quinone methide has been researched along with tamoxifen in 8 studies
| Studies (quinone methide) | Trials (quinone methide) | Recent Studies (post-2010) (quinone methide) | Studies (tamoxifen) | Trials (tamoxifen) | Recent Studies (post-2010) (tamoxifen) |
|---|---|---|---|---|---|
| 374 | 0 | 232 | 20,630 | 2,227 | 6,256 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beland, FA; Marques, MM | 1 |
| Bolton, JL; Fan, PW; Zhang, F | 1 |
| Bolton, JL; Fan, PW | 1 |
| Bolton, JL; van Breemen, RB; Yang, Y; Yao, D; Yu, L; Zhang, F | 1 |
| Bolton, JL; Burdette, JE; Li, Y; Liu, X; Pisha, E; Tonetti, DA; Yao, D; Yao, J | 1 |
| Amatore, C; Buriez, O; Frapart, YM; Hamels, D; Hillard, EA; Jaouen, G; Labbé, E; Mansuy, D; Messina, P; Top, S; Vessières, A | 1 |
| D'Agostino, J; Hollenberg, PF; Sridar, C | 1 |
| Bindoli, A; Citta, A; Folda, A; Jaouen, G; Lee, HZ; Leong, WK; Rigobello, MP; Salmain, M; Scalcon, V; Top, S; Vessières, A | 1 |
8 other study(ies) available for quinone methide and tamoxifen
| Article | Year |
|---|---|
Identification of tamoxifen-DNA adducts formed by 4-hydroxytamoxifen quinone methide.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Adducts; Indolequinones; Indoles; Quinones; Salmon; Spectrometry, Mass, Fast Atom Bombardment; Tamoxifen | 1997 |
4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cytochrome P-450 Enzyme System; Estrogen Receptor Modulators; Female; Glutathione; Humans; Hydroxylation; Indolequinones; Indoles; Mass Spectrometry; Oxidation-Reduction; Quinones; Rats; Rats, Sprague-Dawley; Tamoxifen; Toremifene; Tumor Cells, Cultured | 2000 |
Bioactivation of tamoxifen to metabolite E quinone methide: reaction with glutathione and DNA.
Topics: Antineoplastic Agents, Phytogenic; Biotransformation; DNA; DNA Adducts; Glutathione; Indolequinones; Indoles; Microsomes, Liver; Quinones; Spectrum Analysis; Tamoxifen | 2001 |
Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Survival; Deoxyribonucleosides; DNA Adducts; Female; Glutathione; Indolequinones; Indoles; Microsomes, Liver; Quinones; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Toremifene; Tumor Cells, Cultured | 2001 |
Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
Topics: Binding, Competitive; Breast Neoplasms; Catechols; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Drug Screening Assays, Antitumor; Estradiol; Estrogen Receptor Modulators; Female; Humans; Indolequinones; Quinones; Receptors, Estrogen; Tamoxifen; Toremifene | 2003 |
Deciphering the activation sequence of ferrociphenol anticancer drug candidates.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Female; Ferrous Compounds; Humans; Indolequinones; Models, Molecular; Molecular Structure; Oxidation-Reduction; Tamoxifen | 2012 |
Bioactivation of the cancer chemopreventive agent tamoxifen to quinone methides by cytochrome P4502B6 and identification of the modified residue on the apoprotein.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Apoproteins; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2B6; Glutathione; Humans; Hydroxylation; Indolequinones; Microsomes, Liver; Oxidoreductases, N-Demethylating; Tamoxifen | 2012 |
Osmocenyl-tamoxifen derivatives target the thioredoxin system leading to a redox imbalance in Jurkat cells.
Topics: Antineoplastic Agents; Cell Death; Coordination Complexes; Ferrous Compounds; Gene Expression; Glutathione; Humans; Indolequinones; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Organometallic Compounds; Osmium; Oxidation-Reduction; Oxidative Stress; Peroxiredoxin III; Reactive Oxygen Species; Tamoxifen; Thioredoxin Reductase 1; Thioredoxins | 2016 |