Page last updated: 2024-08-17

quinoxalines and mequindox

quinoxalines has been researched along with mequindox in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.03)29.6817
2010's31 (93.94)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Dai, MH; Huang, XJ; Ihsan, A; Su, SJ; Wang, X; Wang, YL; Xue, XJ; Yuan, ZH1
Huang, LL; Huang, XJ; Liu, Y; Wang, X; Yan, CX; Yuan, ZH; Zhang, HH; Zhang, LY1
Chen, DM; Huang, LL; Liu, ZY; Yuan, ZH1
Huang, XJ; Ihsan, A; Liu, Q; Su, SJ; Wang, X; Xue, XJ; Yang, CH; Yuan, ZH; Zhou, W1
Huang, LL; Huang, XJ; Ihsan, A; Liu, Q; Liu, ZY; Wang, X; Xue, XJ; Yuan, ZH; Zhang, HF; Zhang, HH; Zhou, W1
Huang, X; Ihsan, A; Li, T; Liu, Y; Liu, Z; Wang, X; Wang, Y; Yang, C; Yu, H; Yuan, Z; Zhang, H1
Chen, H; Qiao, X; Song, J; Xu, Z; Zhang, Y; Zhao, D1
Ding, H; Li, Y; Liu, K; Liu, Y; Si, H; Yang, F; Zeng, D; Zeng, Z1
Huang, C; Lei, H; Nie, X; Tang, H; Wang, Y; Zhao, XJ1
Deng, Y; Huen, MS; Jiang, J; Liu, J; Mu, P; Ouyang, M; Wang, L; Wu, J; Xu, W; Yang, Q; Zhang, C1
Ding, H; He, L; Huang, X; Li, Y; Liu, Y; Shan, Q; Yang, F; Zeng, Z1
Gao, H; Li, S; Li, Y; Peng, B; Zhang, J; Zhou, Z1
Deng, Y; Jiang, J; Mu, P; Tang, X; Wu, J; Zhang, C; Zheng, M1
Ding, H; He, L; Li, G; Li, Y; Liu, Y; Shan, Q; Sun, N; Yang, F; Zeng, Z1
Gu, Q; Lou, X; Song, D; Suo, C; Wang, X; Yin, Y1
Ding, H; Fang, B; He, L; Shen, X; Sun, Y; Tang, Y; Zeng, D; Zeng, Z1
Hao, F; Huang, C; Lei, H; Rantalainen, M; Tang, H; Wang, Y; Zhao, XJ1
Chen, DM; Dai, MH; Huang, LL; Ihsan, A; Liu, ZL; Mannan, S; Peng, DP; Tao, YF; Tu, HG; Wang, X; Wang, YL; Yuan, ZH; Zhang, W1
Liu, ZY; Sun, ZL1
Li, G; Xiao, X; Zhang, Q1
Beier, RC; Cao, X; Li, Y; Liu, K; Shen, J; Zhang, S1
Huang, C; Jiang, L; Lei, H; Tang, H; Wang, Y; Zhao, X1
He, T; Qian, M; Wang, Y; Wu, C1
Cheng, G; Dai, M; Hao, H; Li, B; Liang, G; Liu, Z; Wang, C; Wang, X; Wang, Y; Weng, Z; Yuan, Z; Zhang, H1
Chen, D; Huang, L; Li, J; Liu, Z; Pan, Y; Wan, D; Yin, F; Yuan, Z1
Chen, D; Cheng, G; Dai, M; Guo, P; Ihsan, A; Liu, Z; Luo, X; Wang, X; Yang, C; Yuan, Z1
Chen, Y; Jiang, W; Liu, Y; Wang, Q; Xue, F; Zeng, P1
Li, Y; Song, L; Wu, Y; Xin, M; You, Y1
Chen, D; Huang, L; Liu, Z; Pan, Y; Xie, S; Xu, Y; Yuan, Z; Zhu, X1
Awais, I; Dai, M; Huang, A; Lei, Z; Liu, Q; Wang, X; Wu, Q; Xie, S; Yuan, Z1
Fang, B; Gehring, R; Li, M; Lin, Z; Riviere, JE; Zeng, D; Zeng, Z1
Fatima, Z; Gu, C; Guo, J; Lei, Z; Liu, Q; Maan, MK; Shabbir, MAB; Wang, X; Wu, Q; Xie, S; Yu, H; Yuan, Z; Zhou, K1
An, M; Chen, L; Fu, H; Liang, X; Lin, J; Lin, S; Peng, G; Shu, G; Wei, J; Yin, L; Yuan, Z; Zhang, L; Zhang, W; Zhao, L1

