quinoxalines has been researched along with cyadox in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (17.86) | 18.7374 |
| 1990's | 3 (5.36) | 18.2507 |
| 2000's | 8 (14.29) | 29.6817 |
| 2010's | 30 (53.57) | 24.3611 |
| 2020's | 5 (8.93) | 2.80 |
| Authors | Studies |
|---|---|
| de Graaf, GJ; Jager, LP; Nabuurs, MJ; van der Molen, EJ | 1 |
| Tokosová, M | 3 |
| Bakri, A; Beyersbergen van Henegouwen, GM; Bojarski, J; de Vries, H; Donker, AA | 1 |
| Baars, AJ; de Graaf, GJ; Jager, LP; van der Molen, EJ | 1 |
| Pleva, J; Tokosová, M | 1 |
| De Graaf, GJ; Spierenburg, TJ | 1 |
| Szabová, E | 1 |
| Cihák, R; Vontorková, M | 1 |
| Dvorák, M | 1 |
| Gandalovicová, D; Marhan, O; Sýkora, I | 1 |
| Cihák, R; Srb, V | 1 |
| Fang, G; He, Q; Wang, D; Yuan, Z; Zhang, Y; Zhou, S | 1 |
| Chen, D; Huang, L; Tao, Y; Wang, Y; Yuan, Z; Zhang, Y | 1 |
| Chen, D; Fan, S; Huang, L; Tao, Y; Wang, Y; Yuan, Z; Zhang, Y | 1 |
| Fan, S; Fang, G; He, Q; Wang, D; Wang, Y; Wei, Z; Yuan, Z; Zhou, S | 1 |
| Ding, MX; Fan, SX; Wang, YL; Yuan, ZH; Zhu, HL | 1 |
| Ding, MX; Wang, YL; Yuan, ZH; Zhu, HL | 1 |
| Chen, D; Huang, L; Tao, Y; Wang, Y; Yuan, Z | 1 |
| Chen, D; Dai, M; Huang, L; Liu, Z; Tao, Y; Wang, Y; Yuan, Z | 1 |
| Huang, LL; Huang, XJ; Liu, Y; Wang, X; Yan, CX; Yuan, ZH; Zhang, HH; Zhang, LY | 1 |
| He, QH; Huang, LL; Ihsan, A; Liu, ZL; Su, SJ; Wang, X; Wang, YL; Yuan, ZH; Zhou, W | 1 |
| Fang, GJ; Huang, LL; Ihsan, A; Liu, ZL; Wang, X; Wang, YL; Yuan, ZH; Zhou, W | 1 |
| Fang, B; He, L; Liu, K; Liu, Y; Su, Y; Zeng, Z; Zhang, G; Zhang, J | 1 |
| Deng, Y; Jiang, J; Ouyang, M; Tang, X; Wang, J; Zheng, M | 1 |
| Chen, D; Huang, L; Liu, Z; Pan, Y; Peng, D; Tao, Y; Wang, X; Wang, Y; Xu, N; Yuan, Zh | 1 |
| Dai, M; Guo, W; Hao, H; Huang, L; Liu, Z; Peng, D; Sun, Y; Wang, H; Wang, X; Wang, Y; Yao, M; Yuan, Z | 1 |
| Huang, C; Lei, H; Tang, H; Wang, Y; Zhao, X | 1 |
| Liu, ZY; Sun, ZL | 1 |
| Cheng, G; Huang, L; Ihsan, A; Iqbal, Z; Liu, Z; Pan, Y; Tan, Z; Tu, H; Wang, X; Wang, Y; Yuan, Z; Zhang, W; Zhang, Y | 1 |
| Cheng, G; Dai, M; Guo, W; Hao, H; Huang, L; Iqbal, Z; Liu, Z; Peng, D; Wang, X; Wang, Y; Yuan, Z | 1 |
| Chen, C; Cheng, G; Dai, M; Hao, H; Huang, L; Liu, Z; Wang, X; Yuan, Z | 1 |
