quinolinic acid has been researched along with oxidopamine in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.00) | 18.7374 |
| 1990's | 20 (40.00) | 18.2507 |
| 2000's | 22 (44.00) | 29.6817 |
| 2010's | 6 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Churchill, L; Dilts, RP; Kalivas, PW | 1 |
| Dunbar, JS; Hitchcock, K; Latimer, M; Rugg, EL; Ward, N; Winn, P | 1 |
| Burton, S; Daya, S; Potgieter, B | 1 |
| Everitt, BJ; Jarrard, LE; Robbins, TW; Selden, NR | 1 |
| Martinez-Mir, MI; Palacios, JM; Probst, A | 1 |
| Boulu, RG; Buisson, A; Pateau, V; Plotkine, M | 1 |
| Palacios, JM; Waeber, C; Zhang, LA | 1 |
| Okuno, E; Schwarcz, R; White, RJ | 1 |
| Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
| Stoessl, AJ | 1 |
| Cano, J; Machado, A; Revuelta, M; Romero-Ramos, M; Venero, JL | 1 |
| Gramsbergen, JB; Sloot, WN | 1 |
| Brown, EE; Fibiger, HC | 1 |
| Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Henderson, G; Hicks, GA; Hudson, AL | 1 |
| Beninger, RJ; Boegman, RJ; Colton, AM; Ingles, JL; Jhamandas, K | 1 |
| Granata, R; Jenner, P; Laboyrie, PM; Marsden, CD; Quinn, NP; Wenning, GK | 1 |
| Furtado, JC; Garside, S; Mazurek, MF | 1 |
| Honey, CR; Shen, H | 1 |
| Collins, P; Dias, R; Everitt, BJ; Robbins, TW; Roberts, AC | 1 |
| Burke, RE; Jeon, BS; Kholodilov, NG; Kim, SY; Oo, TF; Srinivasan, A; Stefanis, L; Tomaselli, KJ | 1 |
| Cano, J; Echevarría, M; Ilundáin, AA; Machado, A; Vargas, C; Venero, JL; Vizuete, ML | 1 |
| Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK | 1 |
| Guzman, R; Lövblad, KO; Meyer, M; Schroth, G; Spenger, C; Widmer, HR | 1 |
| Donaldson, D; Levivier, M | 1 |
| Humpel, C; Levivier, M; Poewe, W; Puschban, Z; Scherfler, C; Seppi, K; Stefanova, N; Waldner, R; Wenning, GK | 1 |
| Ghorayeb, I; Goebel, GP; Jellinger, K; Poewe, W; Puschban, Z; Scherfler, C; Tison, F; Wenning, GK | 1 |
| Artymyshyn, RP; Kung, HF; Kung, MP; Lucki, I; McGonigle, P; Stanwood, GD | 1 |
| Fernagut, PO; Ghorayeb, I; Puschban, Z; Rouland, R; Scherfler, C; Tison, F; Wenning, GK | 1 |
| Burke, RE; El-Khodor, BF; Kholodilov, N; Neystat, M; Oo, TF; Rzhetskaya, M; Wilson, A; Yarygina, O | 1 |
| Baird, AL; Dunnett, SB; Jeyasingham, RA; Meldrum, A | 1 |
| Brundin, P; Castilho, RF; DiFiglia, M; Hansson, O; Petersén, A; Przedborski, S; Puschban, Z; Rice, M; Romero, N; Sapp, E; Sulzer, D | 1 |
| Rassoulpour, A; Schwarcz, R; Wu, HQ | 1 |
| Burke, RE; Oo, TF; Siman, R | 1 |
| Groenewegen, HJ; Jurzak, M; Langlois, X; Leysen, JE; Taymans, JM; Te Riele, P; Wintmolders, C | 1 |
| Bezard, E; Diguet, E; Gross, CE; Stefanova, N; Tison, F; Wenning, GK | 1 |
| Jacques, DB; Kopyov, O; Olds, ME | 1 |
| Egger, KE; Jellinger, KA; Mantoan, L; Poewe, W; Stefanova, N; Wenning, GK | 1 |
| Diguet, E; Poewe, W; Puschban, Z; Sather, T; Scherfler, C; Stefanova, N; Tison, F; Wenning, GK | 1 |
| Cortés, R; Mengod, G; Vilaró, MT | 1 |
| Alberch, J; Checa, N; Pezzi, S | 1 |
| Brachet, P; Jaafar, A; Peschanski, M; Robichon, R; Terqui, M | 1 |
| Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Tomás-Camardiel, M | 1 |
| Hida, H; Kim, TS; Masuda, T; Misumi, S; Nishino, H; Urakawa, S | 1 |
| Döbrössy, MD; García, J; Kaindlstorfer, C; Nikkhah, G; Wenning, GK; Winkler, C | 1 |
| Gago, B; Marin, C; Obeso, JA; Rodríguez-Oroz, MC | 1 |
| Boraud, T; Dejean, C; Fourneaux, B; Leinekugel, X; Retailleau, A | 1 |
| Bannerman, DM; Boorman, ED; Croxson, PL; Rushworth, MF; Walton, ME | 1 |
| Jeon, SR; Kim, YH; Shin, ES; Yoon, HH | 1 |
| Aschner, M; Colonnello, A; de Lima, ME; García-Contreras, R; Kotlar, I; Ortíz-Plata, A; Santamaría, A; Soares, FAA | 1 |
50 other study(ies) available for quinolinic acid and oxidopamine
| Article | Year |
|---|---|
Autoradiographic localization of gamma-aminobutyric acidA receptors within the ventral tegmental area.
