Page last updated: 2024-08-17

quinidine and warfarin

quinidine has been researched along with warfarin in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (46.51)	18.7374
1990's	8 (9.30)	18.2507
2000's	25 (29.07)	29.6817
2010's	11 (12.79)	24.3611
2020's	2 (2.33)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I	1
Jolivette, LJ; Ward, KW	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, CH; De Clercq, E; Feng, D; Ginex, T; Kang, D; Lee, KH; Liu, X; Luque, FJ; Murugan, NA; Pannecouque, C; Steitz, TA; Wang, Z; Wei, F; Wu, G; Yang, Y; Zhan, P; Zhang, H; Zhang, J; Zhao, T	1
Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C	1
Abadi, AH; Abdel-Halim, M; Engel, M; Fathalla, RK; Hammam, MA; Hartmann, RW; Hefnawy, A; Keeton, AB; Maher, A; Maxuitenko, Y; Piazza, GA; Racheed, NAS; Sigler, S	1
Koike, H; Nakayama, K; Oshima, T	1
Romankiewicz, JA	1
Belpaire, FM; Bogaert, MG; Mussche, MM	1
Jacobsen, S; Nilsen, OG; Storstein, L	1
Himberg, JJ; Julkunen, RJ	1
Haynes, JH; Kageler, WV	1
Hattori, N; Kobayashi, K; Matsushita, E; Morimoto, H; Tanaka, N	1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y	1
Holmes, J; Sapeika, N; Zwarenstein, H	2
Kellaway, GS; McCrae, E	1
Kovách, GB; Sándor, P	1
Borodkin, S; Yunker, MH	1
Sellers, E; Weser, JK	1
Keresztes-Nagy, S; Mais, RF; Oester, YT; Zaroslinski, JF	1
Smith, GH	1
Seiler, K	1
Anderson, WT; Cheitlin, MD; Golden, MS; Pinder, T	1
Tejani, N	1
Artinian, B; Reesal, M	1
DeSanctis, RW; Hutter, AM; Krauss, KR	1
Blount, AW; Miller, DS	1
Koch-Weser, J	1
Jones, FL	1
Gazzaniga, AB; Stewart, DR	1
Awalt, LF	1
Bailey, KR; Gallo, DG; Sheffner, AL	1
Eliot, RS; Ferlic, R; Lillehei, CW; Sellers, RD	1
Sarkany, I	1
Marcus, FI	1
Runge, M	1
Walan, A	1
Müller, FO; Steyn, JM	1
Sharp, AA	1
D'Arcy, PF	1
Friedman, C; Romem, M; Singer, L	1
Gornbein, JA; Middlekauff, HR; Stevenson, WG	1
Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC	1
Jähnchen, E; Möhrke, W; Trenk, D; Warth, L	1
Birkmeyer, JD; Disch, DL; Greenberg, ML; Holzberger, PT; Malenka, DJ	1
Gibaldi, M	1
Disch, DL; Greenberg, ML; Malenka, DJ	1
Jones, BC; Smith, DA; Tyman, CA	1
Gorski, JC; Hall, SD; Hamman, MA; Jones, DR; Wrighton, SA	1
Baillie, TA; Chen, Q; Ngui, JS; Shou, M; Stearns, RA; Tang, W; Wang, RW	1
Cai, H; Guengerich, FP; Hanna, IH; Nakamura, K; Nishimura, Y; Williams, KM	1
Beckurts, KT; Brachtendorf, L; Fuhr, U; Hölscher, AH; Jetter, A	1
Commandeur, JN; Funae, Y; Hiroi, T; ter Laak, AM; Venhorst, J; Vermeulen, NP	1
Axelsson, H; Floby, E; Granhall, C; Jaksch, Y; Sohlenius-Sternbeck, AK; Svedling, M	1
PREZIOSI, P	1
ARENA, JM	1
COWEN, DL	1
KNABE, J	1
Fouda, HG; Khojasteh-Bakht, SC; Prakash, C; Rossulek, MI	1
Baillie, TA; Booth-Genthe, C; Chen, Q; Evans, DC; Fenyk-Melody, JE; Rushmore, TH; Stearns, RA; Strauss, JR; Tan, E; Tang, W; Zhang, Z	1
Baillie, TA; Evans, DC; Li, Y; Ngui, JS; Shou, M; Stearns, RA; Tang, W; Zhang, Y; Zhang, Z	1
Flarakos, J; Morand, KL; Vouros, P	1
Gottesdiener, KM; Kari, PP; Marbury, T; Miller, JL; Mistry, GC; Rodrigues, AD; Simpson, RC; Wagner, JA; Winchell, GA	1
Fuhr, U; Kober, S; Mutschler, E; Spahn-Langguth, H; Zaigler, M	1
Hansen, SH; Jensen, H; Thomsen, AE; Østergaard, J	1
Ahmad, K; Ahmad, SS; Alam, Q; Alnamshan, MM; Alqosaibi, AI; Alshamrani, S; Bahnass, MM; Beg, MMA; Chaturvedi, N; Mashraqi, MM; Mishra, A; Rizvi, SMD; Shaikh, S	1

