Page last updated: 2024-08-17

quinoxalines and hydrazine

quinoxalines has been researched along with hydrazine in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.57)	18.7374
1990's	11 (19.64)	18.2507
2000's	24 (42.86)	29.6817
2010's	15 (26.79)	24.3611
2020's	4 (7.14)	2.80

Authors

Authors	Studies
Mokhtar, HM	1
Faccini, JM; Ferrando, R; Monro, AM; Truhaut, R	1
Hirose, T; Iwata, T; Nakamura, M; Yamaguchi, M	1
Grayeski, ML; Sandmann, BW	1
Branka, JE; Jarry, A; Laboisse, CL; Vallette, G	1
Katusic, ZS; Onoue, H	1
Gordge, MP; Hothersall, JS; Noronha-Dutra, AA	1
Homer, K; Wanstall, J	1
Frölich, JC; Ikic, M; Raida, M; Tewes, KS; Tsikas, D	1
Fiore, SA; Homer, KL; Wanstall, JC	1
Rehder, V; Van Wagenen, S	1
Diamond, J; Sandirasegarane, L	1
Alonso-Galicia, M; Harder, DR; Hudetz, AG; Roman, RJ; Shen, H	1
Berkels, R; Klaus, W; Roesen, R; Suerhoff, S	1
Anraku, M; Ichinose, M; Sawada, M	1
Aldinucci, C; Benocci, A; Frosini, M; Meini, A; Palmi, M; Pessina, G; Sgaragli, G; Youmbi, GT	1
Eguchi, D; Katusic, ZS	1
Castel, H; Vaudry, H	1
Allescher, HD; Geisler, F; Neuhuber, WL; Schusdziarra, V; Storr, M	1
Bon, CL; Garthwaite, J	1
Allescher, HD; Folmer, R; Kurjak, M; Schusdziarra, V; Storr, M	1
Gödecke, A; Nawrath, H; Schrader, J; Wegener, JW	1
Homer, KL; Wanstall, JC	1
Ishikawa, T; Kaneko, Y; Nakayama, K; Sugino, F	1
Dallemagne, P; Guie, MA; Guillon, J; Jarry, C; Leger, JM; Massip, S; Reynolds, RC	1
Butini, S; Campiani, G; Chiasserini, L; Fattorusso, C; Gemma, S; Kukreja, G; Locatelli, GA; Maga, G; Nacci, V; Novellino, E; Persico, M; Romano, MP; Savini, L; Spadari, S	1
Cao, S; Chatterjee, S; Farrugia, G; Gadgil, J; Gibbons, SJ; Langer, DA; Perri, RE; Shah, VH	1
Espey, MG; Isenberg, JS; Ridnour, LA; Roberts, DD; Thomas, DD; Wink, DA	1
Bennett, VJ; Papaconstandinou, NA; Reynolds, IJ; Rintoul, GL	1
Amatore, C; Arbault, S; Cauli, B; Geoffroy, H; Guille, M; Hamel, E; Rancillac, A; Rossier, J; Tong, XK	1
Aiello, F; Brizzi, A; Garofalo, A; Grande, F; Grazia, OD; Neamati, N	1
Arrigoni, E; Rosenberg, PA	1
Favaloro, JL; Irvine, JC; Kemp-Harper, BK; Widdop, RE	1
Bakker, LM; Chaytor, AT; Edwards, DH; Griffith, TM	1
Bagcivan, I; Berkan, O; Doğan, K; Kaya, T; Yildirim, K; Yildirim, S	1
Canalli, AA; Conran, N; Costa, FF; Franco-Penteado, CF; Saad, ST	1
Aiello, F; Cao, X; Garofalo, A; Grande, F; Neamati, N; Oshima, T; Plasencia, C; Sanchez, T; Yamada, R	1
Hedenstierna, G; Hjoberg, J; Jonasson, S	1
Aldana, I; Ancizu, S; Barea, C; Galiano, S; Monge, A; Moreno, E; Pérez-Silanes, S; Torres, E	1
Hebar, A; Rütgen, BC; Selzer, E	1
Debnath, B; Garofalo, A; Grande, F; Imada, T; Masuda, M; Neamati, N; Oshima, T; Xu, S	1
Garofalo, A; Grande, F; Neamati, N; Xu, S	1
Frink, TJ; Kadowitz, PJ; Lasker, GF; Pankey, EA; Walter, KA; Zeitzer, JR	1
de Souza, MV; Gomes, LR; Low, JN; Noguiera, TC; Pinheiro, AC; Rodrigues, AS; Wardell, JL	1
Adisetiyo, H; Garofalo, A; Grande, F; Neamati, N; Roy-Burman, P; Tamura, S; Xu, S	1
Aiello, F; Garofalo, A; Grande, F; Neamati, N	1
Aldana, I; Barea, C; Deharo, E; Galiano, S; Pabón, A; Quiliano, M; Ramirez-Calderon, G	1
Guan, M; Li, N; Song, J; Sun, S; Wang, R; Zhang, J; Zhang, X; Zhao, Z	1
Chai, EPZ; Ham, S; Krumeich, S; Lima, LG; Lobb, RJ; Möller, A; Muller, A; Wen, SW; Wiegmans, AP	1
Arnold, MA; Bid, HK; Brandolini, L; Cam, H; Cam, M; Gross, AC; Hinckley, JM; Houghton, PJ; London, CA; Mo, X; Phelps, DA; Roberts, RD; Saraf, AJ; Winget, SA	1
Ji, S; Pang, L; Xing, J	1
He, S; Li, X; Martin, DT; Tian, Y; Weiss, RM	1
Heath, BR; Hong, L; Lei, YL; Ljungman, M; Lu, T; Neamati, N; Shrestha, B; Tang, J	1
Hashimoto, H; Hisamitsu, S; Ishii, G; Ishii, T; Kinoshita, T; Kuwata, T; Mitsunaga, S; Ochiai, A; Ohara, Y; Shitara, K; Suzuki, A; Yanagihara, K; Yoshino, T	1
Fu, JX; Ju, SG; Li, J; Ling, HY; Sun, Y; Wang, PJ; Yang, Z	1
Tian, RG; Tian, SK; Xie, D; Zhang, XT	1

Reviews

1 review(s) available for quinoxalines and hydrazine

Article	Year
Identification and Preclinical Evaluation of SC144, a Novel Pyrroloquinoxaline Derivative with Broad-Spectrum Anticancer Activity. Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:8 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Drug Discovery; Humans; Hydrazines; Molecular Structure; Neoplasms; Quinoxalines	2016

Other Studies

55 other study(ies) available for quinoxalines and hydrazine

Article	Year
Hydrazine and quinoxaline derivatives of aryl L-ascorbic acid analogs. Die Pharmazie, 1978, Volume: 33, Issue:11 Topics: Ascorbic Acid; Chemical Phenomena; Chemistry; Hydrazines; Oxidation-Reduction; Quinoxalines	1978