Topics: Animals; Autoradiography; Male; Muscimol; Neurons; Nucleus Accumbens; Oxidopamine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tegmentum Mesencephali; Tissue Distribution | 1992 |
Excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. II. Examination of eating and drinking, rotation, and reaching and grasping following unilateral ibotenate or quinolinate lesions.
Topics: Animals; Behavior, Animal; Body Weight; Choline O-Acetyltransferase; Drinking Behavior; Feeding Behavior; Ibotenic Acid; Immunohistochemistry; Male; Mesencephalon; Neurons; Oxidopamine; Pons; Quinolinic Acid; Rats; Rotation; Sympathectomy, Chemical; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase | 1992 |
Melatonin modulates apomorphine-induced rotational behaviour.
Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Huntington Disease; Hydroxydopamines; Male; Melatonin; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues.
Topics: Amygdala; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Convulsants; Cues; Hippocampus; Hydroxydopamines; Ibotenic Acid; Male; Norepinephrine; Oxidopamine; Quinolinic Acid; Quinolinic Acids; Rats; Reinforcement, Psychology; Sympathectomy, Chemical | 1991 |
Adenosine A2 receptors: selective localization in the human basal ganglia and alterations with disease.
Topics: Adenosine; Aged; Aged, 80 and over; Animals; Basal Ganglia; Corpus Striatum; Female; Guinea Pigs; Humans; Huntington Disease; Male; Middle Aged; Nerve Degeneration; Organ Specificity; Oxidopamine; Parkinson Disease; Quinolinic Acid; Quinolinic Acids; Receptors, Purinergic | 1991 |
Nigrostriatal pathway modulates striatum vulnerability to quinolinic acid.
Topics: Animals; Corpus Striatum; Desipramine; Dopamine; Male; Nerve Degeneration; Neural Pathways; Oxidopamine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
5-HT1D receptors in the guinea pig brain: pre- and postsynaptic localizations in the striatonigral pathway.
Topics: Animals; Corpus Striatum; Guinea Pigs; Hydroxydopamines; Male; Neural Pathways; Oxidopamine; Quinolinic Acid; Quinolinic Acids; Receptors, Serotonin; Substantia Nigra; Synapses | 1990 |
Basal ganglia lesions in the rat: effects on quinolinic acid metabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Corpus Striatum; Hydroxydopamines; Ibotenic Acid; Male; Neuroglia; Neurotoxins; Oxidopamine; Pentosyltransferases; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Norepinephrine modulates seizures induced by quinolinic acid in rats: selective and distinct roles of alpha-adrenoceptor subtypes.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Hippocampus; Hydroxydopamines; Male; Methoxamine; Norepinephrine; Oxidopamine; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Seizures | 1987 |
Localization of striatal and nigral tachykinin receptors in the rat.
Topics: Animals; Autoradiography; Corpus Striatum; Male; Mazindol; Medial Forebrain Bundle; Oxidopamine; Peptide Fragments; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Substantia Nigra; Tissue Distribution | 1994 |
Intrastriatal quinolinic acid injections protect against 6-hydroxydopamine-induced lesions of the dopaminergic nigrostriatal system.
