quinoxalines has been researched along with clonidine in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (18.13) | 18.7374 |
| 1990's | 90 (49.45) | 18.2507 |
| 2000's | 43 (23.63) | 29.6817 |
| 2010's | 16 (8.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barturen, F; García-Sevilla, JA; Meana, JJ | 1 |
| Barturen, F; Gabilondo, AM; García-Sevilla, JA; Meana, JJ | 1 |
| Blandford, DE; Li, P; Penner, SB; Smyth, DD | 1 |
| Okuma, Y; Reisine, T | 1 |
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Akbarali, H; Horstman, DA; Limbird, LE; Surprenant, A | 1 |
| Berridge, TL; Doxey, JC; Roach, AG; Smith, CF | 1 |
| Jansen van't Land, C; van der Laan, JW | 1 |
| Ball, SG; Ong, ML; Vaughan, PF | 1 |
| Agneter, E; Drobny, H; Singer, EA | 1 |
| Fitzgerald, RD; Harris, GC | 1 |
| Halliday, CA; Jones, BJ; Skingle, M; Tyers, MB; Walsh, DM; Wise, H | 1 |
| Andersson, RG; Grundström, N; Jacobsson, L | 1 |
| Ruff, G; Rump, LC; Schollmeyer, P; Wolk, V | 1 |
| Andreasen, M; Lambert, JD | 1 |
| Schwietert, HR; van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Boehm, S; Huck, S | 1 |
| Gleason, MM; Hieble, JP | 1 |
| Benishin, C; Fredholm, BB; Hu, PS | 1 |
| del Arco, C; del Olmo, E; Díaz, A; González, AM; Pascual, J; Pazos, A | 1 |
| Conway, S; Krulich, L; Mauceri, H; Moherek, R; Richardson, L; Speciale, S | 1 |
| Osborne, NN | 1 |
| Carpéné, C; Galitzky, J; Lafontan, M; Saulnier-Blache, JS | 1 |
| Chien, DS; Gluchowski, C; Homsy, JJ; Tang-Liu, DD | 1 |
| Giudicelli, Y; Leneveu, MC; Pecquery, R | 1 |
| Hill, SJ; Straw, RM | 1 |
| García-Sáinz, JA; Martínez, OM | 1 |
| Bill, DJ; Hughes, IE; Stephens, RJ | 1 |
| Galitzky, J; Paris, H; Senard, JM | 1 |
| Berlan, M; Galitzky, J; Lafontan, M; Paris, H | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Carpéné, C; Lafontan, M; Langin, D; Saulnier-Blache, JS | 1 |
| Berlan, M; Lafontan, M; Montastruc, P; Taouis, M | 1 |
| Hinton, CF; White, JF | 1 |
| Akasu, T; Nishimura, T; Tokimasa, T; Tsurusaki, M | 1 |
| Honda, K; Miyata-Osawa, A; Shiono, K; Takenaka, T; Terai, M | 1 |
| Horng, JS; Messick, K; Ruffolo, RR | 1 |
| Lattimer, N; Rhodes, KF | 1 |
| Bylund, DB; Ray-Prenger, C; Turner, JT | 1 |
| Brasier, RS; Gantzos, RD; Neubig, RR | 1 |
| Berlan, M; Lafontan, M; Taouis, M | 1 |
| Bond, RA; Charlton, KG; Clarke, DE | 1 |
| Convents, A; Convents, D; De Backer, JP; Vauquelin, G | 1 |
| Nyman, L; Saano, V; Savola, JM; Virtanen, R | 1 |
| North, RA; Surprenant, A | 1 |
| Carpéné, C; Lavau, M; Rebourcet, MC | 1 |
| Messick, K; Ruffolo, RR | 1 |
| Davies, SL; Hale, AS; Horton, RW; Katona, CL; Kelly, JS; Paykel, ES; Theodorou, AE; Yamaguchi, Y | 1 |
| Kassarich, J; Lien, EL; Morrison, A; Sullivan, D | 1 |
| Denis, C; Murat, JC; Paris, H | 1 |
| Fähndrich, E; Haug, HJ; Rommelspacher, H; Strauss, S | 1 |
| Fernandez-Roman, M; Fuentes, JA; Naranjo, JR; Urdin, MC | 1 |
| Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG; Scatton, B | 1 |
| Cavero, I; Doxey, JC; Roach, AG; Strachan, DA | 1 |
| Kerry, R; Scrutton, MC | 1 |
| Shepperson, NB | 1 |
| Bogaert, MG; Lefebvre, RA; Verplanken, PA | 1 |
| Chou, B; Green, PG; Khasar, SG; Levine, JD | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Advenier, C; Biyah, K | 1 |
| Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG | 1 |
| Dalley, JW; Stanford, SC | 1 |
| Galligan, JJ | 1 |
| Debink, N; Gabelt, BT; Hubbard, WC; Kaufman, PL; Peterson, CM; Robinson, JC; Wadhwa, A | 1 |
| Ge, YZ; Morrison, SF | 1 |
| Hanmer, C; Kendall, DA; Mason, R; Millns, P; Pinthong, D; Wilson, VG; Wright, IK | 1 |
| Gazzola, C; Hunter, RA; Lisle, AT; Magner, T | 1 |
| Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Serle, JB | 1 |
| Allgaier, C; Belledin, M; Hertting, G; Jackisch, R; Schobert, A | 1 |
| García-Sevilla, JA; Garro, MA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L | 1 |
| Guimarães, S; Nunes, JP | 1 |
| Ferrell, WR; Najafipour, H | 1 |
| Robinson, NE; Wang, Z; Yu, M | 1 |
| Crepel, F; Hirsch, JC; Law-Tho, D | 1 |
| García-Sevilla, JA; Sastre, M | 1 |
| Bouloumié, A; Devedjian, JC; Lafontan, M; Planat, V; Record, M; Saulnier-Blache, JS; Valet, P | 1 |
| Faber, JE; Tateishi, J | 1 |
| Angel, I; Grosset, A; Langer, SZ; Perrault, G; Schoemaker, H | 1 |
| Nott, MW; Rand, MJ; Thaina, P | 2 |
| Asier Garro, M; García-Sevilla, JA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L | 1 |
| Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 2 |
| Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
| Intengan, HD; Smyth, DD | 1 |
| Coupar, IM; Liu, L | 2 |
| Colpaert, F; Marien, M; Tellez, S | 1 |
| Ingram, S; McCleskey, EW; Wilding, TJ; Williams, JT | 1 |
| Garst, ME; Macdonald, TL; Munk, SA; Thompson, CD; Wiese, A | 1 |
| Agneter, E; Feuerstein, TJ; Sauermann, W; Singer, EA | 1 |
| Guimarães, S; Paiva, MQ; Pereira, O | 1 |
| Arnsten, AF; Jentsch, DJ; Li, BM; Steere, JC | 1 |
| Garrison, PM; Stewart, WC | 1 |
| Callado, LF; García-Sevilla, JA; Grijalba, B; Meana, JJ; Pazos, A; Sastre, M | 1 |
| Abysique, A; Bouvier, M; Orsoni, P | 1 |
| Ohia, SE; Opere, CA | 1 |
| Crichton, AC | 1 |
| Gramer, E | 1 |
| Ali, A; Cheng, HY; Ting, KN; Wilson, VG | 1 |
