Page last updated: 2024-08-17

quinoxalines and cyadox

quinoxalines has been researched along with cyadox in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199010 (17.86)18.7374
1990's3 (5.36)18.2507
2000's8 (14.29)29.6817
2010's30 (53.57)24.3611
2020's5 (8.93)2.80

Authors

AuthorsStudies
de Graaf, GJ; Jager, LP; Nabuurs, MJ; van der Molen, EJ1
Tokosová, M3
Bakri, A; Beyersbergen van Henegouwen, GM; Bojarski, J; de Vries, H; Donker, AA1
Baars, AJ; de Graaf, GJ; Jager, LP; van der Molen, EJ1
Pleva, J; Tokosová, M1
De Graaf, GJ; Spierenburg, TJ1
Szabová, E1
Cihák, R; Vontorková, M1
Dvorák, M1
Gandalovicová, D; Marhan, O; Sýkora, I1
Cihák, R; Srb, V1
Fang, G; He, Q; Wang, D; Yuan, Z; Zhang, Y; Zhou, S1
Chen, D; Huang, L; Tao, Y; Wang, Y; Yuan, Z; Zhang, Y1
Chen, D; Fan, S; Huang, L; Tao, Y; Wang, Y; Yuan, Z; Zhang, Y1
Fan, S; Fang, G; He, Q; Wang, D; Wang, Y; Wei, Z; Yuan, Z; Zhou, S1
Ding, MX; Fan, SX; Wang, YL; Yuan, ZH; Zhu, HL1
Ding, MX; Wang, YL; Yuan, ZH; Zhu, HL1
Chen, D; Huang, L; Tao, Y; Wang, Y; Yuan, Z1
Chen, D; Dai, M; Huang, L; Liu, Z; Tao, Y; Wang, Y; Yuan, Z1
Huang, LL; Huang, XJ; Liu, Y; Wang, X; Yan, CX; Yuan, ZH; Zhang, HH; Zhang, LY1
He, QH; Huang, LL; Ihsan, A; Liu, ZL; Su, SJ; Wang, X; Wang, YL; Yuan, ZH; Zhou, W1
Fang, GJ; Huang, LL; Ihsan, A; Liu, ZL; Wang, X; Wang, YL; Yuan, ZH; Zhou, W1
Fang, B; He, L; Liu, K; Liu, Y; Su, Y; Zeng, Z; Zhang, G; Zhang, J1
Deng, Y; Jiang, J; Ouyang, M; Tang, X; Wang, J; Zheng, M1
Chen, D; Huang, L; Liu, Z; Pan, Y; Peng, D; Tao, Y; Wang, X; Wang, Y; Xu, N; Yuan, Zh1
Dai, M; Guo, W; Hao, H; Huang, L; Liu, Z; Peng, D; Sun, Y; Wang, H; Wang, X; Wang, Y; Yao, M; Yuan, Z1
Huang, C; Lei, H; Tang, H; Wang, Y; Zhao, X1
Liu, ZY; Sun, ZL1
Cheng, G; Huang, L; Ihsan, A; Iqbal, Z; Liu, Z; Pan, Y; Tan, Z; Tu, H; Wang, X; Wang, Y; Yuan, Z; Zhang, W; Zhang, Y1
Cheng, G; Dai, M; Guo, W; Hao, H; Huang, L; Iqbal, Z; Liu, Z; Peng, D; Wang, X; Wang, Y; Yuan, Z1
Chen, C; Cheng, G; Dai, M; Hao, H; Huang, L; Liu, Z; Wang, X; Yuan, Z1
Ding, H; Fang, B; Gu, X; Li, Y; Yang, F; Zeng, Z; Zhang, B; Zhao, N1
Dongmei, C; Harnud, S; Lingli, H; Ning, X; Yanfei, T; Yuanhu, P; Zhenli, L; Zonghui, Y1
Cheng, G; Dai, M; Hao, H; Li, B; Liang, G; Liu, Z; Wang, C; Wang, X; Wang, Y; Weng, Z; Yuan, Z; Zhang, H1
Chen, D; Cheng, G; Hao, H; Ihsan, A; Liu, Z; Wang, X; Wang, Y; Yuan, Z; Zhou, W1
Gehring, R; Huang, L; Lin, Z; Riviere, JE; Yuan, Z; Zhou, X; Zhu, M1
Chen, D; Cheng, G; Guo, P; Hao, H; Huang, Q; Ihsan, A; Jamil, F; Luo, X; Tao, Y; Wang, X; Yuan, Z1
Chen, D; Cheng, G; Dai, M; Guo, P; Ihsan, A; Liu, Z; Luo, X; Wang, X; Yang, C; Yuan, Z1
Alagawany, M; Farag, MR; Tufarelli, V1
Awais, I; Cui, L; Dai, M; Lei, Z; Liu, Q; Wang, X; Yuan, Z; Zhang, J1
Chen, D; Huang, L; Jiang, L; Liu, Z; Pan, Y; Sattar, A; Tao, Y; Xie, S; Yuan, Z1
Huang, LL; Li, J; Pan, YH; Qiu, YM; Sun, LL; Wang, YL; Yuan, ZH1
Cheng, G; Cui, L; Dai, M; Liu, Z; Lu, Q; Wang, X; Wang, Y; Yu, R; Yuan, Z; Zhang, Y1
Li, H; Miao, X; Xu, L; Yang, Z1
Alagawany, M; El-Hack, MEA; Farag, MR; Tufarelli, V1
Harnud, S; Yuan, Z; Zhang, A1
Dai, M; Lei, Z; Liu, Q; Liu, S; Sun, Q; Wang, X; Yu, H; Yuan, Z; Zhou, K1
Cheng, G; Cui, L; Dai, M; Hao, H; Huang, D; Huang, L; Li, D; Liu, Z; Lu, Q; Peng, D; Wang, X; Wang, Y; Xing, D; Yuan, Z1
Bakr Shabbir, MA; Dai, M; Huang, L; Maan, MK; Xu, D; Yuan, Z1
Chen, D; Hafeez, MA; Huang, L; Sattar, A; Shabbir, MAB; Tahir, AH; Wu, Q; Xie, S; Yuan, Z1
Cheng, G; Cui, L; Dai, M; Guo, J; Liu, Z; Lu, Q; Wang, X; Wang, Y; Zhao, H1
Chen, D; Liu, S; Liu, Z; Meng, K; Pan, Y; Qu, W; Xie, S; Yue, T1
Fu, S; Harnud, S; Huang, L; Pan, Y; Wang, Y; Zhang, A1
Huang, C; Lei, H; Liu, C; Wang, Y1

