS; Luciano, MN; Medeiros, IA; Nakao, LS; Ribeiro, TP; Santos, AF; Silva, JS | 1 |
| Akinfieva, OV; Artem'eva, MM; Daliger, IL; Medvedev, OS; Medvedeva, NA; Postnikov, AB; Shevelev, SA | 1 |
| Kang, YH; Morgan, KG; Shin, HM; Yang, IJ | 1 |
| Bult, H; De Meyer, GR; Fransen, P; Martinet, W; Schrijvers, DM; Van Hove, CE; van Langen, JT | 1 |
| Andrade E Silva, ML; Bastos, JK; Carvalho, MT; Celotto, AC; Cunha, WR; Evora, PR; Rezende, KC | 1 |
| Cuong, NM; Dung, PT; Durante, M; Fusi, F; Nam, NH; Sgaragli, G | 1 |
| Kang, P; Kim, HK; Lee, JM; Ryu, KH; Seol, GH | 1 |
| Birulina, YG; Gusakova, SV; Kovalev, IV; Nosarev, AV; Petrova, IV; Rydchenko, VS; Smagliy, LV; Yartseva, YO | 1 |
| Alsufyani, HA; Docherty, JR; McCormick, PA | 1 |
| Gao, WC; Li, X; Ma, X; Pang, PP; Peng, LC; Yang, L; Zheng, CB | 1 |
1 review(s) available for quinoxalines and phenylephrine
| Article | Year |
|---|---|
Role of alpha-adrenergic blockers in the treatment of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Carbachol; Humans; Male; Muscle Contraction; Phenylephrine; Prazosin; Prostatic Hyperplasia; Quinoxalines | 1990 |
2 trial(s) available for quinoxalines and phenylephrine
| Article | Year |
|---|---|
Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analysis of Variance; Brimonidine Tartrate; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Nociceptors; Norepinephrine; Pain Threshold; Phenylephrine; Quinoxalines; Receptors, Adrenergic; Skin; Vasoconstrictor Agents | 2001 |
Effect of prophylactic brimonidine instillation on bleeding during strabismus surgery in adults.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Brimonidine Tartrate; Conjunctival Diseases; Double-Blind Method; Eye Hemorrhage; Female; Humans; Hyaluronic Acid; Male; Oculomotor Muscles; Phenylephrine; Premedication; Quinoxalines; Strabismus | 2007 |
157 other study(ies) available for quinoxalines and phenylephrine
| Article | Year |
|---|---|
Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Electric Stimulation; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phenylephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Synaptic Transmission | 1992 |
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
Alpha 1- and alpha 2-adrenoceptors at different levels of the canine saphenous vein.
Topics: Animals; Brimonidine Tartrate; Dioxanes; Dogs; Electric Stimulation; Epinephrine; In Vitro Techniques; Inositol; Inositol Phosphates; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Synapses; Yohimbine | 1991 |
Synergistic interactions between alpha 1- and alpha 2-adrenergic receptors in activating 3H-inositol phosphate formation in primary glial cell cultures.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Cells, Cultured; Dose-Response Relationship, Drug; Inositol Phosphates; Neuroglia; Norepinephrine; Osmolar Concentration; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Time Factors; Tritium; Yohimbine | 1991 |
Postjunctional alpha-adrenoceptors in the rabbit isolated distal saphenous artery: indirect sensitivity to prazosin of responses to noradrenaline mediated via postjunctional alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine | 1991 |
Exercise training and responsiveness of isolated coronary arteries.
Topics: Animals; Brimonidine Tartrate; Coronary Vessels; Dogs; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Physical Exertion; Quinoxalines; Substance P; Vasodilation | 1991 |
Changes in intracellular free Ca2+ concentration by activation of alpha-adrenoceptors in rat tail artery.
Topics: Adrenergic alpha-Agonists; Animals; Arteries; Benzofurans; Brimonidine Tartrate; Calcium; Fura-2; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Regional Blood Flow; Tail; Vasoconstriction | 1990 |
Cochlear microcirculation. Effect of adrenergic agonists on arteriole diameter.
Topics: Adrenergic alpha-Agonists; Animals; Arterioles; Brimonidine Tartrate; Cochlea; Gerbillinae; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Videotape Recording | 1990 |
The effectiveness of alpha 2-adrenoceptor activation increases from the distal to the proximal part of the veins of canine limbs.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Dogs; Extremities; Female; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Saphenous Vein; Veins; Yohimbine | 1990 |
Effects of the alpha 2-adrenoceptor agonist UK14304 on pressor responses in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Drug Synergism; Norepinephrine; Phenylephrine; Prazosin; Pressoreceptors; Quinoxalines; Rats; Vasopressins; Yohimbine | 1990 |
Effect of CRL 41034 on the adrenergic neuroeffector interaction in the canine saphenous vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dogs; Electric Stimulation; Female; Isometric Contraction; Male; Norepinephrine; Phenylephrine; Piperidines; Pyrrolidines; Quinoxalines; Saphenous Vein | 1990 |
Alpha 2-adrenoceptor antisecretory responses in the rat jejunum.
Topics: Animals; Body Fluids; Brimonidine Tartrate; Dioxanes; Electric Stimulation; Electrolytes; Idazoxan; In Vitro Techniques; Jejunum; Male; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrodotoxin; Theophylline | 1990 |
Alpha-adrenoceptor reserve in the canine cephalic vein.
