quinoxalines has been researched along with kynurenic acid in 132 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (8.33) | 18.7374 |
| 1990's | 98 (74.24) | 18.2507 |
| 2000's | 18 (13.64) | 29.6817 |
| 2010's | 5 (3.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Copenhagen, DR; Dixon, DB | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Bowyer, JF; Frame, LT; Lipe, GW; Newport, GD | 1 |
| Arellano, RO; Conde-Guerri, B; Matute, C; Miledi, R | 1 |
| DiMicco, JA; Soltis, RP | 2 |
| Bear, MF; Connors, BW; Press, WA | 1 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Pinnock, RD | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Brown, T; Dingledine, R; Eaton, JV; McBain, CJ | 1 |
| Deschênes, M; Pinault, D | 1 |
| Lodge, D; Millar, JD; Pralong, E | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Mody, I; Staley, KJ | 1 |
| Colquhoun, D; Edwards, FA; Gibb, AJ | 1 |
| DeFeo, PA; Hargrove, H; Patel, J; Salama, AI; Thompson, C; Zinkand, WC | 1 |
| Kim, HG; Miller, RF | 1 |
| Armstrong, DM; Costa, E; Mereu, G; Vicini, S | 1 |
| Dudek, FE; Wuarin, JP | 1 |
| Davidoff, RA; Hackman, JC | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Larson-Prior, LJ; Slater, NT; Ulinski, PS | 1 |
| Collins, GG | 1 |
| Choi, DW; Goldberg, MP; Kaku, DA | 1 |
| Hicks, TP; Kaneko, T; Metherate, R; Oka, JI; Stark, CA | 1 |
| Andrew, M; Farley, JM; Ho, IK; Oden, G; Rockhold, RW | 1 |
| Abrahams, TP; Gillis, RA; Hornby, PJ; Taveira DaSilva, AM; Walton, DP | 1 |
| Cerne, R; Gerber, G; Randić, M | 1 |
| Bruce, EN; Jung, R; Katona, PG | 1 |
| Christenson, J; Grillner, S | 1 |
| Eshhar, N; Ortega, A; Teichberg, VI | 1 |
| Ikonomidou, C; Sieklucka, M; Turski, WA; Urbańska, E | 1 |
| Paschetto, KA; Pullan, LM; Verticelli, AM | 1 |
| Larson-Prior, LJ; McCrimmon, DR; Slater, NT | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Miyamoto, T; Okada, Y; Sakurai, T | 1 |
| Feldman, JL; Liu, G; Smith, JC | 1 |
| Boeijinga, PH; Lopes da Silva, FH; Pennartz, CM | 1 |
| Doi, K; Matsunaga, T; Tsumoto, T | 1 |
| Dingledine, R; Kleckner, NW; McBain, CJ | 1 |
| Alesiani, M; Cherici, G; Galli, A; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Dunlop, J; Grieve, A; Griffiths, R; Schousboe, A | 1 |
| Dingledine, R; Kleckner, NW | 1 |
| Harris, KM; Miller, RJ | 1 |
| Garthwaite, G; Garthwaite, J | 1 |
| Evans, RH; Long, SK | 1 |
| Gerber, G; Randić, M | 1 |
| Aizenman, E; Karschin, A; Lipton, SA | 1 |
| Morris, R | 1 |
| Wu, SM; Yang, XL | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 1 |
| Song, XJ; Zhao, ZQ | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E | 2 |
| Dowling, JE; Grant, GB | 1 |
| Hatton, GI; Smithson, KG; Yang, QZ | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Guastella, J; Huettner, JE; Keana, JF; Weber, E; Woodward, RM | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Croucher, MJ; Patel, DR; Sturt, NJ | 1 |
| Barth, A; Malouf, AT; Newell, DW | 1 |
| Guyenet, PG; Li, YW | 1 |
| Brady, RJ; Smith, KL; Swann, JW | 1 |
| Sugiyama, M; Takahashi, MP; Tsumoto, T | 1 |
| Witkin, JM | 1 |
| Haddad, GG; Jiang, C | 1 |
| Cauller, LJ; Connors, BW | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, P; Xu, Y; Yang, GY | 1 |
| Hagevik, A; McClellan, AD | 1 |
| Krnjević, K; Zhu, PJ | 1 |
