quinoxalines has been researched along with n-methylaspartate in 427 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (4.92) | 18.7374 |
| 1990's | 270 (63.23) | 18.2507 |
| 2000's | 105 (24.59) | 29.6817 |
| 2010's | 30 (7.03) | 24.3611 |
| 2020's | 1 (0.23) | 2.80 |
| Authors | Studies |
|---|---|
| Fedorov, NB; Reymann, KG; Screbitsky, VG | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Manabe, T; Nicoll, RA; Renner, P | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Dudek, FE; Peacock, WJ; Wuarin, JP | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Kelly, JB; Wu, SH | 1 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Czepita, D; Daw, N; Fox, K; Sato, H | 1 |
| Nicklas, WJ; Zeevalk, GD | 2 |
| Weiland, NG | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Flavin, MP; Riopelle, RJ; Yang, Y | 1 |
| Pinnock, RD | 1 |
| Rekling, JC | 1 |
| Dingledine, R; McBain, C | 1 |
| Ault, B; Martin, D; Nadler, JV | 1 |
| Pittaluga, A; Raiteri, M | 2 |
| Cumberbatch, M; King, AE; Lopez-Garcia, JA | 1 |
| Kurusu, R; Sakurai, H; Sano, K; Tsuchiya, T; Tsuda, M | 1 |
| Lanius, RA; Shaw, C | 2 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Evans, PD; Merzon, RM; Reale, V; Villegas, J | 1 |
| Arai, A; Lynch, G; Muller, D | 1 |
| Bobichon, C; Cordi, A; Curutchet, P; de Carvalho, LP; Guet, T; Lambolez, B; Lepagnol, JM; Moreau, C; Randle, JC | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Lodge, D; Millar, JD; Pralong, E | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Lodge, D; Zeman, S | 1 |
| Morán, J; Rivera-Gaxiola, M | 1 |
| Calder, LD; Karler, R | 1 |
| DeFeo, PA; Hargrove, H; Patel, J; Salama, AI; Thompson, C; Zinkand, WC | 1 |
| Albrecht, RF; Hoffman, WE; Kochs, E; Pelligrino, D; Schulte am Esch, J; Werner, C | 1 |
| Denavit-Saubie, M; Foutz, AS; Pierrefiche, O; Schmid, K | 1 |
| Jones, MG; Lodge, D; Palmer, AJ | 1 |
| Supko, DE; Uretsky, NJ; Wallace, LJ | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Hablitz, JJ; Lee, WL | 1 |
| Crane, AM; Driscoll, BF; Law, MJ | 1 |
| Aizenman, E; Lipton, SA; Sucher, NJ | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Frenguelli, BG | 1 |
| Bovolin, P; Costa, E; Grayson, DR; Memo, M | 1 |
| Rosenberg, PA | 1 |
| Houk, JC; Keifer, J | 1 |
| Shreve, PE; Uretsky, NJ | 2 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Choi, DW; Koh, JY | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Turner, DA; Wheal, HV | 1 |
| Lai, YY; Siegel, JM | 1 |
| Collins, GG | 1 |
| Eaton, SA; Roberts, WA; Salt, TE | 1 |
| Schmidt, M | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Avoli, M; Hwa, GG | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Esguerra, M; Kwon, YH; Sur, M | 1 |
| Li, J; Smith, SS | 1 |
| Morita, Y; Nishimura, S; Sorimachi, M | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Coenen, AM; Peeters, BW; Ramakers, GM; Vossen, JM | 1 |
| Jean, A; Kessler, JP | 1 |
| Cerne, R; Gerber, G; Randić, M | 1 |
| Christenson, J; Grillner, S | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Billard, JM; Daniel, H; Pumain, R | 1 |
| Guy, N; Ropert, N | 1 |
| Hankins, MW; Ikeda, H | 1 |
| Jacocks, HM; McMahon, PN; Werling, LL | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Kawai, N; Robinson, HP; Sahara, Y | 1 |
| Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N | 1 |
| Arancio, O; MacDermott, AB; Murase, K; Yoshimura, M | 1 |
| Lewis, DV; Martin, D; Morrisett, RA; Oetting, TA; Swartzwelder, HS; Wilson, WA | 1 |
| Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C | 1 |
| Lewis, DV; Morrisett, RA; Mott, DD; Swartzwelder, HS; Wilson, WA | 1 |
| Calder, LD; Karler, R; Turkanis, SA | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Evans, RH; Long, SK; Siarey, RJ; Smith, DA | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Dun, NJ; Mo, N; Shen, E | 1 |
| Costa, E; Grayson, DR; Szekely, AM | 1 |
| Hestrin, S; Nicoll, RA; Perkel, DJ; Sah, P | 1 |
| Dudek, FE; van den Pol, AN; Wuarin, JP | 1 |
| Hablitz, JJ; Sutor, B | 1 |
| Aizenman, E; Loring, RH; Rosenberg, PA; White, WF | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Collingridge, GL; Davies, SN | 1 |
| Audinat, E; Gähwiler, BH; Knöpfel, T | 1 |
| Cler, JA; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Hoehn, K; White, TD | 1 |
| Kerwin, R; Meldrum, B; Patel, S | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Keith, RA; Klika, AB; Mangano, TJ; Patel, J; Salama, AI; Zinkand, WC | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Baker, RE; Ruijter, JM | 1 |
| Honoré, T; Imperato, A; Jensen, LH | 1 |
| Dingledine, R; Kleckner, NW | 1 |
| Buckley, KS; Collins, GG | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Drejer, J; Honoré, T; Jensen, LH; Sheardown, MJ; Stidsen, CE | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Jahr, CE; Lester, RA; Parker, JD; Quarum, ML; Weber, E | 1 |
| Harris, KM; Miller, RJ | 1 |
| Costa, E; Favaron, M; Guidotti, A; Manev, H | 1 |
| Choi, DW; Hartley, DM | 1 |
| Dubinsky, JM; Rothman, SM; Yamada, KA | 1 |
| Drejer, J; Honoré, T | 1 |
| Cohen, A; Erez, U; Frenk, H; Goldberg, O; Teichberg, VI | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Sheardown, MJ | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 2 |
| Ben-Ari, Y; Cherubini, E; Gho, M; Neuman, RS | 1 |
| Kauer, JA; Malenka, RC; Nicoll, RA | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Lerma, J; Mellström, B; Naranjo, JR; Paternain, AV | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Fedorov, NB; Reymann, KG | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Jahr, CE; Tong, G | 1 |
| Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL | 1 |
| Lees, GJ; Leong, W | 1 |
| Barnes, K; Buchan, AM; Huang, ZG; Lesiuk, HJ; Smith, KE; Xue, D | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R; Tribillac, F | 1 |
| Gyevai, A; Mike, A; Osipenko, O; Vizi, ES | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Massieu, L; Tapia, R | 1 |
| Chizh, BA; Cumberbatch, MJ; Headley, PM | 2 |
| Hamada, T; Ono, M; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| Adler-Graschinsky, E; Butta, NV; Lorenzo, PS | 1 |
| Gruner, R; Parsons, CG; Rozental, J | 1 |
| Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E | 1 |
| Greenamyre, JT; Greene, JG | 1 |
| Dowling, JE; Grant, GB | 1 |
| Balázs, R; Hack, N | 1 |
| Boulton, CL; Garthwaite, J; Mayer, B; Nielsen, EB; Schmidt, K; Southam, E | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Cervo, L; Samanin, R | 1 |
| Ehrenberger, K; Felix, D | 1 |
| Lodge, D; Palmer, AJ | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Block, F; Schwarz, M; Sontag, KH | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| French, ED; Wang, T | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Grosche, J; Kettenmann, H; Müller, T; Ohlemeyer, C | 1 |
| Fukuda, H; Hicks, TP; Kobayashi, T; Nagao, T; Oka, JI | 1 |
| Dykstra, CL; Gebhart, GF; Meller, ST | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Block, F; Schmitt, T; Schwarz, M | 1 |
| Choi, DW; Goldberg, MP; Gottlieb, DI; Huettner, JE; Turetsky, DM | 1 |
| Constantine-Paton, M; Hickmott, PW | 1 |
| Greer, RA; Hall, ME; Stewart, JM | 1 |
| Choi, DW; Gwag, BJ; Koh, JY; Lobner, D | 1 |
| Ossowska, K; Wolfarth, S | 1 |
| Gonzales, RA; Roper, LC | 1 |
| Krieger, AJ; Maeda, M; Morino, M; Nakai, M; Sapru, HN | 1 |
| Gaspary, HL; Graham, SH; Simon, RP | 1 |
| Chetkovich, DM; Sweatt, JD | 1 |
| Abercrombie, ED; Keefe, KA; Sved, AF; Zigmond, MJ | 1 |
| López-Colomé, AM; Ortega, A; Romo-de-Vivar, M | 1 |
| Brooks, KJ; Kauppinen, RA | 1 |
| Heinemann, U; Igelmund, P; Leschinger, A; Stabel, J | 1 |
| Chazot, PL; Cik, M; Stephenson, FA | 1 |
| Fan, P; Szerb, JC | 1 |
| Nistri, A; Stocca, G | 1 |
| Puro, DG; Uchihori, Y | 1 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Bernard, J; Massicotte, G; Ohayon, M | 1 |
| Scholfield, CN; Yassin, M | 1 |
| Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Huang, W; West, M | 1 |
| Gebhart, GF; Kolhekar, R | 1 |
| Giboney, P; Simmons, DD; Song, C | 1 |
| Hunter, JC; Singh, L | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Baudy, RB; Bramlett, DR; Conklin, M; Emrey, TA; Greenblatt, LP; Jirkovsky, IL; Kowal, DM; Russo, RJ; Simmonds, JT; Stein, RP | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Dai, X; Douglas, JR; Jordan, LM; Noga, BR | 1 |
| Kessler, JP | 1 |
| D'Angelo, E; Rossi, P; Taglietti, V | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Corner, MA; de Wit, C; Ramakers, GJ; Wolters, PS | 1 |
| Abercrombie, ED; Keefe, KA; Zigmond, MJ | 1 |
| Trombley, PQ; van den Pol, AN | 1 |
| Tang, CM; Yamada, KA | 1 |
| Buchwald, NA; Cohen, RW; Levine, MS; Radisavljevic, Z; Siviy, SM; Walsh, JP | 1 |
| Cerne, R; Jiang, MC; Randić, M | 1 |
| Block, F; Schwarz, M | 1 |
| Heary, RF; Krieger, AJ; Maniker, AH; Sapru, HN | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Chen, J; Graham, SH; Lan, JQ; Simon, RP | 1 |
| Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P | 1 |
| Davies, LR; Gerhold, TD; Kamath, SH; Narimatsu, E; Sokoll, MD; Tsai, YC | 1 |
