quinoxalines has been researched along with eapb0503 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bompart, J; Bonnet, PA; Bressolle, FM; Cooper, JF; Deleuze-Masquéfa, C; El Messaoudi, S; Gattacceca, F; Khier, S; Lafaille, F; Pinguet, F; Solassol, I | 1 |
| Bertrand, B; Bonnet, PA; Bressolle, FM; Deleuze-Masquéfa, C; Doulain, PE; Enjalbal, C; Lafaille, F; Solassol, I; Vappiani, J | 1 |
| Bazarbachi, A; Bonnet, PA; Deleuze-Masquéfa, C; El Eit, R; Hmadi, R; Iskandarani, A; Mahon, FX; Nasr, R; Saliba, J | 1 |
| Berthier, CP; Bonnet, PA; Deleuze-Masquefa, C; El Hajj, HA; Hamie, MH; Hleihel, RS; Karam, MM; Nabbouh, AI; Saliba, JL; Tawil, NM; Wu, HJM | 1 |
| Bec, N; Constant, C; Courbet, A; Deleuze-Masquefa, C; El Messaoudi, S; Gattacceca, F; Khier, S; Larroque, C; Pugniere, M; Zghaib, Z | 1 |
| Bonnet, PA; Bressolle-Gomeni, FMM; Chouchou, A; Cuq, P; Deleuze-Masquéfa, C; Enjalbal, C; Marion, B; Roques, C | 1 |
| Bastien, P; Bonnet, PA; Bou Youness, H; El Hajj, H; El Hajj, R; Khalifeh, I; Lachaud, L; Masquefa, C | 1 |
| Bonnet, PA; Deleuze-Masquefa, C; El Hajj, H; El Hajj, R; El Sabban, M; Hamie, M; Hleihel, R; Jishi, B; Skayneh, H | 1 |
8 other study(ies) available for quinoxalines and eapb0503
| Article | Year |
|---|---|
Metabolism and pharmacokinetics of EAPB0203 and EAPB0503, two imidazoquinoxaline compounds previously shown to have antitumoral activity on melanoma and T-lymphomas.
Topics: Animals; Antineoplastic Agents; Biotransformation; Blood Proteins; Dogs; Humans; Lymphoma, T-Cell; Melanoma; Mice; Microsomes, Liver; Molecular Structure; Protein Binding; Quinoxalines; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution | 2010 |
Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chemistry, Pharmaceutical; Chromatography, Liquid; Deuterium Exchange Measurement; Dogs; Hepatocytes; Humans; Hydroxylation; Microsomes, Liver; Quinoxalines; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
EAPB0503, a novel imidazoquinoxaline derivative, inhibits growth and induces apoptosis in chronic myeloid leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitosis; Piperazines; Pyrimidines; Quinoxalines | 2014 |
Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; Flow Cytometry; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Mice; Microscopy, Confocal; Mutant Proteins; Mutation; Nuclear Proteins; Nucleophosmin; Phosphorylation; Poly(ADP-ribose) Polymerases; Quinoxalines; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2017 |
Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity.
Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Colchicine; Computer Simulation; Humans; Models, Molecular; Molecular Docking Simulation; Protein Binding; Quinoxalines; Tubulin; Tubulin Modulators | 2017 |
Liquid chromatography-electrospray ionization-tandem mass spectrometry method for quantitative estimation of new imiqualine leads with potent anticancer activities in rat and mouse plasma. Application to a pharmacokinetic study in mice.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; Liquid-Liquid Extraction; Male; Mice; Mice, Inbred C57BL; Plasma; Quinoxalines; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2018 |
EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica.
Topics: Humans; Imiquimod; Leishmania major; Leishmania tropica; Leishmaniasis, Cutaneous; NF-kappa B; Quinoxalines; Syria; Toll-Like Receptors | 2018 |
EAPB0503, an Imidazoquinoxaline Derivative Modulates SENP3/ARF Mediated SUMOylation, and Induces NPM1c Degradation in NPM1 Mutant AML.
Topics: Animals; Cysteine Endopeptidases; Humans; Leukemia, Myeloid, Acute; Mice; Mutation; Nuclear Proteins; Nucleophosmin; Quinoxalines; Sumoylation | 2022 |