| Blier, P; de Montigny, C; Mongeau, R; Weiss, M | 1 |
| Buerkle, H; Yaksh, TL | 1 |
| Brubaker, RF; Maus, TL; Nau, CB; Schadlu, R | 1 |
| García-Barrado, MJ; Moratinos, J; Palomero, J; Sancho, C | 1 |
| Gordon, RN; Greenfield, DS; Lama, P; Liebmann, JM; Ritch, R | 1 |
| Hoyng, PF; Rasker, MT | 1 |
| Schwartz, M; Wheeler, LA; Yoles, E | 1 |
| Chopin, P; Colpaert, FC; Marien, M | 1 |
| Bahia, DS; Jackson, VN; Milligan, G | 1 |
| Boles Carenini, B; Brogliatti, B; Lo Presti, L; Morgese, A; Ravot, M | 1 |
| Gebhardt, DO | 1 |
| Assalian, A; Chevrier, RL; Duperré, J; Lesk, MR | 1 |
| Burnstein, Y; Robin, AL | 1 |
| Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T | 1 |
| Brubaker, RF; Maus, TL; Nau, C | 1 |
| Kaufman, PF | 1 |
| Cha, SC; Glover, BK; Kim, C; Kim, YY; Nguyen, KD; Shin, DH | 1 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Mateo, Y; Meana, JJ | 1 |
| Barnes, SD; Campagna, JA; Dirks, MS; Doe, EA | 1 |
| Pihlavisto, M; Scheinin, M | 1 |
| Apătăchioae, I; Chiseliţă, D | 1 |
| Kitazawa, T; Maezono, Y; Taneike, T | 1 |
| Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS | 1 |
| Díaz-Cabiale, Z; Fuxe, K; Narváez, JA; Petersson, M; Uvnäs-Moberg, K | 1 |
| Gross, RL; Orengo-Nania, S; Williams, GC | 1 |
| Borges, AC; Fauaz, G; Feres, T; Paiva, TB | 1 |
| Colpaert, FC; Pauwels, PJ | 1 |
| Gyermek, L; Hanaoka, K; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T | 1 |
| Busquets, X; García-Sevilla, JA; Miralles, A; Ribas, C | 1 |
| Ang, RT; Chen, TC; Fan, JT; Grosskreutz, CL; Pasquale, LR | 1 |
| Hillier, C; Jarajapu, YP; MacDonald, A | 1 |
| Burke, JA; Nieves, AL; Spada, CS; Wheeler, LA; Woodward, DF | 1 |
| Simonsen, U; Wikberg-Matsson, A | 1 |
| Chao, HM; Osborne, NN | 1 |
| Adler-Graschinsky, E; Boric, MP; Figueroa, XF; Huidobro-Toro, JP; Mendizábal, VE; Poblete, MI | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Parvez, H | 1 |
| Dikranian, K; Farber, NB; Heinkel, C; Jiang, XP; Kim, SH | 1 |
| Bishai, JM; Buchholz, JN; Gheorghe, CP; Longo, LD; Meulenaar, R; Nijland, R; Penninga, L; Zhang, L; Zhao, Y | 1 |
| García-Barrado, MJ; Iglesias-Osma, MC; Martín, M; Moratinos, J; Rodríguez, R | 1 |
| Ciancaglini, M; Costagliola, C; D'Oronzo, E; Mastropasqua, L; Parmeggiani, F; Sebastiani, A | 1 |
| Ikeda, M; Lipski, J; Matsumoto, S; Takeda, M; Tanimoto, T | 1 |
| Artigues-Varin, C; Mulder, P; Richard, V; Thuillez, C; Varin, R | 1 |
| Nishio, I; Tsuda, K; Tsuda, S | 1 |
| Eglen, RM; Kendall, DA; Maclennan, SJ; Pinthong, D; Wilson, VG | 1 |
| Foehring, RC; Geisert, E; Lorenzon, NM; Stewart, AE; Timmons, SD | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Kallio, J; Olli-Lähdesmäki, T; Scheinin, M; Tiger, M; Vainio, M | 1 |
| Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
| Ignatowski, TA; Reynolds, JL; Spengler, RN; Sud, R | 1 |
| Angeli, P; Buccioni, M; Giardinà, D; Gulini, U; Marucci, G; Melchiorre, C; Sagratini, G; Testa, R | 1 |
| Chen, TC | 1 |
| Corelli, RL; Hudmon, KS | 1 |
| Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
| Castillo, C; Castillo, EF; López, RM; Ortíz, CS; Ruíz, A; Vélez, JM | 1 |
| Ignatowski, TA; Knight, PR; Spengler, RN; Sud, R | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Frishman, WH | 1 |
| Fuchsjäger-Mayrl, G; Garhofer, G; Resch, H; Schmetterer, L; Weigert, G | 1 |
| Pulges, O; Rinken, A | 1 |
| Chen, W; Marvizón, JC; Song, B | 1 |
| Brawek, B; Feuerstein, TJ; Hoeren, M; Löffler, M; Mantovani, M; Steffens, M; van Velthoven, V | 1 |
| Cheevers, CV; Donello, JE; Gil, DW; Kedzie, KM; Manlapaz, CA; Rao, S; Tang, E | 1 |
| Bailly, M; Cosgrave, E; Dahlmann-Noor, AH; Lowe, S; Vivian, AJ | 1 |
| Bau, CH; Bizarro, L; Dobler, CJ; Kortmann, GL | 1 |
| Deissenrieder, F; Groneberg, D; Kusma, B; Mache, S; Quarcoo, D; Welte, T | 1 |
| Bylund, DB; Montgomery, MD | 1 |
| Bhat, A; Crain, D | 1 |
| Dermon, C; Panagis, L; Prokosch, V; Thanos, S; Volk, GF | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Besada, E; Hardigan, P; Najman, P; Reed, K; Shechtman, D | 1 |
| Belcon, AL | 1 |
| Aston-Jones, G; Smith, RJ | 1 |
| Alba-Delgado, C; Berrocoso, E; Borges, G; Horrillo, I; Meana, JJ; Mico, JA; Neto, F; Ortega, JE; Sánchez-Blázquez, P | 1 |
| Arencibia-Albite, F; Figueroa, J; Jiménez-Rivera, CA; Schwarz, D; Vázquez-Torres, R; Velásquez-Martinez, MC; Vélez-Hernandez, ME | 1 |
| Aono, Y; Cools, AR; Koshikawa, N; Saigusa, T; Takada, K; Uchida, T; Verheij, MM | 1 |
| Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B | 1 |
| Bernabé Barrios, MJ; Rodríguez Hermosa, JL; Santamaría Rodríguez, B; Zamarro García, C | 1 |
| Fairbanks, CA; Kitto, KF; Messing, RO; Overland, AC; Schuster, DJ; Stone, LS; Wilcox, GL | 1 |
| Ebbert, JO; Elrashidi, MY | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
11 review(s) available for quinoxalines and clonidine
| Article | Year |
|---|---|
Pharmacological advances in the treatment of glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Ethacrynic Acid; Glaucoma; Humans; Latanoprost; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1994 |
Beta-blocker-induced complications and the patient with glaucoma. Newer treatments to help reduce systemic adverse events.
Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Cardiovascular System; Central Nervous System; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Neurosecretory Systems; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Respiratory System; Sulfonamides; Thiophenes | 1998 |
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Female; Glaucoma; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1998 |
Selectivity of site of action and systemic effects of topical alpha agonists.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Optic Nerve; Quinoxalines; Treatment Outcome | 1998 |
Assessment of ocular hypotensive mechanisms and additivity of antiglaucoma drugs in humans.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Brimonidine Tartrate; Clonidine; Drug Synergism; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
[Alpha-2 adrenergic agonists in the treatment of glaucoma].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Brimonidine Tartrate; Clonidine; Glaucoma; Humans; Intraocular Pressure; Quinoxalines | 1999 |
Pharmacologic interventions for smoking cessation.
Topics: Administration, Cutaneous; Administration, Inhalation; Antidepressive Agents, Second-Generation; Benzazepines; Bupropion; Chewing Gum; Clonidine; Critical Care; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Nicotine; Nicotinic Agonists; Nortriptyline; Nurse's Role; Patient Education as Topic; Patient Selection; Phytotherapy; Piperidines; Pyrazoles; Quinoxalines; Rimonabant; Smoking Cessation; Smoking Prevention; United States; United States Food and Drug Administration; Varenicline | 2006 |
Smoking cessation pharmacotherapy--nicotine and non-nicotine preparations.
Topics: Administration, Cutaneous; Administration, Inhalation; Benzazepines; Bupropion; Chewing Gum; Clonidine; Coronary Artery Disease; Humans; Monoamine Oxidase Inhibitors; Nicotine; Nortriptyline; Piperidines; Pyrazoles; Quinoxalines; Receptors, Nicotinic; Rimonabant; Selective Serotonin Reuptake Inhibitors; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tobacco, Smokeless; Varenicline | 2007 |
Pharmacogenetics of smoking cessation therapy.
Topics: Benzazepines; Bupropion; Clonidine; Genome-Wide Association Study; Humans; Nicotine; Nortriptyline; Pharmacogenetics; Quinoxalines; Smoking Cessation; Varenicline | 2010 |
[Smoking in COPD].
Topics: Benzazepines; Bupropion; Clonidine; Comorbidity; Disease Progression; Europe; Humans; Motivation; Nicotinic Agonists; Nortriptyline; Prevalence; Pulmonary Disease, Chronic Obstructive; Quinoxalines; Severity of Illness Index; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder; Varenicline | 2011 |
Emerging drugs for the treatment of tobacco dependence: 2014 update.
Topics: Atomoxetine Hydrochloride; Benzazepines; Bupropion; Clinical Trials as Topic; Clonidine; Humans; Mecamylamine; Nicotine; Nortriptyline; Propylamines; Quinoxalines; Tobacco Use Cessation Devices; Tobacco Use Disorder; Varenicline | 2014 |
14 trial(s) available for quinoxalines and clonidine
| Article | Year |
|---|---|
Comparison of the efficacy of apraclonidine and brimonidine as aqueous suppressants in humans.
Topics: Adrenergic alpha-Agonists; Adult; Aqueous Humor; Brimonidine Tartrate; Clonidine; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Quinoxalines; Tonometry, Ocular | 1998 |
Lack of cross-reactive allergic response to brimonidine in patients with known apraclonidine allergy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Clonidine; Cross Reactions; Drug Hypersensitivity; Eye Diseases; Follow-Up Studies; Glaucoma; Humans; Middle Aged; Quinoxalines; Time Factors | 1998 |
Apraclonidine 0.5% versus brimonidine 0.2% for the control of intraocular pressure elevation following anterior segment laser procedures.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anterior Eye Segment; Brimonidine Tartrate; Chronic Disease; Clonidine; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Observer Variation; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Trabeculectomy; Treatment Outcome | 1999 |
Comparison of the early effects of brimonidine and apraclonidine as topical ocular hypotensive agents.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
Long-term brimonidine therapy in glaucoma patients with apraclonidine allergy.
Topics: Adrenergic alpha-Agonists; Aged; Brimonidine Tartrate; Chronic Disease; Clonidine; Drug Hypersensitivity; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines | 1999 |
Control of intraocular pressure elevations after argon laser trabeculoplasty: comparison of brimonidine 0.2% to apraclonidine 1.0%.
Topics: Adrenergic alpha-Agonists; Aged; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Trabeculectomy | 1999 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Blood Pressure; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Quinoxalines; Safety; Trabeculectomy | 2001 |
Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aged; Blood Pressure; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Visual Fields | 2002 |
Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Intraocular Pressure; Iridectomy; Laser Therapy; Lens Capsule, Crystalline; Male; Ocular Hypertension; Postoperative Complications; Quinoxalines; Trabeculectomy; Treatment Outcome; Visual Acuity | 2005 |
Effects of topical clonidine versus brimonidine on choroidal blood flow and intraocular pressure during squatting.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Blood Flow Velocity; Brimonidine Tartrate; Choroid; Clonidine; Cross-Over Studies; Double-Blind Method; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Posture; Quinoxalines; Regional Blood Flow; Tonometry, Ocular | 2007 |
Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery.
Topics: Adrenergic alpha-Agonists; Adult; Blood Loss, Surgical; Brimonidine Tartrate; Clonidine; Combined Modality Therapy; Conjunctiva; Humans; Middle Aged; Pilot Projects; Prospective Studies; Quinoxalines; Strabismus; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Humans; Male; Miotics; Photometry; Pupil; Quinoxalines; Young Adult | 2011 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
157 other study(ies) available for quinoxalines and clonidine
| Article | Year |
|---|---|
Alpha 2-adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Binding, Competitive; Brain; Brain Mapping; Brimonidine Tartrate; Clonidine; Depressive Disorder; Female; Humans; Male; Middle Aged; Quinoxalines; Radioligand Assay; Receptors, Adrenergic; Schizophrenia; Schizophrenic Psychology; Suicide; Violence | 1992 |
Acute ethanol intoxication may not alter alpha 2-adrenoceptors in the human brain.
Topics: Adrenergic alpha-Agonists; Adult; Alcoholic Intoxication; Brain; Brimonidine Tartrate; Clonidine; Female; Humans; Kinetics; Male; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha | 1992 |
Opposite rank order of potency for alpha-2 adrenoceptor agonists on water and solute excretion in the rat: two sites and/or receptors?
