quinoxalines has been researched along with 8-bromocyclic gmp in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (21.05) | 18.2507 |
| 2000's | 63 (66.32) | 29.6817 |
| 2010's | 12 (12.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okada, D; Shibuki, K | 1 |
| Loweth, AC; Morgan, NG; Scarpello, JH; Williams, GT | 1 |
| Bloch, DB; Bloch, KD; Filippov, G | 1 |
| Alam, J; Choi, AM; Cook, JL; Hartsfield, CL | 1 |
| Franck, H; Sanders, KM; Shuttleworth, CW; Sweeney, KM | 1 |
| Campbell, WB; Jin, MW; Li, PL | 1 |
| Cantabrana, B; Hidalgo, A; Menéndez Antolin, L; Pérez Vallina, JR; Sánchez, M | 1 |
| Iadecola, C; Yang, G | 1 |
| Canning, BJ; Fischer, A | 1 |
| Nawy, S; Stanton, PK; Wexler, EM | 1 |
| Muneoka, Y; Pedder, SM; Walker, RJ | 1 |
| Fernández-Tomé, P; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 2 |
| Deichmann, PC; Falck, JR; Imig, JD; Inscho, EW; Reddy, KM | 1 |
| Carvalho, AP; Carvalho, CM; Sequeira, SM | 1 |
| Diamond, J; Sandirasegarane, L | 1 |
| Catalin, D; Miolan, JP; Niel, JP; Quinson, N | 1 |
| Duszyk, M; Thethi, K | 1 |
| Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C | 1 |
| Vaziri, ND; Wang, XQ | 1 |
| Berkels, R; Klaus, W; Roesen, R; Suerhoff, S | 1 |
| Barsacchi, R; Cantoni, O; Clementi, E; De Nadai, C; Lièvremont, JP; Meldolesi, J; Moncada, S; Sciorati, C; Sestili, P | 1 |
| Kato, T; Nakamura, K; Yamamoto, H; Yamamoto, T; Yuyama, K | 1 |
| Barrachina, MD; Esplugues, JV; García-Zaragozá, E; Moreno, L | 1 |
| Johns, RA; Li, D; Shirakami, G; Zhan, X | 1 |
| Baumgarten, G; Dibbs, Z; Kalra, D; Mann, DL; Seta, Y; Sivasubramanian, N | 1 |
| Bicker, G; Seidel, C | 1 |
| Homer, KL; Wanstall, JC | 1 |
| Budelmann, BU; Tu, Y | 1 |
| Karlsson, AM; Loitto, VM; Nilsson, HM; Sundqvist, T; Svensson, SP | 1 |
| Ellis, DZ; Nathanson, JA; Sweadner, KJ | 1 |
| Al-Hassani, M; Gupta, MP; Hart, CM; Natarajan, V; Ober, MD; Patterson, C | 1 |
| Gustafsson, LE; Hallén, K; Olgart, C; Wiklund, NP | 1 |
| Cernuda-Morollón, E; Díaz-Cazorla, M; Lamas, S; Pérez-Sala, D; Rodríguez-Pascual, F | 1 |
| Diamond, J; Hennan, JK | 1 |
| Aonuma, H; Newland, PL | 1 |
| Prado, WA; Sousa, AM | 1 |
| Ingram, JN; Renfree, MB; Shaw, G | 1 |
| Aldieri, E; Bosia, A; Costamagna, C; Ghigo, D; Lindblom, B; Massobrio, M; Moffa, F; Ochetti, S; Revelli, A | 1 |
| Brodowsky, R; Dirnagl, U; Dreier, JP; Klee, R; Lindauer, U; Lobsien, E; Schuh-Hofer, S; Vogt, J | 1 |
| Basini, G; Bussolati, S; Grasselli, F; Ponderato, N; Tamanini, C | 1 |
| Carey, RM; Jin, XH; Siragy, HM | 1 |
| Gutiérrez, AM; Liu, R; Persson, AEG; Ring, A | 1 |
| Bolton, TB; Gordienko, DV; Pucovský, V | 1 |
| Abreu, P; Gonzalez, MC; Sanchez, JJ | 1 |
| Graier, WF; Groschner, K; Malli, R; Schmidt, K; Thyagarajan, B | 1 |
| Fujimoto, S; Mori, M; Tsushima, H | 1 |
| Ishikawa, T; Kaneko, Y; Nakayama, K; Sugino, F | 1 |
| Befus, AD; Cass, C; Graham, K; Marcet-Palacios, M; Mayers, I; Radomski, MW | 1 |
| Morato, GS; Wazlawik, E | 1 |
| Chan, SL; Fiscus, RR | 1 |
| Brørs, O; Jensen, J; Melien, Ø; Sharikabad, MN; Østbye, KM | 1 |
| Carey, RM; Felder, RA; Gildea, JJ; Jin, XH; McGrath, HE; Siragy, HM | 1 |
| Brading, AF; Deka, DK | 1 |
| Barkoudah, E; Jaggar, JH; Leffler, CW | 1 |
| Dorovini-Zis, K; Vincent, SR; Wong, D | 1 |
| Ahn, DS; Chung, SS; Lee, HG; Lee, YH; Nam, TS | 1 |
| Dorovini-Zis, K; Prameya, R; Vincent, SR; Wong, D; Wu, V | 1 |
| Elmedal Laursen, B; Mulvany, MJ; Simonsen, U | 1 |
| Bianciotti, LG; di Nunzio, A; Hope, SI; Legaz, G; Morgazo, C; Perfume, G; Vatta, MS | 1 |
| Bose, D; Bose, R; Cheng, ZQ; Duke, K; Jacobs, H; Light, RB; Mink, SN; Roberts, DE | 1 |
| Kamei, J; Saitoh, A; Tamura, N | 1 |
| Cao, S; Chatterjee, S; Farrugia, G; Gadgil, J; Gibbons, SJ; Langer, DA; Perri, RE; Shah, VH | 1 |
| Chan, SL; Chan, SS; Fiscus, RR; Fraser, M; Tsang, BK | 1 |
| Hull, EM; Sato, SM | 1 |
| Bennett, VJ; Papaconstandinou, NA; Reynolds, IJ; Rintoul, GL | 1 |
| Chmelíková, E; Jílek, F; Lánská, V; Petr, J; Pribánová, M; Rajmon, R; Tománek, M | 1 |
| Furukawa, K; Motomura, S; Seya, K | 1 |
| Abu-Soud, HM; Diamond, MP; Gonik, B; Goud, AP; Goud, PT | 1 |
| Antonov, AS; Antonova, GN; Catravas, JD; Dimitropoulou, C; Snead, CM; Venema, RC | 1 |
| Kim, M; Perrino, BA | 1 |
| Arnolda, LF; Holobotovskyy, VV; Malik, V; McKitrick, DJ; Phillips, JK | 1 |
| Befus, AD; Duszyk, M; Duta, F; Duta, V; Puttagunta, L | 1 |
| Jang, Y; Mueller, RA; Norfleet, EA; Wang, H; Xi, J; Xu, Z | 1 |
| Bouallegue, A; Daou, GB; Srivastava, AK | 1 |
| Edwards, TM; Lindley, N | 1 |
| Anrather, J; Iadecola, C; Kawano, T; Kunz, A; Orio, M; Zhou, P | 1 |
| Dismuke, WM; Ellis, DZ; Mbadugha, CC | 1 |
| Brouckaert, P; Buys, E; Dhaese, I; Lefebvre, RA; Sips, P; Vanneste, G | 1 |
| Katiyar, SK; Punathil, T | 1 |
| Ishikawa, T; Nakayama, K; Noguchi, A; Takada, M | 1 |
| Dismuke, WM; Ellis, DZ; Sharif, NA | 1 |
| Kerschbaum, HH; Nimmervoll, B; Sacha, B; Svoboda, N | 1 |
| Arendshorst, WJ; Fellner, SK | 1 |
| Fiscus, RR; Johlfs, MG | 1 |
| Batalhao, ME; Branco, LG; Carnio, EC; Ravanelli, MI; Soriano, RN | 1 |
| Dou, D; Gao, Y; He, Q; Ma, H; Raj, JU; Wu, Y; Ying, L; Zheng, X | 1 |
| Claes, JM; Holmgren, S; Krönström, J; Mallefet, J | 1 |
| Komori, S; Matsuyama, H; Takewaki, T; Unno, T | 1 |
| Balfagón, G; Blanco-Rivero, J; Cogolludo, A; del Campo, L; Márquez-Rodas, I; Nava, MP; Pérez-Vizcaíno, F; Sastre, E | 1 |
| Gajdus, M; Glaza, I; Gurtowska, N; Rzepka, A; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R | 1 |
| Blouquit-Laye, S; Braun, C; Chinet, T; Dannhoffer, L; Dinh-Xuan, AT; Sage, E | 1 |
| Dismuke, WM; Liang, J; Overby, DR; Stamer, WD | 1 |
| Bae, H; Bang, H; Kim, JH; Kim, K; Kim, T; Ko, JH; Lee, HJ; Lim, I | 1 |
| Kosakai, K; Tsujiuchi, Y; Yoshino, M | 1 |
95 other study(ies) available for quinoxalines and 8-bromocyclic gmp
| Article | Year |
|---|---|
Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Cyclic GMP; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hemoglobins; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Potassium; Purkinje Cells; Pyridines; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15.
Topics: Alkaloids; Animals; Apoptosis; Carbazoles; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Indoles; Islets of Langerhans; Nitroso Compounds; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione | 1997 |
Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells.
Topics: Animals; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glutathione; Guanylate Cyclase; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Nitroso Compounds; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitrosoglutathione; Time Factors | 1997 |
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide.
Topics: Animals; Aorta; Carbon Monoxide; Cell Nucleus; Cells, Cultured; Cyclic GMP; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Nitrogen Oxides; Oligonucleotide Probes; Oxadiazoles; Quinoxalines; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Spermine; Transcription, Genetic | 1997 |
Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon.
Topics: Animals; Colon; Cyclic GMP; Dogs; Electric Stimulation; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines | 1997 |
Effect of selective inhibition of soluble guanylyl cyclase on the K(Ca) channel activity in coronary artery smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Iloprost; In Vitro Techniques; Kinetics; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nitroso Compounds; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channels; Quinoxalines; Scorpion Venoms; Vasodilation | 1998 |
Nitric oxide and cyclic nucleotides participate in the relaxation of diclofenac on rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Inhibitors; Female; GTP-Binding Proteins; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nucleotides, Cyclic; omega-N-Methylarginine; Oxadiazoles; Pertussis Toxin; Quinoxalines; Rats; Rats, Wistar; Sensitivity and Specificity; Sulfonamides; Uterine Contraction; Uterus; Vanadates; Vasodilator Agents; Virulence Factors, Bordetella | 1998 |
Activation of cerebellar climbing fibers increases cerebellar blood flow: role of glutamate receptors, nitric oxide, and cGMP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Harmaline; Male; Nerve Fibers; Nitric Oxide; Nitroarginine; Oxygen; Partial Pressure; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Tetrodotoxin; Ultrasonography, Doppler, Transcranial | 1998 |
Localization of heme oxygenase-2 immunoreactivity to parasympathetic ganglia of human and guinea-pig airways.
Topics: Animals; Atropine; Carbon Monoxide; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Parasympathetic; Ganglionic Blockers; Guanylate Cyclase; Guinea Pigs; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Muscarinic Antagonists; Muscle Contraction; Oxadiazoles; Protoporphyrins; Quinoxalines; Receptors, Cholinergic; Respiratory Physiological Phenomena; Respiratory System; Synaptic Transmission; Trimethaphan; Vagus Nerve | 1998 |
Nitric oxide depresses GABAA receptor function via coactivation of cGMP-dependent kinase and phosphodiesterase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Cyclic IMP; Enzyme Activation; Enzyme Inhibitors; Nitric Oxide; Nitroprusside; Oligopeptides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Retina; Sulfhydryl Reagents | 1998 |
Evidence for the involvement of nitric oxide in the inhibitory effect of GSPYFVamide on Helix aspersa central neurones.
Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glutathione; Guanylate Cyclase; Helix, Snails; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nitroso Compounds; Oligopeptides; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitrosoglutathione; Sodium Nitrite | 1998 |
Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.
Topics: Animals; Cell Death; Cyclic GMP; Drug Synergism; Enzyme Inhibitors; Hydrogen Peroxide; Molsidomine; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilator Agents | 1998 |
Afferent arteriolar vasodilation to the sulfonimide analog of 11, 12-epoxyeicosatrienoic acid involves protein kinase A.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; 8,11,14-Eicosatrienoic Acid; Animals; Arterioles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guanylate Cyclase; Histones; In Vitro Techniques; Isoquinolines; Juxtaglomerular Apparatus; Kidney Medulla; Kinetics; Male; Microscopy, Video; Muscle, Smooth, Vascular; Nephrons; Norepinephrine; Oxadiazoles; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides; Vasodilation | 1999 |
Both protein kinase G dependent and independent mechanisms are involved in the modulation of glutamate release by nitric oxide in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Nitric Oxide; Nitroprusside; Oxadiazoles; Presynaptic Terminals; Protein Kinases; Quinoxalines; Rats; Sulfhydryl Reagents; Synaptosomes; Thionucleotides | 1999 |
The nitric oxide donors, SNAP and DEA/NO, exert a negative inotropic effect in rat cardiomyocytes which is independent of cyclic GMP elevation.
Topics: Animals; Cardiotonic Agents; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Penicillamine; Quinoxalines; Rats; Rats, Wistar | 1999 |
Release of nitric oxide within the coeliac plexus is involved in the organization of a gastroduodenal inhibitory reflex in the rabbit.
Topics: Action Potentials; Animals; Arginine; Benzoates; Celiac Plexus; Cyclic GMP; Duodenum; Enzyme Inhibitors; Female; Gastrointestinal Motility; Imidazoles; Male; Muscle, Smooth; Nitric Oxide; Nitroarginine; Oxadiazoles; Quinoxalines; Rabbits; Reflex; Stomach | 1999 |
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1999 |
Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Quinoxalines; Rats; Thionucleotides | 1999 |
Different signalling pathways mediate the opposite effects of endogenous versus exogenous nitric oxide on hydroperoxide toxicity in CHP100 neuroblastoma cells.
Topics: Caffeine; Calcium; Cell Survival; Cyclic GMP; Guanylate Cyclase; Humans; Kinetics; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; tert-Butylhydroperoxide; Tumor Cells, Cultured | 1999 |
cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Coronary Vessels; Cyclic GMP; Down-Regulation; Endothelium, Vascular; Feedback; Guanylate Cyclase; Hemoglobins; Humans; Isosorbide Dinitrate; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasodilator Agents | 1999 |
Nitric oxide causes a cGMP-independent intracellular calcium rise in porcine endothelial cells-a paradox?
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; Hydrazines; Imidazoles; Intracellular Fluid; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Penicillamine; Quinoxalines; Spectrophotometry, Ultraviolet; Swine; Triazenes | 2000 |
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide.
Topics: Antigens, CD; Apoptosis; Caspase 8; Caspase 9; Caspases; Ceramides; Cyclic GMP; Enzyme Inhibitors; Humans; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Proteins; Quinoxalines; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; S-Nitroso-N-Acetylpenicillamine; Second Messenger Systems; Signal Transduction; Sphingosine; TNF Receptor-Associated Factor 1; Tumor Necrosis Factor-alpha; U937 Cells | 2000 |
Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of NO release.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cyclic GMP; Cysteine; Dibutyryl Cyclic GMP; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Glutathione; Half-Life; Kinetics; Nitric Oxide; Nitro Compounds; Oxadiazoles; PC12 Cells; Quinoxalines; Rats; Time Factors | 2000 |
Role of central glutamate receptors, nitric oxide and soluble guanylyl cyclase in the inhibition by endotoxin of rat gastric acid secretion.
Topics: Animals; Benzoates; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Glycine; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pentagastrin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solubility; Stomach; Vagotomy | 2000 |
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
Topics: Alkaloids; Animals; Arginine; Carbazoles; Cells, Cultured; Cilia; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Glutathione; Indoles; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-N-Methylarginine; Oxadiazoles; Purinones; Quinoxalines; Rats; S-Nitrosoglutathione; Signal Transduction; Trachea | 2000 |
Nitric oxide provokes tumor necrosis factor-alpha expression in adult feline myocardium through a cGMP-dependent pathway.
Topics: Animals; Benzoates; Cats; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA-Binding Proteins; Electrophoresis; I-kappa B Proteins; Imidazoles; In Vitro Techniques; Myocardium; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Phosphorylation; Protein Kinases; Quinoxalines; RNA, Messenger; Thionucleotides; Tumor Necrosis Factor-alpha | 2000 |
Nitric oxide and cGMP influence axonogenesis of antennal pioneer neurons.
Topics: Animals; Axonal Transport; Axons; Cyclic GMP; Dihydrolipoamide Dehydrogenase; Embryo, Nonmammalian; Enzyme Inhibitors; Grasshoppers; Guanylate Cyclase; Horseradish Peroxidase; Indazoles; Morphogenesis; Nervous System; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Signal Transduction | 2000 |
Cyclic GMP-independent relaxation of rat pulmonary artery by spermine NONOate, a diazeniumdiolate nitric oxide donor.
Topics: Animals; Cyclic GMP; Male; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; Spermine; Vasodilation | 2000 |
Inhibitory effect of cyclic guanosine 3',5'-monophosphate (cGMP) on the afferent resting activity in the cephalopod statocyst.
Topics: Afferent Pathways; Animals; Cyclic GMP; Cystamine; Decapodiformes; Dibutyryl Cyclic GMP; Dideoxyadenosine; Enzyme Inhibitors; Imines; Methylene Blue; Mollusca; NG-Nitroarginine Methyl Ester; Niacin; Nitroarginine; Oxadiazoles; Quinoxalines; Sense Organs | 2000 |
Nitric oxide modulates intracellular translocation of pigment organelles in Xenopus laevis melanophores.
Topics: Alkaloids; Animals; Arginine; Biological Transport; Blotting, Western; Carbazoles; Cells, Cultured; Cyclic GMP; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Guanylate Cyclase; Indoles; Melanophores; Microscopy, Fluorescence; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Signal Transduction; Time Factors; Xenopus laevis | 2000 |
Carbachol inhibits Na(+)-K(+)-ATPase activity in choroid plexus via stimulation of the NO/cGMP pathway.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cattle; Cholinergic Agonists; Choroid Plexus; Cyclic GMP; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Ouabain; Oxadiazoles; Phosphorylation; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Solubility; Thionucleotides; Triazenes; Vasodilator Agents | 2000 |
Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Oxidants; Penicillamine; Phosphodiesterase Inhibitors; Pulmonary Artery; Quinoxalines; Swine; Thionucleotides | 2001 |
Modulation of neuronal nitric oxide release by soluble guanylyl cyclase in guinea pig colon.
Topics: Animals; Arginine; Colon; Cyclic GMP; Dimethyl Sulfoxide; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Immunohistochemistry; Male; Muscle, Smooth; Neurons; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Purinones; Quinoxalines | 2001 |
Posttranscriptional regulation of human iNOS by the NO/cGMP pathway.
Topics: Cells, Cultured; Cyclic GMP; Enzyme Induction; Enzyme Inhibitors; Glomerular Mesangium; Humans; Interleukin-1; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; RNA Stability; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Effect of NO donors on protein phosphorylation in intact vascular and nonvascular smooth muscles.
Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Phosphoproteins; Phosphorylation; Quinoxalines; Rats; S-Nitroso-N-Acetylpenicillamine; Vas Deferens | 2001 |
Opposing actions of nitric oxide on synaptic inputs of identified interneurones in the central nervous system of the crayfish.
Topics: Animals; Arginine; Astacoidea; Cyclic GMP; Cyclic N-Oxides; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; Free Radical Scavengers; Ganglia, Invertebrate; Imidazoles; In Vitro Techniques; Interneurons; Male; Mechanoreceptors; Nerve Net; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Synapses; Synaptic Transmission | 2001 |
The dual effect of a nitric oxide donor in nociception.
Topics: Animals; Chronic Disease; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemoglobins; Injections, Spinal; Ligation; Male; Molsidomine; Nerve Compression Syndromes; Neuralgia; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Sciatic Nerve | 2001 |
Differential regulation of contractility and nitric oxide sensitivity in gravid and nongravid myometrium during late pregnancy in a marsupial.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Female; Gestational Age; Guanylate Cyclase; Kinetics; Marsupialia; Myometrium; Nitric Oxide; Oxadiazoles; Oxytocin; Pregnancy; Quinoxalines; Uterine Contraction | 2001 |
Signaling pathway of nitric oxide-induced acrosome reaction in human spermatozoa.
Topics: Acrosome Reaction; Aminoquinolines; Calcium; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; Male; Naphthalenes; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Protein Kinase C; Quinoxalines; Signal Transduction; Sperm Capacitation; Spermatozoa | 2001 |
The cerebrovascular response to elevated potassium--role of nitric oxide in the in vitro model of isolated rat middle cerebral arteries.
Topics: Animals; Brain Injuries; Cerebrovascular Circulation; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Male; Middle Cerebral Artery; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Organ Culture Techniques; Oxadiazoles; Penicillamine; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 2001 |
Lipid hydroperoxide and cGMP are not involved in nitric oxide inhibition of steroidogenesis in bovine granulosa cells.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Female; Granulosa Cells; Guanylate Cyclase; Lipid Peroxidation; Lipid Peroxides; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Steroids | 2000 |
Renal interstitial cGMP mediates natriuresis by direct tubule mechanism.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Arginine; Bacterial Toxins; Benzimidazoles; Consciousness; Cyclic AMP; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Female; Glomerular Filtration Rate; Kidney; Kidney Tubules; Microscopy, Fluorescence; Natriuresis; Nephrectomy; NG-Nitroarginine Methyl Ester; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Thionucleotides; Xanthenes | 2001 |
Nitric oxide induces resensitization of P2Y nucleotide receptors in cultured rat mesangial cells.
Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Glomerular Mesangium; Guanylate Cyclase; Intracellular Membranes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Oxadiazoles; Quinoxalines; Rats; Receptors, Purinergic P2; Ryanodine Receptor Calcium Release Channel | 2002 |
Effect of nitric oxide donors and noradrenaline on Ca2+ release sites and global intracellular Ca2+ in myocytes from guinea-pig small mesenteric arteries.
Topics: Animals; Calcium; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Intracellular Membranes; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Norepinephrine; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine | 2002 |
Sodium nitroprusside stimulates L-DOPA release from striatal tissue through nitric oxide and cGMP.
Topics: Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Levodopa; Male; Melatonin; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Salicylic Acid; Superoxide Dismutase; Uric Acid | 2002 |
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
Topics: Barium; Calcium; Cell Line; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Oxygen Consumption; Peroxynitrous Acid; Quinoxalines; Thapsigargin; Time Factors | 2002 |
Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Myosin Light Chains; Nitroglycerin; Norepinephrine; Oxadiazoles; Phosphorylation; Purinones; Quinoxalines; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cytosol; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucose; Hydrazines; Hypoglycemic Agents; Islets of Langerhans; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Tolbutamide | 2003 |
Nitric oxide and cyclic GMP increase the expression of matrix metalloproteinase-9 in vascular smooth muscle.
Topics: Animals; Cells, Cultured; Cyclic GMP; Cyclooxygenase 2; Isoenzymes; Lipopolysaccharides; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxadiazoles; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; RNA, Messenger; Superoxide Dismutase | 2003 |
Influence of drugs acting on nitric oxide-dependent pathways on ethanol tolerance in rats.
Topics: Aminoquinolines; Animals; Cyclic GMP; Drug Tolerance; Enzyme Inhibitors; Ethanol; Guanylate Cyclase; Male; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar | 2003 |
Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG.
Topics: Animals; Apoptosis; Carbazoles; Cell Line, Transformed; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; DNA Fragmentation; Enzyme Inhibitors; Epithelial Cells; Female; Guanylate Cyclase; Indoles; Oxadiazoles; Oxazines; Quinoxalines; Signal Transduction; Uterus | 2003 |
Evidence that nitroprusside stimulates glucose uptake in isolated rat cardiomyocytes via mitogen-activated protein kinase.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferricyanides; Flavonoids; Glucose; Imidazoles; Male; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Spermine | 2003 |
Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G.
Topics: Adrenalectomy; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Denervation; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Guanylate Cyclase; Hypertension; Ion Transport; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Natriuresis; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sodium; Soluble Guanylyl Cyclase; Thionucleotides | 2004 |
Nitric oxide activates glibenclamide-sensitive K+ channels in urinary bladder myocytes through a c-GMP-dependent mechanism.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glyburide; Guinea Pigs; Indoles; Ion Channel Gating; Male; Membrane Potentials; Molsidomine; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Potassium Channels; Quinoxalines; Signal Transduction; Urinary Bladder | 2004 |
The permissive role of endothelial NO in CO-induced cerebrovascular dilation.
Topics: Animals; Arterioles; Carbon Monoxide; Cerebral Arteries; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Nitroprusside; Oxadiazoles; Pia Mater; Potassium Channel Blockers; Quinoxalines; Swine; Tetraethylammonium; Vasodilation | 2004 |
Cytokines, nitric oxide, and cGMP modulate the permeability of an in vitro model of the human blood-brain barrier.
Topics: Blood-Brain Barrier; Capillary Permeability; Cells, Cultured; Cyclic GMP; Cytokines; Electric Impedance; Endothelial Cells; Enzyme Inhibitors; Humans; Immunohistochemistry; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxadiazoles; Quinoxalines; Signal Transduction | 2004 |
Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes.
Topics: Animals; Caffeine; Carbachol; Chelating Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Egtazic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Myocytes, Smooth Muscle; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Quinoxalines; Type C Phospholipases | 2005 |
Nitric oxide reduces T lymphocyte adhesion to human brain microvessel endothelial cells via a cGMP-dependent pathway.
Topics: Brain; Cell Adhesion; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; Humans; Intercellular Adhesion Molecule-1; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Nitroso Compounds; Oxadiazoles; Platelet Endothelial Cell Adhesion Molecule-1; Quinoxalines; Signal Transduction; T-Lymphocytes; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2005 |
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor.
Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Ouabain; Oxadiazoles; Peptides; Potassium; Quinoxalines; S-Nitrosoglutathione; Serotonin; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Triazoles | 2006 |
Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus.
Topics: Animals; Carbazoles; Cyclic GMP; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-3; Hypothalamus, Anterior; Indazoles; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Oligopeptides; Oxadiazoles; Piperidines; Quinoxalines; Rats; Suramin; Tyrosine 3-Monooxygenase | 2005 |
Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.
Topics: Animals; Cell Membrane; Cyclic GMP; Dogs; Endocardium; Endothelium; In Vitro Techniques; Muramidase; Myocardial Contraction; Myocardium; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Sepsis | 2005 |
Possible involvement of the spinal nitric oxide/cGMP pathway in vincristine-induced painful neuropathy in mice.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Injections, Spinal; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Reaction Time; Spinal Cord; Time Factors; Vincristine | 2005 |
Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation.
Topics: Adenoviridae; Animals; Calcium Signaling; Cell Line; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; Hydrazines; Hypertension, Portal; Liver; Male; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Transduction, Genetic | 2006 |
Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells.
Topics: Adenoviridae; Apoptosis; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Benzothiazoles; Caspase 3; Caspases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Guanylate Cyclase; Half-Life; Humans; Mutation; Ovarian Neoplasms; Oxadiazoles; Phosphorylation; Proto-Oncogene Proteins c-mdm2; Quinoxalines; RNA, Small Interfering; Serine; Signal Transduction; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein | 2006 |
The nitric oxide-guanosine 3',5'-cyclic monophosphate pathway regulates dopamine efflux in the medial preoptic area and copulation in male rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Copulation; Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Guanosine Monophosphate; Homovanillic Acid; Male; Microdialysis; Models, Biological; Nitric Oxide; Oxadiazoles; Preoptic Area; Quinoxalines; Rats; Rats, Long-Evans; Signal Transduction | 2006 |
Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential.
Topics: Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Hydrazines; Membrane Potentials; Mitochondria; Movement; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Prosencephalon; Quinoxalines; Rats; Time Factors | 2006 |
Nitric-oxide-dependent activation of pig oocytes: the role of the cGMP-signalling pathway.
Topics: Aminoquinolines; Animals; Cell Membrane Permeability; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Digitoxin; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Oocytes; Oxadiazoles; Penicillamine; Phosphoric Diester Hydrolases; Protein Kinase Inhibitors; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Swine | 2006 |
Cardiac mitochondrial cGMP stimulates cytochrome c release.
Topics: Animals; Apoptosis; Cells, Cultured; Cyclic GMP; Cytochromes c; Guanosine Triphosphate; Guanylate Cyclase; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar | 2007 |
Activation of the cGMP signaling pathway is essential in delaying oocyte aging in diabetes mellitus.
Topics: Animals; Cellular Senescence; Cyclic GMP; Cytoplasmic Granules; Diabetes Mellitus; Female; Mice; Microtubules; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oocytes; Oxadiazoles; Oxyhemoglobins; Protein Kinase Inhibitors; Quinoxalines; Signal Transduction; Zona Pellucida | 2006 |
Nitric oxide preconditioning regulates endothelial monolayer integrity via the heat shock protein 90-soluble guanylate cyclase pathway.
Topics: Actin Cytoskeleton; Animals; Aorta; Apoptosis; Cattle; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Impedance; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; HSP90 Heat-Shock Proteins; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Spermine; Time Factors; Wound Healing | 2007 |
CaM kinase II activation and phospholamban phosphorylation by SNP in murine gastric antrum smooth muscles.
Topics: Animals; Benzylamines; Calcium Signaling; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indoles; Mice; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Phosphorylation; Potassium Channel Blockers; Pyloric Antrum; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Soluble Guanylyl Cyclase; Sulfonamides | 2007 |
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System | 2007 |
Regulation of basolateral Cl(-) channels in airway epithelial cells: the role of nitric oxide.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amidines; Anions; Anthracenes; Benzylamines; Bestrophins; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Polarity; Chloride Channels; Cyclic GMP; Endothelial Cells; Epithelial Cells; Eye Proteins; Guanylate Cyclase; Humans; Ion Channel Gating; Lung; Macrophages, Alveolar; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; Respiratory Mucosa | 2006 |
NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes.
Topics: Animals; Cells, Cultured; Chlorides; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Flavonoids; Guanylate Cyclase; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondria, Heart; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Oxazines; Oxidation-Reduction; Penicillamine; Phosphorylation; Quinoxalines; Rats; Signal Transduction; Zinc; Zinc Compounds | 2007 |
Nitric oxide attenuates endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 in vascular smooth muscle cells by a cGMP-dependent pathway.
Topics: Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Focal Adhesion Kinase 2; Guanylate Cyclase; Hypertrophy; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Soluble Guanylyl Cyclase | 2007 |
Phosphodiesterase type 5 inhibition coupled to strong reinforcement results in two periods of transient retention loss in the young chick.
Topics: Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Chickens; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Memory Disorders; Phosphodiesterase 5 Inhibitors; Purinones; Quinoxalines; Reinforcement, Psychology; Retention, Psychology; Time Factors | 2007 |
Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP.
Topics: Animals; Anisomycin; Brain Diseases; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Ischemic Preconditioning; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxadiazoles; Protein Synthesis Inhibitors; Quinoxalines | 2007 |
NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel.
Topics: Adult; Aged; Aged, 80 and over; Animals; Aqueous Humor; Cell Line; Cell Size; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Guanylate Cyclase; Humans; Intraocular Pressure; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Microscopy, Confocal; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Osmolar Concentration; Oxadiazoles; Peptides; Perfusion; Potassium Channel Blockers; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine; Thionucleotides; Time Factors; Tissue Culture Techniques; Trabecular Meshwork | 2008 |
Involvement of soluble guanylate cyclase alpha(1) and alpha(2), and SK(Ca) channels in NANC relaxation of mouse distal colon.
Topics: Animals; Apamin; Blotting, Western; Colon; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanylate Cyclase; Male; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Potassium Channel Blockers; Protein Subunits; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Small-Conductance Calcium-Activated Potassium Channels; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide | 2008 |
Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2.
Topics: Adenocarcinoma; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cell Survival; Cyclic GMP; Enzyme Inhibitors; Fluorescent Antibody Technique; Grape Seed Extract; Guanylate Cyclase; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Plant Extracts; Proanthocyanidins; Quinoxalines; Receptors, Cell Surface; Signal Transduction; Tumor Cells, Cultured; Vitis | 2009 |
cGMP-independent anti-apoptotic effect of nitric oxide on thapsigargin-induced apoptosis in the pancreatic beta-cell line INS-1.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Flow Cytometry; Insulin-Secreting Cells; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; Rats; Thapsigargin; Triazenes | 2008 |
Human trabecular meshwork cell volume decrease by NO-independent soluble guanylate cyclase activators YC-1 and BAY-58-2667 involves the BKCa ion channel.
Topics: Adult; Aged; Aged, 80 and over; Benzoates; Cell Size; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Guanylate Cyclase; Humans; Indazoles; Large-Conductance Calcium-Activated Potassium Channels; Microscopy, Confocal; Nitric Oxide; Oxadiazoles; Quinoxalines; Trabecular Meshwork | 2009 |
Sustained elevation of cyclic guanosine monophosphate induces apoptosis in microglia.
Topics: Animals; Apoptosis; Cell Death; Cell Line; Cell Membrane; Cell Nucleus; Cells, Cultured; Chromatin; Cyclic GMP; Enzyme Inhibitors; Intracellular Space; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Nitrites; Oxadiazoles; Phosphatidylserines; Quaternary Ammonium Compounds; Quinoxalines | 2009 |
Complex interactions of NO/cGMP/PKG systems on Ca2+ signaling in afferent arteriolar vascular smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; ADP-ribosyl Cyclase; Animals; Arterioles; Calcium; Calcium Signaling; Carbazoles; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Peptides; Phosphodiesterase Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley | 2010 |
Protein kinase G type-Ialpha phosphorylates the apoptosis-regulating protein Bad at serine 155 and protects against apoptosis in N1E-115 cells.
Topics: Apoptosis; bcl-Associated Death Protein; Blotting, Western; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; DNA Fragmentation; Enzyme Activation; Humans; Nitric Oxide; Oxadiazoles; Phosphorylation; Quinoxalines; Recombinant Proteins; Serine | 2010 |
Propyretic role of the locus coeruleus nitric oxide pathway.
Topics: Animals; Cyclic GMP; Endotoxins; Fever; Guanylate Cyclase; Locus Coeruleus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2010 |
Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Lung; Myosin-Light-Chain Phosphatase; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Protein Isoforms; Protein Phosphatase 1; Pulmonary Artery; Quinoxalines; Swine; Triazenes; Vasoconstrictor Agents | 2010 |
Nitric oxide in the control of luminescence from lantern shark (Etmopterus spinax) photophores.
Topics: Animal Structures; Animals; Cyclic GMP; Embryo, Nonmammalian; Enzyme Inhibitors; Guanylate Cyclase; Hydroxylamine; Immunohistochemistry; Luminescence; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Quinoxalines; Sharks; Signal Transduction; Spectrum Analysis | 2010 |
Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.
Topics: Animals; Cricetinae; Cyclic GMP; Ileum; Male; Membrane Potentials; Mesocricetus; Myocytes, Smooth Muscle; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Substance P; Tachykinins | 2011 |
Cirrhosis decreases vasoconstrictor response to electrical field stimulation in rat mesenteric artery: role of calcitonin gene-related peptide.
Topics: Animals; ATP-Binding Cassette Transporters; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcitonin Receptor-Like Protein; Carbon Tetrachloride; Cyclic GMP; Electric Stimulation; Glyburide; KATP Channels; Liver Cirrhosis; Male; Mesenteric Arteries; Muscle Cells; Oxadiazoles; Peptide Fragments; Pinacidil; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Protein 1; Receptors, Calcitonin Gene-Related Peptide; Receptors, Drug; Sulfonylurea Receptors; Vasoconstriction; Vasodilation | 2011 |
Activity of guanylyl cyclase activators on the reaction of tracheal smooth muscle contraction.
Topics: Animals; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Female; Guanylate Cyclase; Indazoles; Male; Muscle, Smooth; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Trachea | 2011 |
Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways.
Topics: Adenosine Triphosphate; Adult; Aged; Amiloride; Bronchi; Chloride Channels; Colforsin; Cyclic GMP; Cyclic N-Oxides; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Free Radical Scavengers; Guanylate Cyclase; Humans; Imidazoles; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Purinones; Quinoxalines; Young Adult | 2012 |
Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility.
Topics: Adult; Cell Physiological Phenomena; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Guanylate Cyclase; Humans; Infant; Middle Aged; Myosin Light Chains; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Phosphorylation; Quinoxalines; Tissue Donors; Trabecular Meshwork; Triazenes | 2014 |
The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dermis; Enzyme Inhibitors; Fibroblasts; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Quinoxalines; Signal Transduction; Toxins, Biological; Wound Healing | 2014 |
Nitric oxide augments single Ca(2+) channel currents via cGMP-dependent protein kinase in Kenyon cells isolated from the mushroom body of the cricket brain.
Topics: Action Potentials; Animals; Brain; Calcium Channels; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gryllidae; Male; Mushroom Bodies; Neurons; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; Signal Transduction | 2015 |