Reviews

1 review(s) available for quinoxalines and mequindox

ArticleYear
The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:8

    Topics: Animals; Carbadox; Humans; Quinoxalines

2013

Trials

1 trial(s) available for quinoxalines and mequindox

ArticleYear
Effects of lactobacillus plantarum ZJ316 on pig growth and pork quality.
    BMC veterinary research, 2012, Jun-25, Volume: 8

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Supplements; Intestine, Small; Lactobacillus plantarum; Meat; Phylogeny; Probiotics; Quinoxalines; Swine

2012

Other Studies

31 other study(ies) available for quinoxalines and mequindox

ArticleYear
Long-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Animals; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Glutathione; Male; Malondialdehyde; Organ Size; Oxidative Stress; Quinoxalines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Superoxide Dismutase; Water-Electrolyte Balance

2009
ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro.
    Chemico-biological interactions, 2010, May-14, Volume: 185, Issue:3

    Topics: Adrenal Cortex; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Mitochondria; Molecular Structure; Oxidation-Reduction; Quinoxalines; Reactive Oxygen Species; Swine; Time Factors

2010
Metabolism of mequindox in liver microsomes of rats, chicken and pigs.
    Rapid communications in mass spectrometry : RCM, 2010, Apr-15, Volume: 24, Issue:7

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Female; Male; Metabolic Networks and Pathways; Microsomes, Liver; Quinoxalines; Rats; Rats, Wistar; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine

2010
Interactions of NADPH oxidase, renin-angiotensin-aldosterone system and reactive oxygen species in mequindox-mediated aldosterone secretion in Wistar rats.
    Toxicology letters, 2010, Oct-05, Volume: 198, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Dose-Response Relationship, Drug; Gene Expression; Glutathione; Kidney; Male; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Quinoxalines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Mineralocorticoid; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase

2010
Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox.
    Toxicology, 2011, Feb-27, Volume: 280, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Janus Kinases; Liver; Male; Oxidative Stress; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Spleen; STAT Transcription Factors

2011
Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats.
    Toxicology and applied pharmacology, 2011, May-01, Volume: 252, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Deoxyguanosine; Glutathione; Male; Malondialdehyde; Organ Size; Oxidative Stress; Phosphoproteins; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Specific Pathogen-Free Organisms; Superoxide Dismutase; Testis

2011
Molecularly imprinted solid-phase extraction combined with high-performance liquid chromatography for analysis of trace olaquindox residues in chick feeds.
    Journal of the science of food and agriculture, 2011, Volume: 91, Issue:13

    Topics: Adsorption; Animal Feed; Animals; Anti-Infective Agents; Chickens; Chromatography, High Pressure Liquid; Food Additives; Gels; Kinetics; Limit of Detection; Microscopy, Electron, Scanning; Molecular Imprinting; Phase Transition; Polymers; Quinoxalines; Reproducibility of Results; Solid Phase Microextraction; Spectroscopy, Fourier Transform Infrared

2011
Pharmacokinetics of mequindox and one of its major metabolites in chickens after intravenous, intramuscular and oral administration.
    Research in veterinary science, 2012, Volume: 93, Issue:1

    Topics: Administration, Oral; Animals; Chickens; Chromatography, High Pressure Liquid; Injections, Intramuscular; Injections, Intravenous; Quinoxalines

2012
Dynamic metabolic response of mice to acute mequindox exposure.
    Journal of proteome research, 2011, Nov-04, Volume: 10, Issue:11

