quinolinic acid has been researched along with nad in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (13.33) | 18.7374 |
| 1990's | 10 (16.67) | 18.2507 |
| 2000's | 19 (31.67) | 29.6817 |
| 2010's | 18 (30.00) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pewnim, T; Seifert, J | 1 |
| Hayakawa, T; Iwai, K; Shibata, K; Taguchi, H | 1 |
| Fridovich, I; Gardner, PR | 1 |
| Kiyohara, Y; Sano, K; Shin, M; Shirasawa, K; Umezawa, C | 1 |
| Flachmann, R; Gassen, HG; Gütlich, M; Kunz, N; Läufer, A; Seifert, J; Wientjes, FJ | 1 |
| Hayakawa, T; Iwai, K; Murata, K; Shibata, K | 1 |
| Brougher, DS; Foster, AC; Okuno, E; Schwarcz, R | 1 |
| Dousa, TP; Kempson, SA; Ou, SY | 1 |
| Filov, VA; Ivin, BA; Kon'kov, SA; Krylova, IM; Reztsova, VV | 1 |
| Cheng, W; Roth, JR | 1 |
| Grant, RS; Kapoor, V | 1 |
| Blinder, KL; Moffett, JR; Namboodiri, MA; Venkateshan, CN | 1 |
| Brown, OR; Dang, Y; Xia, C | 1 |
| Amici, A; Emanuelli, M; Magni, G; Raffaelli, N; Ruggieri, S | 1 |
| Grant, RS; Kapoor, V; Matanovic, G; Passey, R; Smythe, G | 1 |
| Brown, OR; Dale, WE; Dang, Y | 1 |
| Cleaves, HJ; Miller, SL | 1 |
| Fukuwatari, T; Shibata, K; Sugimoto, E | 1 |
| Sanni, LA | 1 |
| Fukuwatari, T; Hayakawa, F; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| Fukuwatari, T; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| Moffett, JR; Namboodiri, MA | 1 |
| AURICCHIO, S; QUAGLIARIELLO, E; RINALDI, E; VIOLANTE, A | 1 |
| ANDREOLI, AJ; HAYAISHI, O; IKEDA, M; NISHIZUKA, Y | 1 |
| GHOLSON, RK; HENDERSON, LM; OGASAWARA, N; UEDA, I | 1 |
| Gerlt, JA | 1 |
| Anantha, S; Begley, TP; Colabroy, K; Gerdes, S; Goral, V; Kurnasov, O; Osterman, A | 1 |
| Fukuwatari, T; Sasaki, R; Shibata, K; Wada, H | 1 |
| Begley, TP; Colabroy, KL | 1 |
| Akita, M; Hashimoto, T; Katoh, A; Uenohara, K | 1 |
| Gakière, B; Noctor, G; Queval, G | 1 |
| Darlington, LG; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N | 1 |
| Lee, JK; Rozenberg, A | 1 |
| Ashihara, H; Matsui, A; Sakuta, M; Yin, Y | 1 |
| Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D | 1 |
| Ashihara, H; Katahira, R | 1 |
| Galeazzi, L; Garavaglia, S; Perozzi, S; Raffaelli, N; Rizzi, M | 1 |
| Adams, S; Braidy, N; Grant, R; Guillemin, GJ | 1 |
| Gakière, B; Guérard, F; Pétriacq, P; Tcherkez, G | 1 |
| de Bont, L; Didierlaurent, L; Gakière, B; Guérard, F; Hager, J; Mauve, C; Noctor, G; Pelletier, S; Pétriacq, P; Renou, JP; Tcherkez, G | 1 |
| Fukuoka, S; Fukuwatari, T; Nakao, N; Sano, M; Sasaki, R; Shibata, K; Terakata, M | 1 |
| Blaby, IK; de Crécy-Lagard, V; De Ingeniis, J; Osterman, AL; Rodionova, IA; Sorci, L; Tkachenko, S | 1 |
| Kawai, S; Murata, K; Ohashi, K | 1 |
| Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W | 1 |
| Fukuwatari, T; Morita, N; Shibata, K; Shibata, Y | 1 |
| Kumar, A; Mishra, J | 1 |
| Bertuch, AA; Polleys, EJ | 1 |
| Couté, Y; Ollagnier de Choudens, S; Reichmann, D | 1 |
| Shibata, K | 1 |
| Muramoto, K; Nakagawa, S; Ogawa, T; Shigeoka, S; Takada, R; Yoshimura, K | 1 |
