quinoxalines has been researched along with liproxstatin-1 in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (40.00) | 24.3611 |
| 2020's | 18 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aichler, M; Basavarajappa, D; Beck, H; Bornkamm, GW; Conrad, M; Eggenhofer, E; Esposito, I; Förster, H; Friedmann Angeli, JP; Geissler, EK; Hammond, VJ; Heinrichmeyer, M; Herbach, N; Kagan, VE; Kobayashi, S; Neff, F; O'Donnell, VB; Proneth, B; Rådmark, O; Schick, JA; Schneider, M; Seibt, T; Stockwell, BR; Thomas, SB; Tyurin, VA; Tyurina, YY; Walch, A; Wanke, R; Yefremova, O | 1 |
| Dong, T; Lei, X; Liao, D; Liu, X | 1 |
| Degterev, A; Linkermann, A | 1 |
| Cao, JY; Dixon, SJ | 1 |
| Bradbury, MS; Chen, F; Conrad, M; Gao, M; Gonen, M; Ingold, I; Jiang, X; Kim, SE; Ma, K; Monette, S; Overholtzer, M; Pauliah, M; Quinn, T; Riegman, M; Turker, MZ; Wiesner, U; Zanzonico, P; Zhang, L | 1 |
| Conrad, M; Doll, S | 1 |
| Chen, D; Liu, J; Shan, C; Sheng, X; Sun, B; Yang, J | 1 |
| Kasukabe, T; Kumakura, S; Yamaguchi, Y | 1 |
| Acharya, A; Chaudhari, U; Hengstler, JG; Hescheler, J; Nemade, H; Papadopoulos, S; Sachinidis, A | 1 |
| Feng, D; Li, Y; Liu, D; Ning, S; Sun, R; Tian, D; Tian, X; Wang, Z; Yao, J; Zhang, F; Zhao, Y | 1 |
| Bopassa, JC; Feng, Y; Imam Aliagan, AD; Madungwe, NB; Tombo, N | 1 |
| Chen, X; Feng, M; Liu, T; Wan, L; Yao, W; Zhang, B; Zhang, C; Zhang, Y | 1 |
| Baatarjav, C; Higashi, T; Kamata, R; Karasawa, T; Komada, T; Ohno, N; Sampilvanjil, A; Takahashi, M; Watanabe, S; Yamada, N | 1 |
| Jiang, P; Jiang, Y; Li, C; Ma, D; Wang, J; Zhang, D | 1 |
| Capelletti, MM; Manceau, H; Peoc'h, K; Puy, H | 1 |
| Cho, SS; Ki, SH; Kim, KM | 1 |
| Bai, L; Dai, E; Han, L; Kang, R; Liu, J; Tang, D; Xie, Y; Zeh, HJ | 1 |
| Han, J; He, Y; Hu, B; Li, W; Nie, G; Tang, D; Zhao, L; Zheng, Z | 1 |
| Cao, Y; Fu, XJ; He, C; Li, JR; Li, Y; Lu, XY; Peng, YC; Tong, Y; Wang, L; Wei, YY; Xu, HZ; Yan, F; Yao, Y; Zhou, H; Zhou, YF; Zhuang, JF | 1 |
| An, H; Bao, Y; Huang, D; Shen, N; Wang, K; Yang, J; Yu, F; Zeng, X; Zheng, L; Zhou, W | 1 |
| Fan, G; Li, K; Liu, J; Sun, T; Tao, N | 1 |
| Du, J; Huang, X; Lan, W; Lin, W; Long, Z; Ma, W; Wang, L; Yang, Y; Zhang, N; Zheng, B; Zhong, F | 1 |
| Dai, X; Liu, N; Lu, W; Ma, Q; Qu, X; Zhu, C | 1 |
| Borrillo, L; Brown, ED; Côté, JP; French, S; Gaulin, JL; Guo, ABY; Hubbard, B; Hung, DT; Johnson, JW; Klobucar, K; Lee, KK; Magolan, J; Serrano-Wu, MH | 1 |
| Chen, X; Chen, Z; Dai, G; Gan, Y; He, Y; Li, B; Ru, F; Xia, W; Zhang, B | 1 |
| Xia, H; You, F; Zhang, Z | 1 |
| Chen, X; Fu, Q; Hu, S; Shi, Z; Wang, A; Wang, L; Wang, T; Wang, Y; Xu, W; Zhang, S | 1 |
| Bao, C; Hu, J; Hua, L; Li, Z; Liu, C; Liu, Q; Xu, S | 1 |
| Cheng, P; Dai, Y; Deng, DH; Dong, HQ; Liang, SJ; Sun, N; Xu, YL | 1 |
| Ge, A; Ge, J; Wang, S; Xu, H; Yang, K; Yuan, X; Zeng, J; Zeng, L | 1 |
7 review(s) available for quinoxalines and liproxstatin-1
| Article | Year |
|---|---|
Using Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis.