| Abrahams, TP; Chen, K; Dasilva, AM; Gillis, RA; Hornby, PJ | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, PR; Xu, Y | 1 |
| Abercrombie, ED; Keefe, KA; Zigmond, MJ | 1 |
| Abe, K; Saito, H | 1 |
| Féger, J; Mouroux, M | 1 |
| Gdovin, M; Li, A; Nattie, EE | 1 |
| Buchwald, NA; Cohen, RW; Levine, MS; Radisavljevic, Z; Siviy, SM; Walsh, JP | 1 |
| Guo, JZ; Ichinose, T; Murakoshi, T | 1 |
| Birrell, GJ; Marcoux, FW | 1 |
| Cappendijk, SL; de Vries, R; Dzoljic, MR | 1 |
| Heary, RF; Krieger, AJ; Maniker, AH; Sapru, HN | 1 |
| Laufer, M; Negishi, K; Salas, R | 1 |
| Ennis, M; Shipley, MT; Zimmer, LA | 1 |
| Chen, K; Godfrey, DA; Waller, HJ | 1 |
| Erdõ, SL; Molnár, P | 1 |
| Bonham, AC; Wilson, CG; Zhang, Z | 1 |
| Cai, SX; Espitia, SA; Hawkinson, JE; Ilyin, V; Keana, JF; Kher, SM; Tran, M; Weber, E; Woodward, RM; Zhou, ZL | 1 |
| Diamond, JS; Jahr, CE | 1 |
| Bettelini, L; Corsi, M; Fina, P; Trist, DG | 1 |
| Faussone-Pellegrini, MS; Lombardi, G; Matini, P; Moroni, F | 1 |
| Cook, JC; Gregg, AE; Sanders, BJ; Soltis, RP | 1 |
| Brodfuehrer, PD; Thorogood, MS | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Osawa, M | 1 |
| Beitz, AJ; Clark, HB; Feddersen, RM; Iadecola, C; Yang, G; Zhang, F | 1 |
| Maruoka, Y; Nakamura, M; Ohno, Y; Otani, K; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Cook, JC; Flickinger, KA; Gregg, AE; Soltis, RP; Stratton, JM | 1 |
| Roberts, A; Wolf, E; Zhao, FY | 1 |
| Roberts, A; Zhao, FY | 1 |
| Bonagamba, LG; Haibara, AS; Machado, BH | 1 |
| Curry, K; Pajouhesh, H | 1 |
| Arvigo, D; Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Dong, LP; Wang, TY | 1 |
| Cano, J; Machado, A; Merino, M; Vizuete, ML | 1 |
| Ichinohe, N; Kitai, ST; Rohrbacher, J | 1 |
| Croucher, MJ; Patel, DR; Young, AM | 1 |
| Feroah, TR; Forster, HV; Geiger, L; Hodges, M; Martino, P; Pan, LG; Serra, A; Wenninger, JM | 1 |
| Barnabi, F; Cechetto, DF | 1 |
| Jahr, CE; Wadiche, JI | 1 |
| Feroah, TR; Forster, HV; Fuentes, CG; Hodges, M; Martino, P; Pan, L; Rice, T; Wenninger, J | 1 |
| Bruno, JP; Kravitz, BA; Neigh-McCandless, G; Sarter, M | 1 |
| Cai, SX; Espitia, SA; Hawkinson, JE; Keana, JF; Kher, SM; Tran, M; Weber, E; Whittemore, ER; Woodward, RM; Zhou, ZL | 1 |
| Chen, QH; Haywood, JR; Toney, GM | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Pittaluga, A; Pugliese, AM; Romanelli, MN | 1 |
| Liu, X; Stan Leung, L | 1 |
| Deuchars, J; Deuchars, SA; Milligan, CJ; Stornetta, RL | 1 |
| Katayama, S; Nagata, R; Ohtani, K; Shimago, K; Tanaka, H | 1 |
| Allen, CN; Brown, RL; Perez-Leon, JA; Robinson, DW; Warren, EJ | 1 |
| Sartor, DM; Verberne, AJ | 1 |
| Solomon, IC; Warren, KA | 1 |
| Fukushima, M; Kano, T; Katayama, Y; Koshinaga, M; Suma, T | 1 |
| Eguchi, K; Kanda, T; Takahashi, T; Yamashita, T | 1 |
| Hirose, Y; Minami, A; Nakamura, T; Oguri, H; Oikawa, H; Watanabe, K | 1 |
| Overstreet-Wadiche, L; Rudolph, S; Wadiche, JI | 1 |
| Brown, AM; Chen, S; Evans, RD; Hamner, MA; Ransom, BR; Yang, X; Ye, ZC | 1 |
| Dubach, MF; Dybdal, D; Forcelli, PA; Gale, K; Malkova, L; Wellman, LL | 1 |
| Babic, S; Hachimine, P; Ranaldi, R; Seepersad, N | 1 |
2 review(s) available for quinoxalines and kynurenic acid
| Article | Year |
|---|---|
The glycine coagonist site of the NMDA receptor.