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Diuresis; Dose-Response Relationship, Drug; Infusions, Intra-Arterial; Kidney; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium | 1992 |
Immunoprecipitation of alpha 2a-adrenergic receptor-GTP-binding protein complexes using GTP-binding protein selective antisera. Changes in receptor/GTP-binding protein interaction following agonist binding.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Line; Clonidine; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Immune Sera; Iodine Radioisotopes; Precipitin Tests; Quinoxalines; Receptors, Adrenergic, alpha; Swine; Yohimbine | 1992 |
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents.
Topics: Adrenergic alpha-Agonists; Animals; Asparagine; Aspartic Acid; Brimonidine Tartrate; Calcium Channels; Cell Line; Clonidine; GTP-Binding Proteins; Membrane Potentials; Mutagenesis, Site-Directed; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Receptors, Somatostatin; Recombinant Proteins; Somatostatin; Transfection | 1992 |
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Blood Glucose; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Idazoxan; Imidazoles; Insulin; Male; Muscles; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1992 |
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Doxazosin; Drug Implants; Eating; Food; Male; Morphine; Morphine Dependence; Motor Activity; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Regulation of noradrenaline release from rat occipital cortex tissue chops by alpha 2-adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Brimonidine Tartrate; Bucladesine; Clonidine; Colforsin; Cyclic AMP; Histological Techniques; Male; Norepinephrine; Occipital Lobe; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Quinolines; Quinoxalines; Rats; Receptors, Adrenergic, alpha | 1991 |
Effects of centrally administered anxiolytic agents on classically conditioned bradycardia.
Topics: Animals; Anti-Anxiety Agents; Arousal; Brain; Brain Mapping; Brimonidine Tartrate; Clonidine; Conditioning, Classical; Corticotropin-Releasing Hormone; Enkephalin, Methionine; Heart Rate; Male; Peptide Fragments; Quinoxalines; Rats; Reflex, Startle | 1991 |
The pharmacology of fluparoxan: a selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Aorta; Body Temperature; Brimonidine Tartrate; Clonidine; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Piperoxan; Postural Balance; Pyrroles; Quinoxalines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Histamine; Receptors, Muscarinic; Receptors, Serotonin; Vas Deferens | 1991 |
Influence of some alpha 2-receptor agonists and antagonists on the excitatory non-adrenergic, non-cholinergic neurotransmission in the airways of guinea-pigs in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Quinoxalines; Respiratory Muscles; Respiratory System; Synaptic Transmission; Vagus Nerve | 1991 |
Alpha 2-adrenoceptor activation inhibits noradrenaline release in human and rabbit isolated renal arteries.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Animals; Brimonidine Tartrate; Clonidine; Female; Humans; In Vitro Techniques; Kidney; Male; Middle Aged; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Renal Artery; Sympathetic Nervous System; Tetrodotoxin; Yohimbine | 1991 |
Noradrenaline receptors participate in the regulation of GABAergic inhibition in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atenolol; Bicuculline; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Norepinephrine; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, GABA-A; Synapses | 1991 |
Differences between full and partial alpha-adrenoceptor agonists in eliciting phasic and tonic types of responses in the longitudinal smooth muscle of the rat portal vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenoxybenzamine; Portal Vein; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Vasoconstriction | 1991 |
Modulation of calcium currents via alpha 2-adrenoceptors in embryonic chick sympathetic neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Chick Embryo; Clonidine; Electric Stimulation; Electrophysiology; Ganglia, Sympathetic; Neurons; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1991 |
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine | 1991 |
Comparison of the effects of four dendrotoxin peptides, 4-aminopyridine and tetraethylammonium on the electrically evoked [3H]noradrenaline release from rat hippocampus.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Elapid Venoms; Electric Stimulation; Hippocampus; Male; Norepinephrine; Peptide Fragments; Peptides; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetraethylammonium; Tetraethylammonium Compounds; Tritium | 1991 |
Regionally specific age-dependent decline in alpha 2-adrenoceptors: an autoradiographic study in human brain.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Aging; Autoradiography; Brain; Brimonidine Tartrate; Clonidine; Humans; Middle Aged; Organ Specificity; Postmortem Changes; Quinoxalines; Receptors, Adrenergic, alpha; Tritium | 1991 |
Interaction between norepinephrine and serotonin in the neuroendocrine control of growth hormone release in the rat.
Topics: 5,7-Dihydroxytryptamine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Cyproheptadine; Fenclonine; Growth Hormone; Growth Hormone-Releasing Hormone; Hydroxyindoleacetic Acid; Hypothalamus; Male; Metergoline; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Serotonin Antagonists | 1990 |
Inhibition of cAMP production by alpha 2-adrenoceptor stimulation in rabbit retina.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; GTP-Binding Proteins; In Vitro Techniques; Pertussis Toxin; Phosphoric Diester Hydrolases; Quinoxalines; Rabbits; Retina; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Selective reduction of alpha 2-adrenergic responsiveness in hamster adipose tissue during prolonged starvation.
Topics: Adenosine Deaminase; Adipose Tissue; Adrenergic beta-Agonists; Alprostadil; Animals; Blood Proteins; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Fatty Acids, Nonesterified; Lipolysis; Male; Mesocricetus; Phenylisopropyladenosine; Quinoxalines; Receptors, Adrenergic, beta; Reference Values; Starvation | 1990 |
Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes.
Topics: Absorption; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Chromatography, High Pressure Liquid; Clonidine; Conjunctiva; Cornea; Eye; Female; Perfusion; Permeability; Quinoxalines; Rabbits; Sclera; Solubility; Tissue Distribution | 1990 |
Influence of androgenic status on the alpha 2/beta-adrenergic control of lipolysis in white fat cells: predominant alpha 2-antilipolytic response in testosterone-treated-castrated hamsters.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Male; Mesocricetus; Niacin; Orchiectomy; Phentolamine; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Testosterone | 1988 |
Alpha 2-adrenoceptor-mediated inhibition of histamine release from rat cerebral cortical slices.
Topics: Animals; Brimonidine Tartrate; Cerebral Cortex; Clonidine; Histamine Release; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Functional alpha 2-adrenoceptors in rat adipocytes: inhibition of cyclic AMP accumulation.
Topics: Adenylate Cyclase Toxin; Adipose Tissue; Animals; Brimonidine Tartrate; Clonidine; Colforsin; Cricetinae; Cyclic AMP; Male; Pertussis Toxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1989 |
The effects of acute and chronic desipramine on the thermogenic and hypoactivity responses to alpha 2-agonists in reserpinized and normal mice.