Topics: Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Forelimb; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Veins; Yohimbine | 1990 |
Effects of pre-contraction with endothelin-1 on alpha 2-adrenoceptor- and (endothelium-dependent) neuropeptide Y-mediated contractions in the isolated vascular bed of the rat tail.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Cholic Acids; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Tail; Yohimbine | 1990 |
In vivo and in vitro studies of alpha 2-adrenoceptor responses in human vascular smooth muscle.
Topics: Adult; Animals; Arm; Brimonidine Tartrate; Dioxanes; Dioxins; Doxazosin; Epinephrine; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasomotor System | 1985 |
Influence of nisoldipine on vascular resistance and vasoconstrictor responses in cats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Azepines; Blood Pressure; Brimonidine Tartrate; Cardiac Output; Cats; Dinoprost; Dioxanes; Electric Stimulation; Female; Idazoxan; Male; Methoxamine; Nifedipine; Nisoldipine; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Quinoxalines; Splanchnic Circulation; Sulfonamides; Sympathetic Nervous System; Tyramine; Vascular Resistance; Vasoconstriction | 1987 |
Contractile properties of human prostate adenomas and the development of infravesical obstruction.
Topics: Aged; Brimonidine Tartrate; Carbachol; Humans; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Prostatic Hyperplasia; Quinoxalines; Sensory Receptor Cells; Urinary Bladder Neck Obstruction | 1989 |
Sympathetic vascular control of the pig nasal mucosa: adrenoceptor mechanisms in blood flow and volume control.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic; Regional Blood Flow; Rheology; Swine; Sympathetic Nervous System | 1989 |
Regional variation of postjunctional alpha-adrenoceptor responses in the developing renal vascular bed of sheep.
Topics: Age Factors; Animals; Animals, Newborn; Brimonidine Tartrate; Fetus; Guanabenz; Isometric Contraction; Kidney; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Renal Artery; Renal Veins; Sheep; Vasoconstriction | 1989 |
Alpha 2-adrenoceptor agonists enhance vasoconstrictor responses to alpha 1-adrenoceptor agonists in the rat tail artery by increasing the influx of Ca2+.
Topics: Adrenergic alpha-Agonists; Animals; Arteries; Brimonidine Tartrate; Calcium; Diltiazem; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Perfusion; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Regional Blood Flow; Tail; Tetrahydronaphthalenes; Vasoconstriction | 1989 |
Characterization of alpha-adrenoceptors on isolated rabbit renal arterioles.
Topics: Animals; Arterioles; Brimonidine Tartrate; Dose-Response Relationship, Drug; Imidazoles; Kidney Cortex; Male; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction | 1988 |
Alpha 2-receptors mediate catecholamine-stimulated acid secretion in Amphiuma jejunum.
Topics: Animals; Brimonidine Tartrate; Clonidine; In Vitro Techniques; Jejunum; Methoxamine; Norepinephrine; Phenylephrine; Propranolol; Protons; Quinoxalines; Receptors, Adrenergic, alpha; Stimulation, Chemical; Urodela | 1988 |
An examination of the postjunctional alpha-adrenoceptor subtypes for (-)-noradrenaline in several isolated blood vessels from the rabbit.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Brimonidine Tartrate; Ear; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renal Veins; Saphenous Vein; Stereoisomerism; Yohimbine | 1988 |
Alpha-1- and alpha-2-noradrenergic receptors modulate lordosis behavior in female guinea pigs.
Topics: Animals; Brimonidine Tartrate; Female; Guinea Pigs; Methoxamine; Ovariectomy; Phenylephrine; Quinoxalines; Receptors, Adrenergic; Sexual Behavior, Animal | 1988 |
Pharmacological characterization of postsynaptic alpha-adrenoceptor subtypes in five different dog arteries in-vitro.
Topics: Animals; Antihypertensive Agents; Arteries; Brimonidine Tartrate; Cocaine; Dogs; In Vitro Techniques; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Propiophenones; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1985 |
Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Brain; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Pulmonary Artery; Quinoxalines; Rabbits; Rats; Receptors, Adrenergic, alpha; Sulfonamides; Tritium; Vas Deferens | 1985 |
The role of alpha-adrenoceptors in the regulation of renal tubular sodium reabsorption and renin secretion in the rabbit.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dioxanes; Guanabenz; Hemodynamics; Idazoxan; Kidney; Kidney Tubules; Male; Methoxamine; Natriuresis; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renin; Sodium | 1985 |
Evidence for existence of postjunctional alpha 1- and alpha 2-adrenoceptors in cat pulmonary vascular bed.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cats; Female; Male; Methoxamine; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Pulmonary Veins; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1985 |
Enhancement of alpha- and beta-adrenoceptor responses by elevations in vascular tone in pulmonary circulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cats; Female; Male; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propanolamines; Pulmonary Circulation; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1986 |
In vivo assessment of rat renal alpha adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Guanabenz; Homeostasis; Imidazoles; Kidney; Male; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Ultrasonography; Vasoconstriction | 1987 |
Pharmacological characterization of the postsynaptic alpha-adrenoceptors in isolated canine mesenteric arteries and veins.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Dogs; Dopamine; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1987 |
Characterization of the alpha-adrenoceptors mediating positive inotropy of rat left atria by use of selective agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Myocardial Contraction; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1987 |
Alpha 2-adrenoceptor-mediated responses to so-called selective alpha 1-adrenoceptor agonists after partial blockade of alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dogs; Drug Interactions; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1987 |
Inhibitory effects of diltiazem on vasoconstrictor responses in the cat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Cats; Diltiazem; Electric Stimulation; Female; Male; Methoxamine; Norepinephrine; Phenylephrine; Potassium Chloride; Quinoxalines; Tyramine; Vasoconstriction | 1988 |
Loss of selectivity of so-called selective alpha 1-adrenoceptor agonists after phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly alpha 2.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Veins; Yohimbine | 1988 |
Microvascular effects of atrial natriuretic factor: interaction with alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Arterioles; Atrial Natriuretic Factor; Brimonidine Tartrate; Microcirculation; Norepinephrine; Osmolar Concentration; Phenylephrine; Quinoxalines; Vasoconstriction; Vasodilation; Venules | 1988 |
Size and site-dependent heterogeneity of human vascular responses in vitro.