Topics: Animals; Binding Sites; Brain; Glycine; Kainic Acid; Kynurenic Acid; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 1990 |
Tricyclic quinoxalinediones, aza-kynurenic acids, and indole-2-carboxylic acids as in vivo active NMDA-glycine antagonists.
Topics: Carboxylic Acids; Indoles; Kynurenic Acid; Models, Molecular; Quinoxalines; Receptors, Glycine; Structure-Activity Relationship | 2006 |
130 other study(ies) available for quinoxalines and kynurenic acid
| Article | Year |
|---|---|
Suppression of a calcium current by CNQX and kynurenate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ictaluridae; Kynurenic Acid; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
A further evaluation of the effects of K+ depolarization on glutamate-evoked [3H]dopamine release from striatal slices.
Topics: Animals; Corpus Striatum; Culture Techniques; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Kynurenic Acid; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
mRNA coding for neurotransmitter receptors in a human astrocytoma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Animals; Astrocytoma; Brain Neoplasms; Calcium Channels; Cell Line; Culture Techniques; Female; Glutamates; Humans; Kainic Acid; Kynurenic Acid; Male; Membrane Potentials; Oocytes; Pirenzepine; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1992 |
Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Rate; Hypothalamus, Middle; Kynurenic Acid; Male; Microinjections; Motor Activity; Neurotoxins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stress, Physiological | 1992 |
Long-term potentiation in slices of kitten visual cortex and the effects of NMDA receptor blockade.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Cats; Electric Stimulation; Evoked Potentials; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Visual Cortex | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
CNQX increases spontaneous inhibitory input to CA3 pyramidal neurones in neonatal rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electric Conductivity; Hippocampus; In Vitro Techniques; Interneurons; Kynurenic Acid; Neural Inhibition; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley | 1992 |
Control of 40-Hz firing of reticular thalamic cells by neurotransmitters.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Electric Conductivity; Female; gamma-Aminobutyric Acid; Ketanserin; Kynurenic Acid; Male; Neurons; Neurotransmitter Agents; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reticular Formation; Scopolamine; Thalamic Nuclei | 1992 |
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Chlorides; Electrodes; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Ion Channels; Kynurenic Acid; Male; Membrane Potentials; Neural Conduction; Neuromuscular Junction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1992 |
ATP receptor-mediated synaptic currents in the central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine Triphosphate; Animals; Bicuculline; Brain; Chlorocebus aethiops; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Ganglionic Blockers; Glutamates; Glutamic Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Ion Channels; Kynurenic Acid; Mecamylamine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Suramin; Tetrodotoxin | 1992 |
Quisqualate neurotoxicity in rat cortical cultures: pharmacology and mechanisms.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Rods and cones activate different excitatory amino acid receptors on the mudpuppy retinal horizontal cell.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Necturus; Photic Stimulation; Photoreceptor Cells; Quinoxalines; Receptors, Neurotransmitter; Retina; Synaptic Transmission | 1991 |
Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dopamine; Evoked Potentials; Glutamates; In Vitro Techniques; Kynurenic Acid; Mecamylamine; Mesencephalon; Neurons; Picrotoxin; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Excitatory amino acid antagonists inhibit synaptic responses in the guinea pig hypothalamic paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Quinoxalines; Synapses | 1991 |
Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kynurenic Acid; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Potassium Channels; Quinoxalines; Rana pipiens; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synaptic Transmission | 1991 |
Interaction of hypothalamic GABAA and excitatory amino acid receptors controlling heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cerebellum; Chlorides; Cyclic GMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Lithium; Lithium Chloride; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nipecotic Acids; Nitroprusside; Organic Anion Transporters; Proline; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Secretory Rate; Sodium; Stimulation, Chemical | 1991 |