| Armstrong, SK; Brickman, TJ; McKelvey, PJ; Suhadolc, RJ | 1 |
| Hanna-Rose, W; Holleran, LM; McReynolds, MR; Wang, W | 1 |
| Amara, P; Darnault, C; Fontecilla-Camps, JC; Gigarel, O; Hamelin, O; Han, TH; Ollagnier-de-Choudens, S; Renoux, O; Saez Cabodevilla, J; Volbeda, A | 1 |
| Adams, S; Castellano-Gonzalez, G; Cole, NJ; Don, E; Guillemin, GJ; Jacobs, KR; Lim, CK; Lovejoy, DB | 1 |
| Cater, T; Croft, T; Dhugga, G; Groth, B; James Theoga Raj, C; Lin, SJ; Venkatakrishnan, P | 1 |
| Arun, P; Badawy, AA; Ives, JA; Moffett, JR; Namboodiri, AM; Puthillathu, N; Vengilote, R | 1 |
| Hanasaki, M; Masumoto, H; Nakagawa, T; Yaku, K; Yamauchi, M | 1 |
| Chen, Y; Ding, Y; Horsman, GP; Li, J; Li, P; Li, X; Liu, W; Tao, Y; Wang, M; Wu, B; Zhang, Z | 1 |
| Anglicheau, D; Bignon, Y; Cippà, PE; Fohlen, B; Galichon, P; Hertig, A; Karras, A; Lenoir, O; Nadour, Z; Naesens, M; Nemazanyy, I; Pallet, N; Poindessous, V; Rinaldi, A; Weill-Raynal, P | 1 |
| Ciampa, EJ; Clark, AJ; Etzrodt, V; Flores, BM; Huang, H; Parikh, SM; Saade, MC; Takakura, A; Vemireddy, V; Vu, KQ; Zandi-Nejad, K; Zsengellér, ZK | 1 |
5 review(s) available for quinolinic acid and nad
| Article | Year |
|---|---|
Enzymology of NAD+ synthesis.
Topics: Amide Synthases; Amidohydrolases; Animals; Humans; NAD; Niacin; Nicotinamidase; Nicotinamide-Nucleotide Adenylyltransferase; Pentosyltransferases; Phosphotransferases (Alcohol Group Acceptor); Pyrophosphatases; Quinolinic Acid | 1999 |
Tryptophan and the immune response.
Topics: Animals; Dendritic Cells; Dioxygenases; Humans; Immune System; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; NAD; Oxygenases; Poly(ADP-ribose) Polymerases; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 2003 |
NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.
Topics: Amino Acid Sequence; Cell Compartmentation; Molecular Sequence Data; NAD; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Plants; Quinolinic Acid; Sequence Homology, Amino Acid | 2006 |
Tryptophan, adenosine, neurodegeneration and neuroprotection.
Topics: Adenosine; Animals; Hepatic Encephalopathy; Humans; Kynurenine; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Tryptophan | 2007 |
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan | 2009 |
55 other study(ies) available for quinolinic acid and nad
| Article | Year |
|---|---|
Alteration of mice L-tryptophan metabolism by the organophosphorous acid triester diazinon.
Topics: Animals; Arylformamidase; Diazinon; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Models, Biological; NAD; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1992 |
Regulation of pyridine nucleotide coenzyme metabolism.
Topics: Animals; Dietary Proteins; Liver; Male; NAD; Niacin; Nicotinamide Mononucleotide; Organ Specificity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Quinolinate phosphoribosyl transferase is not the oxygen-sensitive site of nicotinamide adenine dinucleotide biosynthesis.
