Page last updated: 2024-08-17

quinoxalines and pentylenetetrazole

quinoxalines has been researched along with pentylenetetrazole in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (38.89)18.2507
2000's5 (27.78)29.6817
2010's5 (27.78)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Benjamin, D; Lal, H; Meyerson, LR1
Kubová, H; Mares, P; Vachová, D; Velísek, L1
Donevan, SD; Rogawski, MA; Yamaguchi, S1
Hönack, D; Löscher, W1
Belonga, KL; Carter, DB; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; TenBrink, RE; VonVoigtlander, PF1
Belonga, KL; Carter, DB; Im, WB; Jacobsen, EJ; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; VonVoigtlander, PF1
Belonga, KL; Carter, DB; Im, HK; Im, WB; Jacobsen, EJ; Mickelson, JW; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; TenBrink, RE; VonVoigtlander, PF; Zhong, WZ1
Bell-Horner, CL; Das, P; Dillon, GH; Machu, TK1
Huang, YG; Jiang, W; Wolfe, K; Xiao, L; Zhang, X; Zhang, ZJ1
Gerardy-Schahn, R; Pekcec, A; Potschka, H; Weinhold, B1
Itoh, K; Watanabe, M1
Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA1
Hamann, M; Kreil, A; Richter, A; Sander, SE1
Gutiérrez, R; Treviño, M; Vivar, C1
Ayyad, RR; Elhelby, AA; Zayed, MF1
Gmiro, VE; Serdyuk, SE; Veselkina, OS1
Chen, W; Gao, J; Li, XH; Li, YS; Lin, XY1
Abulkhair, HS; Ahmed, HEA; Akl, EN; Bayoumi, AH; El-Adl, K; El-Morsy, A; El-Zoghbi, MS; Elmeligie, S; Ghiaty, A; Hassan, MH; Zayed, MF1

Other Studies

18 other study(ies) available for quinoxalines and pentylenetetrazole

ArticleYear
The effects of 5-HT1B characterizing agents in the mouse elevated plus-maze.
    Life sciences, 1990, Volume: 47, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Male; Mice; Mice, Inbred Strains; Models, Psychological; Pentylenetetrazole; Piperazines; Quinoxalines; Serotonin

1990
Kainate/AMPA receptor antagonists are anticonvulsant against the tonic hindlimb component of pentylenetetrazol-induced seizures in developing rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Anticonvulsants; Behavior, Animal; Epilepsy, Tonic-Clonic; Hindlimb; Male; Muscle Tonus; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Synaptic Transmission

1995
Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models.
    Epilepsy research, 1993, Volume: 15, Issue:3

    Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Kainic Acid; Male; Mice; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures

1993
Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Flumazenil; Male; Mice; Muscle Relaxants, Central; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Reflex; Seizures; Synaptic Transmission

1994
High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; GABA Agonists; GABA Antagonists; Molecular Conformation; Molecular Structure; Oxadiazoles; Pentylenetetrazole; Quinoxalines; Rats; Receptors, GABA-A

1996
3-Phenyl-substituted imidazo[1,5-alpha]quinoxalin-4-ones and imidazo[1,5-alpha]quinoxaline ureas that have high affinity at the GABAA/benzodiazepine receptor complex.
    Journal of medicinal chemistry, 1996, Sep-13, Volume: 39, Issue:19

    Topics: Animals; Anticonvulsants; Benzodiazepines; Cell Membrane; Cerebral Cortex; Drug Synergism; Ethanol; Imidazoles; Ligands; Male; Mice; Molecular Conformation; Molecular Structure; Pentylenetetrazole; Quinoxalines; Rats; Receptors, GABA; Seizures; Structure-Activity Relationship; Substance-Related Disorders

1996
Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Biological Availability; Cell Line; Cerebellum; Convulsants; Cyclic GMP; Drug Evaluation, Preclinical; GABA Agonists; Imidazoles; In Vitro Techniques; Ligands; Male; Mice; Models, Molecular; Molecular Conformation; Pentylenetetrazole; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Urea

1999
The GABA(A) receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors.
    Neuropharmacology, 2003, Volume: 44, Issue:4

    Topics: Animals; Cell Line; GABA Antagonists; GABA-A Receptor Antagonists; Humans; Ligands; Mice; Pentylenetetrazole; Picrotoxin; Quinoxalines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists

2003
Ionotropic glutamate receptor antagonists inhibit the proliferation of granule cell precursors in the adult brain after seizures induced by pentylenetrazol.
    Brain research, 2004, Sep-10, Volume: 1020, Issue:1-2

    Topics: Animals; Cell Count; Cell Proliferation; Dentate Gyrus; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Male; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Seizures; Stem Cells

2004
Deficiency of neural cell adhesion molecule or its polysialylation modulates pharmacological effects of the AMPA receptor antagonist NBQX.
    Neuroscience, 2008, Apr-09, Volume: 152, Issue:4

    Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Cell Adhesion Molecules; Pentylenetetrazole; Quinoxalines; Seizures; Sialyltransferases

2008
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase.
    Neuroscience, 2009, Mar-17, Volume: 159, Issue:2

    Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures

2009
Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.
    Brain research bulletin, 2009, Jun-30, Volume: 79, Issue:5

    Topics: Animals; Anticonvulsants; Antioxidants; Brain; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Organoselenium Compounds; Pentylenetetrazole; Pilocarpine; Quinoxalines; Rats; Rats, Wistar; Seizures; Time Factors; Treatment Outcome

2009
Effects of pharmacological entopeduncular manipulations on idiopathic dystonia in the dt(sz) mutant hamster.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:6

    Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine

2010
Excitation-inhibition balance in the CA3 network--neuronal specificity and activity-dependent plasticity.
    The European journal of neuroscience, 2011, Volume: 33, Issue:10

    Topics: Animals; CA3 Region, Hippocampal; Convulsants; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Kindling, Neurologic; Male; Nerve Net; Neuronal Plasticity; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Seizures; Synaptic Transmission; Valine

2011
Synthesis and biological evaluation of some novel quinoxaline derivatives as anticonvulsant agents.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:7

    Topics: Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Pentylenetetrazole; Phenobarbital; Quinoxalines; Seizures; Structure-Activity Relationship

2011
Combined blockade of NMDA and AMPA receptors prevents acute kainate seizures and chronic kainate lethality in rats.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:1

    Topics: Adamantane; Amines; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intramuscular; Kainic Acid; Male; Memantine; N-Methylaspartate; Neuroprotective Agents; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Analysis

2014
AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Aggrecans; Animals; Anticonvulsants; Behavior, Animal; Chondroitin ABC Lyase; Disease Models, Animal; Down-Regulation; Epilepsy; Immunohistochemistry; Male; Neurocan; Pentylenetetrazole; Peripheral Nerves; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tenascin

2016
In vivo- and in silico-driven identification of novel synthetic quinoxalines as anticonvulsants and AMPA inhibitors.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Molecular Docking Simulation; Molecular Structure; Pentylenetetrazole; Quinoxalines; Seizures; Structure-Activity Relationship

2021