Negative results of carcinogenicity bioassay of methyl carbazate in rats: significance for the toxicological evaluation of carbadox. Toxicology, 1981, Volume: 22, Issue:3 Topics: Animals; Biological Assay; Carbadox; Carcinogens; Female; Hydrazines; Male; Quinoxalines; Rats; Rats, Inbred Strains	1981
Determination of urinary glucuronide conjugates by high-performance liquid chromatography with pre-column fluorescence derivatization. Journal of chromatography. B, Biomedical applications, 1994, Apr-01, Volume: 654, Issue:2 Topics: Adult; Androsterone; Chromatography, High Pressure Liquid; Etiocholanolone; Female; Glucuronates; Humans; Hydrazines; Indicators and Reagents; Male; Quinoxalines; Spectrometry, Fluorescence	1994
Quinoxalinone derivatization of biological carboxylic acids for detection by peroxyoxalate chemiluminescence with high-performance liquid chromatography. Journal of chromatography. B, Biomedical applications, 1994, Mar-04, Volume: 653, Issue:2 Topics: Animals; Carboxylic Acids; Cattle; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hydrazines; Luminescent Measurements; Oxalates; Quinoxalines; Reproducibility of Results; Valproic Acid	1994
Stimulation of mucin exocytosis from human epithelial cells by nitric oxide: evidence for a cGMP-dependent and a cGMP-independent pathway. The Biochemical journal, 1997, Apr-15, Volume: 323 ( Pt 2) Topics: 1-Methyl-3-isobutylxanthine; Cyclic GMP; Cysteine; Enzyme Inhibitors; Epithelium; Exocytosis; Guanylate Cyclase; Humans; Hydrazines; Mucins; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Reactive Oxygen Species; Superoxide Dismutase	1997
The effect of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide. Brain research, 1998, Feb-23, Volume: 785, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bradykinin; Cerebral Arteries; Charybdotoxin; Colforsin; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Uridine Triphosphate	1998
Evidence for a cyclic GMP-independent mechanism in the anti-platelet action of S-nitrosoglutathione. British journal of pharmacology, 1998, Volume: 124, Issue:1 Topics: Cell Membrane; Cyclic AMP; Cyclic GMP; Glutathione; Humans; Hydrazines; In Vitro Techniques; Nitric Oxide; Nitrogen Oxides; Nitroso Compounds; Oxadiazoles; Phenanthrolines; Platelet Aggregation Inhibitors; Quinoxalines; S-Nitrosoglutathione; Sulfhydryl Compounds	1998
In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary arteries. European journal of pharmacology, 1998, Aug-28, Volume: 356, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Male; Mutagens; Nitric Oxide; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; Spermine; Vasodilation; Vasodilator Agents	1998
Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets. FEBS letters, 1999, Jan-15, Volume: 442, Issue:2-3 Topics: Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Cyclic GMP; Cysteine; Fatty Acids, Unsaturated; Glutathione; Guanylate Cyclase; Humans; Hydrazines; Inhibitory Concentration 50; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Thromboxane A2	1999
Inhibition by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) of responses to nitric oxide-donors in rat pulmonary artery: influence of the mechanism of nitric oxide generation. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; Spermine; Vasodilation	1999
Regulation of neuronal growth cone filopodia by nitric oxide. Journal of neurobiology, 1999, Volume: 39, Issue:2 Topics: Animals; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Cones; Guanylate Cyclase; Hydrazines; Molsidomine; Mutagens; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Pseudopodia; Quinoxalines; Snails; Sulfhydryl Reagents	1999
The nitric oxide donors, SNAP and DEA/NO, exert a negative inotropic effect in rat cardiomyocytes which is independent of cyclic GMP elevation. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:4 Topics: Animals; Cardiotonic Agents; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Penicillamine; Quinoxalines; Rats; Rats, Wistar	1999
Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation. Stroke, 1999, Volume: 30, Issue:12 Topics: Adenosine; Alkaloids; Amides; Animals; Basilar Artery; Carbazoles; Cerebrovascular Circulation; Cyclic GMP; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydroxyeicosatetraenoic Acids; Indoles; Male; Microcirculation; Middle Cerebral Artery; Mixed Function Oxygenases; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sulfones; Vasodilation; Vasodilator Agents	1999
