quinoxalines has been researched along with organophosphonates in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 12 (60.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P | 1 |
| Dirnagl, U; Huth, A; Jacobsen, P; McDonald, F; Neuhaus, R; Ottow, E; Schneider, HH; Sheardown, M; Turski, L; Wiegand, F | 1 |
| Acklin, P; Auberson, YP; Bischoff, S; Moretti, R; Ofner, S; Schmutz, M; Veenstra, SJ | 1 |
| Groom, A; Smith, T; Turski, L; Zhu, B | 1 |
| Ametamey, SM; Auberson, YP; Bischoff, S; Bläuenstein, P; Carrey-Rémy, N; Kokic, M; Schmutz, M; Schubiger, PA; Willmann, M | 1 |
| Kapousta-Bruneau, NV | 1 |
| De Keyser, J; Diener, HC; Elting, JW; Hommel, M; Kaste, M; Lees, KR; Sulter, GA; Teelken, AW; Versavel, M | 1 |
| Egebjerg, J; Gouaux, E; Greenwood, JR; Hogner, A; Kastrup, JS; Larsen, IK; Liljefors, T; Lunn, ML | 1 |
| Cebere, A; Cebers, G; Kosowski, AR; Liljequist, S; Swanhagen, AC | 1 |
| Albrecht, J; Hilgier, W; Oja, SS; Saransaari, P | 1 |
| De Keyser, J; Diener, HC; Hommel, M; Kaste, M; Lees, KR; Steiner, H; Versavel, M; Walters, MR | 1 |
| Herreras, O; Larrosa, B; López-Aguado, L; Pastor, J | 1 |
| Gronier, B | 1 |
| Bauer, I; Freynhagen, R; Hermanns, H; Kollosche, K; Lipfert, P; Muth-Selbach, U; Stegmann, JU | 1 |
| Abe, K; Chou, DY; Janssen, MJ; Partridge, JG; Vicini, S; Zukowska, Z | 1 |
| Bergholz, R; Rüther, K; Staks, T | 1 |
| Dehmel, M; Fischer, C; Henle, F; Leemhuis, J; Meyer, DK | 1 |
| Ikemoto, S; Jhou, TC; Shin, R; Vollrath-Smith, FR; Webb, SM; Xu, S | 1 |
| Li, M; Sobolevsky, AI; Yelshanskaya, MV | 1 |
| Boesen, T; Dorosz, J; Gajhede, M; Kastrup, JS; Krintel, C; Larsen, AH; Mirza, O; Thorsen, TS; Venskutonytė, R | 1 |
3 trial(s) available for quinoxalines and organophosphonates
| Article | Year |
|---|---|
AMPA antagonist ZK200775 in patients with acute ischemic stroke: possible glial cell toxicity detected by monitoring of S-100B serum levels.
Topics: Acute Disease; Aged; Area Under Curve; Biomarkers; Brain Ischemia; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Nerve Growth Factors; Neuroglia; Organophosphonates; Phosphopyruvate Hydratase; Quinoxalines; Receptors, AMPA; Regression Analysis; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Severity of Illness Index; Stroke; Treatment Outcome | 2002 |
The AMPA antagonist ZK 200775 in patients with acute ischaemic stroke: a double-blind, multicentre, placebo-controlled safety and tolerability study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; Electrocardiography; Humans; Middle Aged; Organophosphonates; Patient Compliance; Quinoxalines; Receptors, AMPA; Stroke; Treatment Outcome | 2005 |
Effects of the AMPA antagonist ZK 200775 on visual function: a randomized controlled trial.