Reviews

1 review(s) available for quinoxalines and cyadox

ArticleYear
The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:8

    Topics: Animals; Carbadox; Humans; Quinoxalines

2013

Trials

3 trial(s) available for quinoxalines and cyadox

ArticleYear
Effects of cyadox and olaquindox on intestinal mucosal immunity and on fecal shedding of Escherichia coli in piglets.
    Journal of animal science, 2006, Volume: 84, Issue:9

    Topics: Animals; Escherichia coli; Feces; Immunity, Mucosal; Immunologic Factors; Intestinal Mucosa; Male; Quinoxalines; Swine

2006
Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration.
    Journal of agricultural and food chemistry, 2013, Oct-02, Volume: 61, Issue:39

    Topics: Animals; Biomarkers; Biotransformation; China; Chromatography, High Pressure Liquid; Crosses, Genetic; Drug Residues; Food Additives; Food Contamination; Food Inspection; Kidney; Male; Meat; Quinoxalines; Sus scrofa; Tandem Mass Spectrometry; Tissue Distribution

2013
Disposition of cyadox in domesticated cats following oral, intramuscular, and intravenous administration.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Cats; Cross-Over Studies; Feces; Female; Half-Life; Injections, Intramuscular; Male; Quinoxalines

2020

Other Studies

52 other study(ies) available for quinoxalines and cyadox

ArticleYear
Clinical signs and performance of pigs treated with different doses of carbadox, cyadox and olaquindox.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1990, Volume: 37, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Carbadox; Female; Hematocrit; Male; Quinoxalines; Swine; Weight Gain