| Bernert, H; Turski, L | 1 |
| Kumar, V; Lincoln, GA; Tortonese, DJ | 1 |
| McCaslin, PP; Oh, S | 1 |
| Bereiter, DA; Bereiter, DF | 1 |
| Akerman, KE; Holopainen, I; Janáky, R; Oja, SS; Varga, V | 1 |
| Hu, XT; White, FJ | 1 |
| Choi, EJ; Leem, JW; Paik, KS; Park, ES | 1 |
| Miller, RF; Yu, W | 1 |
| Beckstead, RM | 1 |
| Cole, BJ; Stephens, DN | 1 |
| Fleischer-Lambropoulos, E; Geladopoulos, T; Kazazoglou, T; Kentroti, S; Stefanis, C; Vernadakis, A | 1 |
| Ebert, B; Krogsgaard-Larsen, P; Madsen, U; Søby, KK | 1 |
| Ferger, D; Krieglstein, J | 1 |
| Erdõ, SL; Molnár, P | 1 |
| Fedele, E; Jin, Y; Raiteri, M; Varnier, G | 1 |
| Ben-Yoseph, O; Boxer, PA; Ross, BD | 1 |
| Cumberbatch, MJ; Headley, PM; Herrero, JF | 1 |
| Bonham, AC; Wilson, CG; Zhang, Z | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Shiraishi, K | 1 |
| Gisselmann, G; Gottmann, K; Hatt, H; Mehrle, A | 1 |
| Fergus, A; Lee, KS | 1 |
| Cebers, G; Hou, YN; Liljequist, S; Terenius, L | 1 |
| Bettelini, L; Corsi, M; Fina, P; Trist, DG | 1 |
| Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Yamada, K | 1 |
| Krassioukov, AV; Krenz, NR; Maiorov, DN; Weaver, LC | 1 |
| Katz, LC; Roerig, B | 1 |
| Bhat, GK; Brann, DW; Mahesh, VB; Ping, L | 1 |
| Cook, JC; Gregg, AE; Sanders, BJ; Soltis, RP | 1 |
| Danthi, SN; Hill, RA; Layer, RT; Miller, DD; Shams, G; Tai, H; Uretsky, NJ; Wallace, LJ; Weinstein, DM; Willins, D | 1 |
| Canzoniero, LM; Choi, DW; Kerchner, GA; Koh, JY; Sensi, SL; Ying, HS; Yu, SP | 1 |
| Ger, LP; Lin, HC; Lo, WC; Tseng, CJ; Tung, CS | 1 |
| Bickler, PE; Bornheim, LM; Gray, AT; Hampson, AJ; Hansen, BM; Leonoudakis, DJ; Scanziani, M; Yost, CS | 1 |
| Bianchi, L; Della Corte, L; Giovannini, MG; Pepeu, G; Rakovska, A | 1 |
| Jordan, D; Ramage, AG; Wang, Y | 1 |
| Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G | 1 |
| De Laurentiis, A; del Carmen Díaz, M; Duvilanski, B; Lasaga, M; Pampillo, M; Pisera, D; Seilicovich, A; Theas, S | 1 |
| Endo, T; Hara, S; Iwata, N; Kano, S; Kuriiwa, F; Mukai, T; Yanase, T | 1 |
| Farre, C; Jacobson, I; Jardemark, K; Orwar, O; Zare, RN | 1 |
| Bonnot, A; Morin, D; Viala, D | 1 |
| Näsström, J; Sequeira, S | 1 |
| Lingenhöhl, K; Pozza, MF | 1 |
| Aguilar, E; Pinilla, L; Tena-Sempere, M | 2 |
| Mifflin, SW; Zhang, J | 1 |
| Fartacek, R; Geretsegger, C | 1 |
| Balázs, R; Facchinetti, F; Hack, NJ | 1 |
| Gatherer, M; Sundstrom, LE | 1 |
| Holmberg, L; Souverbie, F; Sundström, E | 1 |
| Bowen, CA; Gatto, GJ; Grant, KA | 1 |
| Roberts, A; Zhao, FY | 1 |
| Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Yasuda, S | 1 |
| Faddis, BT; Goldberg, MP; Hasbani, MJ; Hyrc, KL; Romano, C | 1 |
| Chen, YH; Fu, WM; Liou, HC; Wang, SM | 1 |
| Acklin, P; Auberson, YP; Bischoff, S; Moretti, R; Ofner, S; Schmutz, M; Veenstra, SJ | 1 |
| Badre, SE; Morsette, DJ; Sladek, CD; Swenson, KL | 1 |
| Gao, F; Wu, SM | 1 |
| Goraca, A | 2 |
| Blanco, R; de la Villa, P | 1 |
| Abrahams, TP; Hornby, PJ; Krowicki, ZK; Sivarao, DV | 1 |
| Linden, R; Martins, RA; Rocha, M | 1 |
| Blaszczak, P; Kleinrok, Z; Saran, T; Turski, WA; Urbanska, EM | 1 |
| Arvigo, D; Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Albers, HE; Gillespie, CF; Marvel, CL; Mintz, EM; Price, KM | 1 |
| Dong, LP; Wang, TY | 1 |
| Dogas, Z; Hopp, FA; Krolo, M; McCrimmon, DR; Stuth, EA; Tonkovic-Capin, M; Zuperku, EJ | 1 |
| Song, XJ; Zhao, ZQ | 1 |
| Dean, C; Hopp, FA; Seagard, JL | 1 |
| De Laurentiis, A; Díaz, MC; Duvilanski, B; Lasaga, M; Pampillo, M; Pisera, D; Seilicovich, A | 1 |
| Carleton, A; Castillo, PE; Lledo, PM; Vincent, JD | 1 |
| Chen, J; Li, H; Li, Z; Luo, C; Zheng, J | 1 |
| Hanania, T; Johnson, KM | 1 |
| Connor, JA; Yuzaki, M | 1 |
| Brambilla, D; Mancia, M; Manfridi, A | 1 |
| Denizot, JP; Métin, C; Ropert, N | 1 |
| Lanza, M; Makovec, F | 1 |
| Berkman, K; Gören, MZ; Onat, F | 1 |
| Calton, JL; Kang, MH; Moore, SD; Wilson, WA | 1 |
| Hirano, A; Nakanishi, J; Radecka, H; Sugawara, M; Umezawa, Y | 1 |
| Bräuner-Osborne, H; Eriksen, L; Krogsgaard-Larsen, P; Lützhøft, HH; Madsen, U; Poulsen, MV; Sløk, FA; Stensbøl, TB | 1 |
| Gonzalez, M; Infante, C; Motles, E | 1 |
| Pollard, M | 1 |
| Gähwiler, BH; Gerber, U; Jabaudon, D; Scanziani, M | 1 |
| Durand, J; Ruiz, A | 1 |
| Cobanoğlu, S; Görgülü, A; Kiriş, T; Küçük, M; Turkoğlu, U; Unal, F | 1 |
| Faulkner-Jones, BE; Sanes, JR; Wong, RO; Wong, WT | 1 |
| Friedman, D; Halabisky, B; Radojicic, M; Strowbridge, BW | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Morinobu, S; Yasuda, S | 1 |
| Barat, A; Burgos, JS; Ramírez, G | 1 |
| Mao, L; Wang, JQ | 1 |
| Marcoli, M; Maura, G; Pepicelli, O; Raiteri, M; Rosu, C; Viola, C | 1 |
| Iida, S; Ishihama, K; Kogo, M; Koizumi, H; Matsuya, T; Mori, A; Tanaka, S | 1 |
| Ikonomidou, C; Stefovska, V; Turski, L | 1 |
| Axer, H; Steinbusch, HW; Teunissen, CE | 1 |
| Aguilar, E; Gonzalez, LC; Pinilla, L; Tena-Sempere, M | 1 |
| Shi, WX; Zhang, XX | 1 |
| Bardoul, M; Drian, MJ; König, N | 1 |
| Geurtsen, AM; Hamstra, R; Pennartz, CM | 1 |
| Blaabjerg, M; Bonde, C; Kristensen, BW; Zimmer, J | 1 |
| Bull, DJ; Carr, CL; Fray, MJ; Gautier, EC; Mowbray, CE; Stobie, A | 1 |
| Canonico, PL; Dianzani, C; Fantozzi, R; Lombardi, G; Miglio, G | 1 |
| Carlà, V; Catarzi, D; Colotta, V; Costagli, C; Filacchioni, G; Galli, A; Varano, F | 1 |
| Schoppa, NE; Westbrook, GL | 1 |
| Chai, CY; Su, CK; Wang, Y; Wu, WC | 1 |
| Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
| Gray, R; Johnston, D; Liang, Y; Yuan, LL | 1 |
| Attwell, D; Hamann, M; Marie, H; Rossi, DJ | 1 |
| Ehrenberger, K; Felix, D; Oestreicher, E | 1 |
| Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P | 1 |
| Behl, B; Henn, C; Hofmann, HP; Lubisch, W; Reeb, J; Regner, F; Vierling, M | 1 |
| Feroah, TR; Forster, HV; Fuentes, CG; Hodges, M; Martino, P; Pan, L; Rice, T; Wenninger, J | 2 |
| Baldridge, WH; Baptiste, DC; Chauhan, BC; Hartwick, AT; Jollimore, CA; Kelly, ME; Tremblay, F | 1 |
| Fujimori, S; Hinoi, E; Takarada, T; Taniura, H; Yoneda, Y | 1 |
| Bruno, JP; Kravitz, BA; Neigh-McCandless, G; Sarter, M | 1 |
| Rubaj, A; Sieklucka-Dziuba, M; Zgodziński, W | 1 |
| Mele, A; Oliverio, A; Roullet, P; Sargolini, F | 1 |
| Ehrenberger, K; Hummel, T; Quint, C; Temmel, AF | 1 |
| Lin, TB | 2 |
| Cole, S; Gedge, J; Roffey, S; Walker, D; Webster, R; Wild, W | 1 |
| Albers, HE; Fukuhara, C; Paul, KN; Tosini, G | 1 |
| Arendt-Nielsen, L; Sumikura, H | 1 |
| Choi, JH; Chun, SW; Kim, MS; Park, BR | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Pittaluga, A; Pugliese, AM; Romanelli, MN | 1 |
| Duan, SM; Xu, AJ; Zeng, YM | 1 |
| Cory-Slechta, DA; Reeves, R; Thiruchelvam, M | 1 |
| Chianca, DA; Dragon, DN; Lin, LH; Talman, WT | 1 |
| Häusser, M; Nelson, SB; Sjöström, PJ; Turrigiano, GG; Watt, AJ | 1 |
| Balster, RL; Wiley, JL | 1 |
| Arrigoni, E; Greene, RW | 1 |
| Grebenyuk, S; Kirichok, Y; Krishtal, O; Lozovaya, N; Melnik, S; Tsintsadze, T | 1 |
| Leung, LS; Shen, B | 1 |
| Cechova, S; Pajewski, TN | 1 |
| Auberson, YP; Bashir, ZI; Brown, MW; Collingridge, GL; Johnson, BE; Massey, PV; Molnar, E; Moult, PR | 1 |
| Ritchie, MD; Vanhoose, AM; Winder, DG | 1 |
| Chen, Z; Duan, M; Ruan, R; Tan, L; Ulfendahl, M | 1 |
| Kolb, JE; Levine, ES; Trettel, J | 1 |
| Dagonnier, M; Laute, MA; Manto, M; Pandolfo, M | 1 |
| Brennan, TJ; Pogatzki-Zahn, EM; Zahn, PK | 1 |
| Hashikawa, T; Hayashi, Y; Kobayashi, S; Miyawaki, A; Nagai, T; Nakagawa, T; Neve, RL; Okamoto, K; Takao, K | 1 |
| Caroni, P; de Paola, V; Gähwiler, BH; Hugel, S; Mateos, JM; McKinney, RA; Richards, DA | 1 |
| Knöpfel, T; Mutoh, H; Yuan, Q | 1 |
| Fowler, L; Pearce, B; Watts, J; Whitton, PS | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YR | 1 |
| Boriboun, C; Marks, JD; Wang, J | 1 |
| Bottjer, SW | 1 |
| An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
| Laute, MA; Manto, M; Pandolfo, M | 1 |
| Iino, M; Kakizawa, S; Kano, M; Miyazaki, T; Watanabe, M; Yanagihara, D | 1 |
| Kanno, T; Maruo, K; Maruo, S; Nishizaki, T; Yaguchi, T; Yamamoto, S; Yashiya, S | 1 |
| Bonci, A; Borgland, SL; Fields, HL; Sarti, F; Taha, SA | 1 |
| Baudry, M; Zhou, M | 1 |
| Chen, GD; Chen, JC; Chen, MJ; Ho, YC; Huang, PC; Liao, JM; Lin, JJ; Lin, SY; Lin, TB; Pan, SF; Peng, HY | 1 |
| Amatore, C; Arbault, S; Cauli, B; Geoffroy, H; Guille, M; Hamel, E; Rancillac, A; Rossier, J; Tong, XK | 1 |
| Yonehara, N; Yoshimura, M | 1 |
| Bannister, NJ; Bartlett, TE; Bashir, ZI; Bortolotto, ZA; Collett, VJ; Collingridge, GL; Dargan, SL; Fitzjohn, SM; Lodge, D; Massey, PV | 1 |
| Abidin, I; Eysel, UT; Köhler, T; Lessmann, V; Mittmann, T; Weiler, E; Zoidl, G | 1 |
| Dai, Q; Gao, R; Meng, H; Qiao, X | 1 |
| Bayer, L; Eggermann, E; Jones, BE; Mühlethaler, M; Saint-Mleux, B; Serafin, M | 1 |
| Coserea, I; Fuchs, EC; Köhr, G; Monyer, H; Pawlak, V; Seeburg, PH; von Engelhardt, J | 1 |
| Anrather, J; Iadecola, C; Kawano, T; Kunz, A; Orio, M; Zhou, P | 1 |
| Chandler, LJ; Luong, NT; Mulholland, PJ; Woodward, JJ | 1 |
| Crair, MC; Shah, RD | 1 |
| Liang, SL; McCarthy, MM; Schwarz, JM; Thompson, SM | 1 |