Topics: Animals; Corpus Striatum; Dopamine; Female; Injections; Neuroprotective Agents; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Substantia Nigra | 1995 |
Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia.
Topics: Animals; Axons; Basal Ganglia; Biological Transport; Colchicine; Corpus Striatum; Male; Manganese; Microinjections; Oxidopamine; Quinolinic Acid; Radioisotopes; Rats; Rats, Wistar; Substantia Nigra | 1994 |
Differential effects of excitotoxic lesions of the amygdala on cocaine-induced conditioned locomotion and conditioned place preference.
Topics: Amygdala; Animals; Cocaine; Conditioning, Operant; Gliosis; Male; Motor Activity; Oxidopamine; Quinolinic Acid; Rats; Reward | 1993 |
Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Antihypertensive Agents; Autoradiography; Basal Ganglia; Benserazide; Binding Sites; Dopamine Agents; Ergolines; Levodopa; Male; Neural Pathways; Neurons; Oxidopamine; Phenethylamines; Quinolinic Acid; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Stereotyped Behavior | 1994 |
Localization of high affinity [3H]glibenclamide binding sites within the substantia nigra zona reticulata of the rat brain.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Glyburide; Male; Oxidopamine; Potassium Channels; Protein Binding; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Drug; Substantia Nigra | 1994 |
Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry.
Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Neostriatum; Neurotoxins; Oxidopamine; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase | 1994 |
Reversal of behavioural abnormalities by fetal allografts in a novel rat model of striatonigral degeneration.
Topics: Amphetamines; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Fetal Tissue Transplantation; Graft Survival; Immunohistochemistry; Male; Mesencephalon; Nerve Degeneration; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Substantia Nigra; Transplantation, Homologous | 1996 |
Dopamine-glutamate interactions in the striatum: behaviourally relevant modification of excitotoxicity by dopamine receptor-mediated mechanisms.
Topics: Analysis of Variance; Animals; Corpus Striatum; Dopamine; Functional Laterality; Glutamic Acid; Haloperidol; Male; Maze Learning; Motor Activity; Neurotoxins; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Substantia Nigra | 1996 |
Circling behaviour in 6-hydroxydopamine-lesioned rats given pulsed levodopa is reduced more by lesions in the entopeduncular nucleus/substantia nigra pars reticulata than in the subthalamic nucleus.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Benserazide; Corpus Striatum; Dopamine Agents; Dopamine Agonists; Injections, Intraperitoneal; Levodopa; Male; Motor Activity; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Substantia Nigra; Thalamic Nuclei | 1998 |
Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: effects of excitotoxic lesions and dopamine depletions of the prefrontal cortex.
Topics: Animals; Callithrix; Dopamine; Memory; Oxidopamine; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Reproducibility of Results; Spatial Behavior | 1998 |
Activation of caspase-3 in developmental models of programmed cell death in neurons of the substantia nigra.
Topics: Animals; Apoptosis; Blotting, Northern; Caspase 3; Caspases; Corpus Striatum; Dopamine; Enzyme Activation; Gene Expression; Models, Biological; Neurons; Oxidopamine; Quinolinic Acid; Rats; RNA, Messenger; Substantia Nigra | 1999 |
Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema.
Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Axotomy; Blood-Brain Barrier; Brain Edema; Brain Injuries; Corpus Striatum; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Hybridization; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; RNA, Messenger; Substantia Nigra; Up-Regulation; Water-Electrolyte Balance | 1999 |
Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc
Topics: Amphetamine; Animals; Apomorphine; Atrophy; Autoradiography; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Fetal Tissue Transplantation; Male; Mazindol; Nerve Degeneration; Neurons; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Imaging the rat brain on a 1.5 T clinical MR-scanner.
Topics: Animals; Artifacts; Blood-Brain Barrier; Brain; Brain Tissue Transplantation; Female; Huntington Disease; Image Processing, Computer-Assisted; Immunohistochemistry; Magnetic Resonance Imaging; Movement; Oxidopamine; Parkinson Disease, Secondary; Perfusion; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympatholytics | 2000 |
Metabolic changes after injection of quinolinic acid or 6-hydroxydopamine in the rat striatum: a time-course study using cytochrome oxidase and glycogene phosphorylase a histochemistry.
