Page last updated: 2024-08-17

quinoxalines and ng-nitroarginine methyl ester

quinoxalines has been researched along with ng-nitroarginine methyl ester in 259 studies

Research

Studies (259)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's41 (15.83)18.2507
2000's163 (62.93)29.6817
2010's53 (20.46)24.3611
2020's2 (0.77)2.80

Authors

AuthorsStudies
Baird, M; Daly, CJ; Gordon, JF; McGrath, JC1
Browne, SE; Bullock, R; Dawson, D; Fujisawa, H; MacKay, KB; McCulloch, J1
Grillner, S; Hökfelt, T; Pieribone, VA; Xu, ZQ; Zhang, X1
Shibata, S; Tanaka, T; Watanabe, S; Yamamoto, Y1
Dyamenahalli, U; Haworth, SG; Stuart-Smith, K; Tulloh, RM1
Albino-Teixeira, A; Guimarães, S; Moura, D; Paiva, MQ; Vaz-da-Silva, MJ1
Ferrell, WR; Najafipour, H1
MacLean, MR; McCulloch, KM; McGrath, JC1
Bryan, RM; Childres, WF; Eichler, MY; Johnson, TD; Suresh, MS; Swafford, MW1
Black, JW; Saxena, PR; Shankley, NP; Van der Graaf, PH1
Balster, RL; Cristello, AF; Wiley, JL1
Hicks, C; O'Neill, MJ; Ward, M1
Dresner, LS; Mueller, CM; Ponomarenko, IN; Wait, RB; Wang, SP; West, MW1
Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Yamada, K1
Ger, LP; Lin, HC; Lo, WC; Tseng, CJ; Tung, CS1
Díaz-Cazorla, M; Jiménez, W; Lamas, S; Pérez-Sala, D; Ros, J1
Morris, R; Thippeswamy, T1
Catalin, D; Miolan, JP; Niel, JP; Quinson, N1
Barbeito, L; Beckman, JS; Cornwell, TL; Estévez, AG; Radi, R; Spear, N; Thompson, JA1
Li, L; Paakkari, I; Vaali, K; Vapaatalo, H1
Doughty, JM; Langton, PD1
de Vente, J; Hopkins, DA; Markerink-van Ittersum, M; Steinbusch, HW1
Bartfai, T; Caltavuturo, C; Consolo, S; Uboldi, MC1
Muneoka, Y; Pedder, SM; Walker, RJ1
Lefebvre, RA1
Chen, SJ; Wu, CC; Yen, MH1
Ruiz, E; Tejerina, T1
Coutinho, VS; Gebhart, FG; Urban, OM1
Fernández-Tomé, P; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA1
Hwang, TL; Teng, CM; Wu, CC1
Cellek, S; Moncada, S1
Aizman, R; Brismar, H; Celsi, G1
Akashi, C; Matsumura, Y; Mitsutomi, N; Odagiri, J1
Bryan, RM; Johnson, TD; Marrelli, SP; Mombouli, JV; You, J1
D'Angelo, S; Mulè, F; Serio, R1
Alfonzo, MJ; González de Alfonzo, R; Guerra de González, L; Lippo de Bécemberg, I; Misle, A; Napoleón de Herrera, V; Pacheco, G1
Duszyk, M; Thethi, K1
Chan, PH; Hirvonen, T; Keinänen, R; Koistinaho, J; Koponen, S; Närhi, M; Roivainen, R1
Budelmann, BU; Tu, Y2
Brown, T; Bunton, D; MacDonald, A; McGrath, JC; Shaw, AM; Tracey, A1
Aguilar, E; González, D1
Ekblad, E1
Aguirre-Bañuelos, P; Granados-Soto, V1
Huh, IH; Lee, YW; Park, JI; Shin, CY; Sohn, UD1
Jonas, M; Mundey, MK; Scholefield, JH; Wilson, VG; Worthley, T1
Brawley, L; MacDonald, A; Shaw, AM1
Duarte, ID; Ferreira, SH1
Kurowski, S; Vemulapalli, S2
Jiang, F; Li, CG; Rand, MJ1
Barrachina, MD; Esplugues, JV; García-Zaragozá, E; Moreno, L1
Butler, AR; Mazzei, FA; Megson, IL; Miller, MR; Roseberry, MJ; Webb, DJ1
Chen, SJ; Lin, CI; Wu, CC; Yang, SN; Yen, MH1
Hashida-Okumura, A; Iimori, S; Kobayashi, K; Kobayashi, Y; Nagai, K; Nakashima, H1
Karlsson, AM; Loitto, VM; Nilsson, HM; Sundqvist, T; Svensson, SP1
Ellis, DZ; Nathanson, JA; Sweadner, KJ1
Genade, S; Lochner, A; Marais, E; Moolman, JA1
Aldinucci, C; Benocci, A; Frosini, M; Meini, A; Palmi, M; Pessina, G; Sgaragli, G; Youmbi, GT1
Al-Hassani, M; Gupta, MP; Hart, CM; Natarajan, V; Ober, MD; Patterson, C1
Ikeo, T; Inoue, H; Kikkawa, K; Mochida, H; Noto, T; Takagi, M; Yano, K1
Axer, H; Steinbusch, HW; Teunissen, CE1
Eguchi, D; Katusic, ZS1
Aonuma, H; Newland, PL1
Dusting, GJ; Jiang, F1
De Iuri, L; Imbrogno, S; Mazza, R; Tota, B1
Savage, T; Tribe, RM; Yaqoob, MM1
Gitlin, JM; Mitchell, JA; Stanford, SJ1
Granados-Soto, V; Lázaro-Ibáñez, GG; Torres-López, JE1
Chen, IJ; Chiang, LC; Lin, CY; Lin, RJ; Shen, KP; Wu, BN1
Carey, RM; Jin, XH; Siragy, HM1
Barron, LA; Giardina, JB; Granger, JP; Khalil, RA1
Adler-Graschinsky, E; Mendizábal, VE; Orliac, ML1
Antunes, E; Conran, N; de Nucci, G; Ferreira, HH; Lorand-Metze, I; Thomazzi, SM1
Martin, W; McNeish, AJ; Wilson, WS1
Antunes, E; Conran, N; De Nucci, G; Ferreira, HH; Thomazzi, SM1
Bishop, CD; Brandhorst, BP1
Leclere, PG; Lefebvre, RA1
Barreiro, EJ; Noël, F; Silva, CL1
Bryan, RM; Schildmeyer, LA1
Alexander, BT; Davis, JR; Giardina, JB; Granger, JP; Green, GM; Khalil, RA1
Gutiérrez, AM; Liu, R; Persson, AEG; Ring, A1
Galle, J; Ibarra-Alvarado, C; Mameghani, A; Melichar, VO; Schmidt, HH1
Blanco, CE; De Mey, JG; Pulgar, V; Ruijtenbeek, K; Villamor, E1
Chai, CY; Kao, LS; Tang, FI; Wang, Y; Wu, WC1
Fonnum, F; Mariussen, E; Myhre, O; Reistad, T1
Antunes, E; Conran, N; De Nucci, G; Ferreira, HH; Kandratavicius, L; Lodo, ML; Martins, AR; Salaroli, AF1
Liu, R; Persson, AE1
Bnouham, M; Fischmeister, R; Hoerter, J; Legssyer, A; Mekhfi, H; Tahri, A; Ziyyat, A1
Beranova, P; Boucher, JL; Callizot, N; Chalupsky, K; Entlicher, G; Mansuy, D; Muller, B; Schott, C; Stoclet, JC; Vetrovsky, P1
Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ1
Castillo, C; Castillo, EF; Gil-Gastelum, O; Larios, FJ; Valencia, I1
Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC1
Bloodsworth, A; Chumley, PH; Eiserich, JP; Freeman, BA; Krishna, NR; Lim, DG; O'Donnell, VB; Schopfer, F; Sweeney, S; White, CR1
Cellek, S; Hobbs, AJ; Kalsi, JS; Kell, PD; Moncada, S; Ralph, DJ; Rees, RW; Royle, M1
Cao, J; Inoue, M; Kitazawa, T; Taneike, T1
Akimoto, Y; Horinouchi, T; Koike, K; Matsushita, M; Okamoto, T; Shibano, M; Tanaka, Y; Yamaki, F; Yamashita, Y1
Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z1
Beckman, DL; Liu, L; Mehta, P; Sun, P; Wang, J1
Fujimaru, S; Matsubara, K; Ohtaki, K; Saito, O; Shimizu, K; Shiono, H1
Antunes, E; Conran, N; de Nucci, G; Ferreira, HH; Gambero, A1
Garfield, RE; Jain, V; Longo, M; Saade, GR; Vedernikov, YP1
Matsubara, K; Ohtaki, K; Shimizu, K; Shiono, H1
Hobbs, AJ; MacAllister, RJ; Madhani, M; Scotland, RS1
Befus, AD; Cass, C; Graham, K; Marcet-Palacios, M; Mayers, I; Radomski, MW1
Chen, CT; Chou, CJ; Lu, MK; Tsai, TH; Tseng, HW; Wang, GJ1
Ozdem, SS; Sadan, G; Tasatargil, A1
Cameron, JS; Hemmett, HM; Hoffmann, KE; Kronsteiner, A; Lee, CM; Zia, C1
Goldstein, I; Jeong, SJ; Kim, NN; Kim, SW; Munarriz, R; Traish, AM1
Anderson, TJ; Ellis, A; Pannirselvam, M; Triggle, CR1
Cho, KW; Cui, Y; Kim, HJ; Koh, GY; Oh, HK; Park, JK1
Ambrosio, SR; da Costa, FB; de Oliveira, AM; Tirapelli, CR1
Barahona, MV; Benedito, S; García-Sacristán, A; Hernández, M; Martínez, AC; Orensanz, LM; Prieto, D; Recio, P; Rivera, L1
Kolo, LL; Macarthur, H; Westfall, TC1
Déciga-Campos, M; López-Muñoz, FJ1
Anesetti, G; Barbeito, L; Beckman, JS; Cassina, P; Castellanos, R; Martinez-Palma, L; Pehar, M; Peluffo, H1
Antunes, E; Baracat, JS; De Nucci, G; de Oliveira, JF; Fregonesi, A; Okuyama, CE; Priviero, FB; Rodrigues Netto, N; Teixeira, CE1
Carey, RM; Felder, RA; Gildea, JJ; Jin, XH; McGrath, HE; Siragy, HM1
Chan, MH; Chen, HH; Chien, TH; Lee, PY1
Khalil, RA; Orshal, JM1
Chang, PR; Chen, YJ; Huang, HC; Huang, YT; Kuo, YR; Sun, YC; Wang, CJ; Wang, FS; Yang, KD; Yang, YJ1
Araki, M; Fujimoto, S; Nagayama, T; Newland, PL; Schuppe, H1
Correia, NC; Guarino, MP; Lautt, WW; Macedo, MP1
Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T1
Ambrósio, AF; Araújo, IM; Carvalho, CM; Verdasca, MJ1
Atkinson, J; Giummelly, P; Mansard, A; Wang, C1
Arroyo, A; Daftary, A; Gandley, RE; Harger, G; Huang, W; Hubel, CA; Jiang, J; Kagan, VE; Pitt, B; Taylor, RN; Tyurin, VA1
Bluyssen, H; Braam, B; de Roos, R; Holstege, F; Joles, JA; Kemmeren, P; Koomans, H1
Dagonnier, M; Laute, MA; Manto, M; Pandolfo, M1
Fowler, L; Pearce, B; Watts, J; Whitton, PS1
Amato, A; Corti, A; Mulè, F; Serio, R1
Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J1
Daly, CJ; Deighan, C; Macmillan, J; McBride, M; McGrath, JC; Shafaroudi, MM; Wokoma, A1
Anctil, M; Pelletier, C; Poulain, I1
Benedito, S; García-Sacristán, A; Hernández, M; Martínez, AC; Prieto, D; Recio, P; Rivera, L1
Dorovini-Zis, K; Prameya, R; Vincent, SR; Wong, D; Wu, V1
Martin, W; Overend, J; Wilson, WS1
Angelini, GD; Jeremy, JY; Jones, R; Persad, R; Shukla, N1
Beranova, P; Boucher, JL; Chalupsky, K; Kleschyov, AL; Mansuy, D; Muller, B; Munzel, T; Schott, C; Stoclet, JC1
Boriboun, C; Marks, JD; Wang, J1
Bianciotti, LG; di Nunzio, A; Hope, SI; Legaz, G; Morgazo, C; Perfume, G; Vatta, MS1
Kamei, J; Saitoh, A; Tamura, N1