| Ding, H; Fang, B; Gu, X; Li, Y; Yang, F; Zeng, Z; Zhang, B; Zhao, N | 1 |
| Dongmei, C; Harnud, S; Lingli, H; Ning, X; Yanfei, T; Yuanhu, P; Zhenli, L; Zonghui, Y | 1 |
| Cheng, G; Dai, M; Hao, H; Li, B; Liang, G; Liu, Z; Wang, C; Wang, X; Wang, Y; Weng, Z; Yuan, Z; Zhang, H | 1 |
| Chen, D; Cheng, G; Hao, H; Ihsan, A; Liu, Z; Wang, X; Wang, Y; Yuan, Z; Zhou, W | 1 |
| Gehring, R; Huang, L; Lin, Z; Riviere, JE; Yuan, Z; Zhou, X; Zhu, M | 1 |
| Chen, D; Cheng, G; Guo, P; Hao, H; Huang, Q; Ihsan, A; Jamil, F; Luo, X; Tao, Y; Wang, X; Yuan, Z | 1 |
| Chen, D; Cheng, G; Dai, M; Guo, P; Ihsan, A; Liu, Z; Luo, X; Wang, X; Yang, C; Yuan, Z | 1 |
| Alagawany, M; Farag, MR; Tufarelli, V | 1 |
| Awais, I; Cui, L; Dai, M; Lei, Z; Liu, Q; Wang, X; Yuan, Z; Zhang, J | 1 |
| Chen, D; Huang, L; Jiang, L; Liu, Z; Pan, Y; Sattar, A; Tao, Y; Xie, S; Yuan, Z | 1 |
| Huang, LL; Li, J; Pan, YH; Qiu, YM; Sun, LL; Wang, YL; Yuan, ZH | 1 |
| Cheng, G; Cui, L; Dai, M; Liu, Z; Lu, Q; Wang, X; Wang, Y; Yu, R; Yuan, Z; Zhang, Y | 1 |
| Li, H; Miao, X; Xu, L; Yang, Z | 1 |
| Alagawany, M; El-Hack, MEA; Farag, MR; Tufarelli, V | 1 |
| Harnud, S; Yuan, Z; Zhang, A | 1 |
| Dai, M; Lei, Z; Liu, Q; Liu, S; Sun, Q; Wang, X; Yu, H; Yuan, Z; Zhou, K | 1 |
| Cheng, G; Cui, L; Dai, M; Hao, H; Huang, D; Huang, L; Li, D; Liu, Z; Lu, Q; Peng, D; Wang, X; Wang, Y; Xing, D; Yuan, Z | 1 |
| Bakr Shabbir, MA; Dai, M; Huang, L; Maan, MK; Xu, D; Yuan, Z | 1 |
| Chen, D; Hafeez, MA; Huang, L; Sattar, A; Shabbir, MAB; Tahir, AH; Wu, Q; Xie, S; Yuan, Z | 1 |
| Cheng, G; Cui, L; Dai, M; Guo, J; Liu, Z; Lu, Q; Wang, X; Wang, Y; Zhao, H | 1 |
| Chen, D; Liu, S; Liu, Z; Meng, K; Pan, Y; Qu, W; Xie, S; Yue, T | 1 |
| Fu, S; Harnud, S; Huang, L; Pan, Y; Wang, Y; Zhang, A | 1 |
| Huang, C; Lei, H; Liu, C; Wang, Y | 1 |
1 review(s) available for quinoxalines and cyadox
| Article | Year |
|---|---|
The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.
Topics: Animals; Carbadox; Humans; Quinoxalines | 2013 |
3 trial(s) available for quinoxalines and cyadox
| Article | Year |
|---|---|
Effects of cyadox and olaquindox on intestinal mucosal immunity and on fecal shedding of Escherichia coli in piglets.