Reviews

10 review(s) available for quinidine and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Toxic hepatitis induced by cardiovascular agents]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:6 Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiovascular Agents; Chemical and Drug Induced Liver Injury; Diuretics; Humans; Male; Methyldopa; Procaine; Quinidine; Warfarin	1985
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats. Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5 Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin	1985
Drug interactions with coumarin anticoagulants. 2. The New England journal of medicine, 1971, Sep-02, Volume: 285, Issue:10 Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide	1971
[Therapy of arrhythmia during pregnancy]. Deutsche medizinische Wochenschrift (1946), 1984, Jun-15, Volume: 109, Issue:24 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biotransformation; Coumarins; Digoxin; Drug Synergism; Female; Fetal Growth Retardation; Fetus; Heparin; Humans; Infant, Newborn; Milk, Human; Pacemaker, Artificial; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Verapamil	1984
Antiarrhythmic prophylaxis vs warfarin anticoagulation to prevent thromboembolic events among patients with atrial fibrillation. A decision analysis. Archives of internal medicine, 1995, May-08, Volume: 155, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Atrial Fibrillation; Confounding Factors, Epidemiologic; Decision Support Techniques; Electric Countershock; Female; Humans; Male; Middle Aged; Quinidine; Risk; Thromboembolism; Treatment Outcome; Warfarin	1995
Managing chronic atrial fibrillation: a Markov decision analysis comparing warfarin, quinidine, and low-dose amiodarone. Annals of internal medicine, 1994, Mar-15, Volume: 120, Issue:6 Topics: Aged; Amiodarone; Atrial Fibrillation; Chronic Disease; Decision Support Techniques; Humans; Markov Chains; Quality of Life; Quinidine; Risk Factors; Warfarin	1994
Stereoselective and isozyme-selective drug interactions. Chirality, 1993, Volume: 5, Issue:6 Topics: Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Isoenzymes; Quinidine; Rifampin; Stereoisomerism; Warfarin	1993
Therapeutic strategies for atrial fibrillation. The value of decision analysis. Cardiology clinics, 1996, Volume: 14, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Chronic Disease; Decision Support Techniques; Electric Countershock; Humans; Markov Chains; Quinidine; Randomized Controlled Trials as Topic; Warfarin	1996
[CHEMISTRY OF CARDIAC DRUGS]. Medizinische Monatsschrift, 1964, Volume: 18 Topics: Alkaloids; Anti-Arrhythmia Agents; Cardiovascular Agents; Coumarins; Digitalis Glycosides; Dipyridamole; Humans; Nitrates; Nitrites; Phenols; Prenylamine; Procainamide; Quinidine; Rauwolfia; Vasodilator Agents	1964

