quinoxalines has been researched along with 4-aminopyridine in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.54) | 18.7374 |
| 1990's | 28 (43.08) | 18.2507 |
| 2000's | 22 (33.85) | 29.6817 |
| 2010's | 14 (21.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avoli, M; Psarropoulou, C | 2 |
| Banks, MI; Smith, PH | 1 |
| Bijak, M; Brunner, H; Dembowsky, K; Misgeld, U | 1 |
| Aram, JA; Michelson, HB; Wong, RK | 1 |
| Benishin, C; Fredholm, BB; Hu, PS | 1 |
| Kessler, M; Lynch, G; Staubli, U; Xiao, P | 1 |
| Gean, PW | 1 |
| Chang, FC; Chou, SM; Gean, PW | 1 |
| Fredholm, BB; Hu, PS | 1 |
| Jahr, CE; Tong, G | 1 |
| Boeckxstaens, GE; De Man, JG; Herman, AG; Pelckmans, PA | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Donevan, SD; Rogawski, MA; Yamaguchi, S | 1 |
| Avoli, M; Fueta, Y; Psarropoulou, C; Tancredi, V | 1 |
| Bijak, M; Misgeld, U | 1 |
| Avoli, M; Kurcewicz, I; Louvel, J; Pumain, R | 1 |
| Lev-Tov, A; Pinco, M | 1 |
| Avoli, M; Hwa, GG; Mattia, D | 1 |
| Bijak, M; Demmelhuber, J; Jarolimek, W; Misgeld, U | 1 |
| Dolezal, V; Hertting, G; Huang, HY; Schobert, A | 1 |
| Malenka, RC; Nicoll, RA; Salin, PA; Scanziani, M | 1 |
| Kaila, K; Lamsa, K | 1 |
| Akaike, N; Arima, J; Ishibashi, H; Kubo, C | 1 |
| Carvalho, AP; Carvalho, CM; Sequeira, SM | 1 |
| Dierkes, PW; Müller, M; Schlue, WR | 1 |
| Faraci, FM; Sobey, CG | 1 |
| Bryan, RM; Johnson, TD; Marrelli, SP; Mombouli, JV; You, J | 1 |
| Strowbridge, BW | 1 |
| Gordon, JB; Halla, TR; Madden, JA | 1 |
| Cole, WC; Dong, H; Jiang, Y; Triggle, CR | 1 |
| Garland, CJ; Plane, F; Sampson, LJ; Smith, JJ | 1 |
| Gray, R; Johnston, D; Liang, Y; Yuan, LL | 1 |
| Alger, B; Brager, D; Lenz, RA; London, B; Morishita, W; Varma, N | 1 |
| Ishikawa, T; Kaneko, Y; Nakayama, K; Sugino, F | 1 |
| Christie, JM; Westbrook, GL | 1 |
| Ayala, GX; Tapia, R | 1 |
| Grebenyuk, S; Kirichok, Y; Krishtal, O; Lozovaya, N; Melnik, S; Tsintsadze, T | 1 |
| Fritschy, JM; Marty, S; Sotelo, C; Wehrlé, R | 1 |
| Liu, X; Stan Leung, L | 1 |
| Brown, JT; Collingridge, GL; Davies, CH; Randall, AD; Richardson, JC | 1 |
| Fujii, S; Hozumi, Y; Kaneko, K; Kato, H; Kudo, Y; Li, J; Miyakawa, H; Yamazaki, Y | 1 |
| Chu, V; Janssen, LJ; Tazzeo, T; Zhang, Y | 1 |
| Breschi, MC; Calderone, V; Martelli, A; Martinotti, E; Testai, L | 1 |
| Hammack, SE; Mania, I; Rainnie, DG | 1 |
| Baggio, CH; Cipriani, TR; da Silva-Santos, JE; de Souza, LM; Freitas, CS; Graça, C; Marques, MC; Pontarolo, R; Rattmann, YD; Rieck, L; Sassaki, GL | 1 |
| Andresen, MC; Appleyard, SM; Kobayashi, K; Low, MJ; Marks, D; Okano, H | 1 |
| Chen, J; Chen, X; Liu, J; Wang, T; Xiao, H; Yang, J; Ye, Z; Yin, C | 1 |
| Favaloro, JL; Kemp-Harper, BK | 1 |
| Avoli, M; de Curtis, M; Uva, L | 1 |
| Sun, QQ | 1 |
| He, XH; Justice, JA; Peng, BW; Sanchez, RM; Zhang, K | 1 |
| Avoli, M; Carriero, G; de Curtis, M; Gnatkovsky, V; Uva, L | 1 |
| Bean, BP; Milescu, LS; Smith, JC | 1 |
| Aaronson, PI; Knock, GA; Kua, J; Smirnov, SV; Snetkov, VA; Ward, JP | 1 |
| Canning, BJ; Mori, N | 1 |
| Avoli, M; Dzakpasu, R; Gonzalez-Sulser, A; Motamedi, GK; Vicini, S; Wang, J | 1 |
| Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM | 1 |
| Chavis, P; Farrugia, F; Garenne, A; Le Masson, G; Manzoni, OJ; Marsicano, G; Piet, R | 1 |