Topics: Animals; Escherichia coli; Feces; Immunity, Mucosal; Immunologic Factors; Intestinal Mucosa; Male; Quinoxalines; Swine | 2006 |
Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration.
Topics: Animals; Biomarkers; Biotransformation; China; Chromatography, High Pressure Liquid; Crosses, Genetic; Drug Residues; Food Additives; Food Contamination; Food Inspection; Kidney; Male; Meat; Quinoxalines; Sus scrofa; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Disposition of cyadox in domesticated cats following oral, intramuscular, and intravenous administration.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Cats; Cross-Over Studies; Feces; Female; Half-Life; Injections, Intramuscular; Male; Quinoxalines | 2020 |
52 other study(ies) available for quinoxalines and cyadox
| Article | Year |
|---|---|
Clinical signs and performance of pigs treated with different doses of carbadox, cyadox and olaquindox.
Topics: Animals; Anti-Bacterial Agents; Carbadox; Female; Hematocrit; Male; Quinoxalines; Swine; Weight Gain | 1990 |
[The effect of cyadox and virginiamycin on Marek's disease in chickens].
Topics: Animals; Anti-Bacterial Agents; Chickens; Marek Disease; Poultry Diseases; Quinoxalines; Virginiamycin | 1990 |
Photochemical reactions of quindoxin, olaquindox, carbadox and cyadox with protein, indicating photoallergic properties.
Topics: Animals; Anti-Bacterial Agents; Carbadox; Chemical Phenomena; Chemistry; Humans; Organophosphorus Compounds; Photochemistry; Photosensitivity Disorders; Proteins; Quinoxalines; Serum Albumin; Ultraviolet Rays | 1990 |
[The effect of growth stimulators on the levels of various macroelements in chickens].
Topics: Animals; Anti-Bacterial Agents; Chickens; Electrolytes; Growth Substances; Nitrovin; Quinoxalines; Tissue Distribution; Virginiamycin | 1989 |
[The effect of growth stimulators on the levels of various trace elements in chickens].
Topics: Animals; Anti-Bacterial Agents; Chickens; Growth Substances; Nitrovin; Quinoxalines; Tissue Distribution; Trace Elements; Virginiamycin | 1989 |
Comparative study of the effect of the effect of carbadox, olaquindox and cyadox on aldosterone, sodium and potassium plasma levels in weaned pigs.
Topics: Aldosterone; Animal Feed; Animals; Anti-Bacterial Agents; Carbadox; Female; Male; Potassium; Quinoxalines; Sodium; Swine | 1989 |
[The effect of growth stimulators on the health status and growth of broilers].
Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Chickens; Growth Substances; Nitrofurans; Nitrovin; Quinoxalines | 1988 |
Liquid chromatographic determination of cyadox in medicated feeds and in the contents of the porcine gastrointestinal tract with fluorescence detection.
Topics: Animal Feed; Animals; Duodenum; Food Additives; Gastrointestinal Contents; Quinoxalines; Spectrometry, Fluorescence; Swine | 1988 |
[Cytogenetic effects of non-antibiotic growth stimulators on bone marrow cells in mice].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbadox; Chromosome Aberrations; Growth Substances; Male; Mice; Mice, Inbred ICR; Quinoxalines | 1988 |
Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. III. Transplacental micronucleus test in mice.
Topics: Administration, Oral; Animals; Bone Marrow; Carbadox; Cell Nucleus; Female; Fetus; Injections, Intraperitoneal; Liver; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy; Quinoxalines | 1985 |
[Increasing the effectiveness of feed mixtures for the early weaning of piglets with the addition of fats or growth stimulators].
Topics: Animal Feed; Animals; Dietary Fats; Growth Substances; Quinoxalines; Swine; Weaning | 1984 |
[The effect of the non-antibiotic growth stimulators, Carbadox and Cyadox, on reproduction in laboratory animals].