Trials

2 trial(s) available for quinidine and warfarin

Article	Year
Determination of the interaction of 3S-hydroxy-10,11-dihydroquinidine on the pharmacokinetics and pharmacodynamics of warfarin. Arzneimittel-Forschung, 1993, Volume: 43, Issue:8 Topics: Adult; Anti-Arrhythmia Agents; Drug Interactions; Half-Life; Hemorrhage; Humans; Male; Prothrombin; Quinidine; Risk; Warfarin	1993
The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist. Journal of clinical pharmacology, 2005, Volume: 45, Issue:6 Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Area Under Curve; Carbon Radioisotopes; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fomepizole; Half-Life; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrazoles; Pyrimidinones; Quinidine; Receptors, Adrenergic, alpha-1; Sulfaphenazole; Theophylline	2005

Article

Year

Determination of the interaction of 3S-hydroxy-10,11-dihydroquinidine on the pharmacokinetics and pharmacodynamics of warfarin.

Arzneimittel-Forschung, 1993, Volume: 43, Issue:8

Topics: Adult; Anti-Arrhythmia Agents; Drug Interactions; Half-Life; Hemorrhage; Humans; Male; Prothrombin; Quinidine; Risk; Warfarin

1993

The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.

Journal of clinical pharmacology, 2005, Volume: 45, Issue:6

Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Area Under Curve; Carbon Radioisotopes; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fomepizole; Half-Life; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrazoles; Pyrimidinones; Quinidine; Receptors, Adrenergic, alpha-1; Sulfaphenazole; Theophylline