1990
[The effect of cyadox and virginiamycin on Marek's disease in chickens].
    Veterinarni medicina, 1990, Volume: 35, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chickens; Marek Disease; Poultry Diseases; Quinoxalines; Virginiamycin

1990
Photochemical reactions of quindoxin, olaquindox, carbadox and cyadox with protein, indicating photoallergic properties.
    Toxicology, 1990, Volume: 63, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Carbadox; Chemical Phenomena; Chemistry; Humans; Organophosphorus Compounds; Photochemistry; Photosensitivity Disorders; Proteins; Quinoxalines; Serum Albumin; Ultraviolet Rays

1990
[The effect of growth stimulators on the levels of various macroelements in chickens].
    Veterinarni medicina, 1989, Volume: 34, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Chickens; Electrolytes; Growth Substances; Nitrovin; Quinoxalines; Tissue Distribution; Virginiamycin

1989
[The effect of growth stimulators on the levels of various trace elements in chickens].
    Veterinarni medicina, 1989, Volume: 34, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Chickens; Growth Substances; Nitrovin; Quinoxalines; Tissue Distribution; Trace Elements; Virginiamycin

1989
Comparative study of the effect of the effect of carbadox, olaquindox and cyadox on aldosterone, sodium and potassium plasma levels in weaned pigs.
    Research in veterinary science, 1989, Volume: 47, Issue:1

    Topics: Aldosterone; Animal Feed; Animals; Anti-Bacterial Agents; Carbadox; Female; Male; Potassium; Quinoxalines; Sodium; Swine

1989
[The effect of growth stimulators on the health status and growth of broilers].
    Veterinarni medicina, 1988, Volume: 33, Issue:5

    Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Chickens; Growth Substances; Nitrofurans; Nitrovin; Quinoxalines

1988
Liquid chromatographic determination of cyadox in medicated feeds and in the contents of the porcine gastrointestinal tract with fluorescence detection.
    Journal of chromatography, 1988, Aug-05, Volume: 447, Issue:1

    Topics: Animal Feed; Animals; Duodenum; Food Additives; Gastrointestinal Contents; Quinoxalines; Spectrometry, Fluorescence; Swine

1988
[Cytogenetic effects of non-antibiotic growth stimulators on bone marrow cells in mice].
    Bratislavske lekarske listy, 1988, Volume: 89, Issue:5

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbadox; Chromosome Aberrations; Growth Substances; Male; Mice; Mice, Inbred ICR; Quinoxalines

1988
Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. III. Transplacental micronucleus test in mice.
    Mutation research, 1985, Volume: 144, Issue:2

    Topics: Administration, Oral; Animals; Bone Marrow; Carbadox; Cell Nucleus; Female; Fetus; Injections, Intraperitoneal; Liver; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy; Quinoxalines

1985
[Increasing the effectiveness of feed mixtures for the early weaning of piglets with the addition of fats or growth stimulators].
    Veterinarni medicina, 1984, Volume: 29, Issue:3

    Topics: Animal Feed; Animals; Dietary Fats; Growth Substances; Quinoxalines; Swine; Weaning

1984
[The effect of the non-antibiotic growth stimulators, Carbadox and Cyadox, on reproduction in laboratory animals].
    Veterinarni medicina, 1981, Volume: 26, Issue:6

    Topics: Animals; Carbadox; Female; Fertility; Fetal Death; Fetus; Growth Substances; Male; Pregnancy; Pregnancy, Animal; Quinoxalines; Rats; Spermatogenesis

1981
Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. I. Micronucleus test in rats.
    Mutation research, 1983, Volume: 116, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bone Marrow; Carbadox; Cell Nucleus; Erythrocytes; Male; Mutagenicity Tests; Mutagens; Mutation; Quinoxalines; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1983
Subchronic oral toxicity study with cyadox in Wistar rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:1

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Body Weight; Diet; Dose-Response Relationship, Drug; Epithelial Cells; Female; Hepatocytes; Kidney Tubules, Proximal; Male; No-Observed-Adverse-Effect Level; Quinoxalines; Rats; Rats, Wistar

