quinoxalines has been researched along with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline in 1165 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 449 (38.54) | 18.2507 |
| 2000's | 462 (39.66) | 29.6817 |
| 2010's | 242 (20.77) | 24.3611 |
| 2020's | 12 (1.03) | 2.80 |
| Authors | Studies |
|---|---|
| Cox, JA; Seeburg, PH; Stein, E; Verdoorn, TA | 1 |
| Kunow, M; Löschmann, PA; Wachtel, H | 2 |
| Boddeke, HW; Massieu, L; Mengod, G; Palacios, JM; Rocamora, N | 2 |
| Nellgård, B; Wieloch, T | 3 |
| Hansen, AJ; Lauritzen, M | 1 |
| Choiniere, D; Mundt, DJ; Teng, YD; Wrathall, JR | 1 |
| Diemer, NH; Honoré, T; Johansen, FF; Jørgensen, MB; Sheardown, M | 1 |
| Lodge, D; Palmer, AJ; Zeman, S | 1 |
| Lees, GJ; Leong, W | 4 |
| McFarlane, C; Nordholm, L; Todd, MM; Warner, DS | 1 |
| Chapman, AG; Craggs, MD; Dürmüller, N; Meldrum, BS; Smith, SE | 1 |
| Fink-Jensen, A; Hansen, JB; Honoré, T; Jacobsen, P; Judge, ME; Olney, J; Turski, L | 1 |
| Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C | 2 |
| Jönsson, T; Lehmann, A | 1 |
| Johansson, BB; Westergren, I | 3 |
| Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH | 1 |
| Pai, KS; Ravindranath, V | 1 |
| Honoré, T; Jacobsen, P; Stephens, DN; Turski, L | 1 |
| Parks, TN; Zhou, N | 2 |
| Lodge, D; Zeman, S | 1 |
| Cordi, A; Guet, T; Lepagnol, JM; Randle, JC | 1 |
| Bruhn, T; Diemer, NH; Frank, L | 2 |
| Balchen, T; Diemer, NH | 1 |
| East, SJ; Garthwaite, J | 1 |
| Taylor, CP; Vartanian, MG | 1 |
| Gill, R; Lodge, D; Nordholm, L | 1 |
| Albrecht, RF; Hoffman, WE; Kochs, E; Pelligrino, D; Schulte am Esch, J; Werner, C | 1 |
| Buchan, AM; Huang, ZG; Lesiuk, H; Smith, KH; Xue, D | 1 |
| Castrén, E; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Gash, DM; Greenamyre, JT; Honoré, T; Klockgether, T; Kurlan, R; Turski, L; Zhang, ZM | 1 |
| Buchan, AM; Cho, S; Li, H; Pulsinelli, WA | 1 |
| Lund, A; Olsen, UB | 1 |
| Honoré, T; Jacobsen, P; Judge, ME; Sheardown, MJ | 1 |
| Gillis, RA; Rossiter, CD; Travagli, RA; Vicini, S | 1 |
| Dürmüller, N; Meldrum, BS; Smith, SE | 1 |
| Bengzon, J; Ernfors, P; Kokaia, Z; Lindvall, O; Persson, H; Siesjö, BK; Smith, ML | 1 |
| Bang, L; Mellemkjaer, S; Nielsen-Kudsk, F | 1 |
| Nordholm, L | 1 |
| Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| Ikonomidou, C; Sieklucka, M; Turski, WA; Urbańska, E | 1 |
| Bengzon, J; Ernfors, P; Kokaia, Z; Lindvall, O; Persson, H | 1 |
| Honoré, T; Jähnig, P; Jenner, P; Kunow, M; Lange, KW; Löschmann, PA; Marsden, CD; Rettig, KJ; Turski, L; Wachtel, H | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Empson, RM; Gloveli, T; Heinemann, U; Schmitz, D | 2 |
| Sheardown, MJ | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Browne, SE; Bullock, R; Dawson, D; Fujisawa, H; MacKay, KB; McCulloch, J | 1 |
| Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL | 1 |
| Barnes, K; Buchan, AM; Huang, ZG; Lesiuk, HJ; Smith, KE; Xue, D | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Brooker, G; Costa, E; de Erausquin, G; Hanbauer, I | 1 |
| Lookingland, KJ; Moore, KE; Wagner, EJ | 2 |
| Akgören, N; Fabricius, M; Lauritzen, M | 1 |
| Massieu, L; Tapia, R | 1 |
| Chizh, BA; Cumberbatch, MJ; Headley, PM | 2 |
| Gruner, R; Parsons, CG; Rozental, J | 1 |
| Greenamyre, JT; Greene, JG | 2 |
| Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E | 2 |
| Miller, RF; Yu, W | 4 |
| Farfel, GM; Seiden, LS | 1 |
| Greenamyre, JT; Porter, RH | 1 |
| Andersen, PH; Jørgensen, M; Tygesen, CK | 1 |
| Bianchi, L; Camilli, F; Colivicchi, MA; Giovannini, MG; Mundula, A; Pepeu, G | 1 |
| Hoff, P; Tegtmeier, F; Xie, Y; Zacharias, E | 1 |
| Balázs, R; Hack, N | 1 |
| Drejer, J; Johansen, TH; Nielsen, EO; Wätjen, F | 2 |
| Abe, S; Akazawa, K; Nakamura, M | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Karius, DR; Speck, DF | 1 |
| Brasko, J; Patrikios, P; Ross, DT | 1 |
| Hayabara, T; Kuroda, S; Morimoto, K; Sato, K; Yamada, N | 1 |
| Alvarado, S; Blume, H; Firkusny, I; Geary, C; Jensen, FE | 1 |
| Karcz-Kubicha, M; Liljequist, S | 1 |
| Honoré, T; Jacobsen, P; Swedberg, MD | 1 |
| Beaver, KM; Hawkins, LM; Jane, DE; Roberts, PJ; Sunter, DC; Taylor, PM | 1 |
| McCulloch, J; Patel, TR | 1 |
| Kubová, H; Mares, P; Vachová, D; Velísek, L | 1 |
| Hansen, AJ | 1 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M; Verrecchia, C | 1 |
| Hatton, GI; Smithson, KG; Yang, QZ | 1 |
| Batchelor, AM; Garthwaite, J | 1 |
| Lodge, D; Palmer, AJ | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Kelland, MD | 1 |
| French, ED; Wang, T | 1 |
| Guillén, J; Laguna, J; Luquin, MR; Martínez-Lage, JM; Obeso, JA | 1 |
| Honoré, T; Sheardown, MJ; Suzdak, PD | 1 |
| Nordholm, L; Sheardown, MJ; Suzdak, PD | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Buchan, AM; Li, H | 1 |
| Hammerland, LG; Parks, TN; Zhou, N | 1 |
| Donevan, SD; Rogawski, MA; Yamaguchi, S | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, WA; Zarnowski, T | 1 |
| Bau, A; Faarup, P; Foged, C; Kanstrup, A; Suzdak, PD; Thomsen, C | 1 |
| Bolton, PS; Walmsley, B | 1 |
| Benz, A; Mennerick, S; Que, J; Zorumski, CF | 1 |
| De Sarro, A; De Sarro, G; Nava, F; Renne, S | 1 |
| Massieu, L; Morales-Villagrán, A; Tapia, R | 1 |
| Mennerick, S; Zorumski, CF | 1 |
| Choi, DW; Gwag, BJ; Koh, JY; Lobner, D | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Croucher, MJ; Patel, DR; Sturt, NJ | 1 |
| Barnabei, O; Contestabile, A; Virgili, M | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Gaspary, HL; Graham, SH; Simon, RP | 1 |
| Bertolino, M; Costa, E; DiBella, M; Guidotti, A; Thompson, DM; Uzunov, D; Zivkovic, I | 1 |
| Beart, PM; Ganakas, AM; Mercer, LD; Shinozaki, H | 1 |
| Anderson, JJ; Chase, TN; Kuo, S | 1 |
| Starr, BS; Starr, MS | 2 |
| Andiné, P; Diemer, NH; Gilland, E; Hagberg, H | 1 |
| Folbergrová, J | 2 |
| Hansen, KT | 1 |
| Baubichon, D; Blanchet, G; Burckhart, MF; Carpentier, P; Lallement, G; Pernot-Marino, I | 1 |
| Djuricic, B; Hossmann, KA; Kohno, K; Mies, G | 1 |
| Baumgartner, WA; Blue, ME; Cameron, DE; Gillinov, AM; Johnston, MV; Lange, MS; Redmond, JM; Troncoso, JC; Zehr, KJ | 1 |
| Hönack, D; Löscher, W | 2 |
| Dimpfel, W | 1 |
| Pai, KS; Ravindranath, V; Shankar, SK | 1 |
| Witkin, JM | 1 |
| Hagberg, H; Lehmann, A; Orwar, O; Sandberg, M | 1 |
| Hönack, D; Löscher, W; Rundfeldt, C | 1 |
| Boysen, G; Overgaard, K; Pedersen, H; Sereghy, T | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, P; Xu, Y; Yang, GY | 1 |
| Schmidt, WJ; Zadow, B | 1 |
| Heinemann, U; Kral, T; Luhmann, HJ | 1 |
| Krieglstein, J; Lippert, K; Welsch, M | 1 |
| Karius, DR; Ling, L; Speck, DF | 1 |
| Cheron, G; Godaux, E; Mettens, P | 2 |
| Holmberg, L; Seiger, A; Sundström, E; von Euler, M | 1 |
| Lindsay, AD; Weiss, JH; Yin, HZ | 1 |
| Dragunow, M; Young, D | 2 |
| Metsis, M; Timmusk, T | 1 |
| Choiniere, D; Teng, YD; Wrathall, JR | 2 |
| Hunter, JC; Singh, L | 1 |
| Chan, PH; Chang, LH; Espanol, MT; James, TL; Litt, L; Weinstein, PR; Xu, Y | 1 |
| McEwen, BS; Woolley, CS | 1 |
| Baubichon, D; Blanchet, G; Carpentier, P; Foquin-Tarricone, A; Lallement, G; Pernot-Marino, I; Piras, A | 2 |
| Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Anderson, JJ; Boldry, RC; Chase, TN; Engber, TM; Kuo, S; Papa, SM | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Browne, SE; McCulloch, J | 1 |
| Penix, LP; Wasterlain, CG | 1 |
| Hossmann, KA; Kohno, K; Mies, G | 1 |
| Canella, R; Comelli, MC; Guidolin, D; Manev, H; Rubini, R; Seren, MS; Zanoni, R | 1 |
| Brugger, F; Clark, KC; Evans, RH; Hawkins, NS; Pook, P; Watkins, JC | 1 |
| Greenamyre, JT | 1 |
| al-Zubaidy, ZA; Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| DeGraba, TJ; Grotta, JC; Hanson, S; Ostrow, P | 1 |
| Pellegrini-Giampietro, DE; Pulsinelli, WA; Zukin, RS | 1 |
| Berg, M; Bruhn, T; Diemer, NH; Johansen, FF | 1 |
| Furuya, T; Hidaka, K; Kawasaki, S; Kubota, H; Murase, K; Ohmori, J; Okada, M; Sakamoto, S; Shimizu-Sasamata, M; Togami, J | 1 |
| Bagetta, G; Dolly, JO; Nair, S; Nistico, G | 1 |
| Dretchen, KL; Gillis, RA; McManigle, JE; Taveira DaSilva, AM | 1 |
| Chen, K; Dretchen, KL; Gillis, RA; Hernandez, YM | 1 |
| Haraldseth, O; Müller, TB; Petersen, SB; Sonnewald, U; Unsgård, G | 1 |
| Craggs, M; Dürmüller, N; Meldrum, BS | 1 |
| Kuroda, S; Morimoto, K; Namba, T; Sato, K; Yamada, N | 1 |
| Hao, JX; Seiger, A; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Cerne, R; Jiang, MC; Randić, M | 1 |
| Dall, V; Nordholm, L; Orntoft, U; Schmidt, A | 1 |
| Aoki, M; Fackler, JC; Hickey, PR; Holtzman, D; Jonas, RA; Nomura, F; Stromski, ME; Tsuji, MK | 1 |
| Cotman, CW; Pike, CJ; Weiss, JH | 1 |
| Boysen, G; Meden, P; Overgaard, K; Sereghy, T | 1 |
| Steppuhn, KG; Turski, L | 1 |
| Christensen, T; Diemer, NH; Jørgensen, MB | 1 |
| Löscher, W; Löschmann, PA; Richter, A | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Papa, SM | 1 |
| Birrell, GJ; Marcoux, FW | 1 |
| Baubichon, D; Blanchet, G; Carpentier, P; Delamanche, IS; Denoyer, M; Lallement, G; Pernot-Marino, I | 1 |
| Sheardown, MJ; Suzdak, PD | 1 |
| al-Zubaidy, Z; Chapman, AG; Meldrum, BS | 1 |
| Chae, LO; Edelman, NH; Melton, JE; Neubauer, JA | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z; Turski, WA; Tutka, P; Zarnowski, T | 1 |
| Anzilotti, KF; Jackson, PF; Rissolo, KC; Stauch Slusher, B | 1 |
| Dogas, Z; Hopp, FA; McCrimmon, DR; Stuth, EA; Zuperku, EJ | 1 |
| Chen, J; Graham, SH; Lan, JQ; Simon, RP | 1 |
| Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P | 1 |
| Hansen, AJ; Hillered, L; Laursen, H; Nilsson, P | 1 |
| Kimura, H; Kitamura, Y; Matsuoka, Y; Taniguchi, T; Terai, K; Tooyama, I; Tsukahara, T | 1 |
| Ballyk, B; Bleakman, R; Bufton, H; Kamboj, RK; Ornstein, PL; Schoepp, DD; Sharpe, EF; Thomas, K | 1 |
| Benz, A; Mennerick, S; Zorumski, CF | 1 |
| Brasko, J; Patrikios, P; Rai, P; Ross, DT; Sabol, MK | 1 |
| Danysz, W; Gossel, M; Löscher, W; Schmidt, WJ; Zajaczkowski, W | 1 |
| Corbett, D; Nurse, S | 1 |
| Magariños, AM; McEwen, BS | 1 |
| Bernert, H; Turski, L | 1 |
| Ishida, N; Kanai, H; Kato, N; Takazawa, A; Yamauchi, T; Yamazaki, O | 1 |
| Boireau, A; Doble, A; Meunier, M | 1 |
| Abutidze, K; Ambrosini, A; Barnard, EA; Bateson, AN; Henley, JM; Ishimaru, H; Kamboj, R; Rampersad, V; Rossier, J; Soloviev, MM; Sudan, H; Usherwood, PN | 1 |
| Ikonomidou, C; Kirby, C; Labruyere, J; Olney, JW; Qin, Y | 1 |
| Turetsky, DM; Yamada, KA | 1 |
| Teng, YD; Wrathall, JR | 1 |
| Miller, RF; Thoreson, WB | 1 |
| Balchen, T; Bruhn, T; Christensen, T; Diemer, NH; Johansen, FF; Nielsen, M; Vanicky, I | 1 |
| Carver, JM; Cortes-Burgos, L; Giordano, T; Howe, JR; Mansson, PE; Shu, J; Zhou, LM | 1 |
| Pulsinelli, W | 1 |
| Choi, EJ; Leem, JW; Paik, KS; Park, ES | 1 |
| Borsini, F; Brambilla, A; Grippa, N; Prudentino, A | 1 |
| Ohmori, J; Okada, M; Sakamoto, S; Shimizu-Sasamata, M | 1 |
| Chase, TN; Qin, ZH; Wang, Y | 1 |
| Banke, T; Krogsgaard-Larsen, P; Madsen, U; Schousboe, A; Wahl, P | 1 |
| Adreani, CM; Hill, JM; Kaufman, MP | 1 |
| Kita, H | 1 |
| Beckstead, RM | 1 |
| Holmes, GL; Liu, Z; Mikati, M; Sarkisian, M; Stafstrom, CE; Tandon, P; Werner, SJ; Yang, Y | 1 |
| Cole, BJ; Stephens, DN | 1 |
| Egorov, AV; Heinemann, U; Müller, W | 1 |
| Croucher, MJ; Patel, DR | 1 |
| Hao, JX; Xu, XJ | 1 |
| Loomis, CW; Sherman, SE | 1 |
| Hicks, C; O'Neill, MJ; Ward, M | 1 |
| Ebert, B; Krogsgaard-Larsen, P; Madsen, U; Søby, KK | 1 |
| Ferger, D; Krieglstein, J | 1 |
| Ben-Yoseph, O; Boxer, PA; Ross, BD | 1 |
| Back, T; Fritze, K; Hossmann, KA; Vogel, P; Wiessner, C; Yamashita, K | 1 |
| Malenka, RC; Nicoll, RA; Salin, PA; Scanziani, M | 1 |
| Cumberbatch, MJ; Headley, PM; Herrero, JF | 1 |
| Bonham, AC; Wilson, CG; Zhang, Z | 1 |
| Dev, KK; Henley, JM; Honoré, T; Petersen, V | 1 |
| Bouazzaoui, M; Gombos, G; Kannengieser, C; Procksch, O | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Brown, G; Jackson, A; Stephens, DN | 1 |
| Dalia, A; Wallace, LJ | 1 |
| Jensen, FE; Wang, C | 1 |
| Sheardown, MJ; Thomsen, C | 1 |
| Mendelowitz, D; Mihalevich, M; Neff, RA; Willis, A | 1 |
| Malenka, RC; Nicoll, RA; Salin, PA; Scanziani, M; Vogt, KE | 1 |
| Kawaguchi, K; Simon, RP | 3 |
| Chitravanshi, VC; Sapru, HN | 1 |
| Bruhn, T; Diemer, NH; Hu, P; Johansen, FF | 1 |
| Lo, EH; Mandeville, JB; Pierce, AR; Rosen, BR | 1 |
| Akiyama, K; Kashihara, K; Kuroda, S; Sakai, K; Shohmori, T; Tsuchida, K; Ujike, H | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Gale, K; Halonen, T; Sahibzada, N; Tortorella, A | 1 |
| Dugladze, T; Empson, RM; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Krieglstein, J; Lippert, K; Pöch, G | 1 |
| Kaila, K; Lamsa, K; Taira, T | 1 |
| Aeba, R; Ito, T; Kawada, S; Koto, A; Mitsumaru, A; Mori, A; Nakamichi, T; Odaguchi, H; Ueda, T; Yasudo, M; Yozu, R | 1 |
| Corrèges, P; Duport, S; Stoppini, L | 1 |
| Cebers, G; Hou, YN; Liljequist, S; Terenius, L | 1 |
| Busse, R; Mordvintcev, PI; Mülsch, A; Møller, A; Olesen, SP | 1 |
| Diamond, JS; Jahr, CE | 1 |
| Hughes, D; Major, MS; Parks, TN; Solum, D | 1 |
| Fusco, FR; Hirvonen, T; Hökfelt, T; Keinänen, R; Koistinaho, J; Miettinen, S; Närhi, M; Roivainen, R; Yrjänheikki, J | 1 |
| Barth, A; Malouf, AT; Newell, DW; Ricciardi, TN | 1 |
| Mares, P; Mikulecká, A; Pometlová, M | 1 |
| Heneka, MT; Klockgether, T; Kunow, M; Löschmann, PA; Schulz, JB; Wachtel, H; Wüllner, U | 1 |
| Marriott, R; Teng, YD; Wrathall, JR | 1 |
| Berman, FW; Murray, TF | 1 |
| Davies, CH; Morton, RA | 1 |
| Cui, LN; Dyball, RE; Saeb-Parsy, K | 1 |
| Dewar, D; Irving, EA; McCulloch, J; Yatsushiro, K | 1 |
| Kawasaki-Yatsugi, S; Koshiya, K; Shimizu-Sasamata, M; Yatsugi, S | 1 |
| Faussone-Pellegrini, MS; Lombardi, G; Matini, P; Moroni, F | 1 |
| Kovács, AD; Szabó, G | 1 |
| Colling, SB; Jefferys, JG; Stanford, IM; Traub, RD; Whittington, MA | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Lang, EJ; Lebel, E; Paré, D | 1 |
| Krassioukov, AV; Krenz, NR; Maiorov, DN; Weaver, LC | 1 |
| Faulkner, HJ; Jefferys, JG; Stanford, IM; Traub, RD; Whittington, MA | 1 |
| Bhat, GK; Brann, DW; Mahesh, VB; Ping, L | 1 |
| Kaila, K; Lamsa, K | 1 |
| Livingston, FS; Mooney, R | 1 |
| Cook, JC; Gregg, AE; Sanders, BJ; Soltis, RP | 1 |
| Davis, M; Walker, DL | 2 |
| Richardson, CM; Wakerley, JB | 1 |
| Lu, Y; Wehner, JM | 1 |
| Ikonomidou, C; Turski, L | 1 |
| Arias, C; Arrieta, I; Massieu, L; Tapia, R | 1 |
| Członkowska, A; Płaźnik, A; Siemiatkowski, M | 1 |
| Cossu, M; Fedele, E; Fontana, G; Munari, C; Raiteri, M | 1 |
| Chittajallu, R; Dev, KK; Henley, JM | 1 |
| Canzoniero, LM; Choi, DW; Grabb, M; Monyer, H; Sensi, SL; Sheline, CT; Weishaupt, JH; Ying, HS | 1 |
| Canzoniero, LM; Choi, DW; Kerchner, GA; Koh, JY; Sensi, SL; Ying, HS; Yu, SP | 1 |
| Ciani, E; Contestabile, A; Dall'Olio, R; Gandolfi, O; Sparapani, M | 1 |
| Behr, J; Empson, RM; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Calcutt, NA; Chaplan, SR | 1 |
| Conti, A; Fedele, E; Raiteri, M | 1 |
| Fedele, E; Raiteri, M; Varnier, G | 1 |
| Li, Y; Vartanian, AJ; White, FJ; Wolf, ME; Xue, CJ | 1 |
| Bickler, PE; Bornheim, LM; Gray, AT; Hampson, AJ; Hansen, BM; Leonoudakis, DJ; Scanziani, M; Yost, CS | 1 |
| Iadecola, C; Yang, G | 1 |
| Dreshaj, IA; Erokwu, B; Haxhiu, MA | 1 |
| Beitz, AJ; Clark, HB; Feddersen, RM; Iadecola, C; Yang, G; Zhang, F | 1 |
| Meredith, MA; Ramoa, AS | 1 |
| Ohno-Shosaku, T; Sawada, S; Yamamoto, C | 1 |
| Follesa, P; Mocchetti, I; Wrathall, JR | 1 |
| Brennan, TJ; Umali, E; Zahn, PK | 1 |
| Bianchi, L; Della Corte, L; Giovannini, MG; Pepeu, G; Rakovska, A | 1 |
| Daggett, LP; Deal, C; Hess, SD; Jachec, C; Johnson, EC; Lin, F; Rao, SP; Varney, MA; Veliçelebi, G | 1 |
| Hokamura, K; Kawano, K; Kawazura, H; Nakashima, M; Shimazu, Y; Umemura, K | 1 |
| Vanover, KE | 1 |
| Blaszczak, P; Turski, WA | 1 |
| Covey, DF; He, YY; Hsu, CY; Hu, R; Hu, Y; Yamada, KA | 1 |
| Baubichon, D; Filliat, P; Lallement, G; Pernot-Marino, I | 1 |
| Kuo, MF; Murphy, S; Papadopoulos, MD; Pastuszko, A; Song, D; Wilson, DF | 1 |
| Newman, EA; Zahs, KR | 1 |
| Braisted, JC; Chavko, M; Harabin, AL; Outsa, NJ | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Reggiani, A; Tomasini, MC; Trist, DG | 1 |
| Hole, K; Svendsen, F; Tjølsen, A | 1 |
| Rosenmund, C; Stern-Bach, Y; Stevens, CF | 1 |
| Bonnot, A; Bouc, AM; Corio, M; Viala, D | 1 |
| Bartfai, T; Caltavuturo, C; Consolo, S; Uboldi, MC | 1 |
| Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G | 1 |
| Borday, V; Denavit-Saubié, M; Foutz, AS; Nordholm, L | 1 |
| Dretchen, KL; Gillis, RA; Hernandez, YM; McManigle, JE; Taveira Da Silva, AM | 1 |
| Karpuk, N; Luhmann, HJ; Qü, M; Zilles, K | 1 |
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| Folbergrová, J; Haugvicová, R; Kubová, H; Mareš, P | 1 |
| Callison, JJ; Cook-Snyder, DR; McCarthy, N; Miller, JR; Navarrete-Opazo, AA; Palkovic, B; Stucke, AG; Stuth, EAE; Zuperku, EJ | 1 |
| Fu, W; Huang, P; Jiang, L; Liu, J; Luo, L; Tang, X; Xu, N; Yi, W; Zhang, H; Zhou, J | 1 |
| Fujita, Y; Hashimoto, K; Iwata, M; Muneoka, K; Oda, Y; Shirayama, Y | 1 |
| Bauer, MR; Boehm, SL; Garcy, DP | 1 |
| Bancroft, EA; Srinivasan, R | 1 |
| Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Miyahara, Y; Nishimori, T | 1 |
| Balu, DT; Coyle, JT; Takagi, S | 1 |
| Doura, T; Hamachi, I; Kiyonaka, S; Komatsu, K; Ojima, K; Shiraiwa, K; Soga, K; Takato, M; Yuzaki, M | 1 |
| Amchova, P; Ruda-Kucerova, J; Siska, F; Tizabi, Y | 1 |
| Kim, MH; Kim, YS; Oh, SP; Song, WS; Yoon, SH | 1 |
| Bauer, MR; Boehm, SL; Germano, DM; McVey, MM; Zhang, Y | 1 |
| Chang, ZS; Liang, K; Man, XY; Mo, YX; Wang, L; Xiao, ZY | 1 |
7 review(s) available for quinoxalines and 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
| Article | Year |
|---|---|
The pharmacology of AMPA receptors and their antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Quinoxalines; Receptors, AMPA | 1993 |
The importance of glutamate receptors in brain ischemia.
Topics: Animals; Brain Ischemia; Calcium; Ischemic Attack, Transient; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Time Factors | 1995 |
Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haplorhini; Humans; Mice; MPTP Poisoning; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Quinoxalines; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus.
Topics: Age Factors; Animals; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Electrophysiology; Epilepsy, Temporal Lobe; Hippocampus; Hypoxia; In Vitro Techniques; Lorazepam; Quinoxalines; Rats | 1996 |
Competitive AMPA receptor antagonists.
Topics: Animals; Binding, Competitive; Drug Design; Humans; Neuroprotective Agents; Quinoxalines; Receptors, AMPA | 2007 |
[AMPA receptor].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amyotrophic Lateral Sclerosis; Animals; Drug Design; Humans; Quinoxalines; Receptors, AMPA | 2008 |
The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Line; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Models, Molecular; Protein Conformation; Protein Subunits; Quinoxalines; Receptors, AMPA | 2010 |
1158 other study(ies) available for quinoxalines and 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
| Article | Year |
|---|---|
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter; Recombinant Proteins; Xenopus laevis | 1992 |
NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy-piperazin-propyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Apomorphine; Dopamine Agents; Drug Synergism; Ibotenic Acid; Lisuride; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1992 |
Administration of quinolinic acid in the rat hippocampus induces expression of c-fos and NGFI-A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Hippocampus; Ibotenic Acid; In Situ Hybridization; Injections, Intraperitoneal; Male; Oligonucleotide Probes; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cell Membrane Permeability; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Cortex; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury.
Topics: Animals; Contusions; Female; Hindlimb; Motor Activity; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord Injuries | 1992 |
Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cell Count; Hippocampus; Male; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Methohexitone antagonises kainate and epileptiform activity in rat neocortical slices.
Topics: Action Potentials; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Methohexital; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Kainic Acid | 1992 |
The non-NMDA glutamate antagonist NBQX blocks the local hippocampal toxicity of kainic acid, but not the diffuse extrahippocampal damage.
Topics: Animals; Hippocampus; Injections; Injections, Intraperitoneal; Kainic Acid; Limbic System; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid | 1992 |
AMPA receptor competitive antagonism reduces halothane MAC in rats.
Topics: Anesthesia, Inhalation; Animals; Excitatory Amino Acid Antagonists; Halothane; Infusions, Intravenous; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1992 |
The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates.
Topics: Acoustic Stimulation; Amygdala; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebral Cortex; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kindling, Neurologic; Mice; Mice, Inbred DBA; Neural Pathways; Papio; Photic Stimulation; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Reflex; Synaptic Transmission | 1992 |
Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Glucose; Blood Pressure; Body Temperature; Cell Death; Dizocilpine Maleate; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Inhibition of cisplatin-induced emesis in ferrets by the non-NMDA receptor antagonists NBQX and CNQX.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Exploratory Behavior; Ferrets; Imidazoles; Male; Ondansetron; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Serotonin Antagonists; Vomiting | 1992 |
The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cell Death; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamic Acid; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
MK-801 selectively protects mouse arcuate neurons in vivo against glutamate toxicity.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Neurons; Quinoxalines | 1992 |
NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Brain Edema; Glutamates; Glutamic Acid; Hematocrit; Male; Oxadiazoles; Protamines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Serum Albumin | 1992 |
AMPA and NMDA receptor antagonists do not decrease hippocampal glutamate concentrations during transient global ischemia.
Topics: Animals; Aspartic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reperfusion | 1992 |
Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Mice; Potassium; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1992 |
Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Cell Death; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Insulin Coma; Male; Necrosis; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1992 |
Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Electromyography; Ibotenic Acid; Kindling, Neurologic; Locomotion; Male; Mice; Muscle Spasticity; Quinoxalines; Rats; Rats, Inbred Strains; Reflex; Spinal Cord | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Pharmacological characterization of non-NMDA subtypes of glutamate receptor in the neonatal rat hemisected spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Methohexital; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitution.
Topics: Animals; Electrophysiology; Evoked Potentials; Hippocampus; In Vitro Techniques; Ion Channels; Neurons; Nitro Compounds; Oocytes; Pyramidal Tracts; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA, Messenger; Synapses; Xenopus | 1992 |
Regional cerebral protein synthesis after transient ischemia in the rat: effect of the AMPA antagonist NBQX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic Acid; Ischemic Attack, Transient; Male; Methionine; Nerve Tissue Proteins; Neurons; Organ Specificity; Quinoxalines; Rats; Rats, Wistar; Sulfur Radioisotopes | 1992 |
The AMPA antagonist, NBQX, protects against ischemia-induced loss of cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Ibotenic Acid; Ischemic Attack, Transient; Male; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar | 1992 |
Actions of a metabotropic glutamate receptor agonist in immature and adult rat cerebellum.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebellum; Cycloleucine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Purkinje Cells; Quinoxalines; Rats; Receptors, Glutamate | 1992 |
Synergism of NBQX with dopamine agonists in the 6-OHDA rat model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Drug Synergism; Lisuride; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Rats; Rats, Wistar; Stereotaxic Techniques; Substantia Nigra | 1992 |
Probenecid pretreatment enhances anticonvulsant action of NBQX in mice.
Topics: Animals; Anticonvulsants; Ataxia; Drug Synergism; Injections, Intravenous; Male; Mice; Motor Activity; Probenecid; Quinoxalines; Seizures | 1992 |
The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model.
Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Infusions, Intravenous; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Ketamine decreases plasma catecholamines and improves outcome from incomplete cerebral ischemia in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Epinephrine; Fentanyl; Ketamine; Male; N-Methylaspartate; Norepinephrine; Oxygen Consumption; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Delayed AMPA receptor blockade reduces cerebral infarction induced by focal ischemia.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Infarction; Cerebrovascular Circulation; Ischemic Attack, Transient; Male; Oxadiazoles; Oxygen; Partial Pressure; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diazepam; Dizocilpine Maleate; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kinetics; Male; Nerve Growth Factors; Nerve Tissue Proteins; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; RNA, Messenger; Tetrodotoxin | 1991 |
The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys.
Topics: Animals; Dopamine; Female; Globus Pallidus; Levodopa; Macaca mulatta; MPTP Poisoning; Parkinson Disease, Secondary; Quinoxalines; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Transmission | 1991 |
Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats.
Topics: Animals; Cell Death; Chlorides; Hippocampus; Ischemic Attack, Transient; Lithium; Lithium Chloride; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Reperfusion; Sodium Chloride | 1991 |
Inhibition by glutamate antagonists, MK-801 and NBQX, of cutaneo-cardiovascular pain reflex in rats.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dizocilpine Maleate; Female; Heart Rate; Pain; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Reflex; Skin; Skin Physiological Phenomena | 1991 |
Protection against post-ischemic behavioral pathology by the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil.
Topics: Animals; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Motor Activity; Neurons; Pyramidal Tracts; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus.
Topics: Action Potentials; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Strychnine; Synapses; Tetrodotoxin; Vagus Nerve | 1991 |
The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Tonic-Clonic; Female; Male; Papio; Photic Stimulation; Quinoxalines; Rats; Rats, Inbred Strains; Reflex | 1991 |
Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Gene Expression; Hippocampus; Insulin Coma; Ischemic Attack, Transient; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Nucleic Acid Hybridization; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors | 1992 |
Cardiac uptake kinetics and possible dynamic effects of a new cerebral antiischaemic compound FG 9202 (NBQX) studied in the isolated rabbit heart.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Perfusion; Quinoxalines; Rabbits | 1991 |
Determination of the neuroprotective agent 6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione in plasma using high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Nervous System; Quinoxalines; Rats; Rats, Inbred Strains; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1991 |
The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Female; Ibotenic Acid; Male; Mice; Mice, Inbred DBA; Postural Balance; Quinoxalines; Seizures | 1991 |
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Female; Glutamate Decarboxylase; Kynurenic Acid; Male; Microinjections; Microscopy, Electron; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Epilepsy; Kindling, Neurologic; Male; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1991 |
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Callithrix; Disease Models, Animal; Drug Synergism; Ibotenic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1991 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
Electrophysiology and morphology of a new type of cell within layer II of the rat lateral entorhinal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Axons; Cell Physiological Phenomena; Electrophysiology; Entorhinal Cortex; Female; Membrane Potentials; Quinoxalines; Rats; Rats, Wistar | 1995 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Pharmacological modification of glutamate neurotoxicity in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzofurans; Blood Pressure; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Male; Microdialysis; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrimidines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar | 1993 |
Differential effects of NBQX on the distal and local toxicity of glutamate agonists administered intra-hippocampally.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Diazepam; Hippocampus; Injections; Kainic Acid; Limbic System; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate | 1993 |
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Male; N-Methylaspartate; Pilot Projects; Quinoxalines; Rats; Rats, Inbred SHR; Sodium Chloride | 1994 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Persistent AMPA receptor stimulation alters [Ca2+]i homeostasis in cultures of embryonic dopaminergic neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dopamine; Homeostasis; Mesencephalon; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
Non-NMDA receptor-mediated regulation of hypothalamic dopaminergic neurons in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dopamine; Female; Hypothalamus; Kainic Acid; Male; Median Eminence; Neostriatum; Neurons; Paraventricular Hypothalamic Nucleus; Prolactin; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, AMPA; Substantia Nigra | 1994 |
Importance of nitric oxide for local increases of blood flow in rat cerebellar cortex during electrical stimulation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Amino Acid Oxidoreductases; Amino Acids; Animals; Anticonvulsants; Arginine; Carbon Dioxide; Cerebellar Cortex; Cerebrovascular Circulation; Drug Interactions; Electric Stimulation; Isomerism; Magnesium; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Tetrodotoxin | 1994 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 1994 |
AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Iontophoresis; Male; N-Methylaspartate; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Synaptic Transmission | 1994 |
A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Hot Temperature; Injections, Intravenous; Iontophoresis; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord | 1994 |
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Superior Colliculi | 1994 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; Cell Death; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Isoquinolines; Male; Malonates; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission | 1994 |
NBQX suppresses inhibitory glycine currents in retinal ganglion cells.
Topics: Ambystoma; Animals; Glycine; In Vitro Techniques; Ion Channels; Membrane Potentials; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Retinal Ganglion Cells; Tetrodotoxin | 1994 |
Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX.