Topics: Adrenergic alpha-Agonists; Animals; Body Temperature Regulation; Brimonidine Tartrate; Clonidine; Desipramine; Female; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Quinoxalines; Reserpine | 1989 |
Interactions of full and partial agonists with HT29 cell alpha 2-adrenoceptor: comparative study of [3H]UK-14,304 and [3H]clonidine binding.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guanylyl Imidodiphosphate; Kinetics; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Tritium; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Yohimbine | 1989 |
Human fat cell alpha-2 adrenoceptors. II. Comparative study of partial and full agonist binding parameters using [3H]clonidine and [3H]UK-14,304.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Allosteric Regulation; Binding, Competitive; Brimonidine Tartrate; Clonidine; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Kinetics; Magnesium; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
The paradox of alpha 2 adrenergic regulation of prolactin (PRL) secretion. I. The PRL-releasing action of the alpha 2 receptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Growth Hormone; Injections, Intravenous; Male; Nervous System; Prolactin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1989 |
Imidazolinic radioligands for the identification of hamster adipocyte alpha 2-adrenoceptors.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cricetinae; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipolysis; Male; Mesocricetus; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Characterization of dog fat cell adrenoceptors: variations in alpha-2 and beta adrenergic receptors distribution according to the extent of the fat deposits and the anatomical location.
Topics: Adipose Tissue; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Cyclic AMP; Dihydroalprenolol; Dogs; Epinephrine; Humans; Isoproterenol; Lipolysis; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1987 |
Alpha 2-receptors mediate catecholamine-stimulated acid secretion in Amphiuma jejunum.
Topics: Animals; Brimonidine Tartrate; Clonidine; In Vitro Techniques; Jejunum; Methoxamine; Norepinephrine; Phenylephrine; Propranolol; Protons; Quinoxalines; Receptors, Adrenergic, alpha; Stimulation, Chemical; Urodela | 1988 |
Norepinephrine inhibits calcium action potential through alpha 2-adrenoceptors in rabbit vesical parasympathetic neurons.
Topics: Action Potentials; Animals; Brimonidine Tartrate; Calcium; Clonidine; Ganglia, Parasympathetic; Male; Norepinephrine; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1988 |
Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Brain; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Pulmonary Artery; Quinoxalines; Rabbits; Rats; Receptors, Adrenergic, alpha; Sulfonamides; Tritium; Vas Deferens | 1985 |
Interactions of dimethoxy-substituted tolazoline derivatives with alpha 1- and alpha 2-adrenoreceptors in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta; Brain; Brimonidine Tartrate; Clonidine; Dioxanes; Electric Stimulation; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tolazoline | 1985 |
A difference in the affinity of some selective alpha 2-adrenoceptor antagonists when compared on isolated vasa deferentia of rat and rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Quinoxalines; Rabbits; Rats; Vas Deferens | 1985 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Agonist and antagonist binding to alpha 2-adrenergic receptors in purified membranes from human platelets. Implications of receptor-inhibitory nucleotide-binding protein stoichiometry.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Clonidine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; NAD; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Alpha 2-adrenergic receptor turnover in adipose tissue and kidney: irreversible blockade of alpha 2-adrenergic receptors by benextramine.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Clonidine; Cricetinae; Cystamine; Dose-Response Relationship, Drug; Kidney; Lipid Mobilization; Male; Quinoxalines; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Evidence for a receptor mediated action of norepinephrine distinct from alpha- and beta-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cystamine; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Quinoxalines; Receptors, Adrenergic | 1986 |
Tight agonist binding may prevent the correct interpretation of agonist competition binding curves for alpha 2-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cell Membrane; Clonidine; Dioxanes; Epinephrine; Idazoxan; Kinetics; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha; Retina | 1987 |
Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brain; Brimonidine Tartrate; Clonidine; Female; Imidazoles; In Vitro Techniques; Male; Medetomidine; Muscle, Smooth; Mydriatics; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Vas Deferens | 1988 |
Mechanism of synaptic inhibition by noradrenaline acting at alpha 2-adrenoceptors.
Topics: Algorithms; Animals; Brimonidine Tartrate; Clonidine; Electric Conductivity; Guinea Pigs; Membrane Potentials; Norepinephrine; Potassium; Quinoxalines; Receptors, Adrenergic, alpha; Synapses | 1988 |
Evidence of functional alpha 2-adrenergic receptors in adult-rat adipocytes by using the agonist UK 14304.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Age Factors; Animals; Brimonidine Tartrate; Cell Membrane; Clonidine; Epinephrine; In Vitro Techniques; Lipolysis; Male; Quinoxalines; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Adrenergic, alpha; Theophylline | 1988 |
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Tolazoline; Yohimbine | 1985 |
Platelet high affinity adrenoceptor binding sites labelled with the agonist [3H]UK-14,304, in depressed patients and matched controls.
Topics: Adult; Blood Platelets; Brimonidine Tartrate; Clonidine; Depression; Female; Humans; Kinetics; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha | 1986 |
Alpha-2-adrenergic control of prolactin release.
Topics: Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Male; Piperoxan; Pregnancy; Prolactin; Quinolizines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line. Alpha 2-adrenergic agonists counteract effect of vasoactive intestinal peptide.
Topics: Adenocarcinoma; Brimonidine Tartrate; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Epinephrine; Fructosediphosphates; Hexosediphosphates; Humans; Quinoxalines; Vasoactive Intestinal Peptide; Yohimbine | 1986 |
[3H] UK-14,304, a new agonist ligand of alpha 2-adrenoceptors: a comparative study with human and rat tissue.
Topics: Adult; Animals; Binding, Competitive; Blood Platelets; Brimonidine Tartrate; Cerebral Cortex; Clonidine; Humans; Kinetics; Ligands; Middle Aged; Psychotropic Drugs; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1987 |
Beta-endorphin: a common factor in the antihypertensive action of clonidine-type imidazolines in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; beta-Endorphin; Blood Pressure; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Endorphins; Hypertension; Imidazoles; Injections, Intraventricular; Male; Quinoxalines; Rats | 1985 |
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Clonidine; Dogs; Female; Heart; Heart Rate; Imidazoles; Male; Norepinephrine; Oxymetazoline; Pentobarbital; Quinoxalines; Rats; Spinal Cord; Synapses; Tachycardia; Vagotomy | 1982 |
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Chickens; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; Phenylacetates; Quinoxalines; Receptors, Adrenergic, alpha; Sleep; Thiophenes; Time Factors; Xylazine | 1983 |
Effect of 781094, a new selective alpha-adrenoceptor antagonist, on the aggregatory responses of human blood platelets and on binding of [3H]-dihydroergocryptine to these cells.
