quinoxalines has been researched along with morphine in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.00) | 18.7374 |
| 1990's | 26 (52.00) | 18.2507 |
| 2000's | 13 (26.00) | 29.6817 |
| 2010's | 9 (18.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jansen van't Land, C; van der Laan, JW | 1 |
| Osborne, PB; Pan, ZZ; Williams, JT | 1 |
| Lundberg, JM; Martling, CR; Matran, R | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Lester, BR; Sun, Z; Wilcox, GL; Wu, HH | 1 |
| Zvartau, EE | 1 |
| Honoré, T; Jacobsen, P; Swedberg, MD | 1 |
| Galligan, JJ | 1 |
| Ault, B; Hildebrand, LM | 1 |
| Cai, SX; Keana, JF; Kwon, IS; Lutfy, K; Shen, KZ; Weber, E; Woodward, RM | 1 |
| Mao, J; Mayer, DJ; Price, DD | 1 |
| Calvo, P; Fernández-López, A; Gómez, T; Revilla, V; Soria, C | 1 |
| Galbiati, M; Martini, L; Messi, E; Zanisi, M | 1 |
| Keana, JF; Lutfy, K; Weber, E; Woodward, RM | 1 |
| Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Keana, JF; Kwon, IS; Lutfy, K; Marek, P; Sadowski, B; Weber, E | 1 |
| Lutfy, K; Shen, KZ; Weber, E; Woodward, RM | 1 |
| Brown, G; Jackson, A; Stephens, DN | 1 |
| Chaplan, SR; Malmberg, AB; Yaksh, TL | 1 |
| Ingram, S; McCleskey, EW; Wilding, TJ; Williams, JT | 1 |
| Kitto, KF; Limbird, LE; MacMillan, LB; Stone, LS; Wilcox, GL | 1 |
| Calcutt, NA; Chaplan, SR | 1 |
| Abysique, A; Bouvier, M; Orsoni, P | 1 |
| Auberson, S; Kordestani, RK; Lacroix, JS; Lundberg, JM | 1 |
| Bowen, CA; Gatto, GJ; Grant, KA | 1 |
| Doan, P; Lutfy, K; Nugyen, M; Weber, E | 1 |
| Doan, P; Lutfy, K; Weber, E | 1 |
| Han, S; Jia, YS; Ju, G; Liu, QS | 1 |
| Hall, SR; Jhamandas, K; Milne, B; Sullivan, ME | 1 |
| Nishiyama, T | 1 |
| Forray, MI; Fuentealba, JA; Gysling, K | 1 |
| Kratzer, U; Schmidt, WJ | 1 |
| Blackburn-Munro, G; Bomholt, SF; Erichsen, HK | 1 |
| Dang, VC; Williams, JT | 1 |
| Wang, HL; Wang, HS; Wu, WR; Xiang, XH; Zhao, Y | 1 |
| Cao, DY; Guo, Y; Wang, HL; Wang, HS; Wu, WR; Xiang, XH; Zhao, Y | 1 |
| Aase, DM; Atkinson, DM; Gewirtz, JC; Harris, AC | 1 |
| Gheitasi, IP; Haghparast, A; Lashgari, R | 1 |
| Brock, SC; Tonussi, CR | 1 |
| Jones, TL; Malkmus, SA; Nagakura, Y; Sorkin, L; Yaksh, TL | 1 |
| Cunha, FQ; Duarte, DB; Ferrari, LF; Ferreira, SH; Funez, MI; Lorenzetti, BB; Parada, CA; Sachs, D | 1 |
| Biala, G; Budzynska, B; Staniak, N | 1 |
| Biala, G; Staniak, N | 1 |
| Ahmad, T; Bishop, SF; De Jaeger, X; Laviolette, SR; Lyons, D; Ng, GA | 1 |
| Cunningham, CS; McMahon, LR | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Gursoy, S; Ozdemir, E | 1 |
| Chen, Y; Cui, J; Fu, L; Gong, N; Li, TF; Li, XY; Lu, J; Wang, YC; Wang, YX; Xie, D; Xie, J | 1 |
| Chen, M; Dong, Y; Lai, B; Song, J; Zheng, P | 1 |
| Cui, C; Li, Y; Sun, L; Sun, X; Wang, N; Wang, X | 1 |
| Chen, X; Feng, M; Liu, T; Wan, L; Yao, W; Zhang, B; Zhang, C; Zhang, Y | 1 |
50 other study(ies) available for quinoxalines and morphine
| Article | Year |
|---|---|
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Doxazosin; Drug Implants; Eating; Food; Male; Morphine; Morphine Dependence; Motor Activity; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Opioid actions on single nucleus raphe magnus neurons from rat and guinea-pig in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Medulla Oblongata; Morphine; Neurons; Quinoxalines; Rats | 1990 |
Inhibition of cholinergic and non-adrenergic, non-cholinergic bronchoconstriction in the guinea pig mediated by neuropeptide Y and alpha 2-adrenoceptors and opiate receptors.