2005

Other Studies

74 other study(ies) available for quinidine and warfarin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors. Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4 Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship	2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Anti-HIV Agents; Binding Sites; Cell Line, Tumor; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Male; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Molecular Structure; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2019
Development of Robust 17( Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar	2019
From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity. Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8 Topics: Animals; Blood Proteins; Celecoxib; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Design; Female; Half-Life; Humans; Isoenzymes; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phosphodiesterase 5 Inhibitors; Protein Binding; Pyrazoles; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship	2021
Antiarrhythmic activity of dextro- and levo-isomers of 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrocholoride (bucumolol), a beta-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs. Japanese journal of pharmacology, 1979, Volume: 29, Issue:6 Topics: Aconitine; Aconitum; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmias, Cardiac; Coumarins; Dogs; Female; Guinea Pigs; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Ouabain; Propanolamines; Propranolol; Quinidine; Refractory Period, Electrophysiological; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship	1979
Effects of antacids on gastrointestinal absorption of drugs. Primary care, 1976, Volume: 3, Issue:3 Topics: Animals; Antacids; Aspirin; Chlordiazepoxide; Chlorpromazine; Dicumarol; Digitoxin; Digoxin; Ephedrine; Guinea Pigs; Humans; Intestinal Absorption; Iron; Isoniazid; Levodopa; Naproxen; Pentobarbital; Pharmaceutical Preparations; Quinidine; Quinine; Rats; Sulfadiazine; Tetracyclines; Warfarin	1976
Influence of acute renal failure on the protein binding of drugs in animals and in man. European journal of clinical pharmacology, 1977, Volume: 11, Issue:1 Topics: Acute Kidney Injury; Animals; Blood Proteins; Cats; Digitoxin; Dogs; Female; Guinea Pigs; Humans; Male; Papaverine; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Rabbits; Rats; Species Specificity; Time Factors; Uranyl Nitrate; Urea; Warfarin	1977
Effect of heparin and fatty acids on the binding of quinidine and warfarin in plasma. Biochemical pharmacology, 1977, Feb-01, Volume: 26, Issue:3 Topics: Adult; Blood Proteins; Fatty Acids, Nonesterified; Heparin; Humans; In Vitro Techniques; Lipoproteins; Male; Palmitic Acids; Protein Binding; Quinidine; Serum Albumin; Time Factors; Warfarin	1977
Dry polyacrylamide batch method for studying drug protein binding. Arzneimittel-Forschung, 1976, Volume: 26, Issue:4 Topics: Chromatography, Gel; Humans; Phenylbutazone; Protein Binding; Quinidine; Serum Albumin; Sulfadiazine; Sulfisoxazole; Warfarin	1976
Thyrocardiotoxic embolic syndrome. Southern medical journal, 1989, Volume: 82, Issue:10 Topics: Adult; Atrial Fibrillation; Embolism; Female; Femoral Artery; Humans; Quinidine; Syndrome; Thyrotoxicosis; Warfarin	1989
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1 Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin	1974
Intensive monitoring for adverse drug effects in patients discharged from acute medical wards. The New Zealand medical journal, 1973, Dec-26, Volume: 78, Issue:505 Topics: Adolescent; Adult; Age Factors; Aged; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Edema; Ethnicity; Female; Glyburide; Glycyrrhiza; Hematologic Diseases; Hospitalization; Humans; Male; Middle Aged; New Zealand; Outpatient Clinics, Hospital; Phenobarbital; Plants, Medicinal; Purpura, Thrombocytopenic; Quinidine; Sex Factors; Succinates; Triterpenes; Warfarin	1973
Comparative studies on the influence of different anti-arrhythmic drugs on the alpha- and beta-receptors in cat blood pressure test. Arzneimittel-Forschung, 1968, Volume: 18, Issue:10 Topics: Animals; Anti-Arrhythmia Agents; Arteries; Blood Pressure; Cats; Coumarins; Female; Heart Rate; Histamine H1 Antagonists; Imidazoles; Isoproterenol; Male; Norepinephrine; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Sensory Receptor Cells; Sparteine; Stimulation, Chemical	1968