2006
Effects of cooking and storage on residues of cyadox in chicken muscle.
    Journal of agricultural and food chemistry, 2005, Dec-14, Volume: 53, Issue:25

    Topics: Animals; Chickens; Cooking; Drug Residues; Drug Stability; Food Preservation; Half-Life; Hot Temperature; Muscles; Quinoxalines

2005
Development of HPLC methods for the determination of cyadox and its main metabolites in goat tissues.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2005, Volume: 21, Issue:12

    Topics: Animals; Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Goats; Quinoxalines; Reproducibility of Results; Sensitivity and Specificity

2005
Experimental evaluation of cyadox phototoxicity to Balb/c mouse skin.
    Photodermatology, photoimmunology & photomedicine, 2006, Volume: 22, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Erythema; Mice; Mice, Inbred BALB C; Quinoxalines; Skin; Ultraviolet Rays

2006
Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunity of piglets orally inoculated with Escherichia coli.
    Journal of animal physiology and animal nutrition, 2006, Volume: 90, Issue:5-6

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Energy Intake; Escherichia coli; Immunoglobulin A; Intestinal Mucosa; Lymphocyte Count; Quinoxalines; Random Allocation; Swine; Weight Gain

2006
Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Oct-15, Volume: 874, Issue:1-2

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Fats; Kidney; Liver; Molecular Structure; Muscles; Quinoxalines; Reproducibility of Results

2008
Metabolism of cyadox in rat, chicken and pig liver microsomes and identification of metabolites by accurate mass measurements using electrospray ionization hybrid ion trap/time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:13

    Topics: Animals; Biotransformation; Chickens; Chromatography, High Pressure Liquid; Growth Substances; Male; Microsomes, Liver; Quinoxalines; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Swine

2009
ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro.
    Chemico-biological interactions, 2010, May-14, Volume: 185, Issue:3

    Topics: Adrenal Cortex; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Mitochondria; Molecular Structure; Oxidation-Reduction; Quinoxalines; Reactive Oxygen Species; Swine; Time Factors

2010
A chronic toxicity study of cyadox in Wistar rats.
    Regulatory toxicology and pharmacology : RTP, 2011, Volume: 59, Issue:2

    Topics: Animals; Body Weight; Eating; Female; Kidney; Liver; Male; No-Observed-Adverse-Effect Level; Organ Size; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Toxicity Tests, Chronic; Transaminases

2011
Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:5

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epididymis; Female; Fetal Development; Male; Maternal Exposure; No-Observed-Adverse-Effect Level; Organ Size; Pregnancy; Quinoxalines; Rats; Rats, Wistar; Reproduction; Teratogens; Testis

2011
Simultaneous determination of cyadox and its metabolites in plasma by high-performance liquid chromatography tandem mass spectrometry.
    Journal of separation science, 2011, Volume: 34, Issue:15

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Molecular Structure; Quinoxalines; Tandem Mass Spectrometry

2011
The mechanism of enzymatic and non-enzymatic N-oxide reductive metabolism of cyadox in pig liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:11

    Topics: Animals; Catalase; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytosol; Hemeproteins; Liver; Microsomes, Liver; Oxidation-Reduction; Oxides; Quinoxalines; Recombinant Proteins; Sus scrofa

2011
Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2011, Aug-30, Volume: 25, Issue:16

    Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Colon; Hydrolysis; Ileum; Intestinal Mucosa; Male; Mass Spectrometry; Microsomes; Oxidation-Reduction; Quinoxalines; Swine

2011
Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Base Sequence; DNA Primers; DNA, Complementary; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Glycolysis; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Nucleic Acid Hybridization; Oxides; Phenotype; Phosphorylation; Polymerase Chain Reaction; Quinoxalines; Swine

2012
Metabolic influence of acute cyadox exposure on Kunming mice.
    Journal of proteome research, 2013, Jan-04, Volume: 12, Issue:1

    Topics: Amino Acids; Animals; Dimethylamines; Food Safety; Hippurates; Kidney Medulla; Liver; Methylamines; Mice; Nucleotides; Quinoxalines