Topics: Animals; Carbadox; Female; Fertility; Fetal Death; Fetus; Growth Substances; Male; Pregnancy; Pregnancy, Animal; Quinoxalines; Rats; Spermatogenesis | 1981 |
Cytogenetic effects of quinoxaline-1,4-dioxide-type growth-promoting agents. I. Micronucleus test in rats.
Topics: Animals; Anti-Bacterial Agents; Bone Marrow; Carbadox; Cell Nucleus; Erythrocytes; Male; Mutagenicity Tests; Mutagens; Mutation; Quinoxalines; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1983 |
Subchronic oral toxicity study with cyadox in Wistar rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Body Weight; Diet; Dose-Response Relationship, Drug; Epithelial Cells; Female; Hepatocytes; Kidney Tubules, Proximal; Male; No-Observed-Adverse-Effect Level; Quinoxalines; Rats; Rats, Wistar | 2006 |
Effects of cooking and storage on residues of cyadox in chicken muscle.
Topics: Animals; Chickens; Cooking; Drug Residues; Drug Stability; Food Preservation; Half-Life; Hot Temperature; Muscles; Quinoxalines | 2005 |
Development of HPLC methods for the determination of cyadox and its main metabolites in goat tissues.
Topics: Animals; Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Goats; Quinoxalines; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Experimental evaluation of cyadox phototoxicity to Balb/c mouse skin.
Topics: Animals; Dose-Response Relationship, Drug; Erythema; Mice; Mice, Inbred BALB C; Quinoxalines; Skin; Ultraviolet Rays | 2006 |
Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunity of piglets orally inoculated with Escherichia coli.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Energy Intake; Escherichia coli; Immunoglobulin A; Intestinal Mucosa; Lymphocyte Count; Quinoxalines; Random Allocation; Swine; Weight Gain | 2006 |
Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken.
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Fats; Kidney; Liver; Molecular Structure; Muscles; Quinoxalines; Reproducibility of Results | 2008 |
Metabolism of cyadox in rat, chicken and pig liver microsomes and identification of metabolites by accurate mass measurements using electrospray ionization hybrid ion trap/time-of-flight mass spectrometry.
Topics: Animals; Biotransformation; Chickens; Chromatography, High Pressure Liquid; Growth Substances; Male; Microsomes, Liver; Quinoxalines; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Swine | 2009 |
ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro.
Topics: Adrenal Cortex; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Mitochondria; Molecular Structure; Oxidation-Reduction; Quinoxalines; Reactive Oxygen Species; Swine; Time Factors | 2010 |
A chronic toxicity study of cyadox in Wistar rats.
Topics: Animals; Body Weight; Eating; Female; Kidney; Liver; Male; No-Observed-Adverse-Effect Level; Organ Size; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Toxicity Tests, Chronic; Transaminases | 2011 |
Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epididymis; Female; Fetal Development; Male; Maternal Exposure; No-Observed-Adverse-Effect Level; Organ Size; Pregnancy; Quinoxalines; Rats; Rats, Wistar; Reproduction; Teratogens; Testis | 2011 |
Simultaneous determination of cyadox and its metabolites in plasma by high-performance liquid chromatography tandem mass spectrometry.
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Molecular Structure; Quinoxalines; Tandem Mass Spectrometry | 2011 |
The mechanism of enzymatic and non-enzymatic N-oxide reductive metabolism of cyadox in pig liver.
Topics: Animals; Catalase; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytosol; Hemeproteins; Liver; Microsomes, Liver; Oxidation-Reduction; Oxides; Quinoxalines; Recombinant Proteins; Sus scrofa | 2011 |
Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry.
Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Colon; Hydrolysis; Ileum; Intestinal Mucosa; Male; Mass Spectrometry; Microsomes; Oxidation-Reduction; Quinoxalines; Swine | 2011 |
Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.