| Bae, H; Bang, H; Kim, JH; Kim, K; Kim, T; Ko, JH; Lee, HJ; Lim, I | 1 |
| Breschi, GL; de Curtis, M; Gnatkovsky, V; Taverna, S; Uva, L | 1 |
| Carter, RE; Chen, G; Cramer, SW; Ebner, TJ; Popa, LS | 1 |
| Avoli, M; Hamidi, S; Herrington, R; Lévesque, M | 1 |
| Fontanini, A; Haley, MS; Maffei, A | 1 |
| Green, DB; Grimsley, CA; Sivaramakrishnan, S | 1 |
65 other study(ies) available for quinoxalines and 4-aminopyridine
| Article | Year |
|---|---|
CPP, an NMDA-receptor antagonist, blocks 4-aminopyridine-induced spreading depression episodes but not epileptiform activity in immature rat hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Anticonvulsants; Dendrites; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Models, Biological; Piperazines; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Intracellular recordings from neurobiotin-labeled cells in brain slices of the rat medial nucleus of the trapezoid body.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Biotin; Cochlear Nerve; Electric Conductivity; In Vitro Techniques; Male; Membrane Potentials; Nerve Fibers; Neurons; Pons; Quinoxalines; Rats; Rats, Inbred Strains; Strychnine | 1992 |
K-dependent inhibition in the dentate-CA3 network of guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Cytoplasmic Granules; Guinea Pigs; Hippocampus; Histocytochemistry; Horseradish Peroxidase; In Vitro Techniques; Membrane Potentials; Nerve Net; Neurons; Potassium; Quinoxalines; Synaptic Transmission | 1992 |
Synchronized GABAergic IPSPs recorded in the neocortex after blockade of synaptic transmission mediated by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Picrotoxin; Quinoxalines; Synapses; Synaptic Transmission | 1991 |
Comparison of the effects of four dendrotoxin peptides, 4-aminopyridine and tetraethylammonium on the electrically evoked [3H]noradrenaline release from rat hippocampus.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Binding, Competitive; Brimonidine Tartrate; Clonidine; Elapid Venoms; Electric Stimulation; Hippocampus; Male; Norepinephrine; Peptide Fragments; Peptides; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetraethylammonium; Tetraethylammonium Compounds; Tritium | 1991 |
Selective effects of aniracetam across receptor types and forms of synaptic facilitation in hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Hippocampus; Hydroxybenzoate Ethers; Hydroxybenzoates; Long-Term Potentiation; Pyrrolidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Transmission | 1991 |
The epileptiform activity induced by 4-aminopyridine in rat amygdala slices: antagonism by non-N-methyl-D-aspartate receptor antagonists.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Electrophysiology; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Epileptiform activity induced by 4-aminopyridine in rat amygdala neurons: the involvement of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Electric Stimulation; Epilepsy; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Alpha 2-adrenoceptor agonist-mediated inhibition of [3H]noradrenaline release from rat hippocampus is reduced by 4-aminopyridine, but that caused by an adenosine analogue or omega-conotoxin is not.