| Agey, P; Dong, CJ; Guo, Y; Hare, WA; Wheeler, L | 2 |
| Asrar, S; Huang, WW; Jia, Z; Meng, Y; Todorovski, Z; Zhou, Z | 1 |
| Del Arco, A; Mora, F; Segovia, G | 1 |
| Delgado, A; Oviedo, A; Querejeta, E | 1 |
| Dybała, M; Nowak, G; Pilc, A; Poleszak, E; Siwek, A | 1 |
| Itoh, K; Watanabe, M | 1 |
| de Menezes, RC; DiMicco, JA; Fontes, MA; Zaretsky, DV | 1 |
| Cohen, D; Segal, M | 1 |
| Cheevers, CV; Donello, JE; Gil, DW; Kedzie, KM; Manlapaz, CA; Rao, S; Tang, E | 1 |
| Mahmoudian, M; Rahbar-Roshandel, N; Rahimi-Moghaddam, P; Tavakoli-Far, B | 1 |
| Blankenship, AG; Copenhagen, DR; Edwards, RH; Feller, MB; Ford, KJ; Johnson, J; Seal, RP | 1 |
| Adeola, M; Loo, M; Patil, T; Poles, A; Raffa, RB; Rawls, SM; Raymondi, N; Thomas, T | 1 |
| Christie, JM; Jahr, CE | 1 |
| Fu, R; Heckman, CJ; Jiang, M; Schuster, JE; Siddique, T | 1 |
| Bose, R; Parkinson, FE; Zamzow, CR | 1 |
| Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y | 1 |
| Chen, Y; Feng, C; Xiao, L | 1 |
| Barbosa, RM; Cadenas, E; Gerhardt, G; Laranjinha, J; Lourenço, CF; Santos, R | 1 |
| Gire, DH; Pandipati, S; Schoppa, NE | 1 |
| Li, WC; Roberts, A; Soffe, SR | 1 |
| Ashby, MC; Isaac, JT; Matta, JA; Roche, KW; Sanz-Clemente, A | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Dehmel, M; Fischer, C; Henle, F; Leemhuis, J; Meyer, DK | 1 |
| Carter, AG; Chalifoux, JR | 1 |
| Auberson, YP; Bajouco, LM; Ferreira, IL; Mota, SI; Oliveira, CR; Rego, AC | 1 |
| Coccurello, R; Mele, A; Oliverio, A | 1 |
| Harley, CW; Yuan, Q | 1 |
| Costa-Campos, L; Elisabetsky, E; Garcia, CR; Linck, VM; Pilz, LK | 1 |
| Antunes-Rodrigues, J; Busnardo, C; Corrêa, FM; Crestani, CC; Resstel, LB; Tavares, RF | 1 |
| Xie, G; Ye, JH | 1 |
| Brittain, JM; Brittain, MK; Brustovetsky, N; Brustovetsky, T; Cummins, TR; Khanna, R | 1 |
| Mejia-Gervacio, S | 1 |
| Crawford, DC; Jiang, X; Mennerick, S; Taylor, A | 1 |
| Nicoll, RA; Shipman, SL | 1 |
| Chick, WS; Dell'Acqua, ML; Freund, RK; Gibson, ES; Gorski, JA; Lam, P; Sanderson, JL | 1 |
| Ben Hamida, S; Carnicella, S; Darcq, E; Gibb, SL; Lanfranco, MF; Ron, D; Wang, J; Zhu, W | 1 |
| Morales, M; Spear, LP; Varlinskaya, EI | 1 |
| Nowak, G; Pilc, A; Poleszak, E; Popik, P; Siwek, A; Szewczyk, B; Wolak, M | 1 |
| Carr, JA; Fu, Z; Go, A; Pamenter, ME; Powell, FL; Reid, SG | 1 |
| Gmiro, VE; Serdyuk, SE; Veselkina, OS | 1 |
| Fukushima, K; Imaizumi, Y; Ito, M; Kohmura, N; Sawada, K; Sugawara, M; Tabata, Y; Yamazaki, K | 1 |
| Asensio, CS; Edwards, RH; Incontro, S; Nicoll, RA | 1 |
| Chitravanshi, VC; Kawabe, K; Sapru, HN | 1 |
| Carter, AG; McGarry, LM | 1 |
| Bing, YH; Chu, CP; Cui, BR; Cui, LN; Li, BX; Qiu, DL; Zhang, GJ; Zhang, XY | 1 |
1 review(s) available for quinoxalines and n-methylaspartate
| Article | Year |
|---|---|
Quinoxalinediones as excitatory amino acid antagonists in the vertebrate central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Binding, Competitive; Central Nervous System; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Spinal Cord; Structure-Activity Relationship; Vertebrates | 1990 |
1 trial(s) available for quinoxalines and n-methylaspartate
| Article | Year |
|---|---|
The quinoxaline derivative caroverine in the treatment of sensorineural smell disorders: a proof-of-concept study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; N-Methylaspartate; Olfaction Disorders; Quinoxalines; Sensory Thresholds; Smell; Zinc Sulfate | 2002 |
425 other study(ies) available for quinoxalines and n-methylaspartate
| Article | Year |
|---|---|
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Phenols; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1992 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Synapses; Tetrodotoxin | 1992 |
The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Enkephalins; Functional Laterality; Gene Expression; Hippocampus; Kainic Acid; Kinetics; Male; Microinjections; N-Methylaspartate; Nucleic Acid Hybridization; Protein Precursors; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Single-electrode voltage-clamp analysis of the N-methyl-D-aspartate component of synaptic responses in neocortical slices from children with intractable epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Aging; Bicuculline; Cerebral Cortex; Child; Child, Preschool; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Female; Humans; Infant; Male; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1992 |
Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Bicuculline; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1992 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
NMDA, non-NMDA and glycine receptors mediate binaural interaction in the lateral superior olive: physiological evidence from mouse brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Functional Laterality; Glycine; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Olivary Nucleus; Quinoxalines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
The effect of visual experience on development of NMDA receptor synaptic transmission in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Cats; Darkness; Evoked Potentials; Iontophoresis; Light; N-Methylaspartate; Photic Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Vision, Ocular; Visual Cortex; Visual Perception | 1992 |
NMDA receptors, cellular edema, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Dizocilpine Maleate; Edema; Electron Transport; Glycolysis; Hypoglycemia; Hypoxia; Iodoacetates; Iodoacetic Acid; Ischemia; N-Methylaspartate; Potassium Cyanide; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Tetrodotoxin | 1992 |
Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Binding, Competitive; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Ovariectomy; Progesterone; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
The effect of hypoxia on neurotransmitter phenotype of forebrain cholinergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cell Hypoxia; Cells, Cultured; Choline O-Acetyltransferase; Embryo, Mammalian; Glutamates; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Growth Factors; Neurons; Phenotype; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Interaction between thyrotropin-releasing hormone (TRH) and NMDA-receptor-mediated responses in hypoglossal motoneurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Brain Stem; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1992 |
Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials, Somatosensory; Hippocampus; Hypertonic Solutions; In Vitro Techniques; Kainic Acid; Kinetics; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1992 |
NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Female; Hippocampus; In Vitro Techniques; Manganese; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Zinc | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. III. Changes in the NMDA receptor complex induced by their functional cooperation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1992 |
Antagonism of synaptic potentials in ventral horn neurones by 6-cyano-7-nitroquinoxaline-2,3-dione: a study in the rat spinal cord in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Electric Stimulation; Female; Half-Life; In Vitro Techniques; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Spinal Nerve Roots; Synapses | 1992 |
Stimulation of cultured cerebellar granule cells via glutamate receptors induces TRE- and CRE-binding activities mediated by common DNA-binding complexes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Cyclic AMP; DNA-Binding Proteins; Kainic Acid; Magnesium; Mice; Mice, Inbred ICR; Molecular Sequence Data; N-Methylaspartate; Protein Binding; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1992 |
Characterization and regulation of a high affinity [3H]CNQX labelled AMPA receptor in rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; Muscimol; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Neurotransmitter; Tritium | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
N-methyl-D-aspartate (NMDA) and non-NMDA (metabotropic) type glutamate receptors modulate the membrane potential of the Schwann cell of the squid giant nerve fibre.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Axons; Decapodiformes; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schwann Cells | 1992 |
Factors governing the potentiation of NMDA receptor-mediated responses in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Electrophysiology; Evoked Potentials; Female; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Structure-Activity Relationship; Synapses; Xenopus | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Pharmacological characterization of non-NMDA subtypes of glutamate receptor in the neonatal rat hemisected spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Methohexital; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Effect of potassium and N-methyl-D-aspartate on the aspartate aminotransferase activity in cultured cerebellar granule cells.