Granados-Soto, V; Torres-López, JE1
Grover, GJ; Scholz, PM; Stokes, H; Weiss, HR; Zhang, S1
Cohen, MV; Cui, L; Downey, JM; Kelm, M; Ludolph, B; Philipp, S; Schulz, R1
Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE1
Jin, L; Palmer, T; Priviero, FB; Teixeira, CE; Webb, RC; Ying, Z1
Choi, DH; Kang, DG; Kwon, TO; Lee, HS; Lee, JK; Moon, MK1
Araiza-Saldaña, CI; Bermúdez-Ocaña, DY; Granados-Soto, V; Pérez-Severiano, F; Reyes-García, G1
Alborch, E; Burguete, MC; Castelló-Ruiz, M; Pérez-Asensio, FJ; Salom, JB; Torregrosa, G1
Antunes, E; Baracat, JS; Claudino, MA; De Nucci, G; Priviero, FB; Teixeira, CE; Webb, RC1
de Godoy, MA; de Oliveira, AM; Fukada, SY; Tirapelli, CR1
Priviero, FB; Teixeira, CE; Todd, J; Webb, RC1
Flores-Murrieta, FJ; Granados-Soto, V; Mixcoatl-Zecuatl, T1
Chan, SS; Choi, AO; Jones, RL; Lin, G1
Barthelmebs, M; García, M; Luisa Martín, M; Morán, A; San Román, L1
Aguirre-Crespo, F; Estrada-Soto, S; Javier López-Guerrero, J; Navarrete-Vázquez, G; Vergara-Galicia, J; Villalobos-Molina, R1
Corrêa, FM; Resstel, LB1
Amato, A; Feo, S; Mulè, F; Serio, R; Zizzo, MG1
Adamson, SL; Kulandavelu, S; Langille, BL; Quan, A; Ward, ME1
Broadley, KJ; Gudka, N; Hamrouni, AM1
Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK1
Abu-Soud, HM; Diamond, MP; Gonik, B; Goud, AP; Goud, PT1
Kamikawa, Y; Kojima, S; Ohno, Y; Sasaki, K; Sunagawa, M; Uchida, K1
Draid, M; El-Mahmoudy, A; El-Sayed, M; Khalifa, M; Shiina, T; Shimizu, Y; Takewaki, T1
Chen, JJ; Lee, HH; Shih, CD1
Breschi, MC; Calderone, V; Martelli, A; Martinotti, E; Testai, L1
Eltze, M; Grebe, T; Hatzelmann, A; Klein, T; Kömhoff, M1
Cavalcante, IF; Ribeiro, RA; Rolim, DE; Souza, MH; Vale, ML1
Huang, ZQ; Xu, HB1
Blanco, CE; Fletcher, AJ; Gonzáles-Luis, G; Moreno, L; Pérez-Vizcaíno, F; Villamor, E1
Chen, J; Fan, F; Han, L; Wang, S; Wang, X; Xie, X; Yan, J; Zhou, X1
Baggio, CH; Cipriani, TR; da Silva-Santos, JE; de Souza, LM; Freitas, CS; Graça, C; Marques, MC; Pontarolo, R; Rattmann, YD; Rieck, L; Sassaki, GL1
Grześk, G; Jasiński, M; Masztalerz, M; Piotrowiak, I; Slupski, M; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R; Wlodarczyk, Z1
da-Silva, CA; Del Bel, EA; Echeverry, MB; Ferreira, FR; Salgado, ML1
Cui, S; Liu, W; Shibamoto, T; Takano, H; Zhang, W; Zhao, Z1
Faggio, C; Pidalà, P; Trischitta, F1
Brouckaert, P; Buys, E; Nimmegeers, S; Sips, P; Van de Voorde, J1
Bouallegue, A; Daou, GB; Srivastava, AK1
Del Bel, EA; Echeverry, MB; Guimarães, FS; Iyomasa, M; Spolidório, PC1
Hein, TW; Kuo, L; Nagaoka, T; Yoshida, A1
Fejgin, K; Klamer, D; Pålsson, E; Svensson, L; Wass, C1
Bendhack, LM; Rocha, ML1
Chang, HM; Chen, GD; Chen, MJ; Lai, CY; Lee, SD; Lin, TB; Pan, SF; Peng, ML; Tung, KC; Wang, PY1
Brito, GA; Gadelha, GG; Garcia, JA; Lima, SJ; Medeiros, JV; Ribeiro, RA; Santos, AA; Soares, PM; Souza, MH1
Furukawa, Y; Horiuchi, K; Kamiyama, S; Komai, M; Ohinata, K; Shirakawa, H; Watanabe-Kamiyama, M1
de Vente, J; Diederen, RM; Hendrikse, F; La Heij, EC; Markerink-van Ittersum, M1
Majewski, H; Zhao, J1
Brouckaert, P; Buys, E; Dhaese, I; Lefebvre, RA; Sips, P; Vanneste, G1
Chen, Z; Dong, XZ; Doran, R; Feldman, M; Ji, G; Kotlikoff, MI; Wei, B; Yin, WX; Zhang, X; Zhao, BL1
Cha, KH; Choi, S; Jeong, HS; Jun, JY; Kim, MY; Kim, YD; Parajuli, SP; Park, CG; Park, JS; Park, YB; Yeum, CH1
Katiyar, SK; Punathil, T1
Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K1
Alves, PM; Queiroga, CS; Vieira, HL1
Katiyar, SK; Punathil, T; Tollefsbol, TO1
Chen, SA; Chen, YC; Chen, YJ; Cheng, CC; Higa, S; Hu, YF1
Dehpour, AR; Ghahremani, MH; Ghasemi, M; Karimollah, AR1
Falzarano, S; Lanzoni, I; Marani, L; Marino, S; Previati, M; Selvatici, R; Siniscalchi, A1
Antunes, E; Priviero, FB; Teixeira, CE; Toque, HA; Webb, RC; Zemse, SM1
Alves, FH; Correa, FM; Crestani, CC; Resstel, LB1
Lograno, MD; Romano, MR1
Mahmoudian, M; Rahbar-Roshandel, N; Rahimi-Moghaddam, P; Tavakoli-Far, B1
Araújo, IG; Athayde-Filho, P; Cavalcante, KV; Correia, Nde A; Dias, KL; Lira, BF; Medeiros, IA; Silva, DF; Silva-Filho, JC1
Hajjhussein, H; Hamza, A; Huang, Y; Li, H; Masood, A; O'Donnell, JM; Wang, W; Xiao, L; Zhan, CG1
Blanco, CE; Villamor, E; Zoer, B1
Batalhao, ME; Branco, LG; Carnio, EC; Ravanelli, MI; Soriano, RN1
Cho, KW; Cui, HZ; Kang, DG; Kim, HY; Lee, HS; Li, X1
Cosgrave, AS; McKay, JS; Thippeswamy, T1
de Montaigu, A; Fernández, E; Galván, A; Sanz-Luque, E1
Castillo, C; Castillo, EF; López, RM; Pérez, T1
Antunes, E; De Nucci, G; Mónica, FZ; Morganti, RP; Toque, HA1
Claes, JM; Holmgren, S; Krönström, J; Mallefet, J1
Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES1
Bahk, JH; Kim, SJ; Park, SJ; Yoo, HY1
Bombarda, G; da Silva, CA; Fazan, R; Sabino, JP; Salgado, HC; Salgado, MC1
Komori, S; Matsuyama, H; Takewaki, T; Unno, T1
Chen, SD; Hwang, CS; Tang, CM; Yang, DI1
Badejo, AM; Bhartiya, M; Haider, U; Kadowitz, PJ; Murthy, SN; Nossaman, BD; Pankey, EA; Stasch, JP1
Antunes, E; Arruda, AM; Barillas, S; Capel, RO; Cogo, JC; De Nucci, G; de Oliveira, MA; Mónica, FZ; Muscará, MN; Nahoum, C; Pissinatti, A; Pissinatti, L; Porto, M; Schenka, AA; Teixeira, SA1
Moonen, RM; Villamor, E1
Bak, YO; Choi, BR; Jeon, JH; Kim, HK; Lee, SW; Park, JK; So, I; Zhao, C1
Chen, XF; Huang, YJ; Lin, DY; Xu, XL; Zhang, W1
Leite-Moreira, AF; Pinho, M; Pires, AL; Seica, R; Sena, CM1
Dinc, B; Karasu, E; Kayacan, N; Sadan, G1
Jantschak, F; Pertz, HH1
Carvalho, FB; Ferreira, J; Girardi, BA; Marisco, PC; Mello, CF; Oliveira, MS; Rubin, MA; Tonello, R1
Cosyns, SM; Lefebvre, RA1
Agazatian, D; Froehlich, O; Kim, YH; Pech, V; Thumova, M; Verlander, JW; Wall, SM; Wang, X1
Aponte, AM; Kohr, MJ; Murphy, E; Steenbergen, C; Sun, J; Tong, G1
Huang, J; Matavelli, LC; Siragy, HM1
Chaudhuri, G; Kawahara, B; Sen, S1
Kang, YH; Morgan, KG; Shin, HM; Yang, IJ1
Andrade E Silva, ML; Bastos, JK; Carvalho, MT; Celotto, AC; Cunha, WR; Evora, PR; Rezende, KC1
Suksamrarn, S; Tep-Areenan, P1
Gurung, YB; Shiina, T; Shimizu, Y; Suzuki, Y; Takewaki, T1
Frink, TJ; Kadowitz, PJ; Lasker, GF; Pankey, EA; Walter, KA; Zeitzer, JR1
Abd Elmageed, ZY; Abdel-Mageed, AB; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Pankey, E; Rezk, B; Sikka, SC1
Cervantes-Durán, C; Espinosa de los Monteros-Zuñiga, A; Godínez-Chaparro, B; Izquierdo, T; Lozada, MC1
Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Quiñonez-Bastidas, GN; Rocha-González, HI1
Blanco-Rivero, J; del Campo, L; Ferrer, M; Martín, MC; Martorell, A; Navarro, R; Sagredo, A1
Choi, SK; Hyman, AL; Kadowitz, PJ; Kassan, M; Matrougui, K; Nossaman, BD; Pankey, EA1
Breslin, JW; Kurtz, KH; Moor, AN; Souza-Smith, FM1
Chavarría-Bolaños, D; Isiordia-Espinoza, MA; Pérez-Urizar, J; Pozos-Guillén, A1
Aalkjaer, C; Bek, T; El-Galaly, A; Kringelholt, SK; Misfeldt, MW1
Alexander, SP; Garle, MJ; Randall, MD; Roberts, RE; Wong, PS1
Kang, P; Seol, GH1
Ebrahimi, SA; Mahmoudian, M; Rahbar-Roshandel, N; Vahabzadeh, G1
Carter, RE; Chen, G; Cramer, SW; Ebner, TJ; Popa, LS1
García, M; García-Pedraza, JÁ; Martín, ML; Morán, A1
Lueptow, LM; O'Donnell, JM; Zhan, CG1
Andrianov, VV; Bogodvid, TKh; Gainutdinov, KhL; Muranova, LN1
Adachi, T; Fujisawa, S; Hongoh, M; Ohba, T; Ono, K; Shimbo, T1
Geibel, JP; Kitay, AM; Link, A1
Belke, D; Dean, JLE; El-Daly, M; Hirota, SA; Hollenberg, MD; Mihara, K; O'Brien, ER; Pulakazhi Venu, VK; Saifeddine, M1
Antoniali, C; Bendhack, LM; da Silva, RS; Grando, MD; Graton, ME; Potje, SR; Troiano, JA1
Chandrasekaran, G; Kumar, D; Kumar, T; Mahobiya, A; Parida, S; Rungsung, S; Singh, TU1
Birulina, YG; Gusakova, SV; Kovalev, IV; Nosarev, AV; Petrova, IV; Rydchenko, VS; Smagliy, LV; Yartseva, YO1
Assreuy, J; Barp, CG; Benedet, PO1
Almanza-Pérez, JC; Arias-Durán, L; Estrada-Soto, S; Hernández-Morales, M; Ibarra-Barajas, M; Millán-Pacheco, C; Navarrete-Vázquez, G; Villalobos-Molina, R1

Other Studies

259 other study(ies) available for quinoxalines and ng-nitroarginine methyl ester

ArticleYear
Endogenous nitric oxide modulates sympathetic neuroeffector transmission in the isolated rabbit lateral saphenous vein.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Electric Stimulation; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phenylephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Synaptic Transmission