Nitric oxide causes a cGMP-independent intracellular calcium rise in porcine endothelial cells-a paradox? Microvascular research, 2000, Volume: 59, Issue:1 Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; Hydrazines; Imidazoles; Intracellular Fluid; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Penicillamine; Quinoxalines; Spectrophotometry, Ultraviolet; Swine; Triazenes	2000
Inhibition of the glutamate-induced K(+) current in identified Onchidium neurons by nitric oxide donors. Journal of neuroscience research, 2000, Jun-01, Volume: 60, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Cyclic GMP; Enzyme Inhibitors; Ganglia, Invertebrate; Glutamic Acid; Hydrazines; Mollusca; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Potassium Channels; Quinoxalines; Vasodilator Agents	2000
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24 Topics: Aminoquinolines; Animals; Arginine; Astrocytoma; Calcium; Corpus Striatum; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heparin; Humans; Hydrazines; In Vitro Techniques; Interleukin-1; Intracellular Fluid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Spermine; Tumor Cells, Cultured	2000
Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Calcium; Colforsin; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrazines; In Vitro Techniques; Indomethacin; Ionophores; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Potassium Chloride; Quinoxalines; Saphenous Vein; Vasoconstrictor Agents; Vasodilation	2001
Nitric oxide directly activates GABA(A) receptor function through a cGMP/protein kinase-independent pathway in frog pituitary melanotrophs. Journal of neuroendocrinology, 2001, Volume: 13, Issue:8 Topics: Aminoquinolines; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dithionitrobenzoic Acid; Electric Conductivity; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hydrazines; Ion Channel Gating; Male; Melanocytes; Membrane Potentials; Mercaptoethanol; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Oxidation-Reduction; Patch-Clamp Techniques; Pituitary Gland; Quinoxalines; Rana ridibunda; Receptors, GABA-A; Sulfhydryl Reagents	2001
Characterization of vagal input to the rat esophageal muscle. Autonomic neuroscience : basic & clinical, 2001, Aug-13, Volume: 91, Issue:1-2 Topics: Animals; Atropine; Enteric Nervous System; Enzyme Inhibitors; Esophagus; Galanin; Gastrointestinal Agents; Hexamethonium; Hydrazines; Male; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Nicotinic Antagonists; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Oxadiazoles; Parasympatholytics; Quinoxalines; Rats; Rats, Wistar; Serotonin; Tetrodotoxin; Tubocurarine; Vagus Nerve; Vasoactive Intestinal Peptide	2001
Exogenous nitric oxide causes potentiation of hippocampal synaptic transmission during low-frequency stimulation via the endogenous nitric oxide-cGMP pathway. The European journal of neuroscience, 2001, Volume: 14, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Cyanides; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanylate Cyclase; Hippocampus; Hydrazines; Long-Term Potentiation; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission	2001
Okadaic acid inhibits relaxant neural transmission in rat gastric fundus in vitro. Acta physiologica Scandinavica, 2002, Volume: 175, Issue:1 Topics: Animals; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Gastrointestinal Agents; Hydrazines; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Okadaic Acid; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Purinones; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide	2002
Effects of nitric oxide donors on cardiac contractility in wild-type and myoglobin-deficient mice. British journal of pharmacology, 2002, Volume: 136, Issue:3 Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Female; Hydrazines; In Vitro Techniques; Male; Mice; Myocardial Contraction; Myocardium; Myoglobin; Nitric Oxide Donors; Nitrogen Oxides; Nitroso Compounds; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine	2002
Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: Adenosine Diphosphate; Animals; Catalase; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Indazoles; Male; Nitric Oxide Donors; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Superoxide Dismutase; Thapsigargin; Thionucleotides; Vasoconstriction	2002
Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells. Journal of pharmacological sciences, 2003, Volume: 91, Issue:1 Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cytosol; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucose; Hydrazines; Hypoglycemic Agents; Islets of Langerhans; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Tolbutamide	2003
Synthesis and preliminary in vitro evaluation of antimycobacterial activity of new pyrrolo[1,2-a] quinoxaline-carboxylic acid hydrazide derivatives. Journal of enzyme inhibition and medicinal chemistry, 2004, Volume: 19, Issue:6 Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Carboxylic Acids; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Crystallography, X-Ray; Drug Evaluation, Preclinical; Hydrazines; In Vitro Techniques; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Quinoxalines; Stereoisomerism; Structure-Activity Relationship; Vero Cells	2004
Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663. Biochemistry, 2005, Jul-19, Volume: 44, Issue:28 Topics: Adenosine Triphosphate; Antiviral Agents; Binding Sites; Binding, Competitive; DNA, Viral; Enzyme Inhibitors; Hepacivirus; Hydrazines; Hydrolysis; Molecular Mimicry; Pyrazines; Quinolines; Quinoxalines; RNA Helicases; Substrate Specificity; Viral Nonstructural Proteins	2005
Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation. American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:3 Topics: Adenoviridae; Animals; Calcium Signaling; Cell Line; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; Hydrazines; Hypertension, Portal; Liver; Male; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Transduction, Genetic	2006
Guanylyl cyclase-dependent chemotaxis of endothelial cells in response to nitric oxide gradients. Free radical biology & medicine, 2006, Mar-15, Volume: 40, Issue:6 Topics: Cell Movement; Cells, Cultured; Chemotaxis; Diffusion; Endothelial Cells; Endothelium, Vascular; Guanylate Cyclase; Humans; Hydrazines; Neovascularization, Physiologic; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Triazenes; Volatilization	2006
Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential. Journal of neurochemistry, 2006, Volume: 97, Issue:3 Topics: Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Hydrazines; Membrane Potentials; Mitochondria; Movement; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Prosencephalon; Quinoxalines; Rats; Time Factors	2006
Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jun-28, Volume: 26, Issue:26 Topics: Animals; Cerebellum; Cerebrovascular Circulation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Hydrazines; In Vitro Techniques; Male; Microcirculation; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation	2006
Synthesis and antitumor activities of a series of novel quinoxalinhydrazides. Bioorganic & medicinal chemistry, 2007, Jan-01, Volume: 15, Issue:1 Topics: Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Hydrazines; Molecular Structure; Quinoxalines; Stereoisomerism; Structure-Activity Relationship	2007
Nitric oxide-induced adenosine inhibition of hippocampal synaptic transmission depends on adenosine kinase inhibition and is cyclic GMP independent. The European journal of neuroscience, 2006, Volume: 24, Issue:9 Topics: Adenosine; Adenosine Kinase; Animals; Cyclic GMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Hydrazines; Male; Nitric Oxide; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Thionucleotides; Xanthines	2006
Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4 Topics: Animals; Aorta, Thoracic; Benzoates; Cyclic GMP-Dependent Protein Kinases; Cysteine; Drug Tolerance; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Imidazoles; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Time Factors; Vasodilation	2007
Modulation of gap-junction-dependent arterial relaxation by ascorbic acid. Journal of vascular research, 2007, Volume: 44, Issue:5 Topics: Animals; Ascorbic Acid; Boron Compounds; Connexin 43; Connexins; Dose-Response Relationship, Drug; Endothelium, Vascular; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Gap Junctions; Hydrazines; Iliac Artery; Indoles; Indomethacin; Male; Membrane Potentials; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside; Oxadiazoles; Phenylephrine; Quinoxalines; Rabbits; Vasodilation	2007
