quinolinic acid and n-methylaspartate

quinolinic acid has been researched along with n-methylaspartate in 101 studies

Research

Studies (101)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (33.66)	18.7374
1990's	37 (36.63)	18.2507
2000's	23 (22.77)	29.6817
2010's	7 (6.93)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Beninger, RJ; Boegman, RJ; Cockhill, J; Jhamandas, K	1
Parks, TN; Zhou, N	1
Connick, JH; Stone, TW	2
Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ	1
Beaton, JA; Monaghan, DT	1
Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P	1
Rigor, BM; Schurr, A; West, CA	1
Curry, K; McLarnon, JG	1
Khaspekov, LG; Lisý, V; Stastný, F; Viktorov, IV	1
Sagar, SM	1
Khaspekov, LG; Kida, E; Mossakovski, M; Viktorov, IV	1
Jhamandas, K; Ruzicka, BB	1
Choi, DW; Hartley, DM; Koh, J; Weiss, JH	1
Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ	1
Meguri, H; Ogita, K; Ohgaki, T; Uchida, S; Yoneda, Y	1
Choi, DW; Koh, JY	1
Klockgether, T; Lehmann, J; Schwarz, M; Sontag, KH; Turski, L	1
Collins, JF; Meldrum, BS; Turski, L	1
Cotman, CW; Ganong, AH	1
Curry, K; Magnuson, DS; McLennan, H; Peet, MJ	2
Addae, JI; Stone, TW	2
Choi, DW; Koh, JY; Peters, S	1
Stone, TW	1
Lodge, D; Martin, D	1
Choi, DW; Koh, J; Peters, S	1
Davies, SW; Roberts, PJ	1
Lees, GJ	1
Samanin, R; Vezzani, A; Wu, HQ	1
Burton, NR; Smith, DA; Stone, TW	2
Burton, NR; Smith, DA; Stone, TW; Williams, TL	1
Foster, AC; Gill, R; Woodruff, GN	1
Hankins, MW; Ruddock, KH	1
Farley, JM; Huang, HM; Jin, C; Rockhold, RW	1
Garthwaite, G; Garthwaite, J	1
Carroll, BL; Crowley, WR; Johnson, MD; Whetsell, WO	1
Herrling, PL; Klockgether, T; Sontag, KH; Turski, L; Watkins, JC	1
Choi, DW; Peters, S; Viseskul, V	1
McLennan, H	1
Perkins, MN; Stone, TW	4
Herrling, PL; Morris, R; Salt, TE	1
Beninger, RJ; Boegman, RJ; Connop, BP; Jhamandas, K	1
Kent, G; Liu, JL; Papachristou, DN; Patel, SC; Patel, YC; Warszynska, A	1
Keilhoff, G; Wolf, G	1
Grigor'ev, VV	1
Altemus, KL; Cepeda, C; Colwell, CS; Levine, MS	1
Friedemann, MN; Gerhardt, GA	1
Bochet, P; de Carvalho, LP; Rossier, J	1
Altemus, KL; Colwell, CS; Levine, MS	1
Beninger, RJ; Boegman, RJ; Flesher, S; Jhamandas, KH; Pawley, AC	1
Alexi, T; Hughes, PE; Knusel, B; Schreiber, SS; Yoshida, T	1
Lees, GJ; Leong, W	1
Inglis, WL; Semba, K	1
Beninger, RJ; Boegman, RJ; Jhamandas, K; Miranda, AF	1
Ordaz-Moreno, J; Ríos, C; Rubio-Osornio, M; Santamaría, A; Solís-Hernández, F	1
Basile, AS; Fossom, L; Goping, G; Sei, Y; Skolnick, P	1
Lapin, IP; Mirzaev, SM; Oxenkrug, GF; Ryzov, IV	1
Beskid, M; Rózycka, Z; Taraszewska, A	2
Chiarugi, A; Moroni, F	1
Battaglia, G; Bruno, V; Flor, PJ; Gasparini, F; Hess, SD; Inderbitzin, W; Johnson, EC; Kuhn, R; Laurie, D; Leonhardt, T; Lukic, S; Nicoletti, F; Portet, C; Sauer, D; Schmutz, M; Sommer, B; Urwyler, S; Varney, MA	1
Brum, LF; Elisabetsky, E; Souza, DO	1
Brundin, P; Castilho, RF; Hansson, O; Leist, M; Nicotera, P; Petersén, A	1
Chen, Q; Reiner, A; Surmeier, DJ	1
Guidetti, P; Schwarcz, R	1
Obrenovitch, TP; Urenjak, J	2
Addae, JI; Stone, TW; Youssef, F	1
Feligioni, M; Pattarini, R; Pittaluga, A; Raiteri, M	1
Alsdorf, SA; Orlando, LR; Penney, JB; Young, AB	1
Lisý, V; Stastný, F	1
Schauwecker, PE	1
Akaike, A; Katsuki, H	1
Kumar, U	2
De Berardinis, MA; Domenici, MR; Frank, C; Grieco, R; Martire, A; Massotti, M; Minghetti, L; Nazzicone, V; Pepponi, R; Pèzzola, A; Pintor, A; Popoli, P; Potenza, RL; Reggio, R; Tebano, MT	1
Domenici, MR; Frank, C; Grieco, R; Martire, A; Pepponi, R; Pintor, A; Popoli, P; Potenza, RL; Tebano, MT	1
Boeck, CR; Ganzella, M; Lottermann, A; Vendite, D	1
Rho, JM	1
Cano, J; Machado, A; Rite, I; Venero, JL	1
Bari, F; Busija, DW; Domoki, F; Guidetti, P; Nagy, K; Schwarcz, R	1
Bertram, L; Bissada, N; Deng, Y; Doty, CN; Graham, RK; Haigh, B; Hayden, MR; Leavitt, BR; Lu, G; Murphy, Z; Nicholson, DW; Pearson, J; Raymond, LA; Roy, S; Shehadeh, J; Slow, EJ; Warby, SC; Wellington, CL	1
Guidetti, P; Poeggeler, B; Rassoulpour, A; Roberts, RC; Schwarcz, R; Wu, HQ	1
Boeck, CR; Dafre, AL; de Araújo Herculano, B; Franco, JL; Tasca, CI; Vandresen-Filho, S	1
Foong, N; Hong, NS; King, AL; McDonald, RJ; Rizos, Z	1
André, VM; Deng, Y; Figueroa, BE; Friedlander, R; Graham, RK; Hayden, MR; Joshi, P; Leavitt, BR; Levine, MS; Lu, G; Metzler, M; Pouladi, MA; Raymond, L; Slow, EJ; Wu, NP	1
Chen, Y; Guillemin, GJ; Meininger, V	1
Bissada, N; Gan, L; Graham, RK; Hayden, MR; Leavitt, BR; Liu, L; Lu, G; Mazarei, G; Metzler, M	1
Boeck, CR; de Araújo Herculano, B; Martins, WC; Tasca, CI; Vandresen-Filho, S	1
