quinoxalines has been researched along with dizocilpine maleate in 456 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.22) | 18.7374 |
| 1990's | 264 (57.89) | 18.2507 |
| 2000's | 148 (32.46) | 29.6817 |
| 2010's | 41 (8.99) | 24.3611 |
| 2020's | 2 (0.44) | 2.80 |
| Authors | Studies |
|---|---|
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Kemel, ML | 1 |
| Boddeke, HW; Massieu, L; Mengod, G; Palacios, JM; Rocamora, N | 2 |
| Nellgård, B; Wieloch, T | 3 |
| Hansen, AJ; Lauritzen, M | 1 |
| Bowyer, JF; Frame, LT; Lipe, GW; Newport, GD | 1 |
| Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP; Hartley, DM; Monyer, H | 1 |
| Jönsson, T; Lehmann, A | 1 |
| Ebert, U; Koch, M | 1 |
| Dichter, MA; Molinoff, PB; Williams, K | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Birder, LA; de Groat, WC | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Argiolas, A; Melis, MR; Stancampiano, R | 1 |
| Pai, KS; Ravindranath, V | 1 |
| Baraban, JM; Blatter, LA; Murphy, TH; Wier, WG | 1 |
| Johnston, MV; McDonald, JW | 1 |
| Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 1 |
| Morán, J; Rivera-Gaxiola, M | 1 |
| Calder, LD; Karler, R | 1 |
| DeFeo, PA; Hargrove, H; Patel, J; Salama, AI; Thompson, C; Zinkand, WC | 1 |
| Castrén, E; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Lund, A; Olsen, UB | 1 |
| Crane, AM; Driscoll, BF; Law, MJ | 1 |
| Hayakawa, T; Kinoshita, A; Kohmura, E; Yamada, K | 1 |
| Bovolin, P; Costa, E; Grayson, DR; Memo, M | 1 |
| Bockaert, J; Do, E; Manzoni, OJ; Poulat, F; Sahuquet, A; Sassetti, I; Sladeczek, FA | 1 |
| Ogita, K; Yoneda, Y | 2 |
| Choi, DW; Goldberg, MP; Kaku, DA | 1 |
| Bockaert, J; Manzoni, OJ; Prezeau, L | 1 |
| Andrew, M; Farley, JM; Ho, IK; Oden, G; Rockhold, RW | 1 |
| Avoli, M; Hwa, GG | 1 |
| Gribkoff, VK | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Cuénod, M; Do, KQ; Fontana, A; Frei, K; Piani, D | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Bengzon, J; Ernfors, P; Kokaia, Z; Lindvall, O; Persson, H; Siesjö, BK; Smith, ML | 1 |
| Bengzon, J; Ernfors, P; Kokaia, Z; Lindvall, O; Persson, H | 1 |
| Florentino, A; Kunos, G; Varga, K | 1 |
| Labruyere, J; Olney, JW; Price, MT; Stewart, GR; Wang, GJ; Zorumski, CF | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Cannon-Spoor, HE; Freed, WJ | 1 |
| Miyamoto, T; Okada, Y; Sakurai, T | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Hoehn, K; White, TD | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Davidson, N; Fong, TM; Lester, HA | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Browne, SE; Bullock, R; Dawson, D; Fujisawa, H; MacKay, KB; McCulloch, J | 1 |
| Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Hamada, T; Ono, M; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| Greenamyre, JT; Greene, JG | 2 |
| Farfel, GM; Seiden, LS | 1 |
| Hoff, P; Tegtmeier, F; Xie, Y; Zacharias, E | 1 |
| Alvarado, S; Blume, H; Firkusny, I; Geary, C; Jensen, FE | 1 |
| Hanada, T; Izumisawa, N; Kawakami, A; Ohata, T; Okeda, R | 1 |
| McCulloch, J; Patel, TR | 1 |
| Cervo, L; Samanin, R | 2 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M; Verrecchia, C | 1 |
| Cho, KP; Eun, YA; Kim, DC; Kim, HI; Kim, KW; Kim, YH | 1 |
| Carraro, S; Guarnieri, T; Villani, L | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Johansson, BB; Westergren, I | 1 |
| Nordholm, L; Sheardown, MJ; Suzdak, PD | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Buchan, AM; Li, H | 1 |
| Choi, DW; Goldberg, MP; Gottlieb, DI; Huettner, JE; Turetsky, DM | 1 |
| Massieu, L; Morales-Villagrán, A; Tapia, R | 1 |
| Choi, DW; Gwag, BJ; Koh, JY; Lobner, D | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Gonzales, RA; Roper, LC | 1 |
| Barnabei, O; Contestabile, A; Virgili, M | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Barth, A; Malouf, AT; Newell, DW | 1 |
| Bedingfield, JB; Calder, LD; Karler, R; Thai, LH | 1 |
| Cui, Q; Harvey, AR | 1 |
| Starr, BS; Starr, MS | 2 |
| Andiné, P; Diemer, NH; Gilland, E; Hagberg, H | 1 |
| Folbergrová, J | 2 |
| Pai, KS; Ravindranath, V; Shankar, SK | 1 |
| Buckley, B; Lutton, LM; Rea, MA | 1 |
| López-Colomé, AM; Ortega, A; Romo-de-Vivar, M | 1 |
| Kim, K; Lee, CC; Lee, YK; Seong, JY | 1 |
| Hagberg, H; Lehmann, A; Orwar, O; Sandberg, M | 1 |
| Haddad, GG; Jiang, C | 1 |
| Hönack, D; Löscher, W; Rundfeldt, C | 1 |
| Fukunaga, K; Miyamoto, E; Ushio, Y; Yano, S | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, P; Xu, Y; Yang, GY | 1 |
| Choi, DW; Regan, RF | 1 |
| Schmidt, WJ; Zadow, B | 1 |
| Mao, J; Mayer, DJ; Price, DD | 1 |
| Puro, DG; Uchihori, Y | 1 |
| Krieglstein, J; Lippert, K; Welsch, M | 1 |
| de Groat, WC; Sugaya, K | 1 |
| Bigl, V; Kumar, A; Schliebs, R | 1 |
| Scholfield, CN; Yassin, M | 1 |
| Fung, ML; St John, WM; Wang, W | 1 |
| Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Holmberg, L; Seiger, A; Sundström, E; von Euler, M | 1 |
| Ohta, H; Talman, WT | 1 |
| Lindsay, AD; Weiss, JH; Yin, HZ | 1 |
| Dragunow, M; Young, D | 2 |
| Metsis, M; Timmusk, T | 1 |
| Hönack, D; Löscher, W | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, PR; Xu, Y | 1 |
| McEwen, BS; Woolley, CS | 1 |
| Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Anderson, JJ; Boldry, RC; Chase, TN; Engber, TM; Kuo, S; Papa, SM | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Goettl, VM; Larson, AA | 1 |
| Canella, R; Comelli, MC; Guidolin, D; Manev, H; Rubini, R; Seren, MS; Zanoni, R | 1 |
| Couratier, P; Dumas, M; Hugon, J; Sindou, P; Vallat, JM | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Giacobini, E; Matsuoka, Y; Naritoku, D; Rakonczay, Z | 1 |
| Dawson, TM; Dawson, VL; Snyder, SH; Uhl, GR | 1 |
| Janáky, R; Oja, SS; Saransaari, P | 1 |
| Greenamyre, JT | 1 |
| Black, IB; Dreyfus, CF; Mount, HT | 1 |
| Ince, PG; Johnson, M; Perry, EK; Perry, RH; Shaw, PJ | 1 |
| al-Zubaidy, ZA; Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| Court, JA; Ince, PG; Johnson, M; Kerwin, JA; Perry, EK; Perry, RH; Piggott, MA | 1 |
| Berg, M; Bruhn, T; Diemer, NH; Johansen, FF | 1 |
| Dretchen, KL; Gillis, RA; McManigle, JE; Taveira DaSilva, AM | 1 |
| Keana, JF; Lutfy, K; Weber, E; Woodward, RM | 1 |
| Lipton, P; Lobner, D | 1 |
| Hao, JX; Seiger, A; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Aoki, M; Fackler, JC; Hickey, PR; Holtzman, D; Jonas, RA; Nomura, F; Stromski, ME; Tsuji, MK | 1 |
| Cotman, CW; Pike, CJ; Weiss, JH | 1 |
| Christensen, T; Diemer, NH; Jørgensen, MB | 1 |
| Keana, JF; Kest, B; Liebeskind, JC; Marek, P; Vaccarino, AL; Weber, E | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Papa, SM | 1 |
| Cappendijk, SL; de Vries, R; Dzoljic, MR | 1 |
| Grantyn, R; Rörig, B | 1 |
| Chae, LO; Edelman, NH; Melton, JE; Neubauer, JA | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Fowler, JC | 1 |
| Chen, J; Graham, SH; Lan, JQ; Simon, RP | 1 |
| Hansen, AJ; Hillered, L; Laursen, H; Nilsson, P | 1 |
| Danysz, W; Gossel, M; Löscher, W; Schmidt, WJ; Zajaczkowski, W | 1 |
| Boireau, A; Doble, A; Meunier, M | 1 |
| Ikonomidou, C; Kirby, C; Labruyere, J; Olney, JW; Qin, Y | 1 |
| Jaw, SP; Nguyen, M; Vuong, QT | 1 |
| Balchen, T; Bruhn, T; Christensen, T; Diemer, NH; Johansen, FF; Nielsen, M; Vanicky, I | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS; Haji, A; Pierrefiche, O; Takeda, R | 1 |
| Borsini, F; Brambilla, A; Grippa, N; Prudentino, A | 1 |
| Bullock, R; Di, X | 1 |
| Mary, V; Stutzmann, JM; Wahl, F | 1 |
| Chase, TN; Qin, ZH; Wang, Y | 1 |
| Aguilar, E; Gonzalez, D; Pinilla, L; Tena-Sempere, M | 1 |
| Holmes, GL; Liu, Z; Mikati, M; Sarkisian, M; Stafstrom, CE; Tandon, P; Werner, SJ; Yang, Y | 1 |
| Cole, BJ; Stephens, DN | 1 |
| Hao, JX; Xu, XJ | 1 |
| Fedele, E; Raiteri, M | 1 |
| Lutfy, K; Shen, KZ; Weber, E; Woodward, RM | 1 |
| Hicks, C; O'Neill, MJ; Ward, M | 1 |
| Ferger, D; Krieglstein, J | 1 |
| Ben-Yoseph, O; Boxer, PA; Ross, BD | 1 |
| Hashimoto, M; Takahashi, M | 1 |
| Back, T; Fritze, K; Hossmann, KA; Vogel, P; Wiessner, C; Yamashita, K | 1 |
| Coutinho, SV; Gebhart, GF; Meller, ST | 1 |
| Coyle, JT; Getz, RL; Konradi, C; Leveque, JC; Simonian, NA | 1 |
| Brown, G; Jackson, A; Stephens, DN | 1 |
| Dalia, A; Wallace, LJ | 1 |
| Jensen, FE; Wang, C | 1 |
| Chaplan, SR; Malmberg, AB; Yaksh, TL | 1 |
| Krieglstein, J; Lippert, K; Pöch, G | 1 |
| Shiraishi, K | 1 |
| Cebers, G; Hou, YN; Liljequist, S; Terenius, L | 1 |
| Bart, RD; Pearlstein, RD; Takaoka, S; Warner, DS | 1 |
| Fusco, FR; Hirvonen, T; Hökfelt, T; Keinänen, R; Koistinaho, J; Miettinen, S; Närhi, M; Roivainen, R; Yrjänheikki, J | 1 |
| Barth, A; Malouf, AT; Newell, DW; Ricciardi, TN | 1 |
| Furukawa, K; Holtsberg, FW; Keller, JN; Mattson, MP; Steiner, MR; Steiner, SM | 1 |
| Dorandeu, F; Fosbraey, P; Lallement, G; Pernot-Marino, I; Tattersall, JE; Wetherell, J | 1 |
| Auer, RN | 1 |
| Bristow, DR; Savidge, JR | 1 |
| Berman, FW; Murray, TF | 1 |
| Dewar, D; Irving, EA; McCulloch, J; Yatsushiro, K | 1 |
| Li, HB; Matsumoto, K; Watanabe, H; Yamamoto, M | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Kalivas, PW; Meil, WM; Pierce, RC | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Waters, N; Waters, S | 1 |
| Arias, C; Arrieta, I; Massieu, L; Tapia, R | 1 |
| Danthi, SN; Hill, RA; Layer, RT; Miller, DD; Shams, G; Tai, H; Uretsky, NJ; Wallace, LJ; Weinstein, DM; Willins, D | 1 |
| Cossu, M; Fedele, E; Fontana, G; Munari, C; Raiteri, M | 1 |
| Ciani, E; Contestabile, A; Dall'Olio, R; Gandolfi, O; Sparapani, M | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Osawa, M | 1 |
| Natarajan, M; Smyth, CE; Wilkinson, M | 1 |
| Dell'Erba, G; Guarnieri, T; Villani, L | 1 |
| Grover, LM | 1 |
| Collins, MA; Corso, TD; Mostafa, HM; Neafsey, EJ | 1 |
| Hokamura, K; Kawano, K; Kawazura, H; Nakashima, M; Shimazu, Y; Umemura, K | 1 |
| Blaszczak, P; Turski, WA | 1 |
| Kuo, MF; Murphy, S; Papadopoulos, MD; Pastuszko, A; Song, D; Wilson, DF | 1 |
| Braisted, JC; Chavko, M; Harabin, AL; Outsa, NJ | 1 |
| Bartfai, T; Caltavuturo, C; Consolo, S; Uboldi, MC | 1 |
| Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G | 1 |
| Borday, V; Denavit-Saubié, M; Foutz, AS; Nordholm, L | 1 |
| Endo, T; Hara, S; Iwata, N; Kano, S; Kuriiwa, F; Mukai, T; Yanase, T | 1 |
| Bonnot, A; Morin, D; Viala, D | 1 |
| Kinzie, JM; Sahara, Y; Schoppa, NE; Segerson, TP; Westbrook, GL | 1 |
| Aguilar, E; Pinilla, L; Tena-Sempere, M | 2 |
| Begnini, J; de Bastiani, J; de Mello, CF; Fialho, DB; Jurach, A; Lima, TT; Ribeiro, MC; Wajner, M | 1 |
| Balázs, R; Facchinetti, F; Hack, NJ | 1 |
| Hashimoto, N; Iihara, K; Nishijima, T; Taniguchi, T; Tsukahara, T | 1 |
| Jensen, JB; Pickering, DS; Schousboe, A | 2 |
| Johnson, AK; Xu, Z | 1 |
| Nakamichi, T | 1 |
| Holmberg, L; Souverbie, F; Sundström, E | 1 |
| DeLorenzo, RJ; Pal, S; Sombati, S | 1 |
| Bowen, CA; Gatto, GJ; Grant, KA | 1 |
| Covey, DF; Hill, MW; Hu, Y; Yamada, KA | 1 |
| Li, H; Matsumoto, K; Watanabe, H | 1 |
| Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Yasuda, S | 1 |
| Bittigau, P; Bosch, F; Dikranian, K; Ikonomidou, C; Miksa, M; Olney, JW; Stefovska, V; Tenkova, TI; Turski, L; Vöckler, J | 1 |
| Ikeda, Y; Kondo, K; Takamatsu, H; Umemura, K | 1 |
| Faddis, BT; Goldberg, MP; Hasbani, MJ; Hyrc, KL; Romano, C | 1 |
| Fukuda, H; Furukawa, N; Hatano, M; Koga, T | 1 |
| Arias, RL; Bowlby, MR; Tasse, JR | 1 |
| Guo, Y; Regan, RF | 2 |
| Wang, YS; White, TD | 1 |
| Funato, H; Kohsaka, S; Mochizuki, H; Shimojo, M; Takasugi, K; Yamamoto, I | 1 |
| Badre, SE; Morsette, DJ; Sladek, CD; Swenson, KL | 1 |
| DeGiorgio, LA; DeGiorgio, N; Volpe, BT | 1 |
| Vanover, KE | 1 |
| Gozal, D; Simakajornboon, N; Xue, YD | 1 |
| Linden, R; Martins, RA; Rocha, M | 1 |
| Brundin, P; Schierle, GS | 1 |