Excitatory amino acid receptor-mediated transmission in geniculocortical and intracortical pathways within visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Cortex; Electric Stimulation; Geniculate Bodies; Kynurenic Acid; Neural Pathways; Neurons; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission; Turtles; Visual Cortex | 1991 |
Pharmacological evidence that NMDA receptors contribute to mono- and di-synaptic potentials in slices of mouse olfactory cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Mice; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synapses | 1991 |
Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Culture Media; Dizocilpine Maleate; Fetus; Glucose; Kynurenic Acid; Mice; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Amino acids as transmitters of synaptic excitation in neocortical sensory processes.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Calcium; Cats; Cerebral Cortex; Chromatography, High Pressure Liquid; Electric Stimulation; Electrodes; Female; Iontophoresis; Kynurenic Acid; Magnesium; Male; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Quinoxalines; Somatosensory Cortex; Synapses; Thalamus | 1991 |
Glutamate receptor antagonists block cocaine-induced convulsions and death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Time Factors | 1991 |
An excitatory amino acid(s) in the ventrolateral medulla is (are) required for breathing to occur in the anesthetized cat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Female; Glycine; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Respiration | 1991 |
Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in rat spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Cardiorespiratory responses to glutamatergic antagonists in the caudal ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Hemodynamics; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Pressoreceptors; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Respiration | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Properties of kainate receptor/channels on cultured Bergmann glia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antibodies, Monoclonal; Calcium; Cell Membrane; Cells, Cultured; Cerebellar Cortex; Chick Embryo; Chlorides; Dipeptides; Ion Channels; Kainic Acid; Kinetics; Kynurenic Acid; Models, Neurological; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Kainic Acid; Receptors, Neurotransmitter; Rubidium; Sodium | 1991 |
Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Female; Glutamate Decarboxylase; Kynurenic Acid; Male; Microinjections; Microscopy, Electron; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one (HA-966).
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Glycine; Kynurenic Acid; Male; Pyrrolidinones; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermine; Stereoisomerism; Synaptosomes | 1991 |
Slow excitatory amino acid receptor-mediated synaptic transmission in turtle cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Cerebellum; Electric Stimulation; Kynurenic Acid; Olivary Nucleus; Purkinje Cells; Quinoxalines; Synaptic Transmission; Turtles | 1990 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
Masking effect of NMDA receptor antagonists on the formation of long-term potentiation (LTP) in superior colliculus slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Magnesium; Mice; Nerve Degeneration; Optic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Visual Cortex | 1990 |
Excitatory amino acid-mediated transmission of inspiratory drive to phrenic motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Brain Stem; In Vitro Techniques; Inhalation; Kynurenic Acid; Motor Neurons; Phrenic Nerve; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1990 |
Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Axons; Dipeptides; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Neurotoxins; Nucleus Accumbens; Pentobarbital; Picrotoxin; Pyridostigmine Bromide; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Tubocurarine | 1990 |
Actions of excitatory amino acid antagonists on synaptic inputs to the rat medial vestibular nucleus: an electrophysiological study in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Male; Neural Pathways; Neurons, Afferent; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine; Vestibular Nuclei | 1990 |
Quinoxalines interact with the glycine recognition site of NMDA receptors: studies in guinea-pig myenteric plexus and in rat cortical membranes.