André, VM; Cepeda, C; Cummings, DM; Ehrlich, ME; Kim, SH; Levine, MS; Thomas, CA	1
Muller, Gdo A; Severino, PC; Tasca, CI; Vandresen-Filho, S	1
Boeck, CC; de Lima, TC; Duarte, FS; Duzzioni, M; Herculano, BA; Hoeller, AA; Marino-Neto, J; Piermartiri, TC; Tasca, CI; Vandresen-Filho, S	1
Bertoldo, DB; Constantino, LC; Dal-Cim, T; Martins, WC; Molz, S; Severino, PC; Silva, FR; Tasca, CI; Vandresen-Filho, S	1
Biasibetti-Brendler, H; Ferreira, F; Pessoa-Pureur, R; Pierozan, P; Schmitz, F; Wyse, ATS	1

Reviews

4 review(s) available for quinolinic acid and n-methylaspartate

Article	Year
Effects of quinolinic and kynurenic acids on central neurons. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: Action Potentials; Animals; Brain; Convulsants; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; Models, Neurological; N-Methylaspartate; Neurons; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission	1991
Excitatory receptors and their role in excitotoxicity. Biochemical Society transactions, 1987, Volume: 15, Issue:2 Topics: Aminobutyrates; Animals; Aspartic Acid; Brain; Glutamates; Glutamic Acid; Humans; N-Methylaspartate; Neurons; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1987
Basic science behind the catastrophic epilepsies. Epilepsia, 2004, Volume: 45 Suppl 5 Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Corticotropin-Releasing Hormone; Epilepsies, Myoclonic; Epilepsy; Humans; Infant; Infant, Newborn; Kynurenic Acid; Kynurenine; N-Methylaspartate; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Spasms, Infantile; Tryptophan	2004
Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid. Life sciences, 2011, Oct-10, Volume: 89, Issue:15-16 Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Ischemic Preconditioning; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Seizures; Signal Transduction	2011

Other Studies

97 other study(ies) available for quinolinic acid and n-methylaspartate

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Excitotoxic lesions of rat basal forebrain: differential effects on choline acetyltransferase in the cortex and amygdala. Neuroscience, 1992, Volume: 51, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Prosencephalon; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley	1992
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis). Brain research. Developmental brain research, 1992, Jun-19, Volume: 67, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission	1992
Neurochemical characterization of excitotoxin lesions in the cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1991
Quinolinate differentiates between forebrain and cerebellar NMDA receptors. European journal of pharmacology, 1991, Feb-26, Volume: 194, Issue:1 Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kinetics; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats	1991
Neurotoxicity of quinolinic acid and its derivatives in hypoxic rat hippocampal slices. Brain research, 1991, Dec-24, Volume: 568, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dose-Response Relationship, Drug; Hippocampus; Hypoxia; In Vitro Techniques; Magnesium; Male; Molecular Structure; N-Methylaspartate; Neurotoxins; Picolinic Acids; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1991
Quinolinate activation of N-methyl-D-aspartate ion channels in rat hippocampal neurons. Neuroscience letters, 1990, Aug-24, Volume: 116, Issue:3 Topics: Animals; Hippocampus; Ion Channels; N-Methylaspartate; Neurons; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Temperature	1990
Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons. Journal fur Hirnforschung, 1990, Volume: 31, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dipeptides; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Pregnancy; Quinolinic Acid; Quinolinic Acids	1990
NADPH-diaphorase reactive neurons of the rabbit retina: differential sensitivity to excitotoxins and unusual morphologic features. The Journal of comparative neurology, 1990, Oct-15, Volume: 300, Issue:3 Topics: Animals; Eye Proteins; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Rabbits; Retina; Vitreous Body	1990
[Comparative analysis of cytotoxic action of quinolinic acid and N-methyl-D-aspartate on cultured hippocampal neurons]. Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 110, Issue:9 Topics: Animals; Cells, Cultured; Dendrites; Hippocampus; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Synapses	1990