Topics: Bacterial Proteins; Chromatography, Paper; Escherichia coli; Free Radicals; Hydrogen Peroxide; Hyperbaric Oxygenation; NAD; Niacin; Pentosyltransferases; Quinolinic Acid; Quinolinic Acids | 1990 |
Tryptophan metabolism by the isolated rat liver cells--effects of leucine and its metabolites.
Topics: Acetoacetates; Animals; In Vitro Techniques; Keto Acids; Leucine; Liver; NAD; Pentosyltransferases; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1989 |
Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA Restriction Enzymes; Escherichia coli; Escherichia coli Proteins; Genes; Genes, Bacterial; Molecular Sequence Data; NAD; Plasmids; Promoter Regions, Genetic; Pyridines; Quinolinic Acid; Quinolinic Acids | 1988 |
Effect of dietary orotic acid on the levels of liver and blood NAD in rats.
Topics: Animals; Body Weight; Creatinine; Diet; DNA; Fats; Liver; Male; NAD; Niacin; Organ Size; Orotic Acid; Proteins; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Time Factors; Tryptophan | 1985 |
A radioenzymatic assay for quinolinic acid.
Topics: Adult; Humans; Male; NAD; Nicotinamide Mononucleotide; Pentosyltransferases; Pyridines; Quinolinic Acid; Quinolinic Acids; Tritium | 1986 |
Relationship between rate of gluconeogenesis and content of nicotinamide adenine dinucleotide in renal cortex.
Topics: Animals; Cytosol; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Ketoglutaric Acids; Kidney Cortex; Kinetics; Male; NAD; Picolinic Acids; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1981 |
[Basic and salvage pathways of NAD biosynthesis in organs of normal rats, tumor-bearing rats and in tumors].
Topics: Animals; Carcinoma 256, Walker; Enzyme Precursors; Kidney; Liver; Lymphoma, Non-Hodgkin; NAD; Neoplasms, Experimental; Niacin; Niacinamide; Quinolinic Acid; Rats | 1994 |
Evidence for two NAD kinases in Salmonella typhimurium.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Culture Media; Genes, Bacterial; Mutagenesis; NAD; NADP; Phosphotransferases (Alcohol Group Acceptor); Quinolinic Acid; Salmonella typhimurium; Temperature | 1994 |
Murine glial cells regenerate NAD, after peroxide-induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates.
Topics: Animals; Hydrogen Peroxide; NAD; Neuroglia; Niacin; Niacinamide; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substrate Specificity | 1998 |
Differential effects of kynurenine and tryptophan treatment on quinolinate immunoreactivity in rat lymphoid and non-lymphoid organs.
Topics: Animals; Immunohistochemistry; Injections, Intraperitoneal; Kynurenine; Lymphoid Tissue; Male; NAD; Organ Specificity; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan | 1998 |
HPLC analysis of quinolinic acid, a NAD biosynthesis intermediate, after fluorescence derivatization in an aqueous matrix.
Topics: Cadaverine; Chromatography, High Pressure Liquid; Fluorescent Dyes; NAD; Quinolinic Acid; Sensitivity and Specificity; Water | 1998 |
Evidence for increased de novo synthesis of NAD in immune-activated RAW264.7 macrophages: a self-protective mechanism?
Topics: Animals; Benzamides; Cell Line; Dexamethasone; Enzyme Inhibitors; Interferon-gamma; Macrophage Activation; Macrophages; Mice; NAD; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide Synthase; Poly(ADP-ribose) Polymerase Inhibitors; Quinolinic Acid; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase | 1999 |
Tryptophan metabolism through the kynurenine pathway in rat brain and liver slices.
Topics: Aerobiosis; Animals; Brain; In Vitro Techniques; Kynurenine; Liver; Male; NAD; Organ Specificity; Oxygen; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan | 2000 |
The nicotinamide biosynthetic pathway is a by-product of the RNA world.