1992
Pharmacological modification of glutamate neurotoxicity in vivo.
    Brain research, 1993, Nov-26, Volume: 629, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzofurans; Blood Pressure; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Male; Microdialysis; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrimidines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors

1993
A functional role for nitric oxide in locus coeruleus: immunohistochemical and electrophysiological studies.
    Experimental brain research, 1994, Volume: 98, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Electrophysiology; Evoked Potentials; Hemoglobins; Immunohistochemistry; In Vitro Techniques; Locus Coeruleus; Male; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Tyrosine 3-Monooxygenase

1994
NG-nitro-L-arginine protects against hypoxia/hypoglycemia-induced decrease in CA1 presynaptic spikes in rat hippocampal slices.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Molsidomine; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1995
Adrenoceptor-stimulated endothelium-dependent relaxation in porcine intrapulmonary arteries.
    Pulmonary pharmacology, 1994, Volume: 7, Issue:5

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Pulmonary Artery; Quinoxalines; Swine; Yohimbine

1994
Long-term administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX) alters alpha 2-adrenoceptor-mediated effects at the pre- but not at the postjunctional level.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arteries; Brimonidine Tartrate; Hypertension; Male; Neuroeffector Junction; NG-Nitroarginine Methyl Ester; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P1; Tail; Xanthines

1994
Nitric oxide modulates sympathetic vasoconstriction and basal blood flow in normal and acutely inflamed rabbit knee joints.
    Experimental physiology, 1993, Volume: 78, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arthritis; Blood Pressure; Brimonidine Tartrate; Clonidine; Electric Stimulation; Infusions, Intra-Arterial; Knee Joint; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Quinoxalines; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction

1993
Influences of the endothelium and hypoxia on alpha 1- and alpha 2-adrenoceptor-mediated responses in the rabbit isolated pulmonary artery.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Arginine; Brimonidine Tartrate; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Oxygen; Phenylephrine; Pulmonary Artery; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction

1993
Stimulation of alpha 2 adrenoceptors dilates the rat middle cerebral artery.
    Anesthesiology, 1996, Volume: 85, Issue:1

    Topics: Animals; Arginine; Brimonidine Tartrate; Cerebral Arteries; Cerebrovascular Circulation; Dioxanes; Dose-Response Relationship, Drug; GTP-Binding Proteins; Idazoxan; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Vasodilation

1996
Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium-independent relaxation of rat isolated small mesenteric arteries.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetonitriles; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arginine; Brimonidine Tartrate; Cyclooxygenase Inhibitors; Dopamine; Dopamine Antagonists; In Vitro Techniques; Indomethacin; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phenoxybenzamine; Prostaglandin Endoperoxides, Synthetic; Quinoxalines; Rats; Rats, Wistar; Receptors, Dopamine; Serotonin Antagonists; Splanchnic Circulation; Thromboxane A2; Vasoconstrictor Agents

1995
Effects of site-selective NMDA receptor antagonists in an elevated plus-maze model of anxiety in mice.
    European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1

    Topics: Amino Acids; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phencyclidine; Punishment; Quinoxalines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

1995
Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.
    European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Gerbillinae; Indazoles; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Quinoxalines

1996
Nitric oxide inhibition simulates the enhancement of alpha 1 agonist-induced vasoconstriction in diabetes.
    The Journal of surgical research, 1997, Jul-01, Volume: 70, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstriction

1997
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate.
    Brain research, 1997, Jul-11, Volume: 762, Issue:1-2

    Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity

1997
Cardiovascular effects of nitric oxide and N-methyl-D-aspartate receptors in the nucleus tractus solitarii of rats.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:6

    Topics: Animals; Arginine; Blood Pressure; Brain Mapping; Brain Stem; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus

1997
Tetrahydrobiopterin modulates cyclooxygenase-2 expression in human mesangial cells.
    Biochemical and biophysical research communications, 1997, Dec-08, Volume: 241, Issue:1

    Topics: Biopterins; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Methotrexate; NG-Nitroarginine Methyl Ester; Oxadiazoles; Prostaglandin-Endoperoxide Synthases; Pteridines; Pterins; Quinoxalines; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha

1997
Cyclic guanosine 3',5'-monophosphate-mediated neuroprotection by nitric oxide in dissociated cultures of rat dorsal root ganglion neurones.
    Brain research, 1997, Nov-07, Volume: 774, Issue:1-2

    Topics: Animals; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Spinal; Guanylate Cyclase; Male; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar

1997
Nerve-induced release of nitric oxide exerts dual effects on nicotinic transmission within the coeliac ganglion in the rabbit.
    Neuroscience, 1998, Volume: 84, Issue:1

    Topics: Animals; Arginine; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia; Ganglia, Sympathetic; Male; Neurons; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide; Nitroarginine; Oxadiazoles; Quinoxalines; Rabbits; Splanchnic Nerves; Synapses; Synaptic Transmission; Time Factors

1998
Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, May-15, Volume: 18, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cyclic GMP; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Fetus; Guanylate Cyclase; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Oxadiazoles; Quinoxalines; Rats; Solubility

1998
Involvement of bradykinin B1 and B2 receptors in relaxation of mouse isolated trachea.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Dinoprostone; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Trachea

1998
A transient dilatation of pressurised rat cerebral arteries during rapid pressure increases is mediated by nitric oxide.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:2

    Topics: Aminoquinolines; Animals; Arginine; Blood Pressure; Cerebral Arteries; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Temperature; Vasodilation

1998
Nitric oxide-mediated cGMP production in the islands of Calleja in the rat.
    Brain research, 1998, Apr-06, Volume: 789, Issue:1

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Olfactory Bulb; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred Lew; Tissue Distribution

1998
Galanin stimulates the N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in vivo in the rat ventral hippocampus.
    Neuroscience, 1998, Volume: 85, Issue:3

    Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Galanin; Hippocampus; Locomotion; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptide Fragments; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin

1998
Evidence for the involvement of nitric oxide in the inhibitory effect of GSPYFVamide on Helix aspersa central neurones.
    Regulatory peptides, 1998, Jun-30, Volume: 74, Issue:2-3

    Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glutathione; Guanylate Cyclase; Helix, Snails; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nitroso Compounds; Oligopeptides; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitrosoglutathione; Sodium Nitrite

1998
Influence of a selective guanylate cyclase inhibitor, and of the contraction level, on nitrergic relaxations in the gastric fundus.
    British journal of pharmacology, 1998, Volume: 124, Issue:7

    Topics: Animals; Chymotrypsin; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guanylate Cyclase; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar

1998
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Guanidines; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium

1998
Relaxant effects of L-citrulline in rabbit vascular smooth muscle.
    British journal of pharmacology, 1998, Volume: 125, Issue:1

    Topics: Animals; Aorta; Cells, Cultured; Citrulline; Cyclic GMP; Dexamethasone; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polysaccharides; Potassium Channels; Purinones; Quinoxalines; Rabbits

1998
Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia.
    Pain, 1998, Volume: 78, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Colon; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Immunohistochemistry; Male; Medulla Oblongata; Microinjections; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Viscera; Zymosan

1998
Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.
    Neuropharmacology, 1998, Volume: 37, Issue:8

    Topics: Animals; Cell Death; Cyclic GMP; Drug Synergism; Enzyme Inhibitors; Hydrogen Peroxide; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilator Agents

1998
Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
    British journal of pharmacology, 1998, Volume: 125, Issue:6

    Topics: Animals; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Methylene Blue; Mice; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Signal Transduction; Solubility; Trachea; Vasodilator Agents

1998
Nitrergic neurotransmission mediates the non-adrenergic non-cholinergic responses in the clitoral corpus cavernosum of the rabbit.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Animals; Arginine; Clitoris; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Purinones; Quinoxalines; Rabbits; Synaptic Transmission; Tetrodotoxin

1998
Nitric oxide inhibits potassium transport in the rat distal colon.
    The American journal of physiology, 1999, Volume: 276, Issue:1

    Topics: Animals; Arginine; Biological Transport; Colon; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penicillamine; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine

1999
Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells.
    European journal of pharmacology, 1999, Jan-01, Volume: 364, Issue:1

    Topics: Animals; Aorta; Benzoates; Cells, Cultured; Cyclic GMP; Endothelin-1; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitro Compounds; Oxadiazoles; Protein Precursors; Quinoxalines; RNA, Messenger; Swine

1999
P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats.
    Stroke, 1999, Volume: 30, Issue:5

    Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Cerebral Arteries; Cerebrovascular Circulation; Charybdotoxin; Chlorides; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Channels; Potassium Chloride; Quinoxalines; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Tetraethylammonium; Uridine Triphosphate; Vasodilation

1999
Tonic inhibitory action by nitric oxide on spontaneous mechanical activity in rat proximal colon: involvement of cyclic GMP and apamin-sensitive K+ channels.
    British journal of pharmacology, 1999, Volume: 127, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colon; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Potassium Channels; Purinones; Quinoxalines; Rats; Rats, Wistar

1999
Effects of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and Nomega(6)-nitro-L-arginine methyl ester (NAME) on cyclic GMP levels during muscarinic activation of tracheal smooth muscle.
    Biochemical pharmacology, 1999, Aug-15, Volume: 58, Issue:4

    Topics: Animals; Carbachol; Cattle; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Muscarinic Agonists; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Muscarinic; Trachea

1999
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1999
Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-D-aspartate receptors and glucocorticoids.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cortical Spreading Depression; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Disease Susceptibility; Dizocilpine Maleate; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Indomethacin; Isoenzymes; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Parietal Lobe; Phospholipases A; Phospholipases A2; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcriptional Activation

1999
Effects of L-arginine on the afferent resting activity in the cephalopod statocyst.
    Brain research, 1999, Oct-16, Volume: 845, Issue:1

    Topics: Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cystamine; DDT; Decapodiformes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hair Cells, Vestibular; Imines; Immunosuppressive Agents; Male; Methylene Blue; Mollusca; NADP; NG-Nitroarginine Methyl Ester; Niacin; Nitric Oxide; Nitroarginine; Oxadiazoles; Postural Balance; Quinoxalines; Sodium Chloride

1999
5-hydroxytryptamine- and U46619-mediated vasoconstriction in bovine pulmonary conventional and supernumerary arteries: effect of endogenous nitric oxide.
    Clinical science (London, England : 1979), 2000, Volume: 98, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Serotonin; Serotonin Antagonists; Urea; Vasoconstrictor Agents

2000
In vitro, nitric oxide (NO) stimulates LH secretion and partially prevents the inhibitory effect of dopamine on PRL release.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:10

    Topics: Aminoquinolines; Animals; Cells, Cultured; Cyclic GMP; Dopamine; Enzyme Inhibitors; Guanylate Cyclase; Luteinizing Hormone; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Pituitary Gland, Anterior; Prolactin; Quinoxalines; Rats; Rats, Wistar

1999
Pharmacological evidence for both neuronal and smooth muscular PAC1 receptors and a VIP-specific receptor in rat colon.
    Regulatory peptides, 1999, Dec-23, Volume: 85, Issue:2-3

    Topics: Animals; Apamin; Colon; Female; Indazoles; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Tetrodotoxin; Vasoactive Intestinal Peptide

1999
Evidence for the participation of the nitric oxide-cyclic GMP pathway in the antinociceptive action of meloxicam in the formalin test.
    European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Meloxicam; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Thiazines; Thiazoles

2000
Endothelium-dependent sensory non-adrenergic non-cholinergic vasodilatation in rat thoracic aorta: involvement of ATP and a role for NO.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:4

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Evans Blue; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline; Triazines; Vasodilation

2000
Pharmacological characterization of neurogenic responses of the sheep isolated internal anal sphincter.
    British journal of pharmacology, 2000, Volume: 130, Issue:3

    Topics: Anal Canal; Animals; Autonomic Nervous System; Calcium; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Muscle Contraction; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Sheep

2000
Role of endothelium/nitric oxide in atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Oxadiazoles; Phenoxyacetates; Phenoxypropanolamines; Phenylacetates; Pindolol; Propanolamines; Propranolol; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Vasodilation

2000
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
    Mediators of inflammation, 2000, Volume: 9, Issue:1

    Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2000
Sildenafil relaxes rabbit clitoral corpus cavernosum.
    Life sciences, 2000, May-26, Volume: 67, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Clitoris; Electric Stimulation; Female; Guanylate Cyclase; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Sildenafil Citrate; Sulfones; Synaptic Transmission; Tetrodotoxin