Topics: Animals; Cerebral Cortex; Glycine; Guinea Pigs; In Vitro Techniques; Ion Channels; Kinetics; Kynurenic Acid; Male; Myenteric Plexus; Quinoxalines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
Neuroactive sulphur amino acids evoke a calcium-dependent transmitter release from cultured neurones that is sensitive to excitatory amino acid receptor antagonists.
Topics: Amino Acids; Amino Acids, Sulfur; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Kynurenic Acid; Mice; Neurons; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors.
Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Biological Assay; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Xenopus laevis | 1989 |
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
Quisqualate neurotoxicity: a delayed, CNQX-sensitive process triggered by a CNQX-insensitive mechanism in young rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Hippocampus; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter | 1989 |
Primary afferent depolarization in the rat spinal cord is mediated by pathways utilising NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; In Vitro Techniques; Kynurenic Acid; Neurons, Afferent; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Excitatory amino acid-mediated components of synaptically evoked input from dorsal roots to deep dorsal horn neurons in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Magnesium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots | 1989 |
Two pharmacological classes of quisqualate-induced electrical responses in rat retinal ganglion cells in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Retina; Retinal Ganglion Cells | 1989 |
Responses of spinal dorsal horn neurones evoked by myelinated primary afferent stimulation are blocked by excitatory amino acid antagonists acting at kainate/quisqualate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Animals, Newborn; Anterior Horn Cells; Electric Stimulation; Evoked Potentials; Kynurenic Acid; Myelin Sheath; Neurons, Afferent; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Spinal Cord | 1989 |
Effects of CNQX, APB, PDA, and kynurenate on horizontal cells of the tiger salamander retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; Photoreceptor Cells; Pipecolic Acids; Quinoxalines; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina; Urodela | 1989 |
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Interaction between substance P and excitatory amino acid receptors in modulation of nociceptive responses of cat spinal dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electric Stimulation; Homocysteine; Ketamine; Kynurenic Acid; Muscles; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptors; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P; Sural Nerve | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission | 1994 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
NMDA and non-NMDA receptors on rat supraoptic nucleus neurons activated monosynaptically by olfactory afferents.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Female; Kynurenic Acid; Male; Neurons; Neurons, Afferent; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Synapses | 1995 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites.
Topics: Animals; Binding Sites; Brain; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Electrophysiology; Female; Glycine; Kynurenic Acid; Neurons; Oocytes; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; RNA, Messenger; Transcription, Genetic; Xenopus laevis | 1995 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
The NMDA receptor complex modulates clonidine-induced increases in growth hormone levels in rats.
Topics: Animals; Clonidine; Growth Hormone; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Glycine site NMDA receptor antagonists provide protection against ischemia-induced neuronal damage in hippocampal slice cultures.
Topics: Animals; Brain Ischemia; Cell Death; Dizocilpine Maleate; Glycine; Glycine Agents; Hippocampus; Kynurenic Acid; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
Neuronal excitation by angiotensin II in the rostral ventrolateral medulla of the rat in vitro.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Biphenyl Compounds; Brimonidine Tartrate; Evoked Potentials; Imidazoles; In Vitro Techniques; Kynurenic Acid; Losartan; Medulla Oblongata; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors | 1995 |
Localized excitatory synaptic interactions mediate the sustained depolarization of electrographic seizures in developing hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dendrites; Evoked Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Pyramidal Tracts; Quinoxalines; Rats; Seizures; Synapses; Tetrodotoxin | 1993 |
Contribution of NMDA receptors to tetanus-induced increase in postsynaptic Ca2+ in visual cortex of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channel Blockers; Electric Stimulation; Evoked Potentials; Female; Fluorescent Dyes; Heterocyclic Compounds, 3-Ring; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Male; Microscopy, Fluorescence; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Synapses; Visual Cortex | 1993 |
Blockade of the locomotor stimulant effects of cocaine and methamphetamine by glutamate antagonists.