Topics: Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Clonidine; Dihydroergotoxine; Dioxins; Epinephrine; Humans; Idazoxan; Methoxamine; Platelet Aggregation; Quinoxalines; Serotonin; Tritium | 1983 |
Alpha 2-adrenoceptor agonists potentiate responses mediated by alpha 1-adrenoceptors in the cat nictitating membrane.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nictitating Membrane; Norepinephrine; Phenylephrine; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha | 1984 |
Pharmacological characterization of alpha adrenoceptors in the rat gastric fundus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Methacholine Compounds; Muscle Contraction; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha | 1984 |
Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Calcimycin; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Indoles; Isoindoles; Male; Norepinephrine; Pain Measurement; Peripheral Nervous System; Quinoxalines; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Effects of three alpha 2-adrenoceptor agonists, rilmenidine, UK 14304 and clonidine on bradykinin- and substance P-induced airway microvascular leakage in guinea-pigs.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Capillaries; Capillary Permeability; Clonidine; Dioxanes; Extravascular Lung Water; Guinea Pigs; Idazoxan; Oxazoles; Prazosin; Quinoxalines; Rilmenidine; Substance P; Trachea | 1995 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Contrasting effects of the imidazol(in)e alpha 2-adrenoceptor agonists, medetomidine, clonidine and UK 14,304 on extraneuronal levels of noradrenaline in the rat frontal cortex: evaluation using in vivo microdialysis and synaptosomal uptake studies.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Frontal Lobe; Imidazoles; Male; Medetomidine; Microdialysis; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptosomes; Time Factors | 1995 |
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by mu opioid and alpha-2 adrenergic agonists in guinea pig ileum.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Choline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Neurotransmitter Uptake Inhibitors; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Opioid, mu; Substance P; Synaptic Transmission | 1993 |
Apraclonidine and brimonidine effects on anterior ocular and cardiovascular physiology in normal and sympathectomized monkeys.
Topics: Adrenergic alpha-Agonists; Animals; Aqueous Humor; Blood Pressure; Body Weight; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Intraocular Pressure; Macaca fascicularis; Macaca mulatta; Male; Pupil; Quinoxalines; Refraction, Ocular; Sympathectomy | 1994 |
Adrenergic modulation of a spinal sympathetic reflex in the rat.
Topics: Animals; Brimonidine Tartrate; Clonidine; Male; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Spinal Cord; Sympathetic Nervous System | 1995 |
Agmatine recognizes alpha 2-adrenoceptor binding sites but neither activates nor inhibits alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Agmatine; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Clonidine; Cyclic AMP; In Vitro Techniques; Male; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1995 |
Effects of alpha-adrenoceptor agonists and antagonists on metabolic rate in cattle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Basal Metabolism; Body Temperature; Brimonidine Tartrate; Cattle; Clonidine; Dioxanes; Female; Guanfacine; Heart Rate; Idazoxan; Male; Prazosin; Quinoxalines | 1995 |
The NMDA receptor complex modulates clonidine-induced increases in growth hormone levels in rats.
Topics: Animals; Clonidine; Growth Hormone; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
Modulation of electrically evoked [3H]-noradrenaline release from cultured chick sympathetic neurons.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Clonidine; Electric Stimulation; Isoproterenol; Neurons; Norepinephrine; Quinoxalines; Receptors, Adrenergic; Receptors, Glutamate; Sensitivity and Specificity; Sympathetic Nervous System; Temperature; Tetrodotoxin; Tritium | 1994 |
Acute and chronic effects of reserpine on biochemical and functional parameters of central and peripheral alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Clonidine; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Injections, Subcutaneous; Male; Mydriasis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Reserpine; Tyrosine 3-Monooxygenase; Vas Deferens | 1993 |
Chloroethylclonidine irreversibly activates postjunctional alpha 2-adrenoceptors in the dog saphenous vein.
Topics: Adrenergic alpha-Agonists; Alkylating Agents; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Saphenous Vein | 1993 |
Nitric oxide modulates sympathetic vasoconstriction and basal blood flow in normal and acutely inflamed rabbit knee joints.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arthritis; Blood Pressure; Brimonidine Tartrate; Clonidine; Electric Stimulation; Infusions, Intra-Arterial; Knee Joint; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Quinoxalines; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1993 |
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine | 1993 |
Noradrenaline decreases transmission of NMDA- and non-NMDA-receptor mediated monosynaptic EPSPs in rat prefrontal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Antagonists; Afferent Pathways; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Methoxamine; Neurons; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Prefrontal Cortex; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
Density of alpha-2A adrenoceptors and Gi proteins in the human brain: ratio of high-affinity agonist sites to antagonist sites and effect of age.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Brain Chemistry; Brimonidine Tartrate; Child; Child, Preschool; Clonidine; Dioxanes; Female; GTP-Binding Proteins; Humans; Idazoxan; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2 | 1994 |
Alpha 2-adrenergic stimulation promotes preadipocyte proliferation. Involvement of mitogen-activated protein kinases.
Topics: 3T3 Cells; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Clone Cells; Clonidine; Cyclic AMP; Dioxanes; Humans; Idazoxan; Kinetics; Male; Mice; Pertussis Toxin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1994 |
ATP-sensitive K+ channels mediate alpha 2D-adrenergic receptor contraction of arteriolar smooth muscle and reversal of contraction by hypoxia.
Topics: Adenosine Triphosphate; Animals; Brimonidine Tartrate; Cell Hypoxia; Clonidine; Glyburide; In Vitro Techniques; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1995 |
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Epinephrine; Heart Rate; Hyperglycemia; Idazoxan; Indoles; Male; Mice; Motor Activity; Norepinephrine; Peripheral Nerves; Prazosin; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction | 1993 |
Inhibition by alpha 2-adrenoceptor agonists of contractions of rabbit isolated colon elicited by pelvic nerve stimulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Colon; Drug Resistance; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pelvis; Quinoxalines; Rabbits | 1993 |
Acute and chronic effects of cholinesterase inhibitors and pilocarpine on the density and sensitivity of central and peripheral alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Cholinesterase Inhibitors; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Isoflurophate; Male; Neostigmine; Physostigmine; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tyrosine 3-Monooxygenase; Vas Deferens | 1993 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Male; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Diabetes Mellitus, Experimental; Hypertension; Imidazoles; Nifedipine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
Clonidine-induced increase in osmolar clearance and free water clearance via activation of two distinct alpha 2-adrenoceptor sites.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Male; Naltrexone; Osmolar Concentration; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Water | 1996 |
A simple method for measuring the effects of drugs on intestinal longitudinal and circular muscle.
Topics: Animals; Atropine; Brimonidine Tartrate; Clonidine; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1996 |
Acetylcholine release in the rat prefrontal cortex in vivo: modulation by alpha 2-adrenoceptor agonists and antagonists.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Guanabenz; Idazoxan; Imidazoles; Male; Microdialysis; Piperoxan; Prefrontal Cortex; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley | 1997 |
Efficacy and kinetics of opioid action on acutely dissociated neurons.
Topics: Animals; Brimonidine Tartrate; Calcium Channels; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Locus Coeruleus; Morphine; Narcotics; Potassium Channels; Quinoxalines | 1997 |
Mechanisms of adrenergic agonist induced allergy bioactivation and antigen formation.