Topics: 4-Aminopyridine; Adenosine; Adrenergic alpha-Agonists; Aminopyridines; Animals; Brimonidine Tartrate; Cadmium; Cadmium Chloride; Conotoxins; Hippocampus; Male; Mollusk Venoms; Norepinephrine; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Effect of potassium channel blockade and alpha 2-adrenoceptor activation on the release of nitric oxide from non-adrenergic non-cholinergic nerves.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Arginine; Autonomic Nervous System; Brimonidine Tartrate; Charybdotoxin; Dogs; Electric Stimulation; Female; Male; Nitric Oxide; Nitroarginine; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Tetraethylammonium Compounds; Tetrodotoxin; Yohimbine | 1994 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Kainic Acid; Male; Mice; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 1993 |
On the synchronous activity induced by 4-aminopyridine in the CA3 subfield of juvenile rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Culture Techniques; Evoked Potentials; Hippocampus; Neuroglia; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA; Synaptic Transmission | 1993 |
Role of glutamatergic synaptic transmission in synchronized discharges of hilar neurons in guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Quinoxalines; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Time Factors | 1993 |
Extracellular free potassium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electrophysiology; Extracellular Space; Hippocampus; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
4-Aminopyridine-induced spreading depression episodes in immature hippocampus: developmental and pharmacological characteristics.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cortical Spreading Depression; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1993 |
Synaptic excitation of alpha-motoneurons by dorsal root afferents in the neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Animals, Newborn; Ganglia, Spinal; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
Epileptiform activity induced by 4-aminopyridine in guinea-pig and rat neocortices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cerebral Cortex; Electric Stimulation; Electrophysiology; Epilepsy; Guinea Pigs; In Vitro Techniques; Piperazines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses | 1993 |
3,4-Diaminopyridine masks the inhibition of noradrenaline release from chick sympathetic neurons via presynaptic alpha 2-adrenoceptors: insights into the role of N- and L-type calcium channels.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Amifampridine; Animals; Brimonidine Tartrate; Calcium Channels; Cells, Cultured; Chick Embryo; Electric Stimulation; Fluorescent Dyes; Fluorometry; Fura-2; Neurons; Norepinephrine; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Sympathetic Nervous System | 1996 |
Distinct short-term plasticity at two excitatory synapses in the hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Nerve Fibers; Neuronal Plasticity; Neurons; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1996 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
alpha2-Adrenoceptor-mediated potassium currents in acutely dissociated rat locus coeruleus neurones.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane Permeability; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoquinolines; Kinetics; Locus Coeruleus; Membrane Potentials; Neurons; Nystatin; Patch-Clamp Techniques; Piperazines; Potassium; Potassium Channel Blockers; Potassium Channels; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Thionucleotides; Yohimbine | 1998 |
Both protein kinase G dependent and independent mechanisms are involved in the modulation of glutamate release by nitric oxide in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Nitric Oxide; Nitroprusside; Oxadiazoles; Presynaptic Terminals; Protein Kinases; Quinoxalines; Rats; Sulfhydryl Reagents; Synaptosomes; Thionucleotides | 1999 |
Ionic mechanism of 4-aminopyridine action on leech neuropile glial cells.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Calcium; Cell Communication; Chlorides; Dose-Response Relationship, Drug; Electric Impedance; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Leeches; Membrane Potentials; Muscle Relaxants, Central; Neuroglia; Neurons; Neuropil; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium; Potassium Channels; Quinine; Quinoxalines; Sodium; Synaptic Transmission; Tetraethylammonium; Tubocurarine | 1999 |
Inhibitory effect of 4-aminopyridine on responses of the basilar artery to nitric oxide.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Animals; Basilar Artery; Cromakalim; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Papaverine; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1999 |
P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats.