Topics: Animals; Antihypertensive Agents; Autonomic Nervous System; Brimonidine Tartrate; Bronchi; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Neuropeptide Y; Parasympathetic Nervous System; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Opioid; Sympathomimetics | 1989 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Antinociception following implantation of mouse B16 melanoma cells in mouse and rat spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Catecholamines; Cell Transplantation; Desipramine; Dioxanes; Idazoxan; Injections, Spinal; Male; Melanoma, Experimental; Mice; Mice, Inbred ICR; Morphine; Naloxone; Neoplasm Transplantation; Nociceptors; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Substance P; Transplantation, Heterotopic | 1994 |
Subchronic morphine increases amphetamine-induced potentiation of brain stimulation reward: reversal by DNQX.
Topics: Amphetamine; Animals; Behavior, Animal; Conditioning, Operant; Glutamic Acid; Male; Morphine; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains; Reward; Time Factors | 1995 |
Anticonvulsant, anxiolytic and discriminative effects of the AMPA antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX).
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Excitatory Amino Acid Antagonists; Female; Male; Mice; Mice, Inbred DBA; Morphine; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures | 1995 |
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by mu opioid and alpha-2 adrenergic agonists in guinea pig ileum.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Choline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Neurotransmitter Uptake Inhibitors; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Opioid, mu; Substance P; Synaptic Transmission | 1993 |
Activation of nociceptive reflexes by peripheral kainate receptors.
Topics: Amino Acids; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Morphine; Neurons, Afferent; Nociceptors; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Reflex; Ruthenium Red; Spinal Cord | 1993 |
Blockade of morphine tolerance by ACEA-1328, a novel NMDA receptor/glycine site antagonist.
Topics: Analgesics; Animals; Drug Tolerance; Kinetics; Male; Mice; Morphine; Oocytes; Pain Measurement; Quinoxalines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Xenopus | 1995 |
Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; G(M1) Ganglioside; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Morphine; Pain; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Effect of morphine and abstinence syndrome on [3H]bromoxidine binding to alpha 2-adrenoceptors in rat brain.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Brain; Brimonidine Tartrate; Drug Implants; Hippocampus; Male; Mesencephalon; Morphine; Morphine Dependence; Naloxone; Occipital Lobe; Organ Specificity; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reference Values; Substance Withdrawal Syndrome; Superior Colliculi; Tritium | 1994 |
The anterior pituitary gland as a possible site of action of kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Follicle Stimulating Hormone; Kainic Acid; Luteinizing Hormone; Male; Morphine; Pituitary Gland, Anterior; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Kainic Acid | 1994 |
Inhibition of clonic seizure-like excitatory effects induced by intrathecal morphine using two NMDA receptor antagonists: MK-801 and ACEA-1011.