Topics: Arteries; Atrial Natriuretic Factor; Azepines; Brimonidine Tartrate; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Neuropeptide Y; Neuropeptides; Phenylephrine; Quinoxalines; Vascular Resistance; Vasoactive Intestinal Peptide | 1988 |
Endothelial alpha 2-adrenoceptors in canine pulmonary and systemic blood vessels.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Dogs; Endothelium; Female; In Vitro Techniques; Isometric Contraction; Lung; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Pulmonary Artery; Pulmonary Veins; Quinoxalines; Receptors, Adrenergic, alpha | 1985 |
Alpha-1 and alpha-2 adrenoceptor: response coupling in canine saphenous and femoral veins.
Topics: Animals; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Female; Femoral Vein; Imidazoles; Male; Mathematics; Norepinephrine; Phenoxybenzamine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein | 1986 |
Nature of alpha 1 and postjunctional alpha 2 adrenoceptors in the pulmonary vascular bed.
Topics: Animals; Azepines; Blood Pressure; Brimonidine Tartrate; Cats; Hydroxydopamines; Methoxamine; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Propranolol; Pulmonary Artery; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1986 |
A study on the postjunctional excitatory alpha-adrenoreceptor subtypes in the mesenteric arterial bed of the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1986 |
Alpha adrenergic responses of blood vessels of rabbits after ovariectomy and administration of 17 beta-estradiol.
Topics: Animals; Blood Vessels; Brimonidine Tartrate; Estradiol; Female; Muscle, Smooth, Vascular; Norepinephrine; Ovariectomy; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Vasomotor System; Yohimbine | 1987 |
Denervation augments alpha-2 but not alpha-1 adrenergic responses in canine saphenous veins.
Topics: Animals; Brimonidine Tartrate; Denervation; Dogs; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasomotor System | 1987 |
Neuronal responses to noradrenaline in the cerebral cortex: evidence against the involvement of alpha 2-adrenoceptors.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Dioxanes; Idazoxan; Male; Neurons; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Alpha 2-adrenoceptor agonists potentiate responses mediated by alpha 1-adrenoceptors in the cat nictitating membrane.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nictitating Membrane; Norepinephrine; Phenylephrine; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha | 1984 |
Pharmacological characterization of alpha adrenoceptors in the rat gastric fundus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Methacholine Compounds; Muscle Contraction; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha | 1984 |
alpha-adrenoreceptor-mediated phasic and tonic activity in rat portal vein in vitro.
Topics: Animals; Brimonidine Tartrate; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Portal Vein; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Alpha 2-adrenoceptor-mediated vasoconstriction requires a tyrosine kinase.
Topics: Animals; Aorta; Brimonidine Tartrate; Cinnamates; Dose-Response Relationship, Drug; Genistein; Hydroquinones; Isoflavones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Protein-Tyrosine Kinases; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Saphenous Vein; Vasoconstriction | 1995 |
Adrenergic receptor-mediated Cl- transport in rabbit corneal endothelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetazolamide; Adrenergic Agonists; Adrenergic Antagonists; Affinity Labels; Animals; Brimonidine Tartrate; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorescent Dyes; Ion Transport; Isoproterenol; Microscopy, Fluorescence; Norepinephrine; Phentolamine; Phenylephrine; Photometry; Quinolines; Quinoxalines; Rabbits; Receptors, Adrenergic; Yohimbine | 1995 |
Stimulation of oxytocin release in the lactating rat by a central interaction of alpha 1-adrenergic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-sensitive excitatory amino acid mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Drug Synergism; Female; Lactation; Oxytocin; Phenylephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Supraoptic Nucleus | 1993 |
Chloroethylclonidine irreversibly activates postjunctional alpha 2-adrenoceptors in the dog saphenous vein.
Topics: Adrenergic alpha-Agonists; Alkylating Agents; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Saphenous Vein | 1993 |
Nitric oxide modulates sympathetic vasoconstriction and basal blood flow in normal and acutely inflamed rabbit knee joints.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arthritis; Blood Pressure; Brimonidine Tartrate; Clonidine; Electric Stimulation; Infusions, Intra-Arterial; Knee Joint; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Quinoxalines; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1993 |
ANG II reverses selective inhibition of alpha 2-adrenoceptor sensitivity after in vitro isolation of arterioles.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arterioles; Brimonidine Tartrate; Histological Techniques; In Vitro Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Noradrenaline decreases transmission of NMDA- and non-NMDA-receptor mediated monosynaptic EPSPs in rat prefrontal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Antagonists; Afferent Pathways; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Methoxamine; Neurons; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Prefrontal Cortex; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
ATP-sensitive K+ channels mediate alpha 2D-adrenergic receptor contraction of arteriolar smooth muscle and reversal of contraction by hypoxia.