Topics: Animals; Body Temperature; Brain Chemistry; Dizocilpine Maleate; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin | 1995 |
Synergy between diazepam and NBQX in preventing neuronal death caused by non-NMDA agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Diazepam; Drug Synergism; Kainic Acid; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 1994 |
NBQX prevents contralateral but not ipsilateral seizure-induced cytotoxicity of kainate but not AMPA-reversal at high doses of NBQX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures | 1994 |
Regional variations in the pharmacology of AMPA receptors as revealed by receptor autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Cerebellar Cortex; Glutamic Acid; Indoles; Male; Molecular Structure; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides | 1994 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
The importance of two specific domains in ligand binding to the AMPA/kainate glutamate receptors GluR2 and GluR6.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Blotting, Western; Calcium; Cell Line; Cricetinae; Gene Expression; Kainic Acid; Kidney; Quinoxalines; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Transfection; Tritium | 1995 |
Differential regulation by N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors of acetylcholine release from the rat striatum in vivo.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Male; Microdialysis; Neostriatum; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburide; Heart Arrest; Hypoxia; Ion Channels; Male; Nimodipine; Piperidines; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Sodium; Thiazoles | 1995 |
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins | 1995 |
Characterization of the binding of [3H]NS 257, a novel competitive AMPA receptor antagonist, to rat brain membranes and brain sections.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Cell Membrane; Cerebral Cortex; Hydrogen-Ion Concentration; Indoles; Kainic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sulfonamides; Thiocyanates; Tritium | 1995 |
AMPA-, but not NMDA-, receptor blocker, NBQX, prevents seizure induction in magnesium-deficient rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Magnesium Deficiency; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Short-latency excitation of phrenic motor output mediated by non-NMDA receptors.
Topics: Animals; Cats; Evoked Potentials; Excitatory Amino Acid Antagonists; Laryngeal Nerves; Motor Neurons; Phrenic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synaptic Transmission | 1995 |
The AMPA antagonist NBQX protects thalamic reticular neurons from degeneration following cardiac arrest in rats.
Topics: Animals; Excitatory Amino Acid Antagonists; Heart Arrest; Male; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, AMPA; Reticular Formation; Thalamus | 1995 |
NBQX, a selective antagonist of the AMPA receptor, affects neither field potentials nor long-term potentiation in vivo.
Topics: Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Long-Term Potentiation; Male; Membrane Potentials; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1995 |
NBQX blocks acute and late epileptogenic effects of perinatal hypoxia.
Topics: Age Factors; Animals; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Flurothyl; Hypoxia, Brain; Lorazepam; Male; Quinoxalines; Rats; Receptors, AMPA | 1995 |
Evidence for an anxiogenic action of AMPA receptor antagonists in the plus-maze test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Quinoxalines; Receptors, AMPA | 1995 |
Anticonvulsant, anxiolytic and discriminative effects of the AMPA antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX).
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Excitatory Amino Acid Antagonists; Female; Male; Mice; Mice, Inbred DBA; Morphine; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures | 1995 |
Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardiine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Male; Pyrimidinones; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Synaptic Membranes; Tritium; Uracil | 1995 |
AMPA receptor antagonism attenuates MK-801-induced hypermetabolism in the posterior cingulate cortex.
Topics: Animals; Autoradiography; Behavior, Animal; Deoxyglucose; Dizocilpine Maleate; Gyrus Cinguli; Limbic System; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stereotyped Behavior; Tissue Distribution | 1995 |
Kainate/AMPA receptor antagonists are anticonvulsant against the tonic hindlimb component of pentylenetetrazol-induced seizures in developing rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Anticonvulsants; Behavior, Animal; Epilepsy, Tonic-Clonic; Hindlimb; Male; Muscle Tonus; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Synaptic Transmission | 1995 |
Blockers of NMDA-operated channels decrease glutamate and aspartate extracellular accumulation in striatum during forebrain ischaemia in rats.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Corpus Striatum; Dizocilpine Maleate; Glutamic Acid; Magnesium; Male; Microdialysis; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
NMDA and non-NMDA receptors on rat supraoptic nucleus neurons activated monosynaptically by olfactory afferents.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Female; Kynurenic Acid; Male; Neurons; Neurons, Afferent; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Synapses | 1995 |
Novel synaptic potentials in cerebellar Purkinje cells: probable mediation by metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Baclofen; Bicuculline; Calcium; Cerebellum; Electric Stimulation; In Vitro Techniques; Interneurons; Ion Channels; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
NBQX inhibits AMPA-induced locomotion after injection into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Injections; Kainic Acid; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 1993 |
The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine Agents; Excitatory Amino Acid Antagonists; Ibotenic Acid; Indoles; Macaca fascicularis; Motor Activity; Oxazines; Parkinson Disease; Phenanthridines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate | 1993 |
Blockade of AMPA receptors reduces brain edema following opening of the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Dizocilpine Maleate; Evans Blue; Excitatory Amino Acid Antagonists; Injections, Intravenous; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Specific Gravity; Staining and Labeling | 1993 |
Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo(F)-quinoxaline (NBQX).
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Pertussis Toxin; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Virulence Factors, Bordetella | 1993 |
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gerbillinae; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kinetics; Male; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
The effect of an AMPA antagonist (NBQX) on postischemic neuron loss and protein synthesis in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Autoradiography; Brain; Frontal Lobe; Hippocampus; Ischemic Attack, Transient; Male; Methionine; Nerve Tissue Proteins; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Wistar; Sulfur Radioisotopes; Thalamus | 1993 |
Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Diseases; Dizocilpine Maleate; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Prosencephalon; Quinoxalines; Rats; Rats, Wistar | 1993 |
Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced responses in Xenopus oocytes expressing chick brain glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Chick Embryo; Electrophysiology; Glutamine; Kainic Acid; Kinetics; Oocytes; Quinoxalines; Receptors, Glutamate; RNA, Messenger; Xenopus | 1993 |
Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Kainic Acid; Male; Mice; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 1993 |
2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline enhances the protective activity of common antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Ataxia; Avoidance Learning; Behavior, Animal; Drug Synergism; Electroshock; Male; Memory; Mice; Motor Activity; Psychomotor Performance; Quinoxalines; Seizures | 1993 |
Effects of bromohomoibotenate on metabotropic glutamate receptors.
Topics: Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Cricetinae; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kidney; Membranes; Phosphatidylinositols; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
An in vivo pharmacological study of single group Ia fibre contacts with motoneurones in the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Dendrites; Electrophysiology; Motor Neurons; Neural Pathways; Quinoxalines; Spinal Cord; Synapses; Time Factors | 1994 |
Passive and synaptic properties of hippocampal neurons grown in microcultures and in mass cultures.
Topics: Animals; Cells, Cultured; Evoked Potentials; Hippocampus; Microscopy, Electron; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 1995 |
Fenbufen pretreatment potentiates the anticonvulsant activity of CPPene and NBQX in DBA/2 mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Synergism; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Motor Activity; Phenylbutyrates; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study.
Topics: Animals; Cell Death; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar | 1995 |
Presynaptic influence on the time course of fast excitatory synaptic currents in cultured hippocampal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Magnesium; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1995 |
Potentiated necrosis of cultured cortical neurons by neurotrophins.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Mice; N-Methylaspartate; Necrosis; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotrophin 3; Quinoxalines; Receptors, AMPA | 1995 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Simultaneous blockade of non-NMDA ionotropic receptors and NMDA receptor-associated ionophore partially protects hippocampal slices from protein synthesis impairment due to simulated ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; In Vitro Techniques; Ionophores; Leucine; Male; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Immunohistochemistry; Injections; Male; Neostriatum; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1995 |
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis.
Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury | 1994 |
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.
Topics: Alprazolam; Animals; Avoidance Learning; Benzothiadiazines; Brain; Chlorothiazide; Cognition; Diazoxide; Electrophysiology; Glutamates; Ligands; Male; Maze Learning; Phosphatidylinositols; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Stereoisomerism; Synaptosomes | 1995 |
Characteristics and localization of high-affinity kainate sites in slide-mounted sections of rat cerebellum.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebellum; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Kinetics; Male; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tritium | 1994 |
Neurochemical evidence that AMPA receptor-mediated tonic inhibition of hypothalamic dopaminergic neurons occurs via activation of inhibitory interneurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypothalamus; Interneurons; Male; Median Eminence; Neurons; Pituitary Gland; Quinoxalines; Rats; Receptors, AMPA; Receptors, Opioid, kappa | 1994 |
Endogenous excitatory amino acids tonically stimulate striatal acetylcholine release through NMDA but not AMPA receptors.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Electrochemistry; Excitatory Amino Acids; Extracellular Space; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Male; Microinjections; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; RNA, Messenger | 1994 |
Comparison of the effects of NMDA and AMPA antagonists on the locomotor activity induced by selective D1 and D2 dopamine agonists in reserpine-treated mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenethylamines; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine | 1994 |
Hypoxia-ischemia in the neonatal rat brain: histopathology after post-treatment with NMDA and non-NMDA receptor antagonists.
Topics: Animals; Animals, Newborn; Brain Damage, Chronic; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Hypoxia, Brain; Injections, Intraperitoneal; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Severity of Illness Index; Treatment Outcome | 1994 |
NMDA and not non-NMDA receptor antagonists are protective against seizures induced by homocysteine in neonatal rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Dizocilpine Maleate; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Hepatic uptake and biliary excretion of the neuroprotectant 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo-(F)-quinoxaline in rat liver. Involvement of an organic anion transport system.
Topics: Animals; Bile; Biological Transport; Dose-Response Relationship, Drug; Liver; Male; Perfusion; Probenecid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1995 |
Modulation of soman-induced neuropathology with an anticonvulsant regimen.
Topics: Animals; Anticonvulsants; Atropine; Hippocampus; Male; Olfactory Pathways; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Soman | 1994 |
NBQX reduces threshold of protein synthesis inhibition in focal ischaemia in rats.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Differential Threshold; Male; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA | 1994 |
AMPA glutamate receptor antagonism reduces neurologic injury after hypothermic circulatory arrest.
Topics: Animals; Autoradiography; Brain Diseases; Cardiopulmonary Bypass; Dogs; Electroencephalography; Heart Arrest, Induced; Hypothermia, Induced; Male; Necrosis; Neurons; Postoperative Care; Quinoxalines; Receptors, AMPA; Reperfusion Injury; Rewarming; Survival Rate; Time Factors | 1995 |
Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Flumazenil; Male; Mice; Muscle Relaxants, Central; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Reflex; Seizures; Synaptic Transmission | 1994 |
Effects of memantine on synaptic transmission in the hippocampus in vitro.
Topics: Animals; Electric Stimulation; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Male; Memantine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serine; Synapses; Synaptic Transmission; Theta Rhythm | 1995 |
Billion-fold difference in the toxic potencies of two excitatory plant amino acids, L-BOAA and L-BMAA: biochemical and morphological studies using mouse brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Diamino; Animals; beta-Alanine; Brain; Brain Chemistry; Cyanobacteria Toxins; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Histocytochemistry; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Neurotoxins; Paraffin Embedding; Plants; Potassium; Quinoxalines | 1993 |
Blockade of the locomotor stimulant effects of cocaine and methamphetamine by glutamate antagonists.
Topics: Amino Acids; Animals; Cocaine; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Methamphetamine; Mice; Motor Activity; Pyrrolidinones; Quinoxalines | 1993 |
Cysteine sulphinate and cysteate: mediators of cysteine toxicity in the neonatal rat brain?
Topics: Amino Acids; Animals; Animals, Newborn; Brain; Cerebral Cortex; Cysteic Acid; Cysteine; Dizocilpine Maleate; Female; Male; Nerve Degeneration; Neurons; Neurotoxins; Neurotransmitter Agents; Organ Specificity; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epilepsies, Partial; Female; Kindling, Neurologic; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1993 |
Neuroprotection with NBQX and thrombolysis with rt-PA in rat embolic stroke.
Topics: Animals; Brain Edema; Cerebral Infarction; Cerebrovascular Circulation; Fibrinolysis; Intracranial Embolism and Thrombosis; Male; Paralysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Thrombolytic Therapy; Tissue Plasminogen Activator; Weight Loss | 1993 |
Maintenance of pharmacologically-immature glutamate receptors by aberrant synapses in the chick cochlear nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chick Embryo; Chickens; Cochlear Nucleus; Quinoxalines; Receptors, Glutamate; Synapses | 1993 |
Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cerebral Cortex; Dizocilpine Maleate; Energy Metabolism; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; Kynurenic Acid; Neurotoxins; Phosphocreatine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Drug Interactions; Ergolines; Haloperidol; Levodopa; Male; Pilot Projects; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
Influence of hypoxia on excitation and GABAergic inhibition in mature and developing rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Cell Hypoxia; Electric Conductivity; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synaptic Transmission | 1993 |
Over-additive protective effect of dizocilpine and NBQX against neuronal damage.
Topics: Animals; Brain Ischemia; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Mice; Neurons; Quinoxalines; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, AMPA | 1994 |
Nucleus tractus solitarius and excitatory amino acids in afferent-evoked inspiratory termination.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Blood Pressure; Cats; Decerebrate State; Electric Stimulation; Female; Intercostal Nerves; Laryngeal Nerves; Male; Neurons, Afferent; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 1994 |
NMDA receptors are involved in temporal integration in the oculomotor system of the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Darkness; Eye Movements; Oculomotor Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1994 |
NBQX, a competitive non-NMDA receptor antagonist, reduces degeneration due to focal spinal cord ischemia.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ischemia; Lasers; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; Spinal Cord; Time Factors | 1994 |
Kainate injury to cultured basal forebrain cholinergic neurons is Ca2+ dependent.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Choline O-Acetyltransferase; Cobalt; Dizocilpine Maleate; Fetus; Immunohistochemistry; Kainic Acid; Kinetics; Mice; Neurons; Neurotoxins; Prosencephalon; Quinoxalines; Receptors, AMPA; Time Factors | 1994 |
MK-801 and NBQX prevent electrically induced status epilepticus.
Topics: Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Electric Stimulation; Hippocampus; Injections, Intraperitoneal; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine; Status Epilepticus | 1994 |
Regulation of BDNF promoters in the rat hippocampus.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Exons; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Ribonucleases; RNA, Messenger | 1994 |
Over-additive anticonvulsant effect of memantine and NBQX in kindled rats.
Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Drug Synergism; Female; Kindling, Neurologic; Memantine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 1994 |
Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX.
Topics: Animals; Dose-Response Relationship, Drug; Female; Kainic Acid; Osmolar Concentration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries | 1994 |
Involvement of the N-methyl-D-aspartate receptors of the vestibular nucleus in the gaze-holding system of the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Eye Movements; Microinjections; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Vestibular Nuclei | 1994 |
Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat.
Topics: Analgesics; Animals; Formaldehyde; Inflammation; Male; N-Methylaspartate; Nociceptors; Pain Measurement; Pipecolic Acids; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
Pharmacological reduction of brain edema induced by intracarotid infusion of protamine sulphate: a comparison between a free radical scavenger and an AMPA receptor antagonist.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Cortex; Infusions, Intra-Arterial; Lipid Peroxides; Male; Phenothiazines; Pregnatrienes; Premedication; Protamines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serum Albumin; Specific Gravity | 1994 |
Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate.
Topics: Animals; Brain Edema; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Energy Metabolism; Glutamic Acid; Kynurenic Acid; Magnetic Resonance Spectroscopy; Organ Size; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Sodium Channels | 1994 |
Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Dizocilpine Maleate; Estradiol; Female; Hippocampus; Ovariectomy; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1994 |
Antiepileptic effects of NBQX against soman-induced seizures.
Topics: Animals; Anticonvulsants; Atropine; Drug Therapy, Combination; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Muscarinic; Soman | 1994 |
Combined blockade of NMDA and non-NMDA receptors produces respiratory arrest in the adult cat.
Topics: Animals; Cats; Dizocilpine Maleate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Respiration Disorders | 1994 |
Excitatory amino acid receptor antagonists modify regional cerebral metabolic responses to levodopa in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Organ Specificity; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
NMDA and non-NMDA receptors may play distinct roles in timing mechanisms and transmission in the feline respiratory network.
Topics: Action Potentials; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Carbon Dioxide; Cats; Dizocilpine Maleate; N-Methylaspartate; Neurons; Phrenic Nerve; Pulmonary Alveoli; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Synaptic Transmission; Time Factors | 1994 |
AMPA receptor antagonists and local cerebral glucose utilization in the rat.
Topics: Animals; Autoradiography; Brain; Dose-Response Relationship, Drug; Glucose; Isoquinolines; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles | 1994 |
Selective protection of neuropeptide containing dentate hilar interneurons by non-NMDA receptor blockade in an animal model of status epilepticus.
Topics: Animals; Cell Survival; Hippocampus; Interneurons; Male; Neuropeptides; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Status Epilepticus | 1994 |
Prevention of periinfarct direct current shifts with glutamate antagonist NBQX following occlusion of the middle cerebral artery in the rat.
Topics: Animals; Brain; Cerebral Arteries; Cerebral Infarction; Electroencephalography; Electrophysiology; Male; Quinoxalines; Rats; Receptors, AMPA | 1994 |
Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebrovascular Disorders; Dizocilpine Maleate; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression; Genes, fos; Genes, jun; Immediate-Early Proteins; In Situ Hybridization; Kinetics; Male; Membrane Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Photochemistry; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Ciliary Neurotrophic Factor; RNA, Messenger; Rose Bengal; Time Factors; Transcription Factors | 1993 |
Coadministration of atropine, NBQX and TCP against soman-induced seizures.
Topics: Animals; Atropine; Drug Synergism; Electroencephalography; Male; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Soman | 1994 |
A comparison of the actions of agonists and antagonists at non-NMDA receptors of C fibres and motoneurones of the immature rat spinal cord in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Concanavalin A; In Vitro Techniques; Kainic Acid; Motor Neurons; Nerve Fibers; Quinoxalines; Rats; Receptors, Amino Acid; Spinal Cord | 1993 |
Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Female; Lamotrigine; Male; Motor Activity; Phenytoin; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Triazines | 1993 |
Motor performance, histologic damage, and calcium influx in rats treated with NBQX after focal ischemia.
Topics: Animals; Brain; Brain Ischemia; Calcium; Calmodulin; Injections, Intraperitoneal; Injections, Intravenous; Male; Motor Activity; Quinoxalines; Rats; Rats, Inbred SHR | 1994 |
NMDA and non-NMDA receptor gene expression following global brain ischemia in rats: effect of NMDA and non-NMDA receptor antagonists.
Topics: Animals; Autoradiography; Brain; Brain Ischemia; Gene Expression; In Situ Hybridization; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reperfusion | 1994 |
Kainic acid-induced seizures and brain damage in the rat: different effects of NMDA- and AMPA receptor antagonists.
Topics: Animals; Behavior, Animal; Brain; Dizocilpine Maleate; Drug Synergism; Kainic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Rate | 1993 |
6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: structure-activity relationships for the AMPA-type non-NMDA receptor.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Binding Sites; Brain; Imidazoles; Male; Mice; Mice, Inbred DBA; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship | 1994 |
Hippocampal damage produced in rats by alpha-dendrotoxin--a selective K+ channel blocker--involves non-NMDA receptor activation.
Topics: Animals; Elapid Venoms; Electroencephalography; Hippocampus; Male; Nerve Degeneration; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Seizures | 1994 |
Potentiation of MK-801-induced breathing impairment by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: Animals; Blood Pressure; Cats; Dizocilpine Maleate; Female; Heart Rate; Injections, Intravenous; Male; Phrenic Nerve; Quinoxalines; Receptors, AMPA; Respiration; Respiratory Function Tests | 1994 |
Intravenous NBQX inhibits spontaneously occurring sympathetic nerve activity and reduces blood pressure in cats.
Topics: Animals; Autonomic Denervation; Blood Pressure; Cats; Depression, Chemical; Electrophysiology; Female; Heart Rate; Infusions, Intravenous; Male; Pressoreceptors; Quinoxalines; Receptors, AMPA; Sympathetic Nervous System; Sympatholytics | 1994 |
NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline) did not affect recovery of high energy phosphates and pH in early reperfusion in a rat model of transient forebrain ischemia. Or: an in vivo 31P NMR spectroscopy study.
Topics: Acidosis; Adenosine Triphosphate; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorus; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion; Time Factors | 1994 |
The effect of the non-NMDA receptor antagonist GYKI 52466 and NBQX and the competitive NMDA receptor antagonist D-CPPene on the development of amygdala kindling and on amygdala-kindled seizures.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Electric Stimulation; Kindling, Neurologic; Male; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Hippocampus; Kindling, Neurologic; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors | 1994 |
A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding.
Topics: Animals; Binding, Competitive; Calcium; Calcium Chloride; Cerebral Cortex; Excitatory Amino Acid Antagonists; Indoles; Kainic Acid; Male; Membranes; Molecular Structure; Neuromuscular Depolarizing Agents; Oximes; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Tritium | 1993 |
Systemic excitatory amino acid receptor antagonists of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and of the N-methyl-D-aspartate (NMDA) receptor relieve mechanical hypersensitivity after transient spinal cord ischemia in
Topics: Animals; Dizocilpine Maleate; Female; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Skin Physiological Phenomena; Spinal Cord; Vocalization, Animal | 1993 |
Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord.
Topics: Animals; Capsaicin; Female; GABA Antagonists; Long-Term Potentiation; Male; N-Methylaspartate; Neurons, Afferent; Quinoxalines; Rats; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
Interaction of the competitive AMPA receptor antagonist NBQX with hexobarbital.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Drug Interactions; Female; Hexobarbital; Infusions, Intravenous; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sleep; Time Factors | 1993 |
Effects of MK-801 and NBQX on acute recovery of piglet cerebral metabolism after hypothermic circulatory arrest.
Topics: Animals; Brain; Cerebrovascular Circulation; Dizocilpine Maleate; Energy Metabolism; Glucose; Heart Arrest, Induced; Hydrogen-Ion Concentration; Intracellular Membranes; Lactates; Lactic Acid; Oxygen; Phosphates; Quinoxalines; Swine; Swine, Miniature | 1994 |
Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.
Topics: Amyloid beta-Peptides; Animals; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Mice; Neurons; Neurotoxins; Nimodipine; Quinoxalines | 1994 |
Enhancing the efficacy of thrombolysis by AMPA receptor blockade with NBQX in a rat embolic stroke model.
Topics: Animals; Blood Pressure; Cerebral Angiography; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Fibrinolytic Agents; Intracranial Embolism and Thrombosis; Male; Plasminogen Activators; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1993 |
Non-NMDA glutamate receptors are involved in the maintenance of status epilepticus.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cerebral Ventricles; Dizocilpine Maleate; Electric Stimulation; Electroencephalography; Hippocampus; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Muscarinic; Scopolamine; Status Epilepticus | 1993 |
Diazepam dependence prevented by glutamate antagonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Tolerance; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Muscle Tonus; Piperazines; Quinoxalines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1993 |
Impairment of Fos protein formation in the rat infarct borderzone by MK-801, but not by NBQX.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Cortical Spreading Depression; Dizocilpine Maleate; Energy Metabolism; Gene Expression Regulation; Male; Neurons; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate | 1993 |
The AMPA receptor antagonist NBQX exerts antidystonic effects in an animal model of idiopathic dystonia.
Topics: Animals; Cricetinae; Dystonia; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Injections, Intraperitoneal; Male; Mesocricetus; Probenecid; Quinoxalines; Receptors, AMPA; Solutions; Suspensions | 1993 |
Opposite effects of NMDA and AMPA receptor blockade on catalepsy induced by dopamine receptor antagonists.
Topics: Animals; Benzazepines; Catalepsy; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Quinoxalines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Salicylamides | 1993 |
Excitatory amino acid receptor-stimulated phosphoinositide turnover in primary cerebrocortical cultures.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cycloleucine; Female; GTP-Binding Proteins; Kynurenic Acid; Pertussis Toxin; Phosphatidylinositols; Piperazines; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 1993 |
Neuroprotective activity of glutamate receptor antagonists against soman-induced hippocampal damage: quantification with an omega 3 site ligand.
Topics: Animals; Autoradiography; Benzoxazines; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Hippocampus; Isoquinolines; Ligands; Male; Oxazines; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Seizures; Soman | 1993 |
Effect of the non-NMDA receptor antagonist, 2,3-dihydro-6-nitro-7-sulfamoylbenzo(f)quinoxaline, on local cerebral glucose uptake in the limbic forebrain.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glucose; Limbic System; Male; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1993 |
Aniracetam reverses the anticonvulsant action of NBQX and GYKI 52466 in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Dose-Response Relationship, Drug; Mice; Mice, Inbred DBA; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Phrenic and sympathetic nerve responses to glutamergic blockade during normoxia and hypoxia.
Topics: Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Hypercapnia; Hypoxia; Male; Phrenic Nerve; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 1993 |
Influence of combined treatment with NMDA and non-NMDA receptor antagonists on electroconvulsions in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Drug Combinations; Electroshock; Male; Mice; Mice, Inbred Strains; Motor Activity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
Centrally-administered AMPA antagonists increase locomotion in parkinsonian rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Excitatory Amino Acid Antagonists; Male; Mesencephalon; Microinjections; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Substantia Nigra | 1995 |
NMDA receptor-mediated transmission of carotid body chemoreceptor input to expiratory bulbospinal neurones in dogs.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Carotid Body; Dogs; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Male; Medulla Oblongata; Microinjections; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Spinal Cord; Stimulation, Chemical; Synaptic Transmission; Vagotomy | 1995 |
NBQX, an improved non-NMDA antagonist studied in retinal ganglion cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Ambystoma; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; In Vitro Techniques; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells | 1995 |
A dose-response study of neuroprotection using the AMPA antagonist NBQX in rat focal cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1996 |
Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Female; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Time Factors | 1996 |
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus | 1996 |
Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels.
Topics: Animals; Autoradiography; Brain Injuries; Calcium; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ion Channels; Male; Necrosis; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1996 |
Neuroprotective effects of NBQX on hypoxia-induced neuronal damage in rat hippocampus.
Topics: Analysis of Variance; Animals; Excitatory Amino Acid Antagonists; Hippocampus; Histocytochemistry; Hypoxia, Brain; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, Kainic Acid | 1995 |
Pharmacological discrimination of GluR5 and GluR6 kainate receptor subtypes by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahyd roisdoquinoline-3 carboxylic-acid.
Topics: Animals; Cell Line; Ganglia, Spinal; Humans; Isoquinolines; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tetrazoles | 1996 |
Components of glial responses to exogenous and synaptic glutamate in rat hippocampal microcultures.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Microglia; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tacrine | 1996 |
The AMPA antagonist NBQX provides partial protection of rat cerebellar Purkinje cells after cardiac arrest and resuscitation.
Topics: Animals; Cerebellum; Excitatory Amino Acid Antagonists; Heart Arrest; Immunohistochemistry; Male; Purkinje Cells; Quinoxalines; Rats; Resuscitation | 1995 |
Effect of coadministration of glutamate receptor antagonists and dopaminergic agonists on locomotion in monoamine-depleted rats.
Topics: Animals; Biogenic Monoamines; Bromocriptine; Dizocilpine Maleate; Dopamine Agonists; Drug Combinations; Excitatory Amino Acid Antagonists; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 1995 |
Neuroprotection after several days of mild, drug-induced hypothermia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain; Brain Ischemia; Gerbillinae; Hypothermia, Induced; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 1996 |
Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atrophy; Body Weight; Corticosterone; Cyanoketone; Dendrites; Excitatory Amino Acid Antagonists; Hippocampus; Male; Neurons; Organ Size; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stress, Physiological | 1995 |
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.
Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating | 1996 |
Potent and long-lasting anticonvulsant effects of 1-naphthylacetyl spermine, an analogue of Joro spider toxin, against amygdaloid kindled seizures in rats.
Topics: Amygdala; Animals; Anticoagulants; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Kindling, Neurologic; Male; Neurotoxins; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Spermine; Spider Venoms | 1996 |
3-Nitropropionic acid exacerbates [3H]GABA release evoked by glucose deprivation in rat striatal slices.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Hypoglycemia; Isotope Labeling; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Sodium Channels; Tritium | 1996 |
A unitary non-NMDA receptor short subunit from Xenopus: DNA cloning and expression.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Consensus Sequence; DNA, Complementary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Molecular Sequence Data; Molecular Weight; Peptide Chain Initiation, Translational; Quinoxalines; Receptors, Glutamate; Receptors, Kainic Acid; Recombinant Fusion Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Temperature; Thiocyanates; Xenopus laevis; Xenopus Proteins | 1996 |
Prevention of trauma-induced neurodegeneration in infant rat brain.
Topics: Animals; Brain Injuries; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Wounds and Injuries | 1996 |
Allosteric interactions between cyclothiazide and AMPA/kainate receptor antagonists.
Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Drug Interactions; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 1996 |
Evaluation of cardiorespiratory parameters in rats after spinal cord trauma and treatment with NBQX, an antagonist of excitatory amino acid receptors.
Topics: Animals; Blood Pressure; Carbon Dioxide; Excitatory Amino Acid Antagonists; Female; Heart Rate; Oxygen; Partial Pressure; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reference Values; Respiration; Spinal Cord Injuries | 1996 |
Removal of extracellular chloride suppresses transmitter release from photoreceptor terminals in the mudpuppy retina.
Topics: Animals; Cell Polarity; Chlorides; Culture Media; Electrophysiology; Excitatory Amino Acid Antagonists; Extracellular Space; Hypertonic Solutions; In Vitro Techniques; Membrane Potentials; Necturus maculosus; Neurotransmitter Agents; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Presynaptic Terminals; Quinoxalines; Retina | 1996 |
Hyperosmotic activation of transmitter release from presynaptic terminals onto retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Ambystomatidae; Amino Acids; Animals; Anticonvulsants; Cadmium; Cobalt; Convulsants; Excitatory Amino Acid Antagonists; Light; Membrane Potentials; Neurotransmitter Agents; Organ Culture Techniques; Osmotic Pressure; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Retinal Ganglion Cells; Strychnine; Sucrose | 1995 |
Extended studies on the effect of glutamate antagonists on ischemic CA-1 damage.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Neurons; Premedication; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors.
Topics: Cell Line; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Kainic Acid; L-Lactate Dehydrogenase; Ligands; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins | 1996 |
Excitotoxic damage in global ischemia.
Topics: Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Microdialysis; Neurotoxins; Quinoxalines | 1996 |
N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Male; N-Methylaspartate; Neurons; Peripheral Nerve Injuries; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
Pharmacological characterization of AMPA-induced biting behaviour in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Novel AMPA receptor antagonists: synthesis and structure-activity relationships of 1-hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H)- quinoxalinedione and related compounds.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Antagonists; Hydroxylation; Imidazoles; Molecular Structure; Quinoxalines; Rats; Receptors, AMPA; Structure-Activity Relationship; Tritium | 1996 |
The mechanism by which NBQX enhances NMDA currents in retinal ganglion cells.
Topics: Animals; Chlorides; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Light; N-Methylaspartate; Neurotransmitter Agents; Picrotoxin; Quinoxalines; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Sucrose; Synaptic Transmission; Urodela | 1996 |
Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain.
Topics: Animals; Apoptosis; Autoradiography; Deoxyuracil Nucleotides; Dizocilpine Maleate; DNA Fragmentation; DNA Nucleotidylexotransferase; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Techniques; Male; Nucleic Acid Hybridization; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1996 |
Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Kainic Acid; Oocytes; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA; Xenopus laevis | 1996 |
Intrathecal blockade of both NMDA and non-NMDA receptors attenuates the exercise pressor reflex in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Heart Rate; Injections, Spinal; Mechanoreceptors; Muscle Contraction; Muscle, Skeletal; Physical Exertion; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Respiratory Mechanics; Stereotaxic Techniques; Sympathetic Nervous System; Synaptic Transmission | 1996 |
Glutamatergic and GABAergic postsynaptic responses of striatal spiny neurons to intrastriatal and cortical stimulation recorded in slice preparations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Synaptic Transmission | 1996 |
N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; N-Methylaspartate; Prosencephalon; Protein Precursors; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1995 |
Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain.
Topics: Animals; Animals, Newborn; Brain; Dizocilpine Maleate; Evaluation Studies as Topic; Excitatory Amino Acid Antagonists; Exploratory Behavior; Infusion Pumps, Implantable; Injections, Intraperitoneal; Male; Maze Learning; Neuroprotective Agents; Pilot Projects; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 1996 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Muscarinic activation reduces changes in [Ca2+]o evoked by stimulation of Schaffer collaterals during blocked synaptic transmission in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Carbachol; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Muscarinic Agonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; Synaptic Transmission | 1996 |
A role for presynaptic AMPA receptors in the enhancement of neuronal glutamate release by kainic acid.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurons; Prosencephalon; Quinoxalines; Rats; Receptors, AMPA; Receptors, Presynaptic | 1996 |
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists.
Topics: Animals; Behavior, Animal; Chronic Disease; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hyperalgesia; Ischemia; Motor Activity; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries | 1996 |
Strychnine-sensitive modulation is selective for non-noxious somatosensory input in the spinal cord of the rat.
Topics: Anesthesia, General; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Nerve Fibers; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine | 1996 |
Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Gerbillinae; Indazoles; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Quinoxalines | 1996 |
Functional partial agonism at ionotropic excitatory amino acid receptors.
Topics: Alanine; Animals; Binding, Competitive; Cerebral Cortex; Dinucleoside Phosphates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Models, Neurological; N-Methylaspartate; Propionates; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate | 1996 |
Determination of intracellular Ca2+ concentration can be a useful tool to predict neuronal damage and neuroprotective properties of drugs.
Topics: Amantadine; Analysis of Variance; Animals; Biomarkers; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kinetics; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Cyanide; Telencephalon; Time Factors | 1996 |
Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Isotopes; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Deferoxamine; Deuterium; Dizocilpine Maleate; Fetus; Gas Chromatography-Mass Spectrometry; Glucose; Hydrogen Peroxide; Iron; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Pentose Phosphate Pathway; Putamen; Quinoxalines; Rats | 1996 |
Monitoring the temporal and spatial activation pattern of astrocytes in focal cerebral ischemia using in situ hybridization to GFAP mRNA: comparison with sgp-2 and hsp70 mRNA and the effect of glutamate receptor antagonists.
Topics: Animals; Astrocytes; Brain Ischemia; Clusterin; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycoproteins; HSP70 Heat-Shock Proteins; In Situ Hybridization; Male; Molecular Chaperones; Quinoxalines; Rats; Rats, Inbred F344; RNA, Messenger; Time Factors | 1996 |
Distinct short-term plasticity at two excitatory synapses in the hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Nerve Fibers; Neuronal Plasticity; Neurons; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1996 |
Studies of synaptic transmission in vivo: indirect versus direct effects of (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid/kainate antagonists on rat spinal sensory responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Iontophoresis; Male; Microelectrodes; N-Methylaspartate; Neurons, Afferent; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord; Synaptic Transmission | 1996 |
Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biguanides; Brain Mapping; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Kynurenic Acid; Lung; Male; N-Methylaspartate; Nerve Fibers; Neurons; Pressoreceptors; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus; Vagus Nerve | 1996 |
Pharmacology and regional distribution of the binding of 6-[3H]nitro-7-sulphamoylbenzo[f]-quinoxaline-2,3-dione to rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Excitatory Amino Acid Antagonists; Female; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Tritium | 1996 |
Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Felbamate; Female; Injections, Intraventricular; Ion Channel Gating; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; Motor Activity; Phenylcarbamates; Potassium Channels; Propylene Glycols; Quinoxalines | 1996 |
Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D-[3H] aspartic acid in cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin; Tritium | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4- isoxazoleproprionate (AMPA) glutamate-receptor antagonists have different interactions with the discriminative stimuli of abused drugs.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Conditioning, Operant; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Morphine; Narcotic Antagonists; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1996 |
Amphetamine induction of c-fos in the nucleus accumbens is not inhibited by glutamate antagonists.
Topics: Amphetamines; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Nucleus Accumbens; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley | 1995 |
Phenylglycines can evoke quisqualate-primed depolarizations in rat cingulate cortex: an effect associated with [3H]DL-AP4 uptake.
Topics: Aminobutyrates; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Gyrus Cinguli; Osmolar Concentration; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Tritium | 1996 |
Three types of postsynaptic glutamatergic receptors are activated in DMNX neurons upon stimulation of NTS.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Brain; Concanavalin A; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solitary Nucleus; Synapses; Vagus Nerve | 1996 |
Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors.
Topics: Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Pimelic Acids; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Pharmacologic blockade of non-NMDA receptors at deep prepiriform cortex attenuates heat shock protein expression in global ischemia.
Topics: Animals; Biomarkers; Brain Ischemia; Cerebral Cortex; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Hippocampus; HSP72 Heat-Shock Proteins; Immunohistochemistry; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
NMDA as well as non-NMDA receptors in phrenic nucleus mediate respiratory effects of carotid chemoreflex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carotid Body; Chemoreceptor Cells; Drug Combinations; Excitatory Amino Acid Antagonists; Male; Microinjections; Neck; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Spinal Cord; Stimulation, Chemical | 1997 |
Effects of the AMPA-receptor antagonist, NBQX, on neuron loss in dentate hilus of the hippocampal formation after 8, 10, or 12 min of cerebral ischemia in the rat.
Topics: Animals; Brain Ischemia; Cell Death; Dentate Gyrus; Excitatory Amino Acid Antagonists; Hippocampus; Ligation; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Shock; Somatostatin; Time Factors | 1997 |
Neuroprotection with NBQX in rat focal cerebral ischemia. Effects on ADC probability distribution functions and diffusion-perfusion relationships.