| Bunney, BS; Shi, WX; Zhang, XX; Zheng, P | 1 |
| Ackley, DC; Chang, NG; Geddes, JW; McGillis, JP; Soultanian, NS; Yokel, RA | 1 |
| Gerken, U; Hossmann, K; Vogel, P; Wiessner, C; Yamashita, K | 1 |
| Cano, J; Machado, A; Merino, M; Vizuete, ML | 1 |
| Healy, DJ; Meador-Woodruff, JH | 1 |
| Allen, JW; Eldadah, BA; Faden, AI | 1 |
| Chan, PH; Hirvonen, T; Keinänen, R; Koistinaho, J; Koponen, S; Närhi, M; Roivainen, R | 1 |
| Bandtlow, CE; Gähwiler, BH; Lüthi, A; McKinney, RA; Thompson, SM | 1 |
| Geiger, JD; Haughey, NJ; Holden, CP; Nath, A | 1 |
| Kaasik, A; Kalda, A; Poldoja, E; Vassiljev, V; Zharkovsky, A | 1 |
| De Laurentiis, A; Díaz, MC; Duvilanski, B; Lasaga, M; Pampillo, M; Pisera, D; Seilicovich, A | 1 |
| Balchen, T; Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Cozzi, A; Leonardi, P; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F | 1 |
| Bailey, CJ; Li, N; Smith, ME; Young, MM | 1 |
| Chan, PH; Chen, SF; Copin, JC; Gobbel, GT; Kawase, M; Kim, GW; Sato, S | 1 |
| Bebbington, D; Benwell, KR; Lamb, H; Malcolm, CS; Porter, RH | 1 |
| Calton, JL; Kang, MH; Moore, SD; Wilson, WA | 1 |
| Folbergrová, J; Haugvicová, R; Mares, P | 1 |
| Balster, RL; Beardsley, PM; Bespalov, AY; Dravolina, OA; Zvartau, EE | 1 |
| Kohda, K; Wang, Y; Yuzaki, M | 1 |
| Li, S; Tator, CH | 1 |
| Artemenko, DP; Gerasimov, VD; Krishtal, OA | 1 |
| Gonzalez, M; Infante, C; Motles, E | 1 |
| Kapousta-Bruneau, NV | 1 |
| Gottmann, K; Hatt, H; Mohrmann, R | 1 |
| Aguilar-Veiga, E; Galán-Valiente, J; Sierra-Marcuño, G; Sierra-Paredes, G; Vazquez-Illanes, MD | 1 |
| Dacanal, J; de Mello, CF; de Souza, DO; Emanuelli, T; Prauchner, CA; Reis, EC; Zeni, A | 1 |
| Carter, AG; Regehr, WG | 1 |
| Berchanski, A; Elazar, Z | 1 |
| Bogaert, L; Bond, A; Ebinger, G; Hicks, CA; Lodge, D; Michotte, Y; O'Neill, MJ; Ornstein, PL; Ward, MA | 1 |
| Nanka, O | 1 |
| Bountra, C; Grundy, D; Kozlowski, CM | 1 |
| Breder, J; Opitz, T; Reymann, KG; Sabelhaus, CF; Schröder, UH | 1 |
| Bauer, J; Blauth, E; Darstein, M; Feuerstein, TJ; Freiman, TM; Hummel, A; Jehle, T | 1 |
| Barrachina, MD; Esplugues, JV; García-Zaragozá, E; Moreno, L | 1 |
| Brennan, TJ; Pogatzki, EM; Zahn, PK | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Morinobu, S; Yasuda, S | 1 |
| Closier, M; Iop, F; Lestage, P; Lockhart, B | 1 |
| Alfonso, M; Durán, R; Quintela, BA | 1 |
| Aguilar, E; González, LC; Pinilla, L; Tena-Sempere, M | 2 |
| Burton, FH; Campbell, KM; McGrath, MJ; Parks, CR | 1 |
| Ikonomidou, C; Stefovska, V; Turski, L | 1 |
| Daval, JL; Grojean, S; Koziel, V; Vert, P | 1 |
| Dreyer, EB; Naskar, R; Schuettauf, F; Vorwerk, CK; Zurakowski, D | 1 |
| Hashim, A; Lajtha, A; Sershen, H | 1 |
| Barat, A; Burgos, JS; Ramirez, G | 1 |
| Bernabeu, R; Sharp, FR | 1 |
| Gu, Z; Jiang, Q; Jing, G; Zhang, G | 1 |
| de Mello, FG; Ferreira, ST; Louzada, PR; Paula Lima, AC | 1 |
| Bardoul, M; Drian, MJ; König, N | 1 |
| Blaabjerg, M; Bonde, C; Kristensen, BW; Zimmer, J | 1 |
| Cheng, JS; Ren, JP; Xia, HL | 1 |
| Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J | 1 |
| Asai, K; Fujita, K; Katano, H; Kato, T; Kawamura, Y; Masago, A; Yamada, K | 1 |
| Lampson, LA; McCluskey, LP | 1 |
| Canonico, PL; Dianzani, C; Fantozzi, R; Lombardi, G; Miglio, G | 1 |
| Andersson, K; Chen, Y; Dell'Anna, E; Engidawork, E; Goiny, M; Gross, J; Herrera-Marschitz, M; Kohlhauser, C; Loidl, F; Lubec, B; Lubec, G; Stoeckler, S | 1 |
| Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
| Emch, GS; Hermann, GE; Rogers, RC | 1 |
| Fukuda, H; Furukawa, N; Hatano, M | 1 |
| Beirith, A; Calixto, JB; Santos, AR | 1 |
| Bedi, KS; Bellinger, FP; Wilce, PA; Wilson, P | 1 |
| Dikranian, K; Farber, NB; Heinkel, C; Jiang, XP; Kim, SH | 1 |
| Attwell, D; Hamann, M; Marie, H; Rossi, DJ | 1 |
| Fonnum, F; Mariussen, E; Myhre, O; Reistad, T | 1 |
| Albrecht, J; Borkowska, HD; Goryński, P; Hilgier, W; Oja, SS; Saransaari, P; Zielińska, M | 1 |
| Chen, H; Rossi, NF | 1 |
| Azbill, RD; Mu, X; Springer, JE | 1 |
| Acerbo, MJ; Delius, JD; Gargiulo, PA; Krug, I | 1 |
| Bazan, NG; de Turco, EB; Diemer, NH; Kolko, M | 1 |
| Stein, EA; Xi, ZX | 1 |
| Burr, PB; Morris, BJ | 1 |
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Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y | 1 |
| Balu, DT; Coyle, JT; Takagi, S | 1 |
3 review(s) available for quinoxalines and dizocilpine maleate
| Article | Year |
|---|---|
Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haplorhini; Humans; Mice; MPTP Poisoning; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Quinoxalines; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus.
Topics: Age Factors; Animals; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Electrophysiology; Epilepsy, Temporal Lobe; Hippocampus; Hypoxia; In Vitro Techniques; Lorazepam; Quinoxalines; Rats | 1996 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
1 trial(s) available for quinoxalines and dizocilpine maleate
453 other study(ies) available for quinoxalines and dizocilpine maleate
| Article | Year |
|---|---|
Modulation of GABA release by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and N-methyl-D-aspartate receptors in matrix-enriched areas of the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Histocytochemistry; Ibotenic Acid; Male; Nerve Endings; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptosomes; Tetrodotoxin; Veratridine | 1992 |
Administration of quinolinic acid in the rat hippocampus induces expression of c-fos and NGFI-A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Hippocampus; Ibotenic Acid; In Situ Hybridization; Injections, Intraperitoneal; Male; Oligonucleotide Probes; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cell Membrane Permeability; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Cortex; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Glucose; Blood Pressure; Body Temperature; Cell Death; Dizocilpine Maleate; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
A further evaluation of the effects of K+ depolarization on glutamate-evoked [3H]dopamine release from striatal slices.
Topics: Animals; Corpus Striatum; Culture Techniques; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Kynurenic Acid; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophysiology; Glucose; Glutamates; Glutamic Acid; Magnesium; Mice; Neurons; Neurotransmitter Agents; Oxygen; Potassium; Quinoxalines; Tetanus Toxin | 1992 |
MK-801 selectively protects mouse arcuate neurons in vivo against glutamate toxicity.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Neurons; Quinoxalines | 1992 |
Glutamate receptors mediate acoustic input to the reticular brain stem.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Dizocilpine Maleate; Evoked Potentials, Auditory, Brain Stem; Female; Glutamates; Iontophoresis; Pons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Reticular Formation | 1992 |
Up-regulation of N-methyl-D-aspartate receptors on cultured cortical neurons after exposure to antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1992 |
NMDA receptors, cellular edema, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Dizocilpine Maleate; Edema; Electron Transport; Glycolysis; Hypoglycemia; Hypoxia; Iodoacetates; Iodoacetic Acid; Ischemia; N-Methylaspartate; Potassium Cyanide; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Tetrodotoxin | 1992 |
The effect of glutamate antagonists on c-fos expression induced in spinal neurons by irritation of the lower urinary tract.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Decerebrate State; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, fos; Glutamates; Glutamic Acid; Irritants; Neurons; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Spinal Cord; Urinary Tract | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. III. Changes in the NMDA receptor complex induced by their functional cooperation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1992 |
AMPA and NMDA receptor antagonists do not decrease hippocampal glutamate concentrations during transient global ischemia.
Topics: Animals; Aspartic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reperfusion | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Effect of excitatory amino acid receptor antagonists on apomorphine-, oxytocin- and ACTH-induced penile erection and yawning in male rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenocorticotropic Hormone; Aminobutyrates; Animals; Apomorphine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Oxytocin; Penile Erection; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Yawning | 1992 |
Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Mice; Potassium; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1992 |
Spontaneous synchronous synaptic calcium transients in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophysiology; Fetus; Fluorescent Dyes; Kainic Acid; Kinetics; Membrane Potentials; Microscopy, Fluorescence; Neurons; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Time Factors | 1992 |
Neuroprotective synergism of 2-amino-3-phosphonoproprionate (D,L-AP3) and MK-801 against ibotenate induced brain injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Female; Ibotenic Acid; Injections; Male; Organ Size; Quinoxalines; Rats; Rats, Sprague-Dawley | 1992 |
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Pain; Peripheral Nervous System Diseases; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve | 1992 |
Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Cell Death; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Insulin Coma; Male; Necrosis; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Effect of potassium and N-methyl-D-aspartate on the aspartate aminotransferase activity in cultured cerebellar granule cells.
Topics: Analysis of Variance; Animals; Aspartate Aminotransferases; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Kinetics; Magnesium; N-Methylaspartate; Neurons; Nifedipine; Potassium; Quinoxalines; Rats; Tetrodotoxin | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Quisqualate neurotoxicity in rat cortical cultures: pharmacology and mechanisms.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diazepam; Dizocilpine Maleate; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kinetics; Male; Nerve Growth Factors; Nerve Tissue Proteins; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; RNA, Messenger; Tetrodotoxin | 1991 |
Inhibition by glutamate antagonists, MK-801 and NBQX, of cutaneo-cardiovascular pain reflex in rats.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dizocilpine Maleate; Female; Heart Rate; Pain; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Reflex; Skin; Skin Physiological Phenomena | 1991 |
Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Buffers; Cells, Cultured; Culture Media; Dizocilpine Maleate; Glutamates; Glutamic Acid; Mesencephalon; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
Neurotoxicity caused by glutamate after subcritical hypoxia is prevented by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX): an in vitro study using rat hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Nervous System Diseases; Neurons; Pregnancy; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Regulation of gamma-aminobutyric acidA receptor subunit expression by activation of N-methyl-D-aspartate-selective glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamates; Glutamic Acid; Molecular Sequence Data; Muscimol; N-Methylaspartate; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger | 1991 |
Pharmacological characterization of the quisqualate receptor coupled to phospholipase C (Qp) in striatal neurons.