Topics: Analysis of Variance; Animals; Aspartate Aminotransferases; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Kinetics; Magnesium; N-Methylaspartate; Neurons; Nifedipine; Potassium; Quinoxalines; Rats; Tetrodotoxin | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Quisqualate neurotoxicity in rat cortical cultures: pharmacology and mechanisms.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Ketamine decreases plasma catecholamines and improves outcome from incomplete cerebral ischemia in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Epinephrine; Fentanyl; Ketamine; Male; N-Methylaspartate; Norepinephrine; Oxygen Consumption; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medulla.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Decerebrate State; Iontophoresis; Medulla Oblongata; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiratory Center | 1991 |
Excitatory amino acids: new tools for old stories or pharmacological subtypes of glutamate receptors: electrophysiological studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Stem; Cerebral Cortex; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Wasp Venoms | 1991 |
Activation of AMPA/kainic acid glutamate receptors in the zona incerta stimulates locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diencephalon; Ibotenic Acid; Injections; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, Neurotransmitter; Substantia Nigra | 1991 |
GABAA and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electricity; Epilepsy; Female; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Buffers; Cells, Cultured; Culture Media; Dizocilpine Maleate; Glutamates; Glutamic Acid; Mesencephalon; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cells, Cultured; Electrophysiology; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Retinal Ganglion Cells | 1991 |
Electrogenic uptake contributes a major component of the depolarizing action of L-glutamate in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport, Active; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synaptic Transmission | 1991 |
Regulation of gamma-aminobutyric acidA receptor subunit expression by activation of N-methyl-D-aspartate-selective glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamates; Glutamic Acid; Molecular Sequence Data; Muscimol; N-Methylaspartate; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger | 1991 |
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Role of excitatory amino acids in mediating burst discharge of red nucleus neurons in the in vitro turtle brain stem-cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Calcium; Cerebellum; Electric Stimulation; In Vitro Techniques; Iontophoresis; Magnesium; Microelectrodes; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Quisqualic Acid; Red Nucleus; Spinal Cord; Turtles | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Line; Cell Survival; Cerebral Cortex; Fetus; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Denervation; Evoked Potentials; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses | 1991 |
Pontomedullary glutamate receptors mediating locomotion and muscle tone suppression.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Female; Kainic Acid; Kinetics; Locus Coeruleus; Male; Medulla Oblongata; Motor Activity; Muscles; N-Methylaspartate; Pons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Pharmacological evidence that NMDA receptors contribute to mono- and di-synaptic potentials in slices of mouse olfactory cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Mice; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synapses | 1991 |
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Mediation of visual responses in the nucleus of the optic tract in cats and rats by excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Evoked Potentials; Evoked Potentials, Visual; Female; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Optic Chiasm; Photic Stimulation; Quinoxalines; Quisqualic Acid; Rats; Receptors, Neurotransmitter | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
NMDA and non-NMDA receptors mediate visual responses of neurons in the cat's lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Visual Perception | 1991 |
GABAB receptor stimulation by baclofen and taurine enhances excitatory amino acid induced phosphatidylinositol turnover in neonatal rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Calcium; Cerebellum; gamma-Aminobutyric Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Receptors, GABA-A; Taurine | 1991 |
N-methyl-D-aspartate and aspartate raise the cytosolic free calcium concentration by acting upon receptors transiently expressed on immature cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Gallopamil; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Purkinje Cells; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
CNQX, a new non-NMDA receptor antagonist, reduces spike wave discharges in the WAG/Rij rat model of absence epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Azasteroids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Female; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Postural Balance; Pregnanediones; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Evidence that activation of N-methyl-D-aspartate (NMDA) and non-NMDA receptors within the nucleus tractus solitarii triggers swallowing.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Facial Nerve; Glutamates; Glutamic Acid; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in rat spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Sensitivity of rubrospinal neurons to excitatory amino acids in the rat red nucleus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Cats; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Iontophoresis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Red Nucleus; Species Specificity | 1991 |
Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Serotonin; Synapses; Synaptic Transmission; Time Factors | 1991 |
Non-NMDA type excitatory amino acid receptors mediate rod input to horizontal cells in the isolated rat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Dark Adaptation; Membrane Potentials; N-Methylaspartate; Neurons; Photoreceptor Cells; Piperazines; Quinoxalines; Rats; Receptors, Amino Acid | 1991 |
Regulation of [3H]dopamine release from guinea pig striatum by NMDA receptor/channel activators and inhibitors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Glycine; Guinea Pigs; Ion Channels; Magnesium; Male; N-Methylaspartate; Piperazines; Pyrrolidines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1990 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Evoked Potentials; Hippocampus; Ion Channels; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Synapses | 1991 |
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P | 1991 |
Glutamate receptor agonist-induced inward currents in spinal dorsal horn neurons dissociated from the adult rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Ion Channels; Kainic Acid; N-Methylaspartate; Nerve Fibers; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord | 1991 |
Ethanol and magnesium ions inhibit N-methyl-D-aspartate-mediated synaptic potentials in an interactive manner.
Topics: Animals; Drug Interactions; Ethanol; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Synaptic Membranes | 1991 |
Endogenous adenosine release from hippocampal slices: excitatory amino acid agonists stimulate release, antagonists reduce the electrically-evoked release.
Topics: Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Hippocampus; Inosine; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
GABAB-receptor-mediated inhibition of the N-methyl-D-aspartate component of synaptic transmission in the rat hippocampus.
Topics: Animals; Baclofen; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Picrotoxin; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
DNQX blockade of amphetamine behavioral sensitization.
Topics: Amphetamine; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Haloperidol; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Seizures; Stereotyped Behavior | 1991 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synapses; Tetrodotoxin | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Action of the anti-ischemic agent ifenprodil on N-methyl-D-aspartate and kainate-mediated excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Animals; Chick Embryo; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperidines; Quinoxalines; Retina | 1990 |
APV-sensitive dorsal root afferent transmission to neonate rat sympathetic preganglionic neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Animals, Newborn; Electrophysiology; Ganglia, Sympathetic; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats; Spinal Cord; Synaptic Transmission | 1990 |
Transcriptional program coordination by N-methyl-D-aspartate-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Gene Expression; Immunoblotting; N-Methylaspartate; Neurons; Phencyclidine; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Transcription Factors; Transcription, Genetic | 1990 |
Excitatory synaptic currents in Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Synapses | 1990 |
Glutamate, the dominant excitatory transmitter in neuroendocrine regulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Calcium; Electric Stimulation; Glutamates; Glutamic Acid; Hypothalamus; Immunohistochemistry; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Neurons; Neurotransmitter Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Second Messenger Systems; Synapses | 1990 |
Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; Horseradish Peroxidase; Iontophoresis; Isoquinolines; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dihydroxyphenylalanine; Evoked Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Responses to excitatory amino acids of Purkinje cells' and neurones of the deep nuclei in cerebellar slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Animals, Newborn; Cells, Cultured; Cerebellar Nuclei; Cerebellum; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Rats | 1990 |
6,7-Dinitroquinoxaline-2,3-dione and 6-nitro,7-cyanoquinoxaline-2,3-dione antagonize responses mediated by N-methyl-D-aspartate and NMDA-associated glycine recognition sites in vivo: measurements of cerebellar cyclic-GMP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; Cyclic AMP; Glycine; Harmaline; Kinetics; Male; Mice; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Serine | 1990 |
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Animals; Calcium; Cerebral Cortex; Dipeptides; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Autoradiography; Female; Glutamates; Hippocampus; Humans; Kainic Acid; Male; Middle Aged; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; Schizophrenia; Tritium | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
6,7-Dinitroquinoxaline-2,3-dione blocks the cytotoxicity of N-methyl-D-aspartate and kainate, but not quisqualate, in cortical cultures.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Hippocampus; Kainic Acid; Ligands; N-Methylaspartate; Neurotoxins; Norepinephrine; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
The effects of potassium-induced depolarization, glutamate receptor antagonists and N-methyl-D-aspartate on neuronal survival in cultured neocortex explants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cell Survival; Cerebral Cortex; Culture Techniques; Electrophysiology; Glutamates; N-Methylaspartate; Neurons; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1990 |
Dopamine release in the nucleus caudatus and in the nucleus accumbens is under glutamatergic control through non-NMDA receptors: a study in freely-moving rats.
Topics: Animals; Behavior, Animal; Caudate Nucleus; Dialysis; Dopamine; Glutamates; Haloperidol; Kainic Acid; Male; N-Methylaspartate; Nucleus Accumbens; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors.
Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Biological Assay; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Xenopus laevis | 1989 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
Abolition of the NMDA-mediated responses by a specific glycine antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX).
Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Brain; Glycine; Kinetics; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Membranes | 1989 |
A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cortical Spreading Depression; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pregnancy; Pyrrolidinones; Quinoxalines; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Interaction of 6-cyano-7-nitroquinoxaline-2,3-dione with the N-methyl-D-aspartate receptor-associated glycine binding site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Glycine; N-Methylaspartate; Quinoxalines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Biological Transport; Calcium; Cell Survival; Cells, Cultured; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Protein Kinase C; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Quantitative physiological characterization of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kainic Acid; Mathematics; N-Methylaspartate; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Synapses | 1989 |
AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Oxazoles; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Substantia Innominata | 1989 |
New quinoxalinediones show potent antagonism of quisqualate responses in cultured mouse cortical neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Drug; Sodium | 1988 |
Anticonvulsant properties of 3-hydroxy-2-quinoxalinecarboxylic acid, a newly found antagonist of excitatory amino acids.
Topics: Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Structure-Activity Relationship | 1985 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
A new and specific non-NMDA receptor antagonist, FG 9065, blocks L-AP4-evoked depolarization in rat cerebral cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1988 |
6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1988 |
A persistent postsynaptic modification mediates long-term potentiation in the hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Glutamates; Hippocampus; Membrane Potentials; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1988 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Functional kainate-selective glutamate receptors in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Embryo, Mammalian; Hippocampus; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Simultaneous local pressure microejection of excitatory amino acids and field potential recording with a single micropipette in the hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Hippocampus; In Vitro Techniques; Injections, Jet; Iontophoresis; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar | 1993 |
Differential effects of NBQX on the distal and local toxicity of glutamate agonists administered intra-hippocampally.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Diazepam; Hippocampus; Injections; Kainic Acid; Limbic System; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate | 1993 |
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Male; N-Methylaspartate; Pilot Projects; Quinoxalines; Rats; Rats, Inbred SHR; Sodium Chloride | 1994 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Ischemia; Cochlea; Cochlear Microphonic Potentials; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Male; N-Methylaspartate; Neurons, Afferent; Neurotransmitter Agents; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 1994 |
AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Iontophoresis; Male; N-Methylaspartate; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Synaptic Transmission | 1994 |
N-methyl-D-aspartate induces phase shifts in circadian rhythm of neuronal activity of rat SCN in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dizocilpine Maleate; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Neurons; Neuropeptide Y; Quinoxalines; Rats; Rats, Wistar; Suprachiasmatic Nucleus | 1994 |
Effects of L-glutamate on the responses to nerve stimulation in rat isolated atria.
Topics: Adrenergic Fibers; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Atrial Function; Electric Stimulation; Female; Glutamates; Glutamic Acid; Heart Atria; Heart Rate; In Vitro Techniques; Kainic Acid; Male; Muscarinic Antagonists; N-Methylaspartate; Norepinephrine; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar | 1994 |
A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Hot Temperature; Injections, Intravenous; Iontophoresis; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord | 1994 |
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Superior Colliculi | 1994 |
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission | 1994 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins | 1995 |
Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Cattle; Cells, Cultured; Cerebellum; Cyclic GMP; Guanylate Cyclase; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar | 1995 |
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulpiride | 1995 |
Receptor pharmacological models for inner ear therapies with emphasis on glutamate receptors: a survey.
Topics: Animals; Cochlea; Ear Diseases; Ear, Inner; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory; Humans; Magnesium; N-Methylaspartate; Neurons, Afferent; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate | 1995 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Non-NMDA-mediated transmission of somatosensory-evoked potentials in the rat thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Anticonvulsants; Electric Stimulation; Evoked Potentials, Somatosensory; Glycine; Ibotenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stereotaxic Techniques; Synaptic Transmission; Thalamic Nuclei | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
NMDA-activated currents in Bergmann glial cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cell Membrane; Cerebellum; In Vitro Techniques; Ion Channels; Ketamine; Mice; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1993 |
NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Spinal Cord | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Carcinoma, Embryonal; Cell Differentiation; Dizocilpine Maleate; Electrophysiology; Female; Immunohistochemistry; Indicators and Reagents; Ion Channels; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Pregnancy; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tretinoin; Tumor Cells, Cultured | 1993 |
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rana pipiens; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Tetrodotoxin; Thalamus | 1993 |
Effects of L-glutamate, substance P and substance P(1-7) on cardiovascular regulation in the nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reference Values; Stereotaxic Techniques; Substance P | 1993 |
Potentiated necrosis of cultured cortical neurons by neurotrophins.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Mice; N-Methylaspartate; Necrosis; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotrophin 3; Quinoxalines; Receptors, AMPA | 1995 |
Stimulation of glutamate receptors in the intermediate/caudal striatum induces contralateral turning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Caudate Nucleus; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Injections; Male; N-Methylaspartate; Neostriatum; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
Ethanol effects of NMDA-stimulated levels of extracellular neurotransmitters by in vivo microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Effects of microinjection of N-methyl-D-aspartic acid into the nucleus tractus solitarii on cerebral blood flow in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Cerebrovascular Circulation; Male; Microinjections; Microspheres; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Vascular Resistance | 1994 |
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis.
Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury | 1994 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Stress-induced dopamine release in the neostriatum: evaluation of the role of action potentials in nigrostriatal dopamine neurons or local initiation by endogenous excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Dopamine; Electroshock; Homovanillic Acid; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Psychological; Substantia Nigra; Tetrodotoxin | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Pharmacological and electrographic properties of epileptiform activity induced by elevated K+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Carbachol; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quaternary Ammonium Compounds; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Temperature | 1993 |
Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Cell Death; Cell Line; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Transfection | 1993 |
Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CA1 pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Ammonium Chloride; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1993 |
Modulation by TRH of NMDA-elicited responses of CA1 neurones of the rat hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1994 |
Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Middle Aged; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction | 1993 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
Modulation of the AMPA receptor by phospholipase A2: effect of the antidepressant trimipramine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Drug Synergism; Hippocampus; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Synaptic Membranes; Synaptic Transmission; Trimipramine | 1994 |
NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Dizocilpine Maleate; Evoked Potentials; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Glutamate agonists and [3H]GABA release from rat hippocampal slices: involvement of metabotropic glutamate receptors in the quisqualate-evoked release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Spinal cord excitatory amino acids and cardiovascular autonomic responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular System; Heart Rate; N-Methylaspartate; Quinoxalines; Rabbits; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Vasoconstriction | 1994 |
NMDA and quisqualate modulation of visceral nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Colon; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Rectum | 1994 |
Kainic acid stimulates uptake of divalent cations in postnatal cochlear neurons.
Topics: Animals; Cations, Divalent; Cobalt; Cochlea; Cricetinae; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Organ Culture Techniques; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate | 1994 |
Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat.
Topics: Analgesics; Animals; Formaldehyde; Inflammation; Male; N-Methylaspartate; Nociceptors; Pain Measurement; Pipecolic Acids; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
NMDA and non-NMDA receptors may play distinct roles in timing mechanisms and transmission in the feline respiratory network.
Topics: Action Potentials; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Carbon Dioxide; Cats; Dizocilpine Maleate; N-Methylaspartate; Neurons; Phrenic Nerve; Pulmonary Alveoli; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Synaptic Transmission; Time Factors | 1994 |
Potent quinoxaline-spaced phosphono alpha-amino acids of the AP-6 type as competitive NMDA antagonists: synthesis and biological evaluation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; In Vitro Techniques; Male; Mice; Models, Molecular; Molecular Conformation; N-Methylaspartate; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
The effects of intrathecal administration of excitatory amino acid agonists and antagonists on the initiation of locomotion in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Decerebrate State; Electromyography; Glutamates; Glutamic Acid; Hindlimb; Injections, Spinal; Kainic Acid; Laminectomy; Locomotion; Motor Activity; Muscles; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Spinal Cord; Time Factors | 1993 |
Involvement of excitatory amino acids in the activity of swallowing-related neurons of the ventro-lateral medulla.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Dipeptides; Electric Stimulation; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Different proportions of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Bicuculline; Cerebellum; Cytoplasmic Granules; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kinetics; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons; Neurons, Afferent; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
A developmental decrease in NMDA-mediated spontaneous firing in cultured rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Electrophysiology; Female; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
Glutamate neurons in hypothalamus regulate excitatory transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus; Microscopy, Electron; N-Methylaspartate; Neurites; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
High-affinity kainate binding sites in living slices of rat neocortex: characterization and regulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Veratridine | 1993 |
Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Cell Line; Cells, Cultured; Diazoxide; Diuretics; Electric Stimulation; Evoked Potentials; Hippocampus; Humans; Kainic Acid; Membrane Potentials; Molecular Structure; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Structure-Activity Relationship; Synapses; Time Factors | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord.
Topics: Animals; Capsaicin; Female; GABA Antagonists; Long-Term Potentiation; Male; N-Methylaspartate; Neurons, Afferent; Quinoxalines; Rats; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of dextromethorphan in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dextromethorphan; Electric Stimulation; Electromyography; H-Reflex; Injections, Intraperitoneal; Injections, Spinal; Male; Muscle Relaxation; Muscles; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reflex, Stretch | 1993 |
Cardiovascular responses to global cerebral ischemia: role of excitatory amino acids in the ventrolateral medullary pressor area.
Topics: Acetylcholine; Amino Acids; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Blood Pressure; Brain Ischemia; Dose-Response Relationship, Drug; Glutamates; Heart Rate; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Muscimol; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Vasopressin; Vasopressins | 1993 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1996 |
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus | 1996 |
A comparison of the effect of halothane on N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated excitatory synaptic transmission in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Halothane; Hippocampus; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.
Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating | 1996 |
Effects of excitatory amino acid receptor agonists and antagonists on the secretion of melatonin, luteinizing hormone and prolactin in the ram.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Luteinizing Hormone; Male; Melatonin; N-Methylaspartate; Photoperiod; Prolactin; Quinoxalines; Radioimmunoassay; Sheep | 1993 |
Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Quinoxalines | 1996 |
N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor antagonism reduces Fos-like immunoreactivity in central trigeminal neurons after corneal stimulation in the rat.
Topics: Animals; Cornea; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunohistochemistry; Injections, Intraventricular; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Nociceptors; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal | 1996 |
Endogenous gamma-L-glutamylglutamate is a partial agonist at the N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebellum; Dipeptides; Drug Synergism; Glutamates; Glutamic Acid; Glycine; Magnesium; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Glutamate receptor regulation of rat nucleus accumbens neurons in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1996 |
N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Male; N-Methylaspartate; Neurons; Peripheral Nerve Injuries; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
The mechanism by which NBQX enhances NMDA currents in retinal ganglion cells.