Topics: Animals; Autoradiography; Benzazepines; Biomarkers; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electron Transport Complex IV; Glycogen; Huntington Disease; Male; Mazindol; Microinjections; Nerve Degeneration; Oxidopamine; Parkinson Disease; Phosphorylase a; Quinolinic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Sympatholytics; Tritium | 2000 |
Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Apomorphine; Autoradiography; Binding, Competitive; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Fetal Tissue Transplantation; Male; Membrane Proteins; Motor Activity; Multiple System Atrophy; Nerve Tissue Proteins; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Striatonigral Degeneration; Treatment Failure | 2000 |
Complex motor disturbances in a sequential double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glial Fibrillary Acidic Protein; Male; Motor Activity; Multiple System Atrophy; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Striatonigral Degeneration; Substantia Nigra; Tyrosine 3-Monooxygenase | 2000 |
Quantitative autoradiographic mapping of rat brain dopamine D3 binding with [(125)I]7-OH-PIPAT: evidence for the presence of D3 receptors on dopaminergic and nondopaminergic cell bodies and terminals.
Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Brain Chemistry; Iodine Radioisotopes; Male; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes | 2000 |
Simultaneous intrastriatal 6-hydroxydopamine and quinolinic acid injection: a model of early-stage striatonigral degeneration.
Topics: Animals; Behavior, Animal; Cell Count; Corpus Striatum; Disease Models, Animal; Forelimb; Male; Microinjections; Motor Activity; Motor Skills; Multiple System Atrophy; Neurodegenerative Diseases; Neurons; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Reaction Time; Substantia Nigra; Touch; Tyrosine 3-Monooxygenase | 2001 |
Expression of cyclin-dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo.
Topics: Animals; Antibodies; Apoptosis; Axotomy; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Epitopes; Gene Expression Regulation, Enzymologic; Medial Forebrain Bundle; Munc18 Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; Oxidopamine; Phosphorylation; Quinolinic Acid; Rats; RNA, Messenger; Substantia Nigra; Sympatholytics; tau Proteins; Vesicular Transport Proteins | 2001 |
Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat.
Topics: Amphetamine; Animals; Apomorphine; Central Nervous System Stimulants; Corpus Striatum; Denervation; Dopamine Agonists; Female; Functional Laterality; Hand Strength; Motor Activity; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics | 2001 |
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.
Topics: Aging; Animals; Ascorbic Acid; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Drug Resistance; Exons; Glutathione; Huntington Disease; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Electron; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidative Stress; Oxidopamine; Phosphoproteins; Quinolinic Acid; Retrograde Degeneration; Substantia Nigra; Superoxide Dismutase; Superoxide Dismutase-1; Uric Acid | 2001 |
Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Space; Kynurenic Acid; Levodopa; Male; Neostriatum; Neurons; Neurotoxins; Oxidopamine; Parkinson Disease; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Substantia Nigra | 2002 |
Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra.
Topics: Actins; Animals; Antibody Specificity; Apoptosis; Caspases; Cell Compartmentation; Cell Nucleus; Cytoplasm; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Humans; Immunohistochemistry; Neuroblastoma; Neurons; Oxidopamine; Parkinson Disease, Secondary; Peptide Fragments; Quinolinic Acid; Rats; Spectrin; Substantia Nigra; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2002 |
Detailed localization of regulator of G protein signaling 2 messenger ribonucleic acid and protein in the rat brain.
Topics: Animals; Brain; DNA, Complementary; Dopamine; GTP Phosphohydrolases; GTP-Binding Proteins; Male; Molecular Sequence Data; Neostriatum; Neural Pathways; Neurons; Neurotoxins; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; RGS Proteins; RNA, Messenger; Second Messenger Systems; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Substantia Nigra; Synaptic Transmission | 2002 |
Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Clinical Trials as Topic; Corpus Striatum; Disease Models, Animal; Microglia; Minocycline; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Primates; Quinolinic Acid; Rats; Rats, Wistar; Substantia Nigra; Treatment Failure | 2004 |
Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Huntington Disease; Locomotion; Male; Neurotoxins; Oxidopamine; Parkinson Disease; Quinolinic Acid; Rats; Rotation; Stereotyped Behavior; Substantia Nigra | 2005 |
Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Caspase Inhibitors; Cell Count; Cell Size; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Functional Laterality; Immunohistochemistry; Male; Motor Activity; Multiple System Atrophy; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oligopeptides; Oxidopamine; Phosphoproteins; Quinolinic Acid; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 2005 |
Riluzole improves motor deficits and attenuates loss of striatal neurons in a sequential double lesion rat model of striatonigral degeneration (parkinson variant of multiple system atrophy).