Topics: Analgesics; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; In Vitro Techniques; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Morphine; Motor Activity; Oocytes; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Seizures; Xenopus laevis | 1994 |
Effects of the AMPA/kainate receptor antagonist DNQX in the nucleus accumbens on drug-induced conditioned place preference.
Topics: Amphetamine; Animals; Choice Behavior; Conditioning, Operant; Male; Morphine; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1993 |
Differential sensitivity of mice bred for stress-induced analgesia to morphine and ACEA-1011 in the formalin test.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Quinoxalines; Stress, Psychological; Swimming | 1996 |
Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test.
Topics: Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Formaldehyde; Gene Expression; Locomotion; Male; Mice; Morphine; Motor Activity; Narcotics; Nociceptors; Oocytes; Quinoxalines; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1996 |
N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4- isoxazoleproprionate (AMPA) glutamate-receptor antagonists have different interactions with the discriminative stimuli of abused drugs.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Conditioning, Operant; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Morphine; Narcotic Antagonists; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1996 |
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch | 1997 |
Efficacy and kinetics of opioid action on acutely dissociated neurons.
Topics: Animals; Brimonidine Tartrate; Calcium Channels; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Locus Coeruleus; Morphine; Narcotics; Potassium Channels; Quinoxalines | 1997 |
The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy.
Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, Spinal; Animals; Behavior, Animal; Brimonidine Tartrate; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hot Temperature; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain Measurement; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance P | 1997 |
Spinal pharmacology of tactile allodynia in diabetic rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Imidazoles; Injections, Spinal; Medetomidine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin | 1997 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Prejunctional control of pH 6-induced bronchoconstriction by NK1, NK2, mu-opioid, alpha2-adrenoceptor and glucocorticoid receptors in guinea-pig isolated perfused lung.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Benzamides; Betamethasone; Biphenyl Compounds; Brimonidine Tartrate; Bronchoconstriction; Calcitonin Gene-Related Peptide; Female; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Male; Morphine; Neurokinin-1 Receptor Antagonists; Perfusion; Piperidines; Quinoxalines; Quinuclidines; Receptors, Adrenergic, alpha-2; Receptors, Cell Surface; Receptors, Glucocorticoid; Receptors, Neurokinin-2; Receptors, Opioid, mu | 1998 |
Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.
Topics: Animals; Central Nervous System Depressants; Diazepam; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; GABA Modulators; Hypnotics and Sedatives; Indoles; Male; Midazolam; Morphine; N-Methylaspartate; Narcotics; Pentobarbital; Phencyclidine; Pregnanolone; Quinoxalines; Rats; Rats, Long-Evans; Serotonin Receptor Agonists; Water | 1997 |
ACEA-1328, an NMDA receptor antagonist, increases the potency of morphine and U50,488H in the tail flick test in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Pain Measurement; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1998 |
ACEA-1328, a NMDA receptor/glycine site antagonist, acutely potentiates antinociception and chronically attenuates tolerance induced by morphine.
Topics: Analgesics, Opioid; Animals; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Pain Measurement; Quinoxalines; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1999 |
Selective modulation of excitatory transmission by mu-opioid receptor activation in rat supraoptic neurons.
Topics: Animals; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Morphine; Narcotics; Neurosecretory Systems; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Supraoptic Nucleus; Synaptic Transmission | 1999 |
Suppression of acute and chronic opioid withdrawal by a selective soluble guanylyl cyclase inhibitor.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acids; Guanylate Cyclase; Locus Coeruleus; Male; Morphine; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2000 |
Interaction between intrathecal morphine and glutamate receptor antagonists in formalin test.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; Morphine; Motor Activity; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Chronic morphine treatment and withdrawal increase extracellular levels of norepinephrine in the rat bed nucleus of the stria terminalis.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Extracellular Space; Glutamic Acid; In Vitro Techniques; Male; Microdialysis; Morphine; Morphine Dependence; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Substance Withdrawal Syndrome | 2000 |
Caroverine inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Conditioning, Classical; Male; Morphine; Naloxone; Narcotic Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2003 |
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Male; Morphine; Narcotics; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
Blockade of ionotropic glutamatergic transmission in the ventral tegmental area attenuates the physical signs of morphine withdrawal in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area; Weight Loss | 2004 |
Ionotropic glutamatergic neurotransmission in the ventral tegmental area modulates DeltaFosB expression in the nucleus accumbens and abstinence syndrome in morphine withdrawal rats.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Nucleus Accumbens; Protein Isoforms; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2005 |
Double dissociation in the neural substrates of acute opiate dependence as measured by withdrawal-potentiated startle.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Fear; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2006 |
Involvement of glutamatergic receptors in the nucleus cuneiformis in modulating morphine-induced antinociception in rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Nociceptors; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 2007 |
Intrathecally injected morphine inhibits inflammatory paw edema: the involvement of nitric oxide and cyclic-guanosine monophosphate.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Neutrophil Infiltration; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Peroxidase; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sildenafil Citrate; Spinal Cord; Sulfones; Time Factors | 2008 |
The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy.
Topics: Animals; Dizocilpine Maleate; Foot; Infusions, Parenteral; Male; Models, Animal; Morphine; Narcotics; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Subarachnoid Space | 2008 |
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dopamine; Drug Interactions; Enzyme Inhibitors; Indomethacin; Interleukin-1beta; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Sensory Receptor Cells; Signal Transduction | 2008 |
Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats.
Topics: Animals; Benzazepines; Conditioning, Classical; Dose-Response Relationship, Drug; Male; Mecamylamine; Morphine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Tobacco Use Disorder; Varenicline | 2010 |
Varenicline and mecamylamine attenuate locomotor sensitization and cross-sensitization induced by nicotine and morphine in mice.
Topics: Analgesics, Opioid; Animals; Benzazepines; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Mice; Morphine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Varenicline | 2010 |
The effects of AMPA receptor blockade in the prelimbic cortex on systemic and ventral tegmental area opiate reward sensitivity.
Topics: Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2013 |
Multiple nicotine training doses in mice as a basis for differentiating the effects of smoking cessation aids.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Morphine; Nicotine; Nicotinic Agonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Smoking Cessation; Tobacco Use Cessation Devices; Varenicline | 2013 |
Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Male; Molsidomine; Morphine; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Photosensitizing Agents; Protoporphyrins; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Restriction Mapping; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase | 2014 |
Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.
Topics: Analgesics; Animals; D-Amino-Acid Oxidase; Drug Discovery; Drug Tolerance; Enzyme Inhibitors; Mice; Morphine; Quinoxalines | 2016 |
Chronic morphine selectively sensitizes the effect of D1 receptor agonist on presynaptic glutamate release in basolateral amygdala neurons that project to prelimbic cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesics, Opioid; Animals; Basolateral Nuclear Complex; Cerebral Cortex; Dopamine Agonists; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Morphine; Neural Pathways; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Receptors, Dopamine D1; Synaptic Potentials; Time Factors | 2018 |
AMPA Receptor in Ventromedial Prefrontal Cortex Plays Different Roles in the Recent and Remote Retrieval of Morphine-Associated Memory.
Topics: Animals; Cell Membrane; Male; Memory; Morphine; Prefrontal Cortex; Quinoxalines; Rats, Sprague-Dawley; Receptors, AMPA | 2019 |
Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death.
Topics: Animals; Cation Transport Proteins; Cyclooxygenase 2; Drug Tolerance; Ferroptosis; Gene Expression Regulation; Hyperalgesia; Inflammation; Iron; Iron Overload; Lipid Peroxidation; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitochondria; Morphine; Neurons; Nociception; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Random Allocation; Reactive Oxygen Species; Receptors, Transferrin; Spinal Cord; Spiro Compounds; Superoxide Dismutase | 2019 |