quinone methide has been researched along with aspirin in 2 studies
| Studies (quinone methide) | Trials (quinone methide) | Recent Studies (post-2010) (quinone methide) | Studies (aspirin) | Trials (aspirin) | Recent Studies (post-2010) (aspirin) |
|---|---|---|---|---|---|
| 374 | 0 | 232 | 48,947 | 6,817 | 13,778 |
| Protein | Taxonomy | quinone methide (IC50) | aspirin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.35 | |
| Integrin beta-3 | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.8252 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 1.375 | |
| Integrin alpha-IIb | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.271 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 2.4 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 2.15 | |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | 0.3 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 2.4 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.35 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4081 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bos, C; de Esch, IJ; Hulsman, N; Jongejan, A; Leurs, R; Medema, JP; Richel, D; Smit, MJ; Wijtmans, M | 1 |
| Abdul-Hay, S; Dunlap, T; Litosh, V; Luo, J; Piyankarage, SC; Thatcher, GR; Vanni, M; Wijewickrama, GT | 1 |
2 other study(ies) available for quinone methide and aspirin
| Article | Year |
|---|---|
Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin.
Topics: Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indolequinones; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitric Oxide Donors; Structure-Activity Relationship | 2007 |
Quinone-induced activation of Keap1/Nrf2 signaling by aspirin prodrugs masquerading as nitric oxide.
Topics: Animals; Aspirin; Cell Line, Tumor; DNA Damage; Glutathione; Glutathione S-Transferase pi; Humans; Indolequinones; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Nitric Oxide; Prodrugs | 2012 |