Topics: Animals; Body Water; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Cerebral Infarction; Diffusion; Excitatory Amino Acid Antagonists; Magnetic Resonance Imaging; Male; Nerve Tissue Proteins; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
AMPA receptors modulate dopamine release in the striatum, as measured by brain microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrodotoxin | 1997 |
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1997 |
A crucial role of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptors in piriform and perirhinal cortex for the initiation and propagation of limbic motor seizures.
Topics: Animals; Male; Motor Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Seizures | 1997 |
Morphological and electrophysiological characterization of layer III cells of the medial entorhinal cortex of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Neurons; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 1997 |
Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage.
Topics: Animals; Cells, Cultured; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Memantine; Neurons; Neurotoxins; Nimodipine; Quinoxalines; Rats; Rats, Inbred F344 | 1996 |
Posttetanic excitation mediated by GABA(A) receptors in rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ethoxzolamide; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Interneurons; Ketamine; Male; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Tetany | 1997 |
Deep prepiriform cortex modulates neuronal cell death in global ischemia.
Topics: Animals; Brain Ischemia; Cell Count; Cell Death; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microinjections; Neurons; Neuroprotective Agents; Olfactory Pathways; Premedication; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotaxic Techniques | 1997 |
Detrimental effects of exogenous glutamate on spinal cord neurons during brief ischemia in vivo.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Ischemia; Neurons; Paraplegia; Paresis; Quinoxalines; Rabbits; Spinal Cord | 1997 |
Non-NMDA but not NMDA blockade at deep prepiriform cortex protects against hippocampal cell death in status epilepticus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cell Death; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Neuroprotective Agents; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reproducibility of Results; Status Epilepticus | 1997 |
A new extracellular multirecording system for electrophysiological studies: application to hippocampal organotypic cultures.
Topics: Animals; Bicuculline; Dexamethasone; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glucocorticoids; Hippocampus; Kainic Acid; Microelectrodes; Organ Culture Techniques; Quinoxalines; Rats; Reproducibility of Results; Tetrodotoxin | 1997 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
Regional measurements of NO formed in vivo during brain ischemia.
Topics: Analysis of Variance; Animals; Benzimidazoles; Brain; Calcium Channel Blockers; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Gerbillinae; Hippocampus; Indazoles; Ischemic Attack, Transient; Male; Nitric Oxide; Nitric Oxide Synthase; Organ Specificity; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reference Values | 1997 |
Transporters buffer synaptically released glutamate on a submillisecond time scale.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamic Acid; Hippocampus; Kinetics; Kynurenic Acid; Lithium; Models, Neurological; Neurons; Quinoxalines; Rats; Receptors, AMPA; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors | 1997 |
Prevention of normally occurring and deafferentation-induced neuronal death in chick brainstem auditory neurons by periodic blockade of AMPA/kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Auditory Pathways; Brain Stem; Cell Death; Cell Survival; Chick Embryo; Excitatory Amino Acid Antagonists; Kinetics; Neurons; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Time Factors | 1997 |
Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Cortical Spreading Depression; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dizocilpine Maleate; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Functional Laterality; Hippocampus; Immunohistochemistry; In Situ Hybridization; Ischemic Attack, Transient; Isoenzymes; Male; Membrane Proteins; Neurons; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcription, Genetic | 1997 |
Glycine causes increased excitability and neurotoxicity by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoxazines; Cell Death; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Neurotoxins; Organ Culture Techniques; Oxazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Anticonvulsant action of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline in immature rats: comparison with the effects on motor performance.
Topics: Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Male; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Task Performance and Analysis | 1997 |
Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dopamine Agonists; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Stereotyped Behavior | 1997 |
Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Delayed antagonism of AMPA/kainate receptors reduces long-term functional deficits resulting from spinal cord trauma.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Microinjections; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Serotonin; Spinal Cord Injuries; Time Factors | 1997 |
Domoic acid neurotoxicity in cultured cerebellar granule neurons is mediated predominantly by NMDA receptors that are activated as a consequence of excitatory amino acid release.
Topics: Animals; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Regulation of muscarinic acetylcholine receptor-mediated synaptic responses by adenosine receptors in the rat hippocampus.
Topics: Adenosine; Adenosine Kinase; Animals; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Parasympatholytics; Parasympathomimetics; Physostigmine; Quinoxalines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P1; Synaptic Membranes; Synaptic Transmission; Xanthines | 1997 |
Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Pathways; Neurons; Optic Nerve; Oxytocin; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Suprachiasmatic Nucleus; Supraoptic Nucleus; Vasopressins | 1997 |
Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals.
Topics: Animals; Brain Ischemia; Caudate Nucleus; Cerebral Cortex; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Immunohistochemistry; Male; Microtubule-Associated Proteins; Nitrogen Oxides; Oligodendroglia; Quinoxalines; Rats; Rats, Inbred F344; Spin Labels; tau Proteins | 1997 |
Neuroprotective effect of YM90K, an AMPA-receptor antagonist, against delayed neuronal death induced by transient global cerebral ischemia in gerbils and rats.
Topics: Animals; Body Temperature; Brain Ischemia; Cell Death; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar | 1997 |
Ultrastructural and biochemical studies on the neuroprotective effects of excitatory amino acid antagonists in the ischemic rat retina.
Topics: Animals; Choline O-Acetyltransferase; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Ischemia; Kynurenic Acid; Light; Microscopy, Electron; Neuroprotective Agents; Quinoxalines; Radiation Injuries, Experimental; Rats; Retina; Retinal Vein Occlusion; Retinal Vessels; Rose Bengal | 1997 |
GYKI 53665, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Spatiotemporal patterns of gamma frequency oscillations tetanically induced in the rat hippocampal slice.
Topics: Action Potentials; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Interneurons; Male; Organ Culture Techniques; Periodicity; Potassium; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Differential impact of miniature synaptic potentials on the soma and dendrites of pyramidal neurons in vivo.
Topics: Anesthesia; Animals; Barbiturates; Cats; Dendrites; Electroencephalography; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Membrane Potentials; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Synapses; Synaptic Membranes; Tetrodotoxin | 1997 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Consciousness; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; N-Methylaspartate; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1997 |
Recurrent excitatory postsynaptic potentials induced by synchronized fast cortical oscillations.
Topics: Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Models, Neurological; Nerve Net; Neural Conduction; Periodicity; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetany | 1997 |
Regulation of gonadotropin-releasing hormone and luteinizing hormone secretion by AMPA receptors. Evidence for a physiological role of AMPA receptors in the steroid-induced luteinizing hormone surge.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Ovariectomy; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzolamide; Bicarbonates; Carbonic Anhydrases; Enzyme Inhibitors; Ethoxzolamide; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Models, Neurological; Pentobarbital; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 1997 |
Development of intrinsic and synaptic properties in a forebrain nucleus essential to avian song learning.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Birds; Excitatory Amino Acid Antagonists; GABA Antagonists; Learning; Long-Term Potentiation; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Picrotoxin; Prosencephalon; Quinoxalines; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Vocalization, Animal | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Double dissociation between the involvement of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in startle increases produced by conditioned versus unconditioned fear.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Afferent Pathways; Amygdala; Animals; Anxiety; Avoidance Learning; Conditioning, Classical; Darkness; Excitatory Amino Acid Antagonists; Fear; Hypothalamus; Male; Photic Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex, Startle | 1997 |
Glutamate excitation of oxytocin neurones in vitro involves predominantly non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Enkephalin, Leucine-2-Alanine; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Neurons; Oxytocin; Quinoxalines; Rats; Rats, Wistar | 1997 |
Enhancement of contextual fear-conditioning by putative (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor modulators and N-methyl-D-aspartate (NMDA) receptor antagonists in DBA/2J mice.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Classical; Cues; Excitatory Amino Acid Antagonists; Fear; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nootropic Agents; Pyrrolidines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Pharmacology of the AMPA antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo-(F)-quinoxaline.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Brain Injuries; Brain Ischemia; Cerebral Cortex; Convulsants; Excitatory Amino Acid Antagonists; Exploratory Behavior; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Neuroprotective Agents; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Seizures | 1997 |
Neuronal damage and MAP2 changes induced by the glutamate transport inhibitor dihydrokainate and by kainate in rat hippocampus in vivo.
Topics: Animals; Biological Transport; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Microtubule-Associated Proteins; Neurons; Quinoxalines; Rats; Rats, Wistar | 1997 |
Some behavioral effects of AMPA/kainate receptor agonist and antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Conflict, Psychological; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 1997 |
Activation of brain nitric oxide synthase in depolarized human temporal cortex slices: differential role of voltage-sensitive calcium channels.
Topics: Alanine; Arginine; Calcium Channel Blockers; Calcium Channels; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mecamylamine; Nicotinic Antagonists; Nitric Oxide Synthase; Nitroarginine; Potassium; Potassium Chloride; Quinoxalines; Temporal Lobe | 1997 |
Effect of thiol group modification on 3[H]-NBQX binding in rat cortical membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Chloromercuribenzoates; Disulfides; Dithiothreitol; Female; p-Chloromercuribenzoic Acid; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sulfhydryl Compounds | 1997 |
Sublethal oxygen-glucose deprivation alters hippocampal neuronal AMPA receptor expression and vulnerability to kainate-induced death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Glucose; Hippocampus; Ischemic Preconditioning; Kainic Acid; Nerve Tissue Proteins; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Spider Venoms | 1997 |
Measurement of intracellular free zinc in living cortical neurons: routes of entry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Ionophores; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Neurons; Nimodipine; Quinoxalines; Sodium-Calcium Exchanger; Zinc | 1997 |
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E | 1997 |
Effects of serotonin on synaptic and intrinsic properties of rat subicular neurons in vitro.
Topics: Animals; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Serotonin; Synapses | 1997 |
Spinal pharmacology of tactile allodynia in diabetic rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Imidazoles; Injections, Spinal; Medetomidine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin | 1997 |
The glutamate receptor/NO/cyclic GMP pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with GABA and the behavioural consequences.
Topics: Animals; Behavior, Animal; Benzothiadiazines; Cyclic GMP; Diuretics; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Nitric Oxide; Nitric Oxide Synthase; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors | 1997 |
In vivo microdialysis study of GABA(A) and GABA(B) receptors modulating the glutamate receptor/NO/cyclic GMP pathway in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cyclic GMP; Epilepsy; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Hippocampus; Microdialysis; Nitric Oxide; Quinoxalines; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1997 |
Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stereotyped Behavior | 1997 |
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission.
Topics: Animals; Arachidonic Acids; Brain; Calcium; Calcium Channel Blockers; Cannabinoids; Cerebellum; Cerebral Cortex; Dronabinol; Endocannabinoids; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Oocytes; Pertussis Toxin; Picrotoxin; Polyunsaturated Alkamides; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Virulence Factors, Bordetella; Wasp Venoms; Xenopus laevis | 1998 |
Activation of cerebellar climbing fibers increases cerebellar blood flow: role of glutamate receptors, nitric oxide, and cGMP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Harmaline; Male; Nerve Fibers; Nitric Oxide; Nitroarginine; Oxygen; Partial Pressure; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Tetrodotoxin; Ultrasonography, Doppler, Transcranial | 1998 |
The role of excitatory amino acids in airway reflex responses in anesthetized dogs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia, General; Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Chloralose; Dogs; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Heart Rate; Lung Volume Measurements; Male; Muscle, Smooth; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Trachea | 1997 |
Cerebellar vascular and synaptic responses in normal mice and in transgenics with Purkinje cell dysfunction.
Topics: Action Potentials; Animals; Blood Flow Velocity; Cerebellum; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Kynurenic Acid; Laser-Doppler Flowmetry; Mice; Mice, Transgenic; Microscopy, Electron; Nitric Oxide Synthase; Nitroarginine; Purkinje Cells; Quinoxalines; Receptors, AMPA; Synapses | 1998 |
Intrinsic circuitry of the superior colliculus: pharmacophysiological identification of horizontally oriented inhibitory interneurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Ferrets; In Vitro Techniques; Interneurons; Male; Quinoxalines; Saccades; Superior Colliculi | 1998 |
Distribution and properties of kainate receptors distinct in the CA3 region of the hippocampus of the guinea pig.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; Hippocampus; Kainic Acid; Microinjections; Pressure; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Time Factors | 1998 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline (NBQX) increases fibroblast growth factor mRNA levels after contusive spinal cord injury.
Topics: Animals; Contusions; Excitatory Amino Acid Antagonists; Fibroblast Growth Factors; Laminectomy; Quinoxalines; Rats; RNA, Messenger; Spinal Cord Injuries; Tissue Distribution | 1998 |
Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Nociceptors; Pain, Postoperative; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Metabotropic Glutamate; Spinal Cord | 1998 |
Activation of non-NMDA receptors stimulates acetylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1998 |
Pharmacological characterization of the human ionotropic glutamate receptor subtype GluR3 stably expressed in mammalian cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Binding, Competitive; Brain; Cells, Cultured; Diuretics; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Kidney; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1998 |
Respiratory effects of halothane and AMPA receptor antagonist synergy in rats.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Halothane; Hemodynamics; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Respiratory Mechanics | 1998 |
Effects of AMPA receptor antagonists on dopamine-mediated behaviors in mice.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Dopamine; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Mice; Motor Activity; Quinoxalines; Receptors, AMPA; Stereotyped Behavior; Tetrazoles | 1998 |
Excitatory amino acid antagonists alleviate convulsive and toxic properties of lindane in mice.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Felbamate; Hexachlorocyclohexane; Insecticides; Lethal Dose 50; Male; Mice; Phenylcarbamates; Propylene Glycols; Quinoxalines; Seizures | 1998 |
The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury.
Topics: Animals; Benzothiadiazines; Brain Ischemia; Cells, Cultured; Diazoxide; Diuretics; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Nerve Degeneration; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1998 |
Behavioral effects of NBQX, a competitive antagonist of the AMPA receptors.
Topics: Animals; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 1998 |
Excitatory amino acid receptor antagonists decrease hypoxia induced increase in extracellular dopamine in striatum of newborn piglets.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Hypoxia; Oxygen; Oxygen Consumption; Pressure; Quinoxalines; Receptors, Amino Acid; Swine | 1998 |
Modulation of neuronal activity by glial cells in the retina.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Astrocytes; Bicuculline; Calcium; Cell Communication; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; Male; Neurotransmitter Agents; Photic Stimulation; Quinoxalines; Rats; Rats, Inbred Strains; Retinal Ganglion Cells; Strychnine; Thapsigargin | 1998 |
Role of cerebral blood flow in seizures from hyperbaric oxygen exposure.
Topics: Analysis of Variance; Animals; Cerebrovascular Circulation; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperbaric Oxygenation; Ketamine; Male; Nitric Oxide Synthase; Nitroarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 1998 |
Protective effect of GV150526A on the glutamate-induced changes in basal and electrically-stimulated cytosolic Ca++ in primary cultured cerebral cortical cells.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Indoles; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
AMPA and NMDA receptor-dependent spinal LTP after nociceptive tetanic stimulation.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Muscle Contraction; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1998 |
The tetrameric structure of a glutamate receptor channel.
Topics: Binding Sites; Cell Line; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Humans; Ligands; Macromolecular Substances; Models, Biological; Patch-Clamp Techniques; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Recombinant Fusion Proteins | 1998 |
Involvement of AMPA receptors in posterior locomotor activity in the rabbit: an in vivo study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Antagonists; Hindlimb; Motor Activity; Quinoxalines; Rabbits; Receptors, AMPA | 1998 |
Galanin stimulates the N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in vivo in the rat ventral hippocampus.
Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Galanin; Hippocampus; Locomotion; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptide Fragments; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1998 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
Respiratory effects of glutamate receptor antagonists in neonate and adult mammals.
Topics: Age Factors; Animals; Animals, Newborn; Apnea; Cats; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Plethysmography; Pulmonary Ventilation; Quinoxalines; Receptors, Glutamate; Species Specificity | 1998 |
Respiratory depression produced by intravenously administered NBQX.
Topics: Animals; Apnea; Atrial Function; Blood Pressure; Cats; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heart Rate; Injections, Intravenous; Phrenic Nerve; Quinoxalines; Respiratory Insufficiency; Respiratory Physiological Phenomena; Respiratory System | 1998 |
Characterization of neuronal migration disorders in neocortical structures. II. Intracellular in vitro recordings.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Brain Diseases; Cell Movement; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Membrane Potentials; Neocortex; Neurons; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1998 |
Limbic gamma rhythms. II. Synaptic and intrinsic mechanisms underlying spike doublets in oscillating subicular neurons.
Topics: Action Potentials; Animals; Bicuculline; Dendrites; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Limbic System; Models, Neurological; Neocortex; Nerve Net; Neural Conduction; Oscillometry; Phosphinic Acids; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1998 |
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.
Topics: Animals; Benzodiazepines; Excitatory Amino Acid Antagonists; Formaldehyde; Humans; Isoquinolines; Male; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Tetrazoles | 1998 |
AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons.
Topics: Animals; Benzothiadiazines; Cell Survival; Cells, Cultured; Dioxoles; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neurons; Neurotoxins; Piperidines; Quinoxalines; Rats; Receptors, AMPA | 1998 |
EAA receptors in the dorsomedial hypothalamic area mediate the cardiovascular response to activation of the amygdala.
Topics: Amygdala; Animals; Bicuculline; Brain Mapping; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Heart Rate; Kynurenic Acid; Male; Microinjections; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Time Factors | 1998 |
Analysing functional connectivity in brain slices by a combination of infrared video microscopy, flash photolysis of caged compounds and scanning methods.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Microscopy, Video; Photolysis; Quinoxalines; Rats; Receptors, Glutamate; Somatosensory Cortex; Tetrodotoxin | 1998 |
Genesis of spontaneous rhythmic motor patterns in the lumbosacral spinal cord of neonate mouse.
Topics: Animals; Animals, Newborn; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Locomotion; Magnesium; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Periodicity; Pregnancy; Quinoxalines; Spinal Cord | 1998 |
Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Glycine; Male; Nerve Fibers; Neural Inhibition; Patch-Clamp Techniques; Protein Kinase C; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission; Type C Phospholipases | 1998 |
Low-affinity kainate receptors and long-lasting depression of NMDA-receptor-mediated currents in rat superficial dorsal horn.
Topics: Action Potentials; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Glutamic Acid; Indoles; Ion Channel Gating; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Neuroprotective Agents; Oximes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1998 |
Dendrodendritic inhibition in the olfactory bulb is driven by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Magnesium; Male; Neural Inhibition; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Longitudinal distribution of components of excitatory synaptic input to motoneurones during swimming in young Xenopus tadpoles: experiments with antagonists.
Topics: Animals; Cadmium; Convulsants; Dihydro-beta-Erythroidine; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Larva; Motor Neurons; Quinoxalines; Receptors, Nicotinic; Spinal Cord; Strychnine; Swimming; Synapses; Xenopus | 1998 |
In-vitro characterization of YM872, a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Buffers; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Imidazoles; Kainic Acid; Male; Neuroprotective Agents; Oocytes; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Solubility; Xenopus laevis | 1998 |
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E | 1998 |
Glial contribution to glutamate uptake at Schaffer collateral-commissural synapses in the hippocampus.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Membrane Potentials; Nerve Fibers; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Temperature | 1998 |
Suppression of NMDA receptor function using antisense DNA block ocular dominance plasticity while preserving visual responses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; DNA, Antisense; Excitatory Amino Acid Antagonists; Ferrets; Neuronal Plasticity; Oligonucleotide Probes; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vision, Binocular; Visual Pathways | 1998 |
Serotonin reduces polysynaptic inhibition via 5-HT1A receptors in the superficial entorhinal cortex.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses | 1998 |
Non-NMDA and NMDA receptors in the synaptic pathway between area postrema and nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Brain Stem; Cardiovascular System; Cerebral Ventricles; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Male; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synaptic Transmission; Yohimbine | 1998 |
Characterization of the mechanism of action of tachykinins in rat striatal cholinergic interneurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Chelating Agents; Corpus Striatum; Diazonium Compounds; Electric Stimulation; Estrenes; Excitatory Amino Acid Antagonists; Guanosine 5'-O-(3-Thiotriphosphate); Interneurons; Male; Membrane Potentials; Patch-Clamp Techniques; Phenoxyacetates; Phosphodiesterase Inhibitors; Photochemistry; Piperidines; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Synaptic Transmission; Tachykinins; Tetrodotoxin | 1998 |
Calcium influx via ionotropic glutamate receptors causes long lasting inhibition of metabotropic glutamate receptor-coupled phosphoinositide hydrolysis.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GTP-Binding Proteins; Hydrolysis; Kainic Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium Fluoride | 1998 |
Multiple classes of the oligodendrocyte lineage are highly vulnerable to excitotoxicity.
Topics: Animals; Astrocytes; Cell Lineage; Coculture Techniques; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Immunohistochemistry; Mice; Oligodendroglia; Prosencephalon; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid | 1998 |
Increases in levels of brain-derived neurotrophic factor mRNA and its promoters after transient forebrain ischemia in the rat brain.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Dizocilpine Maleate; DNA Probes; Excitatory Amino Acid Antagonists; Exons; Gene Expression; Hippocampus; In Situ Hybridization; Ischemic Attack, Transient; Male; Mice; Promoter Regions, Genetic; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution | 1998 |
Relationship between anticonvulsant activity and plasma level of some 2,3-benzodiazepines in genetically epilepsy-prone rats.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Motor Activity; Motor Skills Disorders; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1998 |
Mediodorsal thalamus plays a critical role in the development of limbic motor seizures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Muscimol; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Time Factors; Vigabatrin | 1998 |
Development of calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining.
Topics: Animals; Calcium; Cells, Cultured; Cobalt; Concanavalin A; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Mice; Neocortex; Neurons; Permeability; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Staining and Labeling | 1998 |
[Glutamate neurotoxicity during spinal cord ischemia--neuroprotective effects of glutamate receptor antagonists].
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Ischemia; Neuroprotective Agents; Quinoxalines; Rabbits; Spinal Cord | 1998 |
Effect of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline on methamphetamine- and cocaine-induced behavioral sensitization.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Male; Methamphetamine; Premedication; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereotypic Movement Disorder | 1998 |
Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia.
Topics: Animals; Blotting, Western; Calpain; Cerebral Infarction; Cytoskeleton; Excitatory Amino Acid Antagonists; Immunohistochemistry; Ischemic Attack, Transient; Male; Microtubule-Associated Proteins; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, Glutamate; Spectrin; Synaptic Transmission; tau Proteins | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzoates; Calcium; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Magnesium; Membrane Potentials; Microscopy, Confocal; Neurons; Nifedipine; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1998 |
AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Motivation; Motor Activity; Quinoxalines; Receptors, AMPA; Self Administration | 1998 |
AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice.
Topics: Amphetamine; Animals; Behavior, Animal; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; Quinoxalines; Receptors, AMPA | 1998 |
The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Receptors, GABA; Synapses; Synaptic Transmission | 1998 |
Assessing the roles of glutamatergic and cholinergic synaptic drive in the control of fictive swimming frequency in young Xenopus tadpoles.
Topics: Animals; Cholinergic Fibers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Larva; N-Methylaspartate; Neural Inhibition; Quinoxalines; Receptors, Nicotinic; Swimming; Synapses; Xenopus | 1998 |
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline reduces glial loss and acute white matter pathology after experimental spinal cord contusion.
Topics: Animals; Brain; Cell Death; Contusions; Excitatory Amino Acid Antagonists; Female; Hindlimb; Immunohistochemistry; Neuroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 1999 |
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.
Topics: Animals; Apoptosis; Brain; Calcium Channel Blockers; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Haloperidol; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Muscarinic Antagonists; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1999 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture Techniques; Cytosol; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Microscopy, Fluorescence; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Sodium; Veratridine | 1998 |
Non-N-methyl-D-aspartate receptors may mediate the transmission of emetic signals between visceral vagal afferents and the solitary nucleus in dogs.
Topics: Anesthesia; Animals; Decerebrate State; Dizocilpine Maleate; Dogs; Electric Stimulation; Excitatory Amino Acid Antagonists; Lingual Nerve; Phrenic Nerve; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Salivation; Solitary Nucleus; Synaptic Transmission; Vagus Nerve; Vomiting | 1998 |
Synaptic reorganization in explanted cultures of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Dentate Gyrus; Dextrans; Excitatory Postsynaptic Potentials; Fluoresceins; Hippocampus; Intracellular Fluid; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Rhodamines; Synapses; Tetrodotoxin | 1999 |
Postsynaptically silent synapses in single neuron cultures.
Topics: Animals; Animals, Newborn; Cells, Cultured; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Extracellular reduced glutathione increases neuronal vulnerability to combined chemical hypoxia and glucose deprivation.
Topics: Animals; Cells, Cultured; Dizocilpine Maleate; Edetic Acid; Excitatory Amino Acid Antagonists; Glucose; Glutathione; Glutathione Disulfide; Hypoxia, Brain; Mercaptoethanol; Mice; Neurons; Oxidation-Reduction; Quinoxalines; Synaptic Transmission | 1999 |
Pharmacological profile of the isomers of the GluR-specific agonist ATPA.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Kynurenic Acid; Propionates; Quinoxalines; Rats; Receptors, Glutamate; Stereoisomerism | 1998 |
The bacterial endotoxin lipopolysaccharide causes rapid inappropriate excitation in rat cortex.
Topics: Adenosine; Age Factors; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Lipopolysaccharides; Male; Neuroprotective Agents; Norepinephrine; Organ Culture Techniques; Parietal Lobe; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sympathomimetics; Tritium | 1999 |
Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures.
Topics: Animals; Benzodiazepines; Blotting, Western; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Neocortex; Neuromuscular Depolarizing Agents; Neurotoxins; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1999 |
A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Binding, Competitive; Cell Death; Electroshock; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; GABA Agents; Kindling, Neurologic; Kinetics; Male; Mice; Mice, Inbred Strains; Neurons; Phenylurea Compounds; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Temporal Lobe; Valproic Acid | 1999 |
Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection.
Topics: Aging; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Motor Cortex; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Synaptic Transmission | 1999 |
Expression of long-term potentiation in single wide dynamic range neurons in the rat is sensitive to blockade of glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1999 |
Consequences of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor blockade during status epilepticus in the developing brain.
Topics: Animals; Brain; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Maze Learning; Quinoxalines; Rats; Receptors, AMPA; Status Epilepticus | 1999 |
Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats.
Topics: Animals; Brain Ischemia; Cell Death; Hippocampus; Male; Neurons; Neuroprotective Agents; omega-Conotoxins; Peptides; Quinoxalines; Rats; Rats, Wistar; Time Factors | 1999 |
Synaptic transmission at nicotinic acetylcholine receptors in rat hippocampal organotypic cultures and slices.
Topics: Aconitine; Animals; Bungarotoxins; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Nicotinic Antagonists; Organ Culture Techniques; Picrotoxin; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission; Tubocurarine | 1999 |
Regulation of growth hormone secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in infantile, prepubertal, and adult male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Nitric Oxide; Pituitary Gland; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sexual Maturation | 1999 |
Heparin injection into the adult rat hippocampus induces seizures in the absence of macroscopic abnormalities.
Topics: Animals; Bicuculline; Drug Combinations; Electrophysiology; Heparin; Hippocampus; In Vitro Techniques; Male; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Neurotransmitter; Seizures; Swine; Synapses | 1999 |
Dizocilpine maleate, MK-801, but not 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline, NBQX, prevents transneuronal degeneration of nigral neurons after neurotoxic striatal-pallidal lesion.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Globus Pallidus; Ibotenic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Substantia Nigra | 1999 |
NMDA and non-NMDA receptors mediate responses in the primary gustatory nucleus in goldfish.
Topics: Animals; Brain; Cerebrospinal Fluid; Electric Stimulation; Electrophysiology; Evoked Potentials; Goldfish; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vagus Nerve; Valine | 1999 |
Hypoxia induces c-Fos protein expression in NMDA but not AMPA glutamate receptor labeled neurons within the nucleus tractus solitarii of the conscious rat.
Topics: Air; Amino Acid Sequence; Animals; Cell Hypoxia; Consciousness; Dizocilpine Maleate; Gene Expression Regulation; Male; Molecular Sequence Data; Neurons; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1999 |
Differences in the properties of ionotropic glutamate synaptic currents in oxytocin and vasopressin neuroendocrine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Hypothalamus; In Vitro Techniques; Neurons; Oxytocin; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Synapses; Vasopressins | 1999 |
Biochemical and pharmacological evidence of a functional role of AMPA receptors in motor neuron dysfunction in mnd mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Antibodies; Autoradiography; Blotting, Western; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Mutant Strains; Motor Neurons; Nerve Degeneration; Neurotoxins; Quinoxalines; Receptors, AMPA; Spinal Cord; Tritium | 1999 |
Effects of dopamine agonists and antagonists on optical responses evoked in rat frontal cortex slices after stimulation of the subcortical white matter.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzazepines; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electric Stimulation; Excitatory Amino Acid Antagonists; Frontal Lobe; Nerve Fibers; Organ Culture Techniques; Quinoxalines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Tetrodotoxin | 1999 |
AMPA/kainate-related mechanisms contribute to convulsant and proconvulsant effects of 3-nitropropionic acid.
Topics: Animals; Anticonvulsants; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraventricular; Male; Mice; Mitochondria; N-Methylaspartate; Nitro Compounds; Propionates; Quinoxalines; Receptors, AMPA | 1999 |
SPD 502: a water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cells, Cultured; Cerebral Cortex; Electroshock; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Isoquinolines; Kainic Acid; Kinetics; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Molecular Structure; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pipecolic Acids; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Stereoisomerism; Tetrahydroisoquinolines | 1999 |
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Differential effects of excitatory amino acid receptor antagonism in the ventral respiratory group.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Antagonists; Female; Male; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1999 |
Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Lighting; Male; Mesocricetus; Microinjections; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Synaptic Transmission | 1999 |
Neuroprotection by the alpha2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia.
Topics: Adrenergic alpha-Agonists; Animals; Arterial Occlusive Diseases; Body Weight; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Excitatory Amino Acid Antagonists; Imidazoles; Ischemic Attack, Transient; Male; Medetomidine; Neuroprotective Agents; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar | 1999 |
The concentration of synaptically released glutamate outside of the climbing fiber-Purkinje cell synaptic cleft.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Benzothiadiazines; Cell Membrane; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Kinetics; Models, Biological; Neuroglia; Patch-Clamp Techniques; Probability; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Synapses; Temperature | 1999 |
CNQX but not NBQX prevents expression of amphetamine-induced place preference conditioning: a role for the glycine site of the NMDA receptor, but not AMPA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Operant; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred C57BL; Motor Activity; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1999 |
Neuroprotection of cultured foetal rat hippocampal cells against glucose deprivation: are GABAergic neurons less vulnerable or more sensitive to TCP protection?
Topics: Animals; Cell Survival; Cells, Cultured; Drug Resistance; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Phencyclidine; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Differential roles of ionotropic glutamate receptors in canine medullary inspiratory neurons of the ventral respiratory group.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Inhalation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Capsaicin; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Male; Neurons; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Trigeminal Caudal Nucleus | 1999 |
Glutamate receptor-mediated mechanisms in levodopa-induced motor fluctuations in an experimental model of parkinsonism.
Topics: Animals; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Male; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Rotation; Stereotyped Behavior; Time Factors | 1999 |
Postmortem elevation in extracellular glutamate in the rat hippocampus when brain temperature is maintained at physiological levels: implications for the use of human brain autopsy tissues.
Topics: Animals; Autopsy; Body Temperature Regulation; Brain; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Male; Microdialysis; Postmortem Changes; Quinoxalines; Rats; Rats, Sprague-Dawley; Taurine | 1999 |
The network-selective actions of quinoxalines on the neurocircuitry operations of the rabbit retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Light; Membrane Potentials; Nerve Net; Quinoxalines; Rabbits; Receptors, Glutamate; Retina; Retinal Ganglion Cells; Visual Pathways | 1999 |
Biphasic expression of TGF-beta1 mRNA in the rat brain following permanent occlusion of the middle cerebral artery.
Topics: Animals; Arterial Occlusive Diseases; Brain; Cerebral Arteries; Chronic Disease; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Inbred F344; RNA, Messenger; Transforming Growth Factor beta | 1999 |
Effects of YM90K, a selective AMPA receptor antagonist, on amygdala-kindling and long-term hippocampal potentiation in the rat.
Topics: Amygdala; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Kindling, Neurologic; Long-Term Potentiation; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1999 |
The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP+.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Kynurenic Acid; Microinjections; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1999 |
Hippocampal theta rhythm in anesthetized rats: role of AMPA glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Electroencephalography; Hippocampus; Male; Physostigmine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Septum Pellucidum; Theta Rhythm | 1999 |
Serotonin depolarizes hippocampal interneurones in the rat stratum oriens by interaction with 5HT2 receptors.
Topics: Animals; Hippocampus; In Vitro Techniques; Indophenol; Interneurons; Male; Membrane Potentials; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin | 1999 |
Ionotropic glutamate receptor modulation of 5-HT6 and 5-HT7 mRNA expression in rat brain.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Serotonin; RNA, Messenger; Schizophrenia | 1999 |
Effects of the AMPA receptor antagonist NBQX on outcome of newborn pigs after asphyxic cardiac arrest.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Pressure; Brain; Brain Stem; Carbon Dioxide; Cardiopulmonary Resuscitation; Consciousness; Electron Transport Complex IV; Epinephrine; Excitatory Amino Acid Antagonists; Heart Arrest; Humans; Infant, Newborn; Neurons; Oxygen; Partial Pressure; Purkinje Cells; Quinoxalines; Receptors, AMPA; Seizures; Swine | 1999 |
Beta-amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Neocortex; Neurons; Peptide Fragments; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1999 |
Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in the control of prolactin, growth hormone and gonadotropin secretion in prepubertal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Domperidone; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Growth Hormone; Kainic Acid; Luteinizing Hormone; Male; Ovariectomy; Pituitary Gland, Anterior; Prolactin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine; Sexual Maturation | 1999 |
Expression of cyclooxygenase-2 mRNA after global ischemia is regulated by AMPA receptors and glucocorticoids.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cyclooxygenase 2; Dexamethasone; Excitatory Amino Acid Antagonists; Glucocorticoids; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Time Factors; Tissue Distribution | 1999 |
Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-D-aspartate receptors and glucocorticoids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cortical Spreading Depression; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Disease Susceptibility; Dizocilpine Maleate; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Indomethacin; Isoenzymes; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Parietal Lobe; Phospholipases A; Phospholipases A2; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcriptional Activation | 1999 |
On the synchronizing mechanisms of tetanically induced hippocampal oscillations.
Topics: Action Potentials; Animals; Bicuculline; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Models, Neurological; Oscillometry; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Synapses; Synaptic Transmission | 1999 |
Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; GluK2 Kainate Receptor; Glutamates; Hippocampus; Humans; Isoquinolines; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Tetrazoles | 1999 |
Memory impairment after soman intoxication in rat: correlation with central neuropathology. Improvement with anticholinergic and antiglutamatergic therapeutics.
Topics: Animals; Antidotes; Atropine; Behavior, Animal; Cholinergic Antagonists; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Soman; Spatial Behavior; Survival Rate; Time Factors | 1999 |
Selective glutamate receptor antagonists can induce or prevent axonal sprouting in rat hippocampal slice cultures.
Topics: Animals; Axons; Culture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GAP-43 Protein; Glial Fibrillary Acidic Protein; Hippocampus; Nerve Regeneration; Piperazines; Quinoxalines; Rats; Rats, Wistar | 1999 |
The role of non-N-methyl-D-aspartate ionotropic glutamate receptors in the spinal transmission of nociception in normal animals and animals with carrageenan inflammation.
Topics: Animals; Carrageenan; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoquinolines; Male; Neuritis; Nociceptors; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 1999 |
Do nuclear condensation or fragmentation and DNA fragmentation reflect the mode of neuronal death?