Topics: 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Cells, Cultured; Corpus Striatum; Dizocilpine Maleate; Fura-2; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Phorbol 12,13-Dibutyrate; Phosphoserine; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Type C Phospholipases | 1991 |
Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.
Topics: Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Drug Synergism; Glutamates; Glutamic Acid; Glycine; Ligands; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Culture Media; Dizocilpine Maleate; Fetus; Glucose; Kynurenic Acid; Mice; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
beta-N-methylamino-L-alanine is a low-affinity agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Diamino; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyanobacteria Toxins; Cycloleucine; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Inositol; Inositol Phosphates; Kinetics; Mice; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Glutamate receptor antagonists block cocaine-induced convulsions and death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Time Factors | 1991 |
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Electrophysiological evidence for N-methyl-D-aspartate excitatory amino acid receptors in the rat supraoptic nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Electrophysiology; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Synaptic Transmission | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Dizocilpine Maleate; Glutamates; Glutamic Acid; Macrophages; Mice; Mice, Inbred ICR; Neuroglia; Neurons; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Gene Expression; Hippocampus; Insulin Coma; Ischemic Attack, Transient; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Nucleic Acid Hybridization; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors | 1992 |
Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Epilepsy; Kindling, Neurologic; Male; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1991 |
Mechanism of the cardiovascular effects of GABAB receptor activation in the nucleus tractus solitarii of the rat.
Topics: Anesthesia; Animals; Baclofen; Blood Pressure; Dizocilpine Maleate; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; Pertussis Toxin; Pressoreceptors; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Urethane; Virulence Factors, Bordetella | 1990 |
6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor complex.
Topics: Animals; Binding Sites; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Resistance; Glutamates; Glutamic Acid; Glycine; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Synaptic Membranes; Tritium | 1990 |
Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chick Embryo; Dibenzocycloheptenes; Dihydroxyphenylalanine; Dizocilpine Maleate; Hippocampus; Huntington Disease; Levodopa; Neurons; Parkinson Disease; Quinoxalines; Receptors, Neurotransmitter; Retina | 1990 |
Stimulation of dopamine release from cultured rat mesencephalic cells by naturally occurring excitatory amino acids: involvement of both N-methyl-D-aspartate (NMDA) and non-NMDA receptor subtypes.
Topics: Amino Acids; Animals; Calcium; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Kainic Acid; Mesencephalon; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical | 1990 |
A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glutamates; Mice; Motor Activity; Phencyclidine; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Stereotyped Behavior | 1990 |
Masking effect of NMDA receptor antagonists on the formation of long-term potentiation (LTP) in superior colliculus slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Magnesium; Mice; Nerve Degeneration; Optic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Visual Cortex | 1990 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Animals; Calcium; Cerebral Cortex; Dipeptides; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Further evidence demonstrating that N-methyl-D-aspartate and kainate activate distinct ion channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ion Channels; Membrane Potentials; Oocytes; Quinoxalines; Rats; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1989 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Pharmacological modification of glutamate neurotoxicity in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzofurans; Blood Pressure; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Male; Microdialysis; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrimidines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar | 1993 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
N-methyl-D-aspartate induces phase shifts in circadian rhythm of neuronal activity of rat SCN in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dizocilpine Maleate; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Neurons; Neuropeptide Y; Quinoxalines; Rats; Rats, Wistar; Suprachiasmatic Nucleus | 1994 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; Cell Death; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Isoquinolines; Male; Malonates; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX.
Topics: Animals; Body Temperature; Brain Chemistry; Dizocilpine Maleate; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin | 1995 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburide; Heart Arrest; Hypoxia; Ion Channels; Male; Nimodipine; Piperidines; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Sodium; Thiazoles | 1995 |
NBQX blocks acute and late epileptogenic effects of perinatal hypoxia.
Topics: Age Factors; Animals; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Flurothyl; Hypoxia, Brain; Lorazepam; Male; Quinoxalines; Rats; Receptors, AMPA | 1995 |
YM90K, an AMPA antagonist, has no neurotoxic effects on cerebrocortical neurons in rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Dizocilpine Maleate; Female; Gyrus Cinguli; Immunohistochemistry; Microscopy, Electron; Quinoxalines; Rats; Rats, Inbred F344; Receptors, AMPA | 1995 |
AMPA receptor antagonism attenuates MK-801-induced hypermetabolism in the posterior cingulate cortex.
Topics: Animals; Autoradiography; Behavior, Animal; Deoxyglucose; Dizocilpine Maleate; Gyrus Cinguli; Limbic System; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stereotyped Behavior; Tissue Distribution | 1995 |
Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulpiride | 1995 |
Blockers of NMDA-operated channels decrease glutamate and aspartate extracellular accumulation in striatum during forebrain ischaemia in rats.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Corpus Striatum; Dizocilpine Maleate; Glutamic Acid; Magnesium; Male; Microdialysis; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Ca2+-dependent and -independent mechanisms of ischaemia-evoked release of [3H]-dopamine from rat striatal slices.
Topics: Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Corpus Striatum; Culture Techniques; Cyclopentanes; Dantrolene; Dizocilpine Maleate; Dopamine; Ketamine; Magnesium Sulfate; Nomifensine; omega-Conotoxin GVIA; Peptides; Quinoxalines; Rats; Tetrodotoxin; Verapamil | 1995 |
6,7-Dinitroquinoxaline-2,3-dione but not MK-801 exerts a protective effect against kainic acid neurotoxicity in the goldfish retina.
Topics: Animals; Choline O-Acetyltransferase; Dizocilpine Maleate; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Goldfish; Immunohistochemistry; Kainic Acid; Microscopy, Electron; Neuroprotective Agents; Neurotoxins; Quinoxalines; Retina | 1995 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Blockade of AMPA receptors reduces brain edema following opening of the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Dizocilpine Maleate; Evans Blue; Excitatory Amino Acid Antagonists; Injections, Intravenous; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Specific Gravity; Staining and Labeling | 1993 |
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gerbillinae; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kinetics; Male; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Diseases; Dizocilpine Maleate; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Prosencephalon; Quinoxalines; Rats; Rats, Wistar | 1993 |
Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Carcinoma, Embryonal; Cell Differentiation; Dizocilpine Maleate; Electrophysiology; Female; Immunohistochemistry; Indicators and Reagents; Ion Channels; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Pregnancy; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tretinoin; Tumor Cells, Cultured | 1993 |
Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study.
Topics: Animals; Cell Death; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar | 1995 |
Potentiated necrosis of cultured cortical neurons by neurotrophins.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Mice; N-Methylaspartate; Necrosis; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotrophin 3; Quinoxalines; Receptors, AMPA | 1995 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Ethanol effects of NMDA-stimulated levels of extracellular neurotransmitters by in vivo microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Simultaneous blockade of non-NMDA ionotropic receptors and NMDA receptor-associated ionophore partially protects hippocampal slices from protein synthesis impairment due to simulated ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; In Vitro Techniques; Ionophores; Leucine; Male; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Immunohistochemistry; Injections; Male; Neostriatum; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1995 |
Glycine site NMDA receptor antagonists provide protection against ischemia-induced neuronal damage in hippocampal slice cultures.
Topics: Animals; Brain Ischemia; Cell Death; Dizocilpine Maleate; Glycine; Glycine Agents; Hippocampus; Kynurenic Acid; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
A dopaminergic-glutamatergic basis for the action of amphetamine and cocaine.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Male; Mice; Piperazines; Quinoxalines; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Sulpiride | 1994 |
NT-4/5 reduces naturally occurring retinal ganglion cell death in neonatal rats.
Topics: Amidines; Animals; Animals, Newborn; Cell Death; Cycloheximide; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Nerve Growth Factors; Quinoxalines; Rats; Rats, Wistar; Retinal Ganglion Cells | 1994 |
Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Male; Microinjections; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; RNA, Messenger | 1994 |
Comparison of the effects of NMDA and AMPA antagonists on the locomotor activity induced by selective D1 and D2 dopamine agonists in reserpine-treated mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenethylamines; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine | 1994 |
Hypoxia-ischemia in the neonatal rat brain: histopathology after post-treatment with NMDA and non-NMDA receptor antagonists.
Topics: Animals; Animals, Newborn; Brain Damage, Chronic; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Hypoxia, Brain; Injections, Intraperitoneal; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Severity of Illness Index; Treatment Outcome | 1994 |
NMDA and not non-NMDA receptor antagonists are protective against seizures induced by homocysteine in neonatal rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Dizocilpine Maleate; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Billion-fold difference in the toxic potencies of two excitatory plant amino acids, L-BOAA and L-BMAA: biochemical and morphological studies using mouse brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Diamino; Animals; beta-Alanine; Brain; Brain Chemistry; Cyanobacteria Toxins; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Histocytochemistry; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Neurotoxins; Paraffin Embedding; Plants; Potassium; Quinoxalines | 1993 |
Local administration of EAA antagonists blocks light-induced phase shifts and c-fos expression in hamster SCN.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Activity Cycles; Animals; Circadian Rhythm; Cricetinae; Dizocilpine Maleate; Gene Expression; Genes, fos; Light; Male; Mesocricetus; Microinjections; Motor Activity; Proto-Oncogene Proteins c-fos; Quinoxalines; Stereotaxic Techniques; Suprachiasmatic Nucleus | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
NMDA receptor antagonist decreases the progesterone-induced increase in GnRH gene expression in the rat hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Estrogens; Female; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Ovariectomy; Ovary; Progesterone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Cysteine sulphinate and cysteate: mediators of cysteine toxicity in the neonatal rat brain?
Topics: Amino Acids; Animals; Animals, Newborn; Brain; Cerebral Cortex; Cysteic Acid; Cysteine; Dizocilpine Maleate; Female; Male; Nerve Degeneration; Neurons; Neurotoxins; Neurotransmitter Agents; Organ Specificity; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Brain Stem; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Microelectrodes; Neurons; Neurotransmitter Agents; Quinoxalines; Rats; Sodium | 1993 |
Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epilepsies, Partial; Female; Kindling, Neurologic; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1993 |
Activation of Ca2+/calmodulin-dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Animals, Newborn; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Immunoblotting; Ionomycin; Molecular Weight; Phosphoproteins; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Vimentin | 1994 |
Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cerebral Cortex; Dizocilpine Maleate; Energy Metabolism; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; Kynurenic Acid; Neurotoxins; Phosphocreatine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; L-Lactate Dehydrogenase; Mice; Neuroglia; Neurons; Nimodipine; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Trypan Blue | 1994 |
The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Drug Interactions; Ergolines; Haloperidol; Levodopa; Male; Pilot Projects; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; G(M1) Ganglioside; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Morphine; Pain; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Middle Aged; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction | 1993 |
Over-additive protective effect of dizocilpine and NBQX against neuronal damage.
Topics: Animals; Brain Ischemia; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Mice; Neurons; Quinoxalines; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, AMPA | 1994 |
Effects of MK-801 and CNQX, glutamate receptor antagonists, on bladder activity in neonatal rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neural Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Urinary Bladder | 1994 |
Postnatal development of NMDA, AMPA, and kainate receptors in individual layers of rat visual cortex and the effect of monocular deprivation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Autoradiography; Dizocilpine Maleate; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Vision, Monocular; Visual Cortex | 1994 |
NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Dizocilpine Maleate; Evoked Potentials; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Involvement of pontile NMDA receptors in inspiratory termination in rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Male; Pons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiration | 1994 |
Glutamate agonists and [3H]GABA release from rat hippocampal slices: involvement of metabotropic glutamate receptors in the quisqualate-evoked release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
NBQX, a competitive non-NMDA receptor antagonist, reduces degeneration due to focal spinal cord ischemia.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ischemia; Lasers; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; Spinal Cord; Time Factors | 1994 |
Both NMDA and non-NMDA receptors in the NTS participate in the baroreceptor reflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baroreflex; Blood Pressure; Dizocilpine Maleate; Drug Interactions; Functional Laterality; Heart Rate; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1994 |
Kainate injury to cultured basal forebrain cholinergic neurons is Ca2+ dependent.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Choline O-Acetyltransferase; Cobalt; Dizocilpine Maleate; Fetus; Immunohistochemistry; Kainic Acid; Kinetics; Mice; Neurons; Neurotoxins; Prosencephalon; Quinoxalines; Receptors, AMPA; Time Factors | 1994 |
MK-801 and NBQX prevent electrically induced status epilepticus.
Topics: Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Electric Stimulation; Hippocampus; Injections, Intraperitoneal; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine; Status Epilepticus | 1994 |
Regulation of BDNF promoters in the rat hippocampus.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Exons; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Ribonucleases; RNA, Messenger | 1994 |
Over-additive anticonvulsant effect of memantine and NBQX in kindled rats.
Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Drug Synergism; Female; Kindling, Neurologic; Memantine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 1994 |
Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate.
Topics: Animals; Brain Edema; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Energy Metabolism; Glutamic Acid; Kynurenic Acid; Magnetic Resonance Spectroscopy; Organ Size; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Sodium Channels | 1994 |
Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Dizocilpine Maleate; Estradiol; Female; Hippocampus; Ovariectomy; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1994 |
Combined blockade of NMDA and non-NMDA receptors produces respiratory arrest in the adult cat.
Topics: Animals; Cats; Dizocilpine Maleate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Respiration Disorders | 1994 |
Excitatory amino acid receptor antagonists modify regional cerebral metabolic responses to levodopa in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Organ Specificity; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
NMDA and non-NMDA receptors may play distinct roles in timing mechanisms and transmission in the feline respiratory network.