Topics: Amino Acids; Animals; Cocaine; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Methamphetamine; Mice; Motor Activity; Pyrrolidinones; Quinoxalines | 1993 |
Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Brain Stem; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Microelectrodes; Neurons; Neurotransmitter Agents; Quinoxalines; Rats; Sodium | 1993 |
Synaptic physiology of horizontal afferents to layer I in slices of rat SI neocortex.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Synapses; Synaptic Transmission | 1994 |
Chemical modulation of synaptic transmission in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Muscarine; Quinoxalines; Rats; Receptors, Dopamine D2; Receptors, GABA-B; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1993 |
Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cerebral Cortex; Dizocilpine Maleate; Energy Metabolism; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; Kynurenic Acid; Neurotoxins; Phosphocreatine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
Role of excitatory amino acids in brainstem activation of spinal locomotor networks in larval lamprey.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Stem; Kynurenic Acid; Lampreys; Larva; Locomotion; Nerve Net; Quinoxalines; Receptors, Amino Acid; Spinal Cord; Stimulation, Chemical | 1994 |
Anoxia selectively depresses excitatory synaptic transmission in hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1994 |
The non-NMDA subtype of excitatory amino acid receptor plays the major role in control of cardiovascular function by the subretrofacial nucleus in cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cats; Female; Glutamine; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Piperazines; Quinoxalines; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate | 1994 |
Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate.
Topics: Animals; Brain Edema; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Energy Metabolism; Glutamic Acid; Kynurenic Acid; Magnetic Resonance Spectroscopy; Organ Size; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Sodium Channels | 1994 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
Pharmacological isolation and characterization of NMDA receptor-mediated synaptic potential in the dentate gyrus of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Evidence that the parafascicular projection to the subthalamic nucleus is glutamatergic.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Electric Stimulation; Glutamates; Histocytochemistry; Kynurenic Acid; Male; Neural Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thalamic Nuclei | 1993 |
Retrotrapezoid nucleus glutamate receptors: control of CO2-sensitive phrenic and sympathetic output.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Carbon Dioxide; Cats; Decerebrate State; Electrophysiology; Female; Kynurenic Acid; Male; Medulla Oblongata; Phrenic Nerve; Quinoxalines; Receptors, Glutamate; Respiration; Sympathetic Nervous System | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
Electrophysiological identification of horizontal synaptic connections in rat visual cortex in vitro.
Topics: Animals; Baclofen; Calcium; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Magnesium; Quinoxalines; Rats; Receptors, GABA-B; Synapses; Synaptic Transmission; Visual Cortex | 1993 |
Excitatory amino acid receptor-stimulated phosphoinositide turnover in primary cerebrocortical cultures.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cycloleucine; Female; GTP-Binding Proteins; Kynurenic Acid; Pertussis Toxin; Phosphatidylinositols; Piperazines; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 1993 |
Excitatory amino acid receptor antagonists and naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Mice; Morphine Dependence; Naloxone; Quinoxalines; Receptors, Amino Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substance Withdrawal Syndrome | 1993 |
Cardiovascular responses to global cerebral ischemia: role of excitatory amino acids in the ventrolateral medullary pressor area.
Topics: Acetylcholine; Amino Acids; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Blood Pressure; Brain Ischemia; Dose-Response Relationship, Drug; Glutamates; Heart Rate; Kainic Acid; Kynurenic Acid; Male; Medulla Oblongata; Muscimol; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Vasopressin; Vasopressins | 1993 |
Effects of glutamic acid and related agents on horizontal cells in a marine teleost retina.
Topics: Animals; Aspartic Acid; Dark Adaptation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fishes; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Photoreceptor Cells; Quinoxalines; Receptors, Glutamate; Retina | 1996 |
Olfactory nerve stimulation activates rat mitral cells via NMDA and non-NMDA receptors in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Olfactory Nerve; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1996 |
Effects of parallel fiber stimulation on neurons of rat dorsal cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Cochlea; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Kynurenic Acid; Male; Nerve Fibers; Quinoxalines; Rats; Rats, Sprague-Dawley | 1996 |
Differential effects of five glycine site antagonists on NMDA receptor desensitisation.