2013
Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Animals; Anti-Infective Agents; Bone Marrow Cells; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA Replication; Dose-Response Relationship, Drug; Humans; Lymphocytes; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Mutagens; Mutation; Quinoxalines; Random Allocation; Salmonella typhimurium

2013
Impact of cyadox on human colonic microflora in chemostat models.
    Regulatory toxicology and pharmacology : RTP, 2013, Volume: 67, Issue:3

    Topics: Anti-Infective Agents; Bacteroides fragilis; Bifidobacterium; Colon; Drug Resistance, Bacterial; Enterococcus; Escherichia coli; Feces; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Models, Biological; No-Observed-Adverse-Effect Level; Quinoxalines; Salmonella typhimurium; Veterinary Drugs

2013
Mechanism of porcine liver xanthine oxidoreductase mediated N-oxide reduction of cyadox as revealed by docking and mutagenesis studies.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Binding Sites; Cloning, Molecular; Enzyme Activation; Gene Expression; Kinetics; Liver; Male; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Protein Conformation; Quinoxalines; Recombinant Proteins; Swine; Xanthine Dehydrogenase

2013
Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats.
    Journal of agricultural and food chemistry, 2015, Jun-10, Volume: 63, Issue:22

    Topics: Animals; Anti-Infective Agents; Biological Transport; Carps; Chickens; Drug Residues; Female; Food Contamination; Food Safety; Kidney; Liver; Male; Meat; Molecular Structure; Muscles; Quinoxalines; Rats; Rats, Wistar; Swine; Tissue Distribution

2015
Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Anti-Bacterial Agents; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Annotation; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Proteomics; Quinoxalines; Reactive Oxygen Species; SOS Response, Genetics; Structure-Activity Relationship; Tirapazamine; Triazines

2015
Assessment of thirteen-week subchronic oral toxicity of cyadox in Beagle dogs.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 73, Issue:2

    Topics: Administration, Oral; Animals; Body Weight; Dogs; Eating; Female; Male; No-Observed-Adverse-Effect Level; Organ Size; Quinoxalines; Time Factors; Toxicity Tests, Subchronic

2015
Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modelling.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2015, Volume: 32, Issue:12

    Topics: Adipose Tissue; Animal Feed; Animals; Anti-Infective Agents; Biotransformation; Chromatography, Liquid; Drug Residues; Food Analysis; Kidney; Liver; Models, Statistical; Monte Carlo Method; Muscle, Skeletal; Quinoxalines; Swine; Tandem Mass Spectrometry; Veterinary Drugs

2015
Evaluation of the safety of primary metabolites of cyadox: Acute and sub-chronic toxicology studies and genotoxicity assessment.
    Regulatory toxicology and pharmacology : RTP, 2016, Volume: 74

    Topics: Animals; Anti-Infective Agents; Biomarkers; Biotransformation; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Liver; Male; Maximum Tolerated Dose; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Organ Size; Quinoxalines; Rats, Wistar; Risk Assessment; Time Factors; Toxicity Tests, Acute; Toxicity Tests, Subchronic; Weight Loss

2016
High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.
    Toxicology, 2016, Feb-03, Volume: 341-343

    Topics: Adrenal Gland Diseases; Aldosterone; Antioxidants; Biotransformation; Cell Line; Cell Survival; Cytochrome P-450 CYP11B2; Humans; Oxidative Stress; Proanthocyanidins; Quinoxalines; RNA, Messenger; Steroid 11-beta-Hydroxylase

2016
In vitro antioxidant activities of resveratrol, cinnamaldehyde and their synergistic effect against cyadox-induced cytotoxicity in rabbit erythrocytes.
    Drug and chemical toxicology, 2017, Volume: 40, Issue:2

    Topics: Acrolein; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cytoprotection; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Enzymes; Eryptosis; Erythrocytes; Glutathione; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Picrates; Protein Carbonylation; Quinoxalines; Rabbits; Resveratrol; Stilbenes