Topics: Animals; Anti-Bacterial Agents; Base Sequence; DNA Primers; DNA, Complementary; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Glycolysis; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Nucleic Acid Hybridization; Oxides; Phenotype; Phosphorylation; Polymerase Chain Reaction; Quinoxalines; Swine | 2012 |
Metabolic influence of acute cyadox exposure on Kunming mice.
Topics: Amino Acids; Animals; Dimethylamines; Food Safety; Hippurates; Kidney Medulla; Liver; Methylamines; Mice; Nucleotides; Quinoxalines | 2013 |
Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.
Topics: Animals; Anti-Infective Agents; Bone Marrow Cells; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; DNA Replication; Dose-Response Relationship, Drug; Humans; Lymphocytes; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Mutagens; Mutation; Quinoxalines; Random Allocation; Salmonella typhimurium | 2013 |
Impact of cyadox on human colonic microflora in chemostat models.
Topics: Anti-Infective Agents; Bacteroides fragilis; Bifidobacterium; Colon; Drug Resistance, Bacterial; Enterococcus; Escherichia coli; Feces; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Models, Biological; No-Observed-Adverse-Effect Level; Quinoxalines; Salmonella typhimurium; Veterinary Drugs | 2013 |
Mechanism of porcine liver xanthine oxidoreductase mediated N-oxide reduction of cyadox as revealed by docking and mutagenesis studies.
Topics: Animals; Binding Sites; Cloning, Molecular; Enzyme Activation; Gene Expression; Kinetics; Liver; Male; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Protein Conformation; Quinoxalines; Recombinant Proteins; Swine; Xanthine Dehydrogenase | 2013 |
Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats.
Topics: Animals; Anti-Infective Agents; Biological Transport; Carps; Chickens; Drug Residues; Female; Food Contamination; Food Safety; Kidney; Liver; Male; Meat; Molecular Structure; Muscles; Quinoxalines; Rats; Rats, Wistar; Swine; Tissue Distribution | 2015 |
Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.
Topics: Anti-Bacterial Agents; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Annotation; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Proteomics; Quinoxalines; Reactive Oxygen Species; SOS Response, Genetics; Structure-Activity Relationship; Tirapazamine; Triazines | 2015 |
Assessment of thirteen-week subchronic oral toxicity of cyadox in Beagle dogs.
Topics: Administration, Oral; Animals; Body Weight; Dogs; Eating; Female; Male; No-Observed-Adverse-Effect Level; Organ Size; Quinoxalines; Time Factors; Toxicity Tests, Subchronic | 2015 |
Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modelling.
Topics: Adipose Tissue; Animal Feed; Animals; Anti-Infective Agents; Biotransformation; Chromatography, Liquid; Drug Residues; Food Analysis; Kidney; Liver; Models, Statistical; Monte Carlo Method; Muscle, Skeletal; Quinoxalines; Swine; Tandem Mass Spectrometry; Veterinary Drugs | 2015 |
Evaluation of the safety of primary metabolites of cyadox: Acute and sub-chronic toxicology studies and genotoxicity assessment.
Topics: Animals; Anti-Infective Agents; Biomarkers; Biotransformation; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Liver; Male; Maximum Tolerated Dose; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Organ Size; Quinoxalines; Rats, Wistar; Risk Assessment; Time Factors; Toxicity Tests, Acute; Toxicity Tests, Subchronic; Weight Loss | 2016 |
High risk of adrenal toxicity of N1-desoxy quinoxaline 1,4-dioxide derivatives and the protection of oligomeric proanthocyanidins (OPC) in the inhibition of the expression of aldosterone synthetase in H295R cells.
Topics: Adrenal Gland Diseases; Aldosterone; Antioxidants; Biotransformation; Cell Line; Cell Survival; Cytochrome P-450 CYP11B2; Humans; Oxidative Stress; Proanthocyanidins; Quinoxalines; RNA, Messenger; Steroid 11-beta-Hydroxylase | 2016 |
In vitro antioxidant activities of resveratrol, cinnamaldehyde and their synergistic effect against cyadox-induced cytotoxicity in rabbit erythrocytes.