2000
Mechanisms of nitric oxide-independent relaxations induced by carbachol and acetylcholine in rat isolated renal arteries.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Acetylcholine; Animals; Carbachol; Charybdotoxin; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indomethacin; Male; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Oxadiazoles; Peptides; Phenylephrine; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Artery; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2000
Role of central glutamate receptors, nitric oxide and soluble guanylyl cyclase in the inhibition by endotoxin of rat gastric acid secretion.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Animals; Benzoates; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Glycine; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pentagastrin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solubility; Stomach; Vagotomy

2000
Novel S-nitrosothiols do not engender vascular tolerance and remain effective in glyceryl trinitrate-tolerant rat femoral arteries.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Femoral Artery; Glucosamine; Glutathione; Hemoglobins; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroglycerin; Nitroso Compounds; Oxadiazoles; Penicillamine; Perfusion; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2000
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Hypotension; Lipopolysaccharides; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pinacidil; Potassium Channels; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium; Vasodilation; Vasodilator Agents

2000
Increase in peripheral blood flow due to extraocular direct irradiation of visible light in rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:3

    Topics: Animals; Blood Flow Velocity; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eye Protective Devices; Injections, Intraperitoneal; Laser-Doppler Flowmetry; Lasers; Light; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Regional Blood Flow; Skin; Tail; Vasodilator Agents

2000
Inhibitory effect of cyclic guanosine 3',5'-monophosphate (cGMP) on the afferent resting activity in the cephalopod statocyst.
    Brain research, 2000, Oct-13, Volume: 880, Issue:1-2

    Topics: Afferent Pathways; Animals; Cyclic GMP; Cystamine; Decapodiformes; Dibutyryl Cyclic GMP; Dideoxyadenosine; Enzyme Inhibitors; Imines; Methylene Blue; Mollusca; NG-Nitroarginine Methyl Ester; Niacin; Nitroarginine; Oxadiazoles; Quinoxalines; Sense Organs

2000
Nitric oxide modulates intracellular translocation of pigment organelles in Xenopus laevis melanophores.
    Cell motility and the cytoskeleton, 2000, Volume: 47, Issue:3

    Topics: Alkaloids; Animals; Arginine; Biological Transport; Blotting, Western; Carbazoles; Cells, Cultured; Cyclic GMP; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Guanylate Cyclase; Indoles; Melanophores; Microscopy, Fluorescence; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Signal Transduction; Time Factors; Xenopus laevis

2000
Carbachol inhibits Na(+)-K(+)-ATPase activity in choroid plexus via stimulation of the NO/cGMP pathway.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6

    Topics: Adenosine Triphosphate; Animals; Carbachol; Cattle; Cholinergic Agonists; Choroid Plexus; Cyclic GMP; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Ouabain; Oxadiazoles; Phosphorylation; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Solubility; Thionucleotides; Triazenes; Vasodilator Agents

2000
Nitric oxide: a trigger for classic preconditioning?
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Adenosine Monophosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Epinephrine; Guanylate Cyclase; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sympathomimetics; Vasodilator Agents

2000
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24

    Topics: Aminoquinolines; Animals; Arginine; Astrocytoma; Calcium; Corpus Striatum; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heparin; Humans; Hydrazines; In Vitro Techniques; Interleukin-1; Intracellular Fluid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Spermine; Tumor Cells, Cultured

2000
Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Oxidants; Penicillamine; Phosphodiesterase Inhibitors; Pulmonary Artery; Quinoxalines; Swine; Thionucleotides

2001
Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Papaverine; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Pyridines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetrodotoxin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2001
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
    Brain research. Developmental brain research, 2000, Dec-29, Volume: 125, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Techniques; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Pregnancy; Quinoxalines; Rats; Rats, Inbred Lew; Signal Transduction; Vasodilator Agents

2000
Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Calcium; Colforsin; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; In Vitro Techniques; Indomethacin; Ionophores; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Potassium Chloride; Quinoxalines; Saphenous Vein; Vasoconstrictor Agents; Vasodilation

2001
Opposing actions of nitric oxide on synaptic inputs of identified interneurones in the central nervous system of the crayfish.
    The Journal of experimental biology, 2001, Volume: 204, Issue:Pt 7

    Topics: Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Ganglia, Invertebrate; Imidazoles; In Vitro Techniques; Interneurons; Male; Mechanoreceptors; Nerve Net; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Synapses; Synaptic Transmission

2001
Endothelium-dependent vasorelaxation independent of nitric oxide and K(+) release in isolated renal arteries of rats.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Acetylcholine; Animals; Barium; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Glycyrrhetinic Acid; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ouabain; Oxadiazoles; Potassium; Quinoxalines; Rats; Rats, Inbred WKY; Renal Artery; Vasodilation; Vasodilator Agents

2001
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla.
    The Journal of experimental biology, 2001, Volume: 204, Issue:Pt 10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Anguilla; Animals; Arginine; Atropine; Detergents; Enzyme Inhibitors; Female; Free Radical Scavengers; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Molsidomine; Muscarinic Antagonists; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Octoxynol; omega-N-Methylarginine; Ornithine; Oxadiazoles; Parasympatholytics; Pirenzepine; Quinoxalines; Superoxide Dismutase

2001
Flow induces dilatation in the femoral artery of uraemic rats but constriction in control rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:6

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Electrolytes; Enzyme Inhibitors; Femoral Artery; Hemoglobins; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Reference Values; Regional Blood Flow; Uremia; Vasodilation

2001
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation

2001
Phentolamine mesylate relaxes rabbit corpus cavernosum by a nonadrenergic, noncholinergic mechanism.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Penis; Phentolamine; Quinoxalines; Rabbits; Tetrodotoxin

2001
Participation of the nitric oxide-cyclic GMP-ATP-sensitive K(+) channel pathway in the antinociceptive action of ketorolac.
    European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2

    Topics: Adenosine Triphosphate; Analgesics; Animals; Behavior, Animal; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glyburide; Guanylate Cyclase; Ketorolac; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Penicillamine; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2001
A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Cromakalim; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heart Rate; In Vitro Techniques; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphoric Diester Hydrolases; Piperidines; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Solubility; Vasodilation; Vasodilator Agents; Xanthine; Xanthines

2001
Renal interstitial cGMP mediates natriuresis by direct tubule mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Arginine; Bacterial Toxins; Benzimidazoles; Consciousness; Cyclic AMP; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Female; Glomerular Filtration Rate; Kidney; Kidney Tubules; Microscopy, Fluorescence; Natriuresis; Nephrectomy; NG-Nitroarginine Methyl Ester; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Thionucleotides; Xanthenes

2001
High-salt diet enhances vascular reactivity in pregnant rats with normal and reduced uterine perfusion pressure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Nitroprusside; Oxadiazoles; Phenylephrine; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Uterus; Vasoconstrictor Agents; Vasodilator Agents

2001
Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed.
    European journal of pharmacology, 2001, Sep-21, Volume: 427, Issue:3

    Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents

2001
Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface.
    British journal of pharmacology, 2001, Volume: 134, Issue:3

    Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Separation; Cyclic GMP; Enzyme Inhibitors; Eosinophils; Fibronectins; Humans; Integrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines

2001
Dominant role of an endothelium-derived hyperpolarizing factor (EDHF)-like vasodilator in the ciliary vascular bed of the bovine isolated perfused eye.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Barium; Biological Factors; Blood Vessels; Bradykinin; Cattle; Charybdotoxin; Ciliary Body; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Eye; Flurbiprofen; Glyburide; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Ouabain; Oxadiazoles; Perfusion; Potassium; Potassium Channel Blockers; Pressure; Quinoxalines; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2001
Role of nitric oxide on in vitro human eosinophil migration.
    Biochemical pharmacology, 2001, Nov-15, Volume: 62, Issue:10

    Topics: Cell Movement; Chemotaxis; Drug Interactions; Enzyme Inhibitors; Eosinophils; Guanylate Cyclase; Humans; Imidazoles; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines

2001
NO/cGMP signaling and HSP90 activity represses metamorphosis in the sea urchin Lytechinus pictus.
    The Biological bulletin, 2001, Volume: 201, Issue:3

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Female; Guanylate Cyclase; HSP90 Heat-Shock Proteins; Lactones; Macrolides; Male; Metamorphosis, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Sea Urchins; Signal Transduction

2001
Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Atropine; Benzofurans; Brimonidine Tartrate; Dioxanes; Enzyme Inhibitors; Evoked Potentials; Female; Gastric Fundus; Gastrointestinal Agents; Humans; Male; Middle Aged; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Piperidines; Quinoxalines; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Receptors, Vasoactive Intestinal Peptide; Serotonin Antagonists; Stomach; Synaptic Transmission; Vasoactive Intestinal Peptide; Yohimbine

2002
Cyclic GMP-dependent vasodilatory properties of LASSBio 294 in rat aorta.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanylate Cyclase; Hydrazones; In Vitro Techniques; Indomethacin; Male; Molecular Structure; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Thiophenes; Vasoconstriction; Vasodilator Agents

2002
Effect of NO on EDHF response in rat middle cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Factors; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Middle Cerebral Artery; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Long-Evans; Thionucleotides; Vasodilation

2002
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:2

    Topics: Acetylcholine; Animals; Antineoplastic Agents; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Phenylephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Quinoxalines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2002
Nitric oxide induces resensitization of P2Y nucleotide receptors in cultured rat mesangial cells.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Glomerular Mesangium; Guanylate Cyclase; Intracellular Membranes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Oxadiazoles; Quinoxalines; Rats; Receptors, Purinergic P2; Ryanodine Receptor Calcium Release Channel

2002
Phosphorylation of blood vessel vasodilator-stimulated phosphoprotein at serine 239 as a functional biochemical marker of endothelial nitric oxide/cyclic GMP signaling.
    Molecular pharmacology, 2002, Volume: 61, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Biomarkers; Cell Adhesion Molecules; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Kinetics; Male; Microfilament Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Phosphoproteins; Phosphorylation; Quinoxalines; Rabbits; Serine; Signal Transduction; Thionucleotides

2002
Vascular reactivity in intrapulmonary arteries of chicken embryos during transition to ex ovo life.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3

    Topics: Animals; Animals, Newborn; Chick Embryo; Enzyme Inhibitors; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pulmonary Artery; Quinoxalines; Vasoconstriction; Vasodilation; Vasomotor System

2002
Nitric oxide reduces blood pressure in the nucleus tractus solitarius: a real time electrochemical study.
    Brain research bulletin, 2002, Jan-15, Volume: 57, Issue:2

    Topics: Animals; Arginine; Biosensing Techniques; Blood Pressure; Bradycardia; Cats; Computer Systems; Electrochemistry; Enzyme Inhibitors; Extracellular Space; Female; Guanosine Monophosphate; Guanylate Cyclase; Hemoglobins; Hypertension; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pressoreceptors; Quinoxalines; Reflex; Sensitivity and Specificity; Solitary Nucleus; Tachycardia; Vagotomy

2002
The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species.
    Toxicology and applied pharmacology, 2002, Mar-15, Volume: 179, Issue:3

    Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Chlorodiphenyl (54% Chlorine); Cyclosporine; Cytoplasmic Granules; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2002
Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects.
    European journal of pharmacology, 2002, May-03, Volume: 442, Issue:1-2

    Topics: Cell Movement; Chemokine CCL11; Chemokines, CC; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Guanylate Cyclase; Humans; Isoenzymes; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Rhinitis, Allergic, Perennial; S-Nitroso-N-Acetylpenicillamine; Solubility

2002
Effects of nitric oxide on P2Y receptor resensitization in spontaneously hypertensive rat mesangial cells.
    Journal of hypertension, 2002, Volume: 20, Issue:9

    Topics: Adenosine Triphosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Inhibitors; Glomerular Mesangium; Guanylate Cyclase; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; Osmolar Concentration; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic P2; Spermine

2002
Arbutus unedo induces endothelium-dependent relaxation of the isolated rat aorta.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:6

    Topics: Animals; Aorta, Thoracic; Atropine; Carbachol; Dogs; Drug Interactions; Endothelium, Vascular; Ericaceae; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Norepinephrine; Oxadiazoles; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation

2002
Involvement of NO in the endothelium-independent relaxing effects of N(omega)-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indicators and Reagents; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH-Ferrihemoprotein Reductase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organic Cation Transport Proteins; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar

2002
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine

2002
Endothelial inhibitory modulation on the contractile responses to alpha 2-adrenergic agonists.
    Proceedings of the Western Pharmacology Society, 2002, Volume: 45

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxymetazoline; Quinoxalines; Rats; Rats, Wistar

2002
Role of the nitric oxide-cyclic GMP-K+ channel pathway in the antinociception induced by atrial natriuretic peptide (ANP) and diclofenac.
    Proceedings of the Western Pharmacology Society, 2002, Volume: 45

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atrial Natriuretic Factor; Charybdotoxin; Cyclic GMP; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pain Measurement; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Tolbutamide

2002
Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-10, Volume: 99, Issue:25

    Topics: Animals; Aorta, Thoracic; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Free Radical Scavengers; Guanylate Cyclase; Inflammation; Linoleic Acids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitro Compounds; Oxadiazoles; Oxidation-Reduction; Oxyhemoglobins; Quinoxalines; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Vasodilation

2002
BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.
    The Journal of urology, 2003, Volume: 169, Issue:2

    Topics: Animals; Guanylate Cyclase; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Penis; Pyrazoles; Pyridines; Quinoxalines; Rabbits

2003
5-HT7 receptor-mediated relaxation of the oviduct in nonpregnant proestrus pigs.
    European journal of pharmacology, 2003, Feb-14, Volume: 461, Issue:2-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrous Cycle; Female; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oviducts; Oxadiazoles; Pituitary Adenylate Cyclase-Activating Polypeptide; Purinones; Quinoxalines; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swine; Tritium; Vasoactive Intestinal Peptide

2003
Nitric oxide (NO) primarily accounts for endothelium-dependent component of beta-adrenoceptor-activated smooth muscle relaxation of mouse aorta in response to isoprenaline.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2002, Volume: 38, Issue:4-5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Isoproterenol; Male; Mice; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Oxadiazoles; Propranolol; Quinoxalines; Receptors, Adrenergic, beta; Vasodilation

2002
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases

2003
Effect of nitric oxide on lung surfactant secretion.
    Experimental lung research, 2003, Volume: 29, Issue:5

    Topics: Animals; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Guanidines; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Perfusion; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Quinoxalines; Rats; Rats, Sprague-Dawley; Spermine

2003
Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats.
    Brain research, 2003, Jun-27, Volume: 976, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Herbicides; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Paraquat; Parkinsonian Disorders; Quinoxalines; Rats; Rats, Wistar; Selegiline

2003
Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface.
    Biochemical pharmacology, 2003, Jul-01, Volume: 66, Issue:1

    Topics: Antibodies, Monoclonal; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Fibronectins; Guanylate Cyclase; Humans; Integrin alpha4beta1; Integrins; Macrophage-1 Antigen; Microtubules; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines

2003
Effects of recombinant human relaxin on pregnant rat uterine artery and myometrium in vitro.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:6

    Topics: Adenine; Animals; Arteries; Dose-Response Relationship, Drug; Female; Gestational Age; Humans; Myometrium; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxytocin; Pregnancy; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Relaxin; Uterine Contraction

2003
Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.
    Neuroscience research, 2003, Volume: 46, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Animals, Newborn; Azepines; Cabergoline; Caspases; Cell Count; Cycloheximide; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ergolines; Excitatory Amino Acid Antagonists; Herbicides; Immunohistochemistry; Mesencephalon; NADPH Dehydrogenase; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Paraquat; Piperazines; Protein Synthesis Inhibitors; Quinoxalines; Rats; Rats, Wistar; Selegiline; Tyrosine 3-Monooxygenase

2003
Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Drug Antagonism; Drug Synergism; Guanylate Cyclase; Male; Mesenteric Arteries; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle Relaxation; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Phenylephrine; Polysaccharides; Quinoxalines; Receptors, Atrial Natriuretic Factor; Signal Transduction; Spermine

2003
Nitric oxide and cyclic GMP increase the expression of matrix metalloproteinase-9 in vascular smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Animals; Cells, Cultured; Cyclic GMP; Cyclooxygenase 2; Isoenzymes; Lipopolysaccharides; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; RNA, Messenger; Superoxide Dismutase

2003
The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca(2+)-NO-cGMP pathway.
    Life sciences, 2003, Oct-10, Volume: 73, Issue:21

    Topics: Adenosine; Aorta, Thoracic; Basidiomycota; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Medicine, Chinese Traditional; Mycelium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Plant Extracts; Plants, Medicinal; Quinoxalines; Species Specificity; Tetraethylammonium; Vasodilation; Vasodilator Agents

2003
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
    Autonomic & autacoid pharmacology, 2003, Volume: 23, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline

2003
A role for nitric oxide in hypoxia-induced activation of cardiac KATP channels in goldfish (Carassius auratus).
    The Journal of experimental biology, 2003, Volume: 206, Issue:Pt 22

    Topics: Action Potentials; Analysis of Variance; Animals; Diacetyl; Goldfish; Hypoxia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Penicillamine; Potassium Channels; Quinoxalines; Sarcolemma

2003
Role of the nitric oxide-cyclic GMP pathway in regulation of vaginal blood flow.
    International journal of impotence research, 2003, Volume: 15, Issue:5

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Female; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Regional Blood Flow; Sexual Behavior, Animal; Sildenafil Citrate; Sulfones; Vagina

2003
Catalase has negligible inhibitory effects on endothelium-dependent relaxations in mouse isolated aorta and small mesenteric artery.
    British journal of pharmacology, 2003, Volume: 140, Issue:7

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Apamin; Cardiovascular Agents; Catalase; Charybdotoxin; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Indomethacin; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium Channel Blockers; Potassium Chloride; Quinoxalines; Tetraethylammonium; Vasodilator Agents

2003
Activation of nitric oxide-cyclic guanosine monophosphate signaling in kidney by extracorporeal shock wave therapy.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Kidney; Lithotripsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Signal Transduction

2003
Evidence for the mechanisms underlying the effects of pimaradienoic acid isolated from the roots of Viguiera arenaria on rat aorta.
    Pharmacology, 2004, Volume: 70, Issue:1

    Topics: Animals; Aorta, Thoracic; Asteraceae; Brazil; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Oxadiazoles; Phenylephrine; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasodilation

2004
Heterogeneity of neuronal and smooth muscle receptors involved in the VIP- and PACAP-induced relaxations of the pig intravesical ureter.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apamin; Capsaicin; Charybdotoxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanylate Cyclase; Male; Muscle, Smooth; Neurons, Afferent; Neuropeptide Y; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-Conotoxin GVIA; Oxadiazoles; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels, Calcium-Activated; Quinoxalines; Receptors, Calcitonin Gene-Related Peptide; Receptors, Peptide; Receptors, Vasoactive Intestinal Peptide; Rolipram; Sensory Receptor Cells; Swine; Tetraethylammonium; Ureter; Vasoactive Intestinal Peptide

2004
Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:1

    Topics: Animals; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Perfusion; Pressure; Quinoxalines; Rats; Vasomotor System

2004
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.
    Proceedings of the Western Pharmacology Society, 2003, Volume: 46

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoenzymes; Lactones; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Sulfones; Uric Acid

2003
Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors.
    Neurotoxicity research, 2003, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Cell Count; Cell Death; Cells, Cultured; Culture Media; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Kainic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Peroxynitrous Acid; Quinoxalines; Rats; Rats, Wistar; Spinal Cord; Stem Cells; Tyrosine

2003
Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.
    Urology, 2004, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Child; Cyclic GMP; Drug Evaluation, Preclinical; Electric Stimulation; Enzyme Inhibitors; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penis; Phenylephrine; Piperazines; Priapism; Purines; Quinoxalines; Scorpion Venoms; Second Messenger Systems; Sildenafil Citrate; Sodium Channel Blockers; Sulfones; Tetrodotoxin

2004
Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenalectomy; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Denervation; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Guanylate Cyclase; Hypertension; Ion Transport; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Natriuresis; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sodium; Soluble Guanylyl Cyclase; Thionucleotides

2004
Involvement of NO/cGMP pathway in toluene-induced locomotor hyperactivity in female rats.
    Psychopharmacology, 2004, Volume: 176, Issue:3-4

    Topics: Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Hyperkinesis; Injections, Intraperitoneal; Motor Activity; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toluene

2004
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Female; Interleukin-6; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxadiazoles; Phenylephrine; Pregnancy; Pregnancy, Animal; Progesterone; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2004
Nitric oxide mediates ultrasound-induced hypoxia-inducible factor-1alpha activation and vascular endothelial growth factor-A expression in human osteoblasts.
    Bone, 2004, Volume: 35, Issue:1

    Topics: Calcium; Cell Line; Dinoprostone; Endothelial Cells; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoblasts; Oxadiazoles; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Transcription, Genetic; Ultrasonics; Vascular Endothelial Growth Factor A

2004
Nitric oxide modulates local reflexes of the tailfan of the crayfish.
    Journal of neurobiology, 2004, Volume: 60, Issue:2

    Topics: Analysis of Variance; Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Imidazoles; In Vitro Techniques; Male; Muscles; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Picolines; Quinoxalines; Reflex; Thionucleotides

2004
Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:3

    Topics: Acetylcholine; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Injections, Intravenous; Insulin Resistance; Liver; Male; Molsidomine; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Portal Vein; Quinoxalines; Rats; Rats, Wistar; Signal Transduction

2004
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:3

    Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine

2004
Nitric oxide inhibits complex I following AMPA receptor activation via peroxynitrite.
    Neuroreport, 2004, Sep-15, Volume: 15, Issue:13

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Cyclic GMP; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Kainic Acid; Microtubule-Associated Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Proton Pumps; Quinoxalines; Rats; Receptors, AMPA; Tyrosine

2004
Decreased aortic smooth muscle contraction in a rat model of multibacterial sepsis.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6

    Topics: Animals; Aorta; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Sepsis; Soluble Guanylyl Cyclase

2004
S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1

    Topics: Adult; Animals; Ascorbic Acid; Copper; Female; Humans; Mesenteric Arteries; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxidative Stress; Phenylephrine; Pre-Eclampsia; Pregnancy; Quinoxalines; Serum Albumin, Bovine; Vasodilation

2005
Nitric oxide-dependent and nitric oxide-independent transcriptional responses to high shear stress in endothelial cells.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4

    Topics: Binding Sites; Cyclic GMP; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelial Cells; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; High Mobility Group Proteins; Humans; Immediate-Early Proteins; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nuclear Proteins; Oxadiazoles; Quinoxalines; SOX9 Transcription Factor; SOXD Transcription Factors; Stress, Mechanical; Transcription Factors; Transcription, Genetic

2005
Effects of levetiracetam on the production of nitric oxide--an in vivo study.
    Journal of neurology, 2005, Volume: 252, Issue:6

    Topics: Analysis of Variance; Animals; Anticonvulsants; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Levetiracetam; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piracetam; Quinoxalines; Rats; Rats, Wistar; Time Factors

2005
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
    Brain research bulletin, 2005, May-30, Volume: 65, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness

2005
Inhibitory influence of chromogranin A N-terminal fragment (vasostatin-1) on the spontaneous contractions of rat proximal colon.
    Regulatory peptides, 2005, Aug-15, Volume: 130, Issue:1-2

    Topics: Animals; Apamin; Calreticulin; Chromogranin A; Chromogranins; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Tract; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptide Fragments; Peptides; Pressure; Protein Structure, Tertiary; Quinoxalines; Rats; Rats, Wistar; Recombinant Proteins; Tetrodotoxin; Time Factors

2005
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms

2005
Two "knockout" mouse models demonstrate that aortic vasodilatation is mediated via alpha2a-adrenoceptors located on the endothelium.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Animals; Aorta, Thoracic; Brimonidine Tartrate; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Image Processing, Computer-Assisted; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents; Vasodilation

2005
Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 10

    Topics: Animals; Anthozoa; Body Fluids; California; Guanidines; Immunohistochemistry; Indazoles; Muscle Contraction; Muscles; Neurites; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peristalsis; Phosphodiesterase Inhibitors; Purinones; Quinoxalines

2005
Endothelial mechanisms underlying responses to acetylcholine in the horse deep dorsal penile vein.
    European journal of pharmacology, 2005, May-16, Volume: 515, Issue:1-3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Calcium; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Horses; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Penis; Phenylephrine; Potassium; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Sodium Nitrite; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins

2005
Nitric oxide reduces T lymphocyte adhesion to human brain microvessel endothelial cells via a cGMP-dependent pathway.
    European journal of pharmacology, 2005, May-09, Volume: 514, Issue:2-3