Topics: Animals; Cell Death; Cerebellum; Colchicine; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Glucose; In Situ Nick-End Labeling; Microscopy, Confocal; Neurons; Oxygen; Quinoxalines; Rats; Rats, Wistar | 1999 |
Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Isoxazoles; Molecular Conformation; Oocytes; Propionates; Quinoxalines; Radioligand Assay; Rats; Receptors, AMPA; Recombinant Fusion Proteins; Stereoisomerism; Tritium; Xenopus | 1999 |
Role of glutamate receptors in transmission of vagal cardiac input to neurones in the nucleus tractus solitarii in dogs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dogs; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart; In Vitro Techniques; Microelectrodes; N-Methylaspartate; Neurons; Neurons, Afferent; Quinoxalines; Receptors, Glutamate; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 1999 |
Neurotrophic effect of isoquinoline derivatives in primary cortical culture.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Flunarizine; Isoquinolines; Mice; Nerve Growth Factors; Neurons; Nicardipine; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Multiple and opposing roles of cholinergic transmission in the main olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Calcium; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Kinetics; Magnesium; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Receptors, GABA-A; Receptors, Nicotinic; Synapses | 1999 |
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antioxidants; Cell Membrane Permeability; Chlorides; Chromans; Deferoxamine; Extracellular Space; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Microscopy, Confocal; Muscimol; Nipecotic Acids; Oxidative Stress; Pyramidal Cells; Quinolinium Compounds; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tiagabine | 1999 |
Excitotoxic effects of non-NMDA receptor agonists in organotypic corticostriatal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; L-Lactate Dehydrogenase; Neocortex; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar | 1999 |
Double-tracer autoradiographic study of protein synthesis and glucose consumption in rats with focal cerebral ischemia.
Topics: Animals; Autoradiography; Blood Pressure; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Ischemic Attack, Transient; Leucine; Male; Nerve Tissue Proteins; Quinoxalines; Radioisotope Dilution Technique; Rats; Rats, Wistar; Reference Values; Tritium | 1999 |
Androgens modulate NMDA receptor-mediated EPSCs in the zebra finch song system.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androgens; Animals; Brain; Dendrites; Dihydrotestosterone; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Songbirds; Synaptic Transmission; Testosterone; Vocalization, Animal | 1999 |
Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Homocysteine; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1999 |
Medullary lateral tegmental field: an important synaptic relay in the baroreceptor reflex pathway of the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baroreflex; Brain Mapping; Cats; Excitatory Amino Acid Antagonists; Heart Conduction System; Medulla Oblongata; Microinjections; Quinoxalines; Solitary Nucleus; Sympathetic Nervous System; Synapses; Tegmentum Mesencephali | 1999 |
Carbachol-induced changes in excitability and [Ca2+]i signalling in projection cells of medial entorhinal cortex layers II and III.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists; Electrophysiology; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Organ Culture Techniques; Periodicity; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin | 1999 |
1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Bridged Bicyclo Compounds; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Indans; Ischemic Attack, Transient; Mice; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
The neuroprotective and hypothermic effect of GYKI-52466, a non-competitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-antagonist on histological and behavioural variables in the gerbil global ischemia model.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Body Temperature; Chlorpromazine; Excitatory Amino Acid Antagonists; Gerbillinae; Ischemic Attack, Transient; Male; Maze Learning; Motor Activity; Neuroprotective Agents; Quinoxalines; Receptors, AMPA; Time Factors | 1999 |
Effects of ionotropic glutamate receptor blockade and 5-HT1A receptor activation on spreading depression in rat neocortical slices.
Topics: Animals; Cortical Spreading Depression; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketamine; Neocortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists | 1999 |
Late embryonic expression of AMPA receptor function in the CA1 region of the intact hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Aging; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Cations, Divalent; Electric Stimulation; Embryonic and Fetal Development; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Hypoxia; Lysine; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Tetrodotoxin | 1999 |
AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward.
Topics: Amygdala; Animals; Choice Behavior; Conditioning, Operant; Dextroamphetamine; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; Neurons; Nucleus Accumbens; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, AMPA; Reward | 1999 |
NMDA and AMPA glutamate receptor subtypes in the thoracic spinal cord in lean and obese-diabetic ob/ob mice.
Topics: Animals; Autoradiography; Dizocilpine Maleate; Female; Kinetics; Male; Mice; Mice, Obese; Neurons; Obesity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Spinal Cord; Thinness; Tritium | 1999 |
Nitric oxide is the predominant mediator of cerebellar hyperemia during somatosensory activation in rats.
Topics: Animals; Blood Pressure; Brain Stem; Carbon Dioxide; Cerebellar Cortex; Cerebellum; Cerebrovascular Circulation; Electric Stimulation; Enzyme Inhibitors; Glucose; Hyperemia; Indazoles; Laser-Doppler Flowmetry; Male; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Somatosensory Cortex; Tetrodotoxin | 1999 |
Long-term effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione in the rat basal ganglia: calcification, changes in glutamate receptors and glial reactions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Autoradiography; Basal Ganglia; Brain Chemistry; Calcinosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Isradipine; Male; Microglia; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nimodipine; Picolinic Acids; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Neurons; Multiple Sclerosis; Muscle Tonus; Myelin Basic Protein; Neurons; Organophosphonates; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; Receptors, Kainic Acid; Recurrence; Spinal Cord; T-Lymphocytes | 2000 |
Glutamate excitotoxicity in a model of multiple sclerosis.
Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Multiple Sclerosis; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; T-Lymphocytes | 2000 |
Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid.
Topics: Animals; Apoptosis; Caspases; Corpus Striatum; Decerebrate State; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mitochondria; Nervous System; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Superoxides | 2000 |
Effects of AMPA/kainate glutamate receptor antagonists on cocaine-induced convulsions and lethality in mice.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Mice; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 1999 |
Developmental changes in the neurotransmitter regulation of correlated spontaneous retinal activity.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cholinergic Fibers; Excitatory Amino Acid Antagonists; Ferrets; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Interneurons; Periodicity; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Synaptic Transmission; Vision, Ocular; Visual Pathways | 2000 |
Disruption of operant oral self-administration of ethanol, sucrose, and saccharin by the AMPA/kainate antagonist, NBQX, but not the AMPA antagonist, GYKI 52466.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Male; Motor Activity; Quinoxalines; Rats; Receptors, AMPA; Saccharin; Self Administration; Sucrose; Sweetening Agents | 1999 |
Synaptic GABA(A) activation inhibits AMPA-kainate receptor-mediated bursting in the newborn (P0-P2) rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Hippocampus; In Vitro Techniques; Interneurons; Muscimol; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Synapses | 2000 |
Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Cerebellar Nuclei; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Microelectrodes; Neurons; Picrotoxin; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2000 |
Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Chromans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Fluoresceins; Fluorescent Dyes; Iodoacetates; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Choline O-Acetyltransferase; Corpus Striatum; Electrophysiology; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Antagonists; In Situ Hybridization; Indoles; Interneurons; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurokinin A; Oligopeptides; omega-N-Methylarginine; Peptide Fragments; Phenanthridines; Phosphodiesterase Inhibitors; Piperidines; Pyrrolidinones; Quinoxalines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; RNA, Messenger; Signal Transduction; Substance P; Tachykinins; Tetrodotoxin; Tritium | 2000 |
Field potential analysis of synaptic transmission in spiking neurons in a sparse and irregular neuronal structure in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Brain Stem; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Intracellular Membranes; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synaptic Transmission | 2000 |
Non-N-methyl-D-aspartate (NMDA) receptor antagonist 1,2,3, 4-tetrahydro-6-nitro-2,3-dioxo-benzo(f)quinoxaline-7-sulphonamide (NBQX) decreases functional disorders in cytotoxic brain oedema.
Topics: Animals; Behavior, Animal; Brain; Brain Edema; Excitatory Amino Acid Antagonists; Hexachlorophene; Male; Motor Activity; Motor Skills Disorders; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
AMPA glutamate receptors and respiratory control in the developing rat: anatomic and pharmacological aspects.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Excitatory Amino Acid Antagonists; Hypercapnia; Hypoxia; Immunohistochemistry; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; Respiration; Respiratory Physiological Phenomena; Solitary Nucleus | 2000 |
Vasopressin increases GABAergic inhibition of rat hypothalamic paraventricular nucleus neurons in vitro.
Topics: Action Potentials; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Neural Inhibition; Oxytocin; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Long-Evans; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin; Vasoconstrictor Agents; Vasopressins | 2000 |
Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Denervation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Neuronal Plasticity; Patch-Clamp Techniques; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Spinal Nerve Roots; Synapses | 2000 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Functional GluR6 kainate receptors in the striatum: indirect downregulation of synaptic transmission.
Topics: Animals; Benzodiazepines; Corpus Striatum; Down-Regulation; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; GluK2 Kainate Receptor; Kainic Acid; Mice; Mice, Inbred C57BL; Neuromuscular Depolarizing Agents; Neurons; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Kainic Acid; RNA, Messenger; Synaptic Transmission | 2000 |
NMDA and AMPA receptors in the dorsal nucleus of the lateral lemniscus shape binaural responses in rat inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Cochlear Nucleus; Excitatory Amino Acid Antagonists; Functional Laterality; Hearing; In Vitro Techniques; Inferior Colliculi; Male; Piperazines; Pons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors | 2000 |
Isoflurane and pentobarbital reduce AMPA toxicity in vivo in the rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Blood Pressure; Cerebral Cortex; Cerebral Infarction; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Modulators; Heart Rate; Image Processing, Computer-Assisted; Isoflurane; Necrosis; Pentobarbital; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, AMPA | 2000 |
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine | 2000 |
Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Conserved Sequence; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Kainic Acid; Kidney; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Mutagenesis; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Receptors, Glutamate; Transfection | 2000 |
Developmental regulation of AMPA-receptor properties in CA1 pyramidal neurons of rat hippocampus.
Topics: Alternative Splicing; Animals; Animals, Newborn; Benzodiazepines; Benzothiadiazines; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Kinetics; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid | 2000 |
Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Isoxazoles; N-Methylaspartate; Propionates; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Medullary lateral tegmental field: an important source of basal sympathetic nerve discharge in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baroreflex; Blood Pressure; Cats; Excitatory Amino Acid Antagonists; Medulla Oblongata; Membrane Potentials; Microinjections; Neurons; Pressoreceptors; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathectomy; Sympathetic Nervous System; Synaptic Transmission; Tegmentum Mesencephali | 2000 |
Action of locally administered NMDA and AMPA/kainate receptor antagonists in spinal cord injury.
Topics: Animals; Cerebellum; Dizocilpine Maleate; Evoked Potentials; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries | 2000 |
Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus.
Topics: Action Potentials; Animals; Calibration; Excitatory Postsynaptic Potentials; Extracellular Space; Guinea Pigs; Hippocampus; In Vitro Techniques; Microelectrodes; Neurons; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, Presynaptic; Synapses; Valine | 2000 |
Electrical responses in hippocampal slices after prolonged global ischemia: effects of neuroprotectors.
Topics: Action Potentials; Animals; Brain Ischemia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2000 |
Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neural Inhibition; Propionates; Quinoxalines; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission | 2000 |
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cerebellum; D-Amino-Acid Oxidase; Embryo, Mammalian; Glycine; Hippocampus; In Vitro Techniques; Ligands; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 2000 |
Ionotropic glutamate receptor-mediated responses in the rat primary somatosensory cortex evoked by noxious and innocuous cutaneous stimulation in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Male; N-Methylaspartate; Neurons; Pain; Piperazines; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Skin; Somatosensory Cortex; Synapses; Time Factors | 2000 |
Impulsivity and AMPA receptors: aniracetam ameliorates impulsive behavior induced by a blockade of AMPA receptors in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Impulsive Behavior; Male; Motor Activity; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 2000 |
Laminar characteristics of functional connectivity in rat barrel cortex revealed by stimulation with caged-glutamate.
Topics: Animals; Brain Mapping; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neural Pathways; Neurons; Photic Stimulation; Photolysis; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Somatosensory Cortex; Synapses; Time Factors; Valine; Vibrissae | 2000 |
Short-term potentiation of miniature excitatory synaptic currents causes excitation of supraoptic neurons.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Male; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus; Synaptic Transmission; Tetrodotoxin | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Blocking the trigeminal EPSP in rat abducens motoneurons in vivo with the AMPA antagonists NBQX and GYKI 53655.
Topics: Abducens Nerve; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Trigeminal Nerve | 2000 |
Superoxide dismutase activity and the effects of NBQX and CPP on lipid peroxidation in experimental spinal cord injury.
Topics: Animals; Excitatory Amino Acid Antagonists; Lipid Peroxidation; Male; Malondialdehyde; N-Methylaspartate; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase | 2000 |
Non-NMDA receptor-mediated mechanisms are involved in levodopa-induced motor response alterations in Parkinsonian rats.
Topics: Animals; Antiparkinson Agents; Dextromethorphan; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Parkinsonian Disorders; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Riluzole; Rotation | 2000 |
4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives: highly potent and selective AMPA receptors antagonists with in vivo activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Isoquinolines; Mice; Mice, Inbred DBA; Pyrazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tetrazoles; Urea | 2000 |
Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dicarboxylic Acids; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2000 |
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia.
Topics: Animals; Brain Ischemia; Carotid Stenosis; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Hippocampus; In Situ Nick-End Labeling; Isoquinolines; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Tetrazoles | 2000 |
[Excitatory amino acid antagonists and potentiation of cortical evoked potentials].
Topics: Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Male; Quinoxalines; Rats; Receptors, AMPA | 1999 |
Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amines; Animals; Aspartic Acid; Calcium; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Male; Neostriatum; Neurons; Neurotransmitter Agents; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synaptosomes; Tritium | 2000 |
Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chick Embryo; Dendrites; Excitatory Amino Acid Antagonists; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Retina; Retinal Ganglion Cells; rho GTP-Binding Proteins; Synaptic Transmission; Tetrodotoxin; Transfection | 2000 |
Calcium influx through NMDA receptors directly evokes GABA release in olfactory bulb granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Calcium; Calcium Channels; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 2000 |
Inhibition of different pathways influencing Na(+) homeostasis protects organotypic hippocampal slice cultures from hypoxic/hypoglycemic injury.
Topics: Animals; Brain Ischemia; Cell Death; Culture Techniques; Dizocilpine Maleate; Electrophysiology; Hippocampus; Homeostasis; Hypoglycemia; Hypoxia; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Tetrodotoxin; Thiourea | 2000 |
Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1.
Topics: 2-Amino-5-phosphonovalerate; Adult; Barium Compounds; Bicuculline; Buffers; Chlorides; Electric Stimulation; Electrophysiology; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Humans; In Vitro Techniques; Potassium; Quinoxalines; Sclerosis; Synaptic Transmission | 2000 |
Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Image Processing, Computer-Assisted; Membrane Potentials; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Patch-Clamp Techniques; Picrotoxin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Sodium; Synapses; Synaptic Transmission; Tetrodotoxin | 2000 |
Functional role of NMDA autoreceptors in olfactory mitral cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoreceptors; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Nifedipine; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2000 |
Excitatory cortical inputs to pallidal neurons via the subthalamic nucleus in the monkey.
Topics: Animals; Bicuculline; Brain Mapping; Cerebral Cortex; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; Globus Pallidus; Macaca; Membrane Potentials; Microinjections; Muscimol; Neural Pathways; Neurons; Piperazines; Quinoxalines; Reaction Time; Subthalamic Nucleus | 2000 |
Effects of riluzole on electrically evoked neurotransmitter release.
Topics: Acetylcholine; Animals; Calcium; Dicarboxylic Acids; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Mice; Neostriatum; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Riluzole; Serotonin; Tetrodotoxin; Tritium | 2000 |
Effect of pretreatment with intrathecal excitatory amino acid receptor antagonists on the development of pain behavior caused by plantar incision.
Topics: Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Foot; Halothane; Injections, Spinal; Male; Motor Activity; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley | 2000 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium | 2000 |
White matter injury in spinal cord ischemia: protection by AMPA/kainate glutamate receptor antagonism.
Topics: Animals; Anterior Horn Cells; Axons; Behavior, Animal; Cell Count; Excitatory Amino Acid Antagonists; Hindlimb; Injections, Spinal; Male; Motor Activity; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Recovery of Function; Spinal Cord Ischemia | 2000 |
Relative magnitude of tonic and phasic synaptic excitation of medullary inspiratory neurons in dogs.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Male; Medulla Oblongata; Neurons; Picrotoxin; Quinoxalines; Respiratory Physiological Phenomena; Strychnine; Synapses | 2000 |
Studies of aminochrome toxicity in a mouse derived neuronal cell line: is this toxicity mediated via glutamate transmission?
Topics: Animals; Catalase; Cell Line; Cell Survival; Cerebral Cortex; Dicumarol; Dopamine; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Indolequinones; Indoles; Mice; Models, Biological; NAD; NAD(P)H Dehydrogenase (Quinone); Neurons; Oxidation-Reduction; Quinoxalines; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Uncoupling Agents | 2000 |
A high GluR1 : GluR2 expression ratio is correlated with expression of Ca2+-binding proteins in rat forebrain neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Biological Transport; Calbindin 1; Calbindins; Calcium; Calcium Channel Blockers; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; In Situ Hybridization; Neurons; Parvalbumins; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; S100 Calcium Binding Protein G | 2000 |
AMPA receptor antagonists, GYKI 52466 and NBQX, do not block the induction of long-term potentiation at therapeutically relevant concentrations.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Memory; Neurodegenerative Diseases; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2000 |
Regulation of prolactin secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Depression, Chemical; Dizocilpine Maleate; Male; Pituitary Gland; Prolactin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sexual Maturation | 2000 |
Glutamatergic drugs exacerbate symptomatic behavior in a transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder.
Topics: Animals; Cerebral Cortex; Comorbidity; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Limbic System; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Seizures; Tourette Syndrome | 2000 |
Concentration-dependent substate behavior of native AMPA receptors.
Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Ion Channels; Kainic Acid; Mice; Mice, Inbred C57BL; Neuromuscular Depolarizing Agents; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Membranes | 2000 |
Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures.
Topics: Animals; Biomarkers; Corpus Striatum; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hippocampus; Models, Biological; Organ Culture Techniques; Propidium; Quinoxalines; Rats; Receptors, Glutamate | 2000 |
Laminar differences in recurrent excitatory transmission in the rat entorhinal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lysine; Male; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2000 |
Expression and conditioned inhibition of fear-potentiated startle after stimulation and blockade of AMPA/Kainate and GABA(A) receptors in the dorsal periaqueductal gray.
Topics: Acoustic Stimulation; Animals; Conditioning, Classical; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fear; Kainic Acid; Light; Male; Microinjections; Periaqueductal Gray; Picrotoxin; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Reflex, Startle | 2000 |
Cortical death caused by striatal administration of AMPA and interleukin-1 is mediated by activation of cortical NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cerebral Cortex; Corpus Striatum; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Interleukin-1; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Role of the calcium-binding protein parvalbumin in short-term synaptic plasticity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Egtazic Acid; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; In Vitro Techniques; Interneurons; Mice; Mice, Knockout; Neuronal Plasticity; Parvalbumins; Purkinje Cells; Quinoxalines; Synapses | 2000 |
Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons.
Topics: Animals; Apoptosis; Bilirubin; Caspases; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Indoles; Male; Neurons; Oligopeptides; Pregnancy; Prosencephalon; Protein Kinase C; Protein Synthesis Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thymidine; Tritium | 2000 |
NBQX attenuates excitotoxic injury in developing white matter.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Male; Microinjections; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate | 2000 |
NMDA and AMPA/kainate glutamate receptors modulate dentate neurogenesis and CA3 synapsin-I in normal and ischemic hippocampus.
Topics: Animals; Brain Ischemia; Cell Division; Dentate Gyrus; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Gerbillinae; Glutamic Acid; Male; Memory; Microinjections; Neurons; Neuroprotective Agents; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapsins | 2000 |
Inflammation contributes to the postponed ischemic neuronal damage following treatment with a glutamate antagonist in rats.
Topics: Animals; Anti-Bacterial Agents; Doxycycline; Encephalitis; Excitatory Amino Acid Antagonists; Ischemic Attack, Transient; Male; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Rolipram | 2001 |
Magnesium deprivation decreases cellular reduced glutathione and causes oxidative neuronal death in murine cortical cultures.
Topics: Animals; Cell Death; Cerebral Cortex; Coculture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Glutathione; Lipid Peroxidation; Magnesium; Mice; Neuroglia; Neurons; Neurotoxins; Oxidative Stress; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis?
Topics: Animals; Axons; Cell Death; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutaminase; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelitis; Neuroprotective Agents; Neurotoxins; Oligodendroglia; Quinoxalines; Receptors, AMPA | 2000 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium | 2001 |
A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Neuronal Plasticity; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synapsins; Synaptic Transmission; Synaptic Vesicles; Tetanus Toxin | 2001 |
Distinct effect of pregnenolone sulfate on NMDA receptor subtypes.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Line; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperazines; Pregnenolone; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 2001 |
Changing specificity of neurotransmitter regulation of rapid dendritic remodeling during synaptogenesis.
Topics: Acetylcholine; Animals; Bacterial Proteins; Cell Movement; Chick Embryo; Dendrites; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Luminescent Proteins; Microscopy, Confocal; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Transfection | 2001 |
Extension of glial processes by activation of Ca2+-permeable AMPA receptor channels.
Topics: Adenoviridae; Animals; Calcium; Cell Size; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Neuroglia; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 2001 |
Enhanced NMDA receptor activity in retinal inputs to the rat suprachiasmatic nucleus during the subjective night.
Topics: Animals; Biological Clocks; Circadian Rhythm; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Light; Male; N-Methylaspartate; Neurons; Optic Chiasm; Optic Nerve; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 2001 |
The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures.
Topics: Animals; Coloring Agents; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Propidium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Staining and Labeling | 2001 |
Kindling induces transient fast inhibition in the dentate gyrus--CA3 projection.
Topics: 2-Amino-5-phosphonovalerate; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Kindling, Neurologic; Mossy Fibers, Hippocampal; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time | 2001 |
Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Carrier Proteins; Cell Line; Cerebellum; Cerebral Cortex; Dogs; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Excitatory Amino Acid Transporter 4; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Kidney; Kinetics; Neurotransmitter Uptake Inhibitors; Oocytes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Symporters; Synaptosomes; Xenopus laevis | 2001 |
Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses.
Topics: Animals; Dentate Gyrus; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Long-Term Potentiation; Mossy Fibers, Hippocampal; Pyramidal Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 2001 |
Effects of cerestat and NBQX on functional and morphological outcomes in rat focal cerebral ischemia.
Topics: Animals; Behavior, Animal; Brain; Cerebral Infarction; Excitatory Amino Acid Antagonists; Forelimb; Guanidines; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Neuroprotective Agents; Physical Stimulation; Proprioception; Psychomotor Performance; Quinoxalines; Rats; Rats, Inbred F344; Vibrissae | 2001 |
Enhanced temporal stability of cholinergic hippocampal gamma oscillations following respiratory alkalosis in vitro.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis, Respiratory; Animals; Carbachol; Carbon Dioxide; Cholinergic Fibers; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Hippocampus; Hydrogen-Ion Concentration; Lidocaine; Male; Methylamines; Midazolam; Nerve Tissue Proteins; Pentobarbital; Periodicity; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Time Factors | 2001 |
Kindling induces transient NMDA receptor-mediated facilitation of high-frequency input in the rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Dentate Gyrus; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Ion Channel Gating; Kindling, Neurologic; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Patch-Clamp Techniques; Perforant Pathway; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Reliability of monosynaptic sensory transmission in brain stem neurons in vitro.
Topics: Action Potentials; Afferent Pathways; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Reproducibility of Results; Solitary Nucleus; Synaptic Transmission; Time Factors; Vagus Nerve | 2001 |
Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidaz.
Topics: Animals; Anticonvulsants; Carboxylic Acids; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Injections, Intravenous; Isoquinolines; Mice; Pyrazines; Quinoxalines; Rats; Receptors, AMPA; Structure-Activity Relationship; Tetrazoles; Xenopus | 2001 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2001 |
Characterization of spontaneous excitatory synaptic currents in pyramidal cells of rat prelimbic cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 2001 |
Dynamic modulation of excitation and inhibition during stimulation at gamma and beta frequencies in the CA1 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Male; Neural Inhibition; Periodicity; Phosphinic Acids; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley | 2001 |
A kainate receptor increases the efficacy of GABAergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Benzodiazepines; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neurons; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Staurosporine; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2001 |
A metabotropic glutamate receptor antagonist, alpha-methyl-4-carboxyphenylglycine, attenuates immediate early gene mRNA expression following traumatic injury in cultured rat cortical glial cells.
Topics: Animals; Benzoates; Brain Injuries; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation; Genes, Immediate-Early; Gliosis; Glycine; Nerve Regeneration; Neuroglia; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcriptional Activation | 2001 |
Ampa/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter.
Topics: Action Potentials; Animals; Anti-Anxiety Agents; Axons; Benzodiazepines; Calcium; Cell Death; Cell Hypoxia; Corpus Callosum; Excitatory Amino Acid Antagonists; Female; Glucose; Hypoxia, Brain; In Vitro Techniques; Mice; Models, Biological; Nerve Fibers, Myelinated; Oligodendroglia; Oxygen; Propidium; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers | 2001 |
Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors.
Topics: Allosteric Site; Animals; Benzamides; Benzodiazepines; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides; Tritium | 2001 |
The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury.
Topics: Animals; Behavior, Animal; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Grooming; Indans; Male; Nerve Degeneration; Neurons; Neurotoxins; Opioid Peptides; Pain; Pain Measurement; Protein Precursors; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; RNA, Messenger; Spinal Cord; Spinal Cord Injuries | 2001 |
In vivo pharmacology of BIIR 561 CL, a novel combined antagonist of AMPA receptors and voltage-dependent Na(+) channels.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Death; Dose-Response Relationship, Drug; Electric Stimulation; Female; Lethal Dose 50; Male; Mexiletine; Mice; Neuroprotective Agents; Oxadiazoles; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, AMPA; Sodium Channel Blockers | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Multiple rostral medullary nuclei can influence breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Electromyography; Excitatory Amino Acid Antagonists; Female; Goats; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Orchiectomy; Oxygen Consumption; Quinoxalines; Respiratory Mechanics; Respiratory Muscles; Tidal Volume; Vestibular Nuclei | 2001 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Kidney; Lactic Acid; Maternal Behavior; Microdialysis; Pyruvic Acid; Quinoxalines; Rats; Receptors, Glutamate; Survival Rate; Treatment Outcome | 2001 |
AMPA and NMDA receptors regulate responses of neurons in the rat's inferior colliculus.
Topics: Acoustic Stimulation; Action Potentials; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Inferior Colliculi; Male; Neurons; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
The AMPA receptor/Na(+) channel blocker BIIR 561 CL is protective in a model of global cerebral ischaemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Male; Neuroprotective Agents; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Channel Blockers; Survival Rate | 2001 |
Presynaptic modulation by group III metabotropic glutamate receptors (mGluRs) of the excitatory postsynaptic potential mediated by mGluR1 in rat cerebellar Purkinje cells.
Topics: Animals; Benzoates; Bicuculline; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Male; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Presynaptic | 2001 |
Involvement of non-NMDA receptors in the rescue of weaver cerebellar granule neurons and sensitivity to ethanol of cerebellar AMPA receptors in oocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Ethanol; Excitatory Amino Acid Antagonists; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Expression; Immunoblotting; Membrane Potentials; Mice; Mice, Neurologic Mutants; Neurons; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xenopus | 2001 |
Electrophysiological evidence for vasopressin V(1) receptors on neonatal motoneurons, premotor and other ventral horn neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Anterior Horn Cells; Arginine Vasopressin; Bicuculline; Deamino Arginine Vasopressin; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Glycine Agents; Hemosiderin; Hormone Antagonists; Interneurons; Male; Oxytocin; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Strychnine; Vasotocin | 2001 |
GABA(B) and NMDA receptors contribute to spindle-like oscillations in rat thalamus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Female; Fourier Analysis; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Magnesium; Male; Membrane Potentials; Organ Culture Techniques; Organophosphorus Compounds; Pentobarbital; Periodicity; Picrotoxin; Quinoxalines; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Species Specificity; Thalamus | 2001 |
Glutamate receptors form hot spots on apical dendrites of neocortical pyramidal neurons.
Topics: Action Potentials; Animals; Cadmium; Calcium; Dendrites; Excitatory Amino Acid Antagonists; Male; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium; Tetrodotoxin | 2001 |
Glomerulus-specific synchronization of mitral cells in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Periodicity; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell | 2001 |
Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cadmium; Calcium; Calcium Channels; Calcium Signaling; Cesium; Dendrites; Egtazic Acid; Glutamates; Hippocampus; Light; Organ Culture Techniques; Patch-Clamp Techniques; Photolysis; Pyramidal Cells; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
Imaging postsynaptic activities of teleost thalamic neurons at single cell resolution using a voltage-sensitive dye.
Topics: Animals; Dendrites; Electronic Data Processing; Excitatory Amino Acid Antagonists; Fishes; Fluorescent Dyes; Image Processing, Computer-Assisted; Membrane Potentials; Pyridinium Compounds; Quinoxalines; Receptors, AMPA; Synaptic Membranes; Thalamus | 2001 |
Evidence for a role for GABA(A) and NMDA receptors in ethanol inhibition of long-term potentiation.
Topics: Animals; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Long-Term Potentiation; Male; Memory; Organ Culture Techniques; Organophosphorus Compounds; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Electrophysiology of interneurons in the glomerular layer of the rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthetics, Local; Animals; Cell Size; Choline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Interneurons; Lidocaine; Male; Nickel; Nootropic Agents; Olfactory Bulb; Patch-Clamp Techniques; Periodicity; Quinoxalines; Rats; Rats, Sprague-Dawley | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
TNF-alpha-induced c-Fos generation in the nucleus of the solitary tract is blocked by NBQX and MK-801.
Topics: Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Microinjections; Neurons; Oxytocin; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Solitary Nucleus; Tumor Necrosis Factor-alpha | 2001 |
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Animals; Atropine; Cerebral Cortex; Cobalt; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamates; Kynurenic Acid; Male; Muscarinic Antagonists; Neurons; Neurotransmitter Agents; Phentolamine; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Thalamus; Vagus Nerve; Viscera | 2001 |
Multivesicular release at climbing fiber-Purkinje cell synapses.
Topics: Animals; Biological Transport; Calcium; Dipeptides; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Kynurenic Acid; Neurotransmitter Agents; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Synapses; Synaptic Transmission | 2001 |
Glutaminergic vagal afferents may mediate both retching and gastric adaptive relaxation in dogs.
Topics: Action Potentials; Animals; Catheterization; Dizocilpine Maleate; Dogs; Esophagus; Excitatory Amino Acid Antagonists; Ganglionic Blockers; Glutamic Acid; Hexamethonium; Neurons, Afferent; Quinoxalines; Reflex; Solitary Nucleus; Stomach; Vagotomy; Vagus Nerve; Vomiting | 2001 |
The expression of cerebellar LTD in culture is not associated with changes in AMPA-receptor kinetics, agonist affinity, or unitary conductance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Mice; Phorbol Esters; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.
Topics: Animals; Brain Mapping; Critical Period, Psychological; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses; Thalamus | 2001 |
Inactivity produces increases in neurotransmitter release and synapse size.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Homeostasis; Microscopy, Electron; Neurons; Neurotransmitter Agents; Quinoxalines; Rats; Synaptic Transmission; Synaptic Vesicles | 2001 |
NMDA receptor-dependent periodic oscillations in cultured spinal cord networks.
Topics: Animals; Bicuculline; Cells, Cultured; Electrophysiology; GABA Antagonists; Glycine Agents; Membrane Potentials; Mice; Mice, Inbred ICR; Microelectrodes; Nerve Net; Neurotransmitter Agents; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine | 2001 |
Chronic exposure of kainate and NBQX changes AMPA toxicity in hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Death; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar | 2001 |
Visual pathways involved in fear conditioning measured with fear-potentiated startle: behavioral and anatomic studies.
Topics: Amygdala; Animals; Behavior, Animal; Biotin; Conditioning, Classical; Dextrans; Electroshock; Excitatory Amino Acid Antagonists; Fear; Male; Odorants; Photic Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex, Startle; Smell; Stimulation, Chemical; Thalamic Nuclei; Thalamus; Visual Pathways | 2001 |
Involvement of spinal N-methyl-D-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nerve Fibers; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P; Synapses; Synaptic Transmission | 2001 |
Differential effects of an NMDA and a non-NMDA receptor antagonist on medullary lateral tegmental field neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Antagonists; Heart Rate; Iontophoresis; Medulla Oblongata; Neurons; Pressoreceptors; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System; Tegmentum Mesencephali | 2002 |
Behavioral analysis of anorexia produced by hindbrain injections of AMPA receptor antagonist NBQX in rats.
Topics: Animals; Anorexia; Avoidance Learning; Behavior, Animal; Dietary Sucrose; Drinking; Eating; Excitatory Amino Acid Antagonists; Feeding Behavior; Fourth Ventricle; Glutamic Acid; Injections, Intraventricular; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Satiation; Solitary Nucleus; Taste | 2002 |
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.
Topics: Animals; Azo Compounds; Coloring Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extremities; Glutamic Acid; Glutamine; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroarginine; Nociceptors; Penicillamine; Quinoxalines; Trypan Blue | 2002 |
Long-lasting synaptic modification in the rat hippocampus resulting from NMDA receptor blockade during development.
Topics: Animals; Behavior, Animal; Cell Differentiation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Long-Term Potentiation; Neuronal Plasticity; Neurons; Organ Culture Techniques; Piperazines; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2002 |
Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics, Local; Animals; Barium; Buffers; Diuretics; Enzyme Inhibitors; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Furosemide; Hippocampus; Humans; In Vitro Techniques; Iontophoresis; Ouabain; Potassium; Quaternary Ammonium Compounds; Quinoxalines; Rats; Rats, Wistar; Sclerosis; Tetrodotoxin | 2002 |
Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity.
Topics: Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Carbazoles; Cerebral Cortex; Clonidine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Models, Neurological; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phenazocine; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Scopolamine | 2002 |
Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoblotting; Male; Middle Aged; Neocortex; Neurons; Norepinephrine; omega-Agatoxin IVA; Potassium; Pregabalin; Quinoxalines; Receptors, AMPA; Synaptosomes | 2002 |
Altered glutamate receptor function during recovery of bladder detrusor-external urethral sphincter coordination in a rat model of spinal cord injury.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Hindlimb; Injections, Spinal; Muscle Contraction; Muscle, Smooth; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Urethra; Urinary Bladder; Urodynamics | 2002 |
Correlation of the expression of kainate receptor subtypes to responses evoked in cultured cortical and spinal cord neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Concanavalin A; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2002 |
The non-NMDA receptor antagonist NBQX does not affect rats performance in the object recognition task.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Motor Activity; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA | 2002 |
Fast network oscillations in the rat dentate gyrus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Bicuculline; Dentate Gyrus; Excitatory Amino Acid Antagonists; GABA Antagonists; Membrane Potentials; Organ Culture Techniques; Periodicity; Phosphinic Acids; Potassium; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 2002 |
The life cycle of Ca(2+) ions in dendritic spines.
Topics: Action Potentials; Animals; Bicuculline; Buffers; Calcium; Cells, Cultured; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; Hippocampus; In Vitro Techniques; Mathematics; Microscopy, Confocal; Models, Neurological; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2002 |
Role of spinal NMDA and non-NMDA receptors in the pressor reflex response to abdominal ischemia.
Topics: 2-Amino-5-phosphonovalerate; Abdomen; Animals; Baroreflex; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Female; Ischemia; Male; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive oxygen species.
Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Chlorodiphenyl (54% Chlorine); Cyclosporine; Cytoplasmic Granules; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Nitric oxide facilitates GABAergic neurotransmission in the cat oculomotor system: a physiological mechanism in eye movement control.
Topics: Abducens Nerve; Animals; Bicuculline; Brain Stem; Cats; Excitatory Amino Acid Antagonists; Eye Movements; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine Agents; Nitric Oxide; Nitric Oxide Synthase; Oculomotor Nerve; Quinoxalines; Reflex, Vestibulo-Ocular; Strychnine; Synaptic Transmission | 2002 |
GABAergic and glutamatergic modulation of spontaneous and motor-cortex-evoked complex spike activity.
Topics: Action Potentials; Animals; Central Nervous System Stimulants; Cerebellum; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Motor Cortex; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Olivary Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Synapses | 2002 |
Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis.
Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; RNA, Messenger; Spinal Cord; Symporters; Tritium | 2002 |
Activity-dependent expression of simultaneous glutamatergic and GABAergic neurotransmission from the mossy fibers in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kindling, Neurologic; Mossy Fibers, Hippocampal; Perforant Pathway; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission | 2002 |
Ionotropic glutamate receptors mediate juvenile hormone synthesis in the cockroach, Diploptera punctata.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cockroaches; Corpora Allata; Cycloleucine; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Juvenile Hormones; Kainic Acid; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2002 |
Effects of selective NMDA and non-NMDA blockade in the nucleus accumbens on the plus-maze test.
Topics: Animals; Anxiety; Defecation; Excitatory Amino Acid Antagonists; Male; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 2002 |
Effects of NMDA and non-NMDA ionotropic glutamate receptor antagonists on the development and maintenance of hyperalgesia induced by repeated intramuscular injection of acidic saline.
