Compounds > quinone methide
Page last updated: 2024-09-02

quinone methide and toremifene

quinone methide has been researched along with toremifene in 3 studies

Compound Research Comparison

Studies
(quinone methide)		Trials
(quinone methide)		Recent Studies (post-2010)
(quinone methide)		Studies
(toremifene)		Trials
(toremifene)		Recent Studies (post-2010) (toremifene)
3740232602109133

Protein Interaction Comparison

ProteinTaxonomyquinone methide (IC50)toremifene (IC50)
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.58

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bolton, JL; Fan, PW; Zhang, F1
Bolton, JL; van Breemen, RB; Yang, Y; Yao, D; Yu, L; Zhang, F1
Bolton, JL; Burdette, JE; Li, Y; Liu, X; Pisha, E; Tonetti, DA; Yao, D; Yao, J1

Other Studies

3 other study(ies) available for quinone methide and toremifene

ArticleYear
4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
    Chemical research in toxicology, 2000, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cytochrome P-450 Enzyme System; Estrogen Receptor Modulators; Female; Glutathione; Humans; Hydroxylation; Indolequinones; Indoles; Mass Spectrometry; Oxidation-Reduction; Quinones; Rats; Rats, Sprague-Dawley; Tamoxifen; Toremifene; Tumor Cells, Cultured

2000
Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones.
    Chemical research in toxicology, 2001, Volume: 14, Issue:12

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Survival; Deoxyribonucleosides; DNA Adducts; Female; Glutathione; Indolequinones; Indoles; Microsomes, Liver; Quinones; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Toremifene; Tumor Cells, Cultured

2001
Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
    Chemical research in toxicology, 2003, Volume: 16, Issue:7

    Topics: Binding, Competitive; Breast Neoplasms; Catechols; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Drug Screening Assays, Antitumor; Estradiol; Estrogen Receptor Modulators; Female; Humans; Indolequinones; Quinones; Receptors, Estrogen; Tamoxifen; Toremifene

2003