Topics: Animals; Cell Death; Humans; Mitochondria; Necrosis; Pyroptosis; Quinoxalines; Signal Transduction; Small Molecule Libraries; Spiro Compounds | 2015 |
Generation of small molecules to interfere with regulated necrosis.
Topics: Animals; Apoptosis; Cyclohexylamines; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Mice; Necrosis; Organic Chemicals; Phenylenediamines; Protein Kinases; Pyridazines; Quinoxalines; Receptor-Interacting Protein Serine-Threonine Kinases; Spiro Compounds; Sulfones | 2016 |
Mechanisms of ferroptosis.
Topics: Cell Death; Cell Membrane; Cyclohexylamines; Fatty Acids, Unsaturated; Glutathione; Glutathione Peroxidase; Iron; Neoplasms; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Reactive Oxygen Species; Spiro Compounds | 2016 |
Iron and ferroptosis: A still ill-defined liaison.
Topics: Animals; Antioxidants; Cell Death; Cyclohexylamines; Glutathione Peroxidase; Humans; Iron; Iron Chelating Agents; Iron Metabolism Disorders; Lipid Peroxidation; Necrosis; Neuroaxonal Dystrophies; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Renal Insufficiency; Reperfusion Injury; Spiro Compounds | 2017 |
Ferroptosis in Liver Diseases: An Overview.
Topics: alpha-Tocopherol; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Cyclohexylamines; Cysteine; Ferroptosis; Glutathione; Heme; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Lipoxygenase; Liver Diseases; Liver Neoplasms; Oxidative Stress; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Sorafenib; Spiro Compounds; Sulfasalazine; Tumor Suppressor Protein p53 | 2020 |
Emerging roles of ferroptosis in liver pathophysiology.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexylamines; Deferoxamine; Disease Models, Animal; Disease Progression; Fatty Acids, Unsaturated; Ferroptosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Spiro Compounds | 2020 |
The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components.
Topics: Cyclohexylamines; Ferroptosis; Glutathione; Humans; Iron; Ischemic Stroke; Lipid Peroxidation; Oxidative Stress; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Spiro Compounds | 2022 |
23 other study(ies) available for quinoxalines and liproxstatin-1
| Article | Year |
|---|---|
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Topics: Acute Kidney Injury; Animals; Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Cardiolipins; Cell Line; Glutathione Peroxidase; Humans; Imidazoles; In Situ Nick-End Labeling; Indoles; Kidney; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Peroxidases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Reperfusion Injury; Spiro Compounds | 2014 |
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth.
Topics: alpha-MSH; Amino Acids; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Humans; Iron; Lysosomes; Melanoma; Mice; Mice, SCID; Nanoparticles; Particle Size; Polyethylene Glycols; Quinoxalines; Silicon Dioxide; Spiro Compounds; Xenograft Model Antitumor Assays | 2016 |
Theoretical insights into the mechanism of ferroptosis suppression via inactivation of a lipid peroxide radical by liproxstatin-1.