Topics: Adenosine Triphosphate; Animals; Brimonidine Tartrate; Cell Hypoxia; Clonidine; Glyburide; In Vitro Techniques; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1995 |
Effects of wortmannin on alpha-1/alpha-2 adrenergic receptor-mediated contractile responses in rabbit vascular tissues.
Topics: Androstadienes; Animals; Aorta, Thoracic; Brimonidine Tartrate; Calcium; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Saphenous Vein; Wortmannin | 1994 |
Influences of the endothelium and hypoxia on alpha 1- and alpha 2-adrenoceptor-mediated responses in the rabbit isolated pulmonary artery.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Oxygen; Phenylephrine; Pulmonary Artery; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction | 1993 |
Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Bucladesine; Colforsin; Dopamine; Hydrogen; In Vitro Techniques; Kidney Tubules; Levodopa; Phenylephrine; Phorbol 12,13-Dibutyrate; Quinoxalines; Rats; Sodium; Sphingosine | 1993 |
Effects of MPC-1304, a novel Ca2+ entry blocker, on alpha-adrenoceptor-mediated pressor responses in pithed rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Calcium Channel Blockers; Decerebrate State; Dihydropyridines; Electric Stimulation; Nifedipine; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Spinal Cord; Sympathetic Nervous System | 1993 |
Comparative adrenocholinergic control of intracellular Ca2+ in the layers of the ciliary body epithelium.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Ciliary Body; Drug Combinations; Epinephrine; Epithelium; Female; Fluorescent Dyes; Fura-2; Male; Phenylephrine; Pigment Epithelium of Eye; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 1996 |
Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro.
Topics: Acetylcholine; Adrenergic Agonists; Adrenergic Antagonists; Animals; Atropine; Brimonidine Tartrate; Calcium Channel Blockers; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Horses; Isoproterenol; Jejunum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Quinoxalines; Sympathetic Nervous System; Tetrodotoxin; Verapamil; Yohimbine | 1996 |
The actions of medetomidine may not be mediated exclusively by alpha 2-adrenoceptors in the equine saphenous vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Female; Horses; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Structure-Activity Relationship | 1996 |
Differential responses of lateral and ventrolateral rat periaqueductal grey neurones to noradrenaline in vitro.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Calcium; Cell Membrane; Electrophysiology; Lysine; Magnesium; Membrane Potentials; Neurons; Norepinephrine; Patch-Clamp Techniques; Periaqueductal Gray; Phenylephrine; Potassium; Quinoxalines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 1996 |
Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation.
Topics: Animals; Aorta; COS Cells; Cyclic GMP; Guanosine Triphosphate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroso Compounds; Oxadiazoles; Oxidation-Reduction; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
The effect of the vasodilator nicotinamide on cyclic nucleotide pathways in vascular smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arteries; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Imines; In Vitro Techniques; Muscle, Smooth, Vascular; Niacinamide; Oxadiazoles; Phenylephrine; Phosphoric Diester Hydrolases; Quinoxalines; Rats; Rats, Wistar; Second Messenger Systems; Vasodilation; Vasodilator Agents | 1997 |
Nitric oxide inhibition simulates the enhancement of alpha 1 agonist-induced vasoconstriction in diabetes.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1997 |
Alpha-adrenoceptors in equine digital veins: evidence for the presence of both alpha1 and alpha2-receptors mediating vasoconstriction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dopamine; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Veins; Yohimbine | 1997 |
Proliferation of adult rat hepatocytes by hepatocyte growth factor is potentiated by both phenylephrine and metaproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cell Division; Cells, Cultured; Cyclic AMP; Dexamethasone; DNA; Dose-Response Relationship, Drug; Drug Synergism; Hepatocyte Growth Factor; Isoquinolines; Liver; Male; Metaproterenol; Phenylephrine; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Sulfonamides | 1997 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Consciousness; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; N-Methylaspartate; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1997 |
Nonneuronal dopamine.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Benserazide; Biological Transport; Brimonidine Tartrate; Catechol O-Methyltransferase; Dopamine; Kidney; Kidney Cortex; Kidney Tubules; Levodopa; Models, Biological; Monoamine Oxidase; Phenylephrine; Quinoxalines; Sodium-Hydrogen Exchangers | 1998 |
Increased vascular responsiveness to alpha 2-adrenergic stimulation during NOS inhibition-induced hypertension.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Brimonidine Tartrate; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Systole; Vasoconstriction; Yohimbine | 1997 |
The expression of functional postsynaptic alpha2-adrenoceptors in the corpus cavernosum smooth muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Cyclic AMP; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Penis; Phenylephrine; Prazosin; Quinoxalines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Synapses; Tritium; Yohimbine | 1998 |
Alpha-adrenoceptor subtypes of dog saphenous vein: another unusual property.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Dogs; Female; Fluorescence; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Saphenous Vein; Signal Transduction; Yohimbine | 1998 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Phosphodiesterase inhibitors suppress alpha2-adrenoceptor-mediated 5-hydroxytryptamine release from tracheae of newborn rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Enzyme Inhibitors; Epithelium; Female; Male; Oxadiazoles; Phenylephrine; Phosphodiesterase Inhibitors; Quinoxalines; Rabbits; Receptors, Adrenergic, beta-2; Serotonin; Trachea | 1998 |
Effects of insulin-like growth factor I and II on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Topics: Animals; Brimonidine Tartrate; Cell Count; Cell Division; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Drug Interactions; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Isoquinolines; Liver; Male; Metaproterenol; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia.