Topics: Action Potentials; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Carbon Dioxide; Cats; Dizocilpine Maleate; N-Methylaspartate; Neurons; Phrenic Nerve; Pulmonary Alveoli; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Synaptic Transmission; Time Factors | 1994 |
Antinociception induced by 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid (CPP), an N-methyl-D-aspartate (NMDA) competitive antagonist, plus 6,7-dinitroquinoxaline-2,3-dione (DNQX), a non-NMDA antagonist, differs from that induced by MK-801 pl
Topics: Animals; Dizocilpine Maleate; Formaldehyde; Injections, Spinal; Male; Mice; Pain; Pain Measurement; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1994 |
Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebrovascular Disorders; Dizocilpine Maleate; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression; Genes, fos; Genes, jun; Immediate-Early Proteins; In Situ Hybridization; Kinetics; Male; Membrane Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Photochemistry; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Ciliary Neurotrophic Factor; RNA, Messenger; Rose Bengal; Time Factors; Transcription Factors | 1993 |
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
L-beta-methylamino-alanine-induced behavioral changes in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids, Diamino; Animals; Behavior, Animal; Cyanobacteria Toxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.
Topics: Animals; Arginine; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamates; Glutamic Acid; Hemoglobins; HIV Envelope Protein gp120; HIV-1; Inositol Phosphates; Models, Neurological; Neurons; Neurotoxins; Nifedipine; Nitric Oxide; Nitroarginine; Quinoxalines; Rats | 1993 |
Release of GABA from rat hippocampal slices: involvement of quisqualate/N-methyl-D-aspartate-gated ionophores and extracellular magnesium.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Purkinje cell survival is differentially regulated by metabotropic and ionotropic excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Cell Survival; Cells, Cultured; Cyclopentanes; Dizocilpine Maleate; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Autoradiographic comparison of the distribution of [3H]MK801 and [3H]CNQX in the human cerebellum during development and aging.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aging; Autoradiography; Cerebellum; Child; Child, Preschool; Dizocilpine Maleate; Embryonic and Fetal Development; Fetus; Humans; Infant; Infant, Newborn; Middle Aged; Quinoxalines; Tissue Distribution; Tritium | 1993 |
Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Female; Lamotrigine; Male; Motor Activity; Phenytoin; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Triazines | 1993 |
Regional patterns of cholinergic and glutamate activity in the developing and aging human brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Brain; Child; Child, Preschool; Choline O-Acetyltransferase; Dizocilpine Maleate; Embryonic and Fetal Development; Humans; Infant; Infant, Newborn; Middle Aged; Quinoxalines; Receptors, AMPA; Receptors, Glutamate | 1993 |
Kainic acid-induced seizures and brain damage in the rat: different effects of NMDA- and AMPA receptor antagonists.
Topics: Animals; Behavior, Animal; Brain; Dizocilpine Maleate; Drug Synergism; Kainic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Rate | 1993 |
Potentiation of MK-801-induced breathing impairment by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: Animals; Blood Pressure; Cats; Dizocilpine Maleate; Female; Heart Rate; Injections, Intravenous; Male; Phrenic Nerve; Quinoxalines; Receptors, AMPA; Respiration; Respiratory Function Tests | 1994 |
Inhibition of clonic seizure-like excitatory effects induced by intrathecal morphine using two NMDA receptor antagonists: MK-801 and ACEA-1011.
Topics: Analgesics; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; In Vitro Techniques; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Morphine; Motor Activity; Oocytes; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Seizures; Xenopus laevis | 1994 |
Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: relationship to electrophysiological cell damage.
Topics: Amiloride; Animals; Calcium; Dizocilpine Maleate; Ethers, Cyclic; Guanidines; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Kinetics; Male; Microscopy, Electron; Okadaic Acid; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Systemic excitatory amino acid receptor antagonists of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and of the N-methyl-D-aspartate (NMDA) receptor relieve mechanical hypersensitivity after transient spinal cord ischemia in
Topics: Animals; Dizocilpine Maleate; Female; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Skin Physiological Phenomena; Spinal Cord; Vocalization, Animal | 1993 |
Effects of MK-801 and NBQX on acute recovery of piglet cerebral metabolism after hypothermic circulatory arrest.
Topics: Animals; Brain; Cerebrovascular Circulation; Dizocilpine Maleate; Energy Metabolism; Glucose; Heart Arrest, Induced; Hydrogen-Ion Concentration; Intracellular Membranes; Lactates; Lactic Acid; Oxygen; Phosphates; Quinoxalines; Swine; Swine, Miniature | 1994 |
Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.
Topics: Amyloid beta-Peptides; Animals; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Mice; Neurons; Neurotoxins; Nimodipine; Quinoxalines | 1994 |
Non-NMDA glutamate receptors are involved in the maintenance of status epilepticus.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cerebral Ventricles; Dizocilpine Maleate; Electric Stimulation; Electroencephalography; Hippocampus; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Muscarinic; Scopolamine; Status Epilepticus | 1993 |
Impairment of Fos protein formation in the rat infarct borderzone by MK-801, but not by NBQX.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Cortical Spreading Depression; Dizocilpine Maleate; Energy Metabolism; Gene Expression Regulation; Male; Neurons; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate | 1993 |
NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin.
Topics: Analgesics; Animals; Behavior, Animal; Dizocilpine Maleate; Foot; Formaldehyde; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Pain; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1993 |
Opposite effects of NMDA and AMPA receptor blockade on catalepsy induced by dopamine receptor antagonists.
Topics: Animals; Benzazepines; Catalepsy; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Quinoxalines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Salicylamides | 1993 |
Excitatory amino acid receptor antagonists and naloxone-precipitated withdrawal syndrome in morphine-dependent mice.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Mice; Morphine Dependence; Naloxone; Quinoxalines; Receptors, Amino Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substance Withdrawal Syndrome | 1993 |
Rat retinal ganglion cells express Ca(2+)-permeable non-NMDA glutamate receptors during the period of histogenetic cell death.
Topics: Amino Acids; Animals; Cadmium; Calcium; Cell Death; Dizocilpine Maleate; In Vitro Techniques; Permeability; Quinoxalines; Rats; Receptors, Glutamate; Retinal Ganglion Cells | 1993 |
Phrenic and sympathetic nerve responses to glutamergic blockade during normoxia and hypoxia.
Topics: Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Hypercapnia; Hypoxia; Male; Phrenic Nerve; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 1993 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
Choline substitution for sodium triggers glutamate and adenosine release from rat hippocampal slices.
Topics: Adenosine; Animals; Choline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium | 1995 |
A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1996 |
Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels.
Topics: Animals; Autoradiography; Brain Injuries; Calcium; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ion Channels; Male; Necrosis; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1996 |
Effect of coadministration of glutamate receptor antagonists and dopaminergic agonists on locomotion in monoamine-depleted rats.
Topics: Animals; Biogenic Monoamines; Bromocriptine; Dizocilpine Maleate; Dopamine Agonists; Drug Combinations; Excitatory Amino Acid Antagonists; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 1995 |
3-Nitropropionic acid exacerbates [3H]GABA release evoked by glucose deprivation in rat striatal slices.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Hypoglycemia; Isotope Labeling; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Sodium Channels; Tritium | 1996 |
Prevention of trauma-induced neurodegeneration in infant rat brain.
Topics: Animals; Brain Injuries; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Wounds and Injuries | 1996 |
Effects of glutamate receptor antagonists on posthypoxic myoclonus in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypoxia, Brain; Male; Myoclonus; Quinoxalines; Rats; Rats, Sprague-Dawley | 1996 |
Extended studies on the effect of glutamate antagonists on ischemic CA-1 damage.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Neurons; Premedication; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Pharmacological properties of peripherally induced postsynaptic potentials in bulbar respiratory neurons of decerebrate cats.
Topics: Animals; Bicuculline; Cats; Decerebrate State; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Glycine Agents; Membrane Potentials; Motor Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiratory Muscles; Spinal Nerves; Strychnine | 1996 |
Pharmacological characterization of AMPA-induced biting behaviour in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Effect of the novel high-affinity glycine-site N-methyl-D-aspartate antagonist ACEA-1021 on 125I-MK-801 binding after subdural hematoma in the rat: an in vivo autoradiographic study.
Topics: Animals; Autoradiography; Brain; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hematoma, Subdural; Humans; Male; Quinoxalines; Rats; Rats, Sprague-Dawley | 1996 |
Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission.
Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Male; Neurons; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Riluzole; Synaptic Transmission; Thiazoles; Triazines | 1995 |
Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain.
Topics: Animals; Apoptosis; Autoradiography; Deoxyuracil Nucleotides; Dizocilpine Maleate; DNA Fragmentation; DNA Nucleotidylexotransferase; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Techniques; Male; Nucleic Acid Hybridization; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1996 |
Positive role of non-N-methyl-D-aspartate receptors in the control of growth hormone secretion in male rats.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Antagonists; Growth Hormone; Kainic Acid; Male; Orchiectomy; Pituitary Gland, Anterior; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain.
Topics: Animals; Animals, Newborn; Brain; Dizocilpine Maleate; Evaluation Studies as Topic; Excitatory Amino Acid Antagonists; Exploratory Behavior; Infusion Pumps, Implantable; Injections, Intraperitoneal; Male; Maze Learning; Neuroprotective Agents; Pilot Projects; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 1996 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists.
Topics: Animals; Behavior, Animal; Chronic Disease; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hyperalgesia; Ischemia; Motor Activity; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries | 1996 |
Desensitization of AMPA receptors and AMPA-NMDA receptor interaction: an in vivo cyclic GMP microdialysis study in rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Effects of dopaminergic and glutamatergic receptor antagonists on the establishment and expression of conditioned locomotion to cocaine in rats.
Topics: Analysis of Variance; Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Locomotion; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recurrence; Substance-Related Disorders; Sulpiride | 1996 |
Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test.
Topics: Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Formaldehyde; Gene Expression; Locomotion; Male; Mice; Morphine; Motor Activity; Narcotics; Nociceptors; Oocytes; Quinoxalines; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1996 |
Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Gerbillinae; Indazoles; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Quinoxalines | 1996 |
Determination of intracellular Ca2+ concentration can be a useful tool to predict neuronal damage and neuroprotective properties of drugs.
Topics: Amantadine; Analysis of Variance; Animals; Biomarkers; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kinetics; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Cyanide; Telencephalon; Time Factors | 1996 |
Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Isotopes; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Deferoxamine; Deuterium; Dizocilpine Maleate; Fetus; Gas Chromatography-Mass Spectrometry; Glucose; Hydrogen Peroxide; Iron; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Pentose Phosphate Pathway; Putamen; Quinoxalines; Rats | 1996 |
Lowering extracellular Na+ concentration causes NMDA receptor-mediated neuronal death in cultured rat hippocampal slices.
Topics: Animals; Animals, Newborn; Calcium; Cell Death; Chlorides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neurons; Neurotoxins; Organ Culture Techniques; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1996 |
Monitoring the temporal and spatial activation pattern of astrocytes in focal cerebral ischemia using in situ hybridization to GFAP mRNA: comparison with sgp-2 and hsp70 mRNA and the effect of glutamate receptor antagonists.
Topics: Animals; Astrocytes; Brain Ischemia; Clusterin; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycoproteins; HSP70 Heat-Shock Proteins; In Situ Hybridization; Male; Molecular Chaperones; Quinoxalines; Rats; Rats, Inbred F344; RNA, Messenger; Time Factors | 1996 |
Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors.
Topics: Animals; Colon; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Zymosan | 1996 |
Kainic acid induces apoptosis in neurons.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Methionine; Nerve Tissue Proteins; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4- isoxazoleproprionate (AMPA) glutamate-receptor antagonists have different interactions with the discriminative stimuli of abused drugs.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Conditioning, Operant; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Morphine; Narcotic Antagonists; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1996 |
Amphetamine induction of c-fos in the nucleus accumbens is not inhibited by glutamate antagonists.
Topics: Amphetamines; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Nucleus Accumbens; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley | 1995 |
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch | 1997 |
Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage.
Topics: Animals; Cells, Cultured; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Memantine; Neurons; Neurotoxins; Nimodipine; Quinoxalines; Rats; Rats, Inbred F344 | 1996 |
A new non-NMDA antagonist modifies the local cerebral glucose utilization in kainate-induced generalized seizure.
Topics: Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures | 1997 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
Glycine antagonism does not block ischemic spontaneous depolarization in the rat.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ischemic Attack, Transient; Male; Membrane Potentials; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Glycine | 1997 |
Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Cortical Spreading Depression; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dizocilpine Maleate; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Functional Laterality; Hippocampus; Immunohistochemistry; In Situ Hybridization; Ischemic Attack, Transient; Isoenzymes; Male; Membrane Proteins; Neurons; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcription, Genetic | 1997 |
Glycine causes increased excitability and neurotoxicity by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoxazines; Cell Death; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Neurotoxins; Organ Culture Techniques; Oxazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Ion Channel Gating; Lysophospholipids; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Glutamate; Valine | 1997 |
Effects of excitatory amino acid antagonists on dendrotoxin-induced increases in neurotransmitter release and epileptiform bursting in rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Dizocilpine Maleate; Elapid Venoms; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neurotoxins; Neurotransmitter Agents; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Structural neurotoxicologic investigation of the glycine antagonist 5-nitro-6,7-dichloroquinoxalinedione (ACEA-1021).
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gyrus Cinguli; Male; Microscopy, Electron; Neurotoxins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glycine; Survival Rate | 1997 |
Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Distribution of Ca(2+)-permeable AMPA receptors among cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cells, Cultured; Cerebellum; Culture Media; Culture Media, Serum-Free; Diuretics; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Manganese; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1997 |
Domoic acid neurotoxicity in cultured cerebellar granule neurons is mediated predominantly by NMDA receptors that are activated as a consequence of excitatory amino acid release.
Topics: Animals; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals.