    Topics: Brain; Cell Adhesion; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; Humans; Intercellular Adhesion Molecule-1; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Nitroso Compounds; Oxadiazoles; Platelet Endothelial Cell Adhesion Molecule-1; Quinoxalines; Signal Transduction; T-Lymphocytes; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2005
Biphasic neurogenic vasodilatation in the bovine intraocular long posterior ciliary artery: involvement of nitric oxide and an additional unidentified neurotransmitter.
    British journal of pharmacology, 2005, Volume: 145, Issue:7

    Topics: Animals; Cattle; Ciliary Arteries; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Muscle, Smooth, Vascular; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Oxadiazoles; Quinoxalines; Tetrodotoxin; Vasodilation

2005
Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits.
    European journal of pharmacology, 2005, Jul-11, Volume: 517, Issue:3

    Topics: Acetophenones; Allopurinol; Animals; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypercholesterolemia; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Onium Compounds; Oxadiazoles; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Rotenone; Sildenafil Citrate; Sulfones; Superoxides; Uncoupling Agents; Xanthine Oxidase

2005
Nomega-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents.
    European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3

    Topics: Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Imidazoles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Vasodilation; Vasodilator Agents

2005
Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-13, Volume: 25, Issue:28

    Topics: Animals; Animals, Newborn; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Hippocampus; Indazoles; Ion Transport; Mitochondria; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Oxygen; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Compounds; Thiazepines

2005
Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus.
    Biochemical and biophysical research communications, 2005, Sep-02, Volume: 334, Issue:3

    Topics: Animals; Carbazoles; Cyclic GMP; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-3; Hypothalamus, Anterior; Indazoles; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Oligopeptides; Oxadiazoles; Piperidines; Quinoxalines; Rats; Suramin; Tyrosine 3-Monooxygenase

2005
Possible involvement of the spinal nitric oxide/cGMP pathway in vincristine-induced painful neuropathy in mice.
    Pain, 2005, Volume: 117, Issue:1-2

    Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Injections, Spinal; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Reaction Time; Spinal Cord; Time Factors; Vincristine

2005
Peripheral participation of the phosphodiesterase 3 on formalin-evoked nociception.
    European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Injections, Subcutaneous; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors

2005
Negative inotropic effect of low-dose ethanol in mouse ventricular myocytes is mediated by activation of endothelial nitric oxide synthase.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanol; Guanylate Cyclase; In Vitro Techniques; Mice; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines

2005
Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1

    Topics: Androstadienes; Animals; ATP-Binding Cassette Transporters; Cyclic GMP-Dependent Protein Kinases; Deferoxamine; Enzyme Activation; Female; Glyburide; Guanylate Cyclase; Hemodynamics; Hydroxybenzoates; KATP Channels; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Potassium Channels; Potassium Channels, Inwardly Rectifying; Procollagen-Proline Dioxygenase; Proto-Oncogene Proteins c-akt; Quinoxalines; Rabbits; Reactive Oxygen Species; Wortmannin

2006
Mechanisms underlying relaxation of rabbit aorta by BAY 41-2272, a nitric oxide-independent soluble guanylate cyclase activator.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:9

    Topics: Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Pyrazoles; Pyridines; Quinoxalines; Rabbits; Signal Transduction; Sildenafil Citrate; Sulfones; Vasodilation

2005
Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:10

    Topics: Amides; Animals; Blotting, Western; Celiac Artery; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Guanine Nucleotide Exchange Factors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phenylephrine; Potassium; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway.
    European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Blotting, Western; Carotid Arteries; Cell Adhesion; Cell Line; Chemokine CCL2; Cyclic GMP; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Gene Expression; Guanylate Cyclase; Humans; Hydrolyzable Tannins; In Vitro Techniques; Intercellular Adhesion Molecule-1; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Paeonia; Plant Bark; Plant Roots; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Necrosis Factor-alpha; U937 Cells; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents

2005
Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: Analgesia; Animals; Blood Glucose; Body Weight; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Streptozocin; Sulfones; Time Factors

2005
Relaxant effect of sildenafil in the rabbit basilar artery.
    Vascular pharmacology, 2006, Volume: 44, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Basilar Artery; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rabbits; Signal Transduction; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents

2006
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Tadalafil; Tetrodotoxin

2006
Analysis of the mechanisms underlying the vasorelaxant action of angiotensin II in the isolated rat carotid.
    Life sciences, 2006, May-01, Volume: 78, Issue:23

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peptide Fragments; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Saralasin; Vasoconstrictor Agents; Vasodilation

2006
Vasorelaxing effect of BAY 41-2272 in rat basilar artery: involvement of cGMP-dependent and independent mechanisms.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:3

    Topics: Animals; Basilar Artery; Brain Stem; Calcium Chloride; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Ouabain; Oxadiazoles; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2006
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Diazoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indazoles; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Okadaic Acid; Oxadiazoles; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Spinal Nerves; Stereoisomerism; Time Factors; Vasodilator Agents

2006
Mechanisms underlying the vasorelaxing effects of butylidenephthalide, an active constituent of Ligusticum chuanxiong, in rat isolated aorta.
    European journal of pharmacology, 2006, May-10, Volume: 537, Issue:1-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Ligusticum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Phthalic Anhydrides; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents

2006
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats.
    European journal of pharmacology, 2006, May-10, Volume: 537, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Spinal Cord; Tryptamines; Vasoconstriction

2006
Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta.
    Life sciences, 2006, Aug-08, Volume: 79, Issue:11

    Topics: Animals; Aorta, Thoracic; Atropine; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Lamiaceae; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Plant Extracts; Quinoxalines; Rats; Rats, Wistar; Triterpenes; Ursolic Acid; Vasodilation; Vasodilator Agents

2006
Injection of l-glutamate into medial prefrontal cortex induces cardiovascular responses through NMDA receptor - nitric oxide in rat.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: Animals; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2006
Evidence for a role of inducible nitric oxide synthase in gastric relaxation of mdx mice.
    Neurogastroenterology and motility, 2006, Volume: 18, Issue:6

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred mdx; Muscle Relaxation; Muscle, Smooth; Muscular Dystrophy, Duchenne; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Vasoactive Intestinal Peptide

2006
Endothelium-independent flow-induced dilation in the mouse carotid artery.
    Journal of vascular research, 2006, Volume: 43, Issue:4

    Topics: Acetylcholine; Animals; Blood Flow Velocity; Carotid Arteries; Cyclooxygenase Inhibitors; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines; Vasodilation; Vasodilator Agents

2006
Investigation of the mechanism for the relaxation of rat duodenum mediated via M1 muscarinic receptors.
    Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bicuculline; Dose-Response Relationship, Drug; Duodenum; Elapid Venoms; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Oxadiazoles; Penicillamine; Pirenzepine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Suramin

2006
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:4

    Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil

2006
Activation of the cGMP signaling pathway is essential in delaying oocyte aging in diabetes mellitus.
    Biochemistry, 2006, Sep-26, Volume: 45, Issue:38

    Topics: Animals; Cellular Senescence; Cyclic GMP; Cytoplasmic Granules; Diabetes Mellitus; Female; Mice; Microtubules; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oocytes; Oxadiazoles; Oxyhemoglobins; Protein Kinase Inhibitors; Quinoxalines; Signal Transduction; Zona Pellucida

2006
The suppressant effect of GEA3162 on spontaneous serotonin release from human colonic mucosa in vitro.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Colon; Electrochemistry; Enzyme Inhibitors; Gastrointestinal Hormones; Guanylate Cyclase; Hydroxyindoleacetic Acid; Intestinal Mucosa; Natriuretic Peptides; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Peroxynitrous Acid; Quinoxalines; Serotonin; Triazoles

2006
NANC inhibitory neuromuscular transmission in the hamster distal colon.
    Pharmacological research, 2006, Volume: 54, Issue:6

    Topics: Adenosine Triphosphate; Animals; Apamin; Autonomic Nervous System; Colon; Cricetinae; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Male; Membrane Potentials; Mesocricetus; Muscle, Smooth; Neuroeffector Junction; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Purinergic Antagonists; Quinoxalines; Receptors, Purinergic; Suramin; Synaptic Transmission; Thionucleotides; Triazines

2006
Activation of nitric oxide signaling pathway mediates hypotensive effect of Muntingia calabura L. (Tiliaceae) leaf extract.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:5

    Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Injections, Intravenous; Magnoliopsida; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Plant Extracts; Plant Leaves; Plants, Medicinal; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Tiliaceae; Water

2006
Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:1

    Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents

2007
Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition.
    Cardiovascular research, 2007, Jul-15, Volume: 75, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Celecoxib; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Perfusion; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Purinones; Pyrazoles; Quinoxalines; Rats; Regional Blood Flow; Signal Transduction; Sildenafil Citrate; Sulfonamides; Sulfones; Vasodilator Agents

2007
Role of NO/cGMP/KATP pathway in antinociceptive effect of sildenafil in zymosan writhing response in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Piperazines; Potassium Channels; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones; Zymosan

2007
Vasorelaxant effects of icariin on isolated canine coronary artery.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Dinoprost; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium, Vascular; Enzyme Inhibitors; Female; Flavonoids; Glyburide; Indomethacin; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxadiazoles; Oxytocics; Potassium Channel Blockers; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetraethylammonium; Vasodilation

2007
Nitric oxide-mediated nonadrenergic noncholinergic relaxation of piglet pulmonary arteries decreases with postnatal age.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:1

    Topics: Animals; Animals, Newborn; Blotting, Western; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Myography; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxadiazoles; Pulmonary Artery; Quinoxalines; Swine; Tetrodotoxin; Vasodilation

2007
Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: correlated with NO-cGMP signaling pathway.
    European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiovascular Agents; Cell Proliferation; Cell Size; Cells, Cultured; Cyclic GMP; Fibroblasts; Intracellular Space; L-Lactate Dehydrogenase; Male; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes

2007
In vivo assessment of safety and mechanisms underlying in vitro relaxation induced by Mikania laevigata Schultz Bip. ex Baker in the rat trachea.
    Journal of ethnopharmacology, 2007, Jul-25, Volume: 112, Issue:3

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Brazil; Coumarins; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glyburide; In Vitro Techniques; Male; Mice; Mikania; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Oxadiazoles; Plant Extracts; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Toxicity Tests, Acute; Toxicity Tests, Chronic; Trachea

2007
Guanylate cyclase activators influence reactivity of human mesenteric superior arteries retrieved and preserved in the same conditions as transplanted kidneys.
    Transplantation proceedings, 2007, Volume: 39, Issue:5

    Topics: Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indazoles; Kidney Transplantation; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Organ Preservation; Oxadiazoles; Platelet Aggregation Inhibitors; Quinoxalines; Retrospective Studies; Vasodilation; Vasodilator Agents

2007
Intracerebroventricular administration of nitric oxide-sensitive guanylyl cyclase inhibitors induces catalepsy in mice.
    Psychopharmacology, 2007, Volume: 194, Issue:2

    Topics: Animals; Arginine; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors

2007
N(G)-nitro-L-arginine methyl ester, but not methylene blue, attenuates anaphylactic hypotension in anesthetized mice.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:3

    Topics: Anaphylaxis; Anesthesia; Animals; Blood Pressure; Enzyme Inhibitors; Guanylate Cyclase; Hypertension; Liver Circulation; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ovalbumin; Oxadiazoles; Quinoxalines

2007
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 148, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors

2007
Functional role of the soluble guanylyl cyclase alpha(1) subunit in vascular smooth muscle relaxation.
    Cardiovascular research, 2007, Oct-01, Volume: 76, Issue:1

    Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Female; Guanylate Cyclase; In Vitro Techniques; Indazoles; Isoenzymes; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Vasodilator Agents

2007
Nitric oxide attenuates endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 in vascular smooth muscle cells by a cGMP-dependent pathway.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Focal Adhesion Kinase 2; Guanylate Cyclase; Hypertrophy; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Soluble Guanylyl Cyclase

2007
Anxiolytic effects induced by inhibition of the nitric oxide-cGMP pathway in the rat dorsal hippocampus.
    Psychopharmacology, 2007, Volume: 195, Issue:2

    Topics: Analysis of Variance; Animals; Anxiety; Cyclic GMP; Dentate Gyrus; Dose-Response Relationship, Drug; Guanylate Cyclase; Hippocampus; Indazoles; Male; Maze Learning; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Punishment; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2007
Resveratrol, a component of red wine, elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:9

