quinoxalines and enkephalin, ala(2)-mephe(4)-gly(5)-

Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Analgesics; Brimonidine Tartrate; Bucladesine; Calcium; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cytosol; Edetic Acid; Egtazic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Quinoxalines; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine

Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses

Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Barium; Bicuculline; Dendrites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Ion Channel Gating; Naloxone; Nerve Endings; Potassium Channels; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Medulla Oblongata; Morphine; Neurons; Quinoxalines; Rats

Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Choline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Neurotransmitter Uptake Inhibitors; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Opioid, mu; Substance P; Synaptic Transmission

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; In Vitro Techniques; Indoles; Membrane Potentials; Neurons; Quinoxalines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron

Topics: Animals; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Naloxone; Narcotics; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Peptides; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin

Topics: Analgesics; Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Microinjections; Pain; Phenazocine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Serotonin Receptor Agonists

Topics: Animals; Brimonidine Tartrate; Calcium Channels; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Locus Coeruleus; Morphine; Narcotics; Potassium Channels; Quinoxalines

Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, Spinal; Animals; Behavior, Animal; Brimonidine Tartrate; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hot Temperature; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain Measurement; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance P

Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Hippocampus; Kinetics; Membrane Potentials; Naloxone; Neurons; Nimodipine; Oscillometry; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Tetrodotoxin; Time Factors

Topics: Animals; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Morphine; Narcotics; Neurosecretory Systems; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Supraoptic Nucleus; Synaptic Transmission

Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Autopsy; Brain; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Opioid-Related Disorders; Postmortem Changes; Quinoxalines; Receptors, Opioid, mu; Reference Values; Sulfur Radioisotopes

Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Autonomic Denervation; Benzeneacetamides; Brimonidine Tartrate; Cell Fractionation; Colon; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Pertussis Toxin; Pyrrolidines; Quinoxalines; Receptors, Opioid; Synaptosomes; Virulence Factors, Bordetella

Topics: Animals; Cell Count; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Green Fluorescent Proteins; Hormone Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Narcotics; Neurons; Patch-Clamp Techniques; Pro-Opiomelanocortin; Proglumide; Proto-Oncogene Proteins c-fos; Quinoxalines; Solitary Nucleus; Time Factors; Visceral Afferents

Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Benzeneacetamides; Blotting, Western; Brimonidine Tartrate; Desipramine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Male; Myenteric Plexus; Peristalsis; Pyrrolidines; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synaptosomes

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Brimonidine Tartrate; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; In Vitro Techniques; Male; Neurons; Presynaptic Terminals; Pyridines; Pyrroles; Quinoxalines; Quipazine; Rats; Rats, Wistar; Septum of Brain; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

Topics: Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; Benzeneacetamides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression; Hypothalamus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naltrexone; Narcotic Antagonists; Neural Inhibition; Neurons; Patch-Clamp Techniques; Peptide Fragments; Pro-Opiomelanocortin; Pyrrolidines; Quinoxalines; Receptors, Opioid; Somatostatin; Synapses

Topics: Analgesics, Opioid; Animals; Central Amygdaloid Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Narcotic Antagonists; Neural Inhibition; Neurons; Peptides; Quinoxalines; Receptors, Opioid, mu; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine

Topics: Action Potentials; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glycine Agents; Heroin; Hyperalgesia; Inflammation; Inhibitory Postsynaptic Potentials; Male; Neurons; Pain; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Strychnine; Sucrose; Ventral Tegmental Area