Topics: Animals; Chlorides; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Light; N-Methylaspartate; Neurotransmitter Agents; Picrotoxin; Quinoxalines; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Sucrose; Synaptic Transmission; Urodela | 1996 |
N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; N-Methylaspartate; Prosencephalon; Protein Precursors; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1995 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
Functional partial agonism at ionotropic excitatory amino acid receptors.
Topics: Alanine; Animals; Binding, Competitive; Cerebral Cortex; Dinucleoside Phosphates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Models, Neurological; N-Methylaspartate; Propionates; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate | 1996 |
Determination of intracellular Ca2+ concentration can be a useful tool to predict neuronal damage and neuroprotective properties of drugs.
Topics: Amantadine; Analysis of Variance; Animals; Biomarkers; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kinetics; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Cyanide; Telencephalon; Time Factors | 1996 |
Differential effects of five glycine site antagonists on NMDA receptor desensitisation.
Topics: Animals; Benzothiadiazines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine | 1996 |
Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Isotopes; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Deferoxamine; Deuterium; Dizocilpine Maleate; Fetus; Gas Chromatography-Mass Spectrometry; Glucose; Hydrogen Peroxide; Iron; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Pentose Phosphate Pathway; Putamen; Quinoxalines; Rats | 1996 |
Studies of synaptic transmission in vivo: indirect versus direct effects of (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid/kainate antagonists on rat spinal sensory responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Iontophoresis; Male; Microelectrodes; N-Methylaspartate; Neurons, Afferent; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord; Synaptic Transmission | 1996 |
Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biguanides; Brain Mapping; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Kynurenic Acid; Lung; Male; N-Methylaspartate; Nerve Fibers; Neurons; Pressoreceptors; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus; Vagus Nerve | 1996 |
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1997 |
A new non-NMDA antagonist modifies the local cerebral glucose utilization in kainate-induced generalized seizure.
Topics: Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures | 1997 |
Presynaptic control of subunit composition of NMDA receptors mediating synaptic plasticity.
Topics: Animals; Bicuculline; Cells, Cultured; Coculture Techniques; Embryo, Mammalian; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kinetics; Macromolecular Substances; Magnesium; N-Methylaspartate; Neuronal Plasticity; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Polymerase Chain Reaction; Presynaptic Terminals; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
Estimation of the relative potency of two glycine antagonists on NMDA-induced depolarizations in BRSC and ARCS.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 1997 |
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate.
Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Consciousness; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; N-Methylaspartate; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1997 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Regulation of gonadotropin-releasing hormone and luteinizing hormone secretion by AMPA receptors. Evidence for a physiological role of AMPA receptors in the steroid-induced luteinizing hormone surge.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Ovariectomy; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines.
Topics: Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Isomerism; Models, Chemical; N-Methylaspartate; Phencyclidine; Quinoxalines; Radioligand Assay; Rats; Receptors, AMPA; Structure-Activity Relationship; Tyrosine | 1997 |
Measurement of intracellular free zinc in living cortical neurons: routes of entry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Ionophores; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Neurons; Nimodipine; Quinoxalines; Sodium-Calcium Exchanger; Zinc | 1997 |
Cardiovascular effects of nitric oxide and N-methyl-D-aspartate receptors in the nucleus tractus solitarii of rats.
Topics: Animals; Arginine; Blood Pressure; Brain Mapping; Brain Stem; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1997 |
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission.
Topics: Animals; Arachidonic Acids; Brain; Calcium; Calcium Channel Blockers; Cannabinoids; Cerebellum; Cerebral Cortex; Dronabinol; Endocannabinoids; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Oocytes; Pertussis Toxin; Picrotoxin; Polyunsaturated Alkamides; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Virulence Factors, Bordetella; Wasp Venoms; Xenopus laevis | 1998 |
Activation of non-NMDA receptors stimulates acetylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1998 |
Presynaptic 5-HT3 receptors evoke an excitatory response in dorsal vagal preganglionic neurones in anaesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Cadmium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ganglia, Autonomic; Iontophoresis; Magnesium; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Vagus Nerve | 1998 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
The effect of excitatory aminoacids on GABA release from mediobasal hypothalamus of female rats.
Topics: Animals; Depression, Chemical; Diestrus; Drug Implants; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Interneurons; Kainic Acid; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide Synthase; Ovariectomy; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1998 |
Characterization of temperature rise of the brain and the rectum following intracerebroventricular administration of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Body Temperature; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indomethacin; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rectum | 1998 |
Screening of receptor antagonists using agonist-activated patch clamp detection in chemical separations.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Electrophoresis, Capillary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Ion Channels; Mathematics; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Cell Surface | 1998 |
Genesis of spontaneous rhythmic motor patterns in the lumbosacral spinal cord of neonate mouse.
Topics: Animals; Animals, Newborn; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Locomotion; Magnesium; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Periodicity; Pregnancy; Quinoxalines; Spinal Cord | 1998 |
Low-affinity kainate receptors and long-lasting depression of NMDA-receptor-mediated currents in rat superficial dorsal horn.
Topics: Action Potentials; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Glutamic Acid; Indoles; Ion Channel Gating; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Neuroprotective Agents; Oximes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1998 |
Reevaluation of ACEA 1021 as an antagonist at the strychnine-insensitive glycine site of the N-methyl-D-aspartate receptor.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neocortex; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 1998 |
Role of excitatory amino acid pathways in control of gonadotrophin secretion in adult female rats sterilized by neonatal administration of oestradiol or testosterone.
Topics: Animals; Animals, Newborn; Anovulation; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Kainic Acid; Luteinizing Hormone; N-Methylaspartate; Ovariectomy; Quinoxalines; Rats; Rats, Wistar; Testosterone | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Infusional high-dose application of the calcium-channel-blocking and antiglutamatergic agent caroverine in the treatment of alcohol withdrawal (DSM-III-R 291.80).
Topics: Adult; Alcohols; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Female; Humans; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged; N-Methylaspartate; Pilot Projects; Quinoxalines; Substance Withdrawal Syndrome | 1998 |
Calcium influx via ionotropic glutamate receptors causes long lasting inhibition of metabotropic glutamate receptor-coupled phosphoinositide hydrolysis.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Hydrolysis; Kainic Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium Fluoride | 1998 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.
Topics: Animals; Central Nervous System Depressants; Diazepam; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; GABA Modulators; Hypnotics and Sedatives; Indoles; Male; Midazolam; Morphine; N-Methylaspartate; Narcotics; Pentobarbital; Phencyclidine; Pregnanolone; Quinoxalines; Rats; Rats, Long-Evans; Serotonin Receptor Agonists; Water | 1997 |
Sexual differences in the role of kainate receptors in controlling gonadotrophin secretion in prepubertal rats.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Orchiectomy; Ovariectomy; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sex Factors; Sexual Maturation | 1998 |
Assessing the roles of glutamatergic and cholinergic synaptic drive in the control of fictive swimming frequency in young Xenopus tadpoles.
Topics: Animals; Cholinergic Fibers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Larva; N-Methylaspartate; Neural Inhibition; Quinoxalines; Receptors, Nicotinic; Swimming; Synapses; Xenopus | 1998 |
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture Techniques; Cytosol; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Microscopy, Fluorescence; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Sodium; Veratridine | 1998 |
Coexistence of glutamate and acetylcholine in the developing motoneurons.
Topics: Acetylcholine; Animals; Cells, Cultured; Choline O-Acetyltransferase; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Growth Cones; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nervous System; Patch-Clamp Techniques; Quinoxalines; Receptors, Glutamate; Synapses; Xenopus laevis | 1998 |
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Animal; Electroshock; Hydrobromic Acid; Hydrochloric Acid; Hydroxy Acids; Inhibitory Concentration 50; Mice; N-Methylaspartate; Organophosphonates; Quinoxalines | 1999 |
Regulation of vasopressin release by ionotropic glutamate receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Hypothalamo-Hypophyseal System; Kainic Acid; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 1998 |
Multiple types of spontaneous excitatory synaptic currents in salamander retinal ganglion cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Convulsants; Darkness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Larva; N-Methylaspartate; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Synapses; Synaptic Vesicles | 1999 |
Increase in vasopressin concentration and cardiodepressant activity in the blood dialysates after NMDA and hypertonic saline administration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Blood Physiological Phenomena; Dialysis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart; Male; N-Methylaspartate; Osmolar Concentration; Quinoxalines; Rats; Rats, Inbred BUF; Rats, Wistar; Saline Solution, Hypertonic | 1998 |
Ionotropic glutamate receptors in isolated horizontal cells of the rabbit retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
Vagally-regulated gastric motor activity: evidence for kainate and NMDA receptor mediation.
Topics: Animals; Atropine; Blood Pressure; Brain Stem; Bronchodilator Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gastrointestinal Motility; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stomach; Vagus Nerve | 1999 |
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Retina | 1999 |
AMPA/kainate-related mechanisms contribute to convulsant and proconvulsant effects of 3-nitropropionic acid.
Topics: Animals; Anticonvulsants; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraventricular; Male; Mice; Mitochondria; N-Methylaspartate; Nitro Compounds; Propionates; Quinoxalines; Receptors, AMPA | 1999 |
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Lighting; Male; Mesocricetus; Microinjections; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Synaptic Transmission | 1999 |
Effects of puerarin against glutamate excitotoxicity on cultured mouse cerebral cortical neurons.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoflavones; Kainic Acid; Kynurenic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Glutamate | 1998 |
Differential roles of ionotropic glutamate receptors in canine medullary inspiratory neurons of the ventral respiratory group.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Inhalation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Agonists; Female; Kainic Acid; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Splanchnic Nerves; Viscera | 1999 |
Role of glutamate receptors in transmission of vagal cardiac input to neurones in the nucleus tractus solitarii in dogs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dogs; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart; In Vitro Techniques; Microelectrodes; N-Methylaspartate; Neurons; Neurons, Afferent; Quinoxalines; Receptors, Glutamate; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 1999 |
NMDA receptor-mediated control of GABA release from neurointermediate lobes of female and male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Ovariectomy; Pituitary Gland, Posterior; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Multiple and opposing roles of cholinergic transmission in the main olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Calcium; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Kinetics; Magnesium; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Receptors, GABA-A; Receptors, Nicotinic; Synapses | 1999 |
Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bee Venoms; Cats; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; N-Methylaspartate; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Homocysteine; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1999 |
Stimulation of NMDA and AMPA receptors in the rat nucleus basalis of Meynert affects sleep.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Nucleus of Meynert; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sleep; Sleep Stages; Wakefulness | 1999 |
Intermediate zone cells express calcium-permeable AMPA receptors and establish close contact with growing axons.