    Topics: Amino Acids; Animals; Anti-Bacterial Agents; Blood Glucose; Citric Acid Cycle; Female; Glycine; Hippurates; Liver; Metabolome; Methylamines; Mice; Principal Component Analysis; Quinoxalines

2011
Mequindox induced cellular DNA damage via generation of reactive oxygen species.
    Mutation research, 2012, Jan-24, Volume: 741, Issue:1-2

    Topics: Animal Husbandry; Anti-Bacterial Agents; Cell Line, Tumor; Cell Survival; DNA Damage; Humans; Mutagens; Quinoxalines; Reactive Oxygen Species

2012
Metabolism of mequindox and its metabolites identification in chickens using LC-LTQ-Orbitrap mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jan-15, Volume: 881-882

    Topics: Animals; Bile; Chickens; Chromatography, Liquid; Feces; Female; Male; Metabolome; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution; Veterinary Drugs

2012
Simultaneous determination of four synthesized metabolites of mequindox in urine samples using ultrasound-assisted dispersive liquid-liquid microextraction combined with high-performance liquid chromatography.
    Talanta, 2012, Jan-15, Volume: 88

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Emulsions; Ethane; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Methanol; Oxidation-Reduction; Quinoxalines; Reproducibility of Results; Solvents; Sonication; Swine

2012
Carbonyl reduction of mequindox by chicken and porcine cytosol and cloned carbonyl reductase 1.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4

    Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Biotransformation; Cell Survival; Chickens; Chromatography, High Pressure Liquid; Cloning, Molecular; Cytosol; Escherichia coli; Hep G2 Cells; Humans; Liver; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Quinoxalines; Sequence Alignment; Species Specificity; Sus scrofa

2012
Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration.
    Research in veterinary science, 2012, Volume: 93, Issue:3

    Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Half-Life; Injections, Intravenous; Molecular Structure; Quinoxalines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry

2012
Liquid chromatography tandem mass spectrometry for the simultaneous determination of mequindox and its metabolites in porcine tissues.
    Journal of separation science, 2012, Volume: 35, Issue:10-11

    Topics: Animals; Chromatography, High Pressure Liquid; Kidney; Liver; Muscles; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Swine; Swine Diseases; Tandem Mass Spectrometry; Veterinary Drugs

2012
Systems responses of rats to mequindox revealed by metabolic and transcriptomic profiling.
    Journal of proteome research, 2012, Sep-07, Volume: 11, Issue:9

    Topics: Animals; Female; Gene Expression Profiling; Histocytochemistry; Least-Squares Analysis; Liver; Metabolic Networks and Pathways; Metabolome; Metabolomics; Nuclear Magnetic Resonance, Biomolecular; Organic Chemicals; Principal Component Analysis; Quinoxalines; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Transcriptome; Urine

2012
Genotoxicity evaluation of Mequindox in different short-term tests.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 51

    Topics: Animals; Bone Marrow Cells; Carbadox; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Quinoxalines; Salmonella typhimurium

2013
Porous molecularly imprinted monolithic capillary column for on-line extraction coupled to high-performance liquid chromatography for trace analysis of antimicrobials in food samples.
    Talanta, 2014, Volume: 123

    Topics: Animals; Anti-Infective Agents; Chickens; Chromatography, High Pressure Liquid; Eggs; Food Analysis; Meat; Methacrylates; Microscopy, Electron, Scanning; Molecular Imprinting; Molecular Structure; Porosity; Quinoxalines; Reproducibility of Results; Silicon Dioxide; Solid Phase Extraction; Solvents; Spectrophotometry, Infrared; Sulfameter; Sulfaquinoxaline; Swine; Thermogravimetry

2014
Simultaneous determination of mequindox, quinocetone, and their major metabolites in chicken and pork by UPLC-MS/MS.
    Food chemistry, 2014, Oct-01, Volume: 160

    Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Food Contamination; Meat; Quinoxalines; Solid Phase Extraction; Swine; Tandem Mass Spectrometry; Veterinary Drugs

2014
Dynamic changes in metabolic profiles of rats subchronically exposed to mequindox.
    Molecular bioSystems, 2014, Volume: 10, Issue:11