Topics: 4-Aminopyridine; Animals; Apamin; Barium Compounds; Cerebral Arteries; Cerebrovascular Circulation; Charybdotoxin; Chlorides; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Channels; Potassium Chloride; Quinoxalines; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Tetraethylammonium; Uridine Triphosphate; Vasodilation | 1999 |
Glutamate receptors mediate TTX-resistant synchronous activity in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Axons; Drug Resistance; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Neurons; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium; Sodium Channels; Synapses; Synaptic Transmission; Tetraethylammonium; Tetrodotoxin | 1999 |
Mediators of alkalosis-induced relaxation of piglet pulmonary veins.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Alkalosis; Animals; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Nitric Oxide; Nitroarginine; Oxadiazoles; Peptides; Potassium Channels; Pulmonary Veins; Quinoxalines; Swine; Vasoconstrictor Agents; Vasodilation | 2000 |
Comparison of the pharmacological properties of EDHF-mediated vasorelaxation in guinea-pig cerebral and mesenteric resistance vessels.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Arachidonic Acids; Biological Factors; Cerebral Arteries; Charybdotoxin; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Ouabain; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Vasodilation; Vasodilator Agents | 2000 |
Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.
Topics: 4-Aminopyridine; Animals; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Peptides; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Vasodilation | 2001 |
Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Signaling; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Indoles; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Thapsigargin | 2002 |
Presynaptic factors in the regulation of DSI expression in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Male; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Signal Transduction; Tetraethylammonium; Tetrodotoxin | 2002 |
Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cytosol; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucose; Hydrazines; Hypoglycemic Agents; Islets of Langerhans; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Tolbutamide | 2003 |
Regulation of backpropagating action potentials in mitral cell lateral dendrites by A-type potassium currents.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Axons; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2003 |
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors | 2003 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Quantitative effects produced by modifications of neuronal activity on the size of GABAA receptor clusters in hippocampal slice cultures.
Topics: 4-Aminopyridine; Age Factors; Animals; Animals, Newborn; Bicuculline; Cell Count; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Neural Inhibition; Neurons; Organ Culture Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 2004 |
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lithium; Male; Neural Conduction; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2004 |
Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice.
Topics: 4-Aminopyridine; Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cortical Synchronization; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Synaptic Transmission | 2005 |
Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.
Topics: 4-Aminopyridine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Cell Communication; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Tetraethylammonium; Theophylline | 2005 |
Membrane potassium currents in human radial artery and their regulation by nitric oxide donor.
Topics: 4-Aminopyridine; Adult; Aged; Aged, 80 and over; Blotting, Western; Female; Glyburide; Guanylate Cyclase; Humans; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Penicillamine; Peptides; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Quinoxalines; Radial Artery; Tetraethylammonium Compounds | 2006 |
Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2007 |
Differential expression of intrinsic membrane currents in defined cell types of the anterolateral bed nucleus of the stria terminalis.
Topics: 4-Aminopyridine; Aging; Animals; Benzylamines; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Quinoxalines; Rats; Septal Nuclei; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2007 |
In vivo assessment of safety and mechanisms underlying in vitro relaxation induced by Mikania laevigata Schultz Bip. ex Baker in the rat trachea.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Brazil; Coumarins; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glyburide; In Vitro Techniques; Male; Mice; Mikania; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Oxadiazoles; Plant Extracts; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Toxicity Tests, Acute; Toxicity Tests, Chronic; Trachea | 2007 |
Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.