Topics: Animals; Brain Ischemia; Caudate Nucleus; Cerebral Cortex; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Immunohistochemistry; Male; Microtubule-Associated Proteins; Nitrogen Oxides; Oligodendroglia; Quinoxalines; Rats; Rats, Inbred F344; Spin Labels; tau Proteins | 1997 |
NMDA but not AMPA receptor antagonists impair the delay-interposed radial maze performance of rats.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory, Short-Term; Pipecolic Acids; Psychomotor Performance; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Space Perception | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
The NMDA antagonist, dizocilpine, enhances cocaine reinforcement without influencing mesoaccumbens dopamine transmission.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
MK-801-induced hyperlocomotion: differential effects of M100907, SDZ PSD 958 and raclopride.
Topics: Animals; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Hyperkinesis; Male; Mice; Motor Activity; Piperidines; Quinoxalines; Raclopride; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, Serotonin; Salicylamides; Serotonin Antagonists | 1997 |
Neuronal damage and MAP2 changes induced by the glutamate transport inhibitor dihydrokainate and by kainate in rat hippocampus in vivo.
Topics: Animals; Biological Transport; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Microtubule-Associated Proteins; Neurons; Quinoxalines; Rats; Rats, Wistar | 1997 |
Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines.
Topics: Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Isomerism; Models, Chemical; N-Methylaspartate; Phencyclidine; Quinoxalines; Radioligand Assay; Rats; Receptors, AMPA; Structure-Activity Relationship; Tyrosine | 1997 |
Activation of brain nitric oxide synthase in depolarized human temporal cortex slices: differential role of voltage-sensitive calcium channels.
Topics: Alanine; Arginine; Calcium Channel Blockers; Calcium Channels; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mecamylamine; Nicotinic Antagonists; Nitric Oxide Synthase; Nitroarginine; Potassium; Potassium Chloride; Quinoxalines; Temporal Lobe | 1997 |
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E | 1997 |
Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation.
Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Hippocampus; Kynurenic Acid; Male; Muscimol; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Seizures | 1998 |
Neonatal hypothalamic c-fos expression in an excitotoxicity-induced model of precocious puberty.
Topics: Animals; Animals, Newborn; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hypothalamus; Immunohistochemistry; Models, Biological; Nerve Tissue Proteins; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sexual Maturation; Sodium Glutamate | 1997 |
Apoptosis is induced by excitotoxicity in goldfish retina.
Topics: Animals; Apoptosis; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goldfish; Kainic Acid; Microscopy, Electron; Neurons; Quinoxalines; Retina | 1997 |
Evidence for postsynaptic induction and expression of NMDA receptor independent LTP.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Axons; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Male; Membrane Potentials; Models, Neurological; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Brain neuronal degeneration caused by episodic alcohol intoxication in rats: effects of nimodipine, 6,7-dinitro-quinoxaline-2,3-dione, and MK-801.
Topics: Alcoholic Intoxication; Animals; Brain; Calcium Channel Blockers; Dentate Gyrus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1998 |
Respiratory effects of halothane and AMPA receptor antagonist synergy in rats.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Halothane; Hemodynamics; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Respiratory Mechanics | 1998 |
Excitatory amino acid antagonists alleviate convulsive and toxic properties of lindane in mice.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Felbamate; Hexachlorocyclohexane; Insecticides; Lethal Dose 50; Male; Mice; Phenylcarbamates; Propylene Glycols; Quinoxalines; Seizures | 1998 |
Excitatory amino acid receptor antagonists decrease hypoxia induced increase in extracellular dopamine in striatum of newborn piglets.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Hypoxia; Oxygen; Oxygen Consumption; Pressure; Quinoxalines; Receptors, Amino Acid; Swine | 1998 |
Role of cerebral blood flow in seizures from hyperbaric oxygen exposure.
Topics: Analysis of Variance; Animals; Cerebrovascular Circulation; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperbaric Oxygenation; Ketamine; Male; Nitric Oxide Synthase; Nitroarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 1998 |
Galanin stimulates the N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in vivo in the rat ventral hippocampus.
Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Galanin; Hippocampus; Locomotion; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptide Fragments; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1998 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
Respiratory effects of glutamate receptor antagonists in neonate and adult mammals.
Topics: Age Factors; Animals; Animals, Newborn; Apnea; Cats; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Plethysmography; Pulmonary Ventilation; Quinoxalines; Receptors, Glutamate; Species Specificity | 1998 |
Characterization of temperature rise of the brain and the rectum following intracerebroventricular administration of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Body Temperature; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indomethacin; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rectum | 1998 |
Genesis of spontaneous rhythmic motor patterns in the lumbosacral spinal cord of neonate mouse.
Topics: Animals; Animals, Newborn; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Locomotion; Magnesium; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Periodicity; Pregnancy; Quinoxalines; Spinal Cord | 1998 |
Dendrodendritic inhibition in the olfactory bulb is driven by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Magnesium; Male; Neural Inhibition; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Role of excitatory amino acid pathways in control of gonadotrophin secretion in adult female rats sterilized by neonatal administration of oestradiol or testosterone.
Topics: Animals; Animals, Newborn; Anovulation; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Kainic Acid; Luteinizing Hormone; N-Methylaspartate; Ovariectomy; Quinoxalines; Rats; Rats, Wistar; Testosterone | 1998 |
Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid.
Topics: Animals; Behavior, Animal; Convulsants; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamates; Glutarates; Injections; Male; Muscimol; Quinoxalines; Rats; Rats, Wistar; Seizures; Stereotyped Behavior | 1998 |
Calcium influx via ionotropic glutamate receptors causes long lasting inhibition of metabotropic glutamate receptor-coupled phosphoinositide hydrolysis.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Hydrolysis; Kainic Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium Fluoride | 1998 |
Increases in levels of brain-derived neurotrophic factor mRNA and its promoters after transient forebrain ischemia in the rat brain.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Dizocilpine Maleate; DNA Probes; Excitatory Amino Acid Antagonists; Exons; Gene Expression; Hippocampus; In Situ Hybridization; Ischemic Attack, Transient; Male; Mice; Promoter Regions, Genetic; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution | 1998 |
Development of calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining.
Topics: Animals; Calcium; Cells, Cultured; Cobalt; Concanavalin A; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Mice; Neocortex; Neurons; Permeability; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Staining and Labeling | 1998 |
Non-NMDA receptor antagonist-induced drinking in rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Losartan; Male; Quinoxalines; Rats; Rats, Sprague-Dawley | 1998 |
[Glutamate neurotoxicity during spinal cord ischemia--neuroprotective effects of glutamate receptor antagonists].
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Ischemia; Neuroprotective Agents; Quinoxalines; Rabbits; Spinal Cord | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzoates; Calcium; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Magnesium; Membrane Potentials; Microscopy, Confocal; Neurons; Nifedipine; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1998 |
Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.
Topics: Animals; Central Nervous System Depressants; Diazepam; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; GABA Modulators; Hypnotics and Sedatives; Indoles; Male; Midazolam; Morphine; N-Methylaspartate; Narcotics; Pentobarbital; Phencyclidine; Pregnanolone; Quinoxalines; Rats; Rats, Long-Evans; Serotonin Receptor Agonists; Water | 1997 |
The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Receptors, GABA; Synapses; Synaptic Transmission | 1998 |
An alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist and an N-methyl-D-aspartate (NMDA) channel blocker synergistically impair spatial memory in rats.
Topics: Animals; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1998 |
Sexual differences in the role of kainate receptors in controlling gonadotrophin secretion in prepubertal rats.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Orchiectomy; Ovariectomy; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sex Factors; Sexual Maturation | 1998 |
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.
Topics: Animals; Apoptosis; Brain; Calcium Channel Blockers; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Haloperidol; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Muscarinic Antagonists; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1999 |
Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion.
Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Electrocoagulation; Immunosuppressive Agents; Injections, Intraperitoneal; Injections, Intravenous; Intracranial Embolism and Thrombosis; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Tacrolimus | 1998 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture Techniques; Cytosol; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Microscopy, Fluorescence; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Sodium; Veratridine | 1998 |
Non-N-methyl-D-aspartate receptors may mediate the transmission of emetic signals between visceral vagal afferents and the solitary nucleus in dogs.
Topics: Anesthesia; Animals; Decerebrate State; Dizocilpine Maleate; Dogs; Electric Stimulation; Excitatory Amino Acid Antagonists; Lingual Nerve; Phrenic Nerve; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Salivation; Solitary Nucleus; Synaptic Transmission; Vagus Nerve; Vomiting | 1998 |
Neuroprotective interaction effects of NMDA and AMPA receptor antagonists in an in vitro model of cerebral ischemia.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypoxia; Male; Neuroprotective Agents; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Extracellular reduced glutathione increases neuronal vulnerability to combined chemical hypoxia and glucose deprivation.
Topics: Animals; Cells, Cultured; Dizocilpine Maleate; Edetic Acid; Excitatory Amino Acid Antagonists; Glucose; Glutathione; Glutathione Disulfide; Hypoxia, Brain; Mercaptoethanol; Mice; Neurons; Oxidation-Reduction; Quinoxalines; Synaptic Transmission | 1999 |
The bacterial endotoxin lipopolysaccharide causes rapid inappropriate excitation in rat cortex.
Topics: Adenosine; Age Factors; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Lipopolysaccharides; Male; Neuroprotective Agents; Norepinephrine; Organ Culture Techniques; Parietal Lobe; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sympathomimetics; Tritium | 1999 |
Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures.
Topics: Animals; Benzodiazepines; Blotting, Western; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Neocortex; Neuromuscular Depolarizing Agents; Neurotoxins; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1999 |
Neuroprotective action of a novel compound--M50463--in primary cultured neurons.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Batrachotoxins; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Neurons; Neuroprotective Agents; Neurotoxins; Nicardipine; Nitroprusside; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Thiazoles; Veratrine; Vitamin E | 1999 |
Regulation of vasopressin release by ionotropic glutamate receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Hypothalamo-Hypophyseal System; Kainic Acid; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 1998 |
Dizocilpine maleate, MK-801, but not 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline, NBQX, prevents transneuronal degeneration of nigral neurons after neurotoxic striatal-pallidal lesion.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Globus Pallidus; Ibotenic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Substantia Nigra | 1999 |
Interaction of ethanol with excitatory amino acid receptor antagonists in mice.
Topics: Animals; Ataxia; Behavior, Animal; Benzodiazepines; Central Nervous System Depressants; Chlordiazepoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoquinolines; Male; Mice; Muscle Relaxation; Pentobarbital; Piperazines; Pregnanolone; Psychomotor Performance; Quinoxalines; Receptors, Glutamate; Tetrazoles | 1999 |
Hypoxia induces c-Fos protein expression in NMDA but not AMPA glutamate receptor labeled neurons within the nucleus tractus solitarii of the conscious rat.
Topics: Air; Amino Acid Sequence; Animals; Cell Hypoxia; Consciousness; Dizocilpine Maleate; Gene Expression Regulation; Male; Molecular Sequence Data; Neurons; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1999 |
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Retina | 1999 |
Excitotoxicity plays a role in the death of tyrosine hydroxylase- immunopositive nigral neurons cultured in serum-free medium.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Channel Blockers; Cell Death; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dizocilpine Maleate; Embryo, Mammalian; Flunarizine; Mesencephalon; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1999 |
Opposite modulation of cortical N-methyl-D-aspartate receptor-mediated responses by low and high concentrations of dopamine.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Postmortem elevation in extracellular glutamate in the rat hippocampus when brain temperature is maintained at physiological levels: implications for the use of human brain autopsy tissues.
Topics: Animals; Autopsy; Body Temperature Regulation; Brain; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Male; Microdialysis; Postmortem Changes; Quinoxalines; Rats; Rats, Sprague-Dawley; Taurine | 1999 |
Biphasic expression of TGF-beta1 mRNA in the rat brain following permanent occlusion of the middle cerebral artery.
Topics: Animals; Arterial Occlusive Diseases; Brain; Cerebral Arteries; Chronic Disease; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Inbred F344; RNA, Messenger; Transforming Growth Factor beta | 1999 |
The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP+.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Kynurenic Acid; Microinjections; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1999 |
Ionotropic glutamate receptor modulation of 5-HT6 and 5-HT7 mRNA expression in rat brain.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Serotonin; RNA, Messenger; Schizophrenia | 1999 |
Beta-amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Neocortex; Neurons; Peptide Fragments; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1999 |
Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-D-aspartate receptors and glucocorticoids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cortical Spreading Depression; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Disease Susceptibility; Dizocilpine Maleate; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Indomethacin; Isoenzymes; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Parietal Lobe; Phospholipases A; Phospholipases A2; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcriptional Activation | 1999 |
Selective glutamate receptor antagonists can induce or prevent axonal sprouting in rat hippocampal slice cultures.
Topics: Animals; Axons; Culture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GAP-43 Protein; Glial Fibrillary Acidic Protein; Hippocampus; Nerve Regeneration; Piperazines; Quinoxalines; Rats; Rats, Wistar | 1999 |
Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.
Topics: 2-Amino-5-phosphonovalerate; Astrocytes; Brain; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Fetus; Gallic Acid; Gene Products, tat; HIV-1; Humans; Inositol 1,4,5-Trisphosphate; Ketamine; Neurons; Neurotoxins; Pertussis Toxin; Quinoxalines; tat Gene Products, Human Immunodeficiency Virus; Thapsigargin; Video Recording; Virulence Factors, Bordetella | 1999 |
Do nuclear condensation or fragmentation and DNA fragmentation reflect the mode of neuronal death?
Topics: Animals; Cell Death; Cerebellum; Colchicine; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Glucose; In Situ Nick-End Labeling; Microscopy, Confocal; Neurons; Oxygen; Quinoxalines; Rats; Rats, Wistar | 1999 |
NMDA receptor-mediated control of GABA release from neurointermediate lobes of female and male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Ovariectomy; Pituitary Gland, Posterior; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Double-tracer autoradiographic study of protein synthesis and glucose consumption in rats with focal cerebral ischemia.
Topics: Animals; Autoradiography; Blood Pressure; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Ischemic Attack, Transient; Leucine; Male; Nerve Tissue Proteins; Quinoxalines; Radioisotope Dilution Technique; Rats; Rats, Wistar; Reference Values; Tritium | 1999 |
1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Bridged Bicyclo Compounds; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Indans; Ischemic Attack, Transient; Mice; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
NMDA and AMPA glutamate receptor subtypes in the thoracic spinal cord in lean and obese-diabetic ob/ob mice.