Topics: Aspartic Acid; Dihydroxyacetone; Dihydroxyacetone Phosphate; Glyceraldehyde; Glyceraldehyde 3-Phosphate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; NAD; Niacin; Quinolinic Acid; RNA | 2001 |
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain | 2001 |
The role of cerebral oedema in the pathogenesis of cerebral malaria.
Topics: Adult; Africa; Animals; Asia, Southeastern; Blood-Brain Barrier; Brain Edema; Cell Adhesion; Cerebrovascular Circulation; Child; Cytokines; Energy Metabolism; Humans; Hypoxia-Ischemia, Brain; Indoleamine-Pyrrole 2,3,-Dioxygenase; Malaria; Malaria, Cerebral; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Biological; NAD; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plasmodium berghei; Quinolinic Acid; Tryptophan Oxygenase; Vasodilation | 2001 |
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency; Tryptophan; Xanthurenates | 2001 |
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orotic Acid; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Vitamin B Deficiency; Weight Gain | 2002 |
On the effect of DPN on the conversion of 3-hydroxyanthranilic acid to quinolinic acid in presence of hepatic tissue of rats affected by Oberling's myeloma in the leukemic phase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Coenzymes; Leukemia; Leukemia, Myeloid; Liver; Multiple Myeloma; NAD; Pyridines; Quinolinic Acid; Rats | 1958 |
Quinolinic acid: a precursor to nicotinamide adenine dinucleotide in Escherichia coli.
Topics: Escherichia coli; Humans; NAD; Pyridines; Quinolinic Acid | 1963 |
THE ENZYMATIC CONVERSION OF QUINOLINATE TO NICOTINIC ACID MONONUCLEOTIDE IN MAMMALIAN LIVER.
Topics: Aniline Compounds; Animals; Carbon Isotopes; Cattle; Chromatography; Glycerol; Lactobacillus; Liver; Liver Extracts; Magnesium; Manganese; Metabolism; NAD; Niacin; Nicotinamide Mononucleotide; Nicotinic Acids; Pyridines; Quinolinic Acid; Research | 1964 |
How to find "missing" genes.
Topics: Bacteria; Bacterial Proteins; Genes, Bacterial; Genome, Bacterial; Genomics; Molecular Structure; NAD; Quinolinic Acid | 2003 |
NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria.
Topics: Arylformamidase; Bacteria; Chromosomes, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Hydrolases; Kinetics; Molecular Sequence Data; NAD; Oxidoreductases; Quinolinic Acid; Tryptophan | 2003 |
Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.
Topics: Animals; Dose-Response Relationship, Drug; Eating; Liver; Male; NAD; NADP; Niacinamide; Nicotinic Acids; Predictive Value of Tests; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain | 2004 |
The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Dicarboxylic Acids; Dioxygenases; NAD; Nuclear Magnetic Resonance, Biomolecular; Pyridines; Quinolinic Acid | 2005 |
Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid.
Topics: Amino Acid Oxidoreductases; Arabidopsis; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Multienzyme Complexes; NAD; Pentosyltransferases; Plastids; Quinolinic Acid | 2006 |
Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.
Topics: Carbon; Carbon Dioxide; Chemistry, Organic; Computational Biology; Decarboxylation; Models, Chemical; Models, Theoretical; NAD; Nicotinamide Mononucleotide; Orotidine-5'-Phosphate Decarboxylase; Quinolinic Acid; Software; Solvents; Thermodynamics | 2008 |
Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures.
Topics: Alkaloids; Carbon Radioisotopes; Cells, Cultured; Gene Expression Regulation, Plant; Lotus; NAD; Niacinamide; Nicotinamidase; Plant Proteins; Pyridines; Quinolinic Acid; Time Factors; Tritium | 2008 |
Profiles of the biosynthesis and metabolism of pyridine nucleotides in potatoes (Solanum tuberosum L.).
Topics: Carbon Isotopes; NAD; Niacinamide; Nucleotides; Organ Specificity; Plant Leaves; Plant Tubers; Quinolinic Acid; Solanum tuberosum; Time Factors; Tissue Extracts; Tritium | 2009 |
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis.