Interaction of amine drugs with a polycarboxylic acid ion-exchange resin. Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:4 Topics: Acids; Adsorption; Alkaloids; Amines; Chromatography, Ion Exchange; Coumarins; Drug Incompatibility; Ephedrine; Glycolates; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Ion Exchange Resins; Mathematics; Methamphetamine; Morphinans; Neostigmine; Phenylpropanolamine; Polymers; Pyridines; Quinidine; Sodium; Spectrophotometry; Temperature; Thiamine; Time Factors; Ultraviolet Rays	1970
Interpretation of protein-drug interaction through fraction bound and relative contribution of secondary sites. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:9 Topics: Binding Sites; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gel; Computers; Humans; In Vitro Techniques; Kinetics; Ligands; Mathematics; Models, Biological; Pharmaceutical Preparations; Protein Binding; Quinidine; Salicylates; Serum Albumin; Spectrophotometry; Warfarin	1974
Case studies of a clinical pharmacist. American journal of hospital pharmacy, 1972, Volume: 29, Issue:11 Topics: Aged; Alcoholism; Allopurinol; Arrhythmias, Cardiac; Chloral Hydrate; Colchicine; Digoxin; Drug Synergism; Gastrointestinal Hemorrhage; Gout; Hospitals, Teaching; Humans; Liver Diseases; Male; Middle Aged; Nitroglycerin; Patient Care Team; Pharmacists; Pharmacy Service, Hospital; Quinidine; Warfarin; Washington	1972
[Defect in oral anticoagulation. Etiology and explanation]. Schweizerische medizinische Wochenschrift, 1972, Oct-07, Volume: 102, Issue:40 Topics: Anticoagulants; Blood Coagulation Disorders; Chloramphenicol; Coumarins; Drug Interactions; Glucagon; Humans; Models, Biological; Neomycin; Phenylbutazone; Protein Binding; Quinidine; Vitamin K	1972
Fatal pulmonary hemorrhage complicating use of a flow-directed balloon-tipped catheter in a patient receiving anticoagulant therapy. The American journal of cardiology, 1973, Volume: 32, Issue:6 Topics: Adult; Anticoagulants; Autopsy; Cardiac Catheterization; Digoxin; Female; Hematoma; Hemorrhage; Humans; Lung Diseases; Pulmonary Artery; Quinidine; Rupture; Warfarin	1973
Anticoagulant therapy with cardiac valve prosthesis during pregnancy. Obstetrics and gynecology, 1973, Volume: 42, Issue:5 Topics: Adult; Anticoagulants; Digoxin; Dipyridamole; Female; Heart Valve Prosthesis; Heparin; Humans; Mitral Valve; Pregnancy; Pregnancy Complications, Cardiovascular; Quinidine; Rheumatic Heart Disease; Warfarin	1973
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2 Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts	1973
Procainamide-induced SLE and lymphoreticular disorders. Canadian Medical Association journal, 1974, Feb-02, Volume: 110, Issue:3 Topics: Aortic Diseases; Autopsy; Blindness; Bone Marrow; Digoxin; Drug Therapy, Combination; Heart Diseases; Heparin; Humans; Immunologic Deficiency Syndromes; Kidney; Lupus Erythematosus, Systemic; Lymph Nodes; Lymphoma; Male; Middle Aged; Procainamide; Quinidine; Retinal Artery; Spleen; Thromboembolism; Warfarin	1974
Acute coronary insufficiency. Course and follow-up. Circulation, 1972, Volume: 45, Issue:1 Suppl Topics: Adult; Aged; Angina Pectoris; Aspartate Aminotransferases; Coronary Disease; Creatine Kinase; Electrocardiography; Female; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Myocardial Infarction; Nitrates; Procainamide; Propranolol; Quinidine; Warfarin	1972
Quinidine-induced recurrent ventricular fibrillation: (quinidine syncope) treated with transvenous pacemaker. Southern medical journal, 1971, Volume: 64, Issue:5 Topics: Adult; Atrial Fibrillation; Atropine; Blood Cell Count; Chlorpromazine; Coumarins; Creatine Kinase; Digitalis Glycosides; Diuretics; Electric Countershock; Electrocardiography; Female; Heart Valve Prosthesis; Humans; L-Lactate Dehydrogenase; Lactates; Lidocaine; Mitral Valve Stenosis; Pacemaker, Artificial; Paranoid Disorders; Pneumonia; Potassium Chloride; Quinidine; Rheumatic Heart Disease; Syncope; Ventricular Fibrillation	1971
Quinidine-induced hypoprothrombinemic hemorrhage in patients on chronic warfarin therapy. Annals of internal medicine, 1968, Volume: 68, Issue:3 Topics: Adult; Aged; Anticoagulants; Blood Coagulation Factors; Drug Synergism; Female; Hemorrhage; Humans; Hypoprothrombinemias; Liver; Male; Prothrombin Time; Quinidine; Warfarin	1968
More on quinidine-induced hypoprothrombinemia. Annals of internal medicine, 1968, Volume: 69, Issue:5 Topics: Humans; Hypoprothrombinemias; Quinidine; Warfarin	1968