Investigation of the vasorelaxant effects of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) and diethylamine/nitric oxide (DEA/NO) on the human radial artery used as coronary bypass graft. Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:5 Topics: Aged; Analysis of Variance; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Female; Humans; Hydrazines; In Vitro Techniques; Indazoles; Male; Middle Aged; Nitric Oxide Donors; Oxadiazoles; Peptides; Phenylephrine; Potassium Channels, Calcium-Activated; Quinoxalines; Radial Artery; Vasoconstrictor Agents; Vasodilation	2007
Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation. Haematologica, 2008, Volume: 93, Issue:4 Topics: Adult; alpha-Thalassemia; Anemia, Sickle Cell; CD11a Antigen; CD11b Antigen; Cell Adhesion; Cyclic GMP; Endothelial Cells; Female; Fibronectins; Humans; Hydrazines; Hydroxyurea; Integrin alpha4; Intercellular Adhesion Molecule-1; Male; Middle Aged; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Pyrazoles; Pyridines; Quinoxalines; Sickle Cell Trait	2008
Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity. Cancer biology & therapy, 2009, Volume: 8, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Discovery; Female; Flow Cytometry; HT29 Cells; Humans; Hydrazines; Inhibitory Concentration 50; Mice; Mice, Nude; Molecular Structure; Neoplasms; Quinoxalines; Xenograft Model Antitumor Assays	2009
Concomitant administration of nitric oxide and glucocorticoids improves protection against bronchoconstriction in a murine model of asthma. Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 109, Issue:2 Topics: Administration, Inhalation; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Glucocorticoids; Guanylate Cyclase; Hydrazines; Hydrocortisone; Injections, Intraperitoneal; Lipopolysaccharides; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Ovalbumin; Oxadiazoles; Pneumonia; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Respiration, Artificial; Respiratory Mechanics; Soluble Guanylyl Cyclase	2010
New 1,4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterium tuberculosis agents. Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12 Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Chlorocebus aethiops; Hydrazines; Inhibitory Concentration 50; Isonicotinic Acids; Molecular Structure; Mycobacterium tuberculosis; Quinoxalines; Vero Cells	2011
NVX-412, a new oncology drug candidate, induces S-phase arrest and DNA damage in cancer cells in a p53-independent manner. PloS one, 2012, Volume: 7, Issue:9 Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cell Shape; Cell Size; DNA Damage; DNA Replication; Drug Screening Assays, Antitumor; Humans; Hydrazines; Inhibitory Concentration 50; Neoplasms; Phosphorylation; Quinoxalines; S Phase Cell Cycle Checkpoints; Tumor Suppressor Protein p53	2012
Stabilization of MDA-7/IL-24 for colon cancer therapy. Cancer letters, 2013, Jul-28, Volume: 335, Issue:2 Topics: Aged; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Down-Regulation; fas Receptor; Female; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazines; Interleukins; Male; Molecular Docking Simulation; Prognosis; Quinoxalines; Recombinant Proteins; Survival; Tumor Suppressor Protein p53; Up-Regulation	2013
Discovery of a novel orally active small-molecule gp130 inhibitor for the treatment of ovarian cancer. Molecular cancer therapeutics, 2013, Volume: 12, Issue:6 Topics: Administration, Oral; Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cytokine Receptor gp130; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Interleukin-6; Mice; Ovarian Neoplasms; Phosphorylation; Quinoxalines; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays	2013
The sGC activator BAY 60-2770 has potent erectile activity in the rat. American journal of physiology. Heart and circulatory physiology, 2013, Jun-15, Volume: 304, Issue:12 Topics: Animals; Benzoates; Biphenyl Compounds; Blood Pressure; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydrocarbons, Fluorinated; Injections; Male; Nerve Crush; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Penile Erection; Penis; Peripheral Nerves; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase	2013