Topics: Carboxy-Lyases; Crystallography, X-Ray; Dihydroxyacetone Phosphate; Glycolysis; Humans; NAD; Picolinic Acids; Protein Binding; Quinolinic Acid; Signal Transduction | 2009 |
Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.
Topics: Apigenin; Calcium Signaling; Catechin; Cells, Cultured; Curcumin; Enzyme Activation; Flavanones; Flavonoids; Humans; Hydrolyzable Tannins; L-Lactate Dehydrogenase; NAD; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Phenols; Poly(ADP-ribose) Polymerases; Polyphenols; Quinolinic Acid; Tyrosine | 2010 |
Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line.
Topics: Adenosine Triphosphate; Arabidopsis; Bacteria; Chromatography, Liquid; Magnetic Resonance Spectroscopy; NAD; Niacin; Niacinamide; Pentosyltransferases; Photosynthesis; Plant Extracts; Plant Leaves; Plants, Genetically Modified; Quinolinic Acid; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Inducible NAD overproduction in Arabidopsis alters metabolic pools and gene expression correlated with increased salicylate content and resistance to Pst-AvrRpm1.
Topics: Arabidopsis; Cluster Analysis; Disease Resistance; Escherichia coli Proteins; Gene Expression Regulation, Plant; Host-Pathogen Interactions; Metabolome; NAD; Oligonucleotide Array Sequence Analysis; Pentosyltransferases; Plant Diseases; Plant Leaves; Plants, Genetically Modified; Pseudomonas syringae; Quinolinic Acid; Reverse Transcriptase Polymerase Chain Reaction; Salicylates; Transcriptome; Transgenes | 2012 |
Establishment of true niacin deficiency in quinolinic acid phosphoribosyltransferase knockout mice.
Topics: Animals; Body Weight; Disease Models, Animal; Eating; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; Niacin; Niacinamide; Pentosyltransferases; Quinolinic Acid | 2012 |
Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.
Topics: Amide Synthases; Bacterial Proteins; Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Mutation; NAD; Niacin; Nicotinamide-Nucleotide Adenylyltransferase; Quinolinic Acid; Streptococcus pyogenes | 2013 |
Secretion of quinolinic acid, an intermediate in the kynurenine pathway, for utilization in NAD+ biosynthesis in the yeast Saccharomyces cerevisiae.
Topics: Biosynthetic Pathways; Culture Media, Conditioned; Gene Expression; Gene Knockout Techniques; Genes, Fungal; Kynurenine; Membrane Transport Proteins; Microbial Viability; NAD; Pentosyltransferases; Quinolinic Acid; Saccharomyces cerevisiae; Transcription, Genetic | 2013 |
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Microglia; NAD; Oxidative Stress; Pentosyltransferases; Quinolinic Acid; Temozolomide; Tryptophan; Tryptophan Oxygenase | 2013 |
Enzymes that control the conversion of L-tryptophan-nicotinamide and the urinary excretion ratio (N(1)-methyl-2-pyridone-5-carboxamide + N(1)-methyl-4-pyridone-3-carboxamide)/N(1)-methylnicotinamide in mice.
Topics: Animals; Body Weight; Eating; Enzymes; Male; Mice; NAD; Niacinamide; Pyridones; Quinolinic Acid; Tryptophan | 2013 |
Improvement of mitochondrial NAD(+)/FAD(+)-linked state-3 respiration by caffeine attenuates quinolinic acid induced motor impairment in rats: implications in Huntington's disease.
Topics: Animals; Antioxidants; Caffeine; Cell Respiration; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Flavin-Adenine Dinucleotide; Huntington Disease; Mitochondria; NAD; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Quinolinic Acid; Rats | 2014 |
Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Bleomycin; DNA Damage; DNA Repair; Galactose; Mechanistic Target of Rapamycin Complex 1; Membrane Proteins; Multiprotein Complexes; NAD; Quinolinic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Telomere; TOR Serine-Threonine Kinases; Tryptophan | 2015 |
Dual activity of quinolinate synthase: triose phosphate isomerase and dehydration activities play together to form quinolinate.