2017
A two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 87

    Topics: Animals; Anti-Infective Agents; Carcinogenicity Tests; Diet; Female; Male; No-Observed-Adverse-Effect Level; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors

2017
Preparation, characterization and pharmacokinetics of cyadox nanosuspension.
    Scientific reports, 2017, 05-23, Volume: 7, Issue:1

    Topics: Animals; Biological Availability; Dogs; Drug Compounding; Drug Stability; Female; Male; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Povidone; Quinoxalines; Solubility; Suspensions

2017
Dietary exposure assessment of cyadox based on tissue depletion of cyadox and its major metabolites in pigs, chickens, and carp.
    Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:1

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Carps; Chickens; Dietary Supplements; Kidney; Liver; Muscle, Skeletal; Quinoxalines; Swine

2018
Differentially expressed genes in response to cyadox in swine liver analyzed by DDRT-PCR.
    Research in veterinary science, 2018, Volume: 118

    Topics: Animals; Blotting, Northern; Gene Expression Profiling; Liver; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; Swine

2018
Determination of olaquindox, carbadox and cyadox in animal feeds by ultra-performance liquid chromatography tandem mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2018, Volume: 35, Issue:7

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Carbadox; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Quinoxalines; Solid Phase Extraction; Tandem Mass Spectrometry

2018
Alleviative effect of some phytochemicals on cyadox-induced oxidative damage in rabbit erythrocytes.
    The Japanese journal of veterinary research, 2016, Volume: 64, Issue:3

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Oxidative Stress; Phytochemicals; Quinoxalines; Rabbits

2016
Synthesis of tritium-labeled cyadox, a promising antimicrobial growth-promoting agent with high specific activity.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2018, Volume: 139

    Topics: Animals; Animals, Domestic; Anti-Infective Agents; Growth Substances; Mass Spectrometry; Quinoxalines; Tritium

2018
N-O Reduction and ROS-Mediated AKT/FOXO1 and AKT/P53 Pathways Are Involved in Growth Promotion and Cytotoxicity of Cyadox.
    Chemical research in toxicology, 2018, 11-19, Volume: 31, Issue:11

    Topics: Apoptosis; Cell Line; Cell Survival; Epidermal Growth Factor; Forkhead Box Protein O1; Humans; Nitrogen; Oxidation-Reduction; Oxygen; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinoxalines; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53

2018
Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; NF-kappa B; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinoxalines; RNA Recognition Motif Proteins; RNA, Messenger; Signal Transduction; Smad Proteins; STAT Transcription Factors; Swine; Transforming Growth Factor beta; Zinc Fingers

2018
Pharmacokinetic-pharmacodynamic modeling of cyadox against Escherichia coli in swine.
    Microbial pathogenesis, 2019, Volume: 135

    Topics: Animals; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Female; Ileum; Male; Microbial Sensitivity Tests; Models, Biological; Quinoxalines; Swine; Swine Diseases

2019
Transcriptional regulation of seven cyadox-related genes mainly activated by PI3K and NF-кB signaling pathways in PK-15 cells.
    Research in veterinary science, 2020, Volume: 131

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Epidermal Growth Factor; Gene Expression Regulation; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinoxalines; Signal Transduction; Swine; Transcription, Genetic

2020
Dosage Regimen Formulation and Therapeutic Effect Evaluation of Cyadox Nanosuspension Against Dairy Cow Mastitis Caused by Staphylococcus aureus.
    Current drug delivery, 2021, Volume: 18, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cattle; Female; Humans; Mastitis; Microbial Sensitivity Tests; Quinoxalines; Staphylococcal Infections; Staphylococcus aureus

2021
Pharmacokinetics of cyadox and its main metabolites in rats, pigs, chickens, and carps following oral administration at three dosage.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 124

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Carps; Chickens; Female; Male; Quinoxalines; Rats; Species Specificity; Sus scrofa; Veterinary Drugs

2021
Acute and subchronic exposure of cyadox induced metabolic and transcriptomic disturbances in Wistar rats.
    Toxicology, 2022, Volume: 482

    Topics: Animals; Metabolomics; Quinoxalines; Rats; Rats, Wistar; Transcriptome

2022