Topics: Animals; Biomarkers; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Excitatory Amino Acid Antagonists; Male; Medial Forebrain Bundle; Movement; Multiple System Atrophy; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Quinolinic Acid; Rats; Rats, Wistar; Riluzole; Substantia Nigra; Treatment Outcome | 2005 |
Serotonin 5-HT4 receptors and their mRNAs in rat and guinea pig brain: distribution and effects of neurotoxic lesions.
Topics: Adrenergic Agents; Animals; Autoradiography; Brain; Dioxanes; Guinea Pigs; Humans; Immunohistochemistry; In Situ Hybridization; Male; Neural Pathways; Neurons; Oxidopamine; Piperidines; Protein Isoforms; Quinolinic Acid; Rats; Receptors, Serotonin, 5-HT4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Antagonists; Species Specificity | 2005 |
The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development.
Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Gene Expression Regulation, Developmental; Interneurons; Neurons; Neurotoxins; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 2005 |
Pig xenografts to the immunocompetent rat brain: Survival rates using distinct neurotoxic lesions in the nigrostriatal pathway and two rat strains.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain Tissue Transplantation; Cell Size; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Fetal Tissue Transplantation; Graft Survival; Male; Neural Pathways; Neurons; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Species Specificity; Substantia Nigra; Swine; Time Factors; Transplantation, Heterologous | 2005 |
Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.
Topics: Animals; Antiparkinson Agents; Biomarkers; Calbindins; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Situ Hybridization; Isoenzymes; Neurons; Oxidopamine; Parvalbumins; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D2; S100 Calcium Binding Protein G; Selegiline; Sympatholytics; Tyrosine 3-Monooxygenase | 2005 |
Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats.
Topics: Animals; Brain Damage, Chronic; Cell Differentiation; Cell Movement; Cell Proliferation; Corpus Striatum; Doublecortin Domain Proteins; Doublecortin Protein; Environment; Locomotion; Male; Microtubule-Associated Proteins; Motor Skills; Nerve Regeneration; Neural Cell Adhesion Molecule L1; Neuronal Plasticity; Neurons; Neuropeptides; Neurotoxins; Oxidopamine; Physical Stimulation; Quinolinic Acid; Rats; Rats, Wistar; Recovery of Function; Sialic Acids; Stem Cells | 2007 |
Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy.
Topics: Animals; Apomorphine; Cell Count; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Exploratory Behavior; Female; Functional Laterality; Gait Disorders, Neurologic; Motor Activity; Multiple System Atrophy; Oxidopamine; Parkinson Disease; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2012 |
l-dopa-induced dyskinesias in unilateral 6-hydroxydopamine-lesioned rats are not modified by excitotoxic lesion of the entopeduncular nucleus and substantia nigra pars reticulata.
Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; Entopeduncular Nucleus; Levodopa; Male; Movement; Neurons; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2013 |
Why am I lost without dopamine? Effects of 6-OHDA lesion on the encoding of reward and decision process in CA3.
Topics: Action Potentials; Adrenergic Agents; Animals; Brain Injuries; CA3 Region, Hippocampal; Decision Making; Disease Models, Animal; Dopamine; Exploratory Behavior; Food Deprivation; Functional Laterality; Male; Maze Learning; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Reward | 2013 |
Unilateral medial frontal cortex lesions cause a cognitive decision-making deficit in rats.
Topics: Animals; Cognition Disorders; Decision Making; Dopamine; Frontal Lobe; Functional Laterality; Male; Mesencephalon; Motor Activity; Neuropsychological Tests; Oxidopamine; Photomicrography; Quinolinic Acid; Rats; Reward | 2014 |
A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glucose; Injections, Intraperitoneal; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Quinolinic Acid; Rats; Rats, Wistar; Striatonigral Degeneration; Touch | 2014 |
Comparing the Effects of Ferulic Acid and Sugarcane Aqueous Extract in In Vitro and In Vivo Neurotoxic Models.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Birth Rate; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Ferrous Compounds; In Vitro Techniques; Iron; Locomotion; Male; Neurotoxicity Syndromes; Oxidopamine; Plant Extracts; Quinolinic Acid; Rats; Rats, Wistar; Saccharum | 2018 |