Topics: Aged; Color Vision; Darkness; Electroretinography; Evoked Potentials, Visual; Humans; Male; Middle Aged; Organophosphonates; Quinoxalines; Receptors, AMPA; Vision, Ocular; Visual Acuity | 2010 |
17 other study(ies) available for quinoxalines and organophosphonates
| Article | Year |
|---|---|
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus | 1996 |
ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebrovascular Disorders; Craniocerebral Trauma; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; In Vitro Techniques; Mice; Neuroprotective Agents; Organophosphonates; Quinoxalines; Radioligand Assay; Rats | 1998 |
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Animal; Electroshock; Hydrobromic Acid; Hydrochloric Acid; Hydroxy Acids; Inhibitory Concentration 50; Mice; N-Methylaspartate; Organophosphonates; Quinoxalines | 1999 |
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Neurons; Multiple Sclerosis; Muscle Tonus; Myelin Basic Protein; Neurons; Organophosphonates; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; Receptors, Kainic Acid; Recurrence; Spinal Cord; T-Lymphocytes | 2000 |
Synthesis, radiolabelling and biological characterization of (D)-7-iodo-N-(1-phosphonoethyl)-5-aminomethylquinoxaline-2,3-dione, a glycine-binding site antagonist of NMDA receptors.
Topics: Animals; Anticonvulsants; Binding Sites; Female; Glycine; Inhibitory Concentration 50; Iodine Radioisotopes; Kidney; Mice; Mice, Inbred BALB C; Organophosphonates; Quinoxalines; Radioligand Assay; Radiopharmaceuticals; Receptors, N-Methyl-D-Aspartate; Substrate Specificity; Tissue Distribution | 2000 |
Opposite effects of GABA(A) and GABA(C) receptor antagonists on the b-wave of ERG recorded from the isolated rat retina.
Topics: Allylamine; Animals; Bicuculline; Dizocilpine Maleate; Electroretinography; Excitatory Amino Acid Antagonists; GABA Antagonists; Nerve Net; Organophosphonates; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Rod Photoreceptor Cells | 2000 |
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; Isoxazoles; Ligands; Models, Molecular; Organophosphonates; Quinoxalines; Receptors, AMPA | 2003 |
Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dopamine; Male; Microdialysis; Motor Activity; Nicotine; Nucleus Accumbens; Organophosphonates; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Time Factors | 2004 |
A novel glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.
Topics: Allosteric Regulation; Ammonia; Animals; Binding Sites; Corpus Striatum; Cyclic GMP; Glycine; Male; Microdialysis; Microinjections; Neurons; Neurotoxins; Nitric Oxide; Organophosphonates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2004 |
A role for glutamate and glia in the fast network oscillations preceding spreading depression.
Topics: Animals; Cortical Spreading Depression; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluoroacetates; Glutamic Acid; Hippocampus; In Vitro Techniques; Nerve Net; Neuroglia; Neurons; Organophosphonates; Periodicity; Piperazines; Potassium; Quinoxalines; Rats; Time Factors | 2006 |
Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; Glutamic Acid; Male; Neurons; Organophosphonates; Piperazines; Prefrontal Cortex; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Ventral Tegmental Area | 2008 |
Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system.
Topics: Analgesics; Animals; Binding Sites; Glycine; Glycine Agents; Lidocaine; Organophosphonates; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Substrate Specificity; Synaptic Transmission | 2009 |
Excitatory and inhibitory synapses in neuropeptide Y-expressing striatal interneurons.
Topics: Animals; Bicuculline; Biophysical Phenomena; Biophysics; Choline O-Acetyltransferase; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Interneurons; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptide Y; Organophosphonates; Parvalbumins; Patch-Clamp Techniques; Piperazines; Quinoxalines; Sodium Channel Blockers; Synapses; Synaptic Potentials; Tetrodotoxin | 2009 |
Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Topics: Animals; Azabicyclo Compounds; Cells, Cultured; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; HeLa Cells; Hippocampus; Humans; N-Methylaspartate; Neurons; Organophosphonates; Phenols; Piperidines; Protein Subunits; Pseudopodia; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2012 |
Rewarding and incentive motivational effects of excitatory amino acid receptor antagonists into the median raphe and adjacent regions of the rat.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Light; Male; Motivation; Motor Activity; Organophosphonates; Photic Stimulation; Pons; Quinoxalines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration; Time Factors; Vision, Ocular | 2012 |
Structure of an agonist-bound ionotropic glutamate receptor.
Topics: Animals; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Models, Chemical; Organophosphonates; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA | 2014 |
Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Organophosphonates; Protein Binding; Protein Domains; Quinoxalines; Rats; Receptors, AMPA; Recombinant Proteins; Sf9 Cells; Spodoptera | 2021 |