Possible quinidine-induced hemorrhage in a patient on warfarin sodium. The New England journal of medicine, 1969, Mar-27, Volume: 280, Issue:13 Topics: Aortic Valve Stenosis; Blood Coagulation; Drug Synergism; Hematuria; Humans; Male; Middle Aged; Prothrombin Time; Quinidine; Warfarin	1969
Effect of other drugs on oral anticoagulants. Maryland state medical journal, 1969, Volume: 18, Issue:10 Topics: Acetaminophen; Anticoagulants; Coumarins; Drug Antagonism; Drug Synergism; Heparin; Humans; Oxyphenbutazone; Phenylbutazone; Prothrombin Time; Quinidine; Thromboembolism; Vitamin K; Warfarin	1969
The interaction between cholestyramine and drugs. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:1 Topics: Adsorption; Animals; Aspirin; Bile Acids and Salts; Blood; Chlorothiazide; Cholestyramine Resin; Dogs; Intestinal Absorption; Nicotinic Acids; Phenobarbital; Phenylbutazone; Quinidine; Rats; Spectrophotometry; Tetracycline; Urine; Warfarin	1965
Unexpected events attending elective D.C. cardioversion for atrial fibrillation. Geriatrics, 1966, Volume: 21, Issue:11 Topics: Adult; Anesthesia, General; Atrial Fibrillation; Digitalis Glycosides; Electric Countershock; Female; Heparin; Humans; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Warfarin	1966
Lichen planus following quinidine therapy. The British journal of dermatology, 1967, Volume: 79, Issue:2 Topics: Female; Humans; Lichen Planus; Middle Aged; Myocardial Infarction; Quinidine; Warfarin	1967
Drug interactions with amiodarone. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Benzofurans; Blood Coagulation Disorders; Calcium; Digoxin; Drug Interactions; Drug Synergism; Heart Arrest; Humans; Kinetics; Quinidine; Tachycardia; Warfarin	1983
Metabolic side-effects and interactions. Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 75 Topics: Absorption; Adrenal Cortex Hormones; Aluminum Hydroxide; Antacids; Bicarbonates; Biological Availability; Calcium Carbonate; Dicumarol; Drug Interactions; Humans; Metabolic Diseases; Quinidine; Salicylates; Sodium Bicarbonate; Tetracyclines; Warfarin	1982
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jan-26, Volume: 57, Issue:4 Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin	1980
Drug interaction with coumarin derivative anticoagulants. British medical journal (Clinical research ed.), 1982, Sep-11, Volume: 285, Issue:6343 Topics: Coumarins; Drug Interactions; Quinidine	1982
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
[Intraocular hemorrhage due to systemic drugs]. Harefuah, 1982, Feb-15, Volume: 102, Issue:4 Topics: Adult; Aged; Aspirin; Dipyridamole; Eye Diseases; Female; Hemorrhage; Humans; Male; Middle Aged; Quinidine; Warfarin	1982
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers. The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10 Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin	1995
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:10 Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline	1997
Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:9 Topics: Alprazolam; Aryl Hydrocarbon Hydroxylases; B-Lymphocytes; Benzoflavones; Biotransformation; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Hypnotics and Sedatives; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Quinidine; Recombinant Proteins; Sulfaphenazole; Troleandomycin	1999
In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:6 Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Hepatocytes; Humans; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Quinidine; Recombinant Proteins; Warfarin	2001
Coumarin substrates for cytochrome P450 2D6 fluorescence assays. Analytical biochemistry, 2001, May-15, Volume: 292, Issue:2 Topics: Amino Acid Sequence; Catalysis; Coumarins; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Fluorescent Dyes; Humans; Kinetics; Microsomes, Liver; Molecular Sequence Data; Quinidine; Recombinant Proteins; Substrate Specificity	2001
Cytochrome P450 enzymes contributing to demethylation of maprotiline in man. Pharmacology & toxicology, 2002, Volume: 90, Issue:3 Topics: Cells, Cultured; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzymes; Humans; Ketoconazole; Kinetics; Maprotiline; Mephenytoin; Microsomes, Liver; Models, Biological; Quinidine; Sulfaphenazole; Theophylline	2002
Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities. Journal of medicinal chemistry, 2003, Jan-02, Volume: 46, Issue:1 Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Coumarins; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Ligands; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Protein Binding; Quinidine; Quinine; Rabbits; Rats; Sequence Homology, Amino Acid; Sparteine; Species Specificity	2003
Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes. Toxicology in vitro : an international journal published in association with BIBRA, 2003, Volume: 17, Issue:4 Topics: Animals; Antidepressive Agents; Antimalarials; Antitussive Agents; Calcium Channel Blockers; Cell Survival; Chlorzoxazone; Coloring Agents; Coumarins; Cryopreservation; Cytochrome P-450 Enzyme System; Dextromethorphan; Imipramine; In Vitro Techniques; Liver; Male; Microsomes, Liver; Muscle Relaxants, Central; Oxazines; Pharmaceutical Preparations; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Testosterone; Verapamil; Xanthenes	2003
[Therapy of myocardial infarct]. La Riforma medica, 1953, Feb-21, Volume: 67, Issue:8 Topics: Adenosine Triphosphate; Ascorbic Acid; Bile Acids and Salts; Coumarins; Diet; Folic Acid; Heparin; Humans; Hypnotics and Sedatives; Khellin; Magnesium Sulfate; Myocardial Infarction; Purines; Quinidine; Salts; Sympathomimetics; Vitamin B Complex; Vitamin E; Vitamins	1953
WARFARIN AND RED SQUILL. North Carolina medical journal, 1963, Volume: 24 Topics: Blood Transfusion; Hemorrhage; Humans; Milk; North Carolina; Plants, Medicinal; Quinidine; Rodenticides; Toxicology; Vitamin K; Warfarin	1963
EXTERNAL CARDIAC MASSAGE. Rocky Mountain medical journal, 1963, Volume: 60 Topics: Electric Countershock; Electric Stimulation Therapy; Heart Massage; Humans; Myocardial Infarction; Quinidine; Respiration, Artificial; Ventricular Fibrillation; Warfarin	1963
Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543. Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:12 Topics: Adolescent; Adult; Aged; Chromans; Coumarins; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Ketoconazole; Kinetics; Male; Mephenytoin; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Quinidine; Receptors, Leukotriene B4; Recombinant Proteins; Sulfaphenazole; Theophylline	2003
Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1 Topics: Animals; Drug Interactions; Hydroxylation; Metabolic Clearance Rate; Microsomes, Liver; Muscarinic Antagonists; Perfusion; Quinidine; Rabbits; Rats; Species Specificity; Warfarin	2004
Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4. Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:5 Topics: Animals; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Microsomes, Liver; Models, Biological; Piroxicam; Quinidine; Recombinant Proteins; Warfarin	2004
High-throughput solution-based medicinal library screening against human serum albumin. Analytical chemistry, 2005, Mar-01, Volume: 77, Issue:5 Topics: Acecainide; beta-Lactams; Chromatography, Gel; Chromatography, Liquid; Combinatorial Chemistry Techniques; Dansyl Compounds; Humans; Imipramine; Indomethacin; Pharmaceutical Preparations; Protein Binding; Quinidine; Reproducibility of Results; Sarcosine; Serum Albumin; Tandem Mass Spectrometry; Tryptophan; Warfarin	2005
Rate-limiting biotransformation of triamterene is mediated by CYP1A2. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:7 Topics: Caffeine; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Humans; Hydroxylation; Ketoconazole; Kinetics; Microsomes, Liver; Omeprazole; Quinidine; Substrate Specificity; Sulfuric Acid Esters; Theophylline; Triamterene	2005
Pre-equilibrium capillary zone electrophoresis or frontal analysis: advantages of plateau peak conditions in affinity capillary electrophoresis. Electrophoresis, 2005, Volume: 26, Issue:21 Topics: Benzoic Acid; Dextran Sulfate; Electrophoresis, Capillary; Humans; Kinetics; Protein Binding; Quinidine; Reproducibility of Results; Serum Albumin; Viscosity; Warfarin	2005
Biocomputational Prediction Approach Targeting FimH by Natural SGLT2 Inhibitors: A Possible Way to Overcome the Uropathogenic Effect of SGLT2 Inhibitor Drugs. Molecules (Basel, Switzerland), 2021, Jan-22, Volume: 26, Issue:3 Topics: Adhesins, Escherichia coli; Computational Biology; Computer Simulation; Coumarins; Diabetes Mellitus, Type 2; Escherichia coli Infections; Fimbriae Proteins; Humans; Isoflavones; Molecular Docking Simulation; Quinidine; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Urinary Tract Infections; Uropathogenic Escherichia coli	2021