Topics: 2-Amino-5-phosphonovalerate; Acids; Animals; Drug Administration Schedule; Drug Combinations; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Intramuscular; Male; Motor Activity; Muscle, Skeletal; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Sodium Chloride | 2002 |
AMPA and NMDA receptors mediate synaptic excitation in the rat's inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inferior Colliculi; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2002 |
Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato-sensory cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Somatosensory Cortex; Synapses; Synaptic Transmission | 2002 |
Effects of AMPA-receptor and voltage-sensitive sodium channel blockade on high potassium-induced glutamate release and neuronal death in vivo.
Topics: Amygdala; Animals; Cell Death; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Male; Necrosis; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2002 |
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Consciousness; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Kynurenic Acid; Medulla Oblongata; Microinjections; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Respiratory Mechanics | 2002 |
Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.
Topics: Adenoviridae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain Neoplasms; Calcium; Cell Movement; Genetic Vectors; Glioblastoma; Humans; Imidazoles; Mice; Mice, Nude; Permeability; Quinoxalines; Receptors, AMPA; Tumor Cells, Cultured | 2002 |
NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury.
Topics: Animals; Dizocilpine Maleate; Female; Glucose; Glutamic Acid; Injections, Spinal; Lipid Peroxidation; Mitochondria; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances; Thoracic Vertebrae | 2002 |
A model of atropine-resistant theta oscillations in rat hippocampal area CA1.
Topics: Action Potentials; Animals; Atropine; Dendrites; Excitatory Amino Acid Antagonists; Hippocampus; Interneurons; Male; Neural Inhibition; Parasympatholytics; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Theta Rhythm | 2002 |
Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Glutamic Acid; Kainic Acid; N-Methylaspartate; Osteoblasts; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; Skull | 2002 |
Presynaptic factors in the regulation of DSI expression in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Male; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Signal Transduction; Tetraethylammonium; Tetrodotoxin | 2002 |
Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbonic Anhydrase Inhibitors; Electric Stimulation; Electrophysiology; Epilepsy; Female; GABA Antagonists; Gap Junctions; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 2002 |
Domoic acid neurotoxicity in hippocampal slice cultures.
Topics: Animals; Culture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Indicators and Reagents; Kainic Acid; Microtubule-Associated Proteins; Neurons; Neurotoxins; Propidium; Quinoxalines; Rats; Rats, Wistar | 2002 |
Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons.
Topics: Animals; Apomorphine; Behavior, Animal; Columbidae; Discrimination Learning; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections; Nucleus Accumbens; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Stimulation, Chemical | 2002 |
The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres.
Topics: Alanine; Animals; Animals, Newborn; Benzodiazepines; Benzyl Compounds; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Antagonists; Motor Neurons; Nerve Fibers; Pyrimidinones; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spinal Nerve Roots; Time Factors; Uracil | 2002 |
The epileptogenic effect of seizures induced by hypoxia: the role of NMDA and AMPA/KA antagonists.
Topics: Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Mice; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 2003 |
Both MK801 and NBQX reduce the neuronal damage after impact-acceleration brain injury.
Topics: Amyloid beta-Protein Precursor; Animals; Brain Injuries; Brain Stem; Dizocilpine Maleate; Glial Fibrillary Acidic Protein; Male; Neurons; Quinoxalines; Rats; Rats, Wistar; Thalamus | 2002 |
Role of AMPA and NMDA receptors in the nucleus accumbens shell in turning behaviour of rats: interaction with dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Injections, Intraventricular; Male; Movement; Nucleus Accumbens; Quinoxalines; Quinpirole; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2003 |
Ability of NMDA and non-NMDA receptor antagonists to inhibit cerebral ischemic damage in aged rats.
Topics: Aging; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Telencephalon | 2003 |
Prolonged expression of c-Fos and c-Jun in the cerebral cortex of rats after deltamethrin treatment.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; Insecticides; Male; Nitriles; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrethrins; Quinoxalines; Rats; Rats, Sprague-Dawley | 2003 |
Activation of Ih is necessary for patterning of mGluR and mAChR induced network activity in the hippocampal CA3 region.
Topics: Animals; Carbachol; Cardiotonic Agents; Cholinergic Agonists; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Nerve Net; Patch-Clamp Techniques; Pyramidal Cells; Pyrimidines; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Synaptic Transmission; Theta Rhythm | 2003 |
A role for COX-2 and p38 mitogen activated protein kinase in long-term depression in the rat dentate gyrus in vitro.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dentate Gyrus; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Imidazoles; In Vitro Techniques; Isoenzymes; Long-Term Synaptic Depression; Male; Mitogen-Activated Protein Kinases; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Quinoxalines; Rats; Rats, Wistar; Sulfonamides; Time Factors | 2003 |
Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Laminectomy; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Urethra | 2003 |
Perturbations in three medullary nuclei enhance fractionated breathing in awake goats.
Topics: Animals; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Inhalation; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Respiratory Mechanics; Respiratory Physiological Phenomena; Sleep | 2003 |
Glutamate receptor antagonists modulate heat shock protein response in focal brain ischemia.
Topics: Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP72 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred SHR | 2003 |
Glutamatergic and GABAergic regulation of neural responses in inferior colliculus to amplitude-modulated sounds.
Topics: Acoustic Stimulation; Action Potentials; Animals; Bicuculline; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Inferior Colliculi; Iontophoresis; Male; Neural Inhibition; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2003 |
Networks of neurons coupled to microelectrode arrays: a neuronal sensory system for pharmacological applications.
Topics: Algorithms; Animals; Benzothiadiazines; Biosensing Techniques; Cells, Cultured; Cells, Immobilized; Chick Embryo; Chickens; Dizocilpine Maleate; Microelectrodes; Nerve Net; Quinoxalines; Signal Processing, Computer-Assisted | 2003 |
Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Models, Neurological; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Time Factors; Valine | 2003 |
Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity.
Topics: Apoptosis; Cell Culture Techniques; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-1; Microglia; Multiple Sclerosis; Oligodendroglia; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Tumor Necrosis Factor-alpha | 2003 |
Regulation of backpropagating action potentials in mitral cell lateral dendrites by A-type potassium currents.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Animals; Axons; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2003 |
The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Behavior, Animal; Calcium; Cells, Cultured; Disease Models, Animal; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Forelimb; Glycine; Hand Strength; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Psychomotor Performance; Quinoxalines; Receptors, AMPA | 2003 |
The leading role of membrane Ca(2+)-ATPase in recovery of Ca(2+) homeostasis after glutamate shock.
Topics: Animals; Animals, Newborn; Barium; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Homeostasis; Lithium; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Spectrometry, Fluorescence | 2003 |
Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats.
Topics: Animals; Bridged Bicyclo Compounds; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Nicotine; Pyridines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2003 |
In vitro glutamate-stimulated release of dopamine from nucleus accumbens core and shell of spontaneously hypertensive rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; In Vitro Techniques; Nucleus Accumbens; Perfusion; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA | 2003 |
A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus.
Topics: Animals; Benzylamines; Bicuculline; Biogenic Monoamines; Cerebellum; Dopamine beta-Hydroxylase; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Extracellular Space; Frontal Lobe; GABA Antagonists; Hippocampus; Immunohistochemistry; Kindling, Neurologic; Locus Coeruleus; Male; Neurons; Neurotoxins; Norepinephrine; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Staining and Labeling; Status Epilepticus; Time Factors | 2003 |
Loss of GABAergic neuronal phenotype in primary cerebellar cultures following blockade of glutamate reuptake.
Topics: Animals; Animals, Newborn; Carrier Proteins; Cell Death; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Indicators and Reagents; Membrane Proteins; Membrane Transport Proteins; Neurofilament Proteins; Neurons; Neurotransmitter Uptake Inhibitors; Organic Anion Transporters; Organic Chemicals; Propidium; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2003 |
Multiple sclerosis and glutamate.
Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Receptors, AMPA; Spinal Cord | 2003 |
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycolysis; Hippocampus; Iodoacetates; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Pregnancy; Pyrrolidines; Pyruvic Acid; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2003 |
Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Heart Rate; Hypothalamus; Injections; Kidney; Kynurenic Acid; Male; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2003 |
Inhibitory control of intrinsic hippocampal oscillations?
Topics: Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Methacholine Chloride; Nerve Net; Neural Inhibition; Oscillometry; Periodicity; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Reaction Time; Synapses | 2003 |
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors | 2003 |
In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors | 2003 |
Inhibition of alpha-subunit glycine receptors by quinoxalines.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; Animals; Dose-Response Relationship, Drug; Electrophysiology; GABA-A Receptor Antagonists; Humans; Oocytes; Quinoxalines; Receptors, Glycine; Xenopus laevis | 2003 |
Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision.
Topics: Animals; Behavior, Animal; Diagnosis, Differential; Excitatory Amino Acid Antagonists; Foot; Hyperalgesia; Male; Muscle, Skeletal; Neurotoxins; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord | 2003 |
GABA and glutamate receptors are involved in modulating pacemaker activity in hydra.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Culture Techniques; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hydra; Kainic Acid; Quinoxalines; Receptors, GABA; Receptors, Glutamate | 2003 |
The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro.
Topics: Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Globus Pallidus; Hypoglossal Nerve; In Vitro Techniques; Kinetics; Male; Motor Neurons; Quinoxalines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Ritanserin; Serotonin; Serotonin Antagonists | 2003 |
Agmatine induces glutamate release and cell death in cultured rat cerebellar granule neurons.
Topics: Agmatine; Animals; Botulinum Toxins; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Neurons; Potassium; Quinoxalines; Rats; Tetrazolium Salts; Thiazoles | 2003 |
Direct physiological evidence for synaptic connectivity between medium-sized spiny neurons in rat nucleus accumbens in situ.
Topics: Animals; Axons; Basal Ganglia; Bicuculline; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Neural Pathways; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Receptor Cross-Talk; Synapses | 2004 |
Contribution of spinal glutamatergic mechanisms in heterosegmental antinociception induced by noxious stimulation.
Topics: Animals; Benzoates; Capsaicin; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Isoquinolines; Male; Nociceptors; Pyridines; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Stimulation, Chemical; Substance P | 2003 |
LTP in cultured hippocampal-entorhinal cortex slices from young adult (P25-30) rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Immunoblotting; Immunohistochemistry; Long-Term Potentiation; Nerve Net; Organ Culture Techniques; Picrotoxin; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 2003 |
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).
Topics: Amnesia; Animals; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kynurenic Acid; Male; Mice; N-Methylaspartate; Nootropic Agents; Piperazines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2003 |
Role of the medullary lateral tegmental field in reflex-mediated sympathoexcitation in cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arteries; Cats; Chemoreceptor Cells; Denervation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; Medulla Oblongata; Microinjections; Muscimol; Periaqueductal Gray; Pressoreceptors; Quinoxalines; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Sciatic Nerve; Sodium Cyanide; Sympathetic Nervous System; Trigeminal Nerve | 2004 |
Activation of group III metabotropic glutamate receptors presynaptically reduces both GABAergic and glutamatergic transmission in the rat globus pallidus.
Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; In Vitro Techniques; Internal Capsule; Iontophoresis; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperazines; Propionates; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 2003 |
The glutamatergic N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the joint contribute to the induction, but not maintenance, of arthritic pain in rats.
Topics: Animals; Arthritis, Experimental; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Joints; Male; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Dual roles in feeding for AMPA/kainate receptors: receptor activation or inactivation within distinct hypothalamic regions elicits feeding behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamus; Male; Neural Pathways; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission | 2003 |
Repetitive firing of rat cerebellar parallel fibres after a single stimulation.
Topics: Action Potentials; Administration, Topical; Animals; Cerebellum; Dendrites; Differential Threshold; Electric Conductivity; Electric Stimulation; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA-A Receptor Agonists; In Vitro Techniques; Muscimol; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time | 2004 |
Non-calyceal excitatory inputs mediate low fidelity synaptic transmission in rat auditory brainstem slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2003 |
Spinal control of erection by glutamate in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Catheterization; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Penile Erection; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stimulation, Chemical | 2004 |
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Differential effects of zinc on glutamatergic and GABAergic neurotransmitter systems in the hippocampus.
Topics: Animals; Calcium Channel Blockers; Chelating Agents; Chlorides; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neural Inhibition; Neural Pathways; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Synaptic Transmission; Up-Regulation; Zinc; Zinc Compounds | 2004 |
Measuring synchronization in neuronal networks for biosensor applications.
Topics: Action Potentials; Algorithms; Animals; Bicuculline; Biosensing Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Mice; Mice, Inbred ICR; Microelectrodes; Models, Neurological; Models, Statistical; Nerve Net; Neurons; Quinoxalines; Reproducibility of Results; Sensitivity and Specificity; Spinal Cord; Statistics as Topic; Strychnine | 2004 |
Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Quinoxalines; Receptors, AMPA; Seizures | 2004 |
ZD7288 inhibits postsynaptic glutamate receptor-mediated responses at hippocampal perforant path-granule cell synapses.
Topics: Analysis of Variance; Animals; Cardiotonic Agents; Cesium; Electric Conductivity; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Perforant Pathway; Pyrimidines; Quinoxalines; Receptors, Glutamate; Synapses; Time Factors | 2004 |
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Corpus Striatum; Drug Administration Schedule; Fungicides, Industrial; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Remoxipride; Substance Withdrawal Syndrome; Time Factors; Triazoles | 2004 |
Role of glutamate receptors in the development and maintenance of bladder overactivity after cerebral infarction in the rat.
Topics: Animals; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Urinary Bladder Diseases | 2004 |
5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, Trolox, and Z-VAD-FMK in murine cortical culture.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antimetabolites, Antineoplastic; Antioxidants; Caspase Inhibitors; Cell Culture Techniques; Cell Death; Chromans; Cycloheximide; Cysteine Proteinase Inhibitors; Excitatory Amino Acid Antagonists; Fluorouracil; Mice; Oligodendroglia; Protein Synthesis Inhibitors; Quinoxalines; Receptors, AMPA | 2004 |
Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells.
Topics: alpha-Tocopherol; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cerebellum; Cytochromes c; Dizocilpine Maleate; Drug Interactions; Enzyme Activation; Flow Cytometry; Methamphetamine; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Reactive Oxygen Species | 2004 |
Electrophysiological characterisations of rat lamina I dorsal horn neurones and the involvement of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Male; Nerve Fibers, Unmyelinated; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus.
Topics: Animals; Blotting, Western; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; DNA Primers; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Isoenzymes; Isoquinolines; Male; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stress, Psychological; Up-Regulation | 2004 |
Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate.
Topics: Animals; Calcium; Cell Death; Cell Differentiation; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; Gestational Age; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Kainic Acid; Leukomalacia, Periventricular; Movement Disorders; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Topiramate; Treatment Outcome | 2004 |
Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Axons; Cell Adhesion Molecules; Cytokines; Disease Progression; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Immunoglobulins; Integrins; Mice; Mice, Inbred C57BL; Mucoproteins; Multiple Sclerosis; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Receptors, Glutamate; Treatment Outcome; Weight Gain | 2004 |
NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury.
Topics: Animals; Anticonvulsants; Brain; Cell Death; Disease Models, Animal; DNA Fragmentation; Fructose; Hippocampus; Hypoxia, Brain; In Situ Nick-End Labeling; Kainic Acid; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Seizures; Topiramate | 2004 |
Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord.
Topics: Animals; Cell Count; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries; Time Factors | 2004 |
Schaffer collateral and perforant path inputs activate different subtypes of NMDA receptors on the same CA1 pyramidal cell.
Topics: Animals; Excitatory Postsynaptic Potentials; N-Methylaspartate; Perforant Pathway; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2004 |
Effects of the lurcher mutation on GluR1 desensitization and activation kinetics.
Topics: Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Mice; Mice, Neurologic Mutants; Models, Biological; Monte Carlo Method; Mutation; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA | 2004 |
Brain injury induced by intracerebral injection of interleukin-1beta and tumor necrosis factor-alpha in the neonatal rat.
Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Caspase 3; Caspases; Cerebral Cortex; Excitatory Amino Acid Antagonists; Humans; In Situ Nick-End Labeling; Infant; Inflammation; Interleukin-1; Myelin Basic Protein; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tumor Necrosis Factor-alpha | 2004 |
Long-term synaptic changes induced in the cerebellar cortex by fear conditioning.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cerebellar Cortex; Conditioning, Psychological; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fear; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Motor Activity; Pain Measurement; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Reaction Time; Retention, Psychology; Synapses; Time Factors | 2004 |
Retinal bipolar cell input mechanisms in giant danio. I. Electroretinographic analysis.
Topics: Aminobutyrates; Anesthetics, Local; Animals; Aspartic Acid; Cyclopentanes; Dose-Response Relationship, Radiation; Drug Interactions; Electroretinography; Excitatory Amino Acid Agonists; GABA Antagonists; Glycine; Glycine Agents; Neurons; Photic Stimulation; Picrotoxin; Quinoxalines; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Strychnine; Synaptic Transmission; Tetrodotoxin; Visual Pathways; Zebrafish | 2005 |
GABA uptake via GABA transporter-1 modulates GABAergic transmission in the immature hippocampus.
Topics: Animals; Animals, Newborn; Bicuculline; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Membrane Transport Proteins; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin | 2004 |
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Benzoxazines; Brain Stem; Calcium Signaling; Cannabinoid Receptor Modulators; Endocannabinoids; Evoked Potentials, Auditory, Brain Stem; Glycine; Ion Transport; Morpholines; Naphthalenes; Nerve Endings; Patch-Clamp Techniques; Picrotoxin; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols; Scopolamine; Synaptic Transmission; Xanthenes | 2004 |
Amygdala central nucleus function is necessary for learning but not expression of conditioned visual orienting.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Classical; Excitatory Amino Acid Antagonists; Feeding Behavior; Learning; Male; Orientation; Photic Stimulation; Quinoxalines; Rats; Rats, Long-Evans; Reinforcement, Psychology | 2004 |
Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis.
Topics: Animals; Carbon Monoxide Poisoning; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Wakefulness | 2004 |
Functional topology of the mossy fibre-granule cell--Purkinje cell system revealed by imaging of intrinsic fluorescence in mouse cerebellum.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebellum; Chromones; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescence; GABA Antagonists; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; Nerve Fibers; Neurons; Picrotoxin; Quinoxalines; Time Factors | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic pain.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Analysis of Variance; Animals; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kaolin; Male; Neural Inhibition; Neurons; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Male; Morphine; Narcotics; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors | 2004 |
Slow actions of neuroactive steroids at GABAA receptors.
Topics: Animals; Binding Sites; Cell Membrane; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Cyclodextrins; Hippocampus; Ion Channel Gating; Ion Transport; Kinetics; Ligands; Neurons; Oocytes; Patch-Clamp Techniques; Pregnanolone; Protein Binding; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection; Xenopus | 2004 |
Acute nociceptive somatic stimulus sensitizes neurones in the spinal cord to colonic distension in the rat.
Topics: Acids; Animals; Catheterization; Colon; Excitatory Amino Acid Antagonists; Lumbar Vertebrae; Male; Neurons, Afferent; Nociceptors; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Stimulation, Chemical | 2004 |
Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Microtubule-Associated Proteins; Neocortex; Neurons; Patch-Clamp Techniques; Protein Conformation; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Animals, Newborn; Annexin A5; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromatin Assembly and Disassembly; Cystine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fluoresceins; G(M1) Ganglioside; Glial Fibrillary Acidic Protein; Glucose; Glutamic Acid; Hypoxia; Immunohistochemistry; Indoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Myelin Proteins; Myelin-Associated Glycoprotein; Nogo Proteins; Oligodendroglia; Oligopeptides; Peroxides; Phosphorylation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Signal Transduction; Time Factors | 2004 |
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Topics: Animals; Bicuculline; Blotting, Western; Calmodulin-Binding Proteins; Carrier Proteins; Cell Count; Cell Differentiation; Cell Lineage; Cells, Cultured; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; GABA Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Homeodomain Proteins; Immunohistochemistry; Indoles; Intermediate Filament Proteins; Membrane Potentials; Mice; Nerve Tissue Proteins; Nestin; Neuroglia; Neurogranin; Neurons; Paired Box Transcription Factors; Patch-Clamp Techniques; PAX6 Transcription Factor; Quinoxalines; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, AMPA; Receptors, Nerve Growth Factor; Repressor Proteins; Stem Cells; Synaptophysin; Tetrodotoxin; Time Factors; Tretinoin; Tubulin; Valine | 2004 |
Time window and pharmacological characterisation of kainate-mediated preconditioning in organotypic rat hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Brain Injuries; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Brain; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Glutamates; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Mice; Mice, Knockout; Patch-Clamp Techniques; Piperazines; Purkinje Cells; Quinoxalines; RNA; Stem Cells; Synaptic Transmission; Time Factors | 2004 |
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Crosses, Genetic; Dentate Gyrus; Disease Models, Animal; Down Syndrome; Evoked Potentials; Female; GABA-A Receptor Antagonists; Gene Dosage; Glycine; Hippocampus; Long-Term Potentiation; Magnesium; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Species Specificity; Trisomy | 2004 |
Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice.
Topics: 4-Aminopyridine; Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cortical Synchronization; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Synaptic Transmission | 2005 |
Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blockers; Cell Death; Clonazepam; Dantrolene; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; Glucose; Hippocampus; Hypoxia; In Situ Nick-End Labeling; Indoles; Intracellular Space; Ion Exchange; Lidocaine; Mibefradil; Nimodipine; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Thiazepines; Thiourea; Time Factors | 2004 |
Mechanisms of fast ripples in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Hippocampus; Kinetics; Male; Periodicity; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2004 |
Role of ionotropic glutamatergic and GABAergic inputs on the firing activity of neurons in the external pallidum in awake monkeys.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; Macaca; Motor Cortex; Neurons; Pyridazines; Quinoxalines; Wakefulness | 2004 |
Nitric oxide inhibits complex I following AMPA receptor activation via peroxynitrite.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Cyclic GMP; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Kainic Acid; Microtubule-Associated Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Proton Pumps; Quinoxalines; Rats; Receptors, AMPA; Tyrosine | 2004 |
High activity of K+-dependent plasmalemmal Na+/Ca2+ exchangers in hippocampal CA1 neurons.
Topics: Animals; Calcium; Cells, Cultured; Cesium; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Gluconates; Gramicidin; Hippocampus; Ion Transport; Lithium; Male; Meglumine; Neurons; Potassium; Pregnancy; Quinoxalines; Rats; Sodium; Sodium-Calcium Exchanger; Thiourea | 2004 |
Hippocampal N-methyl-D-aspartate receptor-mediated encoding and retrieval processes in spatial working memory: delay-interposed radial maze performance in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Memory, Short-Term; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
NK1 receptor activation leads to enhancement of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse.
Topics: Animals; Bicuculline; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Quinoxalines; Receptors, Neurokinin-1; Substantia Gelatinosa; Synaptic Transmission | 2004 |
NBQX does not affect learning and memory tasks in mice: a comparison with D-CPPene and ifenprodil.
Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Mice; Neuropsychological Tests; Piperazines; Piperidines; Quinoxalines; Reaction Time | 1992 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
Simultaneous contribution of two rod pathways to AII amacrine and cone bipolar cell light responses.
Topics: Amacrine Cells; Animals; Benzodiazepines; Benzothiadiazines; Diagnostic Imaging; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluorescein; GABA Antagonists; Glycine Agents; In Vitro Techniques; Light; Male; Membrane Potentials; Models, Biological; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rabbits; Retina; Retinal Rod Photoreceptor Cells; Strychnine; Synapses; Synaptic Transmission; Visual Pathways | 2005 |
Fear-potentiated startle in rats is mediated by neurons in the deep layers of the superior colliculus/deep mesencephalic nucleus of the rostral midbrain through the glutamate non-NMDA receptors.
Topics: Animals; Excitatory Amino Acid Antagonists; Fear; Male; Mesencephalon; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Reflex, Startle; Superior Colliculi | 2004 |
p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells.
Topics: Animals; Apoptosis; Benzodiazepines; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Cyclin-Dependent Kinase Inhibitor p21; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Quinoxalines; Receptors, AMPA | 2004 |
The impact of excitotoxic blockade on the evolution of injury following combined mechanical and hypoxic insults in primary rat neuronal culture.
Topics: Animals; Anticonvulsants; Cell Hypoxia; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Female; Neurons; Pregnancy; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Polyamines modulate AMPA receptor-dependent synaptic responses in immature layer v pyramidal neurons.
Topics: Age Factors; Animals; Animals, Newborn; Blotting, Western; Eflornithine; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Neocortex; Neuronal Plasticity; Patch-Clamp Techniques; Polyamines; Pyramidal Cells; Quinoxalines; Rats; Receptors, AMPA; Spermine; Synapses; Time Factors | 2005 |
Role of glutamate ionotropic receptors in the dorsomedial hypothalamic nucleus on anxiety and locomotor behavior.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Dorsomedial Hypothalamic Nucleus; Male; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 2004 |
Activity-dependent maturation of excitatory synaptic connections in solitary neuron cultures of mouse neocortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Neocortex; Neurons; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Statistics, Nonparametric; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Electroencephalography; Electromyography; Epilepsies, Partial; Exploratory Behavior; Male; Motor Activity; Neocortex; Phenytoin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetanus Toxin | 2005 |
Simultaneous AMPA/kainate receptor blockade and dopamine D(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Behavior, Animal; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Male; Microinjections; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Kainic Acid; Regression Analysis; Reward; Tetrahydronaphthalenes; Ventral Tegmental Area | 2005 |
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Herpesvirus 1, Suid; Homeostasis; In Situ Hybridization; Interneurons; Isoenzymes; Kynurenic Acid; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord; Strychnine | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Local calcium transients regulate the spontaneous motility of dendritic filopodia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Signaling; Cell Movement; Cells, Cultured; Dendrites; Diagnostic Imaging; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Indoles; Pseudopodia; Pyramidal Cells; Pyridazines; Quinoxalines; Rats; Synapses; Time Factors | 2005 |
Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons.
Topics: Age Factors; Alamethicin; Analysis of Variance; Animals; Animals, Newborn; Brain Diseases; Calcium; Calcium Isotopes; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Count; Cell Death; Cell Fractionation; Cells, Cultured; Cerebellum; Diagnostic Imaging; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; Glutamic Acid; Glycine; Hydro-Lyases; Indoles; Intracellular Space; Ionophores; Male; Mitochondria; Neurons; Propidium; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2005 |
The HVC microcircuit: the synaptic basis for interactions between song motor and vocal plasticity pathways.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Basal Ganglia; Brain Mapping; Efferent Pathways; Electrophysiology; Finches; GABA-A Receptor Antagonists; Interneurons; Learning; Male; Nerve Net; Neuronal Plasticity; Neurons; Picrotoxin; Prosencephalon; Quinoxalines; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vocalization, Animal | 2005 |
Effects of Na+-Ca2+ exchanger activity on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolone-propionate-induced Ca2+ influx in cerebellar Purkinje neurons.
Topics: Agatoxins; Animals; Animals, Newborn; Bepridil; Calbindins; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Diagnostic Imaging; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Isoxazoles; Microscopy, Confocal; Oligonucleotides, Antisense; Polyamines; Propionates; Purkinje Cells; Quinoxalines; Rats; S100 Calcium Binding Protein G; Sodium; Sodium Channel Blockers; Sodium-Calcium Exchanger; Thiourea | 2005 |
NMDA or AMPA/kainate receptor blockade prevents acquisition of conditioned place preference induced by D(2/3) dopamine receptor stimulation in rats.
Topics: Animals; Choice Behavior; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tetrahydronaphthalenes | 2005 |
Multiple pathways of apolipoprotein E signaling in primary neurons.
Topics: Analysis of Variance; Androstadienes; Animals; Apolipoproteins E; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Models, Neurological; Nerve Tissue Proteins; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinoxalines; Signal Transduction; src-Family Kinases; Time Factors; Wortmannin | 2005 |
Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neuronal Plasticity; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Cardiovascular response to a group III mGluR agonist in NTS requires NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Cardiovascular System; Excitatory Amino Acid Agonists; Glycine; Glycine Agents; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine | 2005 |
In vivo neuroprotective effects of the novel imidazolyl nitrone free-radical scavenger (Z)-alpha-[2-thiazol-2-yl)imidazol-4-yl]-N-tert-butylnitrone (S34176).
Topics: Animals; Brain Ischemia; Cell Survival; Corpus Striatum; Dopamine; Free Radical Scavengers; Hippocampus; Imidazoles; Kainic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Nitrogen Oxides; Quinoxalines; Rats; Rats, Wistar | 2005 |
Fast neurotransmission in the rat medial preoptic nucleus.
Topics: Animals; Dizocilpine Maleate; In Vitro Techniques; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2005 |
Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids.
Topics: Animals; Cell Count; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Green Fluorescent Proteins; Hormone Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Narcotics; Neurons; Patch-Clamp Techniques; Pro-Opiomelanocortin; Proglumide; Proto-Oncogene Proteins c-fos; Quinoxalines; Solitary Nucleus; Time Factors; Visceral Afferents | 2005 |
AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Bridged Bicyclo Compounds; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Fluvoxamine; Immobility Response, Tonic; Male; Mice; Mice, Inbred ICR; Microdialysis; Prefrontal Cortex; Quinoxalines; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Serotonin | 2005 |
Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures.
Topics: Animals; Dendrites; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Kinetics; Mice; N-Methylaspartate; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Tetrodotoxin | 2005 |
Antinociceptive interactions between intrathecal gabapentin and MK801 or NBQX in rat formalin test.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2005 |
Group III metabotropic glutamate receptors and exocytosed protons inhibit L-type calcium currents in cones but not in rods.
Topics: Animals; Calcium; Calcium Channels, L-Type; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guanosine Diphosphate; HEPES; In Vitro Techniques; Light; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Propionates; Protons; Quinoxalines; Receptors, AMPA; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Salamandridae; Synaptic Transmission; Thionucleotides; Vision, Ocular; Visual Pathways | 2005 |
Slow and fast inhibition and an H-current interact to create a theta rhythm in a model of CA1 interneuron network.
Topics: Animals; Computer Simulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Ion Channels; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Inhibition; Neural Networks, Computer; Patch-Clamp Techniques; Periodicity; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Theta Rhythm | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hot Temperature; Hyperalgesia; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Nociceptors; Pain, Postoperative; Physical Stimulation; Proto-Oncogene Proteins c-fos; Quinoxalines; Skin; TRPV Cation Channels | 2005 |
Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 region.
Topics: Animals; Blotting, Western; Body Weight; Brain; Central Nervous System Depressants; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Organ Size; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Valine | 2005 |
Mechanical loading modulates glutamate receptor subunit expression in bone.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Biomechanical Phenomena; Bone and Bones; Bone Resorption; Calcification, Physiologic; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Female; Forelimb; Immunohistochemistry; Isoenzymes; Leg Bones; Osteoclasts; Osteocytes; Pliability; Protein Subunits; Quinoxalines; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tartrate-Resistant Acid Phosphatase; Weight-Bearing | 2005 |
Long-term potentiation of neuronal glutamate transporters.
Topics: Amino Acid Transport System X-AG; Animals; In Vitro Techniques; Long-Term Potentiation; Neurons; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
AMPA/kainate receptors mediate axonal morphological disruption in hypoxic white matter.
Topics: Action Potentials; Animals; Axons; Brain; Excitatory Amino Acid Antagonists; Hypoxia, Brain; Immunohistochemistry; Mice; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid | 2005 |
Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Calcium; Case-Control Studies; Cell Survival; Cells, Cultured; Cerebrospinal Fluid; Diagnostic Imaging; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Humans; Intracellular Fluid; Male; Motor Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Spinal Cord; Time Factors | 2005 |
NMDA receptor subunit-dependent [Ca2+] signaling in individual hippocampal dendritic spines.
Topics: Animals; Calcium Signaling; Dendritic Spines; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses | 2005 |
Retrograde endocannabinoid signaling in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala.
Topics: Amygdala; Animals; Brain; Cannabinoids; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses | 2005 |
Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Brain Chemistry; Carbon Radioisotopes; Cerebrovascular Circulation; Deoxyglucose; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Male; Mice; Mice, Inbred C57BL; Quinoxalines | 2005 |
Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons.
Topics: Animals; Bicuculline; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diagnostic Imaging; Diltiazem; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; K Cl- Cotransporters; Muscimol; Neurons; Nimodipine; Potassium Chloride; Pregnancy; Quinoxalines; Rats; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Time Factors | 2005 |
Selective sparing of hippocampal CA3 cells following in vitro ischemia is due to selective inhibition by acidosis.
Topics: Acidosis; Animals; Animals, Newborn; Calcium; Cell Death; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hydrogen-Ion Concentration; Ischemia; Mice; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Time Factors; Valine | 2005 |
Programmed and induced phenotype of the hippocampal granule cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calbindins; Cells, Cultured; Dynorphins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Neuronal Plasticity; Organ Culture Techniques; Phenotype; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S100 Calcium Binding Protein G; Synapses; Vesicular Glutamate Transport Protein 1; Vesicular Inhibitory Amino Acid Transport Proteins | 2005 |
Presynaptic angiotensin II AT1 receptors enhance inhibitory and excitatory synaptic neurotransmission to motoneurons and other ventral horn neurons in neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Angiotensin II; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; In Vitro Techniques; Laminectomy; Male; Motor Neurons; Neural Inhibition; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Spinal Cord; Strychnine; Synaptic Transmission; Tetrodotoxin | 2005 |
In vivo calcium imaging of circuit activity in cerebellar cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Calcium; Cerebellar Cortex; Dendrites; Diagnostic Imaging; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Nerve Net; Neurons; Poloxamer; Quinoxalines; Rats; Rats, Wistar; Valine | 2005 |
Regulation of IPSP theta rhythm by muscarinic receptors and endocannabinoids in hippocampus.
Topics: Action Potentials; Amino Acids; Animals; Cannabinoid Receptor Modulators; Carbachol; Cholinergic Agonists; Endocannabinoids; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Neural Inhibition; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Spectrum Analysis; Synapses; Theta Rhythm; Time Factors; Xanthenes | 2005 |
Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca2+ indicator protein.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Signaling; Cerebellum; Chromones; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Fluorescence Recovery After Photobleaching; Gene Expression Regulation; Immunohistochemistry; In Vitro Techniques; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Fibers; Neurons; Neuropeptides; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Promoter Regions, Genetic; Quinoxalines; Shaw Potassium Channels | 2005 |
SK channel regulation of dendritic excitability and dendrodendritic inhibition in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Apamin; Cadmium; Calcium; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Magnesium; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Pyridazines; Quinoxalines; Synaptic Transmission; Tetraethylammonium; Tetrodotoxin; Time Factors | 2005 |
Silent synapses in a thalamo-cortical circuit necessary for song learning in zebra finches.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Finches; In Vitro Techniques; Learning; Lysine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Patch-Clamp Techniques; Quinoxalines; Synapses; Thalamus; Vocalization, Animal | 2005 |
The effects of AMPA receptor antagonists in models of stroke and neurodegeneration.
Topics: Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Brain; Brain Ischemia; Cell Survival; Chickens; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred Strains; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Retina; Seizures; Stroke | 2005 |
Millisecond-timescale, genetically targeted optical control of neural activity.
Topics: Action Potentials; Algal Proteins; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Radiation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Hippocampus; Ion Channel Gating; Ion Channels; Neural Inhibition; Neurons; Optics and Photonics; Photobiology; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Reproducibility of Results; Rhodopsin; Synaptic Transmission; Time Factors; Transfection | 2005 |
Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cannabinoids; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 4; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Membrane Potentials; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Synapses | 2005 |
Recurrent mossy fibers establish aberrant kainate receptor-operated synapses on granule cells from epileptic rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Mossy Fibers, Hippocampal; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Synapses | 2005 |
Ventral tegmental area involvement in pair bonding in male prairie voles.
Topics: Animals; Arvicolinae; Behavior, Animal; Bicuculline; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Male; Pair Bond; Quinoxalines; Random Allocation; Reaction Time; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Recruitment of local excitatory circuits in the superior colliculus following deafferentation and the regeneration of retinocollicular inputs.
Topics: Action Potentials; Animals; Animals, Newborn; Axons; Axotomy; Decerebrate State; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Antagonists; In Vitro Techniques; Nerve Net; Neurons; Peripheral Nerves; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Regeneration; Retinal Ganglion Cells; Superior Colliculi; Synaptic Transmission; Transplants; Visual Cortex; Visual Pathways | 2005 |
Sequential involvement of distinct glutamate receptors in domoic acid-induced neurotoxicity in rat mixed cortical cultures: effect of multiple dose/duration paradigms, chronological age, and repeated exposure.