Topics: Action Potentials; Animals; Axons; Benzodiazepines; Biological Transport; Calbindins; Calcium; Cerebral Cortex; Cobalt; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gestational Age; In Vitro Techniques; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; N-Methylaspartate; Neurites; Neurons; Prosencephalon; Quinoxalines; Receptors, AMPA; S100 Calcium Binding Protein G; Tetrodotoxin | 2000 |
Cholecystokinin (CCK) increases GABA release in the rat anterior nucleus accumbens via CCK(B) receptors located on glutamatergic interneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholecystokinin; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stimulation, Chemical; Tetrodotoxin | 2000 |
Participation of NMDA and kainate receptors of paraventricular nucleus in cardiovascular responses to glutamate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Kainic Acid; Male; Microinjections; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
A method for evaluating chemical selectivity of agonists for glutamate receptor channels incorporated in liposomes based on an agonist-induced ion flux measured by ion-selective electrodes.
Topics: Amino Acids, Dicarboxylic; Animals; Calcium; Calibration; Chromatography, Thin Layer; Electrodes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Liposomes; N-Methylaspartate; Potentiometry; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium | 1999 |
Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Isoxazoles; N-Methylaspartate; Propionates; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Behavioural motor effects of MK-801 and DNQX parenteral administration in adult cats: dose-response analysis. Modulatory role of dopaminergic D1 and D2 antagonists on MK-801 induced motor behaviours.
Topics: Animals; Behavior, Animal; Benzazepines; Cats; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine D1; Sulpiride | 2000 |
Ionotropic glutamate receptor-mediated responses in the rat primary somatosensory cortex evoked by noxious and innocuous cutaneous stimulation in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Male; N-Methylaspartate; Neurons; Pain; Piperazines; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Skin; Somatosensory Cortex; Synapses; Time Factors | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Blocking the trigeminal EPSP in rat abducens motoneurons in vivo with the AMPA antagonists NBQX and GYKI 53655.
Topics: Abducens Nerve; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Trigeminal Nerve | 2000 |
Superoxide dismutase activity and the effects of NBQX and CPP on lipid peroxidation in experimental spinal cord injury.
Topics: Animals; Excitatory Amino Acid Antagonists; Lipid Peroxidation; Male; Malondialdehyde; N-Methylaspartate; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase | 2000 |
Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chick Embryo; Dendrites; Excitatory Amino Acid Antagonists; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Retina; Retinal Ganglion Cells; rho GTP-Binding Proteins; Synaptic Transmission; Tetrodotoxin; Transfection | 2000 |
Calcium influx through NMDA receptors directly evokes GABA release in olfactory bulb granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Calcium; Calcium Channels; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 2000 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Chick Embryo; Excitatory Amino Acid Antagonists; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Monophosphate; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Thionucleotides | 2000 |
Motor stimulation following bilateral injection of the group-I metabotropic glutamate receptor agonist into the dorsal striatum of rats: evidence against dependence on ionotropic glutamate receptors.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Microinjections; Motor Activity; N-Methylaspartate; Neostriatum; Neurons; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Stimulation, Chemical | 2000 |
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT(2C) and 5-HT(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylamines; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; N-Methylaspartate; Neocortex; Nitric Oxide; Nitroarginine; Oxadiazoles; Piperazines; Pyridines; Quinoxalines; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Trazodone | 2000 |
Effect of norepinephrine receptors on trigeminal rhythm generation in newborn rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Brimonidine Tartrate; Idazoxan; Mastication; Motor Neurons; N-Methylaspartate; Neural Pathways; Norepinephrine; Organ Culture Techniques; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Trigeminal Nuclei | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Techniques; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Pregnancy; Quinoxalines; Rats; Rats, Inbred Lew; Signal Transduction; Vasodilator Agents | 2000 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Blockade of AMPA/kainate receptors can either decrease or increase the survival of cultured neocortical cells depending on the stage of maturation.
Topics: Animals; Benzodiazepines; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Kainic Acid; N-Methylaspartate; Neocortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2001 |
Enhanced NMDA receptor activity in retinal inputs to the rat suprachiasmatic nucleus during the subjective night.
Topics: Animals; Biological Clocks; Circadian Rhythm; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Light; Male; N-Methylaspartate; Neurons; Optic Chiasm; Optic Nerve; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 2001 |
The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures.
Topics: Animals; Coloring Agents; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Propidium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Staining and Labeling | 2001 |
Structure-activity relationships of 1,4-dihydro-(1H,4H)-quinoxaline-2,3-diones as N-methyl-D-aspartate (glycine site) receptor antagonists. 1. Heterocyclic substituted 5-alkyl derivatives.
Topics: Aminoquinolines; Animals; Cell Membrane; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glycine; Indicators and Reagents; Mice; Models, Molecular; Motor Activity; N-Methylaspartate; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Synthesis, ionotropic glutamate receptor binding affinity, and structure-activity relationships of a new set of 4,5-dihydro-8-heteroaryl-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates analogues of TQX-173.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ligands; Male; Mice; N-Methylaspartate; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Structure-Activity Relationship; Synaptic Membranes; Triazines | 2001 |
Glomerulus-specific synchronization of mitral cells in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Periodicity; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell | 2001 |
The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats.
Topics: Animals; Blood Pressure; Bradycardia; Cats; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; Heart Rate; Hypertension; Indazoles; Male; Medulla Oblongata; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Signaling; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Indoles; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Thapsigargin | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Different action of memantine and caroverine on glutamatergic transmission in the mammalian cochlea.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Dopamine Agents; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Memantine; N-Methylaspartate; Neurons, Afferent; Quinoxalines | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Pyrrolylquinoxalinediones carrying a piperazine residue represent highly potent and selective ligands to the homomeric kainate receptor GluR5.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ligands; Mice; Molecular Structure; N-Methylaspartate; Piperazines; Quinoxalines; Receptors, Kainic Acid; Seizures; Structure-Activity Relationship; Substrate Specificity | 2002 |
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Consciousness; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Kynurenic Acid; Medulla Oblongata; Microinjections; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Respiratory Mechanics | 2002 |
Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Brimonidine Tartrate; Calcium; Cell Culture Techniques; Cell Survival; Dose-Response Relationship, Drug; Fura-2; Glutamic Acid; Metoprolol; N-Methylaspartate; Neuroglia; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Retina; Retinal Ganglion Cells; Timolol | 2002 |
Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Glutamic Acid; Kainic Acid; N-Methylaspartate; Osteoblasts; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; Skull | 2002 |
Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus accumbens.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats | 2002 |
The epileptogenic effect of seizures induced by hypoxia: the role of NMDA and AMPA/KA antagonists.
Topics: Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Mice; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 2003 |
Effects of intra-accumbens focal administrations of glutamate antagonists on object recognition memory in mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Mapping; Discrimination Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Form Perception; Male; Mental Recall; Mice; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Quinoxalines | 2003 |
Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Laminectomy; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Urethra | 2003 |
Perturbations in three medullary nuclei enhance fractionated breathing in awake goats.
Topics: Animals; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Inhalation; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Respiratory Mechanics; Respiratory Physiological Phenomena; Sleep | 2003 |
Pharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man.
Topics: Adolescent; Adult; Animals; Bile; Binding Sites; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Central Nervous System; Dogs; Glycine; Humans; Male; Middle Aged; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Distribution | 2003 |
Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
Topics: Animals; Autoradiography; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Male; Melatonin; Microinjections; N-Methylaspartate; Nuclear Proteins; Pineal Gland; Quinoxalines; Radioimmunoassay; RNA, Messenger; Suprachiasmatic Nucleus; Valine | 2003 |
MAC reduction after intrathecal coadministration of GABA(A) agonist and glutamate antagonist in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Agonists; Imidazoles; Injections, Spinal; Male; Methyl Ethers; Muscimol; N-Methylaspartate; Pain; Pulmonary Alveoli; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sevoflurane | 2003 |
Characterization of spontaneous synaptic transmission in rat medial vestibular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Kinetics; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Strychnine; Synaptic Transmission; Vestibular Nuclei | 2003 |
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).
Topics: Amnesia; Animals; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kynurenic Acid; Male; Mice; N-Methylaspartate; Nootropic Agents; Piperazines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2003 |
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Corpus Striatum; Drug Administration Schedule; Fungicides, Industrial; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Remoxipride; Substance Withdrawal Syndrome; Time Factors; Triazoles | 2004 |
NMDA receptors in nucleus tractus solitarii are linked to soluble guanylate cyclase.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoquinolines; Animals; Baroreflex; Biotransformation; Blood Pressure; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; In Vitro Techniques; Male; Microinjections; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Stereotaxic Techniques | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.
Topics: Amino Acids; Animals; Biguanides; Binding Sites; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Riluzole | 2004 |
Schaffer collateral and perforant path inputs activate different subtypes of NMDA receptors on the same CA1 pyramidal cell.
Topics: Animals; Excitatory Postsynaptic Potentials; N-Methylaspartate; Perforant Pathway; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Glutamatergic synaptic transmission participates in generating the hippocampal EEG.
Topics: Animals; Cerebral Ventricles; Electroencephalography; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Injections, Intraventricular; Kinetics; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Long-Evans; Synaptic Transmission | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
The soluble guanylyl cyclase inhibitor ODQ, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, dose-dependently reduces the threshold for isoflurane anesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Isoflurane; Male; N-Methylaspartate; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Baclofen; Brimonidine Tartrate; Calcium; Cyclic AMP; Dopamine Agonists; Drug Interactions; Excitatory Amino Acid Agonists; GABA Agonists; GTP-Binding Protein alpha Subunits, Gi-Go; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Quinoxalines; Quinpirole; Radioimmunoassay; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists | 2004 |
Protection of auditory function against noise trauma with local caroverine administration in guinea pigs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Threshold; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hearing Loss, Noise-Induced; Male; N-Methylaspartate; Noise; Quinoxalines; Random Allocation; Receptors, Glutamate | 2004 |
BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Phenols; Piperidines; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2005 |
Oxytocin content in the venous blood outflowing from the vicinity of the cavernous sinus and from the femoral vein.
Topics: Animals; Cavernous Sinus; Femoral Vein; Hypoxia; Male; N-Methylaspartate; Oxytocin; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2004 |
Effects of levetiracetam on the production of nitric oxide--an in vivo study.
Topics: Analysis of Variance; Animals; Anticonvulsants; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Levetiracetam; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piracetam; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2005 |
Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neuronal Plasticity; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures.
Topics: Animals; Dendrites; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Kinetics; Mice; N-Methylaspartate; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Tetrodotoxin | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Lignans; Mice; N-Methylaspartate; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Sodium | 2005 |
Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA.