Topics: Adrenergic alpha-Agonists; Allergens; Amodiaquine; Brimonidine Tartrate; Clonidine; Epinephrine; Glutathione; Horseradish Peroxidase; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Quinoxalines | 1997 |
Characterisation of pre- and post-synaptic alpha-adrenoceptors in modulation of the rat ileum longitudinal and circular muscle activities.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Clonidine; Electric Stimulation; Idazoxan; Ileum; In Vitro Techniques; Muscle Contraction; Oxymetazoline; Phentolamine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Presynaptic | 1997 |
The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Models, Theoretical; Norepinephrine; Quinolines; Quinoxalines; Rats | 1997 |
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1997 |
Noradrenergic influences on prefrontal cortical cognitive function: opposing actions at postjunctional alpha 1 versus alpha 2-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Azepines; Brimonidine Tartrate; Clonidine; Cognition; Discrimination, Psychological; Guanfacine; Haplorhini; Memory; Norepinephrine; Quinoxalines; Reaction Time; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Visual Perception | 1998 |
Selective increase of alpha2A-adrenoceptor agonist binding sites in brains of depressed suicide victims.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Autoradiography; Binding, Competitive; Brain Chemistry; Brimonidine Tartrate; Cell Membrane; Clonidine; Depression; Female; Frontal Lobe; Humans; Idazoxan; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2; Suicide; Tritium | 1998 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Prejunctional alpha2-adrenoceptors and peroxide-induced potentiation of norepinephrine release from the bovine iris.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Brimonidine Tartrate; Cattle; Clonidine; Culture Techniques; Hydrogen Peroxide; Iris; Neuroeffector Junction; Norepinephrine; Oxymetazoline; Perfusion; Quinoxalines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Tritium; Yohimbine | 1998 |
Update in glaucoma: the new pharmacotherapies. Brimonidine versus apraclonidine.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Clonidine; Glaucoma; Humans; Quinoxalines | 1998 |
[New drugs in glaucoma therapy].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Rilmenidine reveals differences in the pharmacological characteristics of prejunctional alpha2-adrenoceptors in the guinea-pig, rat and pig.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Arteries; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Oxazoles; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Rilmenidine; Species Specificity; Swine; Vas Deferens | 1998 |
Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Biological Transport; Brimonidine Tartrate; Clonidine; Cyclopropanes; Desipramine; Drug Administration Schedule; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Injections, Subcutaneous; Kinetics; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Mesencephalon; Milnacipran; Neurons; Norepinephrine; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Spiperone; Time Factors | 1998 |
Pharmacological evidence for different alpha 2-adrenergic receptor sites mediating analgesia and sedation in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics, Non-Narcotic; Animals; Brimonidine Tartrate; Clonidine; Conscious Sedation; Hypnotics and Sedatives; Imidazoles; Injections, Intraventricular; Injections, Spinal; Male; Medetomidine; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 1998 |
Role of alpha2-adrenoceptors on the hyperglycaemic and insulin secretory effects derived from alpha1- and beta-adrenoceptor stimulation in the rabbit.
Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Ethanolamines; Heart Rate; Hyperglycemia; Insulin; Insulin Secretion; Lactic Acid; Male; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta | 1998 |
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonidine Tartrate; Cell Count; Cell Survival; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Retinal Ganglion Cells; Timolol; Yohimbine | 1999 |
Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Benzofurans; Brimonidine Tartrate; Clonidine; Dopamine Agonists; Idazoxan; Imidazoles; Ligands; Male; Methylphenidate; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Stereoisomerism; Stereotyped Behavior; Substantia Nigra | 1999 |
Modulation of relative intrinsic activity of agonists at the alpha-2A adrenoceptor by mutation of residue 351 of G protein gi1alpha.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; COS Cells; Cysteine; Dose-Response Relationship, Drug; Epinephrine; Glycine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Point Mutation; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Swine; Yohimbine | 1999 |
Ultrabiomicroscopic study of the effects of brimonidine, apraclonidine, latanoprost and ibopamine on the chamber angle and ciliary body.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Chamber; Brimonidine Tartrate; Ciliary Body; Clonidine; Deoxyepinephrine; Female; Follow-Up Studies; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Mydriatics; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Reference Values; Ultrasonography | 1998 |
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Approval; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Netherlands; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1999 |
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine | 1998 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Determination of the somatodendritic alpha2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Brimonidine Tartrate; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Dendritic Cells; Drug Interactions; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Time Factors | 1999 |
Effects of some imidazolidine alpha2-adrenoceptor agonists in rat isolated atria.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Electric Stimulation; Female; Heart Atria; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Muscle Contraction; Norepinephrine; Pargyline; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 1999 |
Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometry.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Binding, Competitive; Biosensing Techniques; Brimonidine Tartrate; CHO Cells; Cholera Toxin; Clonidine; Cricetinae; Dexmedetomidine; Egtazic Acid; Humans; Hydrogen-Ion Concentration; Norepinephrine; Pertussis Toxin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Virulence Factors, Bordetella | 1999 |
The mechanisms of alpha(2)-adrenoceptor agonist-induced contraction in longitudinal muscle of the porcine uterus.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Colforsin; Cyclic AMP; Female; Fluorescent Dyes; Fura-2; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myometrium; Pertussis Toxin; Quinoxalines; Swine; Uterus; Verapamil; Virulence Factors, Bordetella | 2000 |
Oxytocin/alpha(2)-Adrenoceptor interactions in feeding responses.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain; Brimonidine Tartrate; Clonidine; Eating; Injections, Intraventricular; Male; Oxytocin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tissue Distribution | 2000 |
Incidence of brimonidine allergy in patients previously allergic to apraclonidine.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Clonidine; Conjunctivitis; Cross Reactions; Dermatitis, Allergic Contact; Drug Hypersensitivity; Female; Glaucoma; Humans; Hyperemia; Incidence; Male; Middle Aged; Quinoxalines; Retrospective Studies; Risk Factors | 2000 |
Alpha-2 adrenoceptors are present in rat aorta smooth muscle cells, and their action is mediated by ATP-sensitive K(+) channels.
Topics: Adenosine Triphosphate; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 2000 |
Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist:antagonist interactions.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Azepines; Brimonidine Tartrate; Calcium; CHO Cells; Clonidine; Cricetinae; DNA, Recombinant; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Idazoxan; Kinetics; Medetomidine; Mice; Oxymetazoline; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Transfection | 2000 |
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Gene Expression Regulation; GTP-Binding Proteins; Idazoxan; Male; Membranes; Norepinephrine; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; RNA, Messenger; Tritium | 2001 |
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 2001 |
Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cheek; Clonidine; Cricetinae; Humans; Mesocricetus; Muscle, Smooth, Vascular; Quinoxalines; Retina; Retinal Vessels; Vasoconstriction | 2001 |
Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Ciliary Arteries; Clonidine; Dose-Response Relationship, Drug; Isometric Contraction; Muscle, Smooth, Vascular; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine; Vasoconstriction | 2001 |
Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds; Brimonidine Tartrate; Calbindin 2; Cell Death; Choline O-Acetyltransferase; Clonidine; Electroretinography; Heptanes; Imidazoline Receptors; Immunohistochemistry; Membrane Potentials; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reperfusion Injury; Retina; Retinal Ganglion Cells; S100 Calcium Binding Protein G; Yohimbine | 2001 |
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine | 2001 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine | 2001 |
Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity.