Topics: 4-Aminopyridine; Afferent Pathways; Analysis of Variance; Animals; Catecholamines; Cholecystokinin; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridazines; Quinoxalines; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2007 |
The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.
Topics: 4-Aminopyridine; Animals; Benzylisoquinolines; Drugs, Chinese Herbal; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Nitroarginine; Oxadiazoles; Penis; Potassium Channel Blockers; Potassium Chloride; Quinoxalines; Rabbits; Stephania tetrandra; Tetraethylammonium | 2009 |
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cortical Spreading Depression; Cortical Synchronization; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Inhibitory Postsynaptic Potentials; Limbic System; Neurons; Olfactory Pathways; Organ Culture Techniques; Potassium Channel Blockers; Quinoxalines; Receptors, GABA; Valine | 2009 |
Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Biotin; Cerebral Cortex; Computer Simulation; Electric Stimulation; Electron Transport Complex IV; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Transgenic; Models, Neurological; Neuronal Plasticity; Parvalbumins; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Probability; Quinoxalines; Sensory Deprivation; Synaptic Transmission; Vesicular Glutamate Transport Protein 2; Vibrissae | 2009 |
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Biophysics; CA1 Region, Hippocampal; Cadmium Chloride; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lamotrigine; Lysine; Male; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Tetraethylammonium; Triazines; Valine | 2010 |
Independent epileptiform discharge patterns in the olfactory and limbic areas of the in vitro isolated Guinea pig brain during 4-aminopyridine treatment.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Brain; Cerebral Cortex; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Limbic System; Periodicity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors | 2010 |
Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Axons; Biophysical Phenomena; Brain; Cadmium Chloride; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Models, Neurological; Motor Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetraethylammonium | 2010 |
Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Aminoquinolines; Animals; Calcium Signaling; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Myocytes, Smooth Muscle; Oxadiazoles; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pulmonary Artery; Quinoxalines; Rats; Rats, Wistar; rho-Associated Kinases; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citric Acid; Cough; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mechanoreceptors; Propionates; Quinoxalines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Recurrent Laryngeal Nerve; Reflex; Respiratory Mucosa; Sensory Receptor Cells; Solitary Nucleus; Substance P; Trachea; Vagus Nerve; Valine | 2011 |
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex | 2011 |
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents | 2011 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways.
Topics: 4-Aminopyridine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dermis; Enzyme Inhibitors; Fibroblasts; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Nitric Oxide; Oxadiazoles; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Quinoxalines; Signal Transduction; Toxins, Biological; Wound Healing | 2014 |
Synchronous inhibitory potentials precede seizure-like events in acute models of focal limbic seizures.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Computer Simulation; Convulsants; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; In Vitro Techniques; Models, Biological; Neural Inhibition; Potassium Channel Blockers; Quinoxalines; Seizures | 2015 |
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Cortex; Channelopathies; Cortical Synchronization; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Transgenic; Mutation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Potassium Channel Blockers; Pyridines; Quinoxalines; Vibrissae | 2015 |
Interneurons spark seizure-like activity in the entorhinal cortex.
Topics: 4-Aminopyridine; Action Potentials; Animals; Disease Models, Animal; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Interneurons; Male; Piperazines; Quinoxalines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques | 2016 |
Laminar- and Target-Specific Amygdalar Inputs in Rat Primary Gustatory Cortex.
Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Amygdala; Animals; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Male; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Sensorimotor Cortex; Sodium Channel Blockers; Taste; Tetrodotoxin | 2016 |
L-type calcium channels refine the neural population code of sound level.
Topics: 4-Aminopyridine; Acoustic Stimulation; Action Potentials; Amifampridine; Animals; Biophysical Phenomena; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inferior Colliculi; Mice; Mice, Inbred CBA; Neurons; Nimodipine; omega-Conotoxin GVIA; Potassium Channel Blockers; Quinoxalines; Sound; Wakefulness | 2016 |