    Topics: Animals; Biomarkers; Body Weight; Citric Acid Cycle; Female; Gluconeogenesis; Glycolysis; Lipid Metabolism; Liver; Metabolome; Metabolomics; Quinoxalines; Rats; Rats, Wistar

2014
Mequindox resistance and in vitro efficacy in animal-derived Escherichia coli strains.
    Veterinary microbiology, 2015, Jun-12, Volume: 177, Issue:3-4

    Topics: Animals; Anti-Bacterial Agents; Chickens; China; Ducks; Escherichia coli; Escherichia coli Infections; Geese; Genotype; Microbial Sensitivity Tests; Operon; Polymerase Chain Reaction; Poultry Diseases; Quinoxalines; Swine; Swine Diseases

2015
Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Anti-Bacterial Agents; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Annotation; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Proteomics; Quinoxalines; Reactive Oxygen Species; SOS Response, Genetics; Structure-Activity Relationship; Tirapazamine; Triazines

2015
Metabolism, Distribution, and Elimination of Mequindox in Pigs, Chickens, and Rats.
    Journal of agricultural and food chemistry, 2015, Nov-11, Volume: 63, Issue:44

    Topics: Animals; Anti-Bacterial Agents; Chickens; Kidney; Liver; Molecular Structure; Quinoxalines; Rats; Swine; Tissue Distribution

2015
High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.
    Toxicology, 2016, Feb-03, Volume: 341-343

    Topics: Adrenal Gland Diseases; Aldosterone; Antioxidants; Biotransformation; Cell Line; Cell Survival; Cytochrome P-450 CYP11B2; Humans; Oxidative Stress; Proanthocyanidins; Quinoxalines; RNA, Messenger; Steroid 11-beta-Hydroxylase

2016
Cytotoxicity of mequindox and its metabolites in HepG2 cells in vitro and murine hepatocytes in vivo.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2016, Volume: 797

    Topics: Animals; Cell Cycle; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Mice; Quinoxalines

2016
Simple and Fast Extraction-Coupled UPLC-MS/MS Method for the Determination of Mequindox and Its Major Metabolites in Food Animal Tissues.
    Journal of agricultural and food chemistry, 2016, Mar-23, Volume: 64, Issue:11

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Food Contamination; Limit of Detection; Liver; Meat; Muscles; Quinoxalines; Reproducibility of Results; Swine; Tandem Mass Spectrometry

2016
Physiologically based pharmacokinetic model for quinocetone in pigs and extrapolation to mequindox.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2017, Volume: 34, Issue:2

    Topics: Animals; Drug Residues; Models, Biological; Molecular Dynamics Simulation; Monte Carlo Method; Quinoxalines; Swine

2017
Toxic metabolites, MAPK and Nrf2/Keap1 signaling pathways involved in oxidative toxicity in mice liver after chronic exposure to Mequindox.
    Scientific reports, 2017, 02-03, Volume: 7

    Topics: Animals; Anti-Infective Agents; Female; Kelch-Like ECH-Associated Protein 1; Liver; Male; MAP Kinase Signaling System; Mice; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Quinoxalines

2017
Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling.
    Journal of agricultural and food chemistry, 2017, Jul-19, Volume: 65, Issue:28

    Topics: Animals; Anti-Bacterial Agents; Drug Residues; Injections, Intramuscular; Liver; Quinoxalines; Swine; Tissue Distribution; Veterinary Drugs

2017
Mequindox induces apoptosis, DNA damage, and carcinogenicity in Wistar rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 127

    Topics: Animals; Apoptosis; Body Weight; Carcinogens; Dietary Exposure; DNA Damage; Female; Histones; Immunohistochemistry; Liver; Male; Neoplasms, Experimental; NF-kappa B; Organ Size; Phosphoproteins; Quinoxalines; Rats, Wistar; Survival Analysis

2019
Casein nanoparticles as oral delivery carriers of mequindox for the improved bioavailability.
    Colloids and surfaces. B, Biointerfaces, 2020, Volume: 195

    Topics: Administration, Oral; Animals; Biological Availability; Caseins; Drug Carriers; Nanoparticles; Quinoxalines

2020