Topics: Animals; Aorta, Thoracic; Arsenites; Carbon Monoxide; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Hypoxia; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroarginine; Oxadiazoles; Penicillamine; Phenylephrine; Protoporphyrins; Quinoxalines; Rats; Rats, Sprague-Dawley; Reference Values; S-Nitroso-N-Acetylpenicillamine; Sodium Compounds | 1998 |
Inhibition by midazolam of the adrenergic function in the isolated canine mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Animals; Anti-Anxiety Agents; Brimonidine Tartrate; Calcium; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Female; Male; Mesenteric Veins; Midazolam; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha; Tetrodotoxin; Vasoconstrictor Agents; Vasodilator Agents; Yohimbine | 1998 |
Functional characterisation of the pharmacological profile of the putative alpha1B-adrenoceptor antagonist, (+)-cyclazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Spleen; Vasoconstrictor Agents | 1998 |
Insights into the unusual alpha adrenoceptor subtype in dog saphenous vein using phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Phenoxybenzamine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1999 |
Uninjured C-fiber nociceptors develop spontaneous activity and alpha-adrenergic sensitivity following L6 spinal nerve ligation in monkey.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Dose-Response Relationship, Drug; Epidermis; Foot; In Vitro Techniques; Ligation; Lumbosacral Region; Macaca fascicularis; Nerve Fibers; Nociceptors; Peroneal Nerve; Phenylephrine; Quinoxalines; Sensory Thresholds; Spinal Nerves | 1999 |
Importance of agonists in alpha-adrenoceptor classification and localisation of alpha1-adrenoceptors in human prostate.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Brimonidine Tartrate; Calcium; Carotid Artery, Common; Cells, Cultured; Fibroblasts; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prazosin; Prostate; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Saphenous Vein | 1999 |
Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by alpha- and beta-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Brimonidine Tartrate; Cell Division; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Drug Interactions; ErbB Receptors; Isoquinolines; Liver; Male; Metaproterenol; Mitogen-Activated Protein Kinase Kinases; Phenylephrine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinases; Quinoxalines; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases | 1999 |
Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.
Topics: Adrenergic Antagonists; Anesthesia; Aniline Compounds; Animals; Blood Pressure; Brimonidine Tartrate; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Femoral Artery; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Perfusion; Phenylephrine; Piperidines; Prazosin; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilator Agents; Yohimbine | 1999 |
Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Body Temperature Regulation; Brimonidine Tartrate; Cold Temperature; COS Cells; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Microcirculation; Muscle, Smooth, Vascular; Organ Culture Techniques; Phenylephrine; Piperazines; Quinolizines; Quinoxalines; Raynaud Disease; Receptors, Adrenergic, alpha-2; Scleroderma, Systemic; Skin; Tail; Vasoconstriction | 2000 |
Mechanisms of nitric oxide-independent relaxations induced by carbachol and acetylcholine in rat isolated renal arteries.
Topics: Acetylcholine; Animals; Carbachol; Charybdotoxin; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indomethacin; Male; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Oxadiazoles; Peptides; Phenylephrine; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Artery; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2000 |
Increased alpha2-adrenergic constriction of isolated arterioles in diffuse scleroderma.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Arterioles; Brimonidine Tartrate; Female; Humans; Male; Middle Aged; Phenylephrine; Quinoxalines; Scleroderma, Systemic; Vasoconstriction; Vasodilator Agents | 2000 |
Novel S-nitrosothiols do not engender vascular tolerance and remain effective in glyceryl trinitrate-tolerant rat femoral arteries.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Femoral Artery; Glucosamine; Glutathione; Hemoglobins; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroglycerin; Nitroso Compounds; Oxadiazoles; Penicillamine; Perfusion; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effect of norepinephrine receptors on trigeminal rhythm generation in newborn rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Brimonidine Tartrate; Idazoxan; Mastication; Motor Neurons; N-Methylaspartate; Neural Pathways; Norepinephrine; Organ Culture Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Trigeminal Nuclei | 2000 |
Novel S-nitrosothiols do not engender vascular tolerance and remain effective in glyceryltrinitrate-tolerant rat femoral arteries.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Femoral Artery; Glucosamine; Glutathione; Guanylate Cyclase; In Vitro Techniques; Male; Methemoglobin; Nitric Oxide Donors; Nitroglycerin; Nitroso Compounds; Oxadiazoles; Penicillamine; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasoconstrictor Agents; Vasodilation | 2000 |
Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Papaverine; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Pyridines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetrodotoxin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Regulation of ERK phosphorylation in differentiated arterial muscle of rabbits.
Topics: Animals; Arteries; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Histological Techniques; In Vitro Techniques; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Osmolar Concentration; Oxadiazoles; Phenylephrine; Phosphorylation; Quinoxalines; Rabbits; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2001 |
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 2001 |
The relaxation induced by S-nitroso-glutathione and S-nitroso-N-acetylcysteine in rat aorta is not related to nitric oxide production.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Oxadiazoles; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Ryanodine; S-Nitrosoglutathione; Thapsigargin; Vasoconstrictor Agents; Vasodilation | 2001 |
The effect of adrenergic compounds on neurogenic dural vasodilatation.
Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Dose-Response Relationship, Drug; Dura Mater; Electric Stimulation; Injections, Intravenous; Male; Phenylephrine; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation; Yohimbine | 2001 |
Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicorandil; Nitroprusside; Oxadiazoles; Penis; Phenylephrine; Potassium Channels; Quinoxalines; Rabbits; Vasodilator Agents | 2001 |
High-salt diet enhances vascular reactivity in pregnant rats with normal and reduced uterine perfusion pressure.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Nitroprusside; Oxadiazoles; Phenylephrine; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Uterus; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine | 2001 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine | 2001 |
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats.
Topics: Acetylcholine; Animals; Antineoplastic Agents; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Phenylephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Quinoxalines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Binding, Competitive; Brimonidine Tartrate; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Idazoxan; Middle Cerebral Artery; Norepinephrine; Phenylephrine; Pregnancy; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2002 |
Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Endotoxemia; Enzyme Activation; Hemorrhage; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuroimmunomodulation; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phentolamine; Phenylephrine; Phosphorylation; Propranolol; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Quinoxalines; Respiratory Distress Syndrome; Ribosomal Protein S6 Kinases | 2002 |
Different contractile effects of alpha1- and alpha2-adrenergic agonists on horse isolated common digital artery smooth muscle ring preparations in vitro.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Calcium; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endothelin Receptor Antagonists; Endothelium, Vascular; Horses; Imidazoles; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Quinoxalines | 2002 |
Vasocontractile effects of alpha 2-adrenergic agonists associated with intracellular calcium release.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Calcium; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxymetazoline; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction | 2002 |
YC-1 potentiates the nitric oxide/cyclic GMP pathway in corpus cavernosum and facilitates penile erection in rats.
Topics: Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indazoles; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroprusside; Oxadiazoles; Penile Erection; Penis; Phenylephrine; Quinoxalines; Rabbits; Rats; Rats, Wistar; Signal Transduction; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Estrogen-induced autonomic effects are mediated by NMDA and GABAA receptors in the parabrachial nucleus.
Topics: Animals; Autonomic Nervous System; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Antagonists; Fulvestrant; GABA Antagonists; Heart Rate; Male; Membrane Potentials; Phenylephrine; Piperazines; Pons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Abnormal activation of Na+-K+ pump in aortas from rats with endotoxaemia.
Topics: Animals; Aorta, Thoracic; Endotoxemia; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Ouabain; Oxadiazoles; Phenylephrine; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Time Factors | 2003 |
Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Drug Antagonism; Drug Synergism; Guanylate Cyclase; Male; Mesenteric Arteries; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle Relaxation; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Phenylephrine; Polysaccharides; Quinoxalines; Receptors, Atrial Natriuretic Factor; Signal Transduction; Spermine | 2003 |
Enhancement of endotoxin-induced vascular hyporeactivity to phenylephrine in the thoracic aortas of Mg-deficient rats ex vivo.
Topics: Amidines; Animals; Aorta, Thoracic; Benzylamines; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; Injections, Intraperitoneal; Interleukin-1; Lipopolysaccharides; Magnesium Deficiency; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Evidence for the mechanisms underlying the effects of pimaradienoic acid isolated from the roots of Viguiera arenaria on rat aorta.
Topics: Animals; Aorta, Thoracic; Asteraceae; Brazil; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Oxadiazoles; Phenylephrine; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasodilation | 2004 |
Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.
Topics: Adolescent; Adult; Child; Cyclic GMP; Drug Evaluation, Preclinical; Electric Stimulation; Enzyme Inhibitors; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penis; Phenylephrine; Piperazines; Priapism; Purines; Quinoxalines; Scorpion Venoms; Second Messenger Systems; Sildenafil Citrate; Sodium Channel Blockers; Sulfones; Tetrodotoxin | 2004 |
Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Pituitary-Adrenal System; Quinoxalines; Radioimmunoassay; Rats; Serotonin; Serotonin Receptor Agonists; Valine | 2004 |
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Female; Interleukin-6; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Phenylephrine; Pregnancy; Pregnancy, Animal; Progesterone; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2004 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma.
Topics: Adult; Animals; Ascorbic Acid; Copper; Female; Humans; Mesenteric Arteries; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxidative Stress; Phenylephrine; Pre-Eclampsia; Pregnancy; Quinoxalines; Serum Albumin, Bovine; Vasodilation | 2005 |
Endothelial mechanisms underlying responses to acetylcholine in the horse deep dorsal penile vein.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Calcium; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Horses; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Penis; Phenylephrine; Potassium; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Sodium Nitrite; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins | 2005 |
Peroxynitrite-induced relaxation in isolated rat aortic rings and mechanisms of action.
Topics: Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; In Vitro Techniques; Male; Marine Toxins; Methylene Blue; Oxadiazoles; Oxazoles; Peroxynitrous Acid; Phenylephrine; Piperazines; Potassium; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2005 |
Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery.
Topics: Amides; Animals; Blotting, Western; Celiac Artery; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Guanine Nucleotide Exchange Factors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phenylephrine; Potassium; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Dual actions of dephostatin on the nitric oxide/cGMP-signalling pathway in porcine iliac arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydroquinones; Iliac Artery; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Phenylephrine; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Quinoxalines; Serine; Signal Transduction; Swine; Triazoles; Tyrosine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
alpha1-Adrenergic modulation of synaptic input to Purkinje neurons in rat cerebellar brain slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Animals, Newborn; Cerebellum; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Norepinephrine; Patch-Clamp Techniques; Phentolamine; Phenylephrine; Picrotoxin; Prazosin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Synapses; Tetrodotoxin; Time Factors | 2005 |
Knockdown of arginase I restores NO signaling in the vasculature of old rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Arginase; Arginine; Calcium; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Analysis of the mechanisms underlying the vasorelaxant action of angiotensin II in the isolated rat carotid.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peptide Fragments; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Saralasin; Vasoconstrictor Agents; Vasodilation | 2006 |
Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Brimonidine Tartrate; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methoxamine; Nitric Oxide; Phenylephrine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin; Vasoconstrictor Agents; Vasodilation; Yohimbine | 2006 |
Modulation of gap-junction-dependent arterial relaxation by ascorbic acid.
Topics: Animals; Ascorbic Acid; Boron Compounds; Connexin 43; Connexins; Dose-Response Relationship, Drug; Endothelium, Vascular; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Gap Junctions; Hydrazines; Iliac Artery; Indoles; Indomethacin; Male; Membrane Potentials; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rabbits; Vasodilation | 2007 |
Investigation of the vasorelaxant effects of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) and diethylamine/nitric oxide (DEA/NO) on the human radial artery used as coronary bypass graft.
Topics: Aged; Analysis of Variance; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Female; Humans; Hydrazines; In Vitro Techniques; Indazoles; Male; Middle Aged; Nitric Oxide Donors; Oxadiazoles; Peptides; Phenylephrine; Potassium Channels, Calcium-Activated; Quinoxalines; Radial Artery; Vasoconstrictor Agents; Vasodilation | 2007 |
Sulphonylureas induced vasorelaxation of mouse arteries.
Topics: Adamantane; Animals; Arteries; Endothelium, Vascular; Glyburide; In Vitro Techniques; KATP Channels; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Morpholines; Muscle Relaxation; Muscle, Smooth, Vascular; Oxadiazoles; Phenylephrine; Potassium Channel Blockers; Quinoxalines; Sulfonylurea Compounds; Vascular Resistance; Vasoconstrictor Agents | 2007 |
The role of NMDA and non-NMDA receptors in the NTS in mediating three distinct sympathoinhibitory reflexes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Blood Pressure; Cholecystokinin; GABA Agonists; Heart Rate; Kynurenic Acid; Male; Muscimol; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Synaptic Transmission | 2007 |
Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Autonomic Denervation; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Oxyhemoglobins; Phenylephrine; Quinoxalines; Rats | 2007 |
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
Topics: Aminoquinolines; Animals; Carotid Artery, Internal; Catalase; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Free Radical Scavengers; Guanylate Cyclase; Humans; Hydrogen Peroxide; Hydroquinones; In Vitro Techniques; Indomethacin; Mannitol; Mesenteric Artery, Superior; Methylene Blue; Muramidase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Phenylephrine; Prostaglandins; Protein Kinase Inhibitors; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sepsis; Signal Transduction; Soluble Guanylyl Cyclase; Thionucleotides; Time Factors; Vasoconstrictor Agents; Vasodilation | 2008 |
Inhibition by lithium of the nitrergic relaxation of rat anococcygeus muscle.
Topics: Analysis of Variance; Animals; Arginine; Electric Stimulation; Lithium Chloride; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
N-acetylcysteine-induced vasodilation involves voltage-gated potassium channels in rat aorta.
Topics: Acetylcysteine; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanylate Cyclase; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxadiazoles; Phenylephrine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vasoconstrictor Agents; Vasodilation | 2009 |
Temporal evolution of intraocular pressure elevation after pupillary dilation in pigment dispersion syndrome.
Topics: Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Exfoliation Syndrome; Humans; Intraocular Pressure; Male; Middle Aged; Mydriatics; Ocular Hypertension; Phenylephrine; Pupil; Quinoxalines; Retrospective Studies; Tonometry, Ocular; Tropicamide | 2009 |
Endothelium-derived nitric oxide contributes to the vasorelaxant response induced by mesoionic 2-(4-chlorophenyl)-3-methyl-4-(4-methoxyphenyl)-1;3-thiazolium-5-thyolate (CMMTT) in rats.
