quinolinic acid and niacin

quinolinic acid has been researched along with niacin in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199013 (30.23)18.7374
1990's12 (27.91)18.2507
2000's11 (25.58)29.6817
2010's6 (13.95)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Gallo-Mezo, MA; Moneti, G; Moroni, F; Pellicciari, R; Russi, P1
Hayakawa, T; Iwai, K; Shibata, K; Taguchi, H1
Murata, K; Shibata, K1
Fridovich, I; Gardner, PR1
Hayakawa, T; Iwai, K; Murata, K; Shibata, K1
French, ED; Schwarcz, R; Ungerstedt, U; Vezzani, A1
Butterfield, DA; Farmer, BT1
Filov, VA; Ivin, BA; Kon'kov, SA; Krylova, IM; Reztsova, VV1
Carlà, V; Carpenedo, R; Chiarugi, A; Lombardi, G; Mattoli, L; Moroni, F; Pellicciari, R; Russi, P1
Fedele, E; Foster, AC1
Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF1
Grant, RS; Kapoor, V1
Beninger, RJ; Boegman, RJ; Harris, CA; Jhamandas, K; Miranda, AF; Tanguay, JJ1
Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF; Sutton, MA1
Amici, A; Emanuelli, M; Magni, G; Raffaelli, N; Ruggieri, S1
Cleaves, HJ; Miller, SL1
Fukuwatari, T; Shibata, K; Sugimoto, E1
Fukuwatari, T; Hayakawa, F; Morikawa, Y; Shibata, K; Sugimoto, E1
Braga, O; Brew, BJ; Grant, RS; Guillemin, GJ; Kerr, SJ; Smythe, GA; Walker, DW1
Egashira, Y; Fukuoka, S; Ishiguro, K; Sanada, H; Shibata, K; Tanabe, A; Yanagihara, K1
Fukuwatari, T; Morikawa, Y; Shibata, K; Sugimoto, E1
Fukuwatari, T; Shibata, K; Sugimoto, E; Suzuki, Y1
SCARDI, V; VIRGILIO, A1
HANKES, LV; SEGEL, IH1
AURICCHIO, S; COZZOLINO, D; QUAGLIARIELLO, E; SORDINO, R1
HENDERSON, LM; WILSON, RG1
GHOLSON, RK; HENDERSON, LM; OGASAWARA, N; UEDA, I1
KONNO, K; OIZUMI, K; OKA, S; SHIMIZU, Y1
CHIBA, C; KONNO, K; OIZUMI, K; OKA, S; SHIMIZU, Y; TAMAGAWA, S1
CEDRANGOLO, F; SCARDI, V1
Fukuwatari, T; Kitamura, J; Ohta, M; Sasaki, R; Shibata, K1
Egashira, Y; Fukuoka, S; Fukuwatari, T; Ishiguro, K; Sanada, H; Shibata, K; Tanabe, A1
HENDERSON, LM1
BONNER, DM; YANOFSKY, C1
Augspurger, NR; Baker, DH1
Fukuwatari, T; Kurata, K; Shibata, K1
Gakière, B; Guérard, F; Pétriacq, P; Tcherkez, G1
Fukuoka, S; Fukuwatari, T; Nakao, N; Sano, M; Sasaki, R; Shibata, K; Terakata, M1
Blaby, IK; de Crécy-Lagard, V; De Ingeniis, J; Osterman, AL; Rodionova, IA; Sorci, L; Tkachenko, S1
Fukuwatari, T; Funakoshi, H; Kadota, E; Kanai, M; Nakamura, T; Sano, M; Shibata, K; Terakata, M1
Shibata, K1
Cater, T; Croft, T; Dhugga, G; Groth, B; James Theoga Raj, C; Lin, SJ; Venkatakrishnan, P1
Chen, J; Chen, X; He, S; Huang, Y; Li, G; Li, H; Liu, L; Meng, X; Ou, J; Zhang, W; Zhao, Z; Zhou, J1

Reviews

1 review(s) available for quinolinic acid and niacin

ArticleYear
Enzymology of NAD+ synthesis.
    Advances in enzymology and related areas of molecular biology, 1999, Volume: 73