Topics: Animals; Benzothiadiazines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biguanides; Brain Mapping; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Kynurenic Acid; Lung; Male; N-Methylaspartate; Nerve Fibers; Neurons; Pressoreceptors; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus; Vagus Nerve | 1996 |
Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Felbamate; Female; Injections, Intraventricular; Ion Channel Gating; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; Motor Activity; Phenylcarbamates; Potassium Channels; Propylene Glycols; Quinoxalines | 1996 |
Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
Topics: Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Oocytes; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 1997 |
Transporters buffer synaptically released glutamate on a submillisecond time scale.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamic Acid; Hippocampus; Kinetics; Kynurenic Acid; Lithium; Models, Neurological; Neurons; Quinoxalines; Rats; Receptors, AMPA; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors | 1997 |
Estimation of the relative potency of two glycine antagonists on NMDA-induced depolarizations in BRSC and ARCS.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 1997 |
Ultrastructural and biochemical studies on the neuroprotective effects of excitatory amino acid antagonists in the ischemic rat retina.
Topics: Animals; Choline O-Acetyltransferase; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Ischemia; Kynurenic Acid; Light; Microscopy, Electron; Neuroprotective Agents; Quinoxalines; Radiation Injuries, Experimental; Rats; Retina; Retinal Vein Occlusion; Retinal Vessels; Rose Bengal | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
The role of glutamate in swim initiation in the medicinal leech.
Topics: Animals; Electrophysiology; Esophagus; Excitatory Amino Acid Antagonists; Glutamic Acid; Interneurons; Kynurenic Acid; Leeches; Motor Activity; Neural Pathways; Quinoxalines; Spider Venoms; Swimming; Synapses | 1995 |
Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation.
Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Hippocampus; Kynurenic Acid; Male; Muscimol; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Seizures | 1998 |
Cerebellar vascular and synaptic responses in normal mice and in transgenics with Purkinje cell dysfunction.
Topics: Action Potentials; Animals; Blood Flow Velocity; Cerebellum; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Kynurenic Acid; Laser-Doppler Flowmetry; Mice; Mice, Transgenic; Microscopy, Electron; Nitric Oxide Synthase; Nitroarginine; Purkinje Cells; Quinoxalines; Receptors, AMPA; Synapses | 1998 |
Effects of the novel tricyclic quinoxalinedione derivatives, SM-18400 and its analogs, on N-methyl-D-aspartate (NMDA) receptor-mediated synaptic transmission in the isolated neonatal rat spinal cord in vitro.
Topics: Aminoquinolines; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Serine; Spinal Cord; Synaptic Transmission | 1998 |
EAA receptors in the dorsomedial hypothalamic area mediate the cardiovascular response to activation of the amygdala.
Topics: Amygdala; Animals; Bicuculline; Brain Mapping; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Heart Rate; Kynurenic Acid; Male; Microinjections; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Time Factors | 1998 |
Longitudinal distribution of components of excitatory synaptic input to motoneurones during swimming in young Xenopus tadpoles: experiments with antagonists.
Topics: Animals; Cadmium; Convulsants; Dihydro-beta-Erythroidine; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Larva; Motor Neurons; Quinoxalines; Receptors, Nicotinic; Spinal Cord; Strychnine; Swimming; Synapses; Xenopus | 1998 |
Assessing the roles of glutamatergic and cholinergic synaptic drive in the control of fictive swimming frequency in young Xenopus tadpoles.
Topics: Animals; Cholinergic Fibers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Larva; N-Methylaspartate; Neural Inhibition; Quinoxalines; Receptors, Nicotinic; Swimming; Synapses; Xenopus | 1998 |
Sympathoexcitatory neurotransmission of the chemoreflex in the NTS of awake rats.