Elevation of Met-enkephalin-like immunoreactivity in the rat striatum and globus pallidus following the focal injection of excitotoxins. Brain research, 1990, Dec-17, Volume: 536, Issue:1-2 Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Globus Pallidus; Huntington Disease; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains	1990
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity. Science (New York, N.Y.), 1990, Mar-23, Volume: 247, Issue:4949 Pt 1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium Channels; Drug Antagonism; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Mice; N-Methylaspartate; Neurons; Nifedipine; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse (New York, N.Y.), 1989, Volume: 3, Issue:1 Topics: Animals; Aspartic Acid; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptide Y; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Somatostatin	1989
N-methyl-D-aspartate-sensitive [3H]glutamate binding sites in brain synaptic membranes treated with Triton X-100. Biochimica et biophysica acta, 1989, Jun-15, Volume: 1012, Issue:1 Topics: Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Kinetics; Kynurenic Acid; N-Methylaspartate; Octoxynol; Polyethylene Glycols; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes; Temperature; Tissue Distribution	1989
Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists. Brain research, 1988, Apr-19, Volume: 446, Issue:2 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Aspartic Acid; Cells, Cultured; Corpus Striatum; Embryo, Mammalian; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1988
Paradoxical convulsant action of a novel non-competitive N-methyl-D-aspartate (NMDA) antagonist, tiletamine. Brain research, 1988, Oct-04, Volume: 461, Issue:2 Topics: Animals; Anticonvulsants; Aspartic Acid; Cyclohexanes; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex, Monosynaptic; Seizures; Tiletamine	1988
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist? Brain research, 1985, Jun-10, Volume: 336, Issue:1 Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism	1985
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin	1986
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine	1986
Effects of topically applied excitatory amino acids on evoked potentials and single cell activity in rat cerebral cortex. European journal of pharmacology, 1986, Mar-04, Volume: 121, Issue:3 Topics: Administration, Topical; Amino Acids; Animals; Aspartic Acid; Carbachol; Cerebral Cortex; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tetrodotoxin	1986
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science (New York, N.Y.), 1986, Oct-03, Volume: 234, Issue:4772 Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1986
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices. Brain research, 1986, Aug-27, Volume: 381, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1986
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation. Neuroscience letters, 1987, Mar-31, Volume: 75, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine	1987
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons. Science (New York, N.Y.), 1987, May-01, Volume: 236, Issue:4801 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc	1987
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus. Neuroscience letters, 1987, Jul-22, Volume: 78, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1987
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors. Journal of neurochemistry, 1987, Volume: 49, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin	1987
The mouse neocortical slice: preparation and responses to excitatory amino acids. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 88, Issue:1 Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Cerebral Cortex; Corpus Callosum; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Inbred Strains; N-Methylaspartate; Ouabain; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Tetrodotoxin	1987
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro. British journal of pharmacology, 1988, Volume: 93, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine	1988
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo. British journal of pharmacology, 1988, Volume: 93, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine	1988
Kynurenic acid and AP5 distinguish between NMDA receptor agonists. Experimental neurology, 1988, Volume: 102, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine	1988
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors	1988
