quinolinic acid has been researched along with 3-hydroxyanthranilic acid in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (33.33) | 18.7374 |
| 1990's | 19 (31.67) | 18.2507 |
| 2000's | 9 (15.00) | 29.6817 |
| 2010's | 7 (11.67) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abagyan, R; Beck, L; Broide, DH; Elliott, GI; Gong, X; Hayashi, T; Jang, A; Kufareva, I; Lee, J; Mo, JH; Raz, E; Rossetto, C | 1 |
| Carpenter, BK; Schwarcz, R; Todd, WP; Walsh, JL | 2 |
| Gramsbergen, JB; Schwarcz, R; Speciale, C; Vezzani, A | 1 |
| Beninger, RJ; Bialik, M; Boegman, RJ; Jhamandas, K | 1 |
| Dykens, JA; Stern, A; Sullivan, SG | 2 |
| Okuno, E; Schwarcz, R; White, RJ | 1 |
| Schwarcz, R; Speciale, C; Ungerstedt, U | 1 |
| Foster, AC; Schwarcz, R; White, RJ | 1 |
| Chen, CY; Heyes, MP; Markey, SP; Naritsin, DB; Saito, K | 1 |
| Blight, AR; Cohen, TI; Heyes, MP; Saito, K | 1 |
| Heyes, MP; Markey, SP; Saito, K | 1 |
| Schwarcz, R; Ungerstedt, U; Walsh, JL; Wu, HQ | 1 |
| Heyes, MP; Major, EO; Markey, SP; Milstien, S; Saito, K; Vickers, JH | 1 |
| Heyes, MP; Markey, SP; Nowak, TS; Saito, K | 1 |
| Schwarcz, R; Speciale, C | 1 |
| Chen, CY; Crowley, JS; Heyes, MP; Markey, SP; Masana, M; Saito, K | 1 |
| Heyes, MP | 1 |
| Fornstedt-Wallin, B; Fredriksson, G; Luthman, J; Vänerman, E | 1 |
| Heyes, MP; Markey, SP; Noma, A; Saito, K; Seishima, M; Suyama, K | 1 |
| Brown, OR; Dang, Y; Xia, C | 1 |
| Chiarugi, A; Moroni, F | 1 |
| Handley, SL; Kariyawasam, SH | 1 |
| Fornstedt-Wallin, B; Fredriksson, G; Lundström, J; Luthman, J; Schwarcz, R | 1 |
| Guidetti, P; Schwarcz, R; Wu, HQ | 1 |
| Ceresoli-Borroni, G; Goodman, JH; Guidetti, P; Scharfman, HE; Schwarcz, R; Speciale, C; Varasi, M; Wu, HQ | 1 |
| Lehrmann, E; Molinari, A; Schwarcz, R; Speciale, C | 1 |
| Fukuwatari, T; Hayakawa, F; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| Bianchi, R; Fallarino, F; Fioretti, MC; Grohmann, U; Orabona, C; Puccetti, P; Spreca, A; Vacca, C | 1 |
| AURICCHIO, S; QUAGLIARIELLO, E; SORDINO, R | 1 |
| AURICCHIO, S; QUAGLIARIELLO, E | 1 |
| AURICCHIO, S; BARONE, B; QUAGLIARIELLO, E | 1 |
| AURICCHIO, S; QUAGLIARIELLO, E; RICCIO, R | 1 |
| AURICCHIO, S; QUAGLIARIELLO, E; RINALDI, E; VIOLANTE, A | 3 |
| AURICCHIO, S; QUAGLIARIELLO, E; RINALDI, E | 2 |
| AURICCHIO, S; COZZOLINO, D; QUAGLIARIELLO, E; SORDINO, R | 1 |
| MOLINE, SW; SCHWEIGERT, BS; WALKER, HC | 1 |
| BOKMAN, AH; SCHWEIGERT, BS | 1 |
| HENDERSON, LM; HIRSCH, HM | 1 |
| HENDERSON, LM; RAMASARMA, GB | 1 |
| BONNER, DM; YANOFSKY, C | 1 |
| Blight, AR; Heyes, MP; Yates, JR | 1 |
| Fukuwatari, T; Shibata, K | 1 |
| Dilović, I; Gliubich, F; Malpeli, G; Matković-Calogović, D; Zanotti, G | 1 |
| Du Preez, JL; Harvey, BH; Möller, M | 1 |
| Fukuwatari, T; Kondo, R; Sano, M; Shibata, K | 1 |
| Davis, I; Liu, A; Shamsi, SA; Wang, X | 1 |
| Fukuwatari, T; Funakoshi, H; Kadota, E; Kanai, M; Nakamura, T; Sano, M; Shibata, K; Terakata, M | 1 |
| Blight, AR; Gay, EA; Heyes, MP; Yates, JR | 1 |
| Advani, R; Giil, LM; Midttun, Ø; Refsum, H; Smith, AD; Ueland, PM; Ulvik, A | 1 |
| Shibata, K | 1 |
| Allers, KA; Harkin, A; McLoughlin, DM; Ryan, KM | 1 |
| Bugiani, M; Dijkhuis, A; Duitman, JW; Geeraerts, Z; Guo, L; Lutter, R; Nossent, EJ; Roos, E; Schurink, B; van der Valk, P; van Vught, L; Vaz, FM; Vlaar, AP; Yeh, SR | 1 |
| Altomare, A; Mercolini, L; Mondanelli, G; Protti, M; Regazzoni, L; Sanz, I; Valsecchi, V; Volpi, C | 1 |
| Asakawa, T; Chen, W; Jia, X; Qin, W; Shi, Y | 1 |
| Antony, J; Ardern-Holmes, S; Bandodkar, S; Dale, RC; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Innes, EA; Jones, HF; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pires, AS; Tantsis, E; Troedson, C; Tsang, E; Webster, R; Wienholt, L; Yan, J | 1 |
3 review(s) available for quinolinic acid and 3-hydroxyanthranilic acid
| Article | Year |
|---|---|
The kynurenine pathway and neurologic disease. Therapeutic strategies.
Topics: 3-Hydroxyanthranilic Acid; Animals; Gerbillinae; Guinea Pigs; Humans; Kynurenine; Macrophage Activation; Mice; Nervous System Diseases; Neurotoxins; Primates; Quinolinic Acid; Rats; Spinal Cord; Spinal Cord Injuries | 1996 |
Organ Co-Relationship in Tryptophan Metabolism and Factors That Govern the Biosynthesis of Nicotinamide from Tryptophan.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Diet; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Liver; Niacinamide; Nutritional Status; Pentosyltransferases; Quinolinic Acid; Tryptophan; Vitamin B Deficiency; Xanthurenates | 2018 |
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information.
Topics: 3-Hydroxyanthranilic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Levodopa; Parkinson Disease; Quinolinic Acid; Tryptophan | 2022 |
57 other study(ies) available for quinolinic acid and 3-hydroxyanthranilic acid
| Article | Year |
|---|---|
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis.
Topics: 3-Hydroxyanthranilic Acid; Animals; Apoptosis; Asthma; Cell Line; Disease Models, Animal; Enzyme Activation; Humans; Lymphocyte Activation; Mice; Models, Molecular; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Receptors, Antigen, T-Cell; T-Lymphocytes | 2007 |
4-halo-3-hydroxyanthranilic acids: potent competitive inhibitors of 3-hydroxy-anthranilic acid oxygenase in vitro.
Topics: 3-Hydroxyanthranilic Acid; Animals; Kinetics; Liver; Models, Chemical; Oxidoreductases; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
4-Halo-3-hydroxyanthranilates are potent inhibitors of 3-hydroxyanthranilate oxygenase in the rat brain in vitro and in vivo.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Dialysis; Dioxygenases; Hippocampus; Male; Oxygenases; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Production of quinolinic acid and kynurenic acid by human glioma.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Astrocytoma; Brain Neoplasms; Dioxygenases; Humans; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Neoplasm Proteins; Oxygenases; Quinolinic Acid; Quinolinic Acids | 1991 |
Quinolinate-induced cortical cholinergic damage: modulation by tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Acetylcholine; Animals; Brain; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Male; Neurotoxins; Parietal Lobe; Picolinic Acids; Potassium; Quinolines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
Glucose metabolism and hemoglobin reactivity in human red blood cells exposed to the tryptophan metabolites 3-hydroxyanthranilate, quinolinate and picolinate.
Topics: 3-Hydroxyanthranilic Acid; Erythrocytes; Formates; Glucose; Glycolysis; Hemoglobins; Humans; ortho-Aminobenzoates; Pentetic Acid; Pentose Phosphate Pathway; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Superoxide Dismutase | 1989 |
Basal ganglia lesions in the rat: effects on quinolinic acid metabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Corpus Striatum; Hydroxydopamines; Ibotenic Acid; Male; Neuroglia; Neurotoxins; Oxidopamine; Pentosyltransferases; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Production of extracellular quinolinic acid in the striatum studied by microdialysis in unanesthetized rats.
Topics: 3-Hydroxyanthranilic Acid; Animals; Corpus Striatum; Extracellular Space; Ibotenic Acid; Kynurenic Acid; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1989 |
Synthesis of quinolinic acid by 3-hydroxyanthranilic acid oxygenase in rat brain tissue in vitro.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Brain; Dioxygenases; In Vitro Techniques; Male; Methods; Oxygenases; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1986 |
Oxidative reactivity of the tryptophan metabolites 3-hydroxyanthranilate, cinnabarinate, quinolinate and picolinate.
Topics: 3-Hydroxyanthranilic Acid; Catalase; Hydrogen-Ion Concentration; Kinetics; ortho-Aminobenzoates; Oxazines; Oxidation-Reduction; Oxygen Consumption; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Superoxide Dismutase; Tryptophan | 1987 |
Metabolism of L-tryptophan to kynurenate and quinolinate in the central nervous system: effects of 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cell Line; Central Nervous System; Gas Chromatography-Mass Spectrometry; Humans; Kynurenic Acid; Kynurenine; Lyases; Macaca mulatta; Quinolinic Acid; Transaminases; Tryptophan | 1995 |
Quinolinic acid accumulation and functional deficits following experimental spinal cord injury.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Dioxygenases; Evoked Potentials, Somatosensory; Female; Guinea Pigs; Macrophage Activation; Myelitis; Oxygenases; Quinolinic Acid; Reflex, Abnormal; Silicon Dioxide; Spinal Cord Compression; Spinal Cord Injuries | 1995 |
6-Chloro-D,L-tryptophan, 4-chloro-3-hydroxyanthranilate and dexamethasone attenuate quinolinic acid accumulation in brain and blood following systemic immune activation.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Dexamethasone; Immune System; Kynurenine; Lung; Male; Mice; Mice, Inbred C57BL; Pokeweed Mitogens; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1994 |
4-Chloro-3-hydroxyanthranilate inhibits quinolinate production in the rat hippocampus in vivo.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Dioxygenases; Dose-Response Relationship, Drug; Extracellular Space; Hippocampus; Male; Microdialysis; Oxygenases; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 1994 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Macaca mulatta; Myelitis; Neopterin; Poliomyelitis; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1993 |
Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Female; Gerbillinae; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ischemic Attack, Transient; Kynurenine; Macrophages; Pokeweed Mitogens; Quinolinic Acid; Time Factors; Tryptophan; Tryptophan Oxygenase | 1993 |
On the production and disposition of quinolinic acid in rat brain and liver slices.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Ibotenic Acid; In Vitro Techniques; Liver; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 1993 |
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Carbolines; Cell Line; Harmine; Humans; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Macrophages; Quinolinic Acid; Rats; Tryptophan; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Regulation of quinolinic acid in the normal rat brain by kynurenine pathway precursors.
Topics: 3-Hydroxyanthranilic Acid; Analysis of Variance; Animals; Cerebral Ventricles; Hippocampus; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Kynurenine; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tryptophan | 1996 |
4-chloro-3-hydroxyanthranilate attenuate quinolinic acid accumulation in brain following transient cerebral ischemia in the gerbil.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Dexamethasone; Female; Gerbillinae; Ischemic Attack, Transient; Kynurenine; Organ Specificity; Quinolinic Acid; Reference Values; Tryptophan Oxygenase | 1996 |
Effects of oxygen on 3-hydroxyanthranilate oxidase of the kynurenine pathway.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Enzyme Activation; Enzyme Inhibitors; Humans; Iron; Kinetics; Kynurenine; Liver; Oxidoreductases; Oxygen; Quinolinic Acid; Rats | 1998 |
Effects of mitochondria and o-methoxybenzoylalanine on 3-hydroxyanthranilic acid dioxygenase activity and quinolinic acid synthesis.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Alanine; Animals; Brain; Dioxygenases; Enzyme Inhibitors; Hydrolases; In Vitro Techniques; Kynurenine; Liver; Mice; Mitochondria; Mitochondria, Liver; N-Methylaspartate; Oxygenases; Quinolinic Acid | 1999 |
Quinolinic acid inhibits DOI-induced head shakes in mice.
Topics: 3-Hydroxyanthranilic Acid; Amphetamines; Animals; Dose-Response Relationship, Drug; Head Movements; Injections, Intraventricular; Injections, Subcutaneous; Kynurenine; Male; Mice; Quinolinic Acid; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reflex; Serotonin Receptor Agonists | 1999 |
3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Brain; Dioxygenases; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Kynurenic Acid; Male; Oxygenases; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 1999 |
In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biotransformation; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Kynurenic Acid; Kynurenine; Male; Malonates; Neurons; Neuroprotective Agents; Prodrugs; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glycine | 2000 |
Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo.
Topics: 3-Hydroxyanthranilic Acid; Animals; Blood-Brain Barrier; Butyrates; Enzyme Inhibitors; Hippocampus; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Neuroprotective Agents; Neurotoxins; Pyramidal Cells; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 2000 |
Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum.
Topics: 3-Hydroxyanthranilic Acid; Animals; Corpus Striatum; Drug Combinations; Immunohistochemistry; Macrophages; Male; Microglia; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reference Values | 2001 |
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency; Tryptophan; Xanthurenates | 2001 |
T cell apoptosis by tryptophan catabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Apoptosis; Autoimmune Diseases; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; fas Receptor; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Mitochondria; Quinolinic Acid; Self Tolerance; T-Lymphocytes; Th1 Cells; Thymus Gland; Tryptophan | 2002 |
[Effect of menadione on the conversion of 3-hydroxyanthranilic acid to quinolinic acid in the rat liver].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Antifibrinolytic Agents; Carcinogens; Liver; Naphthoquinones; Pyridines; Quinolinic Acid; Vitamin K; Vitamin K 3 | 1956 |
[Action of synkavit on conversion of 3-hydroxyanthranilic acid to quinolinic acid].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Antifibrinolytic Agents; Carcinogens; Pyridines; Quinolinic Acid; Vitamin K | 1956 |
[Action of synkavit on conversion of 3-hydroxyanthranilic acid to quinolinic acid].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Antifibrinolytic Agents; Carcinogens; Pyridines; Quinolinic Acid; Vitamin K | 1956 |
[Inhibition by phenylhydrazine of the 3-hydroxyanthranilic acid quinolinic acid reaction].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Carcinogens; Phenylhydrazines; Pyridines; Quinolinic Acid | 1956 |
[Conversion of 3-hydroxyanthranilic acid to quinolinic acid in the presence of liver tissue in rats in Oberling's myeloma in leukemic phase].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Animals; Leukemia, Experimental; Liver; Multiple Myeloma; Plasma Cells; Pyridines; Quinolinic Acid; Rats | 1957 |
Conversion of 3-hydroxyanthranilic acid to quinolinic acid in presence of rat liver treated with 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; 3-Hydroxyanthranilic Acid; Aminobenzoates; Carcinogens; Fluorenes; Liver; Pyridines; Quinolinic Acid | 1958 |
On the conversion of 3-hydroxyanthranilic acid to quinolinic acid in presence of hepatic tissue of rats affected by Oberling's myeloma in the leukemic phase.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Animals; Liver; Multiple Myeloma; Plasma Cells; Pyridines; Quinolinic Acid; Rats | 1958 |
On the enzymic conversion of 3-hydroxyanthranilic acid into quinolinic acid.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Biochemical Phenomena; Liver; Pyridines; Quinolinic Acid | 1958 |
[Metabolism of 3-hydroxyanthranilic acid, quinolinic acid & nicotinic acid in Escherichia coli].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Biochemical Phenomena; Escherichia coli; Niacin; Nicotinic Acids; Pyridines; Quinolinic Acid | 1958 |
On the effect of DPN on the conversion of 3-hydroxyanthranilic acid to quinolinic acid in presence of hepatic tissue of rats affected by Oberling's myeloma in the leukemic phase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Coenzymes; Leukemia; Leukemia, Myeloid; Liver; Multiple Myeloma; NAD; Pyridines; Quinolinic Acid; Rats | 1958 |
3-Hydroxyanthranilic acid metabolism. VII. Mechanism of formation of quinolinic acid.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Pyrans; Quinolinic Acid | 1959 |
3-Hydroxyanthranilic acid metabolism. III. Molar conversion to quinolinic acid.
Topics: 3-Hydroxyanthranilic Acid; Molar; ortho-Aminobenzoates; Quinolinic Acid | 1950 |
Quinolinic acid metabolism; urinary excretion by the rat following tryptophan and 3-hydroxyanthranilic acid administration.
Topics: 3-Hydroxyanthranilic Acid; Animals; Body Fluids; Quinolines; Quinolinic Acid; Rats; Tryptophan; Urine | 1949 |
Quinolinic acid metabolism; formation from 3-hydroxyanthranilic acid by rat liver preparations.
Topics: 3-Hydroxyanthranilic Acid; Acids; Animals; Liver; Quinolines; Quinolinic Acid; Rats | 1949 |
Quinolinic acid accumulation in the conversion of 3-hydroxyanthranilic acid to niacin in Neurospora.
Topics: 3-Hydroxyanthranilic Acid; Fungi; Neurospora; Niacin; Quinolinic Acid | 1949 |
4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury.
Topics: 3-Hydroxyanthranilic Acid; Algorithms; Animals; Behavior, Animal; Blood-Brain Barrier; Female; Guinea Pigs; Kynurenic Acid; Myelin Sheath; Permeability; Proprioception; Quinolinic Acid; Reference Standards; Reflex, Monosynaptic; Spinal Cord Compression; Spinal Cord Injuries | 2006 |
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Feedback, Physiological; Female; Humans; Kynurenic Acid; Niacinamide; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates | 2007 |
Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cattle; Crystallization; Crystallography, X-Ray; Glutamic Acid; Histidine; Iron; Kidney; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinolinic Acid; Sequence Homology, Amino Acid | 2009 |
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan | 2012 |
Increased conversion of tryptophan to nicotinamide in rats by dietary valproate.
Topics: 3-Hydroxyanthranilic Acid; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food, Formulated; Liver; Male; Niacinamide; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Valproic Acid | 2013 |
Development of a CZE-ESI-MS assay with a sulfonated capillary for profiling picolinic acid and quinolinic acid formation in multienzyme system.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Buffers; Carboxy-Lyases; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Multienzyme Complexes; Picolinic Acids; Pressure; Quinolinic Acid; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2013 |
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Body Weight; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Niacin; Niacinamide; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2013 |
Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms.
Topics: 3-Hydroxyanthranilic Acid; Animals; Behavior, Animal; Disease Models, Animal; Evoked Potentials, Somatosensory; Female; Guinea Pigs; Methylprednisolone; Quinolinic Acid; Spinal Cord Injuries | 2014 |
Kynurenine Pathway Metabolites in Alzheimer's Disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Female; Humans; Kynurenine; Male; Middle Aged; Neuropsychological Tests; Quinolinic Acid; Signal Transduction; Statistics, Nonparametric; Tryptophan; Xanthurenates | 2017 |
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy.
Topics: 3-Hydroxyanthranilic Acid; Affect; Case-Control Studies; Electroconvulsive Therapy; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Tryptophan; Xanthurenates | 2020 |
Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Apoptosis; Autopsy; Brain; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung; Middle Aged; Myocardium; Prospective Studies; Quinolinic Acid; Severity of Illness Index; Tryptophan | 2022 |
Chromatographic measurement of 3-hydroxyanthranilate 3,4-dioxygenase activity reveals that edaravone can mitigate the formation of quinolinic acid through a direct enzyme inhibition.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Amyotrophic Lateral Sclerosis; Edaravone; Humans; Neurodegenerative Diseases; Quinolinic Acid | 2022 |
Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids.
Topics: 3-Hydroxyanthranilic Acid; Adrenal Cortex Hormones; Animals; Biomarkers; Chromatography, Liquid; Epilepsy; Kynurenic Acid; Kynurenine; Male; Quinolinic Acid; Spasm; Tandem Mass Spectrometry; Tryptophan | 2022 |