Topics: Free Radicals; Iron; Kinetics; Lipid Peroxides; Molecular Dynamics Simulation; Phosphatidylcholines; Quantum Theory; Quinoxalines; Spiro Compounds; Structure-Activity Relationship; Thermodynamics; Ubiquinone | 2017 |
Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Dioxolanes; Diterpenes; Drug Synergism; Fibroblasts; Humans; Iron; Mice; Pancreatic Neoplasms; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Spiro Compounds; Sulfasalazine | 2018 |
Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells.
Topics: Anthracyclines; Antineoplastic Agents; Apoptosis; Benzothiazoles; Calcium Channels; Calcium-Binding Proteins; Cell Death; Cells, Cultured; Cytoskeletal Proteins; Down-Regulation; Etoposide; Gene Expression; Humans; MicroRNAs; Mitochondria, Heart; Muscle Contraction; Myocytes, Cardiac; Pluripotent Stem Cells; Quinoxalines; Spiro Compounds; Toluene; Up-Regulation | 2018 |
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Coenzyme A Ligases; DNA-Binding Proteins; Ferroptosis; Humans; Intestines; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Models, Animal; Promoter Regions, Genetic; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Rosiglitazone; Sp1 Transcription Factor; Spiro Compounds | 2019 |
Liproxstatin-1 protects the mouse myocardium against ischemia/reperfusion injury by decreasing VDAC1 levels and restoring GPX4 levels.
Topics: Animals; Antioxidants; Calcium; Cardiotonic Agents; Ferroptosis; Heart; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Reactive Oxygen Species; Spiro Compounds; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channel 2; Voltage-Dependent Anion Channels | 2019 |
Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death.
Topics: Animals; Cation Transport Proteins; Cyclooxygenase 2; Drug Tolerance; Ferroptosis; Gene Expression Regulation; Hyperalgesia; Inflammation; Iron; Iron Overload; Lipid Peroxidation; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitochondria; Morphine; Neurons; Nociception; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Random Allocation; Reactive Oxygen Species; Receptors, Transferrin; Spinal Cord; Spiro Compounds; Superoxide Dismutase | 2019 |
Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells.
Topics: Animals; Cell Death; Cell Line; Cyclohexylamines; Deferoxamine; Endothelial Cells; Ferroptosis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Phenylenediamines; Quinoxalines; Rats; Rats, Sprague-Dawley; Siderophores; Smoke; Spiro Compounds; Tissue Inhibitor of Metalloproteinase-1 | 2020 |
Inhibition of Ferroptosis Attenuates Acute Kidney Injury in Rats with Severe Acute Pancreatitis.
Topics: Acute Kidney Injury; Animals; Ferroptosis; Male; Pancreatitis; Quinoxalines; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Spiro Compounds; Taurocholic Acid | 2021 |
Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway.
Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Pancreatic Ductal; Cell Death; Cell Transformation, Neoplastic; Diet; Disease Models, Animal; DNA; Female; Ferroptosis; Humans; Iron; Macrophages; Male; Membrane Proteins; Mice; Mice, Knockout; Pancreas; Pancreatitis; Phospholipid Hydroperoxide Glutathione Peroxidase; Proto-Oncogene Proteins p21(ras); Quinoxalines; Spiro Compounds; Tumor Microenvironment | 2020 |
Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity.
Topics: Animals; Cell Line; Hair Cells, Auditory; Mice; Neomycin; Ototoxicity; Quinoxalines; Reactive Oxygen Species; Spiro Compounds | 2020 |
Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage.
Topics: Animals; Ferroptosis; Quinoxalines; Rats; Rats, Sprague-Dawley; Spiro Compounds; Subarachnoid Hemorrhage | 2021 |
Benefits of Iron Chelators in the Treatment of Parkinson's Disease.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Deferoxamine; Dopaminergic Neurons; Ferric Compounds; Ferroptosis; Humans; Iron Chelating Agents; Iron Overload; Nerve Growth Factor; Neuroprotective Agents; Parkinson Disease, Secondary; Quaternary Ammonium Compounds; Quinoxalines; Rats; Reactive Oxygen Species; Spiro Compounds | 2021 |
Liproxstatin-1 alleviates bleomycin-induced alveolar epithelial cells injury and mice pulmonary fibrosis via attenuating inflammation, reshaping redox equilibrium, and suppressing ROS/p53/α-SMA pathway.