Topics: Animals; Benzoates; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Microinjections; Quinoxalines; Rats; Rats, Wistar; Reflex; Solitary Nucleus; Sympathetic Nervous System; Synaptic Transmission | 1999 |
Pharmacological profile of the isomers of the GluR-specific agonist ATPA.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Kynurenic Acid; Propionates; Quinoxalines; Rats; Receptors, Glutamate; Stereoisomerism | 1998 |
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Effects of puerarin against glutamate excitotoxicity on cultured mouse cerebral cortical neurons.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoflavones; Kainic Acid; Kynurenic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Glutamate | 1998 |
The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP+.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Kynurenic Acid; Microinjections; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1999 |
Electrophysiological characteristics of substantia nigra neurons in organotypic cultures: spontaneous and evoked activities.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Dopamine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Kynurenic Acid; Membrane Potentials; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2000 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium | 2001 |
Multiple rostral medullary nuclei can influence breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Electromyography; Excitatory Amino Acid Antagonists; Female; Goats; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Orchiectomy; Oxygen Consumption; Quinoxalines; Respiratory Mechanics; Respiratory Muscles; Tidal Volume; Vestibular Nuclei | 2001 |
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Animals; Atropine; Cerebral Cortex; Cobalt; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamates; Kynurenic Acid; Male; Muscarinic Antagonists; Neurons; Neurotransmitter Agents; Phentolamine; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Thalamus; Vagus Nerve; Viscera | 2001 |
Multivesicular release at climbing fiber-Purkinje cell synapses.
Topics: Animals; Biological Transport; Calcium; Dipeptides; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Kynurenic Acid; Neurotransmitter Agents; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Synapses; Synaptic Transmission | 2001 |
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Consciousness; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Kynurenic Acid; Medulla Oblongata; Microinjections; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Respiratory Mechanics | 2002 |
Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus accumbens.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats | 2002 |
Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists.
Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2003 |
Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Heart Rate; Hypothalamus; Injections; Kidney; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2003 |
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).
Topics: Amnesia; Animals; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kynurenic Acid; Male; Mice; N-Methylaspartate; Nootropic Agents; Piperazines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2003 |
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lithium; Male; Neural Conduction; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2004 |
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Herpesvirus 1, Suid; Homeostasis; In Situ Hybridization; Interneurons; Isoenzymes; Kynurenic Acid; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord; Strychnine | 2005 |
Synaptic inputs to retinal ganglion cells that set the circadian clock.
Topics: Animals; Bicuculline; Biological Clocks; Circadian Rhythm; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; Kynurenic Acid; Light; Neural Pathways; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Retinal Ganglion Cells; Rod Opsins; Strychnine; Synapses; Synaptic Transmission; Tetrodotoxin | 2006 |
The role of NMDA and non-NMDA receptors in the NTS in mediating three distinct sympathoinhibitory reflexes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Blood Pressure; Cholecystokinin; GABA Agonists; Heart Rate; Kynurenic Acid; Male; Muscimol; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Synaptic Transmission | 2007 |
Glutamatergic neurotransmission is not essential for, but plays a modulatory role in, the production of gasping in arterially-perfused adult rat.
Topics: Animals; Glutamic Acid; Kynurenic Acid; Phrenic Nerve; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration Disorders; Respiratory Mechanics; Synaptic Transmission | 2008 |
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury.
Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine | 2008 |
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Vesicles; Temperature; Tetrodotoxin | 2009 |
Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics.
Topics: Antibiotics, Antineoplastic; Cloning, Molecular; DNA, Bacterial; Echinomycin; Escherichia coli; Genes, Bacterial; Kynurenic Acid; Kynurenine; Magnetic Resonance Spectroscopy; Multigene Family; Optical Rotation; Peptide Synthases; Polymerase Chain Reaction; Quinoxalines; Spectrometry, Mass, Electrospray Ionization | 2011 |
Desynchronization of multivesicular release enhances Purkinje cell output.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Biophysical Phenomena; Calcium; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Linear Models; Mice; Nerve Fibers; Nerve Net; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Strontium; Synapses; Time Factors | 2011 |
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Glycogen; Hydrogen-Ion Concentration; Hypoglycemia; Kynurenic Acid; Lactic Acid; Leukoencephalopathies; Mice; Mice, Inbred C57BL; Optic Nerve Injuries; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2014 |
Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Kynurenic Acid; Macaca; Male; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Temporal Lobe; Time Factors; Visual Perception | 2015 |
Concurrent antagonism of NMDA and AMPA receptors in the ventral tegmental area reduces the expression of conditioned approach learning in rats.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Quinoxalines; Rats, Long-Evans; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Ventral Tegmental Area | 2016 |