quinone methide has been researched along with raloxifene hydrochloride in 2 studies
| Studies (quinone methide) | Trials (quinone methide) | Recent Studies (post-2010) (quinone methide) | Studies (raloxifene hydrochloride) | Trials (raloxifene hydrochloride) | Recent Studies (post-2010) (raloxifene hydrochloride) |
|---|---|---|---|---|---|
| 374 | 0 | 232 | 2,818 | 481 | 810 |
| Protein | Taxonomy | quinone methide (IC50) | raloxifene hydrochloride (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.0053 | |
| Gastric inhibitory polypeptide receptor | Homo sapiens (human) | 0.0004 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.1297 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolton, JL; Li, W; Liu, H; Luckie, C; Thatcher, GR; van Breemen, RB; Yu, L; Zhang, F | 1 |
| Bolton, JL; Liu, H; Qin, Z; Thatcher, GR | 1 |
2 other study(ies) available for quinone methide and raloxifene hydrochloride
| Article | Year |
|---|---|
Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones.
Topics: Animals; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Glutathione; Humans; Indolequinones; Microsomes, Liver; Oxidation-Reduction; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators | 2004 |
Uterine peroxidase-catalyzed formation of diquinone methides from the selective estrogen receptor modulators raloxifene and desmethylated arzoxifene.
Topics: Alkylation; Animals; Catalysis; Female; Glutathione; Horseradish Peroxidase; Indolequinones; Microsomes; Piperidines; Quinones; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators; Thiophenes; Uterus | 2007 |