Topics: Animals; Blotting, Western; Cell Survival; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Excitatory Amino Acid Antagonists; Fetus; Immunochemistry; Kainic Acid; Marine Toxins; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2006 |
A comparison of release kinetics and glutamate receptor properties in shaping rod-cone differences in EPSC kinetics in the salamander retina.
Topics: Animals; Benzodiazepines; Benzothiadiazines; Calcium; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Kinetics; Models, Biological; Neurotransmitter Agents; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Retinal Bipolar Cells; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Retinal Rod Photoreceptor Cells; Synaptic Transmission; Synaptic Vesicles; Urodela | 2005 |
alpha1-Adrenergic modulation of synaptic input to Purkinje neurons in rat cerebellar brain slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Animals, Newborn; Cerebellum; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Isoproterenol; Membrane Potentials; Norepinephrine; Patch-Clamp Techniques; Phentolamine; Phenylephrine; Picrotoxin; Prazosin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Synapses; Tetrodotoxin; Time Factors | 2005 |
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Histocytochemistry; Hypoxia; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; Necrosis; Neurofilament Proteins; Neurons; Neuroprotective Agents; Propidium; Quinoxalines; Rats; Receptors, Glutamate; Time Factors | 2005 |
Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Binding Sites; Brain; Calcium; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Motor Activity; N-Methylaspartate; Neurons; Polyvinyls; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Time Factors | 2005 |
Responses of neurons in the rat's ventral nucleus of the lateral lemniscus to monaural and binaural tone bursts.
Topics: Acoustic Stimulation; Action Potentials; Animals; Electrophysiology; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Male; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Time Factors; Ventral Thalamic Nuclei | 2006 |
Slow oscillatory activity of rat globus pallidus neurons in vitro.
Topics: Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Biological Clocks; Cadmium Chloride; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Piperazines; Pyridazines; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors | 2006 |
Involvement of the CA3-CA1 synapse in the acquisition of associative learning in behaving mice.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amnesia, Anterograde; Amnesia, Retrograde; Animals; Association Learning; Blinking; Conditioning, Classical; Electromyography; Electroshock; Excitatory Postsynaptic Potentials; Extinction, Psychological; Habituation, Psychophysiologic; Hippocampus; Learning Disabilities; Long-Term Potentiation; Male; Mental Recall; Mice; Mice, Inbred C57BL; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Trigeminal Nerve | 2006 |
Functional characterisation of homomeric ionotropic glutamate receptors GluR1-GluR6 in a fluorescence-based high throughput screening assay.
Topics: Aniline Compounds; Benzothiadiazines; Calcium; Cell Line; Combinatorial Chemistry Techniques; Concanavalin A; Drug Evaluation, Preclinical; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescence; Glutamic Acid; Humans; Kainic Acid; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Signal Transduction; Xanthenes | 2006 |
Alcohol potently modulates climbing fiber-->Purkinje neuron synapses: role of metabotropic glutamate receptors.
Topics: Alanine; Animals; Aspartic Acid; Disease Models, Animal; Ethanol; Long-Term Synaptic Depression; Male; Nerve Fibers; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses; Xanthenes | 2006 |
Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Benzodiazepines; Blotting, Western; Calcium; Carbachol; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Movement; Cells, Cultured; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fibronectins; Glutamic Acid; Immunohistochemistry; Immunoprecipitation; Integrin alphaV; Ionophores; Kainic Acid; Models, Biological; Myelin Proteolipid Protein; Myelin Sheath; Oligodendroglia; Pertussis Toxin; Quinoxalines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptors, AMPA; Ruthenium Red; Stem Cells; Thapsigargin | 2006 |
Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Topics: Animals; Antirheumatic Agents; Benzodiazepines; Benzodiazepinones; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Diclofenac; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibitory Concentration 50; Methotrexate; Naproxen; Pyrazoles; Quinoxalines; Sulfasalazine; Sulfonamides; Synovial Membrane | 2006 |
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis | 2006 |
Blanes cells mediate persistent feedforward inhibition onto granule cells in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Cadmium; Chelating Agents; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lighting; Membrane Potentials; Models, Neurological; Nerve Net; Neural Inhibition; Olfactory Bulb; Organic Chemicals; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Estrogens; Female; Glutamic Acid; N-Methylaspartate; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Urethra | 2006 |
Preservation of the direct and indirect pathways in an in vitro preparation of the mouse basal ganglia.
Topics: Animals; Animals, Newborn; Basal Ganglia; Bicuculline; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Patch-Clamp Techniques; Quinoxalines | 2006 |
Double dissociation in the neural substrates of acute opiate dependence as measured by withdrawal-potentiated startle.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Fear; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2006 |
Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function.
Topics: Animals; Animals, Newborn; Benzimidazoles; Brain; Calcium; Carbocyanines; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia; In Situ Nick-End Labeling; Ionophores; Mitochondria; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Involvement of mu- and delta-opioid receptors in the antinociceptive effects induced by AMPA receptor antagonist in the spinal cord of rats.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Naltrexone; Pain Measurement; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Wakefulness | 2006 |
Medullary lateral tegmental field neurons influence the timing and pattern of phrenic nerve activity in cats.
Topics: Animals; Cats; Excitatory Amino Acid Antagonists; Exhalation; GABA Antagonists; Glycine Agents; Inhalation; Medulla Oblongata; Motor Neurons; Nitrogen Mustard Compounds; Phrenic Nerve; Pyridazines; Quinoxalines; Receptors, Amino Acid; Receptors, GABA-A; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Respiratory Center; Respiratory Mechanics; Strychnine; Time Factors | 2006 |
Serum-dependence of AMPA receptor-mediated proliferation in glioma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cattle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression; Glioma; Glutamic Acid; Humans; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Serum | 2006 |
An AMPA glutamatergic receptor activation-nitric oxide synthesis step signals transsynaptic apoptosis in limbic cortex.
Topics: Animals; Apoptosis; Cell Count; Cerebral Cortex; DNA Fragmentation; Fluorescent Antibody Technique; Immunohistochemistry; Indazoles; Interneurons; Limbic System; Male; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type I; Olfactory Bulb; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Signal Transduction; Synapses | 2006 |
Injection of l-glutamate into medial prefrontal cortex induces cardiovascular responses through NMDA receptor - nitric oxide in rat.
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Male; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Hypoxia in presence of blockers of excitotoxicity induces a caspase-dependent neuronal necrosis.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Caspases; Cell Survival; Cells, Cultured; Dentate Gyrus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Hypoxia; L-Lactate Dehydrogenase; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Mitochondria; Necrosis; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Sodium Cyanide | 2006 |
In vivo electrical stimulation of rabbit retina: effect of stimulus duration and electrical field orientation.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Electric Stimulation; Electroretinography; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Neurons, Afferent; Quinoxalines; Rabbits; Retina; Retinal Ganglion Cells; Time Factors; Visual Cortex | 2006 |
[Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision].
Topics: Animals; Calcium; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Mechanoreceptors; Muscle, Skeletal; Neurotoxins; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord | 2006 |
BMAA selectively injures motor neurons via AMPA/kainate receptor activation.
Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Survival; Cells, Cultured; Cyanobacteria Toxins; Cycas; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Mice; Motor Neurons; Neurotoxins; Plant Extracts; Plant Poisoning; Quinoxalines; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Seeds; Spinal Cord | 2006 |
Physiological activity depresses synaptic function through an effect on vesicle priming.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Microscopy, Electron, Transmission; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Rats; Synapses; Synaptic Transmission; Synaptic Vesicles; Vesicular Glutamate Transport Protein 1 | 2006 |
It is AMPA receptor, not kainate receptor, that contributes to the NBQX-induced antinociception in the spinal cord of rats.
Topics: Analgesics; Animals; Concanavalin A; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Pain Measurement; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord | 2006 |
Sustained elevation of dendritic calcium evokes widespread endocannabinoid release and suppression of synapses onto cerebellar Purkinje cells.
Topics: Animals; Calcium; Cannabinoid Receptor Modulators; Cerebellum; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Time Factors | 2006 |
Suprachiasmatic nucleus communicates with anterior thalamic paraventricular nucleus neurons via rapid glutamatergic and gabaergic neurotransmission: state-dependent response patterns observed in vitro.
Topics: Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Midline Thalamic Nuclei; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Synaptic Transmission | 2006 |
An ex vivo preparation of mature mice spinal cord to study synaptic transmission on motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Male; Mice; Mice, Inbred C57BL; Motor Neurons; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Solutions; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 2007 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Glutamate receptor-mediated inhibition of L-glutamate efflux from cerebral cortex in vitro.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glucose; Glutamic Acid; Hypoxia; In Vitro Techniques; Neural Inhibition; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Time Factors | 2006 |
Different effects of nonNMDA and NMDA receptor antagonists (NBQX and dizocilpine) on cortical epileptic afterdischarges in rats.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Electroencephalography; Epilepsy; Evoked Potentials; Excitatory Amino Acid Antagonists; Quinoxalines; Rats; Rats, Wistar | 2006 |
Nitrous oxide (N2O) pre- and postsynaptically attenuates NMDA receptor-mediated neurotransmission in the amygdala.
Topics: Amygdala; Analgesics, Non-Narcotic; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Lasers; Male; Mice; Mice, Inbred C57BL; Nitrous Oxide; Oxygen; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2007 |
Block of kainate receptor desensitization uncovers a key trafficking checkpoint.
Topics: Animals; Cells, Cultured; Cysteine; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Kainic Acid; Membrane Potentials; Models, Biological; Mutation; Neurons; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Transport; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Structure-Activity Relationship; Transfection; Xenopus | 2006 |
Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation.
Topics: Animals; Blotting, Western; Cannabinoids; Demyelinating Diseases; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Mice; Multiple Sclerosis, Chronic Progressive; Neuroprotective Agents; Quinoxalines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord | 2007 |
Inhibition of stress-induced adrenocorticotropin and prolactin secretion mediating hypophysiotropic factors by antagonist of AMPA type glutamate receptor.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Dopamine; Male; Median Eminence; Prolactin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Restraint, Physical; Stress, Psychological; Tyrosine 3-Monooxygenase | 2007 |
The spatial organization of long-term synaptic plasticity at the input stage of cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Brain Mapping; Calcium Signaling; Cerebellar Cortex; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Interneurons; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Potentials; Microelectrodes; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2007 |
Synaptic modifications at the CA3-CA1 synapse after chronic AMPA receptor blockade in rat hippocampal slices.
Topics: Animals; Cells, Cultured; Dendritic Cells; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Neuronal Plasticity; Pyramidal Cells; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2007 |
Contribution of NMDA and AMPA receptors to temporal patterning of auditory responses in the inferior colliculus.
Topics: Acoustic Stimulation; Action Potentials; Animals; Chiroptera; Excitatory Amino Acid Antagonists; Inferior Colliculi; Neurons; Piperazines; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2007 |
Involvement of Na+-Ca2+ exchanger on metabotropic glutamate receptor 1-mediated [Ca2+]i transients in rat cerebellar Purkinje neurons.
Topics: Animals; Animals, Newborn; Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Antagonists; Methoxyhydroxyphenylglycol; Oligodeoxyribonucleotides, Antisense; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Sodium-Calcium Exchanger; Thiourea | 2007 |
Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine | 2007 |
Cardiovascular effects of L-glutamate microinjection in the supraoptic nucleus of unanaesthetized rats.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Excitatory Amino Acid Antagonists; Ganglionic Blockers; Glutamic Acid; Heart Rate; Isoquinolines; Male; Microinjections; Pentolinium Tartrate; Quinoxalines; Rats; Rats, Wistar; Supraoptic Nucleus; Vasopressins | 2007 |
Local generation of theta-frequency EEG activity in the parasubiculum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Electric Stimulation; Electrodes; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Antagonists; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Long-Evans; Synaptic Transmission; Theta Rhythm | 2007 |
Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamus.
Topics: Androgens; Animals; Animals, Newborn; Dendrites; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Hypothalamus; Kainic Acid; Male; Microfilament Proteins; Nerve Tissue Proteins; Neurons; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Sex Characteristics; Silver Staining; Testosterone | 2007 |
Hippocampal activity, but not plasticity, is required for early consolidation of fear conditioning with a short trace interval.
Topics: Animals; Conditioning, Classical; Excitatory Amino Acid Antagonists; Fear; GABA Agonists; Hippocampus; Muscimol; Neuronal Plasticity; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
NMDA receptors in preBotzinger complex neurons can drive respiratory rhythm independent of AMPA receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Magnesium; Neurons; Patch-Clamp Techniques; Periodicity; Potassium; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Respiratory Center; Respiratory Mechanics; Synaptic Transmission | 2007 |
Activity-dependent presynaptic and postsynaptic structural plasticity in the mature cerebellum.
Topics: Animals; Cerebellum; Dendritic Spines; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Microscopy, Electron; Neuronal Plasticity; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 2007 |
Impact of intertrigeminal region AMPA receptor blockade on respiratory responses in rats.
Topics: Animals; Apnea; Glutamic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex; Respiratory Mechanics; Serotonin; Trigeminal Nerve; Trigeminal Nuclei; Vagus Nerve | 2007 |
Paired-pulse ratio of synaptically induced transporter currents at hippocampal CA1 synapses is not related to release probability.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Neurons; Probability; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Theophylline | 2007 |
Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Models, Neurological; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Somatosensory Cortex | 2007 |
Biphasic modulation of GABA release from stellate cells by glutamatergic receptor subtypes.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebellum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Morpholines; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Pyrazoles; Quinoxalines; Receptors, AMPA | 2007 |
Differential regulation of glutamate receptor-mediated BDNF mRNA expression in the cerebellum and its defects in stargazer mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium Channels; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; In Situ Hybridization; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neurons; Protein Binding; Quinoxalines; Receptors, Glutamate; RNA, Messenger; Time Factors | 2007 |
Spinal AMPA receptor inhibition attenuates mechanical allodynia and neuronal hyperexcitability following spinal cord injury in rats.
Topics: Animals; Axotomy; Excitatory Amino Acid Antagonists; Hindlimb; Injections, Spinal; Male; Neuralgia; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recovery of Function; Spinal Cord Injuries | 2007 |
Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation.
Topics: Alanine; Animal Testing Alternatives; Animals; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; L-Lactate Dehydrogenase; Propidium; Quinoxalines; Rats; Staining and Labeling; Tissue Culture Techniques | 2007 |
Suprachiasmatic modulation of noradrenaline release in the ventrolateral preoptic nucleus.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; Preoptic Area; Quinoxalines; Rats; Suprachiasmatic Nucleus; Yohimbine | 2007 |
The relationship between blood flow and neuronal activity in the rodent olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Benzaldehydes; Blood Circulation Time; Calcium; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Glomerular Mesangium; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Transgenic; Microscopy, Confocal; Neurons; Odorants; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 2007 |
Climbing fiber-triggered metabotropic slow potentials enhance dendritic calcium transients and simple spike firing in cerebellar Purkinje cells.
Topics: Aniline Compounds; Animals; Aspartic Acid; Calcium; Dendrites; Excitatory Amino Acid Antagonists; Fluoresceins; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2007 |
Glutamatergic ionotropic blockade within accumbens disrupts working memory and might alter the endocytic machinery in rat accumbens and prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; Adaptor Protein Complex 2; Animals; Behavior, Animal; Endocytosis; Excitatory Amino Acid Antagonists; Glutamine; Immunoblotting; Male; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2007 |
AMPA receptor antagonists reverse effects of extended habit training on signaled food approach responding in rats.
Topics: Animals; Appetitive Behavior; Behavior, Animal; Benzazepines; Benzodiazepines; Conditioning, Classical; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Food; Habits; Injections, Intraperitoneal; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Sound; Time Factors | 2007 |
Blockade of the metabotropic glutamate 2/3 receptors enhances social memory via the AMPA receptor in rats.
Topics: Animals; Bridged Bicyclo Compounds; Dicarboxylic Acids; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Memory, Short-Term; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate | 2007 |
Interaction between glutamatergic and nitrergic mechanisms mediating cardiovascular responses to L-glutamate injection in the diagonal band of Broca in anesthetized rats.
Topics: Anesthesia; Animals; Arginine; Benzoates; Blood Pressure; Diagonal Band of Broca; Dose-Response Relationship, Drug; Glutamic Acid; Heart Rate; Imidazoles; Isoquinolines; Male; Microinjections; Nitrergic Neurons; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 2007 |
Rapid bidirectional switching of synaptic NMDA receptors.
Topics: Aging; Animals; Brain; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Male; Organ Culture Techniques; Piperidines; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2007 |
TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzodiazepines; Binding, Competitive; Cell Line; Cerebellum; Crystallography, X-Ray; Drug Partial Agonism; Hippocampus; Humans; In Vitro Techniques; Interneurons; Mice; Models, Molecular; Patch-Clamp Techniques; Protein Conformation; Protein Subunits; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Structure-Activity Relationship; Synaptic Transmission; Trichlormethiazide | 2007 |
The role of NMDA and non-NMDA receptors in the NTS in mediating three distinct sympathoinhibitory reflexes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Blood Pressure; Cholecystokinin; GABA Agonists; Heart Rate; Kynurenic Acid; Male; Muscimol; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Synaptic Transmission | 2007 |
Different roles for AMPA and NMDA receptors in transmission at the immature retinogeniculate synapse.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Geniculate Bodies; In Vitro Techniques; Magnesium; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Synapses; Visual Pathways | 2008 |
The ventrolateral periaqueductal gray is involved in the cardiovascular response evoked by l-glutamate microinjection into the lateral hypothalamus of anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Cobalt; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypothalamic Area, Lateral; Isoquinolines; Male; Microinjections; Nerve Block; Periaqueductal Gray; Quinoxalines; Rats; Rats, Wistar | 2008 |
Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.
Topics: 4-Aminopyridine; Afferent Pathways; Analysis of Variance; Animals; Catecholamines; Cholecystokinin; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridazines; Quinoxalines; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2007 |
Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: relevance of AMPA receptor-mediated NO signaling.
Topics: Animals; Benzothiadiazines; Cell Line, Tumor; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Isoenzymes; Neuroglia; Nitric Oxide; Pregnenolone; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfotransferases | 2008 |
Propofol enhances both tonic and phasic inhibitory currents in second-order neurons of the solitary tract nucleus (NTS).
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Propofol; Quinoxalines; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Tetrodotoxin | 2008 |
Major components of endogenous neurotransmission underlying the discharge activity of hypoglossal motoneurons in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Decerebrate State; Dogs; Excitatory Amino Acid Antagonists; Hypoglossal Nerve; Ketanserin; Models, Animal; Models, Neurological; Motor Neurons; Quinoxalines; Synaptic Transmission; Tongue | 2008 |
Glutamatergic neurotransmission is not essential for, but plays a modulatory role in, the production of gasping in arterially-perfused adult rat.
Topics: Animals; Glutamic Acid; Kynurenic Acid; Phrenic Nerve; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration Disorders; Respiratory Mechanics; Synaptic Transmission | 2008 |
Release-dependent variations in synaptic latency: a putative code for short- and long-term synaptic dynamics.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Computer Simulation; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Models, Neurological; Neuronal Plasticity; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Synapses; Synaptic Transmission | 2007 |
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Brain; Depression; Disease Models, Animal; Drug Administration Routes; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hindlimb Suspension; Injections, Intraventricular; Lithium Compounds; Mice; Mice, Inbred C57BL; Protein Transport; Quinoxalines; Receptors, AMPA; Swimming; Time Factors | 2008 |
NMDA receptors in the rat VTA: a critical site for social stress to intensify cocaine taking.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Cocaine-Related Disorders; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Self Administration; Social Environment; Stress, Psychological; Ventral Tegmental Area | 2008 |
The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex.
Topics: Animals; Arginine; Benzoates; Blood Pressure; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Fear; Freezing Reaction, Cataleptic; Glutamic Acid; Heart Rate; Imidazoles; Isoquinolines; Male; Nitric Oxide; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2008 |
Cerebellar dysfunction explains the extinction-like abolition of conditioned eyeblinks after NBQX injections in the inferior olive.
Topics: Action Potentials; Analysis of Variance; Animals; Behavior, Animal; Brain Mapping; Cerebellum; Conditioning, Eyelid; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Neural Inhibition; Neurons; Olivary Nucleus; Quinoxalines; Rabbits | 2008 |
Retinocollicular synapse maturation and plasticity are regulated by correlated retinal waves.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Retina; Superior Colliculi; Synapses; Synaptic Transmission; Visual Pathways | 2008 |
Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3.
Topics: Acoustic Stimulation; Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Calcium; Disease Models, Animal; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Hair Cells, Auditory; Hearing Loss, Sensorineural; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Neurons; Quinoxalines; Reflex, Startle; Seizures; Spiral Ganglion | 2008 |
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Topics: Age Factors; Animals; Animals, Newborn; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Valine | 2008 |
Contribution of NMDA and non-NMDA receptors to in vivo glutamate-induced calpain activation in the rat striatum. Relation to neuronal damage.
Topics: Animals; Calpain; Caspase 3; Corpus Striatum; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spectrin | 2008 |
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Animals, Newborn; Dependovirus; Drug Interactions; Excitatory Amino Acid Antagonists; Gene Transfer Techniques; Hippocampus; In Vitro Techniques; Indoles; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sodium Channel Blockers; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 2008 |
Deficiency of neural cell adhesion molecule or its polysialylation modulates pharmacological effects of the AMPA receptor antagonist NBQX.
Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Cell Adhesion Molecules; Pentylenetetrazole; Quinoxalines; Seizures; Sialyltransferases | 2008 |
Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: effects of GYKI 52466 and its novel analogues.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Conflict, Psychological; Data Interpretation, Statistical; Diazepam; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Motor Activity; Neurons; Patch-Clamp Techniques; Piperazines; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Telencephalon | 2008 |
Single-photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision.
Topics: Amacrine Cells; Animals; Dark Adaptation; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Light; Mice; Mice, Inbred C57BL; Neural Inhibition; Patch-Clamp Techniques; Photons; Pyridazines; Quinoxalines; Retina; Retinal Bipolar Cells; Retinal Rod Photoreceptor Cells; Strychnine; Synapses; Synaptic Transmission | 2008 |
Differential contribution of L-, N-, and P/Q-type calcium channels to [Ca2+]i changes evoked by kainate in hippocampal neurons.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Neurons; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Quinoxalines; Rats; Rats, Wistar | 2008 |
Electric fields due to synaptic currents sharpen excitatory transmission.
Topics: Animals; Cells, Cultured; Dendrites; Diffusion; Dipeptides; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Magnesium; Male; Monte Carlo Method; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA; Synapses | 2008 |
NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala.
Topics: Amygdala; Animals; Blotting, Western; Catheterization; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Feeding Behavior; Isoquinolines; Male; Nicotine; Nucleus Accumbens; Patch-Clamp Techniques; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration; Ventral Tegmental Area | 2009 |
Effects of substance P in the amygdala, ventromedial hypothalamus, and periaqueductal gray on fear-potentiated startle.
Topics: Amygdala; Analysis of Variance; Animals; Catheterization; Conditioning, Classical; Fear; Male; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Physalaemin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex, Startle; Substance P; Superior Colliculi; Ventromedial Hypothalamic Nucleus | 2009 |
Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder.
Topics: Acoustic Stimulation; Amantadine; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Riluzole | 2008 |
Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Electroporation; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Patch-Clamp Techniques; Photic Stimulation; Piperazines; Quinoxalines; Retinal Bipolar Cells; Retinal Degeneration; Retinal Ganglion Cells; Rhodopsin; Time Factors; Vision, Ocular; Visual Pathways | 2008 |
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dendritic Spines; Disease Models, Animal; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medial Forebrain Bundle; Mice; Mice, Transgenic; Nerve Net; Neurons; Oxidopamine; Parkinson Disease; Patch-Clamp Techniques; Quinoxalines; Receptors, Dopamine D1; Receptors, Dopamine D2; Sympatholytics; Synapses | 2008 |
Excitatory GABA in rodent developing neocortex in vitro.
Topics: Age Factors; Animals; Animals, Newborn; Bumetanide; Excitatory Amino Acid Antagonists; Female; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Mice; Models, Neurological; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Sodium Potassium Chloride Symporter Inhibitors; Valine | 2008 |
Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences.
Topics: Animals; Animals, Newborn; Dendritic Spines; Dizocilpine Maleate; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; Female; Hypothalamus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Silver Staining | 2008 |
Pharmacologic analysis of the mechanism of dark neuron production in cerebral cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Artifacts; Biopsy; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglycemia; Male; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetraethylammonium | 2008 |
Region-specific involvement of AMPA/Kainate receptors in Fos protein expression induced by cocaine-conditioned cues.
Topics: Animals; Behavior, Animal; Brain Mapping; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Gene Expression Regulation; Male; Oncogene Proteins v-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Self Administration; Time Factors | 2008 |
High-frequency organization and synchrony of activity in the purkinje cell layer of the cerebellum.
Topics: Action Potentials; Anesthesia; Animals; Benzodiazepines; Benzoxazines; Biological Clocks; Cannabinoids; Cerebellum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Models, Neurological; Morpholines; Naphthalenes; Picrotoxin; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Reaction Time | 2008 |
Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1).
Topics: Actin Depolymerizing Factors; Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysics; Cells, Cultured; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; p21-Activated Kinases; Patch-Clamp Techniques; Quinoxalines; Synapses | 2009 |
Microinjection of muscimol into the periaqueductal gray suppresses cardiovascular and neuroendocrine response to air jet stress in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Air; Animals; Blood Pressure; Cardiovascular System; Consciousness; Excitatory Amino Acid Antagonists; GABA Agonists; Heart Rate; Male; Microinjections; Muscimol; Neurosecretory Systems; Periaqueductal Gray; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Physiological | 2008 |
Peripheral AMPA receptors contribute to muscle nociception and c-fos activation.
Topics: Animals; Enzyme Activation; Excitatory Amino Acid Antagonists; Facial Pain; Immunohistochemistry; Male; Masseter Muscle; Mustard Plant; Neurons, Afferent; Plant Oils; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Trigeminal Nucleus, Spinal | 2008 |
Extended fear conditioning reveals a role for both N-methyl-D-aspartic acid and non-N-methyl-D-aspartic acid receptors in the amygdala in the acquisition of conditioned fear.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Combinations; Excitatory Amino Acid Antagonists; Fear; Male; Psychoacoustics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 2008 |
Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures.
Topics: Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Disease Susceptibility; Enzyme Activation; Epilepsy; Excitatory Postsynaptic Potentials; Fructose; Hypoxia; Male; Phosphorylation; Protein Kinase C; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Topiramate | 2008 |
The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy.
Topics: Animals; Dizocilpine Maleate; Foot; Infusions, Parenteral; Male; Models, Animal; Morphine; Narcotics; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Subarachnoid Space | 2008 |
GABAergic circuits control input-spike coupling in the piriform cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Models, Neurological; Nerve Net; Neurons; Olfactory Pathways; Patch-Clamp Techniques; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Triazines | 2008 |
Estradiol replacement modifies c-fos expression at the spinomedullary junction evoked by temporomandibular joint stimulation in ovariectomized female rats.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Estradiol; Estrogens; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Medulla Oblongata; Mustard Plant; Ovariectomy; Plant Oils; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Temporomandibular Joint | 2008 |
Synaptic and cellular properties of the feedforward inhibitory circuit within the input layer of the cerebellar cortex.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Cerebellar Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Models, Neurological; Nerve Fibers; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Synapses; Synaptic Transmission | 2008 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Iodine Isotopes; Male; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Prefrontal Cortex; Protein Binding; Pyramidal Cells; Quinolines; Quinoxalines; Receptors, Neurokinin-3; Substance P; Valine | 2008 |
Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Depressive Disorder; Excitatory Amino Acid Antagonists; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming | 2008 |
Continuous shifts in the active set of spinal interneurons during changes in locomotor speed.
Topics: Action Potentials; Adaptation, Physiological; Animals; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Electronic Data Processing; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Interneurons; Larva; Motor Neurons; Movement; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Periodicity; Quinoxalines; Recruitment, Neurophysiological; Spinal Cord; Swimming; Synaptic Potentials; Valine; Zebrafish | 2008 |
Inflammation regulates functional integration of neurons born in adult brain.
Topics: Analysis of Variance; Animals; Calcium-Binding Proteins; Dendritic Spines; Dose-Response Relationship, Radiation; Ectodysplasins; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Inflammation; Inhibitory Postsynaptic Potentials; Lipopolysaccharides; Lysine; Male; Microfilament Proteins; Microscopy, Confocal; Neurogenesis; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Tetrodotoxin; Time Factors | 2008 |
Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices.
Topics: Animals; Bicuculline; Biophysical Phenomena; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; Immunoprecipitation; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Organometallic Compounds; Patch-Clamp Techniques; Phenanthrolines; Phosphorylation; Protein Subunits; Protein Transport; Protein Tyrosine Phosphatases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Synapses; Tyrosine | 2009 |
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Behavior, Animal; Benzylamines; Biotin; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhibition, Psychological; Lidocaine; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Psychomotor Performance; Quinoxalines; Racemases and Epimerases; Rotarod Performance Test; Space Perception | 2009 |
Presynaptic actions of D2-like receptors in the rat cortico-striato-globus pallidus disynaptic connection in vitro.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Dopamine Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Globus Pallidus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Pathways; Patch-Clamp Techniques; Piperazines; Presynaptic Terminals; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D2; Synapses | 2009 |
Stimulation of NMDA and AMPA glutamate receptors elicits distinct concentration dynamics of nitric oxide in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2009 |
Differential cAMP signaling at hippocampal output synapses.
Topics: Action Potentials; Analysis of Variance; Animals; Calcium; Colforsin; Cyclic AMP; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Isoquinolines; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Kinase Inhibitors; Pyridazines; Quinoxalines; Rats; Signal Transduction; Sulfonamides; Synapses; Time Factors | 2008 |
Agonist occupancy is essential for forward trafficking of AMPA receptors.
Topics: Animals; Binding Sites; Biotinylation; Cell Line, Transformed; Chlorocebus aethiops; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Humans; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Membrane Potentials; Models, Molecular; Patch-Clamp Techniques; Point Mutation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Quinoxalines; Receptors, AMPA; Transfection | 2009 |
Abnormal network activity in a targeted genetic model of human double cortex.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats.
Topics: Animals; Arginine; Baroreflex; Benzoates; Blood Pressure; Cardiac Output; Cholinergic Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Imidazoles; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroprusside; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Tropanes | 2009 |
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase.
Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures | 2009 |
Cardiovascular and thermal responses evoked from the periaqueductal grey require neuronal activity in the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Body Temperature Regulation; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; Heart Rate; Hypothalamus; Male; Motor Activity; Muscimol; N-Methylaspartate; Neural Pathways; Paraventricular Hypothalamic Nucleus; Periaqueductal Gray; Quinoxalines; Rats; Rats, Sprague-Dawley | 2009 |
Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro.
Topics: Aconitine; Afferent Pathways; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bicuculline; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Nicotinic; Strontium; Synapses; Synaptic Transmission; Ventral Tegmental Area | 2009 |
Effects of glutamate receptor activation on NG2-glia in the rat optic nerve.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Antigens; Astrocytes; Axons; Biomarkers; Blotting, Western; Calcium; Calcium Signaling; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Microscopy, Fluorescence; Neural Conduction; Neuroglia; Optic Nerve; Proteoglycans; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Tissue Culture Techniques | 2009 |
N-methyl-D-aspartate receptors in the insular cortex modulate baroreflex in unanesthetized rats.
Topics: Anesthetics; Animals; Antihypertensive Agents; Autonomic Pathways; Baroreflex; Blood Pressure; Bradycardia; Cerebral Cortex; Cobalt; Efferent Pathways; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Isoquinolines; Neurons; Nitroprusside; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2009 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors | 2009 |
Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord.
Topics: Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Bicuculline; Biophysics; Carbodiimides; Chromones; Electric Stimulation; Electroporation; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Antagonists; Glycine Agents; In Vitro Techniques; Mice; Motor Neurons; Neural Inhibition; Neural Pathways; Organic Chemicals; Quinoxalines; Reaction Time; Spectrum Analysis; Spinal Cord; Spinal Nerve Roots; Strychnine; Time Factors | 2009 |
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Vesicles; Temperature; Tetrodotoxin | 2009 |
Horizontal cell feedback regulates calcium currents and intracellular calcium levels in rod photoreceptors of salamander and mouse retina.
Topics: Ambystoma; Aniline Compounds; Animals; Calcium; Calcium Signaling; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feedback; HEPES; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Photic Stimulation; Potassium; Quinoxalines; Retina; Retinal Horizontal Cells; Retinal Rod Photoreceptor Cells; Xanthenes | 2009 |
De-coupling of blood flow and metabolism in the rat brain induced by glutamate.
Topics: Amphetamines; Animals; Autoradiography; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Dizocilpine Maleate; Fluorodeoxyglucose F18; Glucose; Glutamic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2009 |
Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat.
Topics: Amyloid beta-Protein Precursor; Animals; Axonal Transport; Axons; Brain; Brain Injuries; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Intermediate Filaments; Male; Neurons; Photomicrography; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Movement; Cerebral Cortex; Electroporation; Embryo, Mammalian; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Interneurons; K Cl- Cotransporters; LIM-Homeodomain Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Muscimol; Nerve Tissue Proteins; Nifedipine; omega-Conotoxin GVIA; Organ Culture Techniques; Pregnancy; Quinoxalines; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sequence Deletion; Symporters; Transcription Factors; Valine | 2009 |
Cardiovascular responses to microinjections of urocortins into the NTS: role of inotropic glutamate receptors.
Topics: Amphibian Proteins; Aniline Compounds; Animals; Corticotropin-Releasing Hormone; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; Peptide Hormones; Pyrimidines; Quinoxalines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Glutamate; Solitary Nucleus; Sympathetic Nervous System; Urocortins | 2009 |
Reduced expression of the "fast" calcium transporter PMCA2a during homeostatic plasticity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Homeostasis; Neuronal Plasticity; Plasma Membrane Calcium-Transporting ATPases; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synapses | 2009 |
Non-N-methyl-d-aspartate glutamate receptors in the lateral hypothalamus modulate cardiac baroreflex responses in conscious rats.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Cobalt; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Isoquinolines; Male; Microinjections; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tachycardia | 2009 |
Glutamatergic neurotransmission in the procerebrum (olfactory center) of a terrestrial mollusk.
Topics: Action Potentials; Amino Acid Sequence; Animal Structures; Animals; Biological Clocks; Gastropoda; Glutamic Acid; Ibotenic Acid; Molecular Sequence Data; Olfactory Pathways; Phylogeny; Quinoxalines; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Smell; Species Specificity; Synaptic Transmission; Vesicular Glutamate Transport Proteins | 2009 |
Compensatory enhancement of intrinsic spiking upon NKCC1 disruption in neonatal hippocampus.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Benzodiazepines; Biophysics; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; K Cl- Cotransporters; Mice; Mice, Knockout; Nerve Net; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Up-Regulation | 2009 |
Somatic spikes regulate dendritic signaling in small neurons in the absence of backpropagating action potentials.
Topics: Action Potentials; Age Factors; Analysis of Variance; Animals; Benzofurans; Biophysical Phenomena; Calcium; Cerebellum; Dendrites; Electric Stimulation; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Nerve Net; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Glutamate; Signal Transduction; Sodium; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2009 |
Regulation of glutamate transport in developing rat oligodendrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Fibroblast Growth Factors; GABA Antagonists; Gangliosides; Gene Expression Regulation, Developmental; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurons; O Antigens; Oligodendroglia; Patch-Clamp Techniques; Platelet-Derived Growth Factor; Pregnancy; Quinoxalines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Tritium | 2009 |
Odor representations in olfactory cortex: "sparse" coding, global inhibition, and oscillations.
Topics: Action Potentials; Animals; Animals, Newborn; Biological Clocks; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Nerve Net; Neural Inhibition; Neurons; Odorants; Olfactory Pathways; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Time Factors | 2009 |
Oxytocin enhances the inhibitory effects of diazepam in the rat central medial amygdala.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Diazepam; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neural Inhibition; Neurons; Oxytocin; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley | 2010 |
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amlodipine; Amyloid beta-Protein Precursor; Animals; Autoimmune Diseases; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cytokines; Disease Models, Animal; Drug Interactions; Ectodysplasins; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Magnetic Resonance Imaging; Manganese; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neoplasm Proteins; omega-Conotoxin GVIA; Optic Nerve; Optic Neuritis; Quinoxalines; Rats; RNA-Binding Proteins | 2009 |
Effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor blockade on increased cerebral O(2) consumption in Eker rats.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Heart Rate; Hydrogen-Ion Concentration; Male; Oxygen; Oxygen Consumption; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Species Specificity | 2009 |
Munc13-2 differentially affects hippocampal synaptic transmission and plasticity.
Topics: Animals; Animals, Newborn; Calcium; Cyclopropanes; Dipeptides; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Synapses | 2010 |
Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol.
