quinoxalines has been researched along with naloxone in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 14 (43.75) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 4 (12.50) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Slavik, KJ; Szilagyi, JE | 2 |
| Pinnock, RD | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Trzebski, A; Yoshimura, M | 1 |
| Harrison, NL; Lambert, NA; Teyler, TJ | 1 |
| Christie, MJ; Miyake, M; North, RA | 1 |
| Lester, BR; Sun, Z; Wilcox, GL; Wu, HH | 1 |
| Birnbaum, AK; Law, PY; Wilcox, GL; Wotta, DR | 1 |
| Calvo, P; Fernández-López, A; Gómez, T; Revilla, V; Soria, C | 1 |
| Nicoll, RA; Weisskopf, MG; Zalutsky, RA | 1 |
| Cappendijk, SL; de Vries, R; Dzoljic, MR | 1 |
| Beani, L; Bianchi, C; Borea, PA; Simonato, M; Varani, K | 1 |
| Keana, JF; Kwon, IS; Lutfy, K; Marek, P; Sadowski, B; Weber, E | 1 |
| Chieng, B; Christie, MJ; Connor, M | 1 |
| Gruol, DL; Netzeband, JG; Parsons, KL; Przewlocki, R; Siggins, GR; Sweeney, DD; Trotter, C | 1 |
| Hall, SR; Jhamandas, K; Milne, B; Sullivan, ME | 1 |
| Sztajnbok, J | 1 |
| García-Barrado, MJ; Iglesias-Osma, MC; Martín, M; Moratinos, J; Rodríguez, R | 1 |
| Kratzer, U; Schmidt, WJ | 1 |
| Wang, HL; Wang, HS; Wu, WR; Xiang, XH; Zhao, Y | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J | 1 |
| Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L | 1 |
| Cao, DY; Guo, Y; Wang, HL; Wang, HS; Wu, WR; Xiang, XH; Zhao, Y | 1 |
| Aase, DM; Atkinson, DM; Gewirtz, JC; Harris, AC | 1 |
| Brock, SC; Tonussi, CR | 1 |
| Cunha, FQ; Duarte, DB; Ferrari, LF; Ferreira, SH; Funez, MI; Lorenzetti, BB; Parada, CA; Sachs, D | 1 |
| Huntington, N; Lai Becker, M; Woolf, AD | 1 |
| Castro, RR; Cunha, FQ; Girão, VC; Leite, AC; Leite, AK; Rocha, FA; Silva, FS | 1 |
| Cervantes-Durán, C; Espinosa de los Monteros-Zuñiga, A; Godínez-Chaparro, B; Izquierdo, T; Lozada, MC | 1 |
| Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Quiñonez-Bastidas, GN; Rocha-González, HI | 1 |
| Asatryan, A; Geoffroy, P; Kort, J; Kosloski, MP; Liu, W; Zhao, W | 1 |
| Chambers, A; Cumpston, KL; Kershner, E; Tobarran, N; Wills, BK | 1 |
1 trial(s) available for quinoxalines and naloxone
| Article | Year |
|---|---|
No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir.
Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cyclopropanes; Drug Interactions; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Male; Methadone; Middle Aged; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Proline; Protease Inhibitors; Pyrrolidines; Quinoxalines; Sulfonamides; Surveys and Questionnaires; Young Adult | 2017 |
31 other study(ies) available for quinoxalines and naloxone
| Article | Year |
|---|---|
Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors.
