quinoxalines has been researched along with nvp-bsk805 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Baffert, F; Blasco, F; Brueggen, J; Chène, P; De Pover, A; Drueckes, P; Erdmann, D; Furet, P; Gerspacher, M; Hofmann, F; Lang, M; Ledieu, D; Nolan, L; Pissot-Soldermann, C; Radimerski, T; Régnier, CH; Ruetz, S; Tavares, GA; Trappe, J; Vangrevelinghe, E; Wartmann, M; Wyder, L | 1 |
| Andraos, R; Guthy, DA; Qian, Z; Radimerski, T; Rubert, J | 1 |
| Dörken, B; Grille, P; Kaeda, J; le Coutre, P; Manley, PW; Marque, F; Oberender, C; Radimerski, T; Ringel, F; Schwarz, M | 1 |
| Cheon, JH; Kim, HS; Kim, KS; Kim, M; Yadav, DK; Yoon, S | 1 |
| Baur, EM; Gschwend, JE; Hindupur, SV; Holm, PS; Horn, T; Koch, JA; Nawroth, R; Schmid, SC; Slotta-Huspenina, J; Wang, D; Youssef, A | 1 |
| Hou, Q; Hu, Z; Hua, Y; Jiang, Z; Li, Y; Wang, W; Wu, H; Wu, S; Yang, L; Yue, J; Zhang, X; Zheng, X | 1 |
6 other study(ies) available for quinoxalines and nvp-bsk805
| Article | Year |
|---|---|
Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Erythropoiesis; Humans; Janus Kinase 2; K562 Cells; Mice; Mice, Inbred BALB C; Mice, SCID; Models, Molecular; Molecular Structure; Mutation; Phosphorylation; Polycythemia; Protein Structure, Tertiary; Quinoxalines; Rats; Splenomegaly; STAT5 Transcription Factor | 2010 |
Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.
Topics: Amino Acid Substitution; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Blotting, Western; Caspase Inhibitors; Caspases; Cell Line; Cell Line, Tumor; Cell Survival; Flow Cytometry; Humans; Janus Kinase 2; Membrane Proteins; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; RNA Interference; Signal Transduction | 2011 |
Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines.
Topics: Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Janus Kinase 2; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Myeloproliferative Disorders; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Quinoxalines; STAT5 Transcription Factor; Tumor Suppressor Proteins | 2014 |
The JAK2 inhibitors CEP-33779 and NVP-BSK805 have high P-gp inhibitory activity and sensitize drug-resistant cancer cells to vincristine.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Janus Kinase 2; Protein Kinase Inhibitors; Pyridines; Quinoxalines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured; Vincristine | 2017 |
STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Combined Modality Therapy; Cyclic S-Oxides; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Humans; Hydroxybenzoates; Janus Kinases; Nitriles; Nitrofurans; Oncolytic Virotherapy; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Quinoxalines; STAT3 Transcription Factor; STAT6 Transcription Factor; Urinary Bladder Neoplasms | 2020 |
NVP-BSK805, an Inhibitor of JAK2 Kinase, Significantly Enhances the Radiosensitivity of Esophageal Squamous Cell Carcinoma in vitro and in vivo.
Topics: Animals; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Janus Kinase 2; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Protein Kinase Inhibitors; Quinoxalines; Tumor Cells, Cultured | 2020 |