    Topics: Animals; Antioxidants; Arterioles; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavonoids; Guanylate Cyclase; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Resveratrol; Retinal Artery; Stilbenes; Swine; Vasodilation; Vasodilator Agents; Video Recording; Wine

2007
Nitric oxide signaling in the medial prefrontal cortex is involved in the biochemical and behavioral effects of phencyclidine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cyclic GMP; Double-Blind Method; Electrodes, Implanted; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Mice; Microdialysis; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phencyclidine; Prefrontal Cortex; Quinoxalines; Radioimmunoassay; Reflex, Startle; Signal Transduction

2008
Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Autonomic Denervation; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Oxyhemoglobins; Phenylephrine; Quinoxalines; Rats

2007
Calcium/calmodulin-dependent kinase II mediates NO-elicited PKG activation to participate in spinal reflex potentiation in anesthetized rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2

    Topics: Action Potentials; Anesthesia; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic GMP-Dependent Protein Kinases; Electromyography; Enzyme Inhibitors; Hyperalgesia; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Reflex; Signal Transduction; Spinal Cord

2008
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
    British journal of pharmacology, 2008, Volume: 153, Issue:4

    Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones

2008
Antihypertensive effect of biotin in stroke-prone spontaneously hypertensive rats.
    The British journal of nutrition, 2008, Volume: 99, Issue:4

    Topics: Animals; Biotin; Coronary Vessels; Genetic Predisposition to Disease; Glucose Tolerance Test; Guanylate Cyclase; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Time; Vitamins

2008
Two autocrine pathways to regulate cyclic GMP synthesis in cultured human retinal pigment epithelial cells.
    Ophthalmic research, 2008, Volume: 40, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Autocrine Communication; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Guanylate Cyclase; Humans; Immunohistochemistry; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Oxadiazoles; Phosphodiesterase Inhibitors; Pigment Epithelium of Eye; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2008
Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta.
    British journal of pharmacology, 2008, Volume: 154, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta, Thoracic; Dinoprost; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Potassium; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Calcium Exchanger; Thiourea; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2008
Involvement of soluble guanylate cyclase alpha(1) and alpha(2), and SK(Ca) channels in NANC relaxation of mouse distal colon.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Animals; Apamin; Blotting, Western; Colon; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanylate Cyclase; Male; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Potassium Channel Blockers; Protein Subunits; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Small-Conductance Calcium-Activated Potassium Channels; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide

2008
Nitric oxide mediates stretch-induced Ca2+ release via activation of phosphatidylinositol 3-kinase-Akt pathway in smooth muscle.
    PloS one, 2008, Jun-25, Volume: 3, Issue:6

    Topics: Androstadienes; Animals; Calcium; Enzyme Activation; Enzyme Inhibitors; Mice; Mice, Knockout; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinoxalines; Urothelium; Wortmannin

2008
Calcitonin gene-related peptide suppresses pacemaker currents by nitric oxide/cGMP-dependent activation of ATP-sensitive K(+) channels in cultured interstitial cells of Cajal from the mouse small intestine.
    Molecules and cells, 2008, Aug-31, Volume: 26, Issue:2

    Topics: Adenine; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Cyclic GMP; Female; Guanylate Cyclase; Intestine, Small; KATP Channels; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Quinoxalines

2008
Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2.
    Molecular carcinogenesis, 2009, Volume: 48, Issue:3

    Topics: Adenocarcinoma; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cell Survival; Cyclic GMP; Enzyme Inhibitors; Fluorescent Antibody Technique; Grape Seed Extract; Guanylate Cyclase; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Plant Extracts; Proanthocyanidins; Quinoxalines; Receptors, Cell Surface; Signal Transduction; Tumor Cells, Cultured; Vitis

2009
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines

2008
Pre-conditioning induced by carbon monoxide provides neuronal protection against apoptosis.
    Journal of neurochemistry, 2008, Volume: 107, Issue:2

    Topics: Animals; Animals, Newborn; Apoptosis; Carbon Monoxide; Cells, Cultured; Cerebellum; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hydroxy Acids; Metalloporphyrins; Mice; Neurons; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxidative Stress; Quinoxalines; Reactive Oxygen Species; tert-Butylhydroperoxide; Time Factors

2008
EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase.
    Biochemical and biophysical research communications, 2008, Oct-10, Volume: 375, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinoma; Catechin; Cell Line, Tumor; Cell Movement; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Mammary Neoplasms, Animal; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen Oxides; Oxadiazoles; Quinoxalines

2008
Fluvastatin reduces pulmonary vein spontaneous activity through nitric oxide pathway.
    Journal of cardiovascular electrophysiology, 2009, Volume: 20, Issue:2

    Topics: Action Potentials; Androstadienes; Animals; Atrial Fibrillation; Blotting, Western; Electrophysiology; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Heart Atria; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Indoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Oxadiazoles; Phosphatidylinositol 3-Kinases; Pulmonary Veins; Quinoxalines; Rabbits; Signal Transduction; Wortmannin

2009
Inhibition by lithium of the nitrergic relaxation of rat anococcygeus muscle.
    Nitric oxide : biology and chemistry, 2009, Volume: 20, Issue:1

    Topics: Analysis of Variance; Animals; Arginine; Electric Stimulation; Lithium Chloride; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2009
Sodium azide induced neuronal damage in vitro: evidence for non-apoptotic cell death.
    Neurochemical research, 2009, Volume: 34, Issue:5

    Topics: Acetylcarnitine; Animals; Antioxidants; Apoptosis; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Dizocilpine Maleate; Guanylate Cyclase; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Azide

2009
Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Animals; Carbolines; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanylate Cyclase; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitroglycerin; Oxadiazoles; Penile Erection; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents

2009
Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats.
    Journal of neuroscience research, 2009, May-15, Volume: 87, Issue:7

    Topics: Animals; Arginine; Baroreflex; Benzoates; Blood Pressure; Cardiac Output; Cholinergic Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Imidazoles; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroprusside; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Tropanes

2009
Epigallocatechin-3-gallate relaxes the isolated bovine ophthalmic artery: involvement of phosphoinositide 3-kinase-Akt-nitric oxide/cGMP signalling pathway.
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Androstadienes; Animals; Catechin; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Ophthalmic Artery; Oxadiazoles; Penicillamine; Peptides; Phosphatidylinositols; Proto-Oncogene Proteins c-akt; Quinoxalines; Serotonin; Signal Transduction; Vasodilation; Wortmannin

2009
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
    European journal of pharmacology, 2009, May-21, Volume: 610, Issue:1-3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors

2009
Endothelium-derived nitric oxide contributes to the vasorelaxant response induced by mesoionic 2-(4-chlorophenyl)-3-methyl-4-(4-methoxyphenyl)-1;3-thiazolium-5-thyolate (CMMTT) in rats.
    Journal of pharmacological sciences, 2009, Volume: 110, Issue:1

    Topics: Animals; Biological Factors; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Thiazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2009
Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Exonucleases; Guanylate Cyclase; Imidazoles; Male; Mice; Mice, Inbred ICR; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Oxadiazoles; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Recombinant Proteins; Signal Transduction; Triazines

2009
Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzophenanthridines; Body Weight; Calcium; Chick Embryo; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Femoral Artery; Hypoxia; NG-Nitroarginine Methyl Ester; Oxadiazoles; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Quinoxalines; rho-Associated Kinases; Vasoconstriction

2010
Propyretic role of the locus coeruleus nitric oxide pathway.
    Experimental physiology, 2010, Volume: 95, Issue:6

    Topics: Animals; Cyclic GMP; Endotoxins; Fever; Guanylate Cyclase; Locus Coeruleus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2010
Water extract of Zanthoxylum piperitum induces vascular relaxation via endothelium-dependent NO-cGMP signaling.
    Journal of ethnopharmacology, 2010, May-27, Volume: 129, Issue:2

    Topics: Androstadienes; Animals; Boron Compounds; Calcium; Calcium Channels; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Gadolinium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Plant Extracts; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thapsigargin; Vasoconstriction; Vasodilator Agents; Wortmannin; Zanthoxylum

2010
Differential regulation of vasoactive intestinal peptide (VIP) in the dentate gyrus and hippocampus via the NO-cGMP pathway following kainic acid-induced seizure in the rat.
    Journal of molecular neuroscience : MN, 2010, Volume: 42, Issue:3

    Topics: Animals; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Indazoles; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide

2010
A soluble guanylate cyclase mediates negative signaling by ammonium on expression of nitrate reductase in Chlamydomonas.
    The Plant cell, 2010, Volume: 22, Issue:5

    Topics: Aminoquinolines; Arabidopsis; Arabidopsis Proteins; Calcium; Chlamydomonas reinhardtii; Cyclic GMP; Cyclic N-Oxides; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Imidazoles; Models, Biological; Molecular Sequence Data; Mutation; NG-Nitroarginine Methyl Ester; Nitrate Reductase; Nitric Oxide; Nitrogen; Oxadiazoles; Quaternary Ammonium Compounds; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Transcription, Genetic

2010
Effects induced by inhibitors of the phosphatidylinositol 3-kinase/Akt and nitric oxide synthase/guanylyl cyclase pathways on the isometric contraction in rat aorta: a comparative study.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:3

    Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Chromones; Endothelium, Vascular; Guanylate Cyclase; Isometric Contraction; Male; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Phenylephrine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Potassium; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin

2011
Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.
    European journal of pharmacology, 2010, Oct-25, Volume: 645, Issue:1-3

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Trachea

2010
Nitric oxide in the control of luminescence from lantern shark (Etmopterus spinax) photophores.
    The Journal of experimental biology, 2010, Volume: 213, Issue:Pt 17

    Topics: Animal Structures; Animals; Cyclic GMP; Embryo, Nonmammalian; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Immunohistochemistry; Luminescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Quinoxalines; Sharks; Signal Transduction; Spectrum Analysis

2010
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane

2010
Inhibition of hypoxic pulmonary vasoconstriction of rats by carbon monoxide.
    Journal of Korean medical science, 2010, Volume: 25, Issue:10

    Topics: Animals; Carbon Monoxide; Guanylate Cyclase; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rats; Tetraethylammonium; Vasoconstriction

2010
Role of the spinal cord NO/cGMP pathway in the control of arterial pressure and heart rate.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Blood Pressure; Cyclic GMP; Dimethyl Sulfoxide; Heart Rate; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stereoisomerism; Sympathetic Nervous System

2011
Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.
    The Journal of veterinary medical science, 2011, Volume: 73, Issue:4

    Topics: Animals; Cricetinae; Cyclic GMP; Ileum; Male; Membrane Potentials; Mesocricetus; Myocytes, Smooth Muscle; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Substance P; Tachykinins

2011
Neuroprotective mechanisms of minocycline against sphingomyelinase/ceramide toxicity: Roles of Bcl-2 and thioredoxin.
    Free radical biology & medicine, 2011, Mar-15, Volume: 50, Issue:6

    Topics: Animals; Blotting, Western; Carbazoles; Cells, Cultured; Ceramides; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dinitrochlorobenzene; Genes, bcl-2; Minocycline; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingomyelin Phosphodiesterase; Thioredoxins

2011
Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoates; Biphenyl Compounds; Guanylate Cyclase; Heme; Hydrocarbons, Fluorinated; Hypertension, Pulmonary; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2011
Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of corpus cavernosum from the South American rattlesnake Crotalus durissus terrificus.
    The journal of sexual medicine, 2011, Volume: 8, Issue:6

    Topics: Acetylcholine; Animals; Callithrix; Carbolines; Crotalus; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Microscopy, Electron, Scanning; NG-Nitroarginine Methyl Ester; Nitrergic Neurons; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Penis; Pyrazoles; Pyridines; Quinoxalines; Sodium Channel Blockers; Sodium Channels; Tadalafil; Tetrodotoxin; Vasodilator Agents

2011
Developmental changes in mesenteric artery reactivity in embryonic and newly hatched chicks.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2011, Volume: 181, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Animals, Newborn; Body Weight; Chick Embryo; Chickens; Colforsin; Embryonic Development; Endothelin-1; Enzyme Inhibitors; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Oxadiazoles; Potassium Chloride; Quinoxalines; Vasoconstriction; Vasodilation

2011
The role of capillarisin from Artemisia capillaris on penile erection.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:6

    Topics: Animals; Artemisia; Chromones; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Evaluation, Preclinical; Ethanol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Phenylephrine; Phosphodiesterase 5 Inhibitors; Plant Extracts; Quinoxalines; Rabbits; Radioimmunoassay; Signal Transduction

2012
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation of vascular smooth muscle cells: involvement of NO/cGMP/PKG pathway.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:7

    Topics: Animals; Becaplermin; Carbazoles; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Glucosides; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polygonum; Proto-Oncogene Proteins c-sis; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes

2012
Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide.
    American journal of physiology. Heart and circulatory physiology, 2012, Mar-01, Volume: 302, Issue:5

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Heart; Microvessels; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Papillary Muscles; Peptide Fragments; Quinoxalines; Rats; Rats, Wistar; Troponin I

2012
Endothelial dysfunction in the human umbilical artery due to preeclampsia can be prevented by sildenafil.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperazines; Pre-Eclampsia; Pregnancy; Purines; Quinoxalines; Sildenafil Citrate; Sulfones; Umbilical Arteries; Vasodilation; Vasodilator Agents; Young Adult

2012
Alpha2C-adrenoceptors play a prominent role in sympathetic constriction of porcine pulmonary arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Agonists; Enzyme Inhibitors; HeLa Cells; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Pulmonary Artery; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine; Vasoconstriction

2012
Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats.
    European journal of pharmacology, 2012, Jun-05, Volume: 684, Issue:1-3

    Topics: Animals; Biguanides; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Spermidine

2012
Mechanism of relaxation and interaction with nitric oxide of the soluble guanylate cyclase stimulator BAY 41-2272 in mouse gastric fundus and colon.
    European journal of pharmacology, 2012, Jul-05, Volume: 686, Issue:1-3

    Topics: Animals; Colon; Cyclic GMP; Enzyme Inhibitors; Gastric Fundus; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Male; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2012
Pendrin protein abundance in the kidney is regulated by nitric oxide and cAMP.
    American journal of physiology. Renal physiology, 2012, Sep-15, Volume: 303, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Anion Transport Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Imidazoles; Kidney Tubules, Collecting; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroso Compounds; Oxadiazoles; Quinoxalines; Sulfate Transporters; Triazines

2012
Essential role of nitric oxide in acute ischemic preconditioning: S-nitros(yl)ation versus sGC/cGMP/PKG signaling?
    Free radical biology & medicine, 2013, Volume: 54

    Topics: Animals; Ascorbic Acid; Carbazoles; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Guanylate Cyclase; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrosation; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Reperfusion Injury; Signal Transduction

2013
In vivo regulation of renal expression of (pro)renin receptor by a low-sodium diet.
    American journal of physiology. Renal physiology, 2012, Dec-15, Volume: 303, Issue:12

    Topics: Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diet, Sodium-Restricted; Enzyme Inhibitors; Kidney; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Oxadiazoles; Prorenin Receptor; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Signal Transduction

2012
Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: implications for breast cancer.
    Free radical biology & medicine, 2013, Volume: 57

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex IV; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Guanylate Cyclase; Humans; Hydrogen Peroxide; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Oxygen Consumption; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Quinoxalines

2013
Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase.
    Experimental & molecular medicine, 2012, Dec-31, Volume: 44, Issue:12

    Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Phenylephrine; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Propanols; Quinoxalines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilation

2012
The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:12

    Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Lignans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Piper; Quinoxalines; Rats; Rats, Wistar; Vasodilation

2013
Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95 Suppl 12

    Topics: Analysis of Variance; Animals; Aorta; Barium Compounds; Calcium Chloride; Chlorides; Endothelium, Vascular; Glyburide; Indomethacin; Male; Methoxamine; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasodilation; Vasodilator Agents; Xanthones

2012
Alteration of neuromuscular transmissions in the hamster colon following the resolution of TNBS-induced colitis.
    The journal of physiological sciences : JPS, 2013, Volume: 63, Issue:4

    Topics: Animals; Colitis; Colon; Cricetinae; Electric Stimulation; Male; Mesocricetus; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peristalsis; Quinoxalines; Receptors, Tachykinin; Synaptic Transmission; Trinitrobenzenesulfonic Acid

2013
The sGC activator BAY 60-2770 has potent erectile activity in the rat.
    American journal of physiology. Heart and circulatory physiology, 2013, Jun-15, Volume: 304, Issue:12

    Topics: Animals; Benzoates; Biphenyl Compounds; Blood Pressure; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydrocarbons, Fluorinated; Injections; Male; Nerve Crush; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Penile Erection; Penis; Peripheral Nerves; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2013
Imatinib mesylate (Gleevec) induces human corpus cavernosum relaxation by inhibiting receptor tyrosine kinases (RTKs): identification of new RTK targets.
    Urology, 2013, Volume: 82, Issue:3

    Topics: Adult; Aged; Apamin; Benzamides; Enzyme Activation; Erectile Dysfunction; Humans; Imatinib Mesylate; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Oxadiazoles; Penis; Phosphorylation; Piperazines; Potassium Channel Blockers; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Quinoxalines; Receptor Protein-Tyrosine Kinases; Tetraethylammonium

2013
Mechanisms underlying the antinociceptive effect of mangiferin in the formalin test.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Analgesics; Animals; Capsaicin; Formaldehyde; Glyburide; Male; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Nociception; Quinoxalines; Rats; Rats, Wistar; Serotonin; Xanthones

2013
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.
    Life sciences, 2013, Oct-17, Volume: 93, Issue:17

    Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds

2013
Ovariectomy increases the participation of hyperpolarizing mechanisms in the relaxation of rat aorta.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Acetylcholine; Animals; Aorta; Catalase; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Gene Expression; Guanylate Cyclase; Hydrogen Peroxide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ovariectomy; Oxadiazoles; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Culture Techniques; Vasodilation; Vasodilator Agents

2013
Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat.
    American journal of physiology. Heart and circulatory physiology, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Acetylcholine; Animals; Arterial Pressure; Bradykinin; Enzyme Inhibitors; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; TRPV Cation Channels; Vasodilation; Vasodilator Agents

2014
Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics.
    Microcirculation (New York, N.Y. : 1994), 2014, Volume: 21, Issue:7

    Topics: Animals; Cimetidine; Endothelium, Lymphatic; Guanylate Cyclase; Histamine H1 Antagonists; Histamine H2 Antagonists; Lymphatic Vessels; Male; Mesentery; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Pyrilamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Histamine H1; Receptors, Histamine H2; Soluble Guanylyl Cyclase

2014
Involvement of nitric oxide and ATP-sensitive potassium channels in the peripheral antinoceptive action of a tramadol-dexketoprofen combination in the formalin test.
    Drug development research, 2014, Volume: 75, Issue:7

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Glyburide; KATP Channels; Ketoprofen; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain Measurement; Quinoxalines; Tramadol; Tromethamine

2014
Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells.
    Experimental eye research, 2014, Volume: 128

    Topics: Acidosis; Animals; Arterioles; Benzopyrans; Bradykinin; Carbonic Anhydrase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Lactates; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasodilation

2014
A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries.
    Pharmacological research, 2014, Volume: 90

    Topics: Animals; Bradykinin; Carbenoxolone; Catalase; Colforsin; Coronary Vessels; Female; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Ouabain; Oxadiazoles; Peptides; Polyethylene Glycols; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents; Vasodilation; Verapamil

2014
Linalool elicits vasorelaxation of mouse aortae through activation of guanylyl cyclase and K(+) channels.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:5

    Topics: Acyclic Monoterpenes; Animals; Aorta; Calcium; Calcium Chloride; Dinoprost; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Activation; Guanylate Cyclase; Male; Mice; Monoterpenes; NG-Nitroarginine Methyl Ester; Oxadiazoles; Potassium Channels; Quinoxalines; Tetraethylammonium; Vasodilation; Vasodilator Agents

2015
Neuroprotective effect of noscapine on cerebral oxygen-glucose deprivation injury.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:2

    Topics: Animals; Brain Ischemia; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glucose; Hypoxia; Mice; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide; Noscapine; Primary Cell Culture; Quinoxalines; Thapsigargin

2015
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-08, Volume: 35, Issue:14

    Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Cortex; Channelopathies; Cortical Synchronization; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Transgenic; Mutation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Potassium Channel Blockers; Pyridines; Quinoxalines; Vibrissae

2015
5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.
    Vascular pharmacology, 2015, Volume: 72

    Topics: Animals; Blood Pressure; Heart Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sympathetic Nervous System; Synaptic Transmission; Tryptamines

2015
Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.
    Psychopharmacology, 2016, Volume: 233, Issue:3

    Topics: Animals; Carbazoles; Cell Adhesion Molecules; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 2; Dose-Response Relationship, Drug; Guanylate Cyclase; Imidazoles; Male; Memory; Mice, Inbred ICR; Microfilament Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoproteins; Protein Kinase Inhibitors; Quinoxalines; Recognition, Psychology; Triazines

2016
Effects of NO Donors and Inhibitors of NO Synthase and Guanylate Cyclase on the Acquisition of a Conditioned Defense Food Aversion Response in Edible Snails.
    Bulletin of experimental biology and medicine, 2016, Volume: 160, Issue:4

    Topics: Animals; Conditioning, Psychological; Enzyme Inhibitors; Guanylate Cyclase; Iron; Learning; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Quinoxalines; Shellfish; Snails

2016
In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat.
    Journal of pharmacological sciences, 2016, Volume: 131, Issue:4

    Topics: Animals; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Glyburide; In Vitro Techniques; KATP Channels; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nicorandil; Oxadiazoles; Peptides; Pinacidil; Potassium; Quinoxalines; Rats

2016
Activation of Secretagogue Independent Gastric Acid Secretion via Endothelial Nitric Oxide Synthase Stimulation in Rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 44, Issue:4

    Topics: Animals; Arginine; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxadiazoles; Parietal Cells, Gastric; Quinoxalines; Rats; Rats, Sprague-Dawley

2017
Heat shock protein-27 and sex-selective regulation of muscarinic and proteinase-activated receptor 2-mediated vasodilatation: differential sensitivity to endothelial NOS inhibition.
    British journal of pharmacology, 2018, Volume: 175, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; HSP27 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxadiazoles; Quinoxalines; Receptor, PAR-2; Receptors, Muscarinic; Structure-Activity Relationship; Vasodilation

2018
Endothelial modulation of a nitric oxide donor complex-induced relaxation in normotensive and spontaneously hypertensive rats.
    Life sciences, 2018, May-15, Volume: 201

    Topics: Animals; Coordination Complexes; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanylate Cyclase; Male; Mesenteric Arteries; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxadiazoles; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Inbred SHR; Ruthenium; Vascular Resistance; Vasodilation

2018
Kaempferol-induces vasorelaxation via endothelium-independent pathways in rat isolated pulmonary artery.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: Animals; Apamin; Barium Compounds; Calcium Chloride; Chlorides; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Fulvestrant; Glyburide; In Vitro Techniques; Indomethacin; Isoquinolines; Kaempferols; Male; Morpholines; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peptides; Potassium; Pulmonary Artery; Pyrroles; Quinoxalines; Rats; Sulfonamides; Tetraethylammonium; Vasodilation; Vasodilator Agents

2018
Role of Carbon Monoxide in the Mechanisms of Action of Extracellular ATP on Contractile Activity of Vascular Smooth Muscle Cells.
    Bulletin of experimental biology and medicine, 2019, Volume: 167, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Carbon Monoxide; Cells, Cultured; Endothelium; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Organometallic Compounds; Oxadiazoles; Phenylephrine; Protoporphyrins; Purinergic P2X Receptor Agonists; Purinergic P2Y Receptor Agonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P2X; Receptors, Purinergic P2Y

2019
Perivascular adipose tissue phenotype and sepsis vascular dysfunction: Differential contribution of NO, ROS and beta 3-adrenergic receptor.
    Life sciences, 2020, Aug-01, Volume: 254

    Topics: Acetophenones; Adipose Tissue; Adrenergic beta-3 Receptor Agonists; Animals; Aorta; Cyclic N-Oxides; Female; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Phenotype; Quinoxalines; Rats; Reactive Oxygen Species; Receptors, Adrenergic, beta-3; Sepsis; Spin Labels; Vasoconstriction

2020
Antihypertensive and vasorelaxant effect of leucodin and achillin isolated from Achillea millefolium through calcium channel blockade and NO production: In vivo, functional ex vivo and in silico studies.
    Journal of ethnopharmacology, 2021, Jun-12, Volume: 273

    Topics: Achillea; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Computer Simulation; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Plant Extracts; Quinoxalines; Rats, Inbred SHR; Rats, Wistar; Sesquiterpenes; Vasodilator Agents

2021