Topics: Acrolein; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cytoprotection; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Enzymes; Eryptosis; Erythrocytes; Glutathione; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Picrates; Protein Carbonylation; Quinoxalines; Rabbits; Resveratrol; Stilbenes | 2017 |
A two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats.
Topics: Animals; Anti-Infective Agents; Carcinogenicity Tests; Diet; Female; Male; No-Observed-Adverse-Effect Level; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2017 |
Preparation, characterization and pharmacokinetics of cyadox nanosuspension.
Topics: Animals; Biological Availability; Dogs; Drug Compounding; Drug Stability; Female; Male; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Povidone; Quinoxalines; Solubility; Suspensions | 2017 |
Dietary exposure assessment of cyadox based on tissue depletion of cyadox and its major metabolites in pigs, chickens, and carp.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Carps; Chickens; Dietary Supplements; Kidney; Liver; Muscle, Skeletal; Quinoxalines; Swine | 2018 |
Differentially expressed genes in response to cyadox in swine liver analyzed by DDRT-PCR.
Topics: Animals; Blotting, Northern; Gene Expression Profiling; Liver; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; Swine | 2018 |
Determination of olaquindox, carbadox and cyadox in animal feeds by ultra-performance liquid chromatography tandem mass spectrometry.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Carbadox; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Quinoxalines; Solid Phase Extraction; Tandem Mass Spectrometry | 2018 |
Alleviative effect of some phytochemicals on cyadox-induced oxidative damage in rabbit erythrocytes.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Oxidative Stress; Phytochemicals; Quinoxalines; Rabbits | 2016 |
Synthesis of tritium-labeled cyadox, a promising antimicrobial growth-promoting agent with high specific activity.
Topics: Animals; Animals, Domestic; Anti-Infective Agents; Growth Substances; Mass Spectrometry; Quinoxalines; Tritium | 2018 |
N-O Reduction and ROS-Mediated AKT/FOXO1 and AKT/P53 Pathways Are Involved in Growth Promotion and Cytotoxicity of Cyadox.
Topics: Apoptosis; Cell Line; Cell Survival; Epidermal Growth Factor; Forkhead Box Protein O1; Humans; Nitrogen; Oxidation-Reduction; Oxygen; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinoxalines; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2018 |
Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; NF-kappa B; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinoxalines; RNA Recognition Motif Proteins; RNA, Messenger; Signal Transduction; Smad Proteins; STAT Transcription Factors; Swine; Transforming Growth Factor beta; Zinc Fingers | 2018 |
Pharmacokinetic-pharmacodynamic modeling of cyadox against Escherichia coli in swine.
Topics: Animals; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Female; Ileum; Male; Microbial Sensitivity Tests; Models, Biological; Quinoxalines; Swine; Swine Diseases | 2019 |
Transcriptional regulation of seven cyadox-related genes mainly activated by PI3K and NF-кB signaling pathways in PK-15 cells.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Epidermal Growth Factor; Gene Expression Regulation; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinoxalines; Signal Transduction; Swine; Transcription, Genetic | 2020 |
Dosage Regimen Formulation and Therapeutic Effect Evaluation of Cyadox Nanosuspension Against Dairy Cow Mastitis Caused by Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Cattle; Female; Humans; Mastitis; Microbial Sensitivity Tests; Quinoxalines; Staphylococcal Infections; Staphylococcus aureus | 2021 |
Pharmacokinetics of cyadox and its main metabolites in rats, pigs, chickens, and carps following oral administration at three dosage.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Carps; Chickens; Female; Male; Quinoxalines; Rats; Species Specificity; Sus scrofa; Veterinary Drugs | 2021 |
Acute and subchronic exposure of cyadox induced metabolic and transcriptomic disturbances in Wistar rats.
Topics: Animals; Metabolomics; Quinoxalines; Rats; Rats, Wistar; Transcriptome | 2022 |