Topics: Animals; Animals, Newborn; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Hippocampus; Indazoles; Ion Transport; Mitochondria; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Oxygen; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Compounds; Thiazepines | 2005 |
Silent synapses in a thalamo-cortical circuit necessary for song learning in zebra finches.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Finches; In Vitro Techniques; Learning; Lysine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Patch-Clamp Techniques; Quinoxalines; Synapses; Thalamus; Vocalization, Animal | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Binding Sites; Brain; Calcium; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Motor Activity; N-Methylaspartate; Neurons; Polyvinyls; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Time Factors | 2005 |
Tunicamycin decreases the probability of single-channel openings for N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Probability; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tunicamycin | 2006 |
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Benzoxazoles; Calcium Channel Blockers; Cocaine; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lysine; Male; Motor Activity; N-Methylaspartate; Naphthyridines; Neuronal Plasticity; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Thionucleotides; Time Factors; Tyrosine 3-Monooxygenase; Urea; Ventral Tegmental Area | 2006 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Estrogens; Female; Glutamic Acid; N-Methylaspartate; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Urethra | 2006 |
Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum.
Topics: Animals; Cerebellum; Cerebrovascular Circulation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Hydrazines; In Vitro Techniques; Male; Microcirculation; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.
Topics: Animals; Animals, Newborn; Cell Line, Transformed; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Transfection | 2007 |
Reduced presynaptic efficiency of excitatory synaptic transmission impairs LTP in the visual cortex of BDNF-heterozygous mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Calcium; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Synaptic Transmission; Time Factors; Visual Cortex | 2006 |
Differential regulation of glutamate receptor-mediated BDNF mRNA expression in the cerebellum and its defects in stargazer mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium Channels; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; In Situ Hybridization; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neurons; Protein Binding; Quinoxalines; Receptors, Glutamate; RNA, Messenger; Time Factors | 2007 |
Suprachiasmatic modulation of noradrenaline release in the ventrolateral preoptic nucleus.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; Preoptic Area; Quinoxalines; Rats; Suprachiasmatic Nucleus; Yohimbine | 2007 |
Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors.
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Mice; Mice, Knockout; Mutation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Piperidines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Time Factors | 2007 |
Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP.
Topics: Animals; Anisomycin; Brain Diseases; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Ischemic Preconditioning; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxadiazoles; Protein Synthesis Inhibitors; Quinoxalines | 2007 |
Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2008 |
Retinocollicular synapse maturation and plasticity are regulated by correlated retinal waves.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Retina; Superior Colliculi; Synapses; Synaptic Transmission; Visual Pathways | 2008 |
Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences.
Topics: Animals; Animals, Newborn; Dendritic Spines; Dizocilpine Maleate; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; Female; Hypothalamus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Silver Staining | 2008 |
Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Signaling; Disease Models, Animal; Excitatory Amino Acid Agonists; Glaucoma; Male; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Rabbits; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Rolipram | 2008 |
Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1).
Topics: Actin Depolymerizing Factors; Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysics; Cells, Cultured; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; p21-Activated Kinases; Patch-Clamp Techniques; Quinoxalines; Synapses | 2009 |
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2008 |
Differential inhibition of globus pallidus neurons by electrical or chemical stimulation of the striatum.
Topics: Action Potentials; Animals; Biophysics; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agents; Globus Pallidus; Glutamic Acid; Male; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurons; Quinoxalines; Rats; Rats, Wistar; Stimulation, Chemical | 2008 |
Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Depressive Disorder; Excitatory Amino Acid Antagonists; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming | 2008 |
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase.
Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures | 2009 |
Cardiovascular and thermal responses evoked from the periaqueductal grey require neuronal activity in the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Body Temperature Regulation; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; Heart Rate; Hypothalamus; Male; Motor Activity; Muscimol; N-Methylaspartate; Neural Pathways; Paraventricular Hypothalamic Nucleus; Periaqueductal Gray; Quinoxalines; Rats; Rats, Sprague-Dawley | 2009 |
Homeostatic presynaptic suppression of neuronal network bursts.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Green Fluorescent Proteins; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; N-Methylaspartate; Nerve Net; Neurons; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptosomal-Associated Protein 25; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2009 |
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2009 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Topiramate antagonizes NMDA- and AMPA-induced seizure-like activity in planarians.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; N-Methylaspartate; Neuroprotective Agents; Planarians; Quinoxalines; Seizures; Topiramate | 2009 |
Selective expression of ligand-gated ion channels in L5 pyramidal cell axons.
Topics: Animals; Animals, Newborn; Axons; Calcium; Calcium Signaling; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Indoles; Ion Channel Gating; Ion Channels; Iontophoresis; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley | 2009 |
Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis.
Topics: Action Potentials; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Chi-Square Distribution; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Interneurons; Mice; Mice, Transgenic; Motor Neurons; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Psychomotor Performance; Quinoxalines; Reaction Time; Reflex; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Synapses | 2009 |
N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Inosine; N-Methylaspartate; Neurons; Piperidines; Purines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2009 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Hippocampus; Imidazoles; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurons; p38 Mitogen-Activated Protein Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus.
Topics: Animals; CA1 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Electrochemical Techniques; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microelectrodes; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Nimodipine enhancement of alpha2 adrenergic modulation of NMDA receptor via a mechanism independent of Ca2+ channel blocking.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Excitatory Amino Acid Agonists; Injections; Male; Microscopy, Confocal; N-Methylaspartate; Nimodipine; Patch-Clamp Techniques; Quinoxalines; Rabbits; Rats; Rats, Inbred BN; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retinal Diseases; Retinal Ganglion Cells; Vitreous Body | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biological Clocks; Brain Stem; Cadmium Chloride; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Glycyrrhetinic Acid; Humans; In Vitro Techniques; Larva; Models, Biological; Movement; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Periodicity; Pyridazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming; Xenopus | 2010 |
mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Electric Stimulation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Knockout; Models, Biological; N-Methylaspartate; Piperidines; Pyramidal Cells; Pyridines; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thiazoles; Time Factors; Visual Cortex | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Topics: Animals; Azabicyclo Compounds; Cells, Cultured; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; HeLa Cells; Hippocampus; Humans; N-Methylaspartate; Neurons; Organophosphonates; Phenols; Piperidines; Protein Subunits; Pseudopodia; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2012 |
Glutamate spillover promotes the generation of NMDA spikes.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Biophysics; Calcium; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Drug Synergism; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Indoles; Male; Mice; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Statistics, Nonparametric | 2011 |
Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Homeostasis; N-Methylaspartate; Neurons; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2012 |
Dopamine-glutamate interplay in the ventral striatum modulates spatial learning in a receptor subtype-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Habituation, Psychophysiologic; Learning; Male; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine; Space Perception; Sulpiride | 2012 |
What a nostril knows: olfactory nerve-evoked AMPA responses increase while NMDA responses decrease at 24-h post-training for lateralized odor preference memory in neonate rat.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Conditioning, Psychological; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Functional Laterality; In Vitro Techniques; Learning; Male; N-Methylaspartate; Nose; Odorants; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell; Tetrodotoxin | 2012 |
AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test.
Topics: Acetylcysteine; alpha-Methyltyrosine; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fenclonine; Hindlimb Suspension; Locomotion; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Receptors, AMPA | 2012 |
Ionotropic glutamate receptors in hypothalamic paraventricular and supraoptic nuclei mediate vasopressin and oxytocin release in unanesthetized rats.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; N-Methylaspartate; Oxytocin; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Vasopressins | 2012 |
Salsolinol facilitates glutamatergic transmission to dopamine neurons in the posterior ventral tegmental area of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Central Nervous System Depressants; Dopaminergic Neurons; Ethanol; Excitatory Amino Acid Antagonists; Isoquinolines; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Synaptic Transmission; Ventral Tegmental Area | 2012 |
Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons.
Topics: Animals; Blotting, Western; Calcium Signaling; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sodium-Calcium Exchanger | 2012 |
Muscarinic control of AMPA receptor responsiveness in mouse spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarinic Agonists; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, Muscarinic; Spinal Cord | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Cell Adhesion Molecules, Neuronal; Cell Line, Transformed; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Long-Term Potentiation; Membrane Proteins; MicroRNAs; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Structure, Tertiary; Quinoxalines; Rats; RNA Interference; Statistics, Nonparametric; Stereotaxic Techniques; Transduction, Genetic; Transfection | 2012 |
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.
Topics: A Kinase Anchor Proteins; Action Potentials; Analysis of Variance; Animals; Biophysics; Calcineurin; Calcium; Cells, Cultured; Dendritic Spines; Disks Large Homolog 4 Protein; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guanylate Kinases; Hippocampus; Immunoprecipitation; In Vitro Techniques; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Phosphorylation; Quinoxalines; Receptors, AMPA; Serine; Silver Staining; Sodium Channel Blockers; Subcellular Fractions; Synapses; Tetrodotoxin | 2012 |
Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Corpus Striatum; Dopamine Antagonists; Electric Stimulation; Ethanol; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Food Preferences; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Sucrose; Sulpiride; Sweetening Agents; Synaptosomes; Up-Regulation | 2012 |
Low doses of the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, induces social facilitation in adolescent male rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Social Facilitation | 2013 |
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Citalopram; Cyclopropanes; Imipramine; Immobility Response, Tonic; Male; Mice; Milnacipran; Morpholines; Motor Activity; N-Methylaspartate; Oxazines; Quinoxalines; Reboxetine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2013 |
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat.
Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus | 2014 |
Combined blockade of NMDA and AMPA receptors prevents acute kainate seizures and chronic kainate lethality in rats.
Topics: Adamantane; Amines; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intramuscular; Kainic Acid; Male; Memantine; N-Methylaspartate; Neuroprotective Agents; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Analysis | 2014 |
Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Differentiation; Cell Line; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophysiology; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Quinoxalines; Receptors, Ionotropic Glutamate | 2014 |
Efficient, complete deletion of synaptic proteins using CRISPR.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Humans; In Vitro Techniques; Luminescent Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Red Fluorescent Protein; RNA; Synapses; Synaptophysin | 2014 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |
Prefrontal Cortex Drives Distinct Projection Neurons in the Basolateral Amygdala.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Basolateral Nuclear Complex; Channelrhodopsins; Cholera Toxin; Dependovirus; Excitatory Postsynaptic Potentials; Genetic Vectors; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2017 |
NMDARs contribute to the facial stimuli-evoked mossy fiber-granule cell synaptic transmission in vivo in mice.
Topics: Animals; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Physical Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine; Vibrissae | 2020 |