Topics: Animals; Autoradiography; Dizocilpine Maleate; Female; Kinetics; Male; Mice; Mice, Obese; Neurons; Obesity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Spinal Cord; Thinness; Tritium | 1999 |
Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid.
Topics: Animals; Apoptosis; Caspases; Corpus Striatum; Decerebrate State; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mitochondria; Nervous System; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Superoxides | 2000 |
Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Chromans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Fluoresceins; Fluorescent Dyes; Iodoacetates; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2000 |
Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Memantine; Motor Activity; Piperazines; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Conserved Sequence; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Kainic Acid; Kidney; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Mutagenesis; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Receptors, Glutamate; Transfection | 2000 |
Action of locally administered NMDA and AMPA/kainate receptor antagonists in spinal cord injury.
Topics: Animals; Cerebellum; Dizocilpine Maleate; Evoked Potentials; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries | 2000 |
Electrical responses in hippocampal slices after prolonged global ischemia: effects of neuroprotectors.
Topics: Action Potentials; Animals; Brain Ischemia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2000 |
Behavioural motor effects of MK-801 and DNQX parenteral administration in adult cats: dose-response analysis. Modulatory role of dopaminergic D1 and D2 antagonists on MK-801 induced motor behaviours.
Topics: Animals; Behavior, Animal; Benzazepines; Cats; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine D1; Sulpiride | 2000 |
Opposite effects of GABA(A) and GABA(C) receptor antagonists on the b-wave of ERG recorded from the isolated rat retina.
Topics: Allylamine; Animals; Bicuculline; Dizocilpine Maleate; Electroretinography; Excitatory Amino Acid Antagonists; GABA Antagonists; Nerve Net; Organophosphonates; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Rod Photoreceptor Cells | 2000 |
Developmental regulation of subunit composition of extrasynaptic NMDA receptors in neocortical neurones.
Topics: Animals; Cells, Cultured; Coculture Techniques; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Glycine; Ion Channels; Neocortex; Neurons; Patch-Clamp Techniques; Picrotoxin; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synapses | 2000 |
Effect of ionotropic glutamate receptors antagonists on the modifications in extracellular glutamate and aspartate levels during picrotoxin seizures: a microdialysis study in freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Seizures | 2000 |
Intrastriatal administration of 5-aminolevulinic acid induces convulsions and body asymmetry through glutamatergic mechanisms.
Topics: Aminolevulinic Acid; Animals; Convulsants; Corpus Striatum; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Microinjections; Muscimol; Quinoxalines; Rats; Rats, Wistar | 2000 |
Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dicarboxylic Acids; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2000 |
Excitatory amino acids modulate epileptogenesis in the brain stem.
Topics: Animals; Brain Stem; Carbachol; Cholinergic Agonists; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Male; Microinjections; Pons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors | 2000 |
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia.
Topics: Animals; Brain Ischemia; Carotid Stenosis; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Hippocampus; In Situ Nick-End Labeling; Isoquinolines; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Tetrazoles | 2000 |
[Excitatory amino acid antagonists and potentiation of cortical evoked potentials].
Topics: Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Male; Quinoxalines; Rats; Receptors, AMPA | 1999 |
The effect of fentanyl, DNQX and MK-801 on dorsal horn neurones responsive to colorectal distension in the anaesthetized rat.
Topics: Analgesics, Opioid; Animals; Colon; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fentanyl; Male; Posterior Horn Cells; Quinoxalines; Rats; Rats, Wistar; Rectum | 2000 |
Inhibition of different pathways influencing Na(+) homeostasis protects organotypic hippocampal slice cultures from hypoxic/hypoglycemic injury.
Topics: Animals; Brain Ischemia; Cell Death; Culture Techniques; Dizocilpine Maleate; Electrophysiology; Hippocampus; Homeostasis; Hypoglycemia; Hypoxia; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Tetrodotoxin; Thiourea | 2000 |
Effects of riluzole on electrically evoked neurotransmitter release.
Topics: Acetylcholine; Animals; Calcium; Dicarboxylic Acids; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Mice; Neostriatum; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Riluzole; Serotonin; Tetrodotoxin; Tritium | 2000 |
Role of central glutamate receptors, nitric oxide and soluble guanylyl cyclase in the inhibition by endotoxin of rat gastric acid secretion.
Topics: Animals; Benzoates; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Glycine; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pentagastrin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solubility; Stomach; Vagotomy | 2000 |
Effect of pretreatment with intrathecal excitatory amino acid receptor antagonists on the development of pain behavior caused by plantar incision.
Topics: Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Foot; Halothane; Injections, Spinal; Male; Motor Activity; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley | 2000 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium | 2000 |
Mediation of ionotropic glutamate receptors in domoic acid-induced striatal dopamine release in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Homovanillic Acid; Kainic Acid; Male; Microdialysis; Neuromuscular Depolarizing Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2000 |
Regulation of prolactin secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Depression, Chemical; Dizocilpine Maleate; Male; Pituitary Gland; Prolactin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sexual Maturation | 2000 |
Glutamatergic drugs exacerbate symptomatic behavior in a transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder.
Topics: Animals; Cerebral Cortex; Comorbidity; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Limbic System; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Seizures; Tourette Syndrome | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons.
Topics: Animals; Apoptosis; Bilirubin; Caspases; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Indoles; Male; Neurons; Oligopeptides; Pregnancy; Prosencephalon; Protein Kinase C; Protein Synthesis Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thymidine; Tritium | 2000 |
Ganglion cell loss after optic nerve crush mediated through AMPA-kainate and NMDA receptors.
Topics: Animals; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Nerve Crush; Neuroprotective Agents; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells | 2000 |
Serotonin-mediated striatal dopamine release involves the dopamine uptake site and the serotonin receptor.
Topics: Animals; Bicuculline; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Ketanserin; Male; Methiothepin; Mice; Mice, Inbred C57BL; Oxymetazoline; Piperazines; Quinoxalines; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Ca2+-dependent kainate excitotoxicity in the chick embryonic neural retina ex vivo.
Topics: Animals; Calcium; Chick Embryo; Chlorides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; L-Lactate Dehydrogenase; Quinoxalines; Retina | 2000 |
NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus.
Topics: Animals; Brain Ischemia; Cell Division; Dentate Gyrus; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Gerbillinae; Glutamic Acid; Male; Memory; Microinjections; Neurons; Neuroprotective Agents; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapsins | 2000 |
N-methyl-D-aspartate receptor activation results in regulation of extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apototic-like death.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclosporine; Dizocilpine Maleate; Egtazic Acid; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nifedipine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Magnesium deprivation decreases cellular reduced glutathione and causes oxidative neuronal death in murine cortical cultures.
Topics: Animals; Cell Death; Cerebral Cortex; Coculture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Glutathione; Lipid Peroxidation; Magnesium; Mice; Neuroglia; Neurons; Neurotoxins; Oxidative Stress; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Dual role of glutamatergic neurotransmission on amyloid beta(1-42) aggregation and neurotoxicity in embryonic avian retina.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Peptide Fragments; Quinoxalines; Retina | 2001 |
Blockade of AMPA/kainate receptors can either decrease or increase the survival of cultured neocortical cells depending on the stage of maturation.
Topics: Animals; Benzodiazepines; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Kainic Acid; N-Methylaspartate; Neocortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2001 |
The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures.
Topics: Animals; Coloring Agents; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Propidium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Staining and Labeling | 2001 |
[The relation between changes of nitric oxide synthase in hippocampus and activities of excitatory amino acid receptor during epilepsy].
Topics: Animals; Dizocilpine Maleate; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Penicillin G; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2001 |
A metabotropic glutamate receptor antagonist, alpha-methyl-4-carboxyphenylglycine, attenuates immediate early gene mRNA expression following traumatic injury in cultured rat cortical glial cells.
Topics: Animals; Benzoates; Brain Injuries; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation; Genes, Immediate-Early; Gliosis; Glycine; Nerve Regeneration; Neuroglia; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcriptional Activation | 2001 |
Local immune regulation in the central nervous system by substance P vs. glutamate.
Topics: Animals; Antiviral Agents; Brain Stem; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Histocompatibility Antigens Class II; Interferon-gamma; Male; Microglia; Neuroimmunomodulation; Quinoxalines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Substance P | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Kidney; Lactic Acid; Maternal Behavior; Microdialysis; Pyruvic Acid; Quinoxalines; Rats; Receptors, Glutamate; Survival Rate; Treatment Outcome | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
TNF-alpha-induced c-Fos generation in the nucleus of the solitary tract is blocked by NBQX and MK-801.
Topics: Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Microinjections; Neurons; Oxytocin; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Solitary Nucleus; Tumor Necrosis Factor-alpha | 2001 |
Glutaminergic vagal afferents may mediate both retching and gastric adaptive relaxation in dogs.
Topics: Action Potentials; Animals; Catheterization; Dizocilpine Maleate; Dogs; Esophagus; Excitatory Amino Acid Antagonists; Ganglionic Blockers; Glutamic Acid; Hexamethonium; Neurons, Afferent; Quinoxalines; Reflex; Solitary Nucleus; Stomach; Vagotomy; Vagus Nerve; Vomiting | 2001 |
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.
Topics: Animals; Azo Compounds; Coloring Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extremities; Glutamic Acid; Glutamine; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroarginine; Nociceptors; Penicillamine; Quinoxalines; Trypan Blue | 2002 |
Long-lasting synaptic modification in the rat hippocampus resulting from NMDA receptor blockade during development.
Topics: Animals; Behavior, Animal; Cell Differentiation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Long-Term Potentiation; Neuronal Plasticity; Neurons; Organ Culture Techniques; Piperazines; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2002 |
Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity.
Topics: Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Carbazoles; Cerebral Cortex; Clonidine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Models, Neurological; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phenazocine; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Scopolamine | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species.
Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Chlorodiphenyl (54% Chlorine); Cyclosporine; Cytoplasmic Granules; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2002 |
Ammonia-induced extracellular accumulation of taurine in the rat striatum in vivo: role of ionotropic glutamate receptors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Ammonium Chloride; Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glutamine; Male; Microdialysis; Quinoxalines; Rats; Receptors, Glutamate; Taurine | 2002 |
Modulation of ET(B) receptor-induced arginine-vasopressin secretion by N-methyl-D-aspartate (NMDA) and gamma-aminobutyric acid (GABA)-dependent mechanisms in hypothalamo-neurohypophysial explants.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Arginine Vasopressin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Excitatory Amino Acid Antagonists; GABA Agonists; Hypothalamus; Male; Muscimol; Organ Culture Techniques; Peptide Fragments; Peptides, Cyclic; Phenoxybenzamine; Pituitary Gland, Posterior; Quinoxalines; Rats; Rats, Long-Evans; Receptor, Endothelin B; Receptors, Endothelin; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Secretory Rate | 2002 |
NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury.
Topics: Animals; Dizocilpine Maleate; Female; Glucose; Glutamic Acid; Injections, Spinal; Lipid Peroxidation; Mitochondria; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances; Thoracic Vertebrae | 2002 |
Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons.
Topics: Animals; Apomorphine; Behavior, Animal; Columbidae; Discrimination Learning; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections; Nucleus Accumbens; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Stimulation, Chemical | 2002 |
Secretory phospholipase A2-mediated neuronal cell death involves glutamate ionotropic receptors.
Topics: Animals; Arachidonic Acid; Astrocytes; Body Temperature; Brain; Cell Death; Cells, Cultured; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fetus; Group II Phospholipases A2; Humans; Neostriatum; Neurons; Phospholipases A; Phospholipases A2; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Blockade of ionotropic glutamatergic transmission in the ventral tegmental area reduces heroin reinforcement in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feeding Behavior; Heroin; Injections, Intraventricular; Ketamine; Locomotion; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reinforcement, Psychology; Self Administration; Time Factors; Ventral Tegmental Area | 2002 |
Involvement of NMDA receptors and a p21Ras-like guanosine triphosphatase in the constitutive activation of nuclear factor-kappa-B in cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkyl and Aryl Transferases; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Down-Regulation; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; GTP Phosphohydrolases; Imidazoles; Immunohistochemistry; Neurons; NF-kappa B; Nitroarginine; Oxadiazoles; Polyenes; Polyunsaturated Alkamides; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyridines; Pyrimidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Transcription Factor RelA | 2002 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
The epileptogenic effect of seizures induced by hypoxia: the role of NMDA and AMPA/KA antagonists.
Topics: Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Mice; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 2003 |
Both MK801 and NBQX reduce the neuronal damage after impact-acceleration brain injury.
Topics: Amyloid beta-Protein Precursor; Animals; Brain Injuries; Brain Stem; Dizocilpine Maleate; Glial Fibrillary Acidic Protein; Male; Neurons; Quinoxalines; Rats; Rats, Wistar; Thalamus | 2002 |
Role of AMPA and NMDA receptors in the nucleus accumbens shell in turning behaviour of rats: interaction with dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Injections, Intraventricular; Male; Movement; Nucleus Accumbens; Quinoxalines; Quinpirole; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2003 |
Ability of NMDA and non-NMDA receptor antagonists to inhibit cerebral ischemic damage in aged rats.
Topics: Aging; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Telencephalon | 2003 |
Prolonged expression of c-Fos and c-Jun in the cerebral cortex of rats after deltamethrin treatment.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Insecticides; Male; Nitriles; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrethrins; Quinoxalines; Rats; Rats, Sprague-Dawley | 2003 |
Networks of neurons coupled to microelectrode arrays: a neuronal sensory system for pharmacological applications.