Comparison of the structure of (E)-2-(2-benzylidenehydrazinylidene)quinoxaline with those of its chloro- and bromobenzylidene analogues. Acta crystallographica. Section C, Crystal structure communications, 2013, Volume: 69, Issue:Pt 8 Topics: Crystallography, X-Ray; Hydrazines; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Quinoxalines	2013
Dual inhibition of survivin and MAOA synergistically impairs growth of PTEN-negative prostate cancer. British journal of cancer, 2015, Jul-14, Volume: 113, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Hydrazines; Inhibitor of Apoptosis Proteins; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Prostatic Neoplasms; PTEN Phosphohydrolase; Quinoxalines; Survivin	2015
New hydrazine and hydrazide quinoxaline 1,4-di-N-oxide derivatives: In silico ADMET, antiplasmodial and antileishmanial activity. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Antiprotozoal Agents; Humans; Hydrazines; Leishmania infantum; Leishmaniasis, Visceral; Malaria, Falciparum; Plasmodium falciparum; Quinoxalines; Structure-Activity Relationship	2017
Blocking gp130 signaling suppresses autotaxin expression in adipocytes and improves insulin sensitivity in diet-induced obesity. Journal of lipid research, 2017, Volume: 58, Issue:11 Topics: 3T3-L1 Cells; Adipocytes; Animals; Cytokine Receptor gp130; Diet; Down-Regulation; Fatty Acids, Nonesterified; Glucose; Hydrazines; Insulin Resistance; Interleukin-6; Isoxazoles; Janus Kinases; Lipolysis; Lysophospholipids; Mice; Obesity; Phosphoric Diester Hydrolases; Propionates; Quinoxalines; Signal Transduction; STAT3 Transcription Factor	2017
Breast Cancer-Derived Exosomes Alter Macrophage Polarization Frontiers in immunology, 2018, Volume: 9 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coculture Techniques; Cytokine Receptor gp130; Exosomes; Female; Hydrazines; Interleukin-6; Macrophage Activation; Macrophages; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Primary Cell Culture; Quinoxalines; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment	2018
IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis. JCI insight, 2018, 08-23, Volume: 3, Issue:16 Topics: Adolescent; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Child; Cytokine Receptor gp130; Drug Evaluation, Preclinical; Follow-Up Studies; Humans; Hydrazines; Interleukin-6; Interleukin-8; Lung; Lung Neoplasms; Male; Mice; Osteosarcoma; Primary Cell Culture; Quinoxalines; Receptors, Interleukin-8A; Sulfonamides; Xenograft Model Antitumor Assays; Young Adult	2018
Amiloride Alleviates Neurological Deficits Following Transient Global Ischemia and Engagement of Central IL-6 and TNF-α Signal. Current molecular medicine, 2019, Volume: 19, Issue:8 Topics: Acid Sensing Ion Channels; Amiloride; Animals; Asphyxia; Brain Damage, Chronic; Brain Edema; Caspase 3; Caspase 9; Drug Evaluation, Preclinical; Hippocampus; Hydrazines; Interleukin-6; Ischemic Attack, Transient; Male; Quinoxalines; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Up-Regulation	2019
Synergistic inhibition of GP130 and ERK signaling blocks chemoresistant bladder cancer cell growth. Cellular signalling, 2019, Volume: 63 Topics: Butadienes; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Hydrazines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Nitriles; Quinoxalines; Urinary Bladder Neoplasms	2019
Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer. Theranostics, 2020, Volume: 10, Issue:15 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Quinoxalines; RNA, Antisense; Up-Regulation	2020
Drug-exposed cancer-associated fibroblasts facilitate gastric cancer cell progression following chemotherapy. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021, Volume: 24, Issue:4 Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Movement; Fluorouracil; Gene Expression; Humans; Hydrazines; Morpholines; Oxaliplatin; Quinoxalines; Stomach; Stomach Neoplasms; Tumor Microenvironment	2021
Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway. Chemico-biological interactions, 2022, Jan-25, Volume: 352 Topics: Cell Line, Tumor; Cytokine Receptor gp130; Exosomes; Humans; Hydrazines; Immunophenotyping; Lymphoma, Large B-Cell, Diffuse; Models, Biological; Phenotype; Quinoxalines; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Tumor-Associated Macrophages	2022
Copper-catalyzed C-3 benzylation of quinoxalin-2(1 Organic & biomolecular chemistry, 2022, 06-08, Volume: 20, Issue:22 Topics: Catalysis; Copper; Hydrazines; Molecular Structure; Quinoxalines	2022