Topics: Animals; Animals, Newborn; Aromatase Inhibitors; Bicuculline; Biophysics; Drug Interactions; Electric Stimulation; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Fulvestrant; GABA Antagonists; In Vitro Techniques; Letrozole; Long-Term Potentiation; Male; Nitriles; Quinoxalines; Rats; Rats, Wistar; Triazoles; Valine; Vestibular Nuclei | 2009 |
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease.
Topics: Age Factors; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Antioxidants; Brain; Cell Count; Cell Survival; Chromatography, High Pressure Liquid; Dopamine; Drosophila; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Immunohistochemistry; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Pentacyclic Triterpenes; Quinoxalines; Triterpenes; Ubiquinone | 2009 |
Context-dependent effects of NMDA receptors on precise timing information at the endbulb of Held in the cochlear nucleus.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Biophysical Phenomena; Biophysics; Cochlear Nerve; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred CBA; Neural Conduction; Neurons; Patch-Clamp Techniques; Piperazines; Probability; Quinoxalines; Reaction Time; Receptors, N-Methyl-D-Aspartate; Synapses; Time Perception | 2009 |
Approach sensitivity in the retina processed by a multifunctional neural circuit.
Topics: Action Potentials; Animals; Biotin; Computer Simulation; Connexins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gap Junction delta-2 Protein; Green Fluorescent Proteins; Luminescent Proteins; Mice; Mice, Transgenic; Models, Neurological; Motion Perception; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurons; Patch-Clamp Techniques; Photic Stimulation; Piperazines; Quinoxalines; Retina; Visual Fields; Visual Pathways | 2009 |
Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Biotin; Cerebral Cortex; Computer Simulation; Electric Stimulation; Electron Transport Complex IV; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Transgenic; Models, Neurological; Neuronal Plasticity; Parvalbumins; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Probability; Quinoxalines; Sensory Deprivation; Synaptic Transmission; Vesicular Glutamate Transport Protein 2; Vibrissae | 2009 |
Selective expression of ligand-gated ion channels in L5 pyramidal cell axons.
Topics: Animals; Animals, Newborn; Axons; Calcium; Calcium Signaling; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Indoles; Ion Channel Gating; Ion Channels; Iontophoresis; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley | 2009 |
GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; CREB-Binding Protein; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Lysine; Membrane Potentials; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Receptors, GABA-B; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2009 |
Excitatory and inhibitory synapses in neuropeptide Y-expressing striatal interneurons.
Topics: Animals; Bicuculline; Biophysical Phenomena; Biophysics; Choline O-Acetyltransferase; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Interneurons; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptide Y; Organophosphonates; Parvalbumins; Patch-Clamp Techniques; Piperazines; Quinoxalines; Sodium Channel Blockers; Synapses; Synaptic Potentials; Tetrodotoxin | 2009 |
Long-term potentiation of excitatory synapses on neocortical somatostatin-expressing interneurons.
Topics: Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Long-Term Potentiation; Mice; Mice, Transgenic; Neocortex; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Somatostatin; Synapses | 2009 |
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Biophysics; CA1 Region, Hippocampal; Cadmium Chloride; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lamotrigine; Lysine; Male; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Tetraethylammonium; Triazines; Valine | 2010 |
Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration.
Topics: Action Potentials; Animals; Animals, Newborn; Biophysics; Cell Line, Transformed; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Humans; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Phosphinic Acids; Photic Stimulation; Piperazines; Propanolamines; Quinoxalines; Rats; Rats, Sprague-Dawley; Rhodopsin; Synapses; Time Factors; Transfection | 2009 |
Development of multisensory convergence in the Xenopus optic tectum.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Age Factors; Amino Acids; Animals; Brain Mapping; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; GABA Antagonists; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Superior Colliculi; Xenopus; Xenopus laevis | 2009 |
IL1RAPL1 controls inhibitory networks during cerebellar development in mice.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Calbindins; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interleukin-1 Receptor-Like 1 Protein; Mice; Mice, Knockout; Neural Inhibition; Neuronal Calcium-Sensor Proteins; Neurons; Neuropeptides; Parvalbumins; Patch-Clamp Techniques; Quinoxalines; Receptors, Interleukin; S100 Calcium Binding Protein G; Tetrodotoxin | 2009 |
Roles of perirhinal and posterior piriform cortices in control and generation of seizures: a microinfusion study in rats exposed to soman.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Electroencephalography; GABA Agonists; Male; Muscarinic Antagonists; Muscimol; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Scopolamine; Seizures; Soman; Statistics, Nonparametric | 2010 |
Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Patch-Clamp Techniques; Posterior Horn Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2009 |
Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Bicarbonates; Energy Metabolism; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Ketone Bodies; Membrane Potentials; Models, Biological; Neocortex; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Pyruvic Acid; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge.
Topics: Amino Acids; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Histamine; Indoles; Ketamine; Limbic System; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2010 |
Neural correlates of variations in event processing during learning in basolateral amygdala.
Topics: Action Potentials; Amygdala; Analysis of Variance; Animals; Choice Behavior; Conditioning, Operant; Dopamine; Excitatory Amino Acid Antagonists; Male; Neurons; Odorants; Quinoxalines; Rats; Rats, Long-Evans; Reward; Statistics as Topic; Ventral Tegmental Area | 2010 |
In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus.
Topics: Animals; CA1 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Electrochemical Techniques; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microelectrodes; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Inactivation of the central but not the basolateral nucleus of the amygdala disrupts learning in response to overexpectation of reward.
Topics: Amygdala; Animals; Association Learning; Attention; Cognition; Cues; Excitatory Amino Acid Antagonists; Glutamic Acid; Learning; Learning Disabilities; Limbic System; Male; Mental Processes; Neural Pathways; Neuropsychological Tests; Quinoxalines; Rats; Rats, Long-Evans; Receptors, Glutamate; Reward; Synaptic Transmission; Teaching | 2010 |
Characterisation of bipolar cell synaptic transmission in goldfish retina using paired recordings.
Topics: Animals; Cell Membrane; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exocytosis; Goldfish; In Vitro Techniques; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Bipolar Cells; Retinal Ganglion Cells; Synaptic Transmission | 2010 |
Effect of hypoxia on expiratory muscle activity in fetal sheep.
Topics: Animals; Diaphragm; Electromyography; Excitatory Amino Acid Antagonists; Fetus; Hypoxia; Injections, Intraventricular; Laryngeal Muscles; Quinoxalines; Receptors, AMPA; Respiratory Mechanics; Respiratory Rate; Sheep | 2010 |
Two modes of release shape the postsynaptic response at the inner hair cell ribbon synapse.
Topics: Animals; Animals, Newborn; Benzothiadiazines; Biophysics; Cochlea; Cochlear Nerve; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hair Cells, Auditory, Inner; Hearing; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses | 2010 |
Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain.
Topics: Age Factors; Analysis of Variance; Animals; Brain; Cell Count; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Quinoxalines; Seizures; Severity of Illness Index; Species Specificity | 2010 |
Effects of pharmacological entopeduncular manipulations on idiopathic dystonia in the dt(sz) mutant hamster.
Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine | 2010 |
N-methyl-D-aspartate glutamate receptors in the hypothalamic paraventricular nucleus modulate cardiac component of the baroreflex in unanesthetized rats.
Topics: Adrenergic beta-Antagonists; Animals; Baroreflex; Blood Pressure; Bradycardia; Cobalt; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Isoquinolines; Male; Microinjections; Parasympathetic Nervous System; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2010 |
Postnatal switch from synaptic to extrasynaptic transmission between interneurons and NG2 cells.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Calcium; Cell Line, Transformed; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Luminescent Proteins; Lysine; Mice; Mice, Transgenic; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oligodendroglia; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Pyridazines; Pyridines; Quinoxalines; Statistics, Nonparametric; Stem Cells; Synapses; Synaptic Transmission | 2010 |
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.
Topics: Animals; Calcium-Binding Proteins; Calpain; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Gene Expression; Kainic Acid; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Phosphoproteins; Plasma Membrane Calcium-Transporting ATPases; Proteome; Proteomics; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; RNA, Small Interfering; Spinal Cord | 2010 |
Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Axons; Biophysical Phenomena; Brain; Cadmium Chloride; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Models, Neurological; Motor Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetraethylammonium | 2010 |
NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats.
Topics: Acoustic Stimulation; Amygdala; Animals; Auditory Perception; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Memory; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Granule cells in the CA3 area.
Topics: Animals; Animals, Newborn; CA3 Region, Hippocampal; Calbindins; Cannabinoid Receptor Modulators; Cholecystokinin; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Homeodomain Proteins; In Vitro Techniques; Lysine; Membrane Potentials; Microscopy, Electron, Transmission; Nerve Net; Neurons; Neuropeptide Y; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Synapses; Tumor Suppressor Proteins | 2010 |
Correlated firing in tufted cells of mouse olfactory bulb.
Topics: Action Potentials; Animals; Dendrites; Excitatory Amino Acid Antagonists; Gap Junctions; Male; Mice; Neurons; Olfactory Bulb; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA; Smell | 2010 |
Metaplasticity at single glutamatergic synapses.
Topics: Anesthetics, Local; Animals; Biophysics; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetanus Toxin; Tetrodotoxin; Time Factors; Transfection; Valine | 2010 |
Glutamate enhances the surface distribution and release of Munc18 in cerebral cortical neurons.
Topics: Animals; Biotinylation; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; L-Lactate Dehydrogenase; Munc18 Proteins; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
AMPA receptor mediates mGlu 2/3 receptor antagonist-induced dopamine release in the rat nucleus accumbens shell.
Topics: Amino Acids; Animals; Dioxoles; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microdialysis; Nucleus Accumbens; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Xanthenes | 2010 |
Intralaminar and interlaminar activity within the rodent superior colliculus visualized with voltage imaging.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthetics, Local; Animals; Bicuculline; Biophysical Phenomena; Brain Mapping; Diagnostic Imaging; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Neural Conduction; Neural Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Superior Colliculi; Synapses; Tetrodotoxin | 2010 |
Tetrodotoxin-resistant sodium channels contribute to directional responses in starburst amacrine cells.
Topics: Amacrine Cells; Animals; Electric Conductivity; Motion; Quinoxalines; Rabbits; Sodium Channel Blockers; Sodium Channels; Synapses; Tetrodotoxin | 2010 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citric Acid; Cough; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mechanoreceptors; Propionates; Quinoxalines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Recurrent Laryngeal Nerve; Reflex; Respiratory Mucosa; Sensory Receptor Cells; Solitary Nucleus; Substance P; Trachea; Vagus Nerve; Valine | 2011 |
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex | 2011 |
The bed nucleus of the stria terminalis is required for the expression of contextual but not auditory freezing in rats with basolateral amygdala lesions.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Conditioning, Classical; Cues; Electroshock; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Septal Nuclei | 2011 |
Behavioral activating effects of selective AMPA receptor antagonism in the ventral tegmental area.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Reinforcement Schedule; Self Administration; Ventral Tegmental Area | 2010 |
Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biological Clocks; Brain Stem; Cadmium Chloride; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Glycyrrhetinic Acid; Humans; In Vitro Techniques; Larva; Models, Biological; Movement; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Periodicity; Pyridazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming; Xenopus | 2010 |
Ethanol affects striatal interneurons directly and projection neurons through a reduction in cholinergic tone.
Topics: Animals; Barium; Biophysics; Central Nervous System Depressants; Cholinergic Agents; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ethanol; Excitatory Amino Acid Antagonists; Female; Interneurons; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2011 |
Pre- and post-synaptic functions of kainate receptors at glutamate and GABA synapses in the rat entorhinal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Entorhinal Cortex; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nerve Net; Neural Inhibition; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission | 2012 |
Sensory modality-specific homeostatic plasticity in the developing optic tectum.
Topics: Animals; Biophysics; Dark Adaptation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; GABA Antagonists; Homeostasis; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Physical Stimulation; Picrotoxin; Quinoxalines; Sensory Deprivation; Superior Colliculi; Xenopus laevis | 2011 |
Glutamate-vasopressin interactions and the neurobiology of anabolic steroid-induced offensive aggression.
Topics: Age Factors; Aggression; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anabolic Agents; Animals; Animals, Newborn; Arginine Vasopressin; Behavior, Animal; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hormone Antagonists; Hypothalamic Area, Lateral; Male; Mesocricetus; Microinjections; Quinoxalines; Septal Nuclei; Statistics, Nonparametric; Steroids; Vasopressins; Vesicular Glutamate Transport Protein 2 | 2011 |
Glutamatergic pre-ictal discharges emerge at the transition to seizure in human epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Biophysics; Brain Mapping; Confidence Intervals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; Nerve Net; Potassium Chloride; Quinoxalines; Valine; Young Adult | 2011 |
Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice.
Topics: Animals; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Confocal; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Retina; Retinal Degeneration; Retinal Ganglion Cells; Sesterterpenes; Strychnine; Visual Pathways | 2011 |
Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Calcium Signaling; Cerebellum; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Membrane Microdomains; Neural Pathways; Nickel; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Phosphinic Acids; Piperidines; Presynaptic Terminals; Propanolamines; Purkinje Cells; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spider Venoms; Tetrodotoxin; Xanthines | 2011 |
Excitation-inhibition balance in the CA3 network--neuronal specificity and activity-dependent plasticity.
Topics: Animals; CA3 Region, Hippocampal; Convulsants; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Kindling, Neurologic; Male; Nerve Net; Neuronal Plasticity; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Seizures; Synaptic Transmission; Valine | 2011 |
mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Electric Stimulation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Knockout; Models, Biological; N-Methylaspartate; Piperidines; Pyramidal Cells; Pyridines; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thiazoles; Time Factors; Visual Cortex | 2011 |
A positive feedback synapse from retinal horizontal cells to cone photoreceptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Calcium; Calcium Signaling; Feedback, Physiological; Glutamic Acid; In Vitro Techniques; Lizards; Membrane Potentials; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Synapses; Zebrafish | 2011 |
Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.
Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Lethal Dose 50; Levetiracetam; Male; Motor Activity; Muscimol; Nicotinic Antagonists; Piracetam; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors | 2011 |
mGluR1, but not mGluR5, activates feed-forward inhibition in the medial prefrontal cortex to impair decision making.
Topics: Animals; Biofeedback, Psychology; Decision Making; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Neural Inhibition; Organ Culture Techniques; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2011 |
Desynchronization of multivesicular release enhances Purkinje cell output.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Biophysical Phenomena; Calcium; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Linear Models; Mice; Nerve Fibers; Nerve Net; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Strontium; Synapses; Time Factors | 2011 |
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Helplessness, Learned; Hindlimb Suspension; Ketamine; Male; Mice; Mice, Inbred ICR; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors | 2011 |
Accumbens shell AMPA receptors mediate expression of extinguished reward seeking through interactions with basolateral amygdala.
Topics: Amygdala; Animals; Baclofen; Conditioning, Operant; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Extinction, Psychological; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Muscimol; Nucleus Accumbens; Quinoxalines; Rats; Receptors, AMPA; Reward; Self Administration | 2011 |
Cannabinoids modulate spontaneous synaptic activity in retinal ganglion cells.
Topics: Animals; Animals, Newborn; Benzoxazines; Biophysics; Cannabinoids; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retina; Retinal Ganglion Cells; Space Perception | 2011 |
Combined LTP and LTD of modulatory inputs controls neuronal processing of primary sensory inputs.
Topics: Animals; Biophysics; Cochlear Nerve; Cochlear Nucleus; Computer Simulation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Models, Neurological; Patch-Clamp Techniques; Quinoxalines; Reaction Time; Sensory Receptor Cells; Synapses | 2011 |
Axon-glia synapses are highly vulnerable to white matter injury in the developing brain.
Topics: Animals; Animals, Newborn; Antigens; Brain Injuries; Carotid Artery Diseases; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Glial Fibrillary Acidic Protein; Hypoxia-Ischemia, Brain; Leukoencephalopathies; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Minocycline; Myelin Basic Protein; Nerve Fibers, Myelinated; Neuroglia; Polysaccharides; Proteoglycans; Quinoxalines; Receptors, AMPA; Synapses; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2012 |
GABA(B) restrains release from singly-evoked GABA terminals.
Topics: Analysis of Variance; Animals; Benzylamines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Phosphinic Acids; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Sodium Channel Blockers; Solitary Nucleus; Synapses; Tetrodotoxin; Valine | 2011 |
A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα.
Topics: Analysis of Variance; Animals; ARNTL Transcription Factors; Bicuculline; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Circadian Clocks; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dendrites; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; GTPase-Activating Proteins; Hippocampus; Humans; Immunoprecipitation; Leupeptins; Mice; Mice, Knockout; Mutation; Neurons; Nuclear Proteins; Nuclear Receptor Subfamily 1, Group D, Member 1; Quinoxalines; Rats; RNA, Messenger; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Transfection; Two-Hybrid System Techniques; Valine | 2011 |
Cellular mechanisms of desynchronizing effects of hypothermia in an in vitro epilepsy model.
Topics: Action Potentials; Aminoquinolines; Animals; Animals, Newborn; Bicuculline; Biophysics; Cerebral Cortex; Convulsants; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; Hypothermia, Induced; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Phorbol Esters; Quinaldines; Quinoxalines; Sodium Channel Blockers; Strychnine; Temperature; Tetrodotoxin | 2012 |
Acute administration of AMPA/Kainate blocker combined with delayed transplantation of neural precursors improves lower urinary tract function in spinal injured rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Diagnostic Imaging; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Flow Cytometry; Motor Activity; Neural Stem Cells; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Recovery of Function; Serotonin; Spinal Injuries; Urinary Bladder Diseases; Urination; Urodynamics | 2011 |
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.
Topics: Animals; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Mice; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2011 |
Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Calcium Channels; Cell Line; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Quinoxalines; Receptors, AMPA | 2011 |
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche.
Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Biophysical Phenomena; Cell Adhesion Molecules, Neuronal; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Matrix Proteins; GABA Antagonists; Glutamic Acid; Green Fluorescent Proteins; Interneurons; Iontophoresis; Luminescent Proteins; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurogenesis; Neuropeptide Y; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Picrotoxin; Pro-Opiomelanocortin; Quinoxalines; Reelin Protein; Serine Endopeptidases; Stem Cell Niche; Synaptic Potentials; Time Factors; Valine | 2011 |
Spatiotemporal analysis of electrically evoked activity in the chicken optic tectum: a VSDI study.
Topics: Animals; Animals, Newborn; Bicuculline; Brain Mapping; Calcium; Chickens; Electric Stimulation; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Quinoxalines; Superior Colliculi; Time Factors; Visual Pathways; Voltage-Sensitive Dye Imaging | 2012 |
Light-evoked lateral GABAergic inhibition at single bipolar cell synaptic terminals is driven by distinct retinal microcircuits.
Topics: Analysis of Variance; Animals; Carboxylic Acids; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; Female; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Light; Male; Neural Inhibition; Patch-Clamp Techniques; Pertussis Toxin; Photic Stimulation; Photoreceptor Cells; Presynaptic Terminals; Propionates; Pyridazines; Quinoxalines; Retina; Retinal Bipolar Cells; Signal Transduction; Sodium Channel Blockers; Statistics, Nonparametric; Tetrodotoxin | 2011 |
Glutamate spillover promotes the generation of NMDA spikes.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Biophysics; Calcium; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Drug Synergism; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Indoles; Male; Mice; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Statistics, Nonparametric | 2011 |
Glucose starvation stimulates Zn2+ toxicity in cultures of cerebellar granule neurons.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cerebellum; Chlorides; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Ruthenium Red; Zinc Compounds | 2012 |
System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo.
Topics: Animals; Cystine; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Gene Expression Regulation; Glutamic Acid; Glutathione; Laser Capture Microdissection; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Quinoxalines; Spinal Cord Diseases | 2012 |
Synaptic transmission changes in fear memory circuits underlie key features of an animal model of schizophrenia.
Topics: Action Potentials; Amygdala; Animals; Area Under Curve; Biophysics; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Male; Memory Disorders; Neurons; Parvalbumins; Patch-Clamp Techniques; Phencyclidine; Quinoxalines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Schizophrenia; Synaptic Transmission; Time Factors | 2012 |
NMDA receptor agonists fail to alter release from cerebellar basket cells.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Biophysics; Calcium; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Indoles; Inhibitory Postsynaptic Potentials; Interneurons; Iontophoresis; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
Influence of sex and estrous cycle on synaptic responses of the medial vestibular nuclei in rats: role of circulating 17β-estradiol.
Topics: Analysis of Variance; Androgens; Animals; Electric Stimulation; Estradiol; Estrogens; Estrous Cycle; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Long-Term Potentiation; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Sex Characteristics; Synapses; Testosterone; Valine; Vestibular Nuclei | 2012 |
The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling.
Topics: Animals; Antidepressive Agents; Benzhydryl Compounds; CHO Cells; Conditioning, Operant; Cricetinae; Cricetulus; Cyclic AMP; Glutamic Acid; Hindlimb Suspension; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Signal Transduction | 2012 |
Parallel regulation of feedforward inhibition and excitation during whisker map plasticity.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysical Phenomena; Biophysics; Brain Mapping; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Nerve Net; Neural Inhibition; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Long-Evans; Sensory Deprivation; Somatosensory Cortex; Time Factors; Vibrissae | 2011 |
Glutamate receptor subunit GluA1 is necessary for long-term potentiation and synapse unsilencing, but not long-term depression in mouse hippocampus.
Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Knockout; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain Ischemia; CA1 Region, Hippocampal; Diazepam; Disease Models, Animal; Drug Delivery Systems; Gerbillinae; Glutathione Transferase; Intramolecular Oxidoreductases; Lipocalins; Male; Mice; Pyramidal Cells; Quinoxalines; Recombinant Fusion Proteins; Solubility; Water | 2012 |
Sphingomyelinase selectively reduces M1 muscarinic receptors in rat hippocampal membranes.
Topics: Animals; Arrestins; beta-Arrestins; Bicuculline; Biotinylation; Cell Membrane; Drug Interactions; Excitatory Amino Acid Antagonists; G-Protein-Coupled Receptor Kinase 2; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Muscarinic Agonists; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sphingomyelin Phosphodiesterase; Time Factors; Valine | 2012 |
What a nostril knows: olfactory nerve-evoked AMPA responses increase while NMDA responses decrease at 24-h post-training for lateralized odor preference memory in neonate rat.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Conditioning, Psychological; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Functional Laterality; In Vitro Techniques; Learning; Male; N-Methylaspartate; Nose; Odorants; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell; Tetrodotoxin | 2012 |
Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity.
Topics: Animals; Animals, Newborn; Bacterial Proteins; Biophysics; Cerebral Cortex; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperazines; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Thy-1 Antigens; Transfection | 2012 |
Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Bradykinin; Cats; Data Interpretation, Statistical; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Heart; Kidney; Male; Microinjections; Neurons, Afferent; Pons; Quinoxalines; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Sympathetic Nervous System; Vagotomy | 2012 |
Evoked axonal oxytocin release in the central amygdala attenuates fear response.
Topics: Action Potentials; Amygdala; Analysis of Variance; Animals; Axons; Behavior, Animal; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Fear; Female; Fiber Optic Technology; GABA Antagonists; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Inhibition, Psychological; Lactation; Light; Microscopy, Electron, Transmission; Models, Biological; Neurons; Oxytocin; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Picrotoxin; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Rhodopsin; Time Factors; Vasotocin; Vesicular Glutamate Transport Protein 2 | 2012 |
AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test.
Topics: Acetylcysteine; alpha-Methyltyrosine; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fenclonine; Hindlimb Suspension; Locomotion; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Receptors, AMPA | 2012 |
Ionotropic glutamate receptors in hypothalamic paraventricular and supraoptic nuclei mediate vasopressin and oxytocin release in unanesthetized rats.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; N-Methylaspartate; Oxytocin; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Vasopressins | 2012 |
Distinct neuronal coding schemes in memory revealed by selective erasure of fast synchronous synaptic transmission.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Conditioning, Psychological; Electric Stimulation; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Fear; Hippocampus; Memory; Mice; Mice, Inbred C57BL; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Synaptic Transmission; Synaptotagmin I; Transduction, Genetic | 2012 |
Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Infusions, Intraventricular; Levodopa; Male; Oxidopamine; Phenols; Piperidines; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus; Thiazoles | 2012 |
Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury.
Topics: Analysis of Variance; Animals; Apoptosis; Cervical Vertebrae; Excitatory Amino Acid Antagonists; Female; Fructose; Grooming; Histological Techniques; Movement; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Long-Evans; Spinal Cord Injuries; Topiramate | 2012 |
GABAergic inhibition regulates developmental synapse elimination in the cerebellum.
Topics: Agatoxins; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Biophysical Phenomena; Biophysics; Calbindins; Calcium; Calcium Channels; Cerebellum; Chromones; Cytochromes c; Dendrites; Diazepam; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurotoxins; Patch-Clamp Techniques; Phospholipase C beta; Protein Kinase C; Purkinje Cells; Quinoxalines; Receptors, Glutamate; Receptors, Metabotropic Glutamate; S100 Calcium Binding Protein G; Synapses; Vesicular Inhibitory Amino Acid Transport Proteins | 2012 |
Effects of cue-triggered expectation on cortical processing of taste.
Topics: Acoustic Stimulation; Action Potentials; Afferent Pathways; Amygdala; Analysis of Variance; Animals; Biophysics; Conditioning, Operant; Cues; Discrimination, Psychological; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Motivation; Mouth; Neurons; Parietal Lobe; Quinoxalines; Rats; Rats, Long-Evans; Reaction Time; Sensory System Agents; Statistics as Topic; Taste; Time Factors | 2012 |
Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin.
Topics: Animals; Animals, Newborn; Avoidance Learning; Basal Ganglia; Biophysics; Channelrhodopsins; Cholera Toxin; Conditioning, Operant; Dopamine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate Decarboxylase; Habenula; Humans; In Vitro Techniques; Light; Luminescent Proteins; Membrane Potentials; Nerve Tissue Proteins; Neural Pathways; Neurons; Optics and Photonics; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Transduction, Genetic; Vesicular Glutamate Transport Protein 2 | 2012 |
AMPA receptor-dependent, light-evoked D-serine release acts on retinal ganglion cell NMDA receptors.
Topics: Animals; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Photic Stimulation; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Serine | 2012 |
MPTP modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Biophysics; Dopamine Antagonists; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Receptors, Dopamine; Sodium Channel Blockers; Sulpiride; Tetrodotoxin; Time Factors; Valine | 2012 |
Glissandi: transient fast electrocorticographic oscillations of steadily increasing frequency, explained by temporally increasing gap junction conductance.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adult; Animals; Axons; Computer Simulation; Cortical Synchronization; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gap Junctions; Humans; In Vitro Techniques; Male; Middle Aged; Models, Neurological; Neocortex; Nerve Net; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Reaction Time | 2012 |
Glycine exerts dual roles in ischemic injury through distinct mechanisms.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Dose-Response Relationship, Drug; Glucose; Glycine; Hippocampus; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Viruses | 2012 |
The functional role of ascending nociceptive control in defensive behavior.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Immobility Response, Tonic; Male; Motor Activity; Neural Pathways; Nociception; Nucleus Accumbens; Pain; Quinoxalines; Rats; Rats, Wistar; Somatostatin | 2012 |
Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Brain Stem; Chick Embryo; Cochlea; Coturnix; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Functional Laterality; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; In Vitro Techniques; Kv1.3 Potassium Channel; Lentivirus; Male; Membrane Potentials; Microtubule-Associated Proteins; Models, Animal; Neural Pathways; Neurons; Okadaic Acid; Patch-Clamp Techniques; Picrotoxin; Pyrans; Quinoxalines; Selective Serotonin Reuptake Inhibitors; Synapsins; Transgenes; Valine | 2013 |
D1 receptor modulation of action potential firing in a subpopulation of layer 5 pyramidal neurons in the prefrontal cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Biophysics; Dopamine Antagonists; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Patch-Clamp Techniques; Piperazines; Plant Lectins; Prefrontal Cortex; Pyramidal Cells; Pyridazines; Quinoxalines; Receptors, Dopamine D1; Signal Transduction | 2012 |
Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in stargazer mice.
Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium Channels; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glutamates; In Vitro Techniques; Indoles; Male; Mice; Mice, Mutant Strains; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synapses; Thalamic Nuclei; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Muscarinic control of AMPA receptor responsiveness in mouse spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarinic Agonists; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, Muscarinic; Spinal Cord | 2012 |
Taste aversion memory reconsolidation is independent of its retrieval.
Topics: Amygdala; Animals; Avoidance Learning; Conditioning, Classical; Excitatory Amino Acid Antagonists; Male; Memory; Microinjections; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Taste | 2012 |
Paired-pulse plasticity in the strength and latency of light-evoked lateral inhibition to retinal bipolar cell terminals.
Topics: Anesthetics, Local; Animals; Axotomy; Biophysical Phenomena; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Goldfish; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Light; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Phosphinic Acids; Photons; Presynaptic Terminals; Pyridazines; Pyridines; Quinoxalines; Reaction Time; Retina; Retinal Bipolar Cells; Tetrodotoxin; Time Factors | 2012 |
TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury.
Topics: Age Factors; Animals; Calcium; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; Female; Isoquinolines; Kainic Acid; Motor Neurons; Neurofilament Proteins; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons.
Topics: Amygdala; Animals; Biotinylation; Brain; Cell Death; Cell Survival; Cerebral Cortex; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Membrane Proteins; Mitochondria; Models, Biological; Neurons; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Surface Properties; Tetrazolium Salts; Thiazoles; Zinc | 2012 |
TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory.
Topics: Analysis of Variance; Animals; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cyclin-Dependent Kinase 5; Dendritic Spines; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Guanylate Kinases; Humans; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Maze Learning; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Quinoxalines; rac1 GTP-Binding Protein; Rats; Receptor, trkB; Ribosomal Protein S6 Kinases; Serine; Silver Staining; Spatial Behavior; Synaptophysin; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Time Factors; Transfection | 2012 |
A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Cell Adhesion Molecules, Neuronal; Cell Line, Transformed; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Long-Term Potentiation; Membrane Proteins; MicroRNAs; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Structure, Tertiary; Quinoxalines; Rats; RNA Interference; Statistics, Nonparametric; Stereotaxic Techniques; Transduction, Genetic; Transfection | 2012 |
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.
Topics: A Kinase Anchor Proteins; Action Potentials; Analysis of Variance; Animals; Biophysics; Calcineurin; Calcium; Cells, Cultured; Dendritic Spines; Disks Large Homolog 4 Protein; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guanylate Kinases; Hippocampus; Immunoprecipitation; In Vitro Techniques; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Phosphorylation; Quinoxalines; Receptors, AMPA; Serine; Silver Staining; Sodium Channel Blockers; Subcellular Fractions; Synapses; Tetrodotoxin | 2012 |
Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Corpus Striatum; Dopamine Antagonists; Electric Stimulation; Ethanol; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Food Preferences; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Sucrose; Sulpiride; Sweetening Agents; Synaptosomes; Up-Regulation | 2012 |
Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.
Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2012 |
Paraventricular nucleus of the hypothalamus glutamate neurotransmission modulates autonomic, neuroendocrine and behavioral responses to acute restraint stress in rats.
Topics: Animals; Arterial Pressure; Corticosterone; Excitatory Amino Acid Antagonists; Heart Rate; Isoquinolines; Male; Maze Learning; Microinjections; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Skin Temperature; Stress, Psychological; Synaptic Transmission | 2013 |
Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTD.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Cerebellum; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Purkinje Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 2013 |
Overinhibition of corticostriatal activity following prenatal cocaine exposure.
Topics: Age Factors; Analysis of Variance; Anesthetics, Local; Animals; Biophysics; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Female; GABA Agents; Green Fluorescent Proteins; Hindlimb Suspension; In Vitro Techniques; Interneurons; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Quinoxalines; Quinpirole; Receptors, GABA-A; Rotarod Performance Test; Sodium Channel Blockers; Statistics, Nonparametric; Tetrodotoxin | 2013 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Modulation of extracellular d-serine content by calcium permeable AMPA receptors in rat medial prefrontal cortex as revealed by in vivo microdialysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Area Under Curve; Benzothiadiazines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Extracellular Fluid; Fluorometry; Gas Chromatography-Mass Spectrometry; Male; Microdialysis; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Serine; Spermine; Time Factors | 2013 |
Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Blood Pressure; Cardiovascular System; Denervation; Excitatory Amino Acid Antagonists; Heart Rate; Male; Melanocyte-Stimulating Hormones; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptors, Corticotropin; Splanchnic Nerves; Sympathetic Nervous System | 2012 |
NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus.
Topics: Animals; Behavior, Animal; Bicuculline; Excitatory Amino Acid Antagonists; Fear; GABA-A Receptor Antagonists; Hypothalamus, Middle; Isoquinolines; Male; Nociceptive Pain; Pain Perception; Panic; Prefrontal Cortex; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2014 |
Reconstitution of homomeric GluA2(flop) receptors in supported lipid membranes: functional and structural properties.
Topics: Animals; Benzothiadiazines; Glutamic Acid; Ion Channel Gating; Lipid Bilayers; Lipids; Liposomes; Membrane Potentials; Microscopy, Atomic Force; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA | 2013 |
Spike-driven glutamate electrodiffusion triggers synaptic potentiation via a homer-dependent mGluR-NMDAR link.
Topics: Action Potentials; Animals; Animals, Newborn; Aspartic Acid; Biophysics; Carrier Proteins; Cerebellum; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Homer Scaffolding Proteins; Humans; In Vitro Techniques; Luminescent Proteins; Microscopy, Electron, Transmission; Models, Neurological; Monte Carlo Method; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Red Fluorescent Protein; RNA, Small Interfering; Statistics, Nonparametric; Synapses; Synapsins; Transfection | 2013 |
LTP requires a unique postsynaptic SNARE fusion machinery.
Topics: Animals; Animals, Newborn; Biophysics; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Exocytosis; Gene Transfer Techniques; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Membrane Fusion; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Protein Binding; Qa-SNARE Proteins; Quinoxalines; Receptors, AMPA; Receptors, Transferrin; SNARE Proteins; Syntaxin 1; Vesicle-Associated Membrane Protein 2; Vesicular Transport Proteins | 2013 |
TRPC3 channel underlies cerebellar long-term depression.
Topics: Animals; Animals, Newborn; Antibodies; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Long-Term Synaptic Depression; Male; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; TRPC Cation Channels | 2013 |
Physiological release of endogenous tau is stimulated by neuronal activity.
Topics: Action Potentials; Animals; Cells, Cultured; Cerebral Cortex; Neurons; Potassium; Primary Cell Culture; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; tau Proteins | 2013 |
Presynaptic kainate receptor-mediated facilitation of glutamate release involves Ca2+-calmodulin and PKA in cerebrocortical synaptosomes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzodiazepines; Calcium; Calmodulin; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoquinolines; Kainic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Presynaptic; Sulfonamides; Synaptic Transmission; Synaptosomes; Thionucleotides | 2013 |
Hippocampal excitability is increased in aged mice.
Topics: Action Potentials; Age Factors; Aging; Animals; Biophysics; Brain Waves; Diazepam; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Quinoxalines; Wakefulness | 2013 |
NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice.
Topics: Animals; Antidepressive Agents; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Drug Administration Schedule; Drug Interactions; Eating; Excitatory Amino Acid Antagonists; Food Preferences; Immobility Response, Tonic; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ketamine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Motor Activity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2013 |
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Channelrhodopsins; Corpus Striatum; Corticosterone; Disease Models, Animal; DNA Breaks, Double-Stranded; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photic Stimulation; Quinoxalines; Reactive Oxygen Species; Stress, Physiological; tau Proteins; Valine | 2013 |
Novel GABAergic circuits mediating excitation/inhibition of Cajal-Retzius cells in the developing hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Interneurons; Light; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Optogenetics; Patch-Clamp Techniques; Proteins; Pyridazines; Quinoxalines; Receptors, CXCR4; RNA, Untranslated; Sodium Channel Blockers; Somatostatin; Synaptic Potentials; Tetrodotoxin; Valine | 2013 |
Exposure to cocaine regulates inhibitory synaptic transmission in the nucleus accumbens.
Topics: Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Self Administration; Synapses; Tetrodotoxin; Time Factors; Valine | 2013 |
Dopamine triggers heterosynaptic plasticity.
Topics: Analysis of Variance; Animals; Benzoates; Channelrhodopsins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; GABAergic Neurons; Genetic Vectors; Glycine; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Synaptic Depression; Male; Nucleus Accumbens; Optogenetics; Phosphinic Acids; Photic Stimulation; Propanolamines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2013 |
Comparative analysis of changes in membrane currents in neurons and astrocytes in rat hippocampal slices after stimulation of glutamatergic transmission.