Topics: Algorithms; Animals; Benzothiadiazines; Biosensing Techniques; Cells, Cultured; Cells, Immobilized; Chick Embryo; Chickens; Dizocilpine Maleate; Microelectrodes; Nerve Net; Quinoxalines; Signal Processing, Computer-Assisted | 2003 |
Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Models, Neurological; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Time Factors; Valine | 2003 |
Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Herbicides; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Paraquat; Parkinsonian Disorders; Quinoxalines; Rats; Rats, Wistar; Selegiline | 2003 |
Glutamate motivational ensembles in nucleus accumbens: rostrocaudal shell gradients of fear and feeding.
Topics: Animals; Avoidance Learning; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fear; Feeding Behavior; Female; Glutamic Acid; Male; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal | 2003 |
Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats.
Topics: Animals; Bridged Bicyclo Compounds; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Nicotine; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2003 |
Loss of GABAergic neuronal phenotype in primary cerebellar cultures following blockade of glutamate reuptake.
Topics: Animals; Animals, Newborn; Carrier Proteins; Cell Death; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Indicators and Reagents; Membrane Proteins; Membrane Transport Proteins; Neurofilament Proteins; Neurons; Neurotransmitter Uptake Inhibitors; Organic Anion Transporters; Organic Chemicals; Propidium; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2003 |
AMPA/kainate-type glutamate receptor antagonist reduces progressive inner hair cell loss after transient cochlear ischemia.
Topics: Acoustic Stimulation; Action Potentials; Animals; Cochlea; Cochlear Nerve; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Hair Cells, Auditory, Inner; Hearing; Immunohistochemistry; Ischemia; Male; Microscopy, Electron; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Animals, Newborn; Azepines; Cabergoline; Caspases; Cell Count; Cycloheximide; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ergolines; Excitatory Amino Acid Antagonists; Herbicides; Immunohistochemistry; Mesencephalon; NADPH Dehydrogenase; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Paraquat; Piperazines; Protein Synthesis Inhibitors; Quinoxalines; Rats; Rats, Wistar; Selegiline; Tyrosine 3-Monooxygenase | 2003 |
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycolysis; Hippocampus; Iodoacetates; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Pregnancy; Pyrrolidines; Pyruvic Acid; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2003 |
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors | 2003 |
In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors | 2003 |
The roles of different types of glutamate receptors involved in the mediation of nucleus submedius (Sm) glutamate-evoked antinociception in the rat.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus | 2003 |
Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons.
Topics: Animals; Calcium; Cattle; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Fetal Blood; Fetus; Ionomycin; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Quinoxalines; Rats; S-Nitrosothiols; Sodium Glutamate; Time Factors; Valine | 2003 |
Agmatine induces glutamate release and cell death in cultured rat cerebellar granule neurons.
Topics: Agmatine; Animals; Botulinum Toxins; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Neurons; Potassium; Quinoxalines; Rats; Tetrazolium Salts; Thiazoles | 2003 |
D,L-cis-2,3-Pyrrolidine dicarboxylate alters [3H]-L-glutamate binding and induces convulsions in mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Convulsants; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Membranes; Mice; Neuroprotective Agents; Pyrrolidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Stereoisomerism; Structure-Activity Relationship | 2003 |
The glutamatergic N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the joint contribute to the induction, but not maintenance, of arthritic pain in rats.
Topics: Animals; Arthritis, Experimental; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Joints; Male; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats.
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Reperfusion Injury | 2004 |
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Differential effects of zinc on glutamatergic and GABAergic neurotransmitter systems in the hippocampus.
Topics: Animals; Calcium Channel Blockers; Chelating Agents; Chlorides; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neural Inhibition; Neural Pathways; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Synaptic Transmission; Up-Regulation; Zinc; Zinc Compounds | 2004 |
Estradiol stimulation of pulsatile gonadotropin-releasing hormone secretion in vitro: correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo.
Topics: Aging; Animals; Animals, Newborn; Aromatase Inhibitors; Dizocilpine Maleate; Drug Administration Schedule; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; In Vitro Techniques; Male; Phthalazines; Puberty, Precocious; Quinoxalines; Rats; Rats, Wistar; Sex Characteristics; Sex Differentiation; Testosterone; Virilism | 2004 |
Role of glutamate receptors in the development and maintenance of bladder overactivity after cerebral infarction in the rat.
Topics: Animals; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Urinary Bladder Diseases | 2004 |
Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells.
Topics: alpha-Tocopherol; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cerebellum; Cytochromes c; Dizocilpine Maleate; Drug Interactions; Enzyme Activation; Flow Cytometry; Methamphetamine; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Reactive Oxygen Species | 2004 |
Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus.
Topics: Animals; Blotting, Western; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; DNA Primers; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Isoenzymes; Isoquinolines; Male; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stress, Psychological; Up-Regulation | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2004 |
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Dizocilpine Maleate; Gene Expression Regulation; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neurofibrillary Tangles; Neurons; Oligodeoxyribonucleotides; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; RNA, Messenger; Signal Transduction; tau Proteins; Tumor Suppressor Protein p53; Wnt Proteins | 2004 |
Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis.
Topics: Animals; Carbon Monoxide Poisoning; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Wakefulness | 2004 |
Ionotropic glutamate receptor antagonists inhibit the proliferation of granule cell precursors in the adult brain after seizures induced by pentylenetrazol.
Topics: Animals; Cell Count; Cell Proliferation; Dentate Gyrus; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Male; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Seizures; Stem Cells | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blockers; Cell Death; Clonazepam; Dantrolene; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; Glucose; Hippocampus; Hypoxia; In Situ Nick-End Labeling; Indoles; Intracellular Space; Ion Exchange; Lidocaine; Mibefradil; Nimodipine; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Thiazepines; Thiourea; Time Factors | 2004 |
The impact of excitotoxic blockade on the evolution of injury following combined mechanical and hypoxic insults in primary rat neuronal culture.
Topics: Animals; Anticonvulsants; Cell Hypoxia; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Female; Neurons; Pregnancy; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination.
Topics: Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Discrimination Learning; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Indoles; Midazolam; Pentobarbital; Phencyclidine; Piperazines; Pregnanolone; Quinoxalines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1B; Serotonin Receptor Agonists | 2004 |
Blockade of ionotropic glutamatergic transmission in the ventral tegmental area attenuates the physical signs of morphine withdrawal in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area; Weight Loss | 2004 |
Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons.
Topics: Age Factors; Alamethicin; Analysis of Variance; Animals; Animals, Newborn; Brain Diseases; Calcium; Calcium Isotopes; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Count; Cell Death; Cell Fractionation; Cells, Cultured; Cerebellum; Diagnostic Imaging; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; Glutamic Acid; Glycine; Hydro-Lyases; Indoles; Intracellular Space; Ionophores; Male; Mitochondria; Neurons; Propidium; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2005 |
NMDA or AMPA/kainate receptor blockade prevents acquisition of conditioned place preference induced by D(2/3) dopamine receptor stimulation in rats.
Topics: Animals; Choice Behavior; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tetrahydronaphthalenes | 2005 |
Multiple pathways of apolipoprotein E signaling in primary neurons.
Topics: Analysis of Variance; Androstadienes; Animals; Apolipoproteins E; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Models, Neurological; Nerve Tissue Proteins; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinoxalines; Signal Transduction; src-Family Kinases; Time Factors; Wortmannin | 2005 |
Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neuronal Plasticity; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
Fast neurotransmission in the rat medial preoptic nucleus.
Topics: Animals; Dizocilpine Maleate; In Vitro Techniques; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2005 |
Antinociceptive interactions between intrathecal gabapentin and MK801 or NBQX in rat formalin test.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2005 |
Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hot Temperature; Hyperalgesia; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Nociceptors; Pain, Postoperative; Physical Stimulation; Proto-Oncogene Proteins c-fos; Quinoxalines; Skin; TRPV Cation Channels | 2005 |
Mechanical loading modulates glutamate receptor subunit expression in bone.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Biomechanical Phenomena; Bone and Bones; Bone Resorption; Calcification, Physiologic; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Female; Forelimb; Immunohistochemistry; Isoenzymes; Leg Bones; Osteoclasts; Osteocytes; Pliability; Protein Subunits; Quinoxalines; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tartrate-Resistant Acid Phosphatase; Weight-Bearing | 2005 |
Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons.
Topics: Animals; Bicuculline; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diagnostic Imaging; Diltiazem; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; K Cl- Cotransporters; Muscimol; Neurons; Nimodipine; Potassium Chloride; Pregnancy; Quinoxalines; Rats; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Time Factors | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Recruitment of the Sonic hedgehog signalling cascade in electroconvulsive seizure-mediated regulation of adult rat hippocampal neurogenesis.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cell Count; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hedgehog Proteins; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Neurons; Organogenesis; Patched Receptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Seizures; Signal Transduction; Smoothened Receptor; Stem Cells; Time Factors; Trans-Activators; Veratrum Alkaloids | 2005 |
Ionotropic glutamatergic neurotransmission in the ventral tegmental area modulates DeltaFosB expression in the nucleus accumbens and abstinence syndrome in morphine withdrawal rats.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Nucleus Accumbens; Protein Isoforms; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2005 |
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Histocytochemistry; Hypoxia; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; Necrosis; Neurofilament Proteins; Neurons; Neuroprotective Agents; Propidium; Quinoxalines; Rats; Receptors, Glutamate; Time Factors | 2005 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Hypoxia in presence of blockers of excitotoxicity induces a caspase-dependent neuronal necrosis.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Caspases; Cell Survival; Cells, Cultured; Dentate Gyrus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Hypoxia; L-Lactate Dehydrogenase; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Mitochondria; Necrosis; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Sodium Cyanide | 2006 |
A rat model for acute rise in intraocular pressure: immune modulation as a therapeutic strategy.
Topics: Acute Disease; Animals; Antihypertensive Agents; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Glatiramer Acetate; Immunization; Injections; Intraocular Pressure; Male; Neuroprotective Agents; Ocular Hypertension; Optic Nerve Diseases; Peptides; Quinoxalines; Rats; Rats, Inbred Lew; Retinal Ganglion Cells; Vaccination | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Methotrexate induces seizure and decreases glutamate uptake in brain slices: prevention by ionotropic glutamate receptors antagonists and adenosine.
Topics: Adenosine; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Methotrexate; Mice; Neuroprotective Agents; Quinoxalines; Seizures | 2006 |
Different effects of nonNMDA and NMDA receptor antagonists (NBQX and dizocilpine) on cortical epileptic afterdischarges in rats.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Electroencephalography; Epilepsy; Evoked Potentials; Excitatory Amino Acid Antagonists; Quinoxalines; Rats; Rats, Wistar | 2006 |
The supramammillo-septal-hippocampal pathway mediates sensorimotor gating impairment and hyperlocomotion induced by MK-801 and ketamine in rats.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Agonists; Gait; Gait Disorders, Neurologic; Hippocampus; Ketamine; Locomotion; Male; Mammillary Bodies; Muscimol; Neural Pathways; Quinoxalines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Septal Nuclei; Time Factors | 2007 |
The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Dizocilpine Maleate; Endothelial Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Proteins; Occludin; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Threonine; Tyrosine | 2007 |
Involvement of glutamatergic receptors in the nucleus cuneiformis in modulating morphine-induced antinociception in rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Nociceptors; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 2007 |
Involvement of peripheral ionotropic glutamate receptors in activation of cutaneous branches of spinal dorsal rami following antidromic electrical stimulation of adjacent afferent nerves in rats.
Topics: Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Male; Nerve Fibers, Unmyelinated; Neural Conduction; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Skin; Spinal Nerves | 2007 |
Estrogen-mediated neuroprotection in the cortex may require NMDA receptor activation.
Topics: Analysis of Variance; Animals; Blood Pressure; Calpain; Caspase 12; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Enzyme Activation; Estrogens; Excitatory Amino Acid Agonists; Heart Rate; In Vitro Techniques; Infarction, Middle Cerebral Artery; Male; Membrane Potentials; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2007 |
Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine | 2007 |
Spinal cord ionotropic glutamate receptors function in formalin-induced nociception in preweaning rats.
Topics: Age Factors; Animals; Animals, Suckling; Behavior, Animal; Dizocilpine Maleate; Imidazoles; Motor Activity; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2007 |
NMDA receptors in preBotzinger complex neurons can drive respiratory rhythm independent of AMPA receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Magnesium; Neurons; Patch-Clamp Techniques; Periodicity; Potassium; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Respiratory Center; Respiratory Mechanics; Synaptic Transmission | 2007 |
Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation.
Topics: Alanine; Animal Testing Alternatives; Animals; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; L-Lactate Dehydrogenase; Propidium; Quinoxalines; Rats; Staining and Labeling; Tissue Culture Techniques | 2007 |
Neuroprotective effects of the AMPA antagonist PNQX in oxygen-glucose deprivation in mouse hippocampal slice cultures and global cerebral ischemia in gerbils.
Topics: Animals; Body Temperature; Cell Death; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluoresceins; Gerbillinae; Glucose; Hippocampus; Hypoxia, Brain; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; Organic Chemicals; Quinoxalines; Receptors, AMPA; Tolonium Chloride | 2007 |
Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2008 |
NMDA receptors in the rat VTA: a critical site for social stress to intensify cocaine taking.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Cocaine-Related Disorders; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Self Administration; Social Environment; Stress, Psychological; Ventral Tegmental Area | 2008 |
Activin induces long-lasting N-methyl-D-aspartate receptor activation via scaffolding PDZ protein activin receptor interacting protein 1.
Topics: Activins; Adaptor Proteins, Signal Transducing; Animals; Benzamides; Calcium; Cells, Cultured; Dioxoles; Dizocilpine Maleate; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Guanylate Kinases; Hippocampus; Immunoprecipitation; Neurons; Phosphopyruvate Hydratase; Proteins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Transfection | 2008 |
Contribution of NMDA and non-NMDA receptors to in vivo glutamate-induced calpain activation in the rat striatum. Relation to neuronal damage.
Topics: Animals; Calpain; Caspase 3; Corpus Striatum; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spectrin | 2008 |
Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder.
Topics: Acoustic Stimulation; Amantadine; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Riluzole | 2008 |
Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences.