Topics: A549 Cells; Actins; Alveolar Epithelial Cells; Animals; Bleomycin; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Quinoxalines; Reactive Oxygen Species; Spiro Compounds; Tumor Suppressor Protein p53 | 2021 |
Shuganning injection, a traditional Chinese patent medicine, induces ferroptosis and suppresses tumor growth in triple-negative breast cancer cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; China; Cyclohexylamines; Drugs, Chinese Herbal; Female; Ferroptosis; Heme Oxygenase-1; Humans; Iron; Lipid Peroxidation; Medicine, Chinese Traditional; Mice; Mice, Nude; Phenylenediamines; Quinoxalines; Spiro Compounds; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2021 |
Silencing long non-coding RNA MEG8 inhibits the proliferation and induces the ferroptosis of hemangioma endothelial cells by regulating miR-497-5p/NOTCH2 axis.
Topics: Amino Acid Transport System y+; Apoptosis Regulatory Proteins; Base Sequence; Cell Proliferation; Cyclohexylamines; Down-Regulation; Endothelial Cells; Ferroptosis; Gene Silencing; Hemangioma; Humans; MicroRNAs; Mitochondrial Proteins; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Receptor, Notch2; RNA, Long Noncoding; RNA, Small Interfering; Spiro Compounds | 2021 |
Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Cell Membrane Permeability; Cell Wall; Drug Synergism; Enzyme Inhibitors; Escherichia coli; High-Throughput Screening Assays; Klebsiella pneumoniae; Lipopolysaccharides; Polymyxins; Pseudomonas aeruginosa; Quinoxalines; Spiro Compounds; Vancomycin | 2021 |
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis.
Topics: Animals; Carbolines; Cell Death; Cell Line; Cell Proliferation; Cell Shape; Collagen; Disease Models, Animal; Epithelial Cells; Ferroptosis; Fibrosis; Humans; Iron; Kidney Tubules; Lipid Peroxidation; Male; Mice, Inbred C57BL; Myofibroblasts; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Spiro Compounds; Ureteral Obstruction | 2021 |
Inhibiting ACSL1-Related Ferroptosis Restrains Murine Coronavirus Infection.
Topics: Animals; Coenzyme A Ligases; Coronavirus Infections; Cytokines; Disease Models, Animal; Ferroptosis; Genes, Viral; Lung Injury; Macrophages; Mice; Mice, Inbred C57BL; Murine hepatitis virus; Quinoxalines; RAW 264.7 Cells; Spiro Compounds; Toll-Like Receptor 4; Virus Replication | 2021 |
Ferroptosis plays an important role in promoting ionizing radiation-induced intestinal injuries.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Ferroptosis; Gene Expression; Glutathione; Intestine, Small; Intestines; Male; Malondialdehyde; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Mitochondria; Quinoxalines; Radiation Injuries, Experimental; Radiation, Ionizing; Reverse Transcriptase Polymerase Chain Reaction; Spiro Compounds; Superoxide Dismutase | 2022 |
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
Topics: Animals; Asthma; Epithelial Cells; Ferroptosis; Inflammation; Interleukin-13; Lipopolysaccharides; Mice; Ovalbumin; Quinoxalines; Spiro Compounds | 2022 |
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells.
Topics: Apoptosis; Caspase 3; Cell Cycle; Cell Cycle Checkpoints; Cell Proliferation; Humans; K562 Cells; Leukemia; Pore Forming Cytotoxic Proteins; Pyroptosis; Quinoxalines; Spiro Compounds | 2022 |