    Topics: Amide Synthases; Amidohydrolases; Animals; Humans; NAD; Niacin; Nicotinamidase; Nicotinamide-Nucleotide Adenylyltransferase; Pentosyltransferases; Phosphotransferases (Alcohol Group Acceptor); Pyrophosphatases; Quinolinic Acid

1999

Trials

1 trial(s) available for quinolinic acid and niacin

ArticleYear
Excess dietary lysine increases growth of chicks fed niacin-deficient diets, but dietary quinolinic acid has no niacin-sparing activity.
    Poultry science, 2007, Volume: 86, Issue:2

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Lysine; Niacin; Nutritional Requirements; Quinolinic Acid; Weight Gain

2007

Other Studies

41 other study(ies) available for quinolinic acid and niacin

ArticleYear
Modulation of quinolinic and kynurenic acid content in the rat brain: effects of endotoxins and nicotinylalanine.
    Journal of neurochemistry, 1991, Volume: 57, Issue:5

    Topics: Alanine; Animals; Brain; Endotoxins; Escherichia coli; Gas Chromatography-Mass Spectrometry; Kidney; Kynurenic Acid; Lipopolysaccharides; Liver; Male; Models, Neurological; Niacin; Organ Specificity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains

1991
Regulation of pyridine nucleotide coenzyme metabolism.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Dietary Proteins; Liver; Male; NAD; Niacin; Nicotinamide Mononucleotide; Organ Specificity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains

1991
Efficiency of exogenous quinolinic acid, a metabolite of tryptophan, as a niacin precursor in rats.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Male; Niacin; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan

1991
Quinolinate phosphoribosyl transferase is not the oxygen-sensitive site of nicotinamide adenine dinucleotide biosynthesis.
    Free radical biology & medicine, 1990, Volume: 8, Issue:2

    Topics: Bacterial Proteins; Chromatography, Paper; Escherichia coli; Free Radicals; Hydrogen Peroxide; Hyperbaric Oxygenation; NAD; Niacin; Pentosyltransferases; Quinolinic Acid; Quinolinic Acids

1990
Effect of dietary orotic acid on the levels of liver and blood NAD in rats.
    Journal of nutritional science and vitaminology, 1985, Volume: 31, Issue:3

    Topics: Animals; Body Weight; Creatinine; Diet; DNA; Fats; Liver; Male; NAD; Niacin; Organ Size; Orotic Acid; Proteins; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Time Factors; Tryptophan

1985
In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures.
    Journal of neurochemistry, 1985, Volume: 45, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Electroencephalography; gamma-Aminobutyric Acid; Glutamine; Glycine; Hippocampus; Humans; Injections, Intraventricular; Male; Niacin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Taurine

1985
Quinolinic acid, an endogenous metabolite with neurotoxic properties, alters the physical state of membrane proteins in human erythrocytes.
    Life sciences, 1984, Jul-30, Volume: 35, Issue:5

    Topics: Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Membrane Proteins; Neurotoxins; Niacin; Pyridines; Quinolinic Acid; Quinolinic Acids; Spin Labels

1984
[Basic and salvage pathways of NAD biosynthesis in organs of normal rats, tumor-bearing rats and in tumors].
    Voprosy onkologii, 1994, Volume: 40, Issue:1-3

    Topics: Animals; Carcinoma 256, Walker; Enzyme Precursors; Kidney; Liver; Lymphoma, Non-Hodgkin; NAD; Neoplasms, Experimental; Niacin; Niacinamide; Quinolinic Acid; Rats

1994
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities.
    Neuroscience, 1994, Volume: 61, Issue:2

    Topics: Alanine; Animals; Anticonvulsants; Brain Chemistry; Electroshock; Excitatory Amino Acid Antagonists; Hydrolases; Hypnotics and Sedatives; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Motor Activity; Neuroglia; Niacin; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

1994
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
    Neuroscience, 1993, Volume: 52, Issue:4

    Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine

1993
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid.
    Neuroscience, 1997, Volume: 78, Issue:4

    Topics: Alanine; Animals; Corpus Striatum; Dopamine; Drug Combinations; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neurons; Neurotoxins; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase

1997
Murine glial cells regenerate NAD, after peroxide-induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates.
    Journal of neurochemistry, 1998, Volume: 70, Issue:4

    Topics: Animals; Hydrogen Peroxide; NAD; Neuroglia; Niacin; Niacinamide; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substrate Specificity

1998
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Alanine; Animals; Anticonvulsants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Antagonists; Huntington Disease; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; NADP; Neurons, Afferent; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1998
Quinolinic acid lesion of the nigrostriatal pathway: effect on turning behaviour and protection by elevation of endogenous kynurenic acid in Rattus norvegicus.
    Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2

    Topics: Alanine; Animals; Corpus Striatum; Excitatory Amino Acid Antagonists; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Motor Activity; Neurons; Neuroprotective Agents; Niacin; Parkinson Disease, Secondary; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Up-Regulation

1999
The nicotinamide biosynthetic pathway is a by-product of the RNA world.
    Journal of molecular evolution, 2001, Volume: 52, Issue:1

    Topics: Aspartic Acid; Dihydroxyacetone; Dihydroxyacetone Phosphate; Glyceraldehyde; Glyceraldehyde 3-Phosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; NAD; Niacin; Quinolinic Acid; RNA

2001
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:6

    Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain

2001
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:10

    Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency; Tryptophan; Xanthurenates

2001
Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry.
    Analytical biochemistry, 2002, Feb-01, Volume: 301, Issue:1

    Topics: Animals; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Kynurenine; Niacin; Niacinamide; Picolinic Acids; Quinolinic Acid; Sheep

2002
Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis".
    The Journal of biological chemistry, 2002, Sep-20, Volume: 277, Issue:38

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Carboxy-Lyases; COS Cells; DNA, Complementary; DNA, Recombinant; Humans; Kidney; Molecular Sequence Data; Niacin; Quinolinic Acid; Sequence Homology, Amino Acid; Swine; Tryptophan

2002
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:6

    Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orotic Acid; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Vitamin B Deficiency; Weight Gain

2002
Identification of a toxic mechanism of the plasticizers, phtahlic acid esters, which are putative endocrine disrupters: time-dependent increase in quinolinic acid and its metabolites in rats fed di(2-ethylhexyl)phthalate.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:12

    Topics: Animals; Body Weight; Carboxy-Lyases; Diethylhexyl Phthalate; Feeding Behavior; Hexanols; Liver; Niacin; Quinolinic Acid; Rats; Tryptophan

2002
[Transformation of 3-hydroxy anthramilic acid into quinolinic acid and into nicotinic acid].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:1

    Topics: Aminobenzoates; Niacin; Nicotinic Acids; Pyridines; Quinolinic Acid

1953
Synthesis and metabolism of quinolinic acid ring labeled with tritium.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 94, Issue:3

    Topics: Biochemical Phenomena; Niacin; Prostheses and Implants; Pyridines; Quinolinic Acid; Tritium

1957
[Metabolism of 3-hydroxyanthranilic acid, quinolinic acid & nicotinic acid in Escherichia coli].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Aug-31, Volume: 34, Issue:16

    Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Biochemical Phenomena; Escherichia coli; Niacin; Nicotinic Acids; Pyridines; Quinolinic Acid

1958
Tryptophan-niacin relationship in Xanthomonas pruni.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Niacin; Nicotinic Acids; Quinolinic Acid; Tryptophan; Xanthomonas

1963
THE ENZYMATIC CONVERSION OF QUINOLINATE TO NICOTINIC ACID MONONUCLEOTIDE IN MAMMALIAN LIVER.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Aniline Compounds; Animals; Carbon Isotopes; Cattle; Chromatography; Glycerol; Lactobacillus; Liver; Liver Extracts; Magnesium; Manganese; Metabolism; NAD; Niacin; Nicotinamide Mononucleotide; Nicotinic Acids; Pyridines; Quinolinic Acid; Research

1964
NIACIN METABOLISM IN MYCOBACTERIA. QUINOLINIC ACID AS A PRECURSOR OF NIACIN RIBONUCLEOTIDE AND THE DIFFERENCES IN NIACIN BIOSYNTHESIS AMONG VARIOUS SPECIES OF MYCOBACTERIA.
    The American review of respiratory disease, 1965, Volume: 91

    Topics: Metabolism; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Niacin; Nicotinamide Mononucleotide; Nicotinic Acids; Nucleotides; Pyridines; Quinolinic Acid

1965
[NIACIN METABOLISM IN MYCOBACTERIA. QUINOLINIC ACID AS A PRECURSOR OF NIACIN RIBONUCLEOTIDE AND THE DIFFERENCE IN NIACIN BIOSYNTHESIS AMONG VARIOUS SPECIES OF MYCOBACTERIA].
    Kekkaku : [Tuberculosis], 1965, Volume: 40

    Topics: Metabolism; Mycobacterium; Niacin; Nicotinic Acids; Quinolinic Acid; Research; Ribonucleotides

1965
[Quinolinic acid as a precursor of nicotinic acid].
    Bulletin de la Societe de chimie biologique, 1951, Volume: 33, Issue:9

    Topics: Niacin; Nicotinic Acids; Quinolines; Quinolinic Acid

1951
Effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in mice.
    Experimental animals, 2004, Volume: 53, Issue:1

    Topics: Analysis of Variance; Animals; Body Weights and Measures; Diet; Diethylhexyl Phthalate; Mice; Niacin; Quinolinic Acid; Tryptophan

2004
Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carboxy-Lyases; Cloning, Molecular; COS Cells; DNA, Complementary; Gene Expression; Humans; Models, Biological; Molecular Sequence Data; Niacin; Quinolinic Acid; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Tryptophan

2003
Quinolinic acid metabolism; replacement of nicotinic acid for the growth of the rat and Neurospora.
    The Journal of biological chemistry, 1949, Volume: 181, Issue:2

    Topics: Animals; Neurospora; Niacin; Nicotinic Acids; Quinolines; Quinolinic Acid; Rats

1949
Quinolinic acid accumulation in the conversion of 3-hydroxyanthranilic acid to niacin in Neurospora.
    Proceedings of the National Academy of Sciences of the United States of America, 1949, Volume: 35, Issue:10

    Topics: 3-Hydroxyanthranilic Acid; Fungi; Neurospora; Niacin; Quinolinic Acid

1949
[Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2009, Volume: 50, Issue:2

    Topics: Animals; Eating; Growth; Male; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Reference Values; Serotonin; Tryptophan; Vitamin B Complex; Weight Gain

2009
Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line.
    Plant physiology and biochemistry : PPB, 2011, Volume: 49, Issue:10

    Topics: Adenosine Triphosphate; Arabidopsis; Bacteria; Chromatography, Liquid; Magnetic Resonance Spectroscopy; NAD; Niacin; Niacinamide; Pentosyltransferases; Photosynthesis; Plant Extracts; Plant Leaves; Plants, Genetically Modified; Quinolinic Acid; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
Establishment of true niacin deficiency in quinolinic acid phosphoribosyltransferase knockout mice.
    The Journal of nutrition, 2012, Volume: 142, Issue:12

    Topics: Animals; Body Weight; Disease Models, Animal; Eating; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; Niacin; Niacinamide; Pentosyltransferases; Quinolinic Acid

2012
Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.
    Journal of bacteriology, 2013, Volume: 195, Issue:4

    Topics: Amide Synthases; Bacterial Proteins; Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Mutation; NAD; Niacin; Nicotinamide-Nucleotide Adenylyltransferase; Quinolinic Acid; Streptococcus pyogenes

2013
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
    The Journal of nutrition, 2013, Volume: 143, Issue:7

    Topics: 3-Hydroxyanthranilic Acid; Animals; Body Weight; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Niacin; Niacinamide; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates

2013
True Niacin Deficiency in Quinolinic Acid Phosphoribosyltransferase (QPRT) Knockout Mice.
    Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl

    Topics: Animals; Disease Models, Animal; Mice, Inbred C57BL; Mice, Knockout; Mutation; NAD; Niacin; Nutritional Status; Pentosyltransferases; Quinolinic Acid; Vitamin B Deficiency

2015
The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate
    The Journal of biological chemistry, 2019, 04-05, Volume: 294, Issue:14

    Topics: Animals; Copper; Mice; NAD; Niacin; Nuclear Proteins; Quinolinic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirtuin 2; Transcription Factors

2019
Urine metabolomic characteristics of female patients with occupational chronic cadmium poisoning after 15 years of treatment.
    Biomedical chromatography : BMC, 2023, Volume: 37, Issue:1

    Topics: Biomarkers; Cadmium Poisoning; Creatine; Female; Glutamic Acid; Humans; Metabolomics; Niacin; Quinolinic Acid

2023