Neuropharmacological actions of kynurenic and quinolinic acids on horizontal cells of the isolated fish retina. Brain research, 1986, Aug-20, Volume: 380, Issue:2 Topics: Animals; Aspartic Acid; Cobalt; Cyprinidae; Evoked Potentials, Visual; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Photic Stimulation; Pyridines; Quinolinic Acid; Quinolinic Acids; Retina	1986
Acute tachycardia and pressor effects following injections of kainic acid into the antero-dorsal medial hypothalamus. Neuropharmacology, 1987, Volume: 26, Issue:6 Topics: Animals; Aspartic Acid; Blood Pressure; Heart Rate; Hypothalamus; Injections; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains	1987
Quinolinate mimics neurotoxic actions of N-methyl-D-aspartate in rat cerebellar slices. Neuroscience letters, 1987, Aug-18, Volume: 79, Issue:1-2 Topics: Animals; Aspartic Acid; Cerebellum; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats	1987
Interactions between topically applied excitatory amino acids on rat cerebral cortex: discrimination by pentobarbitone. Experimental brain research, 1987, Volume: 68, Issue:3 Topics: Administration, Topical; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Oxadiazoles; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains	1987
The action of quinolinate in the rat spinal cord in vitro. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:12 Topics: Animals; Anticonvulsants; Aspartic Acid; Convulsants; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord	1987
Quinolinic acid stimulates luteinizing hormone secretion through a serotonin-dependent mechanism. Experimental brain research, 1985, Volume: 59, Issue:1 Topics: Animals; Aspartic Acid; Castration; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; Norepinephrine; Pituitary Gland, Anterior; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission	1985
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents. Neuroscience letters, 1987, Jan-14, Volume: 73, Issue:2 Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Muscle Relaxants, Central; N-Methylaspartate; Oxadiazoles; Piperazines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Time Factors	1987
Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2 Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Kainic Acid; Levorphanol; Mice; Morphinans; N-Methylaspartate; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1987
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat. Neuroscience letters, 1984, May-04, Volume: 46, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine	1984
An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain research, 1982, Sep-09, Volume: 247, Issue:1 Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Convulsants; Drug Interactions; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Niacinamide; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats	1982
Actions of excitatory amino acids and kynurenic acid in the primate hippocampus: a preliminary study. Neuroscience letters, 1984, Dec-21, Volume: 52, Issue:3 Topics: Amino Acids; Animals; Aspartic Acid; Callitrichinae; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1984
Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2 Topics: Animals; Aspartic Acid; Central Nervous System; Evoked Potentials; Glutamates; Male; N-Methylaspartate; Oxadiazoles; Pyridines; Pyrrolidinones; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface	1983
Effects of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones. The Journal of physiology, 1983, Volume: 339 Topics: 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Female; Glutamates; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate	1983
In vivo release of [3H]-purines by quinolinic acid and related compounds. British journal of pharmacology, 1983, Volume: 80, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium	1983
Excitotoxic action of NMDA agonists on nigrostriatal dopaminergic neurons: modulation by inhibition of nitric oxide synthesis. Brain research, 1995, Apr-03, Volume: 676, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Corpus Striatum; Dose-Response Relationship, Drug; Immunohistochemistry; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra	1995
Differential stimulation of somatostatin but not neuropeptide Y gene expression by quinolinic acid in cultured cortical neurons. Journal of neurochemistry, 1995, Volume: 65, Issue:3 Topics: Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Fetus; Gene Expression; Hypothalamus; N-Methylaspartate; Neurons; Neuropeptide Y; Protein Kinase C; Quinolinic Acid; Rats; RNA, Messenger; Signal Transduction; Somatostatin	1995
Comparison of double fluorescence staining and LDH-test for monitoring cell viability in vitro. Neuroreport, 1993, Nov-18, Volume: 5, Issue:2 Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cytological Techniques; Fluoresceins; Fluorescent Dyes; Glutamates; Glutamic Acid; Hydrolysis; Kainic Acid; L-Lactate Dehydrogenase; Microscopy, Fluorescence; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotoxins; Propidium; Quinolinic Acid; Rats; Rats, Wistar	1993
[The effect of NMDA and quinolinic acid on cortical neurons of the rat brain]. Doklady Akademii nauk, 1993, Volume: 330, Issue:5 Topics: Animals; Cerebral Cortex; Membrane Potentials; N-Methylaspartate; Neurons; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate	1993
Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors? Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-06, Volume: 93, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Cyclopentanes; GABA Agonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microscopy, Video; Motor Activity; N-Methylaspartate; Neostriatum; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reference Values	1996
In vivo electrochemical studies of the dynamic effects of locally applied excitatory amino acids in the striatum of the anesthetized rat. Experimental neurology, 1996, Volume: 138, Issue:1 Topics: Adolescent; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Humans; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Potassium; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley	1996
The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochemistry international, 1996, Volume: 28, Issue:4 Topics: Animals; Cerebral Cortex; Female; Glutamic Acid; Glycine; Kainic Acid; Macromolecular Substances; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Oocytes; Polymerase Chain Reaction; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Messenger; Xenopus laevis	1996
Metabotropic glutamate receptor activation selectively limits excitotoxic damage in the intact neostriatum. Brain research, 1996, Jul-08, Volume: 726, Issue:1-2 Topics: Analysis of Variance; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neostriatum; Neuroprotective Agents; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1996
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996
Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation. Neuroscience, 1996, Volume: 74, Issue:4 Topics: Animals; bcl-2-Associated X Protein; Cell Death; Cerebral Cortex; DNA Fragmentation; DNA Nucleotidylexotransferase; GADD45 Proteins; Genes, p53; Immunohistochemistry; In Situ Hybridization; Injections; Intracellular Signaling Peptides and Proteins; Male; N-Methylaspartate; Neostriatum; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinolinic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Protein p53	1996
Neuronal cytotoxicity of inositol hexakisphosphate (phytate) in the rat hippocampus. Brain research, 1996, Nov-25, Volume: 741, Issue:1-2 Topics: Animals; Binding Sites; Cell Death; Cell Survival; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Agonists; Hippocampus; Male; N-Methylaspartate; Neurons; Phytic Acid; Quinolinic Acid; Rats; Rats, Wistar	1996
Discriminable excitotoxic effects of ibotenic acid, AMPA, NMDA and quinolinic acid in the rat laterodorsal tegmental nucleus. Brain research, 1997, Apr-25, Volume: 755, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics; Animals; Drug Evaluation, Preclinical; Ethanol; Excitatory Amino Acid Agonists; Ibotenic Acid; Locus Coeruleus; Male; N-Methylaspartate; Neurotoxins; Pentobarbital; Pons; Quinolinic Acid; Raphe Nuclei; Rats; Tegmentum Mesencephali	1997
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid. Neuroscience, 1997, Volume: 78, Issue:4 Topics: Alanine; Animals; Corpus Striatum; Dopamine; Drug Combinations; Injections, Intraventricular; Kynurenic Acid; Kynurenine; Male; N-Methylaspartate; Neurons; Neurotoxins; Niacin; Probenecid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase	1997
Neuroprotective effect of dapsone against quinolinate- and kainate-induced striatal neurotoxicities in rats. Pharmacology & toxicology, 1997, Volume: 81, Issue:6 Topics: Animals; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dapsone; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Quinolinic Acid; Rats; Rats, Wistar	1997
Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis. Neuroscience letters, 1998, Jan-30, Volume: 241, Issue:2-3 Topics: Animals; Apoptosis; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Logistic Models; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Quinolinic Acid; Rats; Rats, Sprague-Dawley	1998
Anticonvulsant activity of melatonin against seizures induced by quinolinate, kainate, glutamate, NMDA, and pentylenetetrazole in mice. Journal of pineal research, 1998, Volume: 24, Issue:4 Topics: Animals; Anticonvulsants; Brain; Convulsants; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Injections, Intraperitoneal; Injections, Intraventricular; Kainic Acid; Male; Melatonin; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Quinolinic Acid; Seizures	1998
Quinolinic acid and sigma receptor ligand: effect on pyramidal neurons of the CA1 sector of dorsal hippocampus following peripheral administration in rats. Folia neuropathologica, 1998, Volume: 36, Issue:2 Topics: Analgesics, Opioid; Animals; Calcium Channels; Hippocampus; Ligands; Male; N-Methylaspartate; Pentazocine; Pyramidal Cells; Quinolinic Acid; Rats; Rats, Wistar; Receptors, sigma	1998
Effects of mitochondria and o-methoxybenzoylalanine on 3-hydroxyanthranilic acid dioxygenase activity and quinolinic acid synthesis. Journal of neurochemistry, 1999, Volume: 72, Issue:3 Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Alanine; Animals; Brain; Dioxygenases; Enzyme Inhibitors; Hydrolases; In Vitro Techniques; Kynurenine; Liver; Mice; Mitochondria; Mitochondria, Liver; N-Methylaspartate; Oxygenases; Quinolinic Acid	1999
(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Animals; Anticonvulsants; Brain; Cell Line; Cell Membrane; Colforsin; Corpus Striatum; Cyclic AMP; Electroshock; Glutamic Acid; Glycine; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Protein Isoforms; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recombinant Proteins; Second Messenger Systems; Seizures; Structure-Activity Relationship	1999
Anticonvulsant properties of linalool in glutamate-related seizure models. Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:2 Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Glutamic Acid; Kindling, Neurologic; Male; Monoterpenes; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Seizures; Terpenes	1999
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity. Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-20, Volume: 96, Issue:15 Topics: Animals; Biomarkers; Brain; Cell Count; Cell Survival; Corpus Striatum; Exons; Humans; Huntington Disease; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate	1999
Quinolinic acid and GABA-B receptor ligand: effect on pyramidal neurons of the CA1 sector of rat's dorsal hippocampus following peripheral administration. Folia neuropathologica, 1999, Volume: 37, Issue:2 Topics: Animals; Baclofen; Drug Administration Routes; GABA Agonists; Hippocampus; Ligands; Male; N-Methylaspartate; Neurons; Pyramidal Cells; Quinolinic Acid; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate	1999
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. Experimental neurology, 1999, Volume: 159, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1999
3-Hydroxykynurenine potentiates quinolinate but not NMDA toxicity in the rat striatum. The European journal of neuroscience, 1999, Volume: 11, Issue:11 Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Benzenesulfonates; Corpus Striatum; Drug Synergism; Electron Transport Complex IV; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Kynurenine; Male; Motor Activity; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase	1999
Neuroprotective potency of kynurenic acid against excitotoxicity. Neuroreport, 2000, Apr-27, Volume: 11, Issue:6 Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Kynurenic Acid; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Quinolinic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	2000
Interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice. European journal of pharmacology, 2000, Jun-23, Volume: 398, Issue:3 Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar	2000
N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition. Journal of neurochemistry, 2001, Volume: 76, Issue:1 Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; HIV Envelope Protein gp120; Hydrogen-Ion Concentration; Male; N-Methylaspartate; Norepinephrine; Piperidines; Protein Kinase C; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptosomes; Zinc	2001
The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity. Experimental neurology, 2001, Volume: 167, Issue:1 Topics: Animals; Cerebral Decortication; Corpus Striatum; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	2001
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus. Physiological research, 2002, Volume: 51, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Molsidomine; N-Methylaspartate; Nerve Degeneration; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Wistar; Tritium	2002
Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions. Experimental neurology, 2002, Volume: 178, Issue:2 Topics: Animals; Astrocytes; Cell Count; Cell Death; Cell Differentiation; Excitatory Amino Acid Agonists; Genotype; Hippocampus; Ibotenic Acid; Immunohistochemistry; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; N-Methylaspartate; Neurons; Quinolinic Acid; Species Specificity; Staining and Labeling	2002
Excitotoxic degeneration of hypothalamic orexin neurons in slice culture. Neurobiology of disease, 2004, Volume: 15, Issue:1 Topics: Animals; Carrier Proteins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hypothalamic Hormones; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Melanins; N-Methylaspartate; Narcolepsy; Nerve Degeneration; Neurons; Neuropeptides; Neurotoxins; Orexin Receptors; Orexins; Pituitary Hormones; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolinic Acid; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide	2004
Characterization of striatal cultures with the effect of QUIN and NMDA. Neuroscience research, 2004, Volume: 49, Issue:1 Topics: Animals; Cell Death; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Immunohistochemistry; N-Methylaspartate; NADP; Neurons; Neuropeptide Y; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Somatostatin; Superoxide Dismutase; Time Factors	2004
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity. Journal of neurochemistry, 2004, Volume: 89, Issue:6 Topics: Animals; Body Weight; Calcium; Cells, Cultured; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Male; Maze Learning; Microdialysis; N-Methylaspartate; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate	2004
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum. Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1 Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Models, Biological; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Phenethylamines; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Triazines; Triazoles	2004
Accumulation of quinolinic acid with neuroinflammation: does it mean excitotoxicity? Advances in experimental medicine and biology, 2003, Volume: 527 Topics: Animals; Cerebral Cortex; Encephalitis; Lactic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Potassium; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate	2003
NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice. Epilepsia, 2004, Volume: 45, Issue:7 Topics: Animals; Apoptosis; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Humans; Male; Mice; Motor Activity; N-Methylaspartate; Neurons; Neurotoxicity Syndromes; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Seizures	2004
Divergent regulatory mechanisms governing BDNF mRNA expression in cerebral cortex and substantia nigra in response to striatal target ablation. Experimental neurology, 2005, Volume: 192, Issue:1 Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Corpus Striatum; Cyclopropanes; Denervation; Disease Models, Animal; Down-Regulation; Female; Glutamate Decarboxylase; Glycine; Huntington Disease; N-Methylaspartate; Neural Pathways; Neurons; Neurotoxins; Proto-Oncogene Proteins c-fos; Quinolinic Acid; Rats; Rats, Wistar; Receptor, trkB; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus; Tyrosine 3-Monooxygenase	2005
Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs. Brain research, 2006, Jan-19, Volume: 1069, Issue:1 Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hypercapnia; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Swine; Time Factors; Vasodilation	2006
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. Cell, 2006, Jun-16, Volume: 125, Issue:6 Topics: Active Transport, Cell Nucleus; Animals; Brain; Caspase 6; Caspases; Cell Nucleus; Humans; Huntingtin Protein; Huntington Disease; Hydrolysis; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Quinolinic Acid; Staurosporine	2006
Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity. Neuroscience, 2007, Aug-10, Volume: 148, Issue:1 Topics: Animals; Astrocytes; Cell Death; Corpus Striatum; Dopamine; Dopamine Agonists; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Humans; Kynurenic Acid; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate	2007
Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus. Brain research, 2007, Dec-12, Volume: 1184 Topics: Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hippocampus; Lipid Peroxidation; Male; Mice; N-Methylaspartate; Quinolinic Acid; Seizures	2007
Neurotoxic lesions of the medial prefrontal cortex or medial striatum impair multiple-location place learning in the water task: evidence for neural structures with complementary roles in behavioural flexibility. Experimental brain research, 2008, Volume: 187, Issue:3 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Corpus Striatum; Learning Disabilities; Maze Learning; N-Methylaspartate; Neurotoxins; Prefrontal Cortex; Quinolinic Acid; Rats; Rats, Long-Evans; Reaction Time; Reversal Learning; Spatial Behavior	2008
Somatostatin in medium-sized aspiny interneurons of striatum is responsible for their preservation in quinolinic acid and N-methyl-D-asparate-induced neurotoxicity. Journal of molecular neuroscience : MN, 2008, Volume: 35, Issue:3 Topics: Animals; Antibodies; Cell Survival; Cells, Cultured; Cytoprotection; Excitatory Amino Acid Antagonists; Interneurons; N-Methylaspartate; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; Neurotoxins; Oligonucleotides, Antisense; Pertussis Toxin; Quinolinic Acid; Rats; Receptors, Somatostatin; Somatostatin	2008
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-18, Volume: 29, Issue:7 Topics: Animals; Brain; Brain Ischemia; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Disease Progression; Genetic Predisposition to Disease; Huntington Disease; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Phenotype; Quinolinic Acid; Stress, Physiological; Synaptic Membranes; Synaptic Potentials; Synaptic Transmission	2009
Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors. Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:1 Topics: Adult; Amyotrophic Lateral Sclerosis; Animals; Brain; D-Aspartic Acid; Functional Laterality; Humans; Japan; Kynurenic Acid; Kynurenine; Motor Neurons; N-Methylaspartate; Quinolinic Acid; Riluzole; Signal Transduction; Tryptophan	2009
Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Oct-27, Volume: 30, Issue:43 Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Corpus Striatum; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Huntingtin Protein; Male; Mice; Mutation; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Quinolinic Acid; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques	2010
NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways. Behavioural brain research, 2011, May-16, Volume: 219, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Psychological; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Injections, Intraventricular; Isoquinolines; Male; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Seizures; Signal Transduction; Sulfonamides; Wortmannin	2011
Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function. ASN neuro, 2011, Jun-07, Volume: 3, Issue:3 Topics: Aging; Animals; Corpus Striatum; Disease Models, Animal; Electron Transport Chain Complex Proteins; Electron Transport Complex II; Electrophysiology; Huntingtin Protein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Prosencephalon; Quinolinic Acid	2011
NMDA preconditioning attenuates cortical and hippocampal seizures induced by intracerebroventricular quinolinic acid infusion. Neurotoxicity research, 2013, Volume: 24, Issue:1 Topics: Animals; Brain Waves; Cerebral Cortex; Hippocampus; Infusions, Intraventricular; Male; Mice; N-Methylaspartate; Neuroprotective Agents; Quinolinic Acid; Seizures	2013
N-methyl-D-aspartate preconditioning prevents quinolinic acid-induced deregulation of glutamate and calcium homeostasis in mice hippocampus. Neurotoxicity research, 2015, Volume: 27, Issue:2 Topics: Animals; Calcium; D-Aspartic Acid; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Homeostasis; Male; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinolinic Acid; Seizures	2015
Kynurenic Acid Prevents Cytoskeletal Disorganization Induced by Quinolinic Acid in Mixed Cultures of Rat Striatum. Molecular neurobiology, 2018, Volume: 55, Issue:6 Topics: Animals; Antioxidants; Astrocytes; Cell Communication; Cells, Cultured; Corpus Striatum; Cytoskeleton; Dizocilpine Maleate; Gap Junctions; Kynurenic Acid; Microglia; Models, Biological; N-Methylaspartate; Neurons; Oxidative Stress; Quinolinic Acid; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha	2018