Compounds > quinoxalines
Page last updated: 2024-08-17

quinoxalines and in 1130

quinoxalines has been researched along with in 1130 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Chang, KT; Kim, DK; Kim, YK; Kim, YW; Lee, HJ; Lee, JY; Sheen, YY1
Kim, DK; Kim, YK; Kim, YW; Sheen, YY1
Hong, JH; Kim, DK; Kim, IY; Kim, SJ; Kwak, C; Lee, GT; Mueller, TJ; Sheen, YY; Watson, JA1
Choi, MJ; Han, JY; Hong, SS; Jin, HR; Kim, DK; Kim, IH; Kim, SJ; Kim, WJ; Lee, CR; Lee, SJ; Mamura, M; Park, SH; Piao, S; Ryu, JK; Shin, HY; Suh, JK; Zhang, LW1
Chevalier, RL; Forbes, MS; Galarreta, CI; Kim, DK; Simpkins, LN; Thornhill, BA1
Kim, DK; Min, KN; Nam, JS; Park, CY; Park, SY; Sheen, YY; Son, JY1
Avan, A; Binabaj, MM; Ferns, GA; Hassanian, SM; Khazaei, M; Khoshakhlagh, M; Soleimani, A1
Aishima, S; Anzai, K; Eguchi, Y; Imajo, K; Itoh, Y; Kage, M; Moriguchi, M; Nakajima, A; Oeda, S; Ogawa, Y; Seko, Y; Takahashi, H; Yoneda, M1

Reviews

1 review(s) available for quinoxalines and in 1130

ArticleYear
Therapeutic potential of pharmacological TGF-β signaling pathway inhibitors in the pathogenesis of breast cancer.
    Biochemical pharmacology, 2019, Volume: 164

    Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Imidazoles; Quinoxalines; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2019

Other Studies

7 other study(ies) available for quinoxalines and in 1130

ArticleYear
Pharmacokinetics and tissue distribution of 3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide; a novel ALK5 inhibitor and a potential anti-fibrosis drug.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:3

    Topics: Administration, Oral; Animals; Benzamides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dogs; Enzyme Inhibitors; Half-Life; Haplorhini; Humans; Imidazoles; Injections, Intravenous; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Models, Biological; Protein Serine-Threonine Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Tissue Distribution

2008
Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Haplorhini; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Proadifen; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinoxalines; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Species Specificity

2008
Effect of IN-1130, a small molecule inhibitor of transforming growth factor-beta type I receptor/activin receptor-like kinase-5, on prostate cancer cells.
    The Journal of urology, 2008, Volume: 180, Issue:6

    Topics: Animals; Drug Screening Assays, Antitumor; Humans; Imidazoles; Male; Mice; Prostatic Neoplasms; Quinoxalines; Tumor Cells, Cultured

2008
IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease.
    The journal of sexual medicine, 2009, Volume: 6, Issue:5

    Topics: Animals; Disease Models, Animal; Fibrosis; Humans; Imidazoles; Male; Penile Induration; Penis; Protein Kinase Inhibitors; Quinoxalines; Rats

2009
Transforming growth factor-β1 receptor inhibition preserves glomerulotubular integrity during ureteral obstruction in adults but worsens injury in neonatal mice.
    American journal of physiology. Renal physiology, 2013, Mar-01, Volume: 304, Issue:5

    Topics: Age Factors; Animals; Animals, Newborn; Imidazoles; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Quinoxalines; Receptors, Transforming Growth Factor beta; Ureteral Obstruction

2013
An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.
    Cancer letters, 2014, Aug-28, Volume: 351, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Nucleus; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Female; Humans; Imidazoles; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Protein Serine-Threonine Kinases; Protein Transport; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Tumor Burden

2014
Accuracy of liver stiffness measurement and controlled attenuation parameter using FibroScan
    Journal of gastroenterology, 2020, Volume: 55, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Area Under Curve; Aspartate Aminotransferases; Biopsy; Body Mass Index; Elasticity Imaging Techniques; Female; gamma-Glutamyltransferase; Humans; Imidazoles; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Quinoxalines; ROC Curve; Young Adult

2020