Topics: Animals; Astrocytes; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Ouabain; Patch-Clamp Techniques; Potassium; Quinoxalines; Rats; Receptors, Glutamate; Synaptic Transmission | 2013 |
EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.
Topics: Animals; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kainic Acid; KATP Channels; Male; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Probability; Protein Binding; Quinoxalines; Synaptosomes; Transduction, Genetic | 2013 |
Transmission of the respiratory rhythm to trigeminal and hypoglossal motor neurons in the American Bullfrog (Lithobates catesbeiana).
Topics: Action Potentials; Animals; Brain Stem; Choline O-Acetyltransferase; Excitatory Amino Acid Antagonists; Fluoresceins; Hypoglossal Nerve; In Vitro Techniques; Magnesium; Motor Neurons; Physical Stimulation; Quinoxalines; Rana catesbeiana; Respiratory Mechanics; Trigeminal Nerve; Valine | 2013 |
Inhibition of inhibition in visual cortex: the logic of connections between molecularly distinct interneurons.
Topics: Animals; Biomarkers; Channelrhodopsins; Female; Genes, Reporter; Inhibitory Postsynaptic Potentials; Interneurons; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neural Inhibition; Optogenetics; Organophosphorus Compounds; Parvalbumins; Patch-Clamp Techniques; Photic Stimulation; Principal Component Analysis; Pyramidal Cells; Quinoxalines; Recombinant Fusion Proteins; Somatostatin; Synaptic Transmission; Vasoactive Intestinal Peptide; Visual Cortex | 2013 |
Role of bed nucleus of the stria terminalis and amygdala AMPA receptors in the development and expression of context conditioning and sensitization of startle by prior shock.
Topics: Amygdala; Animals; Conditioning, Classical; Electric Stimulation; Fear; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reflex, Startle; Septal Nuclei | 2014 |
Bidirectional modulatory effect of 17β-estradiol on NMDA receptors via ERα and ERβ in the dentate gyrus of juvenile male rats.
Topics: Animals; Dentate Gyrus; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Excitatory Postsynaptic Potentials; Female; Ginsenosides; In Vitro Techniques; Male; NAD; Phenols; Piperazines; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sapogenins | 2013 |
Object-in-place associative recognition memory depends on glutamate receptor neurotransmission within two defined hippocampal-cortical circuits: a critical role for AMPA and NMDA receptors in the hippocampus, perirhinal, and prefrontal cortices.
Topics: Animals; Association Learning; Catheters, Indwelling; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hippocampus; Male; Neural Pathways; Neuronal Plasticity; Neuropsychological Tests; Prefrontal Cortex; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Temporal Lobe | 2015 |
Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Biological Clocks; CA1 Region, Hippocampal; Cholinergic Agents; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Muscarine; Nickel; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Pyrimidines; Quinoxalines; Sodium Channel Blockers; Sodium Channels; Valine | 2013 |
Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis.
Topics: Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hypoxia; Neurogenesis; Neurons; Oligodendroglia; Organ Specificity; Quinoxalines; Rats; Seizures; Time Factors; TOR Serine-Threonine Kinases; Wnt Signaling Pathway | 2013 |
AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures.
Topics: Aging; Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Hippocampus; Male; Neurons; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Seizures | 2013 |
Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; CA1 Region, Hippocampal; Dentate Gyrus; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Quinoxalines; Synaptic Transmission | 2014 |
AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Behavior, Animal; Cartilage, Articular; Excitatory Amino Acid Antagonists; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Knee Joint; Male; Menisci, Tibial; Osteoarthritis; Osteoblasts; Pain; Quinoxalines; Radiography; Rats; Receptors, AMPA; Receptors, Kainic Acid; Synovial Membrane | 2015 |
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Citalopram; Cyclopropanes; Imipramine; Immobility Response, Tonic; Male; Mice; Milnacipran; Morpholines; Motor Activity; N-Methylaspartate; Oxazines; Quinoxalines; Reboxetine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2013 |
Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro.
Topics: Animals; Carbazoles; Chelating Agents; Circadian Clocks; Copper; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Inbred C57BL; Molybdenum; Phenanthrolines; Quinoxalines; Suprachiasmatic Nucleus; Valine | 2014 |
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Glycogen; Hydrogen-Ion Concentration; Hypoglycemia; Kynurenic Acid; Lactic Acid; Leukoencephalopathies; Mice; Mice, Inbred C57BL; Optic Nerve Injuries; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2014 |
Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Embryo, Mammalian; Energy Transfer; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Sodium Channel Blockers; Tetrodotoxin | 2013 |
Inhibition of NADPH oxidase activation in oligodendrocytes reduces cytotoxicity following trauma.
Topics: Acetophenones; Animals; Animals, Newborn; Astrocytes; Axons; Cell Death; Culture Media, Conditioned; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Locomotion; Membrane Glycoproteins; Mice; NADPH Oxidase 2; NADPH Oxidases; Oligodendroglia; Oxidative Stress; Primary Cell Culture; Quinoxalines; Receptors, AMPA; Spinal Cord Injuries | 2013 |
Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.
Topics: Animals; Animals, Newborn; Cerebellum; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Humans; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Psychomotor Performance; Quinoxalines; Reaction Time; Recognition, Psychology; Sodium Channel Blockers; Tetrodotoxin; Valine | 2014 |
Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Dioxoles; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Piperidines; Prefrontal Cortex; Quinoxalines; Rats; Receptors, AMPA; TOR Serine-Threonine Kinases; Up-Regulation | 2014 |
A possible mechanism of the nucleus accumbens and ventral pallidum 5-HT1B receptors underlying the antidepressant action of ketamine: a PET study with macaques.
Topics: Animals; Antidepressive Agents; Basal Forebrain; Carbon Radioisotopes; Excitatory Amino Acid Antagonists; Fenfluramine; Ketamine; Macaca; Male; Nucleus Accumbens; Positron-Emission Tomography; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, AMPA; Serotonin Plasma Membrane Transport Proteins | 2014 |
Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)-3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the
Topics: Amino Acids; Animals; Antidepressive Agents; Dioxoles; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Feeding Behavior; Fenclonine; Ketamine; Male; Mice, Inbred C57BL; Neuropsychological Tests; Piperazines; Piperidines; Pyridines; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Tryptophan Hydroxylase; Xanthenes | 2014 |
Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice.
Topics: Aggression; Animals; Animals, Outbred Strains; Cognition Disorders; Depression; Dopamine; Excitatory Amino Acid Antagonists; Hippocampus; Hyperkinesis; Male; Mice; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Serotonin; Social Behavior; Social Isolation | 2014 |
Differential regulation of peripheral IL-1β-induced mechanical allodynia and thermal hyperalgesia in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Male; Nerve Tissue Proteins; Pain Threshold; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion | 2014 |
A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia.
Topics: Adenosine Deaminase; Animals; Behavior, Animal; Brain; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mood Disorders; Motor Activity; Postmortem Changes; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; RNA Editing; RNA-Binding Proteins; Schizophrenia | 2014 |
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat.
Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus | 2014 |
Glutamate and dopamine transmission from midbrain dopamine neurons share similar release properties but are differentially affected by cocaine.
Topics: Animals; Channelrhodopsins; Dependovirus; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Quinoxalines; Receptors, Dopamine D2; Synaptic Transmission | 2014 |
Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats.
Topics: Animals; Antidepressive Agents; Benzhydryl Compounds; Depression; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Neuropsychological Tests; Prefrontal Cortex; Pyridines; Quinoxalines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Sirolimus; Swimming; Synapsins; Thiazoles; TOR Serine-Threonine Kinases | 2014 |
Roles of the spinal glutamatergic pathway activated through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, AMPA; Reflex; Serotonin Receptor Agonists; Sneezing; Urethra; Urinary Incontinence, Stress | 2015 |
Differential conduction velocity regulation in ipsilateral and contralateral collaterals innervating brainstem coincidence detector neurons.
Topics: Animals; Axons; Brain Stem; Chick Embryo; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Functional Laterality; GABA Antagonists; Imaging, Three-Dimensional; In Vitro Techniques; Male; Models, Neurological; Neural Conduction; Neural Pathways; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Valine | 2014 |
Optogenetic assessment of horizontal interactions in primary visual cortex.
Topics: Action Potentials; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Female; Luminescent Proteins; Male; Microscopy, Confocal; Neurons; Optogenetics; Orientation; Photic Stimulation; Quinoxalines; Rhodopsin; Synapsins; Tupaiidae; Valine; Visual Cortex; Visual Pathways | 2014 |
Down-regulation of endogenous KLHL1 decreases voltage-gated calcium current density.
Topics: Animals; Bicuculline; Calcium; Calcium Channels, N-Type; Calcium Channels, T-Type; Cells, Cultured; Down-Regulation; Electrophysiological Phenomena; Hippocampus; Humans; Microfilament Proteins; Quinoxalines; Rats; RNA Interference; RNA, Small Interfering; Synaptic Potentials | 2014 |
Insulin can induce the expression of a memory-related synaptic protein through facilitating AMPA receptor endocytosis in rat cortical neurons.
Topics: Animals; Cells, Cultured; Clathrin; Cytoskeletal Proteins; Endocytosis; Gene Expression Regulation; Insulin; Long-Term Potentiation; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Oligodeoxyribonucleotides, Antisense; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; src-Family Kinases | 2014 |
The synaptic and circuit mechanisms underlying a change in spatial encoding in the retina.
Topics: Action Potentials; Anesthetics, Local; Animals; Connexins; Electric Stimulation; Excitatory Amino Acid Antagonists; Gap Junction delta-2 Protein; In Vitro Techniques; Mice; Mice, Inbred C57BL; Models, Neurological; Nerve Net; Neurons; Patch-Clamp Techniques; Photic Stimulation; Quinoxalines; Retina; Stochastic Processes; Synapses; Tetrodotoxin; Visual Pathways | 2014 |
Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.
Topics: Action Potentials; Animals; Brain; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Glucuronosyltransferase; Hyaluronan Synthases; Hyaluronic Acid; In Vitro Techniques; Mice; Mice, Knockout; Models, Neurological; Mutation; Nerve Net; Neurons; Phosphopyruvate Hydratase; Quinoxalines | 2014 |
Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex.
Topics: Animals; Antidepressive Agents; Benzothiadiazines; Dihydro-beta-Erythroidine; Dorsal Raphe Nucleus; Dose-Response Relationship, Drug; Injections, Subcutaneous; Ketamine; Male; Microdialysis; Microinjections; Nicotinic Antagonists; Prefrontal Cortex; Quinoxalines; Rats; Receptors, AMPA; Receptors, Nicotinic; Serotonin; Spermine | 2014 |
Combined blockade of NMDA and AMPA receptors prevents acute kainate seizures and chronic kainate lethality in rats.
Topics: Adamantane; Amines; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intramuscular; Kainic Acid; Male; Memantine; N-Methylaspartate; Neuroprotective Agents; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Analysis | 2014 |
Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats.
Topics: Adaptation, Psychological; Amino Acids; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ketamine; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Swimming; Time Factors; Xanthenes | 2014 |
AMPA receptor inhibitors for the treatment of neurological disorders.
Topics: Aptamers, Nucleotide; Excitatory Amino Acid Antagonists; Humans; Nervous System Diseases; Quinoxalines; Receptors, AMPA | 2014 |
Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Differentiation; Cell Line; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophysiology; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Quinoxalines; Receptors, Ionotropic Glutamate | 2014 |
Developmental profiles of the intrinsic properties and synaptic function of auditory neurons in preterm and term baboon neonates.
Topics: Animals; Auditory Pathways; Bicuculline; Brain Stem; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Gene Expression Regulation, Developmental; Glycine Agents; Male; Microtubule-Associated Proteins; Neurons; Papio; Premature Birth; Quinoxalines; Strychnine; Synapses; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2014 |
Efficient, complete deletion of synaptic proteins using CRISPR.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Humans; In Vitro Techniques; Luminescent Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Red Fluorescent Protein; RNA; Synapses; Synaptophysin | 2014 |
Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats.
Topics: Analysis of Variance; Animals; Benzylamines; Bicuculline; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Estrous Cycle; Excitatory Amino Acid Agents; Extracellular Fluid; Female; GABA Agents; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Phosphinic Acids; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sex Differentiation; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2016 |
Distinct representation and distribution of visual information by specific cell types in mouse superficial superior colliculus.
Topics: Action Potentials; Animals; Channelrhodopsins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neurons; Pyridazines; Quinoxalines; Receptors, Neurotensin; Superior Colliculi; Valine; Vesicular Inhibitory Amino Acid Transport Proteins; Visual Fields; Visual Pathways | 2014 |
Pro-brain-derived neurotrophic factor inhibits GABAergic neurotransmission by activating endocytosis and repression of GABAA receptors.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Inhibitory Postsynaptic Potentials; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2014 |
Glutamatergic signaling at the vestibular hair cell calyx synapse.
Topics: Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hair Cells, Vestibular; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses; Synaptic Transmission | 2014 |
Comparison of the effects on brain stimulation reward of D1 blockade or D2 stimulation combined with AMPA blockade in the extended amygdala and nucleus accumbens.
Topics: Amygdala; Animals; Benzazepines; Choice Behavior; Conditioning, Operant; Drug Therapy, Combination; Glutamic Acid; Male; Medial Forebrain Bundle; Nucleus Accumbens; Quinoxalines; Quinpirole; Rats; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Stimulation | 2015 |
Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test.
Topics: Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Isoquinolines; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Swimming | 2015 |
Involvement of non-NMDA glutamate receptors of the hypothalamic paraventricular nucleus in the cardiovascular response to the microinjection of noradrenaline into the dorsal periaqueductal gray area of rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Bradycardia; Catheters, Indwelling; Excitatory Amino Acid Antagonists; Heart Rate; Isoquinolines; Male; Microinjections; Norepinephrine; Paraventricular Hypothalamic Nucleus; Periaqueductal Gray; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2015 |
In vivo coincidence detection in mammalian sound localization generates phase delays.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Brain; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gerbillinae; Glycine Agents; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Psychoacoustics; Quinoxalines; Reaction Time; Signal Detection, Psychological; Sound Localization; Strychnine | 2015 |
Differential frequency-dependent antidromic resonance of the Schaffer collaterals and mossy fibers.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Mossy Fibers, Hippocampal; Picrotoxin; Quinoxalines; Rats; Rats, Wistar | 2016 |
Involvement of serotonergic system in the effect of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test.
Topics: Animals; Excitatory Amino Acid Antagonists; Feeding Behavior; Fenclonine; Male; Mice; Piperazines; Pyridines; Quinoxalines; Receptor, Metabotropic Glutamate 5; Ritanserin; Serotonin; Serotonin Antagonists | 2015 |
Neuroprotective effect of noscapine on cerebral oxygen-glucose deprivation injury.
Topics: Animals; Brain Ischemia; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glucose; Hypoxia; Mice; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide; Noscapine; Primary Cell Culture; Quinoxalines; Thapsigargin | 2015 |
Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.
Topics: Animals; Antidepressive Agents; Brain; Dopaminergic Neurons; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2015 |
Dual-channel circuit mapping reveals sensorimotor convergence in the primary motor cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Channelrhodopsins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Light; Luminescent Proteins; Male; Mice; Motor Cortex; Nerve Net; Neurons; Piperazines; Quinoxalines; Sodium Channel Blockers; Somatosensory Cortex; Tetrodotoxin; Transduction, Genetic | 2015 |
Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Kynurenic Acid; Macaca; Male; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Temporal Lobe; Time Factors; Visual Perception | 2015 |
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Mice; Nitriles; Phenytoin; Pyridones; Quinoxalines; Receptors, AMPA; Seizures; Status Epilepticus | 2015 |
Selecting danger signals: dissociable roles of nucleus accumbens shell and core glutamate in predictive fear learning.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Excitatory Amino Acid Antagonists; Fear; Glutamic Acid; Male; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley | 2015 |
Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala.
Topics: Alcohol Drinking; Amygdala; Analysis of Variance; Animals; Central Nervous System Depressants; Conditioning, Classical; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Male; Quinoxalines; Rats; Rats, Long-Evans; Signal Transduction | 2015 |
Transient mitochondrial permeability transition mediates excitotoxicity in glutamate-sensitive NSC34D motor neuron-like cells.
Topics: Animals; Calcium Signaling; Cell Line, Transformed; Cyclosporine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hybrid Cells; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Motor Neurons; Oxidative Stress; Quinoxalines; Receptors, AMPA; Ruthenium Compounds; Time Factors; Transfection | 2015 |
Optogenetic stimulation of GABA neurons can decrease local neuronal activity while increasing cortical blood flow.
Topics: Animals; Cerebrovascular Circulation; Channelrhodopsins; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Interneurons; Lasers; Male; Mice; Optogenetics; Photic Stimulation; Quinoxalines | 2015 |
Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus.
Topics: Adenosine; Animals; CA1 Region, Hippocampal; Cadmium Chloride; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Morpholines; Neurons; Oxadiazoles; Presynaptic Terminals; Pyrimidines; Quinoxalines; Rats; Rats, Wistar | 2015 |
Spontaneous Activity Drives Local Synaptic Plasticity In Vivo.
Topics: Action Potentials; Animals; Animals, Newborn; Calcium; Computer Simulation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Nerve Net; Neuronal Plasticity; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Signal Transduction; Visual Cortex | 2015 |
The Antidepressant Effects of an mGlu2/3 Receptor Antagonist and Ketamine Require AMPA Receptor Stimulation in the mPFC and Subsequent Activation of the 5-HT Neurons in the DRN.
Topics: Amino Acids; Animals; Antidepressive Agents; Depression; Dorsal Raphe Nucleus; Fenclonine; Ketamine; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Serotonergic Neurons; Xanthenes | 2016 |
Glutamatergic Receptor Activation in the Commisural Nucleus Tractus Solitarii (cNTS) Mediates Brain Glucose Retention (BGR) Response to Anoxic Carotid Chemoreceptor (CChr) Stimulation in Rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Carotid Body; Glucose; Hypoxia; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Solitary Nucleus | 2015 |
Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice.
Topics: Adrenergic Agents; Animals; Bacterial Proteins; Channelrhodopsins; Corpus Striatum; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Oxidopamine; Parkinsonian Disorders; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Substantia Nigra | 2015 |
Non-Ionotropic NMDA Receptor Signaling Drives Activity-Induced Dendritic Spine Shrinkage.
Topics: Animals; Animals, Newborn; Calcium; Calmodulin; Cell Size; Dendritic Spines; Excitatory Amino Acid Antagonists; Female; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Magnesium; Male; Myosin-Light-Chain Kinase; Neuronal Plasticity; Neurons; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time-Lapse Imaging | 2015 |
Dendritic Organization of Olfactory Inputs to Medial Amygdala Neurons.
Topics: Action Potentials; Afferent Pathways; Animals; Calcium; Central Nervous System Stimulants; Corticomedial Nuclear Complex; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Sodium Channel Blockers; Tetrodotoxin; Valine | 2015 |
The role of the AMPA receptor and 5-HT(3) receptor on aggressive behavior and depressive-like symptoms in chronic social isolation-reared mice.
Topics: Aggression; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Depression; Food Preferences; Glutamate Decarboxylase; Hypothalamus; Injections, Intraperitoneal; Male; Mice; Microinjections; Motor Activity; Neurons; Ondansetron; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Serotonin, 5-HT3; Social Isolation | 2016 |
Concurrent antagonism of NMDA and AMPA receptors in the ventral tegmental area reduces the expression of conditioned approach learning in rats.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Quinoxalines; Rats, Long-Evans; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Ventral Tegmental Area | 2016 |
Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor.
Topics: Amino Acids; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Ferrets; gamma-Aminobutyric Acid; Glutamic Acid; Male; Patch-Clamp Techniques; Purkinje Cells; Pyridones; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Xanthenes | 2015 |
Interneurons spark seizure-like activity in the entorhinal cortex.
Topics: 4-Aminopyridine; Action Potentials; Animals; Disease Models, Animal; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Interneurons; Male; Piperazines; Quinoxalines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques | 2016 |
Peripheral NMDA Receptors Mediate Antidromic Nerve Stimulation-Induced Tactile Hypersensitivity in the Rat.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Electric Stimulation; Glutamic Acid; Hyperalgesia; Isoquinolines; Male; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Tibial Nerve | 2015 |
Correlated Synaptic Inputs Drive Dendritic Calcium Amplification and Cooperative Plasticity during Clustered Synapse Development.
Topics: Age Factors; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indoles; Membrane Potentials; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2016 |
A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing.
Topics: Action Potentials; Animals; Cholecystokinin; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Inflammation; Neural Pathways; Neuralgia; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Receptors, Oxytocin; Spinal Cord; Supraoptic Nucleus; Transduction, Genetic; Vasopressins; Vesicular Glutamate Transport Protein 2 | 2016 |
AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Calcium Signaling; Cerebral Ventricles; Cytokines; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Glycerol; Hemorrhage; Humans; Leukoencephalopathies; Male; Nervous System Diseases; Nitriles; Pregnancy; Pyridones; Quinoxalines; Rabbits; Receptors, AMPA; Recovery of Function | 2016 |
Insulin-Independent GABAA Receptor-Mediated Response in the Barrel Cortex of Mice with Impaired Met Activity.
Topics: Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABAergic Neurons; Homeodomain Proteins; Humans; Hypoglycemic Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Insulin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Picrotoxin; Proto-Oncogene Proteins c-met; Quinoxalines; Receptors, GABA-A; Transcription Factors | 2016 |
Involvement of hippocampal NMDA receptors in retrieval of spontaneous object recognition memory in rats.
Topics: Analysis of Variance; Animals; Discrimination Learning; Excitatory Amino Acid Agents; Hippocampus; Male; Mental Recall; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Time Factors; Valine | 2016 |
NBQX, a highly selective competitive antagonist of AMPA and KA ionotropic glutamate receptors, increases seizures and mortality following picornavirus infection.
Topics: Analysis of Variance; Animals; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mice; Mice, Inbred C57BL; Picornaviridae Infections; Plant Lectins; Quinoxalines; Seizures | 2016 |
The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits.
Topics: Action Potentials; Amino Acids; Animals; Antidepressive Agents; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice, Inbred BALB C; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Ventral Tegmental Area; Xanthenes | 2016 |
The effect of AMPA receptor blockade on spatial information acquisition, consolidation and expression in juvenile rats.
Topics: Age Factors; Animals; Behavior, Animal; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Male; Memory Consolidation; Quinoxalines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory | 2016 |
Effects of norepinephrine on spontaneous firing activity of cerebellar Purkinje cells in vivo in mice.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Mice; Mice, Inbred ICR; Norepinephrine; Purkinje Cells; Pyridazines; Quinoxalines; Receptors, AMPA; Receptors, GABA-A | 2016 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |
GABAB Receptors Tune Cortical Feedback to the Olfactory Bulb.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Channelrhodopsins; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Feedback; In Vitro Techniques; Lidocaine; Light; Mice; Mice, Inbred C57BL; Mice, Transgenic; Odorants; Olfactory Bulb; Olfactory Cortex; Olfactory Pathways; Quinoxalines; Receptors, GABA-B; Smell | 2016 |
Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495.
Topics: Amino Acids; Animals; Antidepressive Agents; Depressive Disorder; Excitatory Amino Acid Antagonists; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Scopolamine; Serotonin; Xanthenes | 2016 |
Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Dextromethorphan; Dose-Response Relationship, Drug; Exploratory Behavior; Ketamine; Male; Mice; Protein Precursors; Quinoxalines; Receptors, AMPA; Statistics, Nonparametric; Swimming | 2016 |
L-type calcium channels refine the neural population code of sound level.
Topics: 4-Aminopyridine; Acoustic Stimulation; Action Potentials; Amifampridine; Animals; Biophysical Phenomena; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inferior Colliculi; Mice; Mice, Inbred CBA; Neurons; Nimodipine; omega-Conotoxin GVIA; Potassium Channel Blockers; Quinoxalines; Sound; Wakefulness | 2016 |
Endogenous GABA controls oligodendrocyte lineage cell number, myelination, and CNS internode length.
Topics: Animals; Axons; Cell Differentiation; Cell Proliferation; Cerebral Cortex; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Mice; Mice, Transgenic; Myelin Sheath; Neurons; Oligodendroglia; Organ Culture Techniques; Organogenesis; Quinoxalines; Receptors, GABA; SOXE Transcription Factors; Synaptic Transmission; Tetrodotoxin | 2017 |
AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets.
Topics: Aggrecans; Animals; Anticonvulsants; Behavior, Animal; Chondroitin ABC Lyase; Disease Models, Animal; Down-Regulation; Epilepsy; Immunohistochemistry; Male; Neurocan; Pentylenetetrazole; Peripheral Nerves; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tenascin | 2016 |
[Analgesic effects of ionotropic glutamate receptor antagonists MK-801 and NBQX on collagen-induced arthritis rats].
Topics: Analgesics; Animals; Arthritis, Experimental; Cyclooxygenase 2; Dizocilpine Maleate; Edema; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Janus Kinase 3; Male; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.
Topics: 14-3-3 Proteins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Endosomal Sorting Complexes Required for Transport; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; HEK293 Cells; Humans; Lysine; Male; Mice, Knockout; Microscopy, Confocal; Mutation, Missense; Nedd4 Ubiquitin Protein Ligases; Neurons; Quinoxalines; Receptors, AMPA; Seizures; Ubiquitin-Protein Ligases | 2017 |
Blockade of glutamatergic transmission in the primate basolateral amygdala suppresses active behavior without altering social interaction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basolateral Nuclear Complex; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Interpersonal Relations; Macaca nemestrina; Male; Motor Activity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Social Behavior; Synaptic Transmission | 2017 |
Glial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats.
Topics: Affect; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Citalopram; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Limbic Lobe; Male; Neuroglia; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Quinoxalines; Raphe Nuclei; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Veratridine | 2017 |
Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice.
Topics: Animals; Antidepressive Agents; Citalopram; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Frontal Lobe; Ketamine; Male; Metabolome; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Quinoxalines; Receptor, Muscarinic M1; Receptors, AMPA; Scopolamine; Selective Serotonin Reuptake Inhibitors; TOR Serine-Threonine Kinases | 2017 |
AMPA receptor-mediated rapid EPSCs in vestibular calyx afferents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiadiazines; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dipeptides; Excitatory Postsynaptic Potentials; Female; Gerbillinae; Hair Cells, Vestibular; Male; Nifedipine; Quinoxalines; Receptors, AMPA; Strontium; Synapses | 2017 |
POm Thalamocortical Input Drives Layer-Specific Microcircuits in Somatosensory Cortex.
Topics: Animals; Channelrhodopsins; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Nerve Net; Neural Pathways; Parvalbumins; Piperidines; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Receptors, Serotonin, 5-HT3; Sodium Channel Blockers; Somatosensory Cortex; Somatostatin; Tetrodotoxin; Thalamic Nuclei; Vasoactive Intestinal Peptide | 2018 |
Orexin Directly Enhances the Excitability of Globus Pallidus Internus Neurons in Rat by Co-activating OX1 and OX2 Receptors.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; In Vitro Techniques; Interneurons; Isoquinolines; Male; Orexin Receptors; Orexins; Patch-Clamp Techniques; Pyridazines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2017 |
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Conditioning, Classical; Cues; Discrimination, Psychological; Electric Stimulation; Immobility Response, Tonic; Male; Microinjections; Neural Inhibition; Neural Pathways; Prefrontal Cortex; Punishment; Quinoxalines; Rats; Rats, Transgenic; Reward; Sucrose | 2017 |
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain.
Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine | 2018 |
Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanisms.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanones; Cyclohexylamines; Depression; Ketanserin; Male; Mice, Inbred ICR; Quinoxalines; Receptors, AMPA; Receptors, Serotonin; Serotonin Antagonists | 2017 |
A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Kainic Acid; Male; Mice; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors; Treatment Outcome | 2017 |
Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; DNA Methylation; Epigenesis, Genetic; Epilepsy; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Models, Biological; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Valine | 2017 |
Prefrontal Cortex Drives Distinct Projection Neurons in the Basolateral Amygdala.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Basolateral Nuclear Complex; Channelrhodopsins; Cholera Toxin; Dependovirus; Excitatory Postsynaptic Potentials; Genetic Vectors; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2017 |
Syringaresinol suppresses excitatory synaptic transmission and picrotoxin-induced epileptic activity in the hippocampus through presynaptic mechanisms.
Topics: Animals; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Furans; Glutamic Acid; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Lignans; Male; Mice; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Receptors, AMPA; Signal Transduction; Synaptic Transmission | 2018 |
The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Peptide Fragments; Protein Domains; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2018 |
Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats.
Topics: Alcohol Drinking; Animals; Depression; Kainic Acid; Ketamine; Male; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2018 |
Analysis of Feedback Signaling from Horizontal Cells to Photoreceptors in Mice.
Topics: Animals; Calcium; Calcium Channels; Connexins; Feedback, Physiological; Immunohistochemistry; Kainic Acid; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Confocal; Molecular Imaging; Optical Imaging; Photoreceptor Cells, Vertebrate; Quinoxalines; Retinal Horizontal Cells | 2018 |
Differential electrical responses in retinal ganglion cell subtypes: effects of synaptic blockade and stimulating electrode location.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Quinoxalines; Retinal Ganglion Cells; Synapses | 2018 |
Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.
Topics: Animals; Auditory Perception; Cerebral Cortex; Female; Male; Mice, Inbred C57BL; Neuronal Plasticity; Quinoxalines; Receptors, AMPA; Seizures; Synapses; Thalamus | 2018 |
Kcnj6(GIRK2) trisomy is not sufficient for conferring the susceptibility to infantile spasms seen in the Ts65Dn mouse model of down syndrome.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Electroencephalography; Embryo, Mammalian; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Hippocampus; Humans; In Vitro Techniques; Infant; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Peptide Hydrolases; Quinoxalines; Sodium Oxybate; Spasms, Infantile; Trisomy | 2018 |
Origin and classification of spontaneous discharges in mouse superficial dorsal horn neurons.
Topics: Action Potentials; Animals; Chromosome Pairing; Membrane Potentials; Mice; Neurons; Picrotoxin; Posterior Horn Cells; Quinoxalines; Riluzole; Sodium; Strychnine; Tetrodotoxin | 2018 |
Long-term neurotoxic effects of domoic acid on primary dopaminergic neurons.
Topics: Animals; Apoptosis; Cells, Cultured; Dizocilpine Maleate; Dopaminergic Neurons; Kainic Acid; Membrane Potential, Mitochondrial; Mesencephalon; Mice; Neuromuscular Depolarizing Agents; Neurotoxins; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2018 |
Spontaneous activities in baroreflex afferent pathway contribute dominant role in parasympathetic neurocontrol of blood pressure regulation.
Topics: Action Potentials; Afferent Pathways; Analysis of Variance; Animals; Baroreflex; Blood Pressure; Brain Stem; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Ovariectomy; Peptides; Potassium Channel Blockers; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Vagus Nerve | 2018 |
AMPA receptors and seizures mediate hippocampal radial glia-like stem cell proliferation.
Topics: Animals; Animals, Newborn; Benzodiazepines; Cell Death; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Ki-67 Antigen; Male; Membrane Potentials; Nerve Tissue Proteins; Neuroglia; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Stem Cells | 2018 |
Dynamics of synaptic extracellular field potentials in the nucleus laminaris of the barn owl.
Topics: Animals; Basolateral Nuclear Complex; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Quinoxalines; Strigiformes; Synaptic Potentials | 2019 |
Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Topics: Age Factors; Animals; Hippocampus; Ketamine; Male; Mice; Piperidines; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Social Behavior; Stress, Psychological | 2019 |
Role of AMPA receptor stimulation and TrkB signaling in the antidepressant-like effect of ketamine co-administered with a group II mGlu receptor antagonist, LY341495, in the forced swim test in rats.
Topics: Amino Acids; Animals; Antidepressive Agents; Azepines; Benzamides; Depression; Depressive Disorder; Excitatory Amino Acid Antagonists; Ketamine; Male; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Xanthenes | 2019 |
Temporal-spacial relationships between facial stimulation-evoked filed potential responses in mouse cerebellar granular layer and molecular layer.
Topics: Animals; Cerebellar Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; Face; Female; GABA Antagonists; Male; Mice; Physical Stimulation; Pyridazines; Quinoxalines; Touch; Vibrissae | 2019 |
AMPA Receptor in Ventromedial Prefrontal Cortex Plays Different Roles in the Recent and Remote Retrieval of Morphine-Associated Memory.
Topics: Animals; Cell Membrane; Male; Memory; Morphine; Prefrontal Cortex; Quinoxalines; Rats, Sprague-Dawley; Receptors, AMPA | 2019 |
(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism.
Topics: Animals; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Ketamine; Lipopolysaccharides; Male; Mice; Microdialysis; Microinjections; Norepinephrine; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Serotonin; Stereoisomerism | 2019 |
Do stereoisomers of homocysteic acid exhibit different convulsant action in immature rats?
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Dizocilpine Maleate; Homocysteine; Male; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Stereoisomerism | 2019 |
Endogenous glutamatergic inputs to the Parabrachial Nucleus/Kölliker-Fuse Complex determine respiratory rate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kolliker-Fuse Nucleus; Male; Microinjections; Parabrachial Nucleus; Quinoxalines; Rabbits; Respiratory Center; Respiratory Rate | 2020 |
Involvement of Hippocampal AMPA Receptors in Electroacupuncture Attenuating Depressive-Like Behaviors and Regulating Synaptic Proteins in Rats Subjected to Chronic Unpredictable Mild Stress.
Topics: Animals; Behavior, Animal; Chronic Disease; Depression; Electroacupuncture; Excitatory Amino Acid Antagonists; Hippocampus; Male; Neuronal Plasticity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Synapses | 2020 |
Allopregnanolone induces antidepressant-like effects through BDNF-TrkB signaling independent from AMPA receptor activation in a rat learned helplessness model of depression.
Topics: Animals; Antidepressive Agents; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Helplessness, Learned; Male; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Signal Transduction | 2020 |
Systemic Administration of the AMPA Receptor Antagonist, NBQX, Reduces Alcohol Drinking in Male C57BL/6J, But Not Female C57BL/6J or High-Alcohol-Preferring, Mice.
Topics: Alcohol Drinking; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Quinoxalines; Receptors, AMPA; Sex Factors | 2020 |
Quantifying Spontaneous Ca2+ Fluxes and their Downstream Effects in Primary Mouse Midbrain Neurons.
Topics: Animals; Calcium; Calcium Signaling; Caspase 3; Cells, Cultured; Dependovirus; Dopaminergic Neurons; Embryo, Mammalian; Genetic Vectors; Glutamates; Image Processing, Computer-Assisted; Mesencephalon; Mice; Quinoxalines; Receptors, AMPA; Tyrosine 3-Monooxygenase | 2020 |
Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice.
Topics: Animals; Behavior, Animal; Chloroquine; Cyclopropanes; Disease Models, Animal; Histamine; Hypodermoclysis; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Nitriles; Pruritus; Pyridones; Quinoxalines; Receptors, AMPA | 2020 |
Factors regulating serine racemase and d-amino acid oxidase expression in the mouse striatum.
Topics: Animals; Brain; Cocaine; Corpus Striatum; D-Amino-Acid Oxidase; Dizocilpine Maleate; Female; Gene Expression; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinoxalines; Racemases and Epimerases; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine | 2021 |
Ligand-directed two-step labeling to quantify neuronal glutamate receptor trafficking.
Topics: Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fluorescein; Fluorescent Dyes; Gene Expression; Half-Life; HEK293 Cells; Hippocampus; Humans; Ligands; Mice; Mice, Inbred ICR; Neurons; Primary Cell Culture; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staining and Labeling | 2021 |
NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats.
Topics: Animals; Dose-Response Relationship, Drug; Male; Methamphetamine; Nicotine; Quinoxalines; Rats; Rats, Wistar; Recurrence; Self Administration | 2021 |
The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain.
Topics: Animals; Brain; CA3 Region, Hippocampal; Eukaryotic Initiation Factor-2; Genes, Reporter; Mice; Muscimol; Nerve Tissue Proteins; Phosphorylation; Picrotoxin; Prosencephalon; Protein Processing, Post-Translational; Pyramidal Cells; Quinoxalines; Restraint, Physical; Stress, Physiological; Strychnine | 2021 |
Intra-dorsolateral striatal AMPA receptor antagonism reduces binge-like alcohol drinking in male and female C57BL/6J mice.
Topics: Animals; Binge Drinking; Blood Alcohol Content; Excitatory Amino Acid Antagonists; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Quinoxalines; Receptors, AMPA; Saccharin | 2022 |
The role of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type receptor modulators in object recognition memory reconsolidation.
Topics: Animals; Dioxoles; Learning; Memory Consolidation; Memory, Long-Term; Mice; Piperidines; Quinoxalines; Receptors, AMPA; Recognition, Psychology | 2022 |