Topics: Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Carbazoles; Cerebral Cortex; Clonidine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Models, Neurological; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phenazocine; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Scopolamine | 2002 |
Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Binding, Competitive; Brimonidine Tartrate; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Idazoxan; Middle Cerebral Artery; Norepinephrine; Phenylephrine; Pregnancy; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2002 |
Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Female; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Naloxone; Quinoxalines; Receptors, Opioid, mu; Somatostatin | 2002 |
Changes of the excitability of rat trigeminal root ganglion neurons evoked by alpha(2)-adrenoreceptors.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Brimonidine Tartrate; Cell Membrane; Cells, Cultured; Clonidine; Gene Expression Regulation; Ion Channels; Neural Inhibition; Neurons, Afferent; Protein Isoforms; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; RNA, Messenger; Trigeminal Ganglion; Trigeminal Neuralgia | 2002 |
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Azepines; Brimonidine Tartrate; Clonidine; Idazoxan; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxazoles; Prostaglandins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Yohimbine | 2002 |
Role of alpha2-adrenergic receptors and cyclic adenosine monophosphate-dependent protein kinase in the regulation of norepinephrine release in the central nervous system of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Central Nervous System; Clonidine; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Isoquinolines; Male; Medulla Oblongata; Norepinephrine; Pertussis Toxin; Presynaptic Terminals; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 2003 |
No evidence for activation of alpha(2)-adrenoceptors by methanolic extracts of bovine brain and lung containing clonidine-displacing substance.
Topics: Adrenergic alpha-Agonists; Animals; Brain Chemistry; Brimonidine Tartrate; Cattle; Clonidine; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Lung; Male; Methanol; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Swine; Tissue Extracts; Vas Deferens; Veins | 2003 |
alpha2-Adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Clonidine; GTP-Binding Proteins; Neocortex; Norepinephrine; Patch-Clamp Techniques; Pertussis Toxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2004 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Dexmedetomidine; Endocytosis; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Northern; Brimonidine Tartrate; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; Gene Expression Regulation; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine | 2005 |
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: functional evaluation in rat and rabbit tissues.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methoxamine; Molecular Structure; Muscle Contraction; Norepinephrine; Quinazolines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstriction | 2005 |
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Bridged Bicyclo Compounds; Brimonidine Tartrate; Clonidine; Coronary Circulation; Drug Synergism; Female; Heart; Heart Rate; Heptanes; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Myocardium; Perfusion; Phenoxybenzamine; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Brimonidine Tartrate; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methoxamine; Nitric Oxide; Phenylephrine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin; Vasoconstrictor Agents; Vasodilation; Yohimbine | 2006 |
Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Radiation; Electric Stimulation; Functional Laterality; Hippocampus; Hyperalgesia; In Situ Hybridization; In Vitro Techniques; Locus Coeruleus; Male; Norepinephrine; Pain Measurement; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sciatica; Tumor Necrosis Factor-alpha | 2007 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Alpha 2A-adrenoceptor-specific stimulation of [35S]GTP gamma S binding to membrane preparations of rat frontal cortex.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Emotions; Guanfacine; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoquinolines; Kinetics; Membranes; Naphthyridines; Prefrontal Cortex; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Signal Transduction; Stress, Psychological | 2008 |
Inhibition of opioid release in the rat spinal cord by alpha2C adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Brimonidine Tartrate; Clonidine; Data Interpretation, Statistical; Electric Stimulation; Enkephalins; Guanfacine; Immunohistochemistry; Male; Medetomidine; Microscopy, Confocal; Oligopeptides; Protease Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Veratridine | 2008 |
Partial agonism at the human alpha(2A)-autoreceptor: role of binding duration.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Autoreceptors; Brimonidine Tartrate; Child; Child, Preschool; Clonidine; Female; Guanfacine; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Neocortex; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Temperature; Time Factors; Young Adult | 2008 |
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2009 |
[Current and future medical drugs for smoking cessation].
Topics: Adrenergic alpha-Agonists; Antidepressive Agents; Behavior Therapy; Benzazepines; Bupropion; Cannabinoid Receptor Antagonists; Clinical Trials as Topic; Clonidine; Combined Modality Therapy; Counseling; Humans; Nicotine; Nicotinic Agonists; Nortriptyline; Piperidines; Pyrazoles; Quinoxalines; Rimonabant; Smoking Cessation; Tobacco Use Disorder; Vaccines; Varenicline | 2009 |
Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Binding, Competitive; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Humans; Linear Models; Norepinephrine; Polymorphism, Genetic; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Signal Transduction; Transfection | 2010 |
Current treatment options in smoking cessation.
Topics: Adrenergic alpha-Agonists; Antidepressive Agents; Behavior Therapy; Benzazepines; Bupropion; Clonidine; Combined Modality Therapy; Counseling; Humans; Nicotine; Nicotinic Agonists; Nortriptyline; Patient Selection; Piperidines; Practice Guidelines as Topic; Pyrazoles; Quinoxalines; Rimonabant; Self-Help Groups; Smoking Cessation; Tobacco Use Disorder; United States; Vaccines; Varenicline | 2010 |
Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Autoradiography; Axons; Brimonidine Tartrate; Clonidine; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique, Indirect; Glaucoma; Glial Fibrillary Acidic Protein; Optic Nerve Injuries; Organ Culture Techniques; Platelet Activating Factor; Protein Disulfide-Isomerases; Proteomics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Laminin; Retina; Retinal Degeneration; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Smoking cessation pharmacotherapy: a concise overview.
Topics: Adrenergic alpha-2 Receptor Agonists; Antidepressive Agents; Benzazepines; Bupropion; Clonidine; Humans; Nicotine; Nicotinic Agonists; Nortriptyline; Quinoxalines; Smoking; Smoking Cessation; Varenicline | 2011 |
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Guanfacine; Imidazoles; Imidazoline Receptors; Isoquinolines; Male; Motor Activity; Naphthyridines; Prazosin; Propranolol; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2011 |
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Clonidine; Desipramine; Disease Models, Animal; Idazoxan; Locus Coeruleus; Male; MAP Kinase Signaling System; Medulla Oblongata; Neuralgia; Norepinephrine; Prefrontal Cortex; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Cord | 2012 |
Presynaptic inhibition of glutamate transmission by α2 receptors in the VTA.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brimonidine Tartrate; Clonidine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Mice; Neural Inhibition; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Tetrodotoxin; Ventral Tegmental Area | 2012 |
The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Idazoxan; Male; Methoxamine; Movement; Neurons; Norepinephrine; Nucleus Accumbens; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2012 |
Protein kinase Cε is required for spinal analgesic synergy between delta opioid and alpha-2A adrenergic receptor agonist pairs.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Anesthesia, Spinal; Animals; Brimonidine Tartrate; Clonidine; Drug Synergism; Enzyme Inhibitors; Female; Immunohistochemistry; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Protein Kinase C-epsilon; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Opioid, delta; Spinal Cord | 2013 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |