Page last updated: 2024-08-17

quinidine and yohimbine

quinidine has been researched along with yohimbine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Guengerich, FP; Stöckigt, J; Strobl, GR; von Kruedener, S; Wolff, T1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Flanagan, JU; Kemp, CA; Maréchal, JD; Paine, MJ; Roberts, GC; Sutcliffe, MJ; van Eldik, AJ; Wolf, CR1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Den Hertog, A; Van den Akker, J1
Coignet, JL; Vargaftig, B1
Insel, PA; Maisel, AS; Motulsky, HJ; Snavely, MD1

Other Studies

8 other study(ies) available for quinidine and yohimbine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Alkaloids; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Ethanolamines; Humans; Indoles; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinolines; Secologanin Tryptamine Alkaloids; Yohimbine

1993
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Validation of model of cytochrome P450 2D6: an in silico tool for predicting metabolism and inhibition.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Binding Sites; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Databases, Factual; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The action of procainamide and quinidine on the alpha 1-receptor-operated channels in smooth muscle cells of guinea-pig taenia caeci.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: Animals; Atropine; Calcium; Cecum; Cell Membrane Permeability; Epinephrine; Guinea Pigs; In Vitro Techniques; Ion Channels; Muscle, Smooth; Procainamide; Propranolol; Quinidine; Receptors, Adrenergic, alpha; Yohimbine

1987
A critical evaluation of three methods for the study of adrenergic beta-blocking and anti-arrhythmic agents.
    European journal of pharmacology, 1969, Volume: 6, Issue:1

    Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bronchi; Chloroform; Constriction; Dibenzylchlorethamine; Electrocardiography; Ethanolamines; Female; Guinea Pigs; Isoproterenol; Lidocaine; Male; Phentolamine; Procainamide; Propranolol; Quinidine; Reserpine; Serotonin; Sympatholytics; Ventricular Fibrillation; Yohimbine

1969
Quinidine is a competitive antagonist at alpha 1- and alpha 2-adrenergic receptors.
    Circulation research, 1984, Volume: 55, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Blood Platelets; Humans; In Vitro Techniques; Kidney; Lidocaine; Myocardium; Prazosin; Quinidine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1984