Topics: Animals; Biological Factors; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Thiazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Differential involvement of alpha1-adrenoceptors in vasoconstrictor responses to cooling in mouse plantar arteries in vitro and in vivo.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Cold Temperature; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle, Smooth, Vascular; Phentolamine; Phenylephrine; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Skin; Tetrodotoxin; Vasoconstriction | 2009 |
Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzophenanthridines; Body Weight; Calcium; Chick Embryo; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Femoral Artery; Hypoxia; NG-Nitroarginine Methyl Ester; Oxadiazoles; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Quinoxalines; rho-Associated Kinases; Vasoconstriction | 2010 |
Comparison of vasorelaxant effect and tolerance profile of a novel isosorbide-5-mononitrate derivative with its stereoisomer and parent drug on rat mesenteric artery.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Electrophoresis, Capillary; Endothelium, Vascular; In Vitro Techniques; Isosorbide Dinitrate; Magnetic Resonance Spectroscopy; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Spectrophotometry, Infrared; Stereoisomerism; Vasoconstrictor Agents; Vasodilator Agents | 2010 |
Effects induced by inhibitors of the phosphatidylinositol 3-kinase/Akt and nitric oxide synthase/guanylyl cyclase pathways on the isometric contraction in rat aorta: a comparative study.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Chromones; Endothelium, Vascular; Guanylate Cyclase; Isometric Contraction; Male; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Phenylephrine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Potassium; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin | 2011 |
Regional heterogeneity of α-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Arterioles; Brimonidine Tartrate; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle, Skeletal; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2010 |
Ruthenium-nitrite complex as pro-drug releases NO in a tissue and enzyme-dependent way.
Topics: Animals; Aorta, Thoracic; Guanylate Cyclase; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phenylephrine; Phosphoric Diester Hydrolases; Prodrugs; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ruthenium Compounds; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2011 |
Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases?
Topics: Animals; Aorta, Thoracic; Brain; Cinnamates; Drug Design; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Propanols; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Activation of extracellular-signal regulated kinase by platelet-derived growth factor is potentiated by phenylephrine in primary cultures of adult rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Brimonidine Tartrate; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Male; Metaproterenol; Phenylephrine; Phosphorylation; Platelet-Derived Growth Factor; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2011 |
The role of capillarisin from Artemisia capillaris on penile erection.
Topics: Animals; Artemisia; Chromones; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Evaluation, Preclinical; Ethanol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Phenylephrine; Phosphodiesterase 5 Inhibitors; Plant Extracts; Quinoxalines; Rabbits; Radioimmunoassay; Signal Transduction | 2012 |
Strabismus surgery hemostasis.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Blood Loss, Surgical; Brimonidine Tartrate; Case-Control Studies; Female; Hemostasis, Surgical; Humans; Male; Oculomotor Muscles; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Phenylephrine; Postoperative Hemorrhage; Prospective Studies; Quinoxalines; Strabismus; Treatment Outcome; Vasoconstrictor Agents | 2012 |
The effect of first-in-class small molecule RhoA inhibitor, HL07, on the phenylephrine-induced artery contraction.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Cinnamates; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Male; Myocytes, Smooth Muscle; Nifedipine; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA, Messenger; Thapsigargin; Vasoconstriction; Vasoconstrictor Agents | 2012 |
The 2-nitrate-1,3-dibuthoxypropan, a new nitric oxide donor, induces vasorelaxation in mesenteric arteries of the rat.
Topics: Animals; Free Radical Scavengers; Glycerol; Guanylate Cyclase; In Vitro Techniques; Intracellular Space; Male; Mesenteric Arteries; Myocytes, Smooth Muscle; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Propane; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasoconstriction; Vasodilation; Vasodilator Agents | 2012 |
[Peripheral mechanisms of action of oxatriazolium-5-olate derivative 3-(3-[1,2,4]-triazolo)oxatriazolium-5-olate in spontaneously hypertensive rats].
Topics: Animals; Arteries; Guanylate Cyclase; Heme; Male; Nitric Oxide; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Wistar; Tail; Tissue Culture Techniques; Triazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2012 |
Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phenylephrine; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Propanols; Quinoxalines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilation | 2012 |
Contribution of α-adrenoceptor stimulation by phenylephrine to basal nitric oxide production in the isolated mouse aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Yohimbine | 2013 |
The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta.
Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Lignans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Piper; Quinoxalines; Rats; Rats, Wistar; Vasodilation | 2013 |
2-Aryl- and 2-amido-benzothiazoles as multifunctional vasodilators on rat artery preparations.
Topics: Animals; Arteries; Benzothiazoles; Calcium; Cyclic GMP; Extracellular Space; In Vitro Techniques; Intracellular Space; Male; Muscle Cells; Nitroprusside; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasodilation; Vasodilator Agents | 2013 |
Endothelium- and smooth muscle-dependent vasodilator effects of Citrus aurantium L. var. amara: Focus on Ca(2+) modulation.
Topics: Animals; Aorta; Calcium; Citrus; Dinoprost; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Space; Isometric Contraction; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Oils, Volatile; Oxadiazoles; Phenylephrine; Quinoxalines; Ryanodine Receptor Calcium Release Channel; Vasodilation; Vasodilator Agents | 2016 |
Role of Carbon Monoxide in the Mechanisms of Action of Extracellular ATP on Contractile Activity of Vascular Smooth Muscle Cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Carbon Monoxide; Cells, Cultured; Endothelium; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Organometallic Compounds; Oxadiazoles; Phenylephrine; Protoporphyrins; Purinergic P2X Receptor Agonists; Purinergic P2Y Receptor Agonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P2X; Receptors, Purinergic P2Y | 2019 |
Both α
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Thymine; Yohimbine | 2021 |
Synthesis and vasorelaxant evaluation of novel 7-methoxyl-2,3-disubstituted-quinoxaline derivatives.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Phenylephrine; Quinoxalines; Structure-Activity Relationship; Vasodilator Agents | 2021 |