Topics: Aspartic Acid; Bacterial Proteins; Dihydroxyacetone Phosphate; Metabolic Networks and Pathways; Models, Chemical; Multienzyme Complexes; NAD; Quinolinic Acid; Thermotoga maritima; Triose-Phosphate Isomerase | 2015 |
True Niacin Deficiency in Quinolinic Acid Phosphoribosyltransferase (QPRT) Knockout Mice.
Topics: Animals; Disease Models, Animal; Mice, Inbred C57BL; Mice, Knockout; Mutation; NAD; Niacin; Nutritional Status; Pentosyltransferases; Quinolinic Acid; Vitamin B Deficiency | 2015 |
Modulation of NADH Levels by Arabidopsis Nudix Hydrolases, AtNUDX6 and 7, and the Respective Proteins Themselves Play Distinct Roles in the Regulation of Various Cellular Responses Involved in Biotic/Abiotic Stresses.
Topics: Arabidopsis; Arabidopsis Proteins; Ascorbic Acid; Estrogens; Gene Expression Regulation, Plant; Genes, Plant; Mutation; NAD; Nudix Hydrolases; Oxidative Stress; Paraquat; Plants, Genetically Modified; Poly Adenosine Diphosphate Ribose; Pyrophosphatases; Quinolinic Acid; Salicylic Acid; Stress, Physiological | 2016 |
Essential role of Bordetella NadC in a quinolinate salvage pathway for NAD biosynthesis.
Topics: Bacterial Proteins; Biosynthetic Pathways; Bordetella; Genes, Bacterial; Mutation; NAD; Pentosyltransferases; Quinolinic Acid | 2017 |
Uridine monophosphate synthetase enables eukaryotic
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Multienzyme Complexes; Mutation; NAD; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Quinolinic Acid; Tryptophan | 2017 |
Crystallographic Trapping of Reaction Intermediates in Quinolinic Acid Synthesis by NadA.
Topics: Crystallography, X-Ray; Molecular Docking Simulation; Multienzyme Complexes; NAD; Protein Conformation; Quinolinic Acid; Thermotoga maritima | 2018 |
Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.
Topics: Adenosine Triphosphate; Brain; Cell Survival; HEK293 Cells; Humans; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; NAD; Neurons; Oxidative Stress; Primary Cell Culture; Quinolinic Acid; Reactive Oxygen Species | 2019 |
The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate
Topics: Animals; Copper; Mice; NAD; Niacin; Nuclear Proteins; Quinolinic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirtuin 2; Transcription Factors | 2019 |
Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD
Topics: Animals; Biomarkers; Cell Movement; Gerbillinae; Hippocampus; HSP90 Heat-Shock Proteins; Immunity; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Pokeweed Mitogens; Poly(ADP-ribose) Polymerases; Quinolinic Acid; Rats; Spleen; Tryptophan | 2020 |
Deletion of the GAPDH gene contributes to genome stability in Saccharomyces cerevisiae.
Topics: Acetylation; Chromosomes, Fungal; DNA Damage; DNA Replication; Gene Deletion; Genomic Instability; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; NAD; Quinolinic Acid; Saccharomyces cerevisiae | 2020 |
Construction of an Alternative NAD
Topics: Biochemical Phenomena; Cells, Cultured; Chorismic Acid; Escherichia coli; NAD; Quinolinic Acid | 2021 |
Cell stress response impairs de novo NAD+ biosynthesis in the kidney.
Topics: Acute Kidney Injury; Animals; Cell Line; Endoplasmic Reticulum Stress; Kidney; Male; Mice; Mice, Inbred C57BL; NAD; Pentosyltransferases; Quinolinic Acid; Tryptophan | 2022 |
Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury.
Topics: Acute Kidney Injury; Animals; Hepatocyte Nuclear Factors; Kidney; Mice; NAD; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Quinolinic Acid; Tryptophan | 2023 |