Topics: Animals; Atropine; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Methacholine Chloride; Naloxone; Phentolamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Fast inhibitory postsynaptic potentials and responses to inhibitory amino acids of sympathetic preganglionic neurons in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Bicuculline; Cats; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glycine; Membrane Potentials; Naloxone; Neurons; Phentolamine; Quinoxalines; Spinal Cord; Strychnine; Synapses | 1992 |
Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Barium; Bicuculline; Dendrites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Ion Channel Gating; Naloxone; Nerve Endings; Potassium Channels; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Single potassium channels opened by opioids in rat locus ceruleus neurons.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Brimonidine Tartrate; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Electric Conductivity; Endorphins; Enkephalin, Methionine; Locus Coeruleus; Membrane Potentials; Naloxone; Neurons; Potassium Channels; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Receptors, Somatostatin; Somatostatin | 1989 |
Antinociception following implantation of mouse B16 melanoma cells in mouse and rat spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Catecholamines; Cell Transplantation; Desipramine; Dioxanes; Idazoxan; Injections, Spinal; Male; Melanoma, Experimental; Mice; Mice, Inbred ICR; Morphine; Naloxone; Neoplasm Transplantation; Nociceptors; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Substance P; Transplantation, Heterotopic | 1994 |
Functional expression of adrenergic and opioid receptors in Xenopus oocytes: interaction between alpha 2- and beta 2-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; Brimonidine Tartrate; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Dose-Response Relationship, Drug; Isoproterenol; Models, Biological; Naloxone; Oocytes; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Receptors, Opioid; RNA, Messenger; Xenopus laevis | 1995 |
Effect of morphine and abstinence syndrome on [3H]bromoxidine binding to alpha 2-adrenoceptors in rat brain.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Brain; Brimonidine Tartrate; Drug Implants; Hippocampus; Male; Mesencephalon; Morphine; Morphine Dependence; Naloxone; Occipital Lobe; Organ Specificity; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reference Values; Substance Withdrawal Syndrome; Superior Colliculi; Tritium | 1994 |
The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Naloxone; Nerve Fibers; Pyramidal Tracts; Quinoxalines; Receptors, Opioid, kappa; Synapses | 1993 |
Naloxone-induced potentiation of cardiac alpha-2 adrenoceptor-mediated depression of neurogenic tachycardia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Heart; Male; Myocardium; Naloxone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Tachycardia | 1993 |
Excitatory amino acid receptor antagonists and naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Mice; Morphine Dependence; Naloxone; Quinoxalines; Receptors, Amino Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substance Withdrawal Syndrome | 1993 |
Changes in [3H]-UK 14304 binding to alpha 2-adrenoceptors in morphine-dependent guinea-pigs.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Synaptosomes; Tritium | 1995 |
Differential sensitivity of mice bred for stress-induced analgesia to morphine and ACEA-1011 in the formalin test.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Quinoxalines; Stress, Psychological; Swimming | 1996 |
The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.
Topics: Animals; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Naloxone; Narcotics; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Peptides; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 1996 |
Opioid enhancement of calcium oscillations and burst events involving NMDA receptors and L-type calcium channels in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Hippocampus; Kinetics; Membrane Potentials; Naloxone; Neurons; Nimodipine; Oscillometry; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Tetrodotoxin; Time Factors | 1999 |
Suppression of acute and chronic opioid withdrawal by a selective soluble guanylyl cyclase inhibitor.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acids; Guanylate Cyclase; Locus Coeruleus; Male; Morphine; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2000 |
Failure of naloxone to reverse brimonidine-induced coma in an infant.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Coma; Dose-Response Relationship, Drug; Humans; Infant; Naloxone; Narcotic Antagonists; Quinoxalines; Treatment Failure | 2002 |
Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Female; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Naloxone; Quinoxalines; Receptors, Opioid, mu; Somatostatin | 2002 |
Caroverine inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Conditioning, Classical; Male; Morphine; Naloxone; Narcotic Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2003 |
Blockade of ionotropic glutamatergic transmission in the ventral tegmental area attenuates the physical signs of morphine withdrawal in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area; Weight Loss | 2004 |
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms | 2005 |
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2005 |
Ionotropic glutamatergic neurotransmission in the ventral tegmental area modulates DeltaFosB expression in the nucleus accumbens and abstinence syndrome in morphine withdrawal rats.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Nucleus Accumbens; Protein Isoforms; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2005 |
Double dissociation in the neural substrates of acute opiate dependence as measured by withdrawal-potentiated startle.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Fear; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2006 |
Intrathecally injected morphine inhibits inflammatory paw edema: the involvement of nitric oxide and cyclic-guanosine monophosphate.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Neutrophil Infiltration; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Peroxidase; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sildenafil Citrate; Spinal Cord; Sulfones; Time Factors | 2008 |
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dopamine; Drug Interactions; Enzyme Inhibitors; Indomethacin; Interleukin-1beta; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Sensory Receptor Cells; Signal Transduction | 2008 |
Brimonidine tartrate poisoning in children: frequency, trends, and use of naloxone as an antidote.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Child, Preschool; Humans; Infant; Naloxone; Poisoning; Quinoxalines; Retrospective Studies | 2009 |
Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthralgia; Arthritis, Experimental; Carbolines; Chemokine CXCL1; Chemokines; Cyclic GMP; Guanylate Cyclase; Injections, Intra-Articular; Interleukin-1; Joints; Male; Naloxone; Narcotic Antagonists; Neutrophils; Nociception; Osteoarthritis; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Tadalafil; Tumor Necrosis Factor-alpha; Zymosan | 2011 |
Mechanisms underlying the antinociceptive effect of mangiferin in the formalin test.
Topics: Analgesics; Animals; Capsaicin; Formaldehyde; Glyburide; Male; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Nociception; Quinoxalines; Rats; Rats, Wistar; Serotonin; Xanthones | 2013 |
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.
Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds | 2013 |
Systemic toxicity from subcutaneous brimonidine injection successfully treated with naloxone.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Bradycardia; Brimonidine Tartrate; Drug Overdose; Female; Glaucoma; Humans; Hypotension; Infant; Injections, Subcutaneous; Lethargy; Naloxone; Ophthalmic Solutions; Quinoxalines | 2022 |