Topics: Animals; Animals, Newborn; Dendritic Spines; Dizocilpine Maleate; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; Female; Hypothalamus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Silver Staining | 2008 |
Pharmacologic analysis of the mechanism of dark neuron production in cerebral cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Artifacts; Biopsy; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglycemia; Male; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetraethylammonium | 2008 |
The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy.
Topics: Animals; Dizocilpine Maleate; Foot; Infusions, Parenteral; Male; Models, Animal; Morphine; Narcotics; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Subarachnoid Space | 2008 |
Estradiol replacement modifies c-fos expression at the spinomedullary junction evoked by temporomandibular joint stimulation in ovariectomized female rats.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Estradiol; Estrogens; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Medulla Oblongata; Mustard Plant; Ovariectomy; Plant Oils; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Temporomandibular Joint | 2008 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; Glutamic Acid; Male; Neurons; Organophosphonates; Piperazines; Prefrontal Cortex; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Ventral Tegmental Area | 2008 |
Sodium azide induced neuronal damage in vitro: evidence for non-apoptotic cell death.
Topics: Acetylcarnitine; Animals; Antioxidants; Apoptosis; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Dizocilpine Maleate; Guanylate Cyclase; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Azide | 2009 |
The role of different glutamate receptors in the mediation of glutamate-evoked excitation of red nucleus neurons after simulated microgravity in rat.
Topics: Animals; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hindlimb Suspension; Microinjections; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Red Nucleus; Stimulation, Chemical; Weightlessness Simulation | 2008 |
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase.
Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures | 2009 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors | 2009 |
De-coupling of blood flow and metabolism in the rat brain induced by glutamate.
Topics: Amphetamines; Animals; Autoradiography; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Dizocilpine Maleate; Fluorodeoxyglucose F18; Glucose; Glutamic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2009 |
Topiramate antagonizes NMDA- and AMPA-induced seizure-like activity in planarians.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; N-Methylaspartate; Neuroprotective Agents; Planarians; Quinoxalines; Seizures; Topiramate | 2009 |
Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Organoselenium Compounds; Pentylenetetrazole; Pilocarpine; Quinoxalines; Rats; Rats, Wistar; Seizures; Time Factors; Treatment Outcome | 2009 |
Effects of quetiapine on monoamine, GABA, and glutamate release in rat prefrontal cortex.
Topics: Action Potentials; Analysis of Variance; Animals; Antipsychotic Agents; Biogenic Monoamines; Chromatography, Liquid; Dibenzothiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Neurons; Prefrontal Cortex; Quetiapine Fumarate; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Arcopallium, NMDA antagonists and ingestive behaviors in pigeons.
Topics: Amygdala; Analysis of Variance; Animals; Columbidae; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drinking; Eating; Feeding Behavior; Male; Prosencephalon; Quinoxalines; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2009 |
The time course of dopamine transmission in the ventral tegmental area.
Topics: Animals; Biophysics; Chelating Agents; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Egtazic Acid; Electric Stimulation; Electrochemistry; Excitatory Amino Acid Antagonists; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred DBA; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Quinpirole; Rhodamines; Signal Transduction; Statistics, Nonparametric; Temperature; Time Factors; Ventral Tegmental Area | 2009 |
N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Inosine; N-Methylaspartate; Neurons; Piperidines; Purines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2009 |
In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus.
Topics: Animals; CA1 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Electrochemical Techniques; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microelectrodes; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain.
Topics: Age Factors; Analysis of Variance; Animals; Brain; Cell Count; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Quinoxalines; Seizures; Severity of Illness Index; Species Specificity | 2010 |
Glutamate enhances the surface distribution and release of Munc18 in cerebral cortical neurons.
Topics: Animals; Biotinylation; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; L-Lactate Dehydrogenase; Munc18 Proteins; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
Stress-induced priming of glutamate synapses unmasks associative short-term plasticity.
Topics: Animals; Biophysical Phenomena; Biophysics; Chelating Agents; Corticotropin-Releasing Hormone; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exocytosis; Freezing Reaction, Cataleptic; Glutamic Acid; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; SNARE Proteins; Stress, Physiological; Synapses; Time Factors | 2010 |
The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.
Topics: Aconitine; Amphetamine; Animals; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Varenicline | 2011 |
Differential expression and sensitivity of presynaptic and postsynaptic opioid receptors regulating hypothalamic proopiomelanocortin neurons.
Topics: Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; Benzeneacetamides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression; Hypothalamus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naltrexone; Narcotic Antagonists; Neural Inhibition; Neurons; Patch-Clamp Techniques; Peptide Fragments; Pro-Opiomelanocortin; Pyrrolidines; Quinoxalines; Receptors, Opioid; Somatostatin; Synapses | 2011 |
Kainate administered to adult zebrafish causes seizures similar to those in rodent models.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Quinoxalines; Rats; Receptors, Glutamate; Seizures; Zebrafish | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.
Topics: Animals; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Mice; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2011 |
Glucose starvation stimulates Zn2+ toxicity in cultures of cerebellar granule neurons.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cerebellum; Chlorides; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Ruthenium Red; Zinc Compounds | 2012 |
Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats.
Topics: Animals; Biguanides; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Spermidine | 2012 |
NMDARs mediate the role of monoamine oxidase A in pathological aggression.
Topics: Aggression; Animals; Antisocial Personality Disorder; Autoradiography; Binding Sites; Blotting, Western; Corpus Striatum; Dizocilpine Maleate; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Mice; Mice, Knockout; Monoamine Oxidase; Motor Activity; Norepinephrine; Patch-Clamp Techniques; Phenols; Piperidines; Prosencephalon; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Serotonin | 2012 |
State-dependent increase of cortical gamma activity during REM sleep after selective blockade of NR2B subunit containing NMDA receptors.
Topics: Animals; Arousal; Brain Waves; Dizocilpine Maleate; Electroencephalography; Ketamine; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sleep, REM | 2012 |
[MK-801 or DNQX reduces electroconvulsive shock-induced impairment of learning-memory and hyperphosphorylation of Tau in rats].
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Learning; Memory; Memory Disorders; Phosphorylation; Quinoxalines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; tau Proteins | 2012 |
Selective activation of group III metabotropic glutamate receptor subtypes produces different patterns of γ-aminobutyric acid immunoreactivity and glutamate release in the retina.
Topics: Amacrine Cells; Anilides; Animals; Benzhydryl Compounds; Calcium; Chickens; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; GABA Plasma Membrane Transport Proteins; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Nipecotic Acids; Oximes; Phosphoserine; Quinoxalines; Receptors, Metabotropic Glutamate | 2012 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Cognitive improvement by acute growth hormone is mediated by NMDA and AMPA receptors and MEK pathway.
Topics: Age Factors; Aminoacetonitrile; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Growth Hormone; Male; MAP Kinase Signaling System; Memory, Short-Term; Mice; Protease Inhibitors; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2013 |
Low doses of the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, induces social facilitation in adolescent male rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Social Facilitation | 2013 |
The effects of an acute challenge with the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, on social inhibition in adolescent and adult male rats.
Topics: Aging; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibition, Psychological; Male; Motor Activity; Piperidines; Quinoxalines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Social Behavior | 2014 |
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat.
Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus | 2014 |
Varenicline disrupts prepulse inhibition only in high-inhibitory rats.
Topics: Acoustic Stimulation; Acoustics; Analysis of Variance; Animals; Apomorphine; Benzazepines; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Nicotine; Nicotinic Agonists; Prepulse Inhibition; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Varenicline | 2014 |
Hyperbaric pressure and increased susceptibility to glutamate toxicity in retinal ganglion cells in vitro.
Topics: Animals; bcl-2-Associated X Protein; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Pressure; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Retinal Ganglion Cells; Stress, Physiological | 2014 |
The role of GluN2A and GluN2B subunits on the effects of NMDA receptor antagonists in modeling schizophrenia and treating refractory depression.
Topics: Animals; Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phenols; Piperidines; Prefrontal Cortex; Quinoxalines; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin; Stereotyped Behavior | 2014 |
Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Differentiation; Cell Line; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophysiology; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Quinoxalines; Receptors, Ionotropic Glutamate | 2014 |
AVP and Glu systems interact to regulate levels of anxiety in BALB/cJ mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anxiety; Arginine Vasopressin; Dizocilpine Maleate; Glutamine; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyrrolidines; Quinoxalines | 2014 |
Prosurvival NMDA 2A receptor signaling mediates postconditioning neuroprotection in the hippocampus.
Topics: Analysis of Variance; Animals; Brain Ischemia; Calcium; CREB-Binding Protein; Dizocilpine Maleate; Hippocampus; Immunoprecipitation; Male; Maze Learning; Neuroprotective Agents; Phenols; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors | 2015 |
Neuroprotective effect of noscapine on cerebral oxygen-glucose deprivation injury.
Topics: Animals; Brain Ischemia; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glucose; Hypoxia; Mice; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide; Noscapine; Primary Cell Culture; Quinoxalines; Thapsigargin | 2015 |
Activity-dependent differences in function between proximal and distal Schaffer collaterals.
Topics: Action Potentials; Animals; Bicuculline; Biophysical Phenomena; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Nerve Fibers; Nerve Net; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time | 2015 |
Transient mitochondrial permeability transition mediates excitotoxicity in glutamate-sensitive NSC34D motor neuron-like cells.
Topics: Animals; Calcium Signaling; Cell Line, Transformed; Cyclosporine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hybrid Cells; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Motor Neurons; Oxidative Stress; Quinoxalines; Receptors, AMPA; Ruthenium Compounds; Time Factors; Transfection | 2015 |
Optogenetic stimulation of GABA neurons can decrease local neuronal activity while increasing cortical blood flow.
Topics: Animals; Cerebrovascular Circulation; Channelrhodopsins; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Interneurons; Lasers; Male; Mice; Optogenetics; Photic Stimulation; Quinoxalines | 2015 |
Dissociable effects of NR2A and NR2B NMDA receptor antagonism on cognitive flexibility but not pattern separation.
Topics: Animals; Association Learning; Cognition; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spatial Memory | 2015 |
Despair-associated memory requires a slow-onset CA1 long-term potentiation with unique underlying mechanisms.
Topics: Animals; CA1 Region, Hippocampal; Corticosterone; Depression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunoblotting; Ketamine; Long-Term Potentiation; Male; Memory; Mineralocorticoid Receptor Antagonists; Phosphorylation; Quinoxalines; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spironolactone; Stress, Psychological; Swimming | 2015 |
Cannabinoid Transmission in the Hippocampus Activates Nucleus Accumbens Neurons and Modulates Reward and Aversion-Related Emotional Salience.
Topics: Animals; Avoidance Learning; Benzoxazines; Cognition; Conditioning, Psychological; Dizocilpine Maleate; Emotions; Hippocampus; Male; Memory; Microinjections; Morpholines; Naphthalenes; Neurons; Nucleus Accumbens; Piperidines; Pyrazoles; Quinoxalines; Rats; Receptor, Cannabinoid, CB1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Rimonabant; Social Behavior | 2016 |
Peripheral NMDA Receptors Mediate Antidromic Nerve Stimulation-Induced Tactile Hypersensitivity in the Rat.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Electric Stimulation; Glutamic Acid; Hyperalgesia; Isoquinolines; Male; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Tibial Nerve | 2015 |
Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning.
Topics: Animals; Calcium-Binding Proteins; Carrier Proteins; Channelrhodopsins; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Forelimb; Learning; Male; Motor Cortex; Motor Skills; Muscle Strength; Neural Pathways; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Inbred F344; Reaction Time; Thalamus; Transduction, Genetic | 2016 |
Effects of NMDA-Receptor Antagonist on the Expressions of Bcl-2 and Bax in the Subventricular Zone of Neonatal Rats with Hypoxia-Ischemia Brain Damage.
Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Dizocilpine Maleate; Hypoxia-Ischemia, Brain; Immunohistochemistry; Lateral Ventricles; Neuroprotective Agents; Phenols; Piperidines; Protein Subunits; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2015 |
Involvement of protein phosphatases in the destabilization of methamphetamine-associated contextual memory.
Topics: Amygdala; Animals; Anisomycin; Calcium Signaling; Conditioning, Classical; Dendritic Spines; Dizocilpine Maleate; Male; Memory Consolidation; Mental Recall; Methamphetamine; Mice, Inbred C57BL; Phosphoprotein Phosphatases; Protein Synthesis Inhibitors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2016 |
[Analgesic effects of ionotropic glutamate receptor antagonists MK-801 and NBQX on collagen-induced arthritis rats].
Topics: Analgesics; Animals; Arthritis, Experimental; Cyclooxygenase 2; Dizocilpine Maleate; Edema; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Janus Kinase 3; Male; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Hippocampal Protein Kinase C Signaling Mediates the Short-Term Memory Impairment Induced by Delta9-Tetrahydrocannabinol.
Topics: Animals; Anisomycin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Hippocampus; Isoenzymes; Male; Memory, Short-Term; Mice; Microinjections; Neurogranin; Phenols; Phosphorylation; Piperidines; Protein Kinase C; Quinoxalines; Rimonabant; Signal Transduction; Sirolimus | 2018 |
Long-term neurotoxic effects of domoic acid on primary dopaminergic neurons.
Topics: Animals; Apoptosis; Cells, Cultured; Dizocilpine Maleate; Dopaminergic Neurons; Kainic Acid; Membrane Potential, Mitochondrial; Mesencephalon; Mice; Neuromuscular Depolarizing Agents; Neurotoxins; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2018 |
Do stereoisomers of homocysteic acid exhibit different convulsant action in immature rats?
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Dizocilpine Maleate; Homocysteine; Male; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Stereoisomerism | 2019 |
Factors regulating serine racemase and d-amino acid oxidase expression in the mouse striatum.
Topics: Animals; Brain; Cocaine; Corpus Striatum; D-Amino-Acid Oxidase; Dizocilpine Maleate; Female; Gene Expression